# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/EMG1.hmm.txt
# target sequence database:        proteomes/Trypanosoma_brucei.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       EMG1  [M=194]
Accession:   PF03587.13
Description: EMG1/NEP1 methyltransferase
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
      2e-59  199.5   0.0    2.6e-59  199.1   0.0    1.1  1  tr|Q57UH6|Q57UH6_TRYB2  Uncharacterized protein OS=Trypanosom
    2.7e-37  127.3   0.0    3.3e-37  127.0   0.0    1.1  1  tr|Q586T6|Q586T6_TRYB2  Uncharacterized protein OS=Trypanosom


Domain annotation for each sequence (and alignments):
>> tr|Q57UH6|Q57UH6_TRYB2  Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  199.1   0.0   6.2e-63   2.6e-59       1     194 []      25     267 ..      25     267 .. 0.87

  Alignments for each domain:
  == domain 1  score: 199.1 bits;  conditional E-value: 6.2e-63
                             EEEEEES--B--GGSCGGSB--HHHHCGG.TTSTTGGGSS-CHHHHHHHHHHHCSCHHCTT-EEEEEEETTSEEEEE-TT----SSH CS
                    EMG1   1 ivLeeasLelvkvkkkseqLLnsddhkkilkklkreakeaRpDIvHqcLlalldspLnkagllqvyihttknvlIevnpqtRiPrtf 87 
                             i+Le+++L++v+ k + ++LL +++h+   +++k++++e+RpD+vHq+Ll+l+dspLn+ag+lqv+++t+k+v+I+v+p++R+Pr++
  tr|Q57UH6|Q57UH6_TRYB2  25 IILEHCPLAVVRGK-YGFELL-AERHRAHHARYKQDPAEWRPDVVHQALLHLMDSPLNRAGMLQVFLRTKKGVVIAVDPRLRVPRHM 109
                             8************7.******.7889899999******************************************************* PP

                             HHHHHHHHHHHCCSEEEETTEE.SCEEEECS-HHHHCCC-SEEEEE-TTSEE-.................................. CS
                    EMG1  88 krFagLmvqLLkklsirategeekLlkviknpitdhlppgskiillsesaekk.................................. 140
                             + F+++mv++L ++++ra++g+ +Ll+v+knp+tdh+p+++++i ++++++ +                                  
  tr|Q57UH6|Q57UH6_TRYB2 110 RLFEKMMVSCLYRMKVRAANGSVSLLRVVKNPVTDHIPANCTLIRVEKDGDAVpdifaycatcgtnrhadgstsenvgtatacsssa 196
                             ***************************************************778888888888887777777777777777777777 PP

                             ..........................EEEE-SSSS....---HH....EEESSSS---HHHHHHHHHHHCH CS
                    EMG1 141 .........lvdleefv....vkpvvfvigamskgsvkidykee....eisisnypLsaavvcskiltafE 194
                                      +++ ++++     +p++f+ig+mskg+v++ y  +    +i++ ++ +saa++cs i++ fE
  tr|Q57UH6|Q57UH6_TRYB2 197 gsdakephfAQKHRDLAdakqFRPFAFIIGGMSKGDVDAPYAPRaqvkSIRLGDRGMSAAAACSVIIHGFE 267
                             76665555522333333554555888*********9998777645555********************998 PP

>> tr|Q586T6|Q586T6_TRYB2  Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  127.0   0.0   7.7e-41   3.3e-37       1     193 [.      63     270 ..      63     271 .. 0.87

  Alignments for each domain:
  == domain 1  score: 127.0 bits;  conditional E-value: 7.7e-41
                             EEEEEES--B--GGSCGGSB--HHHHCGG.TTSTTGGGSS-CHHHHHHHHHHHCSCHHC.TT-EEEEEE..ETTSEEEEE-TT---- CS
                    EMG1   1 ivLeeasLelvkvkkkseqLLnsddhkkilkklkreakeaRpDIvHqcLlalldspLnk.agllqvyih..ttknvlIevnpqtRiP 84 
                             ++Le+a L l +++     ++++ d +      + + +++RpDIvHqcLlal+ds L + + +l+v+i+   + ++ +ev+p++R P
  tr|Q586T6|Q586T6_TRYB2  63 VILEKAGLLLGREG-----VVDAYDRAGSTTIANASLRDVRPDIVHQCLLALFDSGLAQeQRQLRVFINlfSRGGRTVEVSPSLRPP 144
                             67888888877777.....8888888888999999**********************873679*****977899************* PP

                             SSHHHHHHHHHHHHCCSEEEETTEE.SCEEEECS-HHHHCCC-SEEEEE-TTSEE-..............................E CS
                    EMG1  85 rtfkrFagLmvqLLkklsirategeekLlkviknpitdhlppgskiillsesaekklvdleefv....vkpvv.............f 154
                             rt +rF+gL++ LL+++ +r+++ge +Ll+v+  +++ +lp g+++i+l++  +  + ++++++    ++pv              f
  tr|Q586T6|Q586T6_TRYB2 145 RTLRRFKGLVAALLRDGVVRSQDGE-VLLQVLPGSLAPVLPYGAEVIGLTNAHSAPVRTPTQLAraalENPVDdklqgglkgvagfF 230
                             ************************9.***********************99877444445555555565555577778888888889 PP

                             EEE-SSSS.....---HHEEESSSS---HHHHHHHHHHHC CS
                    EMG1 155 vigamskgsvki.dykeeeisisnypLsaavvcskiltaf 193
                             +i +   gs +  dy+++++++s yp++a+v+cs++++ f
  tr|Q586T6|Q586T6_TRYB2 231 CICCSEDGSLDGvDYVTQQVCLSAYPMTAHVMCSRLCEGF 270
                             9999999976656************************987 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (194 nodes)
Target sequences:                         8561  (4332363 residues searched)
Passed MSV filter:                       207  (0.0241794); expected 171.2 (0.02)
Passed bias filter:                      173  (0.0202079); expected 171.2 (0.02)
Passed Vit filter:                        10  (0.00116809); expected 8.6 (0.001)
Passed Fwd filter:                         2  (0.000233618); expected 0.1 (1e-05)
Initial search space (Z):               8561  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.07u 0.01s 00:00:00.08 Elapsed: 00:00:00.05
# Mc/sec: 16809.57
//
[ok]