# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/DREV.hmm.txt # target sequence database: proteomes/Nematostella_vectensis.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: DREV [M=265] Accession: PF05219.11 Description: DREV methyltransferase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.8e-87 293.2 0.0 2.1e-87 293.0 0.0 1.0 1 tr|A7SGS8|A7SGS8_NEMVE Predicted protein OS=Nematostella vec 0.00018 21.2 0.3 0.0014 18.2 0.2 2.2 2 tr|A7RV37|A7RV37_NEMVE Predicted protein OS=Nematostella vec 0.0038 16.8 0.0 0.0066 16.0 0.0 1.4 1 tr|A7S108|A7S108_NEMVE Predicted protein OS=Nematostella vec 0.0086 15.6 0.0 0.012 15.2 0.0 1.3 1 tr|A7T9Z7|A7T9Z7_NEMVE Predicted protein OS=Nematostella vec 0.0087 15.6 0.0 0.012 15.2 0.0 1.3 1 tr|A7SZN3|A7SZN3_NEMVE Predicted protein OS=Nematostella vec ------ inclusion threshold ------ 0.013 15.1 0.0 0.021 14.4 0.0 1.3 1 tr|A7RW11|A7RW11_NEMVE rRNA adenine N(6)-methyltransferase O 0.03 13.9 0.0 0.055 13.0 0.0 1.3 1 tr|A7RLV9|A7RLV9_NEMVE Predicted protein OS=Nematostella vec 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 tr|A8DWI0|A8DWI0_NEMVE Predicted protein (Fragment) OS=Nemat 0.14 11.6 0.0 0.21 11.1 0.0 1.3 1 tr|A7S2R8|A7S2R8_NEMVE Ubiquinone biosynthesis O-methyltrans Domain annotation for each sequence (and alignments): >> tr|A7SGS8|A7SGS8_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g117903 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 293.0 0.0 7.7e-91 2.1e-87 1 265 [] 17 275 .. 17 275 .. 0.98 Alignments for each domain: == domain 1 score: 293.0 bits; conditional E-value: 7.7e-91 DREV 1 Wyvlnre.lseslqalfvaslpdaetqsflenskklsanlfiqlyhalassilslfmsktdinGllgrGsmfvlseeqfrkllaiek 86 Wy +n + l+ lq++f + +d++ +fl+n +++ +f+q + + + i++lfms t inG+l+rGsm ++s +qfr ll ++ tr|A7SGS8|A7SGS8_NEMVE 17 WYECNVSdLPFELQTKFLQEGLDDGGRKFLQNCYDKTDAFFTQFGQMVFKGIFNLFMSVTTINGILNRGSMHIFSAQQFRSLLGVD- 102 *****998*****************************************************************************9. PP DREV 87 espasdqedkklldlGaGdGeitkrvaptfeevyatelsetmrdrlkkkkynvlsalelqetdvkldlilclnlldrcfdplklled 173 +++ +klldlGaGdG++t+ +ap+f+evy te s mr+rl +k+y vl + ++ ++ +d+i clnlldrc +p +ll tr|A7SGS8|A7SGS8_NEMVE 103 ----DKWKANKLLDLGAGDGKVTEVMAPHFKEVYVTEQSVSMRWRLGWKGYTVLDIDDWSSAKESYDVIGCLNLLDRCAKPRTLLAG 185 ....66889****************************************************************************** PP DREV 174 irsalep.ngrvivalvlPvshyvetntgksekpsellevkGrsyeeevarli.evlkkagfeveaftrlPylceGdlnnsfyyldd 258 ++ al+p grvi+a+vlP+++ v+++ p el+ v G+++ee+v +l+ +v+ +ag+eve+ftrlPylceGdl++sfy l d tr|A7SGS8|A7SGS8_NEMVE 186 MKHALKPeTGRVIIAVVLPFNPCVDNVI----SPTELITVVGETWEEQVISLVeDVFTPAGYEVERFTRLPYLCEGDLYDSFYSLSD 268 *******99****************998....89*******************89******************************** PP DREV 259 aifvlkk 265 +fvlk+ tr|A7SGS8|A7SGS8_NEMVE 269 TVFVLKP 275 *****97 PP >> tr|A7RV37|A7RV37_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g234527 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.8 0.0 0.1 2.8e+02 109 137 .. 46 74 .. 40 109 .. 0.65 2 ! 18.2 0.2 5.1e-07 0.0014 66 176 .. 111 229 .. 79 289 .. 0.74 Alignments for each domain: == domain 1 score: 0.8 bits; conditional E-value: 0.1 DREV 109 tkrvaptfeevyatelsetmrdrlkkkky 137 +k +++ + +v+ate s + ++k tr|A7RV37|A7RV37_NEMVE 46 SKAIKESLAKVFATEKSRALPPIIRKGPL 74 6788899999******9988666666555 PP == domain 2 score: 18.2 bits; conditional E-value: 5.1e-07 DREV 66 grGsmfvlsee......qfrkllaiekespasdqedkklldlGaGdGeitkrv.aptfeevyatelsetmrdrlkkkkynvlsalel 145 ++G+m+vl ++ + ai ++ + +++dk++l lG GdG i ++v ++ ++v +e+ +m l k+ + + + tr|A7RV37|A7RV37_NEMVE 111 QFGNMLVLNNDinlaesDLSYTKAITGN-GKENYKDKTVLILGGGDGGILHHVlKEEPKQVIMAEID-QMVVDLAVKHLRGICGDSM 195 5677777655421111122223333333.345699**************999724566779999986.6888999999999987765 PP DREV 146 qe.tdvkldlil..clnlldrcfdplklledirs 176 + + ++++i c++++++c + +kl++ + + tr|A7RV37|A7RV37_NEMVE 196 DSlIGPNYEVIIgdCVEIMNKCINKGKLFDYVIN 229 432699****9656*************9876554 PP >> tr|A7S108|A7S108_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g242091 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 0.0 2.4e-06 0.0066 87 193 .. 41 155 .. 30 192 .. 0.80 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 2.4e-06 DREV 87 espasdqedkklldlGaGdGeitkrvaptfee.....vyatelsetmrdrlkkk..kynvl..salelqetdvkldlilclnlldrc 164 e+ ++ ++ k+l+lGaG G+ t+ v + +e+ v a e +m +++k + +v+ +a ++ d +d +l+ + tr|A7S108|A7S108_NEMVE 41 EDGTPCNREFKILELGAGTGKFTRVVMEVLEKnpnfqVIASEPLPEMCHKFKEVlpGVEVMqfAAEDIPFPDATFDSVLASSSIH-W 126 4455667889*********************99999999*999999988888752345554114566777889999999988775.7 PP DREV 165 fdplklledirsalepngrvivalvlPvs 193 f+ k +++i+ +l++ g va ++P tr|A7S108|A7S108_NEMVE 127 FSNHKSMQEIHRVLKSAGTLGVAYIFPAV 155 8999******************9999965 PP >> tr|A7T9Z7|A7T9Z7_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g248861 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 0.0 4.3e-06 0.012 87 186 .. 28 136 .. 16 180 .. 0.76 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 4.3e-06 DREV 87 espasdqedkklldlGaGdGeitkrvaptfee..........vyatelsetmrdrlkkkkynvlsalelqet.dvkldlilclnlld 162 + + + k +ldlG G G++t +a f++ y el++ ++ + ++ sa + + + +dl+ + +l tr|A7T9Z7|A7T9Z7_NEMVE 28 FPSLPFATAKFVLDLGCGTGDVTGAMAANFSNdasiigidpdKYRVELAKS--NHCSNVQFLQGSAESFPHLgEEYYDLVFSNFVLH 112 55555567889*******************998887776666666666553..4444444544444445544144579999988999 PP DREV 163 rcfdplklledirsalepngrviv 186 + k ++di+ l+p g ++ tr|A7T9Z7|A7T9Z7_NEMVE 113 WIPQRTKAFRDIYDSLKPGGMLVM 136 999999999999999998887665 PP >> tr|A7SZN3|A7SZN3_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g248239 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.2 0.0 4.3e-06 0.012 87 186 .. 28 136 .. 16 183 .. 0.77 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 4.3e-06 DREV 87 espasdqedkklldlGaGdGeitkrvaptfee..........vyatelsetmrdrlkkkkynvlsalelqet.dvkldlilclnlld 162 + + + k +ldlG G G++t +a f++ y el++ ++ + ++ sa + + + +dl+ + +l tr|A7SZN3|A7SZN3_NEMVE 28 FPSLPFATAKFVLDLGCGTGDVTGAMAANFSNdasiigidpdKYRVELAKS--NHCSNVQFLQGSAESFPHLgEEYYDLVFSNFVLH 112 55555567889*******************998887776666666666553..4444444544444445544144579999988999 PP DREV 163 rcfdplklledirsalepngrviv 186 + k ++di+ l+p g ++ tr|A7SZN3|A7SZN3_NEMVE 113 WIPQRTKAFRDIYDSLKPGGMLVM 136 999999999999999998887665 PP >> tr|A7RW11|A7RW11_NEMVE rRNA adenine N(6)-methyltransferase OS=Nematostella vectensis OX=45351 GN=v1g241083 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.4 0.0 7.6e-06 0.021 93 135 .. 50 92 .. 31 108 .. 0.88 Alignments for each domain: == domain 1 score: 14.4 bits; conditional E-value: 7.6e-06 DREV 93 qedkklldlGaGdGeitkrvaptfeevyatelsetmrdrlkkk 135 + + ++l++G G G++t ++ ++ ++v a el +m l+k+ tr|A7RW11|A7RW11_NEMVE 50 RSTDTVLEIGPGTGNLTVKLLEQSKKVIACELDPRMVAELQKR 92 56889***********************************996 PP >> tr|A7RLV9|A7RLV9_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g199029 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.0 2e-05 0.055 77 131 .. 522 575 .. 506 612 .. 0.78 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 2e-05 DREV 77 qfrkllaiekespasdqedkklldlGaGdGeitkrvaptfeevyatelsetmrdr 131 +k++ i ++ +q++++lld+ G G i +a+++++v e+ + + tr|A7RLV9|A7RLV9_NEMVE 522 AAEKMIHII-SRWMGEQKETTLLDICCGTGSIGLCLAKYVSKVIGVEVIQSAVED 575 456777776.78999****************************999986655443 PP >> tr|A8DWI0|A8DWI0_NEMVE Predicted protein (Fragment) OS=Nematostella vectensis OX=45351 GN=v1g226006 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.0 7.9e-05 0.21 95 174 .. 15 99 .. 5 107 .. 0.75 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 7.9e-05 DREV 95 dkklldlGaGdGeitkrvaptfee.vyatelsetmrdrlkkkkynvlsal.e..lqe.tdvkldlilclnlldrcfdplklledi 174 ++ldlG G+Ge+ +a++ + y e+ + + k+ nv+ ++ + l + + +d+++ l + p k+l ++ tr|A8DWI0|A8DWI0_NEMVE 15 GSRVLDLGCGNGELLAWLAEHKQVfGYGLEIDADNIAQCVSKGVNVIEQNlDkgLGNfASNSFDVVVMTQSLQALHYPDKVLAEM 99 579***************9997653488999999999*********987523344441344688888777777777777777665 PP >> tr|A7S2R8|A7S2R8_NEMVE Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Nematostella vectensis OX=45351 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.0 7.8e-05 0.21 94 188 .. 114 219 .. 80 274 .. 0.77 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 7.8e-05 DREV 94 edkklldlGaGdGeitkrvaptfeevyatelse.....tmrdr.lk.....kkkynvlsalelqetdvkldlilclnlldrcfdplk 169 + k+ld+G G G +++ +a +v ++s mr+ l+ k++y+ +++ +l++ + +d +++ ++++ + tr|A7S2R8|A7S2R8_NEMVE 114 DGFKMLDVGCGGGLLAEPLARLGAKVTGIDASArnthvAMRHAsLDpslagKLQYRCITVEQLAQEKKVFDCVVSSEVIEHVTEKES 200 456999*******9999998887776555555311111566532222222489*********9999999****************** PP DREV 170 lledirsalepngrvival 188 ++ i + l+p+g i++ tr|A7S2R8|A7S2R8_NEMVE 201 FIGAISQLLKPRGSLILTT 219 **************99875 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (265 nodes) Target sequences: 24428 (8257945 residues searched) Passed MSV filter: 468 (0.0191583); expected 488.6 (0.02) Passed bias filter: 350 (0.0143278); expected 488.6 (0.02) Passed Vit filter: 39 (0.00159653); expected 24.4 (0.001) Passed Fwd filter: 9 (0.00036843); expected 0.2 (1e-05) Initial search space (Z): 24428 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.17u 0.01s 00:00:00.18 Elapsed: 00:00:00.06 # Mc/sec: 36472.59 // [ok]