# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/DREV.hmm.txt # target sequence database: proteomes/Pan_troglodytes.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: DREV [M=265] Accession: PF05219.11 Description: DREV methyltransferase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.9e-140 464.6 0.1 1e-139 464.4 0.1 1.0 1 tr|H2R0J0|H2R0J0_PANTR METTL9 isoform 1 OS=Pan troglodytes O 0.0053 16.2 0.1 0.012 15.1 0.0 1.6 2 tr|H2QQ96|H2QQ96_PANTR Protein arginine methyltransferase 9 ------ inclusion threshold ------ 0.12 11.8 0.0 0.17 11.3 0.0 1.2 1 tr|H2Q658|H2Q658_PANTR METTL7B isoform 1 OS=Pan troglodytes 0.17 11.3 0.0 0.8 9.1 0.0 2.0 2 tr|H2R0U4|H2R0U4_PANTR CARM1 isoform 1 OS=Pan troglodytes OX 0.2 11.1 0.0 0.31 10.5 0.0 1.2 1 tr|H2PZI7|H2PZI7_PANTR PRMT6 isoform 1 OS=Pan troglodytes OX Domain annotation for each sequence (and alignments): >> tr|H2R0J0|H2R0J0_PANTR METTL9 isoform 1 OS=Pan troglodytes OX=9598 GN=METTL9 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 464.4 0.1 2.2e-143 1e-139 1 265 [] 56 317 .. 56 317 .. 1.00 Alignments for each domain: == domain 1 score: 464.4 bits; conditional E-value: 2.2e-143 DREV 1 Wyvlnre.lseslqalfvaslpdaetqsflenskklsanlfiqlyhalassilslfmsktdinGllgrGsmfvlseeqfrkllaiek 86 Wyv+nre l+eslqa+fv+s++d++tq+fl+ns+++s++lfiqlyh+++ss++slfms+t+inGllgrGsmfv+s++qf++ll+i+ tr|H2R0J0|H2R0J0_PANTR 56 WYVCNREkLCESLQAVFVQSYLDQGTQIFLNNSIEKSGWLFIQLYHSFVSSVFSLFMSRTSINGLLGRGSMFVFSPDQFQRLLKIN- 141 *************************************************************************************9. PP DREV 87 espasdqedkklldlGaGdGeitkrvaptfeevyatelsetmrdrlkkkkynvlsalelqetdvkldlilclnlldrcfdplklled 173 +d+++++lldlGaGdGe+tk+++p+fee+yatelsetm+++l+kkky+vl+++e+q+t++++d+i+clnlldrc++pl+ll+d tr|H2R0J0|H2R0J0_PANTR 142 ----PDWKTHRLLDLGAGDGEVTKIMSPHFEEIYATELSETMIWQLQKKKYRVLGINEWQNTGFQYDVISCLNLLDRCDQPLTLLKD 224 ....9********************************************************************************** PP DREV 174 irsalep.ngrvivalvlPvshyvetntgksekpsellevkGrsyeeevarlievlkkagfeveaftrlPylceGdlnnsfyyldda 259 irs+lep +grvi+alvlP+++yve+++gk+ekpse+le+kG+++ee+v++l+ev++kagf++eaftrlPylceGd++n++y+ldda tr|H2R0J0|H2R0J0_PANTR 225 IRSVLEPtRGRVILALVLPFHPYVENVGGKWEKPSEILEIKGQNWEEQVNSLPEVFRKAGFVIEAFTRLPYLCEGDMYNDYYVLDDA 311 *******9******************************************************************************* PP DREV 260 ifvlkk 265 +fvlk+ tr|H2R0J0|H2R0J0_PANTR 312 VFVLKP 317 ****97 PP >> tr|H2QQ96|H2QQ96_PANTR Protein arginine methyltransferase 9 OS=Pan troglodytes OX=9598 GN=PRMT9 PE=3 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.1 0.0 2.6e-06 0.012 83 129 .. 155 202 .. 134 217 .. 0.78 2 ? -3.9 0.0 1.6 7.5e+03 224 259 .. 443 479 .. 440 481 .. 0.78 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 2.6e-06 DREV 83 aiekespasdqedkklldlGaGdGeitkrvaptfee.vyatelsetmr 129 + a +k +ld+GaG G ++ ++ + vya els+tm tr|H2QQ96|H2QQ96_PANTR 155 YNAAIQKAVCLGSKSVLDIGAGTGILSMFAKKAGAHsVYACELSKTMY 202 444566777778899***********99988776656**********7 PP == domain 2 score: -3.9 bits; conditional E-value: 1.6 DREV 224 liev.lkkagfeveaftrlPylceGdlnnsfyyldda 259 ++ev +++ ++++ l ce d+ +sf +d+ tr|H2QQ96|H2QQ96_PANTR 443 MMEVsCQDCYLRIQSISVLGLECEMDVAKSFTQNKDL 479 6676347788899999999999999999999777665 PP >> tr|H2Q658|H2Q658_PANTR METTL7B isoform 1 OS=Pan troglodytes OX=9598 GN=METTL7B PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 3.8e-05 0.17 125 182 .. 110 168 .. 53 177 .. 0.75 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 3.8e-05 DREV 125 setmrdrlkkkkynvlsale.lqetdvkldlilclnlldrcfdplklledirsalepng 182 s +l+ ++ v + q +d +d+++c +l +p k+l+++r +l+p g tr|H2Q658|H2Q658_PANTR 110 SMAENRHLQYERFVVAPGEDmRQLADGSMDVVVCTLVLCSVQSPRKVLQEVRRVLRPGG 168 333356799999999998885677899*****************************976 PP >> tr|H2R0U4|H2R0U4_PANTR CARM1 isoform 1 OS=Pan troglodytes OX=9598 GN=CARM1 PE=3 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -1.8 0.0 0.36 1.7e+03 96 113 .. 35 52 .. 28 60 .. 0.85 2 ? 9.1 0.0 0.00017 0.8 88 127 .. 178 218 .. 161 234 .. 0.82 Alignments for each domain: == domain 1 score: -1.8 bits; conditional E-value: 0.36 DREV 96 kklldlGaGdGeitkrva 113 +ll +G +Gei ++ + tr|H2R0U4|H2R0U4_PANTR 35 ARLLTIGDANGEIQRHAE 52 689**********99865 PP == domain 2 score: 9.1 bits; conditional E-value: 0.00017 DREV 88 spasdqedkklldlGaGdGeitkrvapt.feevyatelset 127 + +d++dk +ld+G G G ++ a+ ++ya e+s+ tr|H2R0U4|H2R0U4_PANTR 178 QNHTDFKDKIVLDVGCGSGILSFFAAQAgARKIYAVEASTM 218 567899**************998877652678*****9964 PP >> tr|H2PZI7|H2PZI7_PANTR PRMT6 isoform 1 OS=Pan troglodytes OX=9598 GN=PRMT6 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 0.0 6.7e-05 0.31 89 138 .. 78 127 .. 71 132 .. 0.77 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 6.7e-05 DREV 89 pasdqedkklldlGaGdGeitkrvapt.feevyatelsetmrdrlkkkkyn 138 +a+ + k++ld+GaG G ++ a+ +vya e+s ++ + ++n tr|H2PZI7|H2PZI7_PANTR 78 WAA-LRGKTVLDVGAGTGILSIFCAQAgARRVYAVEASAIWQQAREVVRFN 127 555.6789************99888762567*******8776665555555 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (265 nodes) Target sequences: 23008 (11942255 residues searched) Passed MSV filter: 448 (0.0194715); expected 460.2 (0.02) Passed bias filter: 343 (0.0149079); expected 460.2 (0.02) Passed Vit filter: 34 (0.00147775); expected 23.0 (0.001) Passed Fwd filter: 5 (0.000217316); expected 0.2 (1e-05) Initial search space (Z): 23008 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.21u 0.01s 00:00:00.22 Elapsed: 00:00:00.08 # Mc/sec: 39558.72 // [ok]