# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/DREV.hmm.txt # target sequence database: proteomes/Caenorhabditis_elegans.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: DREV [M=265] Accession: PF05219.11 Description: DREV methyltransferase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2.4e-139 463.0 0.2 2.8e-139 462.8 0.2 1.0 1 tr|Q22123|Q22123_CAEEL Uncharacterized protein OS=Caenorhabd 0.00026 20.3 0.1 0.00071 18.9 0.0 1.8 2 tr|Q22993|Q22993_CAEEL Phosphoethanolamine MethylTransferase 0.0015 17.9 0.1 0.0018 17.6 0.1 1.1 1 tr|Q9GZF8|Q9GZF8_CAEEL PRotein arginine MethylTransferase OS ------ inclusion threshold ------ 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 sp|Q09522|DIM1_CAEEL Probable dimethyladenosine transferas Domain annotation for each sequence (and alignments): >> tr|Q22123|Q22123_CAEEL Uncharacterized protein OS=Caenorhabditis elegans OX=6239 GN=CELE_T03G11.6 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 462.8 0.2 5.6e-143 2.8e-139 1 265 [] 16 281 .. 16 281 .. 0.99 Alignments for each domain: == domain 1 score: 462.8 bits; conditional E-value: 5.6e-143 DREV 1 WyvlnrelseslqalfvaslpdaetqsflenskklsanlfiqlyhalassilslfmsktdinGllgrGsmfvlseeqfrkllaieke 87 Wy+++++ls+++q+lf+aslpd+etq+fl+ns+k+++n+f+q++++l+++ils+++sktdinG++g+G+mf++se+qf+k+laieke tr|Q22123|Q22123_CAEEL 16 WYQPETSLSDVAQNLFAASLPDGETQQFLDNSNKIASNFFWQTVRNLGVMILSTIYSKTDINGMTGFGNMFLFSENQFAKFLAIEKE 102 *************************************************************************************** PP DREV 88 spasdqedkklldlGaGdGeitkrvaptfeevyatelsetmrdrlkkkkynvlsalelqetdvkldlilclnlldrcfdplklledi 174 s++s +dkk+ldlGaG+G+it++++p+fe+vyatels++mr+rl++k+ynvlsale++etdvk+dl++++nlldr+++p+kll+d+ tr|Q22123|Q22123_CAEEL 103 SWNS--TDKKVLDLGAGNGDITEHMRPFFEHVYATELSSKMRNRLSWKGYNVLSALEWAETDVKFDLVTAFNLLDRHYSPGKLLNDL 187 ****..********************************************************************************* PP DREV 175 rs.alepngrvivalvlPvshyvetnt.gksekpsellevkGrsyeeevarli.evlkkagfeveaftrlPylceGdlnnsfyyldd 258 ++ a+++n++viv+lvlPvshyve+n+ g+s++p+++l+v+Gr+y+++v+++i +v+k+a+fev+++trlPylceGd+nns+yyl+d tr|Q22123|Q22123_CAEEL 188 WNvARRSNCNVIVSLVLPVSHYVEFNPnGRSTRPDNYLNVAGRTYADHVHHMIvNVFKPANFEVLRWTRLPYLCEGDMNNSAYYLPD 274 **89999*********************************************99********************************* PP DREV 259 aifvlkk 265 aif+lk+ tr|Q22123|Q22123_CAEEL 275 AIFLLKP 281 *****97 PP >> tr|Q22993|Q22993_CAEEL Phosphoethanolamine MethylTransferase OS=Caenorhabditis elegans OX=6239 GN=pmt-2 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.0 0.1 0.68 3.4e+03 138 176 .. 51 89 .. 47 103 .. 0.70 2 ! 18.9 0.0 1.4e-07 0.00071 56 188 .. 187 328 .. 151 367 .. 0.79 Alignments for each domain: == domain 1 score: -3.0 bits; conditional E-value: 0.68 DREV 138 nvlsalelqetdvkldlilclnlldrcfdplklledirs 176 +v + le t + d++ n l + ll d + tr|Q22993|Q22993_CAEEL 51 QVHTSLEQLSTIRNADVLIFNNALSQIITNADLLTDFLK 89 566777766677888888888999999999999998654 PP == domain 2 score: 18.9 bits; conditional E-value: 1.4e-07 DREV 56 msktdinGllg.rGsmfvlseeqfrkllaiekespasdqedkklldlGaGdGeitkrvaptfe.evyatelsetmr....drl.... 132 +++t i+ +G +s+ + l+i k + + +++ld+G G G +++va+ f +v+ +ls++m +rl tr|Q22993|Q22993_CAEEL 187 YTNTGIDAYEWmFGVN-FISPGGYDENLKIIKR-FGDFKPGQTMLDIGVGIGGGARQVADEFGvHVHGIDLSSNMLaialERLheek 271 5555555554313433.4577777777777633.223245689***************99985489999999999533335662222 PP DREV 133 .kkkkynvlsalelqetdvkldlilclnlldrcfdplklledirsalepngrvival 188 ++ ky + al +q d +d + + + + d+ kl+ i++al+p g+v++++ tr|Q22993|Q22993_CAEEL 272 dSRVKYSITDALVYQFEDNSFDYVFSRDCIQHIPDTEKLFSRIYKALKPGGKVLITM 328 2456899999999****************************************9975 PP >> tr|Q9GZF8|Q9GZF8_CAEEL PRotein arginine MethylTransferase OS=Caenorhabditis elegans OX=6239 GN=prmt-4 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.6 0.1 3.5e-07 0.0018 92 179 .. 35 129 .. 20 135 .. 0.78 Alignments for each domain: == domain 1 score: 17.6 bits; conditional E-value: 3.5e-07 DREV 92 dqedkklldlGaGdG.eitkrvaptfeevyatelsetmrdrlkkk.......kynvlsalelqetdvkldlilclnlldrcfdplkl 170 + +dkk+ld+G G+G + t ++ +v + s++m+++ k + ++ l + ++q d k+ + +++ +l +d +l tr|Q9GZF8|Q9GZF8_CAEEL 35 NLKDKKVLDIGCGNGlNSTTFLQWGARKVVGFDNSQEMIENCKNLhksseqsSFHHLNVTDFQ-LDEKFHVATAVFVLQYVHDKEEL 120 4699***********4456667777889**********9876543111222268889999999.889999**************999 PP DREV 171 ledirsale 179 + ir++ e tr|Q9GZF8|Q9GZF8_CAEEL 121 RKAIRLIWE 129 999998765 PP >> sp|Q09522|DIM1_CAEEL Probable dimethyladenosine transferase OS=Caenorhabditis elegans OX=6239 GN=E02H1.1 PE=3 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.0 0.0 4.5e-06 0.023 93 135 .. 49 91 .. 24 106 .. 0.87 Alignments for each domain: == domain 1 score: 14.0 bits; conditional E-value: 4.5e-06 DREV 93 qedkklldlGaGdGeitkrvaptfeevyatelsetmrdrlkkk 135 + + ++l++G G G++t ++ + + v a e+ +m+ +kk+ sp|Q09522|DIM1_CAEEL 49 KATDTVLEVGPGTGNLTVKMLEVAKTVIACEIDPRMIAEVKKR 91 56889*********************************99986 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (265 nodes) Target sequences: 20008 (8229220 residues searched) Passed MSV filter: 463 (0.0231407); expected 400.2 (0.02) Passed bias filter: 287 (0.0143443); expected 400.2 (0.02) Passed Vit filter: 23 (0.00114954); expected 20.0 (0.001) Passed Fwd filter: 4 (0.00019992); expected 0.2 (1e-05) Initial search space (Z): 20008 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.15u 0.01s 00:00:00.16 Elapsed: 00:00:00.06 # Mc/sec: 36345.72 // [ok]