# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/DREV.hmm.txt # target sequence database: proteomes/Mus_musculus.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: DREV [M=265] Accession: PF05219.11 Description: DREV methyltransferase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.4e-139 462.0 0.1 6.2e-139 461.8 0.1 1.0 1 sp|Q9EPL4|METL9_MOUSE Methyltransferase-like protein 9 OS=Mu ------ inclusion threshold ------ 0.011 15.1 0.0 0.019 14.3 0.0 1.3 1 sp|A2APY7|NDUF5_MOUSE Arginine-hydroxylase NDUFAF5, mitochon 0.021 14.3 0.0 0.034 13.6 0.0 1.2 1 sp|Q3U3W5|ANM9_MOUSE Protein arginine N-methyltransferase 9 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 sp|Q9R144|ANM2_MOUSE Protein arginine N-methyltransferase 2 0.17 11.3 0.0 0.85 9.0 0.0 2.0 2 sp|Q9WVG6|CARM1_MOUSE Histone-arginine methyltransferase CAR Domain annotation for each sequence (and alignments): >> sp|Q9EPL4|METL9_MOUSE Methyltransferase-like protein 9 OS=Mus musculus OX=10090 GN=Mettl9 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 461.8 0.1 1.4e-142 6.2e-139 1 265 [] 56 317 .. 56 317 .. 1.00 Alignments for each domain: == domain 1 score: 461.8 bits; conditional E-value: 1.4e-142 DREV 1 Wyvlnre.lseslqalfvaslpdaetqsflenskklsanlfiqlyhalassilslfmsktdinGllgrGsmfvlseeqfrkllaieke 87 Wyv+nre l+eslq++fv+s++d++tq+fl+ns+++s++lfiqlyh+++ss++slfms+t+inGllgrGsmfv+s++qf++ll i+ sp|Q9EPL4|METL9_MOUSE 56 WYVCNREkLCESLQSVFVQSYLDQGTQIFLNNSIEKSGWLFIQLYHSFVSSVFSLFMSRTSINGLLGRGSMFVFSPDQFQRLLRIN-- 141 *************************************************************************************9.. PP DREV 88 spasdqedkklldlGaGdGeitkrvaptfeevyatelsetmrdrlkkkkynvlsalelqetdvkldlilclnlldrcfdplklledir 175 +d+++++lldlGaGdGe+tk+++p+fee+yatelsetm+++l+kkky+vl+++e+q+t++++d+i+clnlldrc++pl+ll+dir sp|Q9EPL4|METL9_MOUSE 142 ---PDWKTHRLLDLGAGDGEVTKIMSPHFEEIYATELSETMIWQLQKKKYRVLGINEWQNTGFQYDVISCLNLLDRCDQPLTLLKDIR 226 ...9************************************************************************************ PP DREV 176 salep.ngrvivalvlPvshyvetntgksekpsellevkGrsyeeevarlievlkkagfeveaftrlPylceGdlnnsfyylddaifv 262 s+lep +grvi+alvlP+++yve+++gk+ekpse+le+kG+++ee+v++l+ev++kagf+veaftrlPylceGd++n++y+ldda+fv sp|Q9EPL4|METL9_MOUSE 227 SVLEPtQGRVILALVLPFHPYVENVGGKWEKPSEILEIKGQNWEEQVNSLPEVFRKAGFVVEAFTRLPYLCEGDMYNDYYVLDDAVFV 314 *****9********************************************************************************** PP DREV 263 lkk 265 l++ sp|Q9EPL4|METL9_MOUSE 315 LRP 317 986 PP >> sp|A2APY7|NDUF5_MOUSE Arginine-hydroxylase NDUFAF5, mitochondrial OS=Mus musculus OX=10090 GN=Ndufaf5 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.3 0.0 4.4e-06 0.019 99 185 .. 94 185 .. 85 190 .. 0.83 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 4.4e-06 DREV 99 ldlGaGdGeitkrv.aptfeevyatelset.mrdrlkkk..kynvlsale.lqetdvkldlilclnlldrcfdplklledirsalepn 181 ld+G G G i++++ ++t+ +++ t+++e+ +++ l+ n+l+ e l + +dl+++ l d + le i+ +l+p+ sp|A2APY7|NDUF5_MOUSE 94 LDIGCGRGYIAQHLdKETVGKIFQTDIAEHaLKNSLETDipTVNILADEEfLPFQENTFDLVVSSLSLHWVNDLPRALEQIHYVLKPD 181 9************944689*******9875278888764337999**999655567889999888888999999999**********9 PP DREV 182 grvi 185 g + sp|A2APY7|NDUF5_MOUSE 182 GVFV 185 9766 PP >> sp|Q3U3W5|ANM9_MOUSE Protein arginine N-methyltransferase 9 OS=Mus musculus OX=10090 GN=Prmt9 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.6 0.0 7.5e-06 0.034 71 130 .. 154 214 .. 145 232 .. 0.81 Alignments for each domain: == domain 1 score: 13.6 bits; conditional E-value: 7.5e-06 DREV 71 fvlseeqfrkllaiekespasdqedkklldlGaGdGeitkrvapt.feevyatelsetmrd 130 f++ ++ r ++ + a ++++ld+G+G G ++ ++ + vya els+tm + sp|Q3U3W5|ANM9_MOUSE 154 FIMLNDTRRNMVYNAAIQKAVCLGSRTVLDIGTGTGILSMFAKKAgAQSVYACELSKTMYE 214 66666666777777778888888999**********9999877652667**********75 PP >> sp|Q9R144|ANM2_MOUSE Protein arginine N-methyltransferase 2 OS=Mus musculus OX=10090 GN=Prmt2 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.0 0.0 4.5e-05 0.2 90 128 .. 145 185 .. 131 205 .. 0.82 Alignments for each domain: == domain 1 score: 11.0 bits; conditional E-value: 4.5e-05 DREV 90 asdqedkklldlGaGdGeitkrvaptfee..vyatelsetm 128 + +dk +ld+G G G i+ a + vya e+s sp|Q9R144|ANM2_MOUSE 145 KESLKDKVILDVGCGTGIISLFCAHHARPkaVYAVEASDMA 185 445799****************999986556******9754 PP >> sp|Q9WVG6|CARM1_MOUSE Histone-arginine methyltransferase CARM1 OS=Mus musculus OX=10090 GN=Carm1 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.0 0.37 1.6e+03 96 113 .. 36 53 .. 29 60 .. 0.85 2 ? 9.0 0.0 0.00019 0.85 88 127 .. 179 219 .. 171 234 .. 0.81 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 0.37 DREV 96 kklldlGaGdGeitkrva 113 +ll +G +Gei ++ + sp|Q9WVG6|CARM1_MOUSE 36 ARLLTIGDANGEIQRHAE 53 689**********99865 PP == domain 2 score: 9.0 bits; conditional E-value: 0.00019 DREV 88 spasdqedkklldlGaGdGeitkrvapt.feevyatelset 127 + +d++dk +ld+G G G ++ a+ ++ya e+s+ sp|Q9WVG6|CARM1_MOUSE 179 QNHTDFKDKIVLDVGCGSGILSFFAAQAgARKIYAVEASTM 219 567899**************998877652678*****9964 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (265 nodes) Target sequences: 22289 (11757923 residues searched) Passed MSV filter: 423 (0.018978); expected 445.8 (0.02) Passed bias filter: 305 (0.0136839); expected 445.8 (0.02) Passed Vit filter: 34 (0.00152542); expected 22.3 (0.001) Passed Fwd filter: 5 (0.000224326); expected 0.2 (1e-05) Initial search space (Z): 22289 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.21u 0.01s 00:00:00.22 Elapsed: 00:00:00.10 # Mc/sec: 31158.50 // [ok]