# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Fibrillarin.hmm.txt
# target sequence database: proteomes/Caenorhabditis_elegans.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Fibrillarin [M=226]
Accession: PF01269.17
Description: Fibrillarin
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
9.3e-108 358.7 0.0 1.2e-107 358.4 0.0 1.0 1 sp|Q22053|FBRL_CAEEL rRNA 2'-O-methyltransferase fibrillar
------ inclusion threshold ------
0.036 13.3 0.0 0.15 11.3 0.0 1.9 2 tr|Q9NAA7|Q9NAA7_CAEEL Nop2 (NOP2)/SUN domain family member
0.046 13.0 0.0 0.09 12.0 0.0 1.5 1 sp|Q27873|PIMT_CAEEL Protein-L-isoaspartate O-methyltransf
Domain annotation for each sequence (and alignments):
>> sp|Q22053|FBRL_CAEEL rRNA 2'-O-methyltransferase fibrillarin OS=Caenorhabditis elegans OX=6239 GN=fib-1 PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 358.4 0.0 1.7e-111 1.2e-107 1 225 [. 119 345 .. 119 346 .. 0.99
Alignments for each domain:
== domain 1 score: 358.4 bits; conditional E-value: 1.7e-111
EEEECSSTTEEEEETTSSEEEEEE-SSTT--SSSSEEEEETTE....EEEEE-TTTSHHHHHHHTT-S--S--TTSEEEEESTTTSHHH CS
Fibrillarin 1 veeheklegvyivkekgdarlatknlvpgekvYgEklikveee....EyRvWnpfrsKlaaailkglkelpikkgskvLYlGaasGttv 85
ve+h +l gv+ivk+k+da latkn+v ge+vYgEk+++v++ EyRvWnpfrsKlaa+i+ gl++++ik+g+k+LYlGaasGttv
sp|Q22053|FBRL_CAEEL 119 VEPH-RLGGVFIVKGKEDA-LATKNMVVGESVYGEKRVSVDDGagsiEYRVWNPFRSKLAASIMGGLENTHIKPGTKLLYLGAASGTTV 205
5788.99*********999.*********************99999******************************************* PP
HHHHHHHTTTSEEEEEESSHHHHHHHHHHHTTSTTEEEEES-TTSGGGGTTTS--EEEEEEESSSTTHHHHHHHHHHHHEEEEEEEEEE CS
Fibrillarin 86 sHvsDivgeegvvyavefsprvlrelievakkRknivPileDArkPekYralvekvDvifaDvaqpdqarilaknaklflkeggyllis 174
sH+sD+vg+eg+vyavefs+r++r+l+ vakkR+n+vPi+eDAr+P+kYr+lv +vDvif+Dvaqpdqari+a+na+ fl++gg+ +is
sp|Q22053|FBRL_CAEEL 206 SHCSDVVGPEGIVYAVEFSHRSGRDLLGVAKKRPNVVPIVEDARHPHKYRMLVGMVDVIFSDVAQPDQARIVALNAQNFLRNGGHAVIS 294
***************************************************************************************** PP
EEHHHHHSSSSHHHHHHHHHHHHHHTTEEEEEEEE-TTTSTTEEEEEEEEE CS
Fibrillarin 175 ikarsidvtkepeevfkeeveklkeeglkvleqvklepyekdhalvvgkyk 225
ika++id+t+epe+vf+ ev+klkee++k+leqv+lepye+dha+vv++y+
sp|Q22053|FBRL_CAEEL 295 IKANCIDSTAEPEAVFAGEVNKLKEEKFKPLEQVTLEPYERDHAVVVAVYR 345
************************************************997 PP
>> tr|Q9NAA7|Q9NAA7_CAEEL Nop2 (NOP2)/SUN domain family member OS=Caenorhabditis elegans OX=6239 GN=nsun-5 PE=1 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -1.1 0.0 0.14 9.4e+02 130 179 .. 170 224 .. 165 231 .. 0.67
2 ? 11.3 0.0 2.2e-05 0.15 69 112 .. 233 279 .. 222 285 .. 0.81
Alignments for each domain:
== domain 1 score: -1.1 bits; conditional E-value: 0.14
SGGGGTTTS--E..EEEEEESSSTTHHHHHHHHHHHH....EEEEEEEEEEEEHHH CS
Fibrillarin 130 kPekYralvekv..DvifaDvaqpdqarilaknaklf....lkeggyllisikars 179
kPe+++++v+k+ D +++D + ++ i+a n + f + e+ yl+++ ka++
tr|Q9NAA7|Q9NAA7_CAEEL 170 KPENFAEMVTKMkdDEVYVD-PHVENLIIFAPNIQNFyeywMVEQRYLILQDKASC 224
79999999984434899999.55666678887876551111556667777667666 PP
== domain 2 score: 11.3 bits; conditional E-value: 2.2e-05
-TTSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSH.H..HHHHHH CS
Fibrillarin 69 kkgskvLYlGaasGttvsHvsDivgeegvvyavefsp.r..vlreli 112
++gs+v aa G sH + i++++g+v+a++ + r ++++l+
tr|Q9NAA7|Q9NAA7_CAEEL 233 RPGSQVFDTCAAPGMKTSHAAAIMENQGKVWAMDRAAdRvaTMKQLL 279
68999999*************************98651311355555 PP
>> sp|Q27873|PIMT_CAEEL Protein-L-isoaspartate O-methyltransferase OS=Caenorhabditis elegans OX=6239 GN=pcm-1 PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.0 0.0 1.4e-05 0.09 65 128 .. 73 143 .. 60 152 .. 0.72
Alignments for each domain:
== domain 1 score: 12.0 bits; conditional E-value: 1.4e-05
--S--TTSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSHHHH.......HHHHHHHTTSTTEEEEES-T CS
Fibrillarin 65 elpikkgskvLYlGaasGttvsHvsDivgeegvvyavefsprvl.......relievakkRknivPileDA 128
+ ++ g+k L +G++sG ++ +vg++g+v ++e+ p+ + r+ + +R n++ i +D
sp|Q27873|PIMT_CAEEL 73 QNHLVAGAKALDVGSGSGYLTVCMAMMVGRNGTVVGIEHMPQLVelsekniRKHHSEQLERGNVIIIEGDG 143
468899******************************98876543111100055555555666666666665 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (226 nodes)
Target sequences: 20008 (8229220 residues searched)
Passed MSV filter: 524 (0.0261895); expected 400.2 (0.02)
Passed bias filter: 384 (0.0191923); expected 400.2 (0.02)
Passed Vit filter: 31 (0.00154938); expected 20.0 (0.001)
Passed Fwd filter: 3 (0.00014994); expected 0.2 (1e-05)
Initial search space (Z): 20008 [actual number of targets]
Domain search space (domZ): 3 [number of targets reported over threshold]
# CPU time: 0.14u 0.01s 00:00:00.15 Elapsed: 00:00:00.06
# Mc/sec: 30996.73
//
[ok]