# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/DREV.hmm.txt # target sequence database: proteomes/Danio_rerio.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: DREV [M=265] Accession: PF05219.11 Description: DREV methyltransferase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.5e-107 356.8 0.0 1e-106 356.4 0.0 1.2 1 tr|F1R335|F1R335_DANRE Methyltransferase-like 9 OS=Dani ------ inclusion threshold ------ 0.01 15.4 0.0 0.02 14.5 0.0 1.4 1 tr|F1QE45|F1QE45_DANRE Methyltransferase-like 27 OS=Dan 0.02 14.5 0.1 0.058 13.0 0.0 1.7 2 sp|Q6NWG4|ANM6_DANRE Protein arginine N-methyltransfe 0.033 13.8 0.0 0.039 13.6 0.0 1.1 1 tr|A0A2R8Q1A0|A0A2R8Q1A0_DANRE Uncharacterized protein OS=Danio 0.057 13.0 0.0 0.091 12.4 0.0 1.3 1 tr|B3DIQ7|B3DIQ7_DANRE Methyltransferase-like 22 OS=Dan 0.069 12.8 0.0 0.12 11.9 0.0 1.4 1 tr|Q1LYQ0|Q1LYQ0_DANRE Novel protein OS=Danio rerio OX= 0.075 12.6 0.0 0.11 12.1 0.0 1.3 1 sp|A3KP37|NDUF5_DANRE Arginine-hydroxylase NDUFAF5, mi 0.093 12.3 0.0 0.13 11.8 0.0 1.2 1 tr|F1QJM0|F1QJM0_DANRE Zgc:162780 OS=Danio rerio OX=795 0.098 12.2 0.0 0.15 11.7 0.0 1.2 1 tr|B0S688|B0S688_DANRE rRNA adenine N(6)-methyltransfer 0.12 11.9 0.0 0.61 9.6 0.0 2.0 2 sp|Q6DC04|CARM1_DANRE Histone-arginine methyltransfera Domain annotation for each sequence (and alignments): >> tr|F1R335|F1R335_DANRE Methyltransferase-like 9 OS=Danio rerio OX=7955 GN=mettl9 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 356.4 0.0 4.1e-110 1e-106 1 265 [] 55 316 .. 55 316 .. 0.98 Alignments for each domain: == domain 1 score: 356.4 bits; conditional E-value: 4.1e-110 DREV 1 Wyvlnre.lseslqalfvaslpdaetqsflenskklsanlfiqlyhalassilslfmsktdinGllgrGsmfvlseeqfrkllaiek 86 Wy + + l es+ ++fv+s++d+etq fl++s ++s+++f+qlyh+l ssi+s ++s+t+inG+lgrGsmfv+s +qfr+ll i+ tr|F1R335|F1R335_DANRE 55 WYRCCPDlLGESVSSVFVQSHLDEETQAFLQRSVEKSSWIFTQLYHSLFSSIFSPIISRTSINGFLGRGSMFVFSRDQFRRLLRIG- 140 9988777699****************************************************************************. PP DREV 87 espasdqedkklldlGaGdGeitkrvaptfeevyatelsetmrdrlkkkkynvlsalelqetdvkldlilclnlldrcfdplklled 173 +d++ +++ldlGaGdG +t+ + ++f+evyate+s+ m+++l++k+y +l++ e+q t++++dli+clnlldrc++plkll+d tr|F1R335|F1R335_DANRE 141 ----PDWRAQRMLDLGAGDGGVTEVMGSHFHEVYATEVSTPMKWHLQRKNYSLLGIDEWQCTGLQYDLISCLNLLDRCDEPLKLLQD 223 ....9********************************************************************************** PP DREV 174 irsalep.ngrvivalvlPvshyvetntgksekpsellevkGrsyeeevarli.evlkkagfeveaftrlPylceGdlnnsfyyldd 258 irsal p gr i+a vlP+++yvet + ++ +p++ ++v+G+s+ee+v++l +v+ ++g e++a trlPylceGd+++++y+ldd tr|F1R335|F1R335_DANRE 224 IRSALVPeTGRLILAAVLPFQPYVETGG-SWVRPKQHIQVQGKSWEEQVTHLStQVFPQVGLELQAVTRLPYLCEGDMYRDYYVLDD 309 *******89****************965.***********************99********************************* PP DREV 259 aifvlkk 265 a+f+lk+ tr|F1R335|F1R335_DANRE 310 AVFILKP 316 *****97 PP >> tr|F1QE45|F1QE45_DANRE Methyltransferase-like 27 OS=Danio rerio OX=7955 GN=mettl27 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.5 0.0 7.9e-06 0.02 89 186 .. 68 172 .. 53 175 .. 0.78 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 7.9e-06 DREV 89 pasdqedkklldlGaGdGeitkrvapt.feevyatelsetmrdrlkkkk.ynvlsale.....lqetdvkldlilclnlldrcfdpl 168 ++ d+e+ ++ld+ G G ++k+++ + f + + s +m + kk + y+ l + +d++ + l pl tr|F1QE45|F1QE45_DANRE 68 FNDDREKATVLDVACGTGLVSKHLKRMgFRHFDGVDGSLRMLEGAKKTGlYKQLMHCMlgqdrIPVKAETYDVVIIVGALSVGQVPL 154 68899******************987549999999******99888876466655544110014444557***************** PP DREV 169 klledirsalepngrviv 186 k++++++ a +p g v + tr|F1QE45|F1QE45_DANRE 155 KVIRELWDATKPGGYVCM 172 ************998865 PP >> sp|Q6NWG4|ANM6_DANRE Protein arginine N-methyltransferase 6 OS=Danio rerio OX=7955 GN=prmt6 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.0 2.3e-05 0.058 89 140 .. 50 102 .. 40 140 .. 0.78 2 ? -1.7 0.0 0.67 1.7e+03 239 264 .. 276 301 .. 263 302 .. 0.83 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 2.3e-05 DREV 89 pasdqedkklldlGaGdGeitkrvapt.feevyatelsetmrdrlkkkkynvl 140 + e k +ld+GaG G ++ a+ +vya e+s+ + +k k n + sp|Q6NWG4|ANM6_DANRE 50 NSKSIEGKVVLDVGAGTGVLSLFCAQAgARKVYAVEASSIADQAVKIVKLNQM 102 445578899*************998762678*******988887777776655 PP == domain 2 score: -1.7 bits; conditional E-value: 0.67 DREV 239 trlPylceGdlnnsfyylddaifvlk 264 P+ e ++ + yldda+ v++ sp|Q6NWG4|ANM6_DANRE 276 STSPFKAETHWKQAVLYLDDAVDVMQ 301 5679999999999********98875 PP >> tr|A0A2R8Q1A0|A0A2R8Q1A0_DANRE Uncharacterized protein OS=Danio rerio OX=7955 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.0 1.5e-05 0.039 76 182 .. 25 134 .. 20 158 .. 0.66 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 1.5e-05 DREV 76 eqfrkllaiekespasdqedkklldlGaGdGeitkrvaptfeevyatelsetmrdr......lkkkkynvlsalelqet 148 e k+l+ ++++ s + +d+G G G+ t +ap+f +v t++s + + ++ a el tr|A0A2R8Q1A0|A0A2R8Q1A0_DANRE 25 ELIGKVLQFHRNNEYS--SNGLAVDVGCGSGQGTLLLAPHFTRVVGTDISPAQLEMgrkhvnIPNVSFRESPAEELPFE 101 5555666655443333..455568*************************975433200011122344555555566666 PP DREV 149 dvkldlilclnlldrcfdplklledirsalepng 182 d dl++++ + fd ++l++ +l+p+g tr|A0A2R8Q1A0|A0A2R8Q1A0_DANRE 102 DGSVDLVTAMSAFH-WFDHSRFLQEADRVLKPHG 134 77788888888775.4666677788888888844 PP >> tr|B3DIQ7|B3DIQ7_DANRE Methyltransferase-like 22 OS=Danio rerio OX=7955 GN=mettl22 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 3.5e-05 0.091 89 133 .. 152 196 .. 142 222 .. 0.84 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 3.5e-05 DREV 89 pasdqedkklldlGaGdGeitkrvaptfeevyatelsetmrdrlk 133 +s ++ ++l+lGaG G + +a + vy t++ e + + + tr|B3DIQ7|B3DIQ7_DANRE 152 QSSMFKGATVLELGAGTGLTSIVMAMVAKTVYCTDVGEDLLNMCQ 196 45678899*************9**************998877655 PP >> tr|Q1LYQ0|Q1LYQ0_DANRE Novel protein OS=Danio rerio OX=7955 GN=CH211-31O18.2-001 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 4.8e-05 0.12 92 182 .. 39 134 .. 20 142 .. 0.74 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 4.8e-05 DREV 92 dqedkklldlGaGdGeitkrvaptfeevyatelsetmrdrlk......kkkynvlsalelqetdvkldlilclnlldrcfdplklle 172 ++ ++ +dlG G G+ ++ ++p+f++v ++se + + + y+v +a el d dl+++ fd+ ++++ tr|Q1LYQ0|Q1LYQ0_DANRE 39 GKPHQLAVDLGCGTGQTSRPLTPYFQQVVGIDVSESQVEEARavqgfpNLTYRVGTAEELPFPDASVDLLTAASA-AHWFDAERFVK 124 44444558***********************99987665433111222678999999999999999999998765.45677777788 PP DREV 173 dirsalepng 182 + + +l+p+g tr|Q1LYQ0|Q1LYQ0_DANRE 125 EAQRVLKPHG 134 7777777765 PP >> sp|A3KP37|NDUF5_DANRE Arginine-hydroxylase NDUFAF5, mitochondrial OS=Danio rerio OX=7955 GN=ndufaf5 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 4.1e-05 0.11 98 189 .. 73 169 .. 62 218 .. 0.79 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 4.1e-05 DREV 98 lldlGaGdGeitkrvapt.feevyatelse.tmrdrlkkk..kynvlsale.lqetdvkldlilclnlldrcfdplklledirsalep 180 ld+G G +i++++++ +e+++ t++s+ +r+r v++ e l + +dl+l+ + d l+ i+++l+p sp|A3KP37|NDUF5_DANRE 73 ALDVGCGRSHIAEHLSKEvVERLFLTDISSsSLRNRKTSDipAQCVMADEEfLPFKENTFDLVLSSLSMHWINDLPGALRQIHQVLKP 160 59*************8751678*****9862567765433225678888886666788899998766667777777778999999999 PP DREV 181 ngrvivalv 189 +g i a+v sp|A3KP37|NDUF5_DANRE 161 DGVFIGAMV 169 999998887 PP >> tr|F1QJM0|F1QJM0_DANRE Zgc:162780 OS=Danio rerio OX=7955 GN=zgc:162780 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.0 5.2e-05 0.13 78 182 .. 27 134 .. 20 159 .. 0.65 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 5.2e-05 DREV 78 frkllaiekespasdqedkklldlGaGdGeitkrvaptfeevyatelsetmrdr......lkkkkynvlsalelqetdvkldlilcl 158 k+l+ ++++ s + +d+G G G+ t +ap+f +v t++s + + ++ a el d dl++++ tr|F1QJM0|F1QJM0_DANRE 27 IGKVLQFHRNNEYS--SNGLAVDVGCGSGQGTLLLAPHFTRVVGTDISPAQLEMgrkhvnIPNVSFRESPAEELPFEDGSVDLVTAM 111 55566555433333..455568*************************9654332000111223345555555566667777888888 PP DREV 159 nlldrcfdplklledirsalepng 182 + fd ++l++ +l+p+g tr|F1QJM0|F1QJM0_DANRE 112 SAFH-WFDHSRFLQEADRVLKPHG 134 8775.4566677777777777743 PP >> tr|B0S688|B0S688_DANRE rRNA adenine N(6)-methyltransferase OS=Danio rerio OX=7955 GN=dimt1l PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 5.7e-05 0.15 82 135 .. 36 90 .. 14 108 .. 0.80 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 5.7e-05 DREV 82 laiekes.pasdqedkklldlGaGdGeitkrvaptfeevyatelsetmrdrlkkk 135 l++++ a+ + + +l++G G G++t ++ + ++v a el +++ l+k+ tr|B0S688|B0S688_DANRE 36 LVVNGIIeKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDTRLVAELQKR 90 555554303444456779**********************************996 PP >> sp|Q6DC04|CARM1_DANRE Histone-arginine methyltransferase CARM1 OS=Danio rerio OX=7955 GN=carm1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.4 0.0 0.56 1.4e+03 95 112 .. 8 25 .. 3 29 .. 0.83 2 ? 9.6 0.0 0.00024 0.61 88 127 .. 152 192 .. 139 208 .. 0.82 Alignments for each domain: == domain 1 score: -1.4 bits; conditional E-value: 0.56 DREV 95 dkklldlGaGdGeitkrv 112 ++ll +G +G+i ++ sp|Q6DC04|CARM1_DANRE 8 GVRLLSIGDANGDIQRHS 25 689***********9875 PP == domain 2 score: 9.6 bits; conditional E-value: 0.00024 DREV 88 spasdqedkklldlGaGdGeitkrvapt.feevyatelset 127 + +d++dk +ld+G G G ++ a+ +vya e+s+ sp|Q6DC04|CARM1_DANRE 152 QNHTDFKDKVVLDVGCGSGILSFFAAQAgARKVYAVEASTM 192 567899**************998877652678*****9964 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (265 nodes) Target sequences: 25687 (13798380 residues searched) Passed MSV filter: 645 (0.02511); expected 513.7 (0.02) Passed bias filter: 504 (0.0196208); expected 513.7 (0.02) Passed Vit filter: 47 (0.00182972); expected 25.7 (0.001) Passed Fwd filter: 10 (0.000389302); expected 0.3 (1e-05) Initial search space (Z): 25687 [actual number of targets] Domain search space (domZ): 10 [number of targets reported over threshold] # CPU time: 0.25u 0.01s 00:00:00.26 Elapsed: 00:00:00.10 # Mc/sec: 36565.71 // [ok]