# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/Fibrillarin.hmm.txt
# target sequence database:        proteomes/Amphimedon_queenslandica.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       Fibrillarin  [M=226]
Accession:   PF01269.17
Description: Fibrillarin
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence                       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------                       -----------
   5.2e-107  357.4   0.0   6.2e-107  357.1   0.0    1.0  1  tr|A0A1X7UZ07|A0A1X7UZ07_AMPQE  Uncharacterized protein OS=Amphi
    2.6e-06   28.0   0.2      1e-05   26.0   0.0    1.8  2  tr|A0A1X7V969|A0A1X7V969_AMPQE  Uncharacterized protein OS=Amphi
     0.0031   17.9   0.0     0.0048   17.3   0.0    1.3  1  tr|A0A1X7VEF1|A0A1X7VEF1_AMPQE  Uncharacterized protein OS=Amphi
  ------ inclusion threshold ------
      0.059   13.7   0.0      0.092   13.1   0.0    1.4  1  tr|A0A1X7V2C8|A0A1X7V2C8_AMPQE  Uncharacterized protein OS=Amphi
       0.32   11.3   0.0        0.9    9.9   0.0    1.6  2  tr|A0A1X7VHW4|A0A1X7VHW4_AMPQE  Uncharacterized protein OS=Amphi
       0.43   10.9   0.1        3.9    7.8   0.1    2.2  2  tr|A0A1X7UXG8|A0A1X7UXG8_AMPQE  Uncharacterized protein OS=Amphi


Domain annotation for each sequence (and alignments):
>> tr|A0A1X7UZ07|A0A1X7UZ07_AMPQE  Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  357.1   0.0  8.6e-111  6.2e-107       1     225 [.       9     239 ..       9     240 .. 0.98

  Alignments for each domain:
  == domain 1  score: 357.1 bits;  conditional E-value: 8.6e-111
                                     EEEECSSTTEEEEETTSSEEEEEE-SSTT--SSSSEEEEETTE........EEEEE-TTTSHHHHHHHTT-S--S--TT CS
                     Fibrillarin   1 veeheklegvyivkekgdarlatknlvpgekvYgEklikveee........EyRvWnpfrsKlaaailkglkelpikkg 71 
                                     +e+h ++egv+i+++k+da l+tkn+vpge++YgEk+i+ve+         EyRvWnpfrsKlaaail g+++++i +g
  tr|A0A1X7UZ07|A0A1X7UZ07_AMPQE   9 IEPH-RHEGVFICRGKEDA-LVTKNMVPGEAIYGEKRISVESGvegstdkvEYRVWNPFRSKLAAAILGGVDNIHIGPG 85 
                                     5788.9**********999.********************9999999******************************** PP

                                     SEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSHHHHHHHHHHHTTSTTEEEEES-TTSGGGGTTTS--EEEEEEESSS CS
                     Fibrillarin  72 skvLYlGaasGttvsHvsDivgeegvvyavefsprvlrelievakkRknivPileDArkPekYralvekvDvifaDvaq 150
                                     skvLYlGaasGttvsHvsDivg++g+vyavefs+r++r+li+vakkR+ni+Pi+eDAr+P+kYr+l+ +vD+ifaDvaq
  tr|A0A1X7UZ07|A0A1X7UZ07_AMPQE  86 SKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINVAKKRTNIIPIIEDARHPHKYRMLMGMVDTIFADVAQ 164
                                     ******************************************************************************* PP

                                     TTHHHHHHHHHHHHEEEEEEEEEEEEHHHHHSSSSHHHHHHHHHHHHHHTTEEEEEEEE-TTTSTTEEEEEEEEE CS
                     Fibrillarin 151 pdqarilaknaklflkeggyllisikarsidvtkepeevfkeeveklkeeglkvleqvklepyekdhalvvgkyk 225
                                     pdqari+  na +flk++g+++isika++id+t+ep++vf+ ev+kl+ ++l+++eq++lepye+dha+vvg+++
  tr|A0A1X7UZ07|A0A1X7UZ07_AMPQE 165 PDQARIVGINALHFLKNQGHFVISIKANCIDSTAEPTKVFAGEVKKLQADNLRPKEQITLEPYERDHAVVVGVFR 239
                                     ***********************************************************************9875 PP

>> tr|A0A1X7V969|A0A1X7V969_AMPQE  Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.0   0.0   1.4e-09     1e-05      62     145 ..      21     105 ..      16     115 .. 0.84
   2 ?   -0.6   0.0       0.2   1.5e+03     126     151 ..     159     186 ..     149     199 .. 0.71

  Alignments for each domain:
  == domain 1  score: 26.0 bits;  conditional E-value: 1.4e-09
                                     T-S--S--TTSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSHHHHHHHHHHHTTSTTEEEEES.-TTSGGGGT.TTS CS
                     Fibrillarin  62 glkelpikkgskvLYlGaasGttvsHvsDivgeegvvyavefsprvlrelievakkRknivPile.DArkPekYr.alv 138
                                      ++e+ +k+g++vL lG ++G  +  +s ivgeeg+v av+  +  + el + +++  ni  +++ DA +P++ + + v
  tr|A0A1X7V969|A0A1X7V969_AMPQE  21 LIEEISVKEGDHVLDLGCGTGHLAVVLSKIVGEEGKVIAVDPNNERI-ELAKEVNSSINIEYLVAsDADFPTDQQyHSV 98 
                                     57899************************************877654.899999999999887744*****64331456 PP

                                     --EEEEE CS
                     Fibrillarin 139 ekvDvif 145
                                      + Dvi+
  tr|A0A1X7V969|A0A1X7V969_AMPQE  99 ICTDVIH 105
                                     6778875 PP

  == domain 2  score: -0.6 bits;  conditional E-value: 0.2
                                     S-TTSGGGGTTTS-..-EEEEEEESSST CS
                     Fibrillarin 126 eDArkPekYralve..kvDvifaDvaqp 151
                                      +  +PekY++l +    +v f+Dv ++
  tr|A0A1X7V969|A0A1X7V969_AMPQE 159 YNTLTPEKYKELASltGFEVTFMDVFEA 186
                                     5566899999997633679999999654 PP

>> tr|A0A1X7VEF1|A0A1X7VEF1_AMPQE  Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.3   0.0   6.6e-07    0.0048      64     144 ..      25     107 ..      18     133 .. 0.83

  Alignments for each domain:
  == domain 1  score: 17.3 bits;  conditional E-value: 6.6e-07
                                     S--S--TTSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSHHHHHHHH.HHHTTSTTEEEEES-.TTSGGGGTTTS-- CS
                     Fibrillarin  64 kelpikkgskvLYlGaasGttvsHvsDivgeegvvyavefsprvlreli.evakkRknivPileD.ArkPekYralvek 140
                                     +el  ++ +kvL lG ++G+    +++ vg+eg+v +++  +  ++  i e  + R+n++ +++D  ++Pe+   +v +
  tr|A0A1X7VEF1|A0A1X7VEF1_AMPQE  25 EELSPQEKDKVLDLGCGTGRLTQVLAERVGPEGLVVGIDPDEERIKVAIeEKGHGRSNLIFVVADdQSFPEDQYDMVFC 103
                                     566678899******************************9887777666377899****99997615689876666666 PP

                                     EEEE CS
                     Fibrillarin 141 vDvi 144
                                      +vi
  tr|A0A1X7VEF1|A0A1X7VEF1_AMPQE 104 SNVI 107
                                     6666 PP

>> tr|A0A1X7V2C8|A0A1X7V2C8_AMPQE  Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.1   0.0   1.3e-05     0.092      61     145 ..      34     119 ..      29     169 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.1 bits;  conditional E-value: 1.3e-05
                                     TT-S--S--TTSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSHHHHH.HHHHHHTTSTTE.EEEES-TTSGGGGTTT CS
                     Fibrillarin  61 kglkelpikkgskvLYlGaasGttvsHvsDivgeegvvyavefsprvlr.elievakkRkni.vPileDArkPekYral 137
                                     k lk+lpi++ + vL lG ++G+  s ++  v  +g+v +++  +  ++  + e + + + + + i  D ++Pe+    
  tr|A0A1X7V2C8|A0A1X7V2C8_AMPQE  34 KLLKKLPIQETDVVLDLGCGTGRLTSNIAKRVI-NGKVIGIDPDEERIKiAMAESTGDSTSLqFMIASDQSFPENQYDH 111
                                     55899*************************998.9******98765555155555555555525677899999865555 PP

                                     S--EEEEE CS
                     Fibrillarin 138 vekvDvif 145
                                     v + Dvi+
  tr|A0A1X7V2C8|A0A1X7V2C8_AMPQE 112 VVSTDVIH 119
                                     55678875 PP

>> tr|A0A1X7VHW4|A0A1X7VHW4_AMPQE  Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    9.9   0.0   0.00012       0.9      71     142 ..      29     101 ..      14     111 .. 0.86
   2 ?   -1.7   0.0      0.44   3.2e+03     115     125 ..     183     193 ..     158     203 .. 0.72

  Alignments for each domain:
  == domain 1  score: 9.9 bits;  conditional E-value: 0.00012
                                     TSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSHHHHHHHHHHHTTSTTEEEEES.-TTSGG.GGTTTS--EE CS
                     Fibrillarin  71 gskvLYlGaasGttvsHvsDivgeegvvyavefsprvlrelievakkRknivPile.DArkPe.kYralvekvD 142
                                     ++kvL +G ++G+    +s  vg+ g+v +v+  +  ++  i+  k  +ni  +++ D ++Pe kY a+v+  D
  tr|A0A1X7VHW4|A0A1X7VHW4_AMPQE  29 NEKVLDIGCGTGRLSKVISKRVGNGGKVIGVDPDEERIKIAINERKGYNNIQFMVGsDQTFPEdKYDAIVS-TD 101
                                     689************************************************98885499999735776664.44 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 0.44
                                     HTTSTTEEEEE CS
                     Fibrillarin 115 akkRknivPil 125
                                     +k Rkni+P l
  tr|A0A1X7VHW4|A0A1X7VHW4_AMPQE 183 VKARKNIFPNL 193
                                     57788888866 PP

>> tr|A0A1X7UXG8|A0A1X7UXG8_AMPQE  Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.1   0.0      0.14   9.9e+02     107     125 ..     731     749 ..     726     756 .. 0.85
   2 ?    7.8   0.1   0.00055       3.9      80     103 ..    1327    1350 ..    1323    1357 .. 0.87

  Alignments for each domain:
  == domain 1  score: -0.1 bits;  conditional E-value: 0.14
                                     HHHHHHHHHTTSTTEEEEE CS
                     Fibrillarin 107 vlrelievakkRknivPil 125
                                     +l++li ++++ +n++Pi 
  tr|A0A1X7UXG8|A0A1X7UXG8_AMPQE 731 SLQDLILICDSHTNLIPIA 749
                                     5799*************95 PP

  == domain 2  score: 7.8 bits;  conditional E-value: 0.00055
                                      TTSHHHHHHHHHHTTTSEEEEEES CS
                     Fibrillarin   80 asGttvsHvsDivgeegvvyavef 103 
                                      +s  t sHvsD +++++++ya e 
  tr|A0A1X7UXG8|A0A1X7UXG8_AMPQE 1327 SSDVTESHVSDTIHKTAIIYAHEL 1350
                                      7889*****************886 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (226 nodes)
Target sequences:                        43435  (14716620 residues searched)
Passed MSV filter:                      1100  (0.0253252); expected 868.7 (0.02)
Passed bias filter:                      781  (0.0179809); expected 868.7 (0.02)
Passed Vit filter:                        56  (0.00128928); expected 43.4 (0.001)
Passed Fwd filter:                         6  (0.000138137); expected 0.4 (1e-05)
Initial search space (Z):              43435  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.24u 0.01s 00:00:00.25 Elapsed: 00:00:00.11
# Mc/sec: 30235.96
//
[ok]