# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/DREV.hmm.txt # target sequence database: proteomes/Ciona_intestinalis.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: DREV [M=265] Accession: PF05219.11 Description: DREV methyltransferase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.1e-05 22.7 0.0 5e-05 22.4 0.0 1.1 1 tr|H2XS49|H2XS49_CIOIN Uncharacterized protein OS=Ciona inte 5.1e-05 22.4 0.0 9.8e-05 21.5 0.0 1.4 2 tr|F6RBS2|F6RBS2_CIOIN Uncharacterized protein OS=Ciona inte 8.3e-05 21.7 0.0 0.00017 20.7 0.0 1.6 2 tr|F7B757|F7B757_CIOIN Uncharacterized protein OS=Ciona inte 0.00021 20.4 0.0 0.00047 19.2 0.0 1.6 2 tr|H2XKR4|H2XKR4_CIOIN Uncharacterized protein OS=Ciona inte 0.0088 15.1 0.0 0.015 14.4 0.0 1.3 1 tr|H2XVH5|H2XVH5_CIOIN Uncharacterized protein OS=Ciona inte ------ inclusion threshold ------ 0.012 14.6 0.0 0.021 13.9 0.0 1.3 1 tr|H2XWY6|H2XWY6_CIOIN Uncharacterized protein OS=Ciona inte 0.02 13.9 0.0 0.037 13.0 0.0 1.4 1 tr|F7B763|F7B763_CIOIN Uncharacterized protein OS=Ciona inte 0.021 13.8 0.0 0.029 13.4 0.0 1.3 1 tr|F6Q929|F6Q929_CIOIN uncharacterized protein LOC100181888 0.022 13.7 0.1 0.067 12.2 0.0 1.8 2 tr|F6X5I5|F6X5I5_CIOIN Uncharacterized protein OS=Ciona inte 0.045 12.7 0.0 0.075 12.0 0.0 1.3 1 tr|F6UIG7|F6UIG7_CIOIN Uncharacterized protein OS=Ciona inte 0.057 12.4 0.0 0.077 12.0 0.0 1.2 1 tr|F7BDM8|F7BDM8_CIOIN Uncharacterized protein OS=Ciona inte 0.099 11.6 0.0 0.14 11.2 0.0 1.2 1 tr|H2XQ96|H2XQ96_CIOIN Uncharacterized protein OS=Ciona inte Domain annotation for each sequence (and alignments): >> tr|H2XS49|H2XS49_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.4 0.0 3.6e-08 5e-05 94 205 .. 42 160 .. 29 201 .. 0.71 Alignments for each domain: == domain 1 score: 22.4 bits; conditional E-value: 3.6e-08 DREV 94 edkklldlGaGdGeitkrvaptfeevyatelsetm......rdrlkkkkynvlsalelqetdvkldlilclnlldrcfdplklledi 174 + lld+G G G+ k+ ap+f++v a + se+ ++++ + y+v a +l dv d+i++ l d k+ e++ tr|H2XS49|H2XS49_CIOIN 42 KLDFLLDVGCGGGQAVKIFAPYFDKVLAIDPSENQleearsQNKFAHVTYEVGLAEKLPCNDVSVDVITVASALHW-LDRQKFYEEV 127 44568*************************9986511111133444445555555557778*******98777754.4557999*** PP DREV 175 rsalepngrvivalvlP.v.shyvetntgksek 205 +l+p gr i v + + y e + k+++ tr|H2XS49|H2XS49_CIOIN 128 DRVLKPGGREIYLQVCNkYaQIYNEIKYAKKLR 160 ******999886655431312355555555555 PP >> tr|F6RBS2|F6RBS2_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.5 0.0 7e-08 9.8e-05 81 183 .. 29 135 .. 23 164 .. 0.73 2 ? -3.2 0.0 2.4 3.3e+03 126 165 .. 224 265 .. 209 267 .. 0.62 Alignments for each domain: == domain 1 score: 21.5 bits; conditional E-value: 7e-08 DREV 81 llaiekespasdqedkklldlGaGdGeitkrvaptfeevyatelse......tmrdrlkkkkynvlsalelqetdvkldlilclnll 161 ++ ++k++ + + ++ + +d+G G G+ t++ ap+f++v at+ s +m+++++ y+ +a +++ d ldl+++ l tr|F6RBS2|F6RBS2_CIOIN 29 FV-VNKMRSKNKTDSSEKVDVGCGSGQATNIFAPYFKKVLATDPSVnqlehaRMQNKFDNVSYEEGTAENIKVEDCSLDLLVAGCAL 114 44.5556666667778889************************98622222257777777777777777788888999999888777 PP DREV 162 drcfdplklledirsalepngr 183 fd k+l++ +l+p g tr|F6RBS2|F6RBS2_CIOIN 115 PY-FDHPKFLQEADRVLKPGGY 135 64.5555788888888888664 PP == domain 2 score: -3.2 bits; conditional E-value: 2.4 DREV 126 etmrdrlkkkkynvlsalelqetdvkldlil..clnlldrcf 165 +m + + + n ls e e +ld+ + ++l rc+ tr|F6RBS2|F6RBS2_CIOIN 224 YEMYMKKQAVGLNNLSDKEQMEKLKQLDVAEhcADEVLSRCY 265 456666666677777777766666667765321335667766 PP >> tr|F7B757|F7B757_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.7 0.0 1.2e-07 0.00017 94 186 .. 38 135 .. 25 176 .. 0.80 2 ? -3.3 0.0 2.5 3.4e+03 141 160 .. 255 274 .. 239 276 .. 0.67 Alignments for each domain: == domain 1 score: 20.7 bits; conditional E-value: 1.2e-07 DREV 94 edkklldlGaGdGeitkrvaptfeevyatelsetmrd.rlkkkkynvlsale.lqe....tdvkldlilclnlldrcfdplklledi 174 + lld+G G G+ ++ ap+f+ev a + se+ ++ ++ k+ ++ + ++e dv d+i++ + + k+ e++ tr|F7B757|F7B757_CIOIN 38 KLDFLLDVGCGGGQSVNIFAPYFHEVLAIDPSENQIKeARSQNKFAHVTYKQgIAEklpcDDVSVDVITVGTAIHWLDR-PKFYEEV 123 44568***************************976651456677877765544444222279******86555544433.4899*** PP DREV 175 rsalepngrviv 186 +l+pngr i+ tr|F7B757|F7B757_CIOIN 124 TRVLKPNGRLII 135 *********997 PP == domain 2 score: -3.3 bits; conditional E-value: 2.5 DREV 141 salelqetdvkldlilclnl 160 + e++++dvk++++ + + tr|F7B757|F7B757_CIOIN 255 GCTEMENSDVKMQVVFNFFV 274 45677788888888877665 PP >> tr|H2XKR4|H2XKR4_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.2 0.0 3.4e-07 0.00047 92 156 .. 43 113 .. 29 142 .. 0.71 2 ? -1.5 0.0 0.73 1e+03 15 46 .. 125 156 .. 117 184 .. 0.78 Alignments for each domain: == domain 1 score: 19.2 bits; conditional E-value: 3.4e-07 DREV 92 dqedkklldlGaGdGeitkrvaptfeevyatelsetmrdrlk.kkkynvlsale.lqet....dvkldlil 156 +++ + lld+G G G+ t++ ap+f+ev a ++se+ + k + k ++ + ++et dv d+i+ tr|H2XKR4|H2XKR4_CIOIN 43 GKKLNFLLDVGCGGGQTTNIFAPYFHEVLAIDVSENQLKEAKsQNKLAHVTYKQgFAETlpcdDVSADIIT 113 5666779***************************9754443303333333333335544333356666665 PP == domain 2 score: -1.5 bits; conditional E-value: 0.73 DREV 15 lfvaslpdaetqsflenskklsanlfiqlyha 46 +f + +++++ s len ++s+n ++++ + tr|H2XKR4|H2XKR4_CIOIN 125 KFYNEQLETKNNSKLENIYRISSNKYLKILDE 156 56667777777888888888888888877654 PP >> tr|H2XVH5|H2XVH5_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.4 0.0 1e-05 0.015 97 185 .. 7 100 .. 1 104 [. 0.71 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 1e-05 DREV 97 klldlGaGdGeitkrvaptfeevyatelsetmrdr.lkkkkynvlsale.lqe....tdvkldlilclnlldrcfdplklledirsa 177 lld+G G G+ ++ ap+f+ev a + se+ ++ ++ k+ ++ ++e dv d+i + + fd k+ e+ + tr|H2XVH5|H2XVH5_CIOIN 7 FLLDVGCGGGQSVNIFAPYFHEVLAIDPSENQIKEaRSQNKFAHVTYKAgFAEklpcDDVSVDVIIAGASV-HWFDRQKFYEEADRV 92 59**************************9976654145666766665433554222258888888876554.456677777777777 PP DREV 178 lepngrvi 185 l+p gr + tr|H2XVH5|H2XVH5_CIOIN 93 LKPGGRLV 100 77777766 PP >> tr|H2XWY6|H2XWY6_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.0 1.5e-05 0.021 93 182 .. 75 173 .. 60 180 .. 0.78 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 1.5e-05 DREV 93 qedkklldlGaGdGeitkrvapt.fee.vyatelsetmrdrlkkkk.ynvlsale......lqetdvkldlilclnlldrcfdplkl 170 + d +ldl +G G k +++ f+ + a e+ e m ++ +kk+ y+ l++ l d +d+i+c + r + + tr|H2XWY6|H2XWY6_CIOIN 75 RSDFSILDLASGTGRCGKALRDSgFKCiIDALEANEAMNQKASKKGiYRNLTVHVvtpttkLPIEDESYDVIVCTGGFSRTHIQSEC 161 45789**************998624445789***********99976777766541000024445789******************* PP DREV 171 ledirsalepng 182 ++d+ +l+p g tr|H2XWY6|H2XWY6_CIOIN 162 IKDVVRVLKPGG 173 ******999966 PP >> tr|F7B763|F7B763_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.0 2.6e-05 0.037 94 157 .. 38 107 .. 25 137 .. 0.65 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 2.6e-05 DREV 94 edkklldlGaGdGeitkrvaptfeevyatelset.mrdrlkkkkynvlsale.lqe....tdvkldlilc 157 + lld+G G G+ ++ ap+f+ev a + se+ +++ ++ k+ ++ + ++e +v d+i++ tr|F7B763|F7B763_CIOIN 38 KIDFLLDVGCGGGQSVNIFAPYFHEVLAIDPSENqLKEARSQNKFAHVTYKQgIAEklpcDNVSVDVITS 107 45569*************************9986255556667777666544333311114566666665 PP >> tr|F6Q929|F6Q929_CIOIN uncharacterized protein LOC100181888 OS=Ciona intestinalis OX=7719 GN=LOC100181888 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.4 0.0 2.1e-05 0.029 90 188 .. 61 168 .. 19 194 .. 0.82 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 2.1e-05 DREV 90 asdqedkklldlGaGdG..eitkrvaptfeevyatelsetmrdrlkkkk.y.....nvlsale.lqetdvkldlilclnlldrcfdp 167 + ++e+ klldlGaG G + r + ++ ++ a + s +m + k+ y ++l+ + l d +++++++ + ++ tr|F6Q929|F6Q929_CIOIN 61 DKQKENFKLLDLGAGTGlsGAALRRSGFLGNISALDGSAEMLKVATEKGiYsdsteHILTSSNpLPYPDHSFEMVVSVATFTKHLME 147 3456788*********933456677889*************988776652433333577777778999******************9 PP DREV 168 lklledirsalepngrvival 188 le++ +l+p++ +i+++ tr|F6Q929|F6Q929_CIOIN 148 PDCLEEVLRVLKPHSYMIITI 168 *************99999876 PP >> tr|F6X5I5|F6X5I5_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=3 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 4.8e-05 0.067 92 138 .. 54 101 .. 41 111 .. 0.78 2 ? -3.0 0.0 2 2.8e+03 234 263 .. 273 302 .. 248 303 .. 0.77 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 4.8e-05 DREV 92 dqedkklldlGaGdGeitkrvapt.feevyatelsetmrdrlkkkkyn 138 +dk +ld+GaG G ++ a+ ++vya e+s+ ++ k + n tr|F6X5I5|F6X5I5_CIOIN 54 SLKDKVVLDVGAGTGILSCFCAQAgAKKVYAIEASNIAKQAKKVVELN 101 47999*************9987762678*******9877666555555 PP == domain 2 score: -3.0 bits; conditional E-value: 2 DREV 234 eveaftrlPylceGdlnnsfyylddaifvl 263 + Py e ++s yl++ + v+ tr|F6X5I5|F6X5I5_CIOIN 273 AMSNLSTSPYKPETHWKQSLLYLNNEVQVV 302 455667789999999999999999888775 PP >> tr|F6UIG7|F6UIG7_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=3 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.0 5.4e-05 0.075 92 134 .. 155 197 .. 124 203 .. 0.83 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 5.4e-05 DREV 92 dqedkklldlGaGdGeitk.rvaptfeevyatelsetmrdrlkk 134 +++dk +ld+GaG G ++ ++ +vya e+s tm ++ kk tr|F6UIG7|F6UIG7_CIOIN 155 NFRDKVVLDVGAGSGILSFfAMQAGARKVYAVEAS-TMAEHTKK 197 578999**********99636899999******98.56665555 PP >> tr|F7BDM8|F7BDM8_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=3 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.0 5.5e-05 0.077 56 149 .. 55 142 .. 32 185 .. 0.79 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 5.5e-05 DREV 56 msktdinGllgrGsmfvlseeqfrkllaiekespasdqedkklldlGaGdGeitkrvaptfeevyatelsetmrdrlkkkkynvlsa 142 ++k +i+G++++ f + kll i ++ dq +k+l +l aGdG+++++ + f vy+t r +l++ ++++s tr|F7BDM8|F7BDM8_CIOIN 55 FTKKEIEGFIQK--SFTGDAKPHGKLLSIPEKGVPIDQLQKELNELKAGDGNLSENGR-LFAYVYTTHG---PRFQLQQEAFKMFSD 135 567788888775..4777788889******999999******************9865.7899**9975...588999999999998 PP DREV 143 lelqetd 149 l++++ tr|F7BDM8|F7BDM8_CIOIN 136 FSLAKAN 142 8887543 PP >> tr|H2XQ96|H2XQ96_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 9.8e-05 0.14 97 156 .. 6 71 .. 1 86 [. 0.68 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 9.8e-05 DREV 97 klldlGaGdGeitkrvaptfeevyatelset.mrdrlkkkkynvls.....alelqetdvkldlil 156 lld+G G G+ ++ ap+f++v a + se+ +++ ++ ++ ++ a +l dv d+i+ tr|H2XQ96|H2XQ96_CIOIN 6 FLLDVGCGGGQSVNIFAPYFNQVLAIDPSENqLKEARSQNQFAHVTykqgnAEKLPRDDVSVDVIT 71 59*************************998613444444455544411110333555666666665 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (265 nodes) Target sequences: 16678 (5370518 residues searched) Passed MSV filter: 404 (0.0242235); expected 333.6 (0.02) Passed bias filter: 275 (0.0164888); expected 333.6 (0.02) Passed Vit filter: 37 (0.00221849); expected 16.7 (0.001) Passed Fwd filter: 12 (0.000719511); expected 0.2 (1e-05) Initial search space (Z): 16678 [actual number of targets] Domain search space (domZ): 12 [number of targets reported over threshold] # CPU time: 0.13u 0.01s 00:00:00.14 Elapsed: 00:00:00.04 # Mc/sec: 35579.68 // [ok]