# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Fibrillarin.hmm.txt
# target sequence database: proteomes/Ciona_intestinalis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Fibrillarin [M=226]
Accession: PF01269.17
Description: Fibrillarin
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
1.9e-108 360.7 0.0 2.2e-108 360.5 0.0 1.0 1 tr|F7A5J2|F7A5J2_CIOIN rRNA 2'-O-methyltransferase fibrillar
------ inclusion threshold ------
0.026 13.6 0.0 0.047 12.7 0.0 1.4 1 tr|H2XZ35|H2XZ35_CIOIN Uncharacterized protein OS=Ciona inte
0.036 13.1 0.0 0.077 12.0 0.0 1.5 1 tr|F6YD46|F6YD46_CIOIN Uncharacterized protein OS=Ciona inte
0.056 12.4 0.0 0.08 11.9 0.0 1.2 1 tr|F6T569|F6T569_CIOIN Uncharacterized protein OS=Ciona inte
0.06 12.3 0.0 0.18 10.8 0.0 1.7 2 tr|F6ZIX6|F6ZIX6_CIOIN Uncharacterized protein OS=Ciona inte
0.12 11.3 0.0 0.51 9.3 0.0 1.8 1 tr|H2XSX6|H2XSX6_CIOIN tRNA (adenine(58)-N(1))-methyltransfe
Domain annotation for each sequence (and alignments):
>> tr|F7A5J2|F7A5J2_CIOIN rRNA 2'-O-methyltransferase fibrillarin isoform X1 OS=Ciona intestinalis OX=7719 GN=LOC100186
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 360.5 0.0 8e-112 2.2e-108 1 225 [. 75 301 .. 75 302 .. 0.99
Alignments for each domain:
== domain 1 score: 360.5 bits; conditional E-value: 8e-112
EEEECSSTTEEEEETTSSEEEEEE-SSTT--SSSSEEEEETTE....EEEEE-TTTSHHHHHHHTT-S--S--TTSEEEEESTTTSH CS
Fibrillarin 1 veeheklegvyivkekgdarlatknlvpgekvYgEklikveee....EyRvWnpfrsKlaaailkglkelpikkgskvLYlGaasGt 83
ve+h +++g++i+++k+da l+tknlvpg +vYgEk i+ve e EyR WnpfrsKlaaa+l g++ ++ik+gskvLYlGaasGt
tr|F7A5J2|F7A5J2_CIOIN 75 VEPH-RHSGIFIARGKEDA-LVTKNLVPGDTVYGEKKIEVELEgaktEYRAWNPFRSKLAAAVLGGIEAIHIKPGSKVLYLGAASGT 159
6788.9**********999.********************9989999**************************************** PP
HHHHHHHHHTTTSEEEEEESSHHHHHHHHHHHTTSTTEEEEES-TTSGGGGTTTS--EEEEEEESSSTTHHHHHHHHHHHHEEEEEE CS
Fibrillarin 84 tvsHvsDivgeegvvyavefsprvlrelievakkRknivPileDArkPekYralvekvDvifaDvaqpdqarilaknaklflkeggy 170
tvsHvsDivg+eg+vyavefs+r++r+li+vakkR+ni+Pi+eDAr+P+kYr+lv +vD+ifaDvaqpdq+ri+a+na++flk+ g+
tr|F7A5J2|F7A5J2_CIOIN 160 TVSHVSDIVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPIIEDARHPHKYRMLVGMVDTIFADVAQPDQTRIVALNAHHFLKNTGH 246
*************************************************************************************** PP
EEEEEEHHHHHSSSSHHHHHHHHHHHHHHTTEEEEEEEE-TTTSTTEEEEEEEEE CS
Fibrillarin 171 llisikarsidvtkepeevfkeeveklkeeglkvleqvklepyekdhalvvgkyk 225
++isika++id+t++pe+vf++ev+k++ e++k++eq++lepye+dha+vvg y+
tr|F7A5J2|F7A5J2_CIOIN 247 FVISIKASCIDSTAKPEAVFASEVKKMQGEKMKPQEQMTLEPYERDHAVVVGIYR 301
****************************************************996 PP
>> tr|H2XZ35|H2XZ35_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.7 0.0 1.7e-05 0.047 70 108 .. 213 251 .. 204 269 .. 0.83
Alignments for each domain:
== domain 1 score: 12.7 bits; conditional E-value: 1.7e-05
TTSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSHHHH CS
Fibrillarin 70 kgskvLYlGaasGttvsHvsDivgeegvvyavefsprvl 108
++s+v+ aa G sH+s i++++g+++a++ s+ +
tr|H2XZ35|H2XZ35_CIOIN 213 PNSHVIDACAAPGNKTSHLSAIMNNTGKLFAIDRSSERI 251
678899999***********************9987544 PP
>> tr|F6YD46|F6YD46_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.0 0.0 2.8e-05 0.077 71 155 .. 113 203 .. 99 223 .. 0.77
Alignments for each domain:
== domain 1 score: 12.0 bits; conditional E-value: 2.8e-05
TSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSH...HHHHHHHHHH..TTSTTEEEEES-TTSGGGGT.TTS--EEEEEEESSST CS
Fibrillarin 71 gskvLYlGaasGttvsHvsDivgeegvvyavefsp...rvlrelieva..kkRknivPileDArkPekYr.alvekvDvifaDvaqp 151
++vL lG G + +s +++e+++++++e p + +++i+ a +kR i+ l D P+ + v++ D +f D a+
tr|F6YD46|F6YD46_CIOIN 113 PQNVLELGCYCGYSSLRMSRLLKEDAKIFTIEANPdyaKFAQQIITFAgmEKRIQILQGLSDEVLPTIAEkCGVQTFDFVFIDHAKE 199
478*****************************99832245678887654489999***********97651569*********9987 PP
THHH CS
Fibrillarin 152 dqar 155
r
tr|F6YD46|F6YD46_CIOIN 200 LYKR 203
5444 PP
>> tr|F6T569|F6T569_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.9 0.0 2.9e-05 0.08 71 157 .. 61 153 .. 46 172 .. 0.76
Alignments for each domain:
== domain 1 score: 11.9 bits; conditional E-value: 2.9e-05
TSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSHH...HHHHHHHHH..TTSTTEEEEES-TTSGGGGT.TTS--EEEEEEESSST CS
Fibrillarin 71 gskvLYlGaasGttvsHvsDivgeegvvyavefspr...vlrelieva..kkRknivPileDArkPekYr.alvekvDvifaDvaqp 151
++vL +G G ++ +s +++e+++++++e s++ v +e+i+ a +k+ i+ l D P+ + v++ D +f D a+
tr|F6T569|F6T569_CIOIN 61 PKNVLEIGCYCGYSALRMSRLLKEDAKIFTIEASSQyadVAQEIISFAgmEKKVQILRGLSDEVLPTIAEkCGVRTFDFVFIDHAKE 147
478*****************************99863336899998863366777888899*****976515699********9987 PP
THHHHH CS
Fibrillarin 152 dqaril 157
r l
tr|F6T569|F6T569_CIOIN 148 LYKRDL 153
555433 PP
>> tr|F6ZIX6|F6ZIX6_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 GN=LOC100181209 PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 10.8 0.0 6.3e-05 0.18 70 106 .. 71 107 .. 63 122 .. 0.89
2 ? -2.1 0.0 0.55 1.5e+03 170 198 .. 147 175 .. 143 197 .. 0.75
Alignments for each domain:
== domain 1 score: 10.8 bits; conditional E-value: 6.3e-05
TTSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSHH CS
Fibrillarin 70 kgskvLYlGaasGttvsHvsDivgeegvvyavefspr 106
+g k+L lG +sG+ +s +vge+g v +v++++
tr|F6ZIX6|F6ZIX6_CIOIN 71 EGVKILDLGCGSGRDCYVMSQLVGEDGYVTGVDMTKE 107
699*****************************98865 PP
== domain 2 score: -2.1 bits; conditional E-value: 0.55
EEEEEEEHHHHHSSSSHHHHHHHHHHHHH CS
Fibrillarin 170 yllisikarsidvtkepeevfkeeveklk 198
+ i+i ++ ++ e+v+ke + lk
tr|F6ZIX6|F6ZIX6_CIOIN 147 SIDIAISNCVVNLCEDKESVYKEVYRVLK 175
55677777777888888888888877776 PP
>> tr|H2XSX6|H2XSX6_CIOIN tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A OS=Ciona intestinalis OX=
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 9.3 0.0 0.00018 0.51 57 184 .. 88 212 .. 74 234 .. 0.70
Alignments for each domain:
== domain 1 score: 9.3 bits; conditional E-value: 0.00018
HHHHTT-S--S--TTSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSH.HHHHHHHHHHTTSTTEEEEES-TTSGGGGTTTS-.-E CS
Fibrillarin 57 aailkglkelpikkgskvLYlGaasGttvsHvsDivgeegvvyavefsp.rvlrelievakkRknivPileDArkPekYralve.kv 141
a i l +l +k+gs v G++sG+ + + ++g +++vef + r+ + +e k+ + + + r k v+
tr|H2XSX6|H2XSX6_CIOIN 88 ADISMILFQLDLKPGSVVCESGTGSGSLSHAIIRTIAPTGFLHTVEFHEdRANKASLEFKKHGLADYVTVYN-RDVIKLGFPVTsVA 173
566777788999*************9876668899999********97526666666666554433333333.44444444444267 PP
EEEEEESSSTTHHHHHHHHHHHHEEEEEEEEEEEEHHHHHSSS CS
Fibrillarin 142 DvifaDvaqpdqarilaknaklflkeggyllisikarsidvtk 184
D +f D+ pd a +a na lk+ g l s + +i+ ++
tr|H2XSX6|H2XSX6_CIOIN 174 DAVFLDIPSPDDAISAAANA---LKQSGGRLCSF-SPCIEQVQ 212
99999999999998888887...67766666554.45665555 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (226 nodes)
Target sequences: 16678 (5370518 residues searched)
Passed MSV filter: 381 (0.0228445); expected 333.6 (0.02)
Passed bias filter: 264 (0.0158292); expected 333.6 (0.02)
Passed Vit filter: 19 (0.00113923); expected 16.7 (0.001)
Passed Fwd filter: 6 (0.000359755); expected 0.2 (1e-05)
Initial search space (Z): 16678 [actual number of targets]
Domain search space (domZ): 6 [number of targets reported over threshold]
# CPU time: 0.11u 0.01s 00:00:00.12 Elapsed: 00:00:00.04
# Mc/sec: 30343.43
//
[ok]