# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/DNA_methylase.hmm.txt
# target sequence database:        proteomes/Amphimedon_queenslandica.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       DNA_methylase  [M=335]
Accession:   PF00145.17
Description: C-5 cytosine-specific DNA methylase
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence                       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------                       -----------
    1.7e-54  186.7   0.0    2.1e-54  186.4   0.0    1.1  1  tr|A0A1X7TJ66|A0A1X7TJ66_AMPQE  Cytosine-specific methyltransfer
    2.2e-52  179.8   0.0    2.2e-52  179.8   0.0    3.0  4  tr|A0A1X7VAU3|A0A1X7VAU3_AMPQE  DNA (cytosine-5)-methyltransfera
    3.2e-51  175.9   0.0    5.1e-51  175.3   0.0    1.3  1  tr|A0A1X7TKI6|A0A1X7TKI6_AMPQE  Cytosine-specific methyltransfer
    3.2e-38  133.2   0.0    5.3e-38  132.5   0.0    1.3  1  tr|A0A1X7U0G0|A0A1X7U0G0_AMPQE  Uncharacterized protein OS=Amphi
    7.2e-33  115.6   0.0    3.4e-23   83.8   0.0    2.2  2  tr|A0A1X7U3G5|A0A1X7U3G5_AMPQE  Uncharacterized protein OS=Amphi
    5.7e-17   63.3   0.0    1.1e-16   62.4   0.0    1.4  1  tr|A0A1X7V196|A0A1X7V196_AMPQE  Uncharacterized protein OS=Amphi
    5.3e-14   53.6   0.0    9.7e-14   52.7   0.0    1.6  1  tr|A0A1X7UGK9|A0A1X7UGK9_AMPQE  Uncharacterized protein OS=Amphi
    1.8e-07   32.1   0.0    2.1e-07   31.9   0.0    1.1  1  tr|A0A1X7TJC1|A0A1X7TJC1_AMPQE  Uncharacterized protein OS=Amphi
     0.0062   17.2   0.0      0.011   16.4   0.0    1.3  1  tr|A0A1X7TED2|A0A1X7TED2_AMPQE  Uncharacterized protein OS=Amphi
  ------ inclusion threshold ------
      0.024   15.2   0.0      0.059   14.0   0.0    1.7  1  tr|A0A1X7U0X0|A0A1X7U0X0_AMPQE  Uncharacterized protein OS=Amphi
      0.078   13.6   0.0       0.09   13.4   0.0    1.2  1  tr|A0A1X7T699|A0A1X7T699_AMPQE  Uncharacterized protein OS=Amphi
      0.079   13.6   0.0       0.09   13.4   0.0    1.2  1  tr|A0A1X7V411|A0A1X7V411_AMPQE  Uncharacterized protein OS=Amphi


Domain annotation for each sequence (and alignments):
>> tr|A0A1X7TJ66|A0A1X7TJ66_AMPQE  Cytosine-specific methyltransferase OS=Amphimedon queenslandica OX=400682 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  186.4   0.0   5.9e-58   2.1e-54       1     232 [.      76     313 ..      76     347 .. 0.82

  Alignments for each domain:
  == domain 1  score: 186.4 bits;  conditional E-value: 5.9e-58
                                     -EEEEES-TT-HHHHHHHHTT-EEEEEEE--TTTHHHHHHH-.-SEEEES-.TTTS-.......GS--.-SEEEE---G CS
                   DNA_methylase   1 lkfidLfaGiGGfrlgleaagfecvaaseidkkaaktYeanfkkvsigDit.kidkk.......klpediDlLvgGfPC 71 
                                     ++fidLfaG+GG+rl ++++g++cv+ +e+d+  ++tY+anf++++  D+    d+k       ++p ++D+L++GfPC
  tr|A0A1X7TJ66|A0A1X7TJ66_AMPQE  76 FRFIDLFAGVGGMRLPFDEIGGRCVFTAEWDRFSCETYKANFPEPIGSDHIlAGDIKpwaaepsSIP-SHDVLLAGFPC 153
                                     79****************************************9555555431334446666699***.6********** PP

                                     GGTECTSE........E--TTSGGG.......HHHHHHHHHHHHH--SEEEEEEEGGGGGGCCSHHHHHHHHHHH.HHT CS
                   DNA_methylase  72 qpfSvaGk........qkgfedtrg.......tLffeiiriikekkPkvfllENVkgLlkhdkgktlkvilekle.elG 134
                                     qpfS+aG                 g       tLf++ +rii++++P +fllENVk+L  hdkg+t+ +i   le elG
  tr|A0A1X7TJ66|A0A1X7TJ66_AMPQE 154 QPFSIAGVskknalgrP------HGflcetqgTLFYDLARIIDHHRPPIFLLENVKNLERHDKGRTFATIKHVLEvELG 226
                                     *******8554444433......334444445******************************************979** PP

                                     EEEEEEEEEGGGTT-SB--EEEEEEEEEGGG----------SS---GGG.....TSGGGTTS-EEBTTTB--GGGSSST CS
                   DNA_methylase 135 YevsykllnasdyGvpQnReRvfivgirkdlelnvlvkvkefrfpkkkdleasktlrdlleekseldeektalsdklve 213
                                     Y++++k++++s   vpQ+ReR+fivg++      + +  ++  +p+ +     ++l ++l++     + k++l+d+l++
  tr|A0A1X7TJ66|A0A1X7TJ66_AMPQE 227 YKIFHKVIDSSPW-VPQKRERLFIVGFKDHD---IDFDFEDIIVPDGQ----GPNLGSILQK---NVDPKYTLTDHLWN 294
                                     ***********98.*************9865...35777777777776....699******9...5899********** PP

                                     T-EE--.......S---HH CS
                   DNA_methylase 214 keekikkttkaseegypke 232
                                       ++ k+++ + ++g+ ++
  tr|A0A1X7TJ66|A0A1X7TJ66_AMPQE 295 YLISYKEKHRKAGNGFGYS 313
                                     9999999999999999962 PP

>> tr|A0A1X7VAU3|A0A1X7VAU3_AMPQE  DNA (cytosine-5)-methyltransferase OS=Amphimedon queenslandica OX=400682 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.3   2.7       5.8   2.1e+04     216     230 ..      90     104 ..      12     172 .. 0.45
   2 ?   -4.2   0.1       5.6     2e+04     175     199 ..     428     450 ..     416     460 .. 0.58
   3 ?   -0.6   0.1      0.43   1.6e+03     173     255 ..     731     812 ..     673     854 .. 0.66
   4 !  179.8   0.0     6e-56   2.2e-52       2     334 ..     989    1440 ..     988    1441 .. 0.78

  Alignments for each domain:
  == domain 1  score: -4.3 bits;  conditional E-value: 5.8
                                     EE--.......S--- CS
                   DNA_methylase 216 ekikkttkaseegyp 230
                                      +++ + ++ +e ++
  tr|A0A1X7VAU3|A0A1X7VAU3_AMPQE  90 PQKRSKVEEEKEEVS 104
                                     222211111111111 PP

  == domain 2  score: -4.2 bits;  conditional E-value: 5.6
                                     -SS---GGG.....TSGGGTTS-EE CS
                   DNA_methylase 175 efrfpkkkdleasktlrdlleekse 199
                                     ++++++k  +++++ +rd++e   +
  tr|A0A1X7VAU3|A0A1X7VAU3_AMPQE 428 KKTKQTK--ATTTPLVRDIFETFFK 450
                                     2233333..5789999999998543 PP

  == domain 3  score: -0.6 bits;  conditional E-value: 0.43
                                     ---SS---GGG.....TSGGGTTS-EEBTTTB--GGGSSSTT-EE--.......S---H.HHTS--B--TTS...-B-- CS
                   DNA_methylase 173 vkefrfpkkkdleasktlrdlleekseldeektalsdklvekeekikkttkaseegypk.elsrnridkveelkglsat 250
                                     + ++ +p++k +++++ + ++++ +  l+ee +++ d+++ +  + +  ++++ +g +  +  ++  ++++e++++ ++
  tr|A0A1X7VAU3|A0A1X7VAU3_AMPQE 731 TVHSAVPINKIESEKPKITNYSSFQ--LNEESYSIGDCVYLSPHTYSFPNVKKTSGTAAnKKQKKEEEEFDESEYPEKY 807
                                     4444444444344445555555543..7777777777776655544433333333333223333335555555555555 PP

                                     --S-S CS
                   DNA_methylase 251 rrksg 255
                                     r+ s+
  tr|A0A1X7VAU3|A0A1X7VAU3_AMPQE 808 RKVSD 812
                                     55444 PP

  == domain 4  score: 179.8 bits;  conditional E-value: 6e-56
                                      EEEEES-TT-HHHHHHHHTT.-EEEEEEE--TTTHHHHHHH-..-SEEEES-TTTS-.............GS--... CS
                   DNA_methylase    2 kfidLfaGiGGfrlgleaag.fecvaaseidkkaaktYeanfk.kvsigDitkidkk.............klpe..d 61  
                                      +++d faG+GG++ g+++ag  + ++a+eid+ aa+ ++ n++  +++ D  +i  +              lp+  d
  tr|A0A1X7VAU3|A0A1X7VAU3_AMPQE  989 RMLDVFAGCGGLSEGFHQAGvADSCWAVEIDEPAAQAFRLNNSqTTVFTDDCNILLSlvmegaktnsrgqLLPQkgD 1065
                                      899*****************99********************99555555444433346666777888987887667 PP

                                      -SEEEE---GGGTECTSE..E--TTSGGGHHHHHHHHHHHHH--SEEEEEEEGGGGGGCCSHHHHHHHHHHHHHTEE CS
                   DNA_methylase   62 iDlLvgGfPCqpfSvaGk..qkgfedtrgtLffeiiriikekkPkvfllENVkgLlkhdkgktlkvilekleelGYe 136 
                                      ++lL+gG+PCq+fS      ++   + +++L + +  + + ++P +fllENV++ ++ +k+ +lk  l  l ++GY+
  tr|A0A1X7VAU3|A0A1X7VAU3_AMPQE 1066 VELLCGGPPCQGFSGMNRfnSREYSQFKNSLVISYLSFCEYYRPRFFLLENVRNFVSFKKSMVLKLTLRCLVKMGYQ 1142
                                      **************988744666667778************************************************ PP

                                      EEEEEEEGGGTT-SB--EEEEEEEEEGGG----------SS---GGG.....TSGGGTTS-EE...BTTTB--GGGS CS
                   DNA_methylase  137 vsykllnasdyGvpQnReRvfivgirkdlelnvlvkvkefrfpkkkdleasktlrdlleekse...ldeektalsdk 210 
                                      +++ +l+a +yGvpQ R+R +i++   +++l ++++ +   f+     + + +++d++ e s    +   +t   ++
  tr|A0A1X7VAU3|A0A1X7VAU3_AMPQE 1143 CTFGVLQAGQYGVPQTRRRAIILAAAPGEKL-PHFPNPTHVFSPRA-CQLTVVVNDIKYEGSIrmdSAPYRTITVRD 1217
                                      ***************************9876.68888888888887.699*******99976676566666667777 PP

                                      SSTT-EE--.......S---H..HHTS--................................................ CS
                   DNA_methylase  211 lvekeekikkttkaseegypk..elsrnr................................................ 237 
                                       +++  +ik+ +   + +y+    ++++r                                                
  tr|A0A1X7VAU3|A0A1X7VAU3_AMPQE 1218 SMSDLPHIKNGSAVRSMNYNGepHCHYQRlmrgnqhqpvlydhickemnplvaarmrfipigpgsdwrdlpnkcirl 1294
                                      77888888877777777777677566665777778889999888888889999999999988888888888877775 PP

                                      ........B--TTS...-B----S-STT-................................................ CS
                   DNA_methylase  238 ........idkveelkglsatrrksgrge................................................ 258 
                                              +         + t++++++g+                                                
  tr|A0A1X7VAU3|A0A1X7VAU3_AMPQE 1295 sdgttapkL---------QYTHHDKKNGRaknkslrgvcpcatgqpcdssyrqygtlipwclphtgnrhnhwaglyg 1362
                                      444332221.........22222222222334445555666666666666666666666666666666666666666 PP

                                      ......-B-TTS---EEEETTEEE--T.TTGGG--B-BHHHHHHHHT--TT-----SBHHHHHHHHTS--HHHHHHH CS
                   DNA_methylase  259 ......klekelaeagklqknkerfkpviekkriRrLtprEaarlqGfPddfefgskksaaykqiGnsVpvpvieai 329 
                                              ++ +++ ++++k+++    v++++++R  ++rE+ar qGfPd+f f ++  ++ +q+Gn+Vp+p+++ai
  tr|A0A1X7VAU3|A0A1X7VAU3_AMPQE 1363 rlewdgFFSTTVTNPEPMGKQGR----VLHPEQHRVVSVRECARSQGFPDTFRFFGTILDKHRQVGNAVPPPLAKAI 1435
                                      55555555555555555666665....9************************************************* PP

                                      HHHHH CS
                   DNA_methylase  330 akeik 334 
                                      + eik
  tr|A0A1X7VAU3|A0A1X7VAU3_AMPQE 1436 GLEIK 1440
                                      *9997 PP

>> tr|A0A1X7TKI6|A0A1X7TKI6_AMPQE  Cytosine-specific methyltransferase OS=Amphimedon queenslandica OX=400682 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  175.3   0.0   1.4e-54   5.1e-51       4     334 ..       2     447 ..       1     448 [. 0.74

  Alignments for each domain:
  == domain 1  score: 175.3 bits;  conditional E-value: 1.4e-54
                                     EEES-TT-HHHHHHHHTT.-EEEEEEE--TTTHHHHHHH-..-SEEEES-TTTS-.............GS--...-SEE CS
                   DNA_methylase   4 idLfaGiGGfrlgleaag.fecvaaseidkkaaktYeanfk.kvsigDitkidkk.............klpe..diDlL 65 
                                     +d faG+GG++ g+++ag  + ++a+eid+ aa+ ++ n++  +++ D  +i  +             +lp+  d++lL
  tr|A0A1X7TKI6|A0A1X7TKI6_AMPQE   2 LDVFAGCGGLSEGFHQAGvADSCWAVEIDEPAAQAFRLNYSqTTVFTDDCNILLSlvmegaktnsrgqSLPQkgDVELL 80 
                                     79****************99********************99555555444433346666777888999998667**** PP

                                     EE---GGGTECTSE..E--TTSGGGHHHHHHHHHHHHH--SEEEEEEEGGGGGGCCSHHHHHHHHHHHHHTEEEEEEEE CS
                   DNA_methylase  66 vgGfPCqpfSvaGk..qkgfedtrgtLffeiiriikekkPkvfllENVkgLlkhdkgktlkvilekleelGYevsykll 142
                                     +gG+PCq+fS      ++   + +++L + +  + + ++P++fllE V++ ++ +k+ +lk  l  l ++GY++++ +l
  tr|A0A1X7TKI6|A0A1X7TKI6_AMPQE  81 CGGPPCQGFSGMNIfnSREYSQFKNSLVISYLSFCEYYRPQFFLLESVRNFVSFKKSMVLKLTLRCLVKMGYQCTFGVL 159
                                     **********988754777778888****************************************************** PP

                                     EGGGTT-SB--EEEEEEEEEGGG----------SS---GGG.....TSGGGTTS-EE...BTTTB--GGGSSSTT-EE- CS
                   DNA_methylase 143 nasdyGvpQnReRvfivgirkdlelnvlvkvkefrfpkkkdleasktlrdlleekse...ldeektalsdklvekeeki 218
                                     +a +yGvpQ R+R +i++   +++l ++++ +   f+     + + + +d++ e s    +   +t   ++ +++  +i
  tr|A0A1X7TKI6|A0A1X7TKI6_AMPQE 160 QAGQYGVPQTRRRAIILAAAPGEKL-PHFPNPTHVFSPRA-CQLTVVANDIKYEGSIrmdSAPYRTITVRDSMSDLPHI 236
                                     *********************9876.58888888888887.68899999999886656555555666666677777777 PP

                                     -.......S---H..HHTS--.......................................................... CS
                   DNA_methylase 219 kkttkaseegypk..elsrnr.......................................................... 237
                                     k+ +   + +y+    ++++r                                                          
  tr|A0A1X7TKI6|A0A1X7TKI6_AMPQE 237 KNGSAVRSMNYNGepHCHYQRlvrgkshrgtsgnqhqpvlyghickemsplvaarmrylpigpgsdwrdlpnkcirlsd 315
                                     7666666666665665555555555555555555555666666655566666666666666655555555555544333 PP

                                     B--TTS...-B----S-STT--B-TTS---EEEETTEEE--T..................................... CS
                   DNA_methylase 238 idkveelkglsatrrksgrgeklekelaeagklqknkerfkp..................................... 279
                                                          ++ ++l+ +    kn+++ ++                                     
  tr|A0A1X7TKI6|A0A1X7TKI6_AMPQE 316 G--------------------TTAPKLQYTHHDKKNGRHKNKslrgvcscatgqpcdsfyrqygtlipcnhgayhiqvt 374
                                     0....................3333333333333333332224444444444444444444444444444445556666 PP

                                     ...................TTGGG--B-BHHHHHHHHT--TT-----SBHHHHHHHHTS--HHHHHHHHHHHH CS
                   DNA_methylase 280 ..................viekkriRrLtprEaarlqGfPddfefgskksaaykqiGnsVpvpvieaiakeik 334
                                                       v++++++R  +++E+ar qGfPd+f f ++  ++ +q+Gn+Vp+p++eai+ eik
  tr|A0A1X7TKI6|A0A1X7TKI6_AMPQE 375 dtiigrgfmeepmgkqgrVLHPEQHRVVSVKECARSQGFPDTFHFFGTILDKHRQVGNAVPPPLAEAIGLEIK 447
                                     666666666666777777***************************************************9997 PP

>> tr|A0A1X7U0G0|A0A1X7U0G0_AMPQE  Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  132.5   0.0   1.5e-41   5.3e-38       3     329 ..      34     366 ..      32     370 .. 0.78

  Alignments for each domain:
  == domain 1  score: 132.5 bits;  conditional E-value: 1.5e-41
                                     EEEES-TT-HHHHHHHHTT..-EEEEEEE--TTTHHHHHHH-...-SEEEES-TTTS-GS--..-SEEEE---GGGTEC CS
                   DNA_methylase   3 fidLfaGiGGfrlgleaag..fecvaaseidkkaaktYeanfk..kvsigDitkidkkklpe.diDlLvgGfPCqpfSv 76 
                                     ++++ +GiGG +++ +++g   ++ aa++i+ +a ++Y+ nf+  kv + +i  ++ ++l      l++ ++PCqpf  
  tr|A0A1X7U0G0|A0A1X7U0G0_AMPQE  34 VVEFYSGIGGWHYAIRETGlnLKILAAVDINTTANQVYKHNFPntKVLQRNILGLSAQELDSfLANLFTLSPPCQPFTR 112
                                     799****************999*********************9999999999999999997669************** PP

                                     TSEE--TTSGGGHHHHHHHHHHHHH-..-SEEEEEEEGGGGGGCCSHHHHHHHHHHHHHTEEEEEEEEEGGGTT-SB-- CS
                   DNA_methylase  77 aGkqkgfedtrgtLffeiiriikekk..PkvfllENVkgLlkhdkgktlkvilekleelGYevsykllnasdyGvpQnR 153
                                     +Gk+++  d r + ff  + i+ + +  P+++++ENVkg   +   +t  +++  l+elGY+++  l+  +++G+p +R
  tr|A0A1X7U0G0|A0A1X7U0G0_AMPQE 113 QGKNEDDIDYRTDSFFHLMGILSAMQkpPQYIMMENVKGFELS---RTRGHFVHVLKELGYTFQEYLISPKQFGIPNSR 188
                                     ***********************98888***********9888...6678889999*********************** PP

                                     EEEEEEEEEGGG----------SS---GGG.............TSGGGTTS-EEBTTTB--GGGSSSTT-EE--..... CS
                   DNA_methylase 154 eRvfivgirkdlelnvlvkvkefrfpkkkd........leasktlrdlleekseldeektalsdklvekeekikkttka 224
                                      R ++++ +++++ +   +  ++++++ k+         + + ++ ++l++ se+d ++  + d ++ek+++  +  + 
  tr|A0A1X7U0G0|A0A1X7U0G0_AMPQE 189 LRYYLLARLSPRNFK--AAPLQDTVEHLKYyiptsfhdIHLKCDISSYLDDLSEIDVQQFLVPDRILEKYAQGLD--IV 263
                                     ***********9876..4444444444444455557776777777777777777788888888888887776643..33 PP

                                     ..S---HHHTS--B--TTS...-B----S-STT--B-TTS---EEEETTEEE--T.TTGGG--B-BHHHHHHHHT--TT CS
                   DNA_methylase 225 seegypkelsrnridkveelkglsatrrksgrgeklekelaeagklqknkerfkpviekkriRrLtprEaarlqGfPdd 303
                                     s ++ + ++   r  + + + + s ++++++ +  l  + ++ +k+++++    +++++ + R +tp+E+a+l++fP +
  tr|A0A1X7U0G0|A0A1X7U0G0_AMPQE 264 SAKSHS-SCCFTRGYYHYAVGTGSVLHHDCSVDLALAYQCYAEQKNNCDGI---KSLKELKLRYFTPQEVAKLMSFPAS 338
                                     333333.23333223333333333333333332233334444444444443...3899********************* PP

                                     -----SBH..HHHHHHHTS--HHHHHHH CS
                   DNA_methylase 304 fefgskks..aaykqiGnsVpvpvieai 329
                                      +f+++ s  + yk++GnsV+v v+  +
  tr|A0A1X7U0G0|A0A1X7U0G0_AMPQE 339 HTFPTSVSnkQCYKLLGNSVNVFVVATL 366
                                     7776666666************998765 PP

>> tr|A0A1X7U3G5|A0A1X7U3G5_AMPQE  Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.7   0.0   2.7e-10   9.8e-07       4      48 ..       2      48 ..       1      54 [. 0.89
   2 !   83.8   0.0   9.3e-27   3.4e-23      55     232 ..     104     288 ..      91     369 .. 0.77

  Alignments for each domain:
  == domain 1  score: 29.7 bits;  conditional E-value: 2.7e-10
                                    EEES-TT-HHHHHHHHTT.-EEEEEEE--TTTHHHHHHH-..-SEEE CS
                   DNA_methylase  4 idLfaGiGGfrlgleaag.fecvaaseidkkaaktYeanfk.kvsig 48
                                    +d faG+GG++ g+++ag  + ++a+eid+ aa+ ++ n++  +++ 
  tr|A0A1X7U3G5|A0A1X7U3G5_AMPQE  2 LDVFAGCGGLSEGFHQAGvADSCWAVEIDEPAAQAFRLNYSqTTVFT 48
                                    79****************99********************9655554 PP

  == domain 2  score: 83.8 bits;  conditional E-value: 9.3e-27
                                     S-GS--...-SEEEE---GGGTECTSE..E--TTSGGGHHHHHHHHHHHHH--SEEEEEEEGGGGGGCCSHHHHHHHHH CS
                   DNA_methylase  55 kkklpe..diDlLvgGfPCqpfSvaGk..qkgfedtrgtLffeiiriikekkPkvfllENVkgLlkhdkgktlkvilek 129
                                      ++lp+  d++lL+gG+PCq+fS      ++   + +++L + +  + + ++P++fllE V++ ++ +k+ +lk  l  
  tr|A0A1X7U3G5|A0A1X7U3G5_AMPQE 104 GQSLPQkgDVELLCGGPPCQGFSGMNRfnSREYSQFKNSLVISYLSFCEYYRPQFFLLESVRNFVSFKKSMVLKLTLRC 182
                                     446776557**************988744666667778***************************************** PP

                                     HHHHTEEEEEEEEEGGGTT-SB--EEEEEEEEEGGG----------SS---GGG.....TSGGGTTS-EE...BTTTB- CS
                   DNA_methylase 130 leelGYevsykllnasdyGvpQnReRvfivgirkdlelnvlvkvkefrfpkkkdleasktlrdlleekse...ldeekt 205
                                     l ++GY++++ +l+a +yGvpQ R+R +i++   +++l ++++ +   f+     + + +++d++ e s    +   +t
  tr|A0A1X7U3G5|A0A1X7U3G5_AMPQE 183 LVKMGYQCTFGVLQAGQYGVPQTRRRAIILAAAPGEKL-PHFPNPTHAFSPRV-CQLTVVVNDIKYEGSIrmdSAPYRT 259
                                     *********************************99876.68888888888887.6899999999988655544444444 PP

                                     -GGGSSSTT-EE--.......S---H..H CS
                   DNA_methylase 206 alsdklvekeekikkttkaseegypk..e 232
                                        ++ +++  +ik+ +   + +y+    
  tr|A0A1X7U3G5|A0A1X7U3G5_AMPQE 260 ITVRDSMSDLPHIKNGSAVRSMNYNGepH 288
                                     55555555555555554444444443343 PP

>> tr|A0A1X7V196|A0A1X7V196_AMPQE  Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   62.4   0.0     3e-20   1.1e-16       1     120 [.     635     767 ..     635     782 .. 0.90

  Alignments for each domain:
  == domain 1  score: 62.4 bits;  conditional E-value: 3e-20
                                     -EEEEES-TT-HHHHHHHHTT..-EEEEEEE--TTTHHHHHHH-..-SEEEES-TTTS-GS--...-SEEEE---GGGT CS
                   DNA_methylase   1 lkfidLfaGiGGfrlgleaag..fecvaaseidkkaaktYeanfk.kvsigDitkidkkklpe.d.iDlLvgGfPCqpf 74 
                                     ++++ Lf+GiG   l l++ g  +e+++aseid++a+k+ + +++   + g i+++++k+++    +Dl+ gG PC++ 
  tr|A0A1X7V196|A0A1X7V196_AMPQE 635 MRVLGLFDGIGTGLLVLKELGinVEVYIASEIDPDAIKVSRIKHPeIIHVGAIEQVTEKEVRSwGpFDLVFGGSPCNDL 713
                                     78999****************9999********************88899*********9997647************* PP

                                     ECTS.EE--TTSGGGHHHHHHHHHHHHH-.......-SEEEEEEEGGGGGGCCS CS
                   DNA_methylase  75 SvaG.kqkgfedtrgtLffeiiriikekk.......PkvfllENVkgLlkhdkg 120
                                     S+   ++kg+ d  g+Lffe+ ri+   k       P + l ENV  +  +dk+
  tr|A0A1X7V196|A0A1X7V196_AMPQE 714 SIVNpARKGIYDGTGKLFFEFFRILSYAKpqpqderPFFWLYENVVSMRAPDKK 767
                                     *98736*******************99886666666778999***999999885 PP

>> tr|A0A1X7UGK9|A0A1X7UGK9_AMPQE  Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   52.7   0.0   2.7e-17   9.7e-14     252     333 ..     167     278 ..       6     280 .. 0.63

  Alignments for each domain:
  == domain 1  score: 52.7 bits;  conditional E-value: 2.7e-17
                                     -S-STT-......................-B-TTS---EEEETTEEE--T............................T CS
                   DNA_methylase 252 rksgrge......................klekelaeagklqknkerfkp...........................vi 281
                                     +++++g+                      +                   +                           v+
  tr|A0A1X7UGK9|A0A1X7UGK9_AMPQE 167 HDKKNGRaknkslrgvcscatgqpcdssyR-------------------QymgplyhgayhiqaidtiiglgsmggfVL 226
                                     222222222333333334444444333330...................144444444444444555555555555589 PP

                                     TGGG--B-BHHHHHHHHT--TT-----SBHHHHHHHHTS--HHHHHHHHHHH CS
                   DNA_methylase 282 ekkriRrLtprEaarlqGfPddfefgskksaaykqiGnsVpvpvieaiakei 333
                                     +++++   ++rE+ar qGfPd+f f ++  ++ +q+Gn+Vp+p+++ai+ ei
  tr|A0A1X7UGK9|A0A1X7UGK9_AMPQE 227 HPEQHQVVSVRECARSQGFPDTFHFFGTILDKHRQVGNAVPPPLAKAIGLEI 278
                                     ************************************************9887 PP

>> tr|A0A1X7TJC1|A0A1X7TJC1_AMPQE  Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.9   0.0   5.9e-11   2.1e-07     299     332 ..       2      39 ..       1      41 [. 0.87

  Alignments for each domain:
  == domain 1  score: 31.9 bits;  conditional E-value: 5.9e-11
                                     T--TT....-----SBHHHHHHHHTS--HHHHHHHHHH CS
                   DNA_methylase 299 GfPdd....fefgskksaaykqiGnsVpvpvieaiake 332
                                     Gf ++    ++f++++++ay+q+Gn+V+vpv++a+a+ 
  tr|A0A1X7TJC1|A0A1X7TJC1_AMPQE   2 GFQKSdgskWKFPVSDAQAYRQMGNAVVVPVVRALARL 39 
                                     666666667*************************9985 PP

>> tr|A0A1X7TED2|A0A1X7TED2_AMPQE  Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.4   0.0     3e-06     0.011       2      70 ..      64     140 ..      63     141 .. 0.93

  Alignments for each domain:
  == domain 1  score: 16.4 bits;  conditional E-value: 3e-06
                                     EEEEES-TT-HHHHHHHHTT-EEEEEEE--TTTHHHHHHH-..........-SEEEES-TTTS-GS--.-SEEEE--- CS
                   DNA_methylase   2 kfidLfaGiGGfrlgleaagfecvaaseidkkaaktYeanfk.........kvsigDitkidkkklpediDlLvgGfP 70 
                                     ++idL +G G + lg    g e v a++id++++k+ + n +         +v++ Di++id +k+    D ++  +P
  tr|A0A1X7TED2|A0A1X7TED2_AMPQE  64 TVIDLGCGSGILGLGCLLLGAERVTAIDIDPNCVKLTQSNANdlgissdqlSVIQCDIKTIDTDKFDR-ADTVIMNPP 140
                                     58********************************************9999999999999999999995.998887776 PP

>> tr|A0A1X7U0X0|A0A1X7U0X0_AMPQE  Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.0   0.0   1.6e-05     0.059       2      70 ..      64     140 ..      63     141 .. 0.93

  Alignments for each domain:
  == domain 1  score: 14.0 bits;  conditional E-value: 1.6e-05
                                     EEEEES-TT-HHHHHHHHTT-EEEEEEE--TTTHHHHHHH-..........-SEEEES-TTTS-GS--.-SEEEE--- CS
                   DNA_methylase   2 kfidLfaGiGGfrlgleaagfecvaaseidkkaaktYeanfk.........kvsigDitkidkkklpediDlLvgGfP 70 
                                     +++dL +G G + lg    g e v a++id++++k+ + n +         +v++ Di++id +++    D ++  +P
  tr|A0A1X7U0X0|A0A1X7U0X0_AMPQE  64 TVVDLGCGSGILGLGCLLLGAERVTAIDIDPNCVKLTQSNANdlgissdqlSVIQYDIKTIDTDQFDR-ADTVIMNPP 140
                                     589*******************************************999999999*******99*995.998887776 PP

>> tr|A0A1X7T699|A0A1X7T699_AMPQE  Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.0   2.5e-05      0.09     105     156 ..      20      71 ..      19     151 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 2.5e-05
                                     EEEEEEEGGGGGGCCSHHHHHHHHHHHHHTEEEEEEEEEGGGTT-SB--EEE CS
                   DNA_methylase 105 vfllENVkgLlkhdkgktlkvilekleelGYevsykllnasdyGvpQnReRv 156
                                     ++ +E V  L+++++++   ++++kle lGY+v  ++++ s  +vp  R  +
  tr|A0A1X7T699|A0A1X7T699_AMPQE  20 FLHMEMVSYLVSSKEKEDQGELISKLEALGYGVGARMMERSCRDVPRFRTEL 71 
                                     788********************************99999999999888655 PP

>> tr|A0A1X7V411|A0A1X7V411_AMPQE  Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.0   2.5e-05      0.09     105     156 ..      20      71 ..      19     151 .. 0.78

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 2.5e-05
                                     EEEEEEEGGGGGGCCSHHHHHHHHHHHHHTEEEEEEEEEGGGTT-SB--EEE CS
                   DNA_methylase 105 vfllENVkgLlkhdkgktlkvilekleelGYevsykllnasdyGvpQnReRv 156
                                     ++ +E V  L+++++++   ++++kle lGY+v  ++++ s  +vp  R  +
  tr|A0A1X7V411|A0A1X7V411_AMPQE  20 FLHMEMVSYLVSSKEKEDQGELISKLEALGYGVGARMMERSCRDVPRFRTEL 71 
                                     788********************************99999999999888655 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (335 nodes)
Target sequences:                        43435  (14716620 residues searched)
Passed MSV filter:                      3056  (0.070358); expected 868.7 (0.02)
Passed bias filter:                     1262  (0.0290549); expected 868.7 (0.02)
Passed Vit filter:                       135  (0.00310809); expected 43.4 (0.001)
Passed Fwd filter:                        15  (0.000345344); expected 0.4 (1e-05)
Initial search space (Z):              43435  [actual number of targets]
Domain search space  (domZ):              12  [number of targets reported over threshold]
# CPU time: 0.56u 0.03s 00:00:00.59 Elapsed: 00:00:00.17
# Mc/sec: 29000.40
//
[ok]