# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/DNA_methylase.hmm.txt
# target sequence database: proteomes/Danio_rerio.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: DNA_methylase [M=335]
Accession: PF00145.17
Description: C-5 cytosine-specific DNA methylase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
2.8e-49 168.8 0.0 1.1e-48 166.9 0.0 2.1 1 tr|F1RCN0|F1RCN0_DANRE DNA (cytosine-5)-methyltransferase OS
6.1e-43 147.9 0.0 7.6e-43 147.6 0.0 1.1 1 tr|Q588C1|Q588C1_DANRE DNA methyltransferase OS=Danio rerio
1.1e-19 71.5 4.5 1.3e-16 61.4 0.0 3.4 4 tr|A3QJV0|A3QJV0_DANRE DNA (cytosine-5-)-methyltransferase 3
1.9e-17 64.2 0.0 1.5e-13 51.3 0.0 2.4 2 tr|Q588C6|Q588C6_DANRE DNA (cytosine-5-)-methyltransferase 3
4.7e-17 62.8 0.0 4.8e-12 46.4 0.0 2.3 2 tr|B8JLQ7|B8JLQ7_DANRE DNA (cytosine-5-)-methyltransferase 3
8.3e-17 62.0 0.0 1.1e-12 48.5 0.0 2.4 2 tr|F1R1K5|F1R1K5_DANRE DNA (cytosine-5-)-methyltransferase 3
1.3e-16 61.4 0.2 5.1e-13 49.6 0.0 2.6 3 tr|E7F6H4|E7F6H4_DANRE DNA (cytosine-5-)-methyltransferase 3
3.5e-15 56.7 0.0 6.3e-12 46.0 0.0 2.5 2 tr|A3QJU7|A3QJU7_DANRE DNA (cytosine-5-)-methyltransferase b
------ inclusion threshold ------
0.031 14.1 0.0 0.046 13.6 0.0 1.2 1 sp|A3KP85|ETKMT_DANRE Electron transfer flavoprotein beta s
0.04 13.8 0.0 0.075 12.9 0.0 1.4 1 tr|E9QCX1|E9QCX1_DANRE Methyltransferase-like 5 OS=Danio rer
0.11 12.3 0.0 0.18 11.6 0.0 1.2 1 sp|Q0P466|TYW2_DANRE tRNA wybutosine-synthesizing protein
0.12 12.2 1.2 0.16 11.8 1.2 1.1 1 tr|F6NL10|F6NL10_DANRE R3H domain-containing 4 OS=Danio reri
2.6 7.8 8.7 4 7.2 0.0 2.3 2 tr|Q5RHJ0|Q5RHJ0_DANRE Si:ch211-241j12.3 OS=Danio rerio OX=7
Domain annotation for each sequence (and alignments):
>> tr|F1RCN0|F1RCN0_DANRE DNA (cytosine-5)-methyltransferase OS=Danio rerio OX=7955 GN=dnmt1 PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 166.9 0.0 5.3e-52 1.1e-48 2 334 .. 1024 1476 .. 1023 1477 .. 0.78
Alignments for each domain:
== domain 1 score: 166.9 bits; conditional E-value: 5.3e-52
EEEEES-TT-HHHHHHHHTT.-EEEEEEE--TTTHHHHHHH-...-SEEEES-TTTS-............GS--...-SEEEE-- CS
DNA_methylase 2 kfidLfaGiGGfrlgleaag.fecvaaseidkkaaktYeanfk..kvsigDitkidkk............klpe..diDlLvgGf 69
+++d f+G+GG++ g+++ag e+ +a+e+++ aa+ ++ n++ v ++D + + k klp+ d+++L+gG+
tr|F1RCN0|F1RCN0_DANRE 1024 RTLDVFSGCGGLSEGFHQAGiSETHWAIEMWDPAAQAFRLNNPgtTVFTEDCNVLLKLvmsgektnslgqKLPQkgDVEMLCGGP 1108
789*****************99**********************755555655554445666677889999998766******** PP
-GGGTECTSE..E--TTSGGGHHHHHHHHHHHHH--SEEEEEEEGGGGGGCCSHHHHHHHHHHHHHTEEEEEEEEEGGGTT-SB- CS
DNA_methylase 70 PCqpfSvaGk..qkgfedtrgtLffeiiriikekkPkvfllENVkgLlkhdkgktlkvilekleelGYevsykllnasdyGvpQn 152
PCq+fS ++ + +++L + + + + ++Pk+fllENV++ ++ +++ +lk l l +GY++++ +l+a +yGv+Q
tr|F1RCN0|F1RCN0_DANRE 1109 PCQGFSGMNRfnSRTYSKFKNSLVVSYLSYCDYYRPKFFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQT 1193
******887654666677777**************************************************************** PP
-EEEEEEEEEGGG---...............-------SS---GGG..............TSGGGTTS-EEBTTTB--GGGSSST CS
DNA_methylase 153 ReRvfivgirkdleln...............vlvkvkefrfpkkkd.........leasktlrdlleekseldeektalsdklve 213
R+R +i++ +++l ++v+v e+++ ++ ++++t+ dl+e + a + ++
tr|F1RCN0|F1RCN0_DANRE 1194 RRRAIILAAAPGEKLPrypeplhvfapracsLSVAVDEKKYVSNVTrgnggiyrtITVRDTMSDLPEI-----RNGAAALEISYN 1273
***********998889998888888777764444444444444446777844444444444444443.....233333444455 PP
T-EE--.......S---HHHTS--.................................B--TTS...-B----S-STT-....... CS
DNA_methylase 214 keekikkttkaseegypkelsrnr.................................idkveelkglsatrrksgrge....... 258
e +++ +++ +++y+ + r+ ++++ +k+l+ t+ ++++g+
tr|F1RCN0|F1RCN0_DANRE 1274 GEPQSWFQRQIRGSQYQ-PILRDHickdmsalvaarmrniplapgsdwrdlpnfevrLRDGTTTKKLRYTHPDKKNGRsgtgalr 1357
55555556666666666.3333334555567777778999999999999999998886666666666666666666667778898 PP
...............................................-B-TTS---EEEETTEEE--T.TTGGG--B-BHHHHHH CS
DNA_methylase 259 ...............................................klekelaeagklqknkerfkpviekkriRrLtprEaar 296
++ +++ ++++k+++ v++++++R ++rE+ar
tr|F1RCN0|F1RCN0_DANRE 1358 gvcscsegkpcdpadrqfntlipwclphtgnrhnhwaglygrlewdgFFSTTVTNPEPMGKQGR----VLHPEQHRVVSVRECAR 1438
8888888888888888888777777777777777777777766666555566666666666666....9**************** PP
HHT--TT-----SBHHHHHHHHTS--HHHHHHHHHHHH CS
DNA_methylase 297 lqGfPddfefgskksaaykqiGnsVpvpvieaiakeik 334
qGfPd++ f ++ ++ +q+Gn+Vp+p+ +ai+ e+k
tr|F1RCN0|F1RCN0_DANRE 1439 SQGFPDTYRFFGNVLDKHRQVGNAVPPPLSKAIGLEVK 1476
*********************************99877 PP
>> tr|Q588C1|Q588C1_DANRE DNA methyltransferase OS=Danio rerio OX=7955 GN=trdmt1 PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 147.6 0.0 3.9e-46 7.6e-43 2 331 .. 8 376 .. 7 380 .. 0.69
Alignments for each domain:
== domain 1 score: 147.6 bits; conditional E-value: 3.9e-46
EEEEES-TT-HHHHHHHHTT..-EEEEEEE--TTTHHHHHHH-...-SEEEES-TTTS-GS--..-SEEEE---GGGTECTSEE--T CS
DNA_methylase 2 kfidLfaGiGGfrlgleaag..fecvaaseidkkaaktYeanfk..kvsigDitkidkkklpe.diDlLvgGfPCqpfSvaGkqkgf 83
++++L +GiGG++++l++ e+vaa++ + +a +Y+ nf+ + + i+ + +++ ++D+++ ++PCqpf G q +
tr|Q588C1|Q588C1_DANRE 8 RVFELYSGIGGMHYALKESLvpAEVVAAVDVNTTANLIYKHNFPttQLLPKTIEGMTLQDFDRlNFDMILMSPPCQPFTRIGLQGDV 94
899**************99999**********************765555556666666888888********************** PP
TSGGGHHHHHHHHHHH..HH--SEEEEEEEGGGGGGCCSHHHHHHHHHHHHHTEEEEEEEEEGGGTT-SB--EEEEEEEEEGGG--- CS
DNA_methylase 84 edtrgtLffeiiriik..ekkPkvfllENVkgLlkhdkgktlkvilekleelGYevsykllnasdyGvpQnReRvfivgirkdleln 168
+d+r + f +i ++ +k+P ++llENVkg ++ + + +l++l+e++Y+++ l+ G+p +R R f+++ r +++ +
tr|Q588C1|Q588C1_DANRE 95 ADPRTKSFLYILDLLPrlSKRPRFILLENVKGFESSA---ARDALLQTLRECDYSFQEFLISPTSLGIPNSRLRYFLIAKRAPETFS 178
***************722578************9995...578889*************************************9988 PP
.....................-------SS---GGG..............TSGGGTTS-EE........BTTTB--GGGSSSTT-EE CS
DNA_methylase 169 .....................vlvkvkefrfpkkkd.........leasktlrdlleekse........ldeektalsdklvekeek 217
v + +++++ +l++e+ + ++e +l d l e+
tr|Q588C1|Q588C1_DANRE 179 fpvsteiiegfpmsestdglsV-------------PydhptssasEREKTIMFKLETEE-DlerkrkqnSQESVRRLLDFLQEE--- 248
7544444444333333333221.............022222222211222222222221.111111112333333333333333... PP
--.......S---HHHTS--...........................B--TTS...-B----S-STT-......-B-TTS---EEEE CS
DNA_methylase 218 ikkttkaseegypkelsrnr...........................idkveelkglsatrrksgrge......klekelaeagklq 271
++v +kg+ ++++ +g+ le+ +
tr|Q588C1|Q588C1_DANRE 249 -------------------EedmepyllppktllryalvmdivqpssRRSVCFTKGYGHYVEGTGSVLqscmdvDLETVFK------ 310
...................13344444444455444555555566665666666666666666664224444333333333...... PP
TTEEE--T............TTGGG--B-BHHHHHHHHT--TT-----SBH..HHHHHHHTS--HHHHHHHHH CS
DNA_methylase 272 knkerfkp...........viekkriRrLtprEaarlqGfPddfefgskks..aaykqiGnsVpvpvieaiak 331
+ + + R +tprE rl+GfPd f+f+ s ++y+++Gns++v v+ ++++
tr|Q588C1|Q588C1_DANRE 311 -------NldqlseedklkQLLRLKLRYFTPREISRLMGFPDHFTFPKHISfkQQYRVLGNSLNVHVVSHLIR 376
.......2223333333345788899************************999****************9987 PP
>> tr|A3QJV0|A3QJV0_DANRE DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.2 OS=Danio rerio OX=7955 GN=dnmt3bb.2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -2.3 0.4 1.6 3.1e+03 187 224 .. 138 170 .. 105 209 .. 0.46
2 ? -1.1 0.1 0.69 1.4e+03 200 264 .. 963 1013 .. 868 1036 .. 0.46
3 ! 61.4 0.0 6.7e-20 1.3e-16 1 119 [. 1164 1296 .. 1164 1304 .. 0.89
4 ! 9.9 0.0 0.0003 0.59 261 331 .. 1363 1434 .. 1325 1438 .. 0.74
Alignments for each domain:
== domain 1 score: -2.3 bits; conditional E-value: 1.6
..TSGGGTTS-EE..BTTTB--GGGSSSTT-EE--..... CS
DNA_methylase 187 sktlrdlleekse..ldeektalsdklvekeekikkttka 224
s +++ +++e++ +++e+t+ ++k+ e+ +
tr|A3QJV0|A3QJV0_DANRE 138 SREFETIEKENVSslYNTEETSSNQKTQHVEK-------T 170
33333333333333222222222221111111.......1 PP
== domain 2 score: -1.1 bits; conditional E-value: 0.69
BTTTB--GGGSSSTT-EE--.......S---HHHTS--B--TTS...-B----S-STT--B-TTS CS
DNA_methylase 200 ldeektalsdklvekeekikkttkaseegypkelsrnridkveelkglsatrrksgrgeklekel 264
++ ++++ +++ + ++k ++++++++p+ + ++r++s++ +++ e
tr|A3QJV0|A3QJV0_DANRE 963 KKRLYSKWNGRSMQTVKIRRKYKQRNKNIIPT--------------VQIESRQNSQKRHQMVHEF 1013
33333333333333333333333333333333..............2222233333223333333 PP
== domain 3 score: 61.4 bits; conditional E-value: 6.7e-20
-EEEEES-TT-HHHHHHHHTT..-EEEEEEE--TTTHHHHHHH-...-SEEEES-TTTS-GS--...-SEEEE---GGGTECTS. CS
DNA_methylase 1 lkfidLfaGiGGfrlgleaag..fecvaaseidkkaaktYeanfk..kvsigDitkidkkklpe.d.iDlLvgGfPCqpfSvaG. 78
+++++Lf+Gi l l+ g +e ++aseid++ +++ n+ ++ D+++i+kk +++ +DlL+gG PC++ S+
tr|A3QJV0|A3QJV0_DANRE 1164 IRVLSLFDGIATGYLVLRDLGfkVEKYVASEIDEESITISMVNHDgkITQVDDVKNITKKHIEQwGpFDLLIGGSPCNDLSIVNp 1248
5899*****************888899*****************99899999********9997647**************9873 PP
EE--TTSGGGHHHHHHHHHHHHH-.......-SEEEEEEEGGGGGGCC CS
DNA_methylase 79 kqkgfedtrgtLffeiiriikekk.......PkvfllENVkgLlkhdk 119
++kg + g Lffe+ r+++ k P + l+ENV +++h k
tr|A3QJV0|A3QJV0_DANRE 1249 ARKGLYEGTGRLFFEYYRLLNVLKpkeddpqPFFWLFENVTFMQTHVK 1296
6*******************9988555555555889*******99966 PP
== domain 4 score: 9.9 bits; conditional E-value: 0.0003
-TTS---EEEETTEEE--T.TTGGG--B-BHHHHHHHHT--TT-----SBH..HHHHHHHTS--HHHHHHHHH CS
DNA_methylase 261 ekelaeagklqknkerfkpviekkriRrLtprEaarlqGfPddfefgskks..aaykqiGnsVpvpvieaiak 331
++ +++ k + n+ +f pv + + + E+ ++ GfP+ ++ + ++ +++G s +vpvi++++
tr|A3QJV0|A3QJV0_DANRE 1363 ITTRQNSLKQGTNDAHF-PVTMNGKDDHIWITELEKIFGFPKHYTDVKSMGrpQRQRVLGKSWSVPVIRHLLA 1434
33444444444455544.3788888889999*************876665567****************9986 PP
>> tr|Q588C6|Q588C6_DANRE DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.1 OS=Danio rerio OX=7955 GN=dnmt3bb.1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 51.3 0.0 7.6e-17 1.5e-13 1 120 [. 538 671 .. 538 688 .. 0.88
2 ! 10.5 0.0 0.0002 0.4 265 331 .. 739 807 .. 705 811 .. 0.76
Alignments for each domain:
== domain 1 score: 51.3 bits; conditional E-value: 7.6e-17
-EEEEES-TT-HHHHHHHHTT..-EEEEEEE--TTTHHHHHHH-...-SEEEES-TTTS-GS--...-SEEEE---GGGTECTS.EE CS
DNA_methylase 1 lkfidLfaGiGGfrlgleaag..fecvaaseidkkaaktYeanfk..kvsigDitkidkkklpe.d.iDlLvgGfPCqpfSvaG.kq 80
+++++Lf+Gi l l+ g ++ ++ase ++ + + + +++ + +D+++i+ k+++e +D+++gG PC++ S+ ++
tr|Q588C6|Q588C6_DANRE 538 IRVLSLFDGIATGYLVLRDLGfkVDLYIASEVCEDSISVGAVRHEgkIQYVHDVRNITRKNIAEwGpFDMVIGGSPCNDLSIVNpAR 624
5899*****************88889******************99888899**********98747**************98736* PP
--TTSGGGHHHHHHHHHHHHH-.......-SEEEEEEEGGGGGGCCS CS
DNA_methylase 81 kgfedtrgtLffeiiriikekk.......PkvfllENVkgLlkhdkg 120
kg + g Lffe+ r++ e k P + ++ENV + +dk+
tr|Q588C6|Q588C6_DANRE 625 KGLYEGTGRLFFEFYRLLSEAKpkegedrPFFWMFENVVAMSVNDKR 671
**********************5555555568899***999988886 PP
== domain 2 score: 10.5 bits; conditional E-value: 0.0002
---EEEETTEEE--T.TTGGG--B-BHHHHHHHHT--TT-----SBH..HHHHHHHTS--HHHHHHHHH CS
DNA_methylase 265 aeagklqknkerfkpviekkriRrLtprEaarlqGfPddfefgskks..aaykqiGnsVpvpvieaiak 331
+++++ + k + pv+ + ++ L E+ r+ GfP ++ s+ a+ k++G s +vpvi++++
tr|Q588C6|Q588C6_DANRE 739 TRSNSIKQGKDQHFPVMMNGKEDILWCTELERIFGFPVHYTDVSNMGrgARQKLLGRSWSVPVIRHLFA 807
233322222222335888888899999*************999888888*****************986 PP
>> tr|B8JLQ7|B8JLQ7_DANRE DNA (cytosine-5-)-methyltransferase 3 alpha a OS=Danio rerio OX=7955 GN=dnmt3aa PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 46.4 0.0 2.5e-15 4.8e-12 1 120 [. 575 708 .. 575 723 .. 0.85
2 ! 14.4 0.0 1.3e-05 0.027 259 332 .. 770 845 .. 727 848 .. 0.78
Alignments for each domain:
== domain 1 score: 46.4 bits; conditional E-value: 2.5e-15
-EEEEES-TT-HHHHHHHHTT..-EEEEEEE--TTTHHHHHHH-...-SEEEES-TTTS-GS--...-SEEEE---GGGTECTS.EE CS
DNA_methylase 1 lkfidLfaGiGGfrlgleaag..fecvaaseidkkaaktYeanfk..kvsigDitkidkkklpe.d.iDlLvgGfPCqpfSvaG.kq 80
+++++Lf+Gi l l+ g ++ ++ase ++ +++ ++ + gDi++i+ k ++e +Dl++gG PC++ S+ ++
tr|B8JLQ7|B8JLQ7_DANRE 575 IRVLSLFDGIATGLLVLKDLGiqVDRYVASEVCEDSITVGMVRHFerITYVGDIRNITRKHIQEwGpFDLVIGGSPCNDLSIVNpAR 661
5899*****************999999999999998887666665578899*********9997647**************987369 PP
--TTSGGGHHHHHHHHHHHHH-.......-SEEEEEEEGGGGGGCCS CS
DNA_methylase 81 kgfedtrgtLffeiiriikekk.......PkvfllENVkgLlkhdkg 120
kg + g Lffe+ r++ e + P + l+ENV + +dk+
tr|B8JLQ7|B8JLQ7_DANRE 662 KGLFEGTGRLFFEFYRLLHEARpkegddrPFFWLFENVVAMGVSDKK 708
*********************95555555558899999888766664 PP
== domain 2 score: 14.4 bits; conditional E-value: 1.3e-05
-B-TTS---EEEETTEEE--T.TTGGG--B-BHHHHHHHHT--TT-----SBH..HHHHHHHTS--HHHHHHHHHH CS
DNA_methylase 259 klekelaeagklqknkerfkpviekkriRrLtprEaarlqGfPddfefgskks..aaykqiGnsVpvpvieaiake 332
k+++ ++++++ + k + pv+ ++++ L E+ r+ GfP ++ s+ s a+ +++G s +vpvi++++
tr|B8JLQ7|B8JLQ7_DANRE 770 KVRTITTRSNSIKQGKDQHYPVYMNNKEDILWCTEMERVFGFPVHYTDVSNMSrlARQRLLGRSWSVPVIRHLFAP 845
33444444444444444445799************************999999889999*************9875 PP
>> tr|F1R1K5|F1R1K5_DANRE DNA (cytosine-5-)-methyltransferase 3 alpha b OS=Danio rerio OX=7955 GN=dnmt3ab PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 48.5 0.0 5.6e-16 1.1e-12 1 120 [. 698 831 .. 698 846 .. 0.89
2 ! 11.2 0.0 0.00013 0.25 265 332 .. 899 968 .. 852 971 .. 0.75
Alignments for each domain:
== domain 1 score: 48.5 bits; conditional E-value: 5.6e-16
-EEEEES-TT-HHHHHHHHTT..-EEEEEEE--TTTHHHHHHH-...-SEEEES-TTTS-GS--...-SEEEE---GGGTECTS.EE CS
DNA_methylase 1 lkfidLfaGiGGfrlgleaag..fecvaaseidkkaaktYeanfk..kvsigDitkidkkklpe.d.iDlLvgGfPCqpfSvaG.kq 80
+++++Lf+Gi l l++ g +e ++ase ++ +++ +++ + gD+++++ k+++e +Dl++gG PC++ S+ ++
tr|F1R1K5|F1R1K5_DANRE 698 IRVLSLFDGIATGLLVLRELGiqVERYVASEVCEDSITVGIVRHQgrIMYVGDVRQLTRKNIQEwGpFDLVIGGSPCNDLSIVNpAR 784
5899*****************99999*************999999999***************8747**************98736* PP
--TTSGGGHHHHHHHHHHHHH-.......-SEEEEEEEGGGGGGCCS CS
DNA_methylase 81 kgfedtrgtLffeiiriikekk.......PkvfllENVkgLlkhdkg 120
kg + g Lffe+ r++ e + P + l+ENV + +dk+
tr|F1R1K5|F1R1K5_DANRE 785 KGLYEGTGRLFFEFYRLLHEARpkegdtrPFFWLFENVVAMGVSDKR 831
********************995555555568899999888777665 PP
== domain 2 score: 11.2 bits; conditional E-value: 0.00013
---EEEETTEEE--T.TTGGG--B-BHHHHHHHHT--TT-----SBH..HHHHHHHTS--HHHHHHHHHH CS
DNA_methylase 265 aeagklqknkerfkpviekkriRrLtprEaarlqGfPddfefgskks..aaykqiGnsVpvpvieaiake 332
+++++ + k + pv + ++ L E+ r+ GfP ++ s+ s a+ +++G s +vpvi++++
tr|F1R1K5|F1R1K5_DANRE 899 TRSNSIKQGKDQHFPVFMNDKEDILWCTEMERVFGFPVHYTDVSNMSrlARQRLLGRSWSVPVIRHLFAP 968
222222222222235788888889999**************999999889999*************9875 PP
>> tr|E7F6H4|E7F6H4_DANRE DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a OS=Danio rerio OX=7955 GN=dnmt3ba PE=
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -3.8 0.2 4.5 9e+03 234 267 .. 778 809 .. 731 845 .. 0.38
2 ! 49.6 0.0 2.6e-16 5.1e-13 1 120 [. 1222 1355 .. 1222 1370 .. 0.88
3 ! 9.1 0.0 0.00052 1 273 331 .. 1431 1491 .. 1385 1495 .. 0.76
Alignments for each domain:
== domain 1 score: -3.8 bits; conditional E-value: 4.5
TS--B--TTS...-B----S-STT-.......-B-TTS--- CS
DNA_methylase 234 srnridkveelkglsatrrksgrge.......klekelaea 267
++++ +++ +t++ s + +lek + ++
tr|E7F6H4|E7F6H4_DANRE 778 MKKSRRSTS------ETVQHS---NavkpcvvRLEKITSQR 809
111111111......111111...01112222222333333 PP
== domain 2 score: 49.6 bits; conditional E-value: 2.6e-16
-EEEEES-TT-HHHHHHHHTT..-EEEEEEE--TTTHHHHHHH-...-SEEEES-TTTS-GS--...-SEEEE---GGGTECTS. CS
DNA_methylase 1 lkfidLfaGiGGfrlgleaag..fecvaaseidkkaaktYeanfk..kvsigDitkidkkklpe.d.iDlLvgGfPCqpfSvaG. 78
+++++Lf+Gi l l+ g e ++asei ++ +++ +++ + +D+++i+ k l+e +DlL+gG PC++ S
tr|E7F6H4|E7F6H4_DANRE 1222 IRVLSLFDGIATGYLVLKDLGfkLERYIASEICEDSIAVGMVKHEgkIEYVKDVRTITRKHLAEwGpFDLLIGGSPCNDLSMVNp 1306
5899*****************777889********9998888888778889*********9997647**************8762 PP
EE--TTSGGGHHHHHHHHHHHHH-.......-SEEEEEEEGGGGGGCCS CS
DNA_methylase 79 kqkgfedtrgtLffeiiriikekk.......PkvfllENVkgLlkhdkg 120
++kg + g Lffe+ r++ + P + l+ENV + hdk
tr|E7F6H4|E7F6H4_DANRE 1307 ARKGLFEGTGRLFFEYYRMLTMMRpkedddrPFFWLFENVVAMSAHDKA 1355
69******************999855555556699***********986 PP
== domain 3 score: 9.1 bits; conditional E-value: 0.00052
TEEE--T.TTGGG--B-BHHHHHHHHT--TT-----SBH..HHHHHHHTS--HHHHHHHHH CS
DNA_methylase 273 nkerfkpviekkriRrLtprEaarlqGfPddfefgskks..aaykqiGnsVpvpvieaiak 331
k pv + ++ L E+ ++ GfP+ ++ + ++ k++G s +vpvi++++
tr|E7F6H4|E7F6H4_DANRE 1431 GKTGPLPVTMNGKEDYLWCTEMEKIFGFPKHYTDVNNMGrgQRQKVLGRSWSVPVIRHLFA 1491
33333347777777788899************988777778*****************986 PP
>> tr|A3QJU7|A3QJU7_DANRE DNA (cytosine-5-)-methyltransferase beta, duplicate b.3 OS=Danio rerio OX=7955 GN=dnmt3bb.3 P
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 46.0 0.0 3.2e-15 6.3e-12 2 112 .. 1013 1137 .. 1012 1152 .. 0.87
2 ! 8.1 0.0 0.001 2.1 280 331 .. 1229 1282 .. 1173 1286 .. 0.77
Alignments for each domain:
== domain 1 score: 46.0 bits; conditional E-value: 3.2e-15
EEEEES-TT-HHHHHHHHTT..-EEEEEEE--TTTHHHHHHH-...-SEEEES-TTTS-GS--...-SEEEE---GGGTECTSE. CS
DNA_methylase 2 kfidLfaGiGGfrlgleaag..fecvaaseidkkaaktYeanfk..kvsigDitkidkkklpe.d.iDlLvgGfPCqpfSvaGk. 79
++++Lf+Gi l l+ g +e ++ase d++ +++ n++ + D++ki+ k + + +DlL+gG PC++
tr|A3QJU7|A3QJU7_DANRE 1013 RVLSLFDGIATGYLVLRDLGfkVEKYVASEVDEESVTISMVNHEgkITYVDDVKKITRKHIDKwGpFDLLIGGSPCNDLCTVNPg 1097
899*****************888899*****************99888899********9998747************9977544 PP
E--TTSGGGHHHHHHHHHHHHH-.......-SEEEEEEEG CS
DNA_methylase 80 qkgfedtrgtLffeiiriikekk.......PkvfllENVk 112
+kg + +g Lffe+ r+++ k P + l+ENV
tr|A3QJU7|A3QJU7_DANRE 1098 RKGLFEGSGRLFFEYYRLLNVLKpkeddprPFFWLFENVV 1137
*******************999944455445577888885 PP
== domain 2 score: 8.1 bits; conditional E-value: 0.001
.TTGGG--B-BHHHHHHHHT--TT-----SBH..HHHHHHHTS--HHHHHHHHH CS
DNA_methylase 280 viekkriRrLtprEaarlqGfPddfefgskks..aaykqiGnsVpvpvieaiak 331
++ + + L E ++ GfP+ ++ + ++ +++G s +vpvi++++
tr|A3QJU7|A3QJU7_DANRE 1229 IVMNGKDDSLWITEIEKIFGFPKHYTDVKNLGrmQRQRVLGKSWSVPVIRHLLA 1282
6666677778899************9888877789999************9986 PP
>> sp|A3KP85|ETKMT_DANRE Electron transfer flavoprotein beta subunit lysine methyltransferase OS=Danio rerio OX=7955 GN
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 13.6 0.0 2.3e-05 0.046 2 42 .. 110 150 .. 109 163 .. 0.90
Alignments for each domain:
== domain 1 score: 13.6 bits; conditional E-value: 2.3e-05
EEEEES-TT-HHHHHHHHTT-EEEEEEE--TTTHHHHHHH- CS
DNA_methylase 2 kfidLfaGiGGfrlgleaagfecvaaseidkkaaktYeanf 42
k++dL +G+G+ +++ + g +cv+a++id+ aa ++n
sp|A3KP85|ETKMT_DANRE 110 KVLDLGCGCGASAIAARLSGASCVVANDIDPIAAIATKMNC 150
789****************************9988777765 PP
>> tr|E9QCX1|E9QCX1_DANRE Methyltransferase-like 5 OS=Danio rerio OX=7955 GN=mettl5 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.9 0.0 3.8e-05 0.075 3 69 .. 52 124 .. 51 126 .. 0.80
Alignments for each domain:
== domain 1 score: 12.9 bits; conditional E-value: 3.8e-05
EEEES-TT-HHHHHHHHTT-EEEEEEE--TTTHHHHHHH-...-SEEEES-TTTS-....GS--.-SEEEE-- CS
DNA_methylase 3 fidLfaGiGGfrlgleaagfecvaaseidkkaaktYeanfk..kvsigDitkidkk....klpediDlLvgGf 69
+ dL +G+G +++g + ++ +id++a ++++ n + + ++ D+ + d ++++++D ++ +
tr|E9QCX1|E9QCX1_DANRE 52 VADLGCGCGVLSIGAAVLDAGLCVGFDIDEDALDIFRGNVEefELPNIDVVQCDVCsigsSYAKKFDTVIMNP 124
579**************************************67666666666665466665555677766655 PP
>> sp|Q0P466|TYW2_DANRE tRNA wybutosine-synthesizing protein 2 homolog OS=Danio rerio OX=7955 GN=trmt12 PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.6 0.0 9.4e-05 0.18 3 53 .. 221 280 .. 220 291 .. 0.76
Alignments for each domain:
== domain 1 score: 11.6 bits; conditional E-value: 9.4e-05
EEEES-TT-HHHHH.HHHTT-EEEEEEE--TTTHHHHHHH-.........-SEEEES-TT CS
DNA_methylase 3 fidLfaGiGGfrlg.leaagfecvaaseidkkaaktYeanfk........kvsigDitki 53
++dL aGiG f+l l a+ +v a e++++a++ +++n + v++gD +++
sp|Q0P466|TYW2_DANRE 221 VVDLYAGIGYFTLPyLVHANAAHVHACEWNPDAVAALQRNLEingvsnrcTVHQGDNRQL 280
89***********8567888********************98766444444444444444 PP
>> tr|F6NL10|F6NL10_DANRE R3H domain-containing 4 OS=Danio rerio OX=7955 GN=r3hdm4 PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.8 1.2 8.3e-05 0.16 171 295 .. 18 140 .. 7 150 .. 0.73
Alignments for each domain:
== domain 1 score: 11.8 bits; conditional E-value: 8.3e-05
-----SS---GGG.....TSGGGTTS-EEBTTTB--GGGSSSTT-EE--.......S---HHHTS--B--TTS...-B----S-STT CS
DNA_methylase 171 vkvkefrfpkkkdleasktlrdlleekseldeektalsdklvekeekikkttkaseegypkelsrnridkveelkglsatrrksgrg 257
++ k+++f +++ +s+ + + +++ks+ +e+t++ d+l+e++e +k+ + e++ p ++ + ++++++++s+ + +sg+
tr|F6NL10|F6NL10_DANRE 18 SPAKKKQFFINQAIRNSDLIPRAKGKKSQRRQENTRFLDNLLERDECSKEDGEGHETASP-SIFTEACTNGNYMEYWSDFMNRSGEE 103
455666666666688999999999999999******************988777777777.9999999999999****999999986 PP
-.......-B-TTS---EEEETTEEE--T.TTGGG--B-BHHHHH CS
DNA_methylase 258 e.......klekelaeagklqknkerfkpviekkriRrLtprEaa 295
+ + ea+++++nk++ + + + +++ +E++
tr|F6NL10|F6NL10_DANRE 104 QerllallE-----EEAQRTHSNKSH---KDQREVNPAFSAQECF 140
655444222.....222333333332...2345677777777776 PP
>> tr|Q5RHJ0|Q5RHJ0_DANRE Si:ch211-241j12.3 OS=Danio rerio OX=7955 GN=si:ch211-241j12.3 PE=3 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 0.8 5.9 0.18 3.5e+02 188 276 .. 933 1053 .. 897 1069 .. 0.52
2 ? 7.2 0.0 0.002 4 185 275 .. 1209 1301 .. 1176 1334 .. 0.82
Alignments for each domain:
== domain 1 score: 0.8 bits; conditional E-value: 0.18
.TSGGGTTS-EEBTTTB--GGGSSSTT-EE--.......S---HHHTS--..................................B CS
DNA_methylase 188 ktlrdlleekseldeektalsdklvekeekikkttkaseegypkelsrnr..................................i 238
+++r+ e + ++ ee+++++++ e+ e+i++ ++++ + + + r++ +
tr|Q5RHJ0|Q5RHJ0_DANRE 933 DEIRQCTETEDQTLEERWQWTENENERLEEIRQCSETKDPTLE--VLRRCtetedqtlekmqqctktedkrleeiqcneiedqtL 1015
4444444443335555555555555555555544444433333..3333223333332222222222222222222222333337 PP
--TTS...-B----S-STT--B-TTS---EEEETTEEE CS
DNA_methylase 239 dkveelkglsatrrksgrgeklekelaeagklqknker 276
+++ e+ ++s+ ++ks++g+++++++ ++++ ++++e
tr|Q5RHJ0|Q5RHJ0_DANRE 1016 EEITEVGKKSSEVEKSRSGRVIRCSAMKNSSQWRDEEM 1053
77777777777777777777777777777777766664 PP
== domain 2 score: 7.2 bits; conditional E-value: 0.002
....TSGGGTTS-EE..BTTTB--GGGSSSTT-EE--.......S---HHHTS--B--TTS...-B----S-STT--B-TTS--- CS
DNA_methylase 185 easktlrdlleekse..ldeektalsdklvekeekikkttkaseegypkelsrnridkveelkglsatrrksgrgeklekelaea 267
++++ dl+e++s ++e+++ ++ + e++ ++++++ + +++ +++ + +r ++++e+++ls+t + g+ ++++ ++++
tr|Q5RHJ0|Q5RHJ0_DANRE 1209 SEQTHTGDLEESSSTseHTEDDEDYEGDEGEEHTQSRPASLHMQNNNNNTAVVQRSEQSQEMQTLSSTADAGGFMRTCTSTVQQI 1293
45556677777766677***************************999997777779*****************998777777777 PP
EEEETTEE CS
DNA_methylase 268 gklqknke 275
++ + +
tr|Q5RHJ0|Q5RHJ0_DANRE 1294 STATTQMT 1301
66665555 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (335 nodes)
Target sequences: 25687 (13798380 residues searched)
Passed MSV filter: 2366 (0.0921088); expected 513.7 (0.02)
Passed bias filter: 861 (0.0335189); expected 513.7 (0.02)
Passed Vit filter: 110 (0.00428232); expected 25.7 (0.001)
Passed Fwd filter: 20 (0.000778604); expected 0.3 (1e-05)
Initial search space (Z): 25687 [actual number of targets]
Domain search space (domZ): 13 [number of targets reported over threshold]
# CPU time: 0.68u 0.03s 00:00:00.71 Elapsed: 00:00:00.24
# Mc/sec: 19260.24
//
[ok]