# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/DREV.hmm.txt # target sequence database: proteomes/Dictyostelium_discoideum.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: DREV [M=265] Accession: PF05219.11 Description: DREV methyltransferase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.6e-54 182.8 1.2 7.8e-54 182.1 1.2 1.3 1 tr|Q54U59|Q54U59_DICDI Uncharacterized protein OS=Dictyostel 0.005 15.5 0.0 0.0097 14.5 0.0 1.4 1 sp|Q54QK7|DIM1_DICDI Probable dimethyladenosine transferas 0.0066 15.1 0.0 0.0093 14.6 0.0 1.3 1 tr|Q54UI9|Q54UI9_DICDI Uncharacterized protein OS=Dictyostel 0.0082 14.8 0.0 0.018 13.7 0.0 1.5 1 tr|Q54C42|Q54C42_DICDI Uncharacterized protein OS=Dictyostel ------ inclusion threshold ------ 0.019 13.6 0.0 0.025 13.2 0.0 1.3 1 sp|Q55EX9|Y8948_DICDI Putative methyltransferase DDB_G02689 Domain annotation for each sequence (and alignments): >> tr|Q54U59|Q54U59_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB_G0281259 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 182.1 1.2 3e-57 7.8e-54 11 264 .. 126 390 .. 116 391 .. 0.87 Alignments for each domain: == domain 1 score: 182.1 bits; conditional E-value: 3e-57 DREV 11 slqalfvaslpdaetqsflenskklsanlfiqlyhalassilslfmsktdinGllgrGsmfvlseeqfrkllaiekesp........ 89 l + f++++ d++t f+ ++ + ++ + + a+ i+s +++ktdi G++g+G+m+ ls q++++l+i++ p tr|Q54U59|Q54U59_DICDI 126 YLMNYFIQTEFDKDTMDFIMETPR------WNFVSNAANWIMSWMYTKTDIMGFIGKGNMMCLSTYQYKQILKINRTLPtikfdeed 206 5678999********999988765......567889999***********************************9764411111111 PP DREV 90 asdqedkk.....lldlGaGdGeitkrvaptfeevyatelsetmrdrlkkkkynvlsalelqetd....vkldlilclnlldrcfdp 167 + dq++ k lld+GaG G t ++p f++v ate+s+ m+ l+kk+ + + l+l+ d ++d+++cln+ldrc +p tr|Q54U59|Q54U59_DICDI 207 DNDQDPLKvyyesLLDIGAGCGSTTLSMKPLFKNVTATEASKGMIYSLNKKGIDSVFCLDLETCDqlknKQYDIVSCLNVLDRCEKP 293 34555543223338****************************************99999987665222269**************** PP DREV 168 lklledirsalepngrvivalvlPvshyvetntgksekpsellevkGrsyeeevarli.evlkkagfeveaftrlPylceGdlnnsf 253 + ll+ i++ l+png+ i+a+v+P+++yve+ + + p e ++ + ++ e v+++ +v+ + +fe+++ft Py+ eGd + tr|Q54U59|Q54U59_DICDI 294 ISLLNTIKKFLKPNGKLILAVVFPFNPYVEFGG-IDNSPIETINLDQETLSEYVDSFNkQVFIPNNFEIDSFTVGPYISEGDALYQN 379 ******************************977.88899999***************999***********************999* PP DREV 254 yylddaifvlk 264 y+l+d+ifvlk tr|Q54U59|Q54U59_DICDI 380 YVLTDVIFVLK 390 *********98 PP >> sp|Q54QK7|DIM1_DICDI Probable dimethyladenosine transferase OS=Dictyostelium discoideum OX=44689 GN=dimt1 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.5 0.0 3.8e-06 0.0097 93 135 .. 54 96 .. 34 107 .. 0.85 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 3.8e-06 DREV 93 qedkklldlGaGdGeitkrvaptfeevyatelsetmrdrlkkk 135 + + ++l++G G G++t ++ + ++v a e+ +m l+k+ sp|Q54QK7|DIM1_DICDI 54 KSTDTVLEIGPGTGNLTMKLLENCKKVIAIEVDPRMAAELQKR 96 34789***********************************996 PP >> tr|Q54UI9|Q54UI9_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB_G0281053 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.6 0.0 3.7e-06 0.0093 93 134 .. 47 90 .. 21 154 .. 0.80 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 3.7e-06 DREV 93 qedkklldlGaGdGeitkrvaptf..eevyatelsetmrdrlkk 134 e+ k+ld+GaG G ++ + + +e+ at++s+ m+d l+ tr|Q54UI9|Q54UI9_DICDI 47 NENIKILDVGAGFGVLSIYASTNYpnSEIIATDISKCMIDSLNY 90 35889*********99998887763378************9964 PP >> tr|Q54C42|Q54C42_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0191845 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.7 0.0 7e-06 0.018 76 144 .. 409 478 .. 394 487 .. 0.82 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 7e-06 DREV 76 eqfrkllaiekespasdqedkklldlGaGdGeitkrvaptfeevyatels.etmrdrlkkkkynvlsale 144 + ll + ++a +d++lld+ G G i + +++ +++v e+s ++d ++ k n + + e tr|Q54C42|Q54C42_DICDI 409 TKATELLYSKVLDWAQVSQDTTLLDICCGTGTIGQCISKKVKKVIGLEISpDAVIDSINNAKLNKIDNAE 478 4556788888899***9********************************934577888888877776666 PP >> sp|Q55EX9|Y8948_DICDI Putative methyltransferase DDB_G0268948 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0268948 P # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.0 9.9e-06 0.025 92 156 .. 42 109 .. 29 192 .. 0.71 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 9.9e-06 DREV 92 dqedkklldlGaGdGeitkrvaptfeevyatelsetmrdrlkkk...kynvlsalelqetdvkldlil 156 d + +d+GaG G+ t r+a++f++v e s+ +++ +k +y++ +a +++ dli+ sp|Q55EX9|Y8948_DICDI 42 DEKRDLAIDIGAGSGQATVRLAKYFKKVIGFEPSQGQIENAEKTdnvEYRLSAAEKIDLPSGSVDLIT 109 55666679************************999887766554111566544443444444555555 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (265 nodes) Target sequences: 12739 (6856946 residues searched) Passed MSV filter: 473 (0.0371301); expected 254.8 (0.02) Passed bias filter: 130 (0.0102049); expected 254.8 (0.02) Passed Vit filter: 13 (0.00102049); expected 12.7 (0.001) Passed Fwd filter: 5 (0.000392495); expected 0.1 (1e-05) Initial search space (Z): 12739 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.12u 0.01s 00:00:00.13 Elapsed: 00:00:00.05 # Mc/sec: 36341.81 // [ok]