# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/DREV.hmm.txt
# target sequence database: proteomes/Trypanosoma_brucei.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: DREV [M=265]
Accession: PF05219.11
Description: DREV methyltransferase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
2.1e-56 189.9 0.0 2.6e-56 189.6 0.0 1.0 1 tr|Q584Q2|Q584Q2_TRYB2 DREV methyltransferase, putative OS=T
0.0026 15.9 0.0 0.52 8.3 0.0 2.3 2 tr|Q38FT0|Q38FT0_TRYB2 Uncharacterized protein OS=Trypanosom
0.0099 14.0 0.0 5.2 5.0 0.0 3.2 3 tr|Q582P2|Q582P2_TRYB2 Uncharacterized protein OS=Trypanosom
------ inclusion threshold ------
0.019 13.0 0.0 0.032 12.3 0.0 1.3 1 tr|Q585P9|Q585P9_TRYB2 rRNA adenine N(6)-methyltransferase O
0.021 12.9 0.0 0.05 11.6 0.0 1.5 1 tr|Q38DV8|Q38DV8_TRYB2 Ubiquinone biosynthesis O-methyltrans
Domain annotation for each sequence (and alignments):
>> tr|Q584Q2|Q584Q2_TRYB2 DREV methyltransferase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 189.6 0.0 1.5e-59 2.6e-56 2 264 .. 24 298 .. 23 299 .. 0.88
Alignments for each domain:
== domain 1 score: 189.6 bits; conditional E-value: 1.5e-59
DREV 2 yvlnre.lseslqalfvaslpdaetqsflenskklsanlfiqlyhalassilslfmsktdinGllgrGsmfvlseeqfrkllaie.. 85
y +n + l++++ +++ ++ d+et +l+++ ++sa + l +l f+s t nG++grG mfv+s eq + ll
tr|Q584Q2|Q584Q2_TRYB2 24 YRANIDvLPQHIVTKYFILEKDKETTDWLKEAANVSA------LRILIANLLRHFVSLTTANGIVGRGGMFVVSTEQAANLLLGRti 104
66777779999999***************99999887......58899999*****************************9964411 PP
DREV 86 kespasdqed.....kklldlGaGdGeitkrvaptfeevyatelsetmrdrlkkkkynvlsale.lqetd...vkldlilclnlldr 163
++++ +++ ++lld+GaGdG +t r++p f++v ate s mr+rl +++y+vl + + + d +d+i+cln+ldr
tr|Q584Q2|Q584Q2_TRYB2 105 AQQWTRYRDTmeppfETLLDVGAGDGGVTSRLQPLFKRVTATEFSIPMRWRLWRRGYEVLPYQDpFTNKDgsrRYYDVISCLNVLDR 191
35676544432234469***********************************************988876332469*********** PP
DREV 164 cfdplklledirsalepngrvivalvlPvshyvetntgksekpsellevkG......rsyeeevarli.evlkkagfeveaftrlPy 243
+ pl ll +r l p+g ++a+vlP+ ++ve + + +ps+++ ++G +++e+ + l+ +vl + gf++e++ +lPy
tr|Q584Q2|Q584Q2_TRYB2 192 ADRPLDLLASMRDSLGPEGILLLAVVLPWCPFVEDGS-IKRRPSQMMPMDGgecckgATFEQSLQCLMdNVLVPFGFQLERWCKLPY 277
**********************************988.77888888887665666559**********9****************** PP
DREV 244 lceGdlnnsfyylddaifvlk 264
lceG++ ++ +l+da++vl
tr|Q584Q2|Q584Q2_TRYB2 278 LCEGNMIAEYAVLHDAVMVLT 298
*******************96 PP
>> tr|Q38FT0|Q38FT0_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 8.3 0.0 0.0003 0.52 85 129 .. 126 170 .. 119 183 .. 0.86
2 ! 4.9 0.0 0.0032 5.5 149 191 .. 260 302 .. 251 337 .. 0.81
Alignments for each domain:
== domain 1 score: 8.3 bits; conditional E-value: 0.0003
DREV 85 ekespasdqedkklldlGaGdGeitkrvaptfeevyatelsetmr 129
+++ pa d ++++ ldlG G + ++++f++v + s +
tr|Q38FT0|Q38FT0_TRYB2 126 HEFVPANDGKERRALDLGCAVGASSLEMSKYFSRVVGIDYSVAFI 170
56789999**************************99888887655 PP
== domain 2 score: 4.9 bits; conditional E-value: 0.0032
DREV 149 dvkldlilclnlldrcfdplklledirsalepngrvivalvlP 191
+ ++d +l+ nll r +p kll+ + + l + g +++
tr|Q38FT0|Q38FT0_TRYB2 260 GERFDAVLVANLLCRVPNPRKLLDMLPLLLVSGGILVISSPYS 302
5689********************9999999988888775555 PP
>> tr|Q582P2|Q582P2_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 0.4 0.0 0.08 1.4e+02 108 144 .. 102 138 .. 98 145 .. 0.84
2 ! 3.8 0.0 0.0074 13 83 127 .. 534 578 .. 524 584 .. 0.86
3 ! 5.0 0.0 0.003 5.2 151 170 .. 639 658 .. 627 676 .. 0.83
Alignments for each domain:
== domain 1 score: 0.4 bits; conditional E-value: 0.08
DREV 108 itkrvaptfeevyatelsetmrdrlkkkkynvlsale 144
++ r++p++ee +a + e d l+ +yn ++ e
tr|Q582P2|Q582P2_TRYB2 102 LSMRIRPHLEEAFAVGVDEMSWDDLNEEHYNWPTVEE 138
6889***********9999999999999999766555 PP
== domain 2 score: 3.8 bits; conditional E-value: 0.0074
DREV 83 aiekespasdqedkklldlGaGdGeitkrvaptfeevyatelset 127
++++++ + +k+ ld+ G G i+ ++++f++v + s +
tr|Q582P2|Q582P2_TRYB2 534 VMNQFRCCARTGPKRALDFACGAGRIAFELTSMFDQVVGSDFSAR 578
5677888888899************************99988876 PP
== domain 3 score: 5.0 bits; conditional E-value: 0.003
DREV 151 kldlilclnlldrcfdplkl 170
++ lilc n ldr ++p +
tr|Q582P2|Q582P2_TRYB2 639 DFSLILCWNTLDRSYNPTAV 658
699*************9865 PP
>> tr|Q585P9|Q585P9_TRYB2 rRNA adenine N(6)-methyltransferase OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.3 0.0 1.9e-05 0.032 89 135 .. 83 129 .. 57 140 .. 0.84
Alignments for each domain:
== domain 1 score: 12.3 bits; conditional E-value: 1.9e-05
DREV 89 pasdqedkklldlGaGdGeitkrvaptfeevyatelsetmrdrlkkk 135
a+ + + +l++G G G++t+++ + ++v a e+ +m l+k+
tr|Q585P9|Q585P9_TRYB2 83 KAAVKPTDIVLEIGPGTGNLTEKLLQAAKKVIAFEVDPRMVAELNKR 129
3444556789**********************************986 PP
>> tr|Q38DV8|Q38DV8_TRYB2 Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Trypanosoma brucei brucei (stra
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.6 0.0 2.9e-05 0.05 97 187 .. 69 174 .. 58 180 .. 0.77
Alignments for each domain:
== domain 1 score: 11.6 bits; conditional E-value: 2.9e-05
DREV 97 klldlGaGdGeitkrvaptfee...........vyatelsetmrdrl...kkkkynvlsale.lqetdvkldlilclnlldrcfdpl 168
+ld+G G G +++ +a + a e +++ + + y+ + e ++ + +++l+++ ++++ d+
tr|Q38DV8|Q38DV8_TRYB2 69 SVLDVGCGGGILSESIARLGGDvlgidmckesiAVAEERRQRVLRDItpqASLAYRCVPLHEvVEGEGRQFELVVASEVIEHVSDAA 155
688999999999998888877766666666664445555554443331214578999999995566789****************** PP
DREV 169 klledirsalepngrviva 187
+l+di a +p g +++
tr|Q38DV8|Q38DV8_TRYB2 156 AFLHDICAATKPGGVLVIS 174
************9988887 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (265 nodes)
Target sequences: 8561 (4332363 residues searched)
Passed MSV filter: 129 (0.0150683); expected 171.2 (0.02)
Passed bias filter: 106 (0.0123817); expected 171.2 (0.02)
Passed Vit filter: 11 (0.0012849); expected 8.6 (0.001)
Passed Fwd filter: 5 (0.000584044); expected 0.1 (1e-05)
Initial search space (Z): 8561 [actual number of targets]
Domain search space (domZ): 5 [number of targets reported over threshold]
# CPU time: 0.07u 0.00s 00:00:00.07 Elapsed: 00:00:00.04
# Mc/sec: 28701.90
//
[ok]