# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Fibrillarin.hmm.txt # target sequence database: proteomes/Ciona_intestinalis.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Fibrillarin [M=226] Accession: PF01269.17 Description: Fibrillarin Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.9e-108 360.7 0.0 2.2e-108 360.5 0.0 1.0 1 tr|F7A5J2|F7A5J2_CIOIN rRNA 2'-O-methyltransferase fibrillar ------ inclusion threshold ------ 0.026 13.6 0.0 0.047 12.7 0.0 1.4 1 tr|H2XZ35|H2XZ35_CIOIN Uncharacterized protein OS=Ciona inte 0.036 13.1 0.0 0.077 12.0 0.0 1.5 1 tr|F6YD46|F6YD46_CIOIN Uncharacterized protein OS=Ciona inte 0.056 12.4 0.0 0.08 11.9 0.0 1.2 1 tr|F6T569|F6T569_CIOIN Uncharacterized protein OS=Ciona inte 0.06 12.3 0.0 0.18 10.8 0.0 1.7 2 tr|F6ZIX6|F6ZIX6_CIOIN Uncharacterized protein OS=Ciona inte 0.12 11.3 0.0 0.51 9.3 0.0 1.8 1 tr|H2XSX6|H2XSX6_CIOIN tRNA (adenine(58)-N(1))-methyltransfe Domain annotation for each sequence (and alignments): >> tr|F7A5J2|F7A5J2_CIOIN rRNA 2'-O-methyltransferase fibrillarin isoform X1 OS=Ciona intestinalis OX=7719 GN=LOC100186 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 360.5 0.0 8e-112 2.2e-108 1 225 [. 75 301 .. 75 302 .. 0.99 Alignments for each domain: == domain 1 score: 360.5 bits; conditional E-value: 8e-112 EEEECSSTTEEEEETTSSEEEEEE-SSTT--SSSSEEEEETTE....EEEEE-TTTSHHHHHHHTT-S--S--TTSEEEEESTTTSH CS Fibrillarin 1 veeheklegvyivkekgdarlatknlvpgekvYgEklikveee....EyRvWnpfrsKlaaailkglkelpikkgskvLYlGaasGt 83 ve+h +++g++i+++k+da l+tknlvpg +vYgEk i+ve e EyR WnpfrsKlaaa+l g++ ++ik+gskvLYlGaasGt tr|F7A5J2|F7A5J2_CIOIN 75 VEPH-RHSGIFIARGKEDA-LVTKNLVPGDTVYGEKKIEVELEgaktEYRAWNPFRSKLAAAVLGGIEAIHIKPGSKVLYLGAASGT 159 6788.9**********999.********************9989999**************************************** PP HHHHHHHHHTTTSEEEEEESSHHHHHHHHHHHTTSTTEEEEES-TTSGGGGTTTS--EEEEEEESSSTTHHHHHHHHHHHHEEEEEE CS Fibrillarin 84 tvsHvsDivgeegvvyavefsprvlrelievakkRknivPileDArkPekYralvekvDvifaDvaqpdqarilaknaklflkeggy 170 tvsHvsDivg+eg+vyavefs+r++r+li+vakkR+ni+Pi+eDAr+P+kYr+lv +vD+ifaDvaqpdq+ri+a+na++flk+ g+ tr|F7A5J2|F7A5J2_CIOIN 160 TVSHVSDIVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPIIEDARHPHKYRMLVGMVDTIFADVAQPDQTRIVALNAHHFLKNTGH 246 *************************************************************************************** PP EEEEEEHHHHHSSSSHHHHHHHHHHHHHHTTEEEEEEEE-TTTSTTEEEEEEEEE CS Fibrillarin 171 llisikarsidvtkepeevfkeeveklkeeglkvleqvklepyekdhalvvgkyk 225 ++isika++id+t++pe+vf++ev+k++ e++k++eq++lepye+dha+vvg y+ tr|F7A5J2|F7A5J2_CIOIN 247 FVISIKASCIDSTAKPEAVFASEVKKMQGEKMKPQEQMTLEPYERDHAVVVGIYR 301 ****************************************************996 PP >> tr|H2XZ35|H2XZ35_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.0 1.7e-05 0.047 70 108 .. 213 251 .. 204 269 .. 0.83 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 1.7e-05 TTSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSHHHH CS Fibrillarin 70 kgskvLYlGaasGttvsHvsDivgeegvvyavefsprvl 108 ++s+v+ aa G sH+s i++++g+++a++ s+ + tr|H2XZ35|H2XZ35_CIOIN 213 PNSHVIDACAAPGNKTSHLSAIMNNTGKLFAIDRSSERI 251 678899999***********************9987544 PP >> tr|F6YD46|F6YD46_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.0 0.0 2.8e-05 0.077 71 155 .. 113 203 .. 99 223 .. 0.77 Alignments for each domain: == domain 1 score: 12.0 bits; conditional E-value: 2.8e-05 TSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSH...HHHHHHHHHH..TTSTTEEEEES-TTSGGGGT.TTS--EEEEEEESSST CS Fibrillarin 71 gskvLYlGaasGttvsHvsDivgeegvvyavefsp...rvlrelieva..kkRknivPileDArkPekYr.alvekvDvifaDvaqp 151 ++vL lG G + +s +++e+++++++e p + +++i+ a +kR i+ l D P+ + v++ D +f D a+ tr|F6YD46|F6YD46_CIOIN 113 PQNVLELGCYCGYSSLRMSRLLKEDAKIFTIEANPdyaKFAQQIITFAgmEKRIQILQGLSDEVLPTIAEkCGVQTFDFVFIDHAKE 199 478*****************************99832245678887654489999***********97651569*********9987 PP THHH CS Fibrillarin 152 dqar 155 r tr|F6YD46|F6YD46_CIOIN 200 LYKR 203 5444 PP >> tr|F6T569|F6T569_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 2.9e-05 0.08 71 157 .. 61 153 .. 46 172 .. 0.76 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 2.9e-05 TSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSHH...HHHHHHHHH..TTSTTEEEEES-TTSGGGGT.TTS--EEEEEEESSST CS Fibrillarin 71 gskvLYlGaasGttvsHvsDivgeegvvyavefspr...vlrelieva..kkRknivPileDArkPekYr.alvekvDvifaDvaqp 151 ++vL +G G ++ +s +++e+++++++e s++ v +e+i+ a +k+ i+ l D P+ + v++ D +f D a+ tr|F6T569|F6T569_CIOIN 61 PKNVLEIGCYCGYSALRMSRLLKEDAKIFTIEASSQyadVAQEIISFAgmEKKVQILRGLSDEVLPTIAEkCGVRTFDFVFIDHAKE 147 478*****************************99863336899998863366777888899*****976515699********9987 PP THHHHH CS Fibrillarin 152 dqaril 157 r l tr|F6T569|F6T569_CIOIN 148 LYKRDL 153 555433 PP >> tr|F6ZIX6|F6ZIX6_CIOIN Uncharacterized protein OS=Ciona intestinalis OX=7719 GN=LOC100181209 PE=4 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 6.3e-05 0.18 70 106 .. 71 107 .. 63 122 .. 0.89 2 ? -2.1 0.0 0.55 1.5e+03 170 198 .. 147 175 .. 143 197 .. 0.75 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 6.3e-05 TTSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSHH CS Fibrillarin 70 kgskvLYlGaasGttvsHvsDivgeegvvyavefspr 106 +g k+L lG +sG+ +s +vge+g v +v++++ tr|F6ZIX6|F6ZIX6_CIOIN 71 EGVKILDLGCGSGRDCYVMSQLVGEDGYVTGVDMTKE 107 699*****************************98865 PP == domain 2 score: -2.1 bits; conditional E-value: 0.55 EEEEEEEHHHHHSSSSHHHHHHHHHHHHH CS Fibrillarin 170 yllisikarsidvtkepeevfkeeveklk 198 + i+i ++ ++ e+v+ke + lk tr|F6ZIX6|F6ZIX6_CIOIN 147 SIDIAISNCVVNLCEDKESVYKEVYRVLK 175 55677777777888888888888877776 PP >> tr|H2XSX6|H2XSX6_CIOIN tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A OS=Ciona intestinalis OX= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.3 0.0 0.00018 0.51 57 184 .. 88 212 .. 74 234 .. 0.70 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 0.00018 HHHHTT-S--S--TTSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSH.HHHHHHHHHHTTSTTEEEEES-TTSGGGGTTTS-.-E CS Fibrillarin 57 aailkglkelpikkgskvLYlGaasGttvsHvsDivgeegvvyavefsp.rvlrelievakkRknivPileDArkPekYralve.kv 141 a i l +l +k+gs v G++sG+ + + ++g +++vef + r+ + +e k+ + + + r k v+ tr|H2XSX6|H2XSX6_CIOIN 88 ADISMILFQLDLKPGSVVCESGTGSGSLSHAIIRTIAPTGFLHTVEFHEdRANKASLEFKKHGLADYVTVYN-RDVIKLGFPVTsVA 173 566777788999*************9876668899999********97526666666666554433333333.44444444444267 PP EEEEEESSSTTHHHHHHHHHHHHEEEEEEEEEEEEHHHHHSSS CS Fibrillarin 142 DvifaDvaqpdqarilaknaklflkeggyllisikarsidvtk 184 D +f D+ pd a +a na lk+ g l s + +i+ ++ tr|H2XSX6|H2XSX6_CIOIN 174 DAVFLDIPSPDDAISAAANA---LKQSGGRLCSF-SPCIEQVQ 212 99999999999998888887...67766666554.45665555 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (226 nodes) Target sequences: 16678 (5370518 residues searched) Passed MSV filter: 381 (0.0228445); expected 333.6 (0.02) Passed bias filter: 264 (0.0158292); expected 333.6 (0.02) Passed Vit filter: 19 (0.00113923); expected 16.7 (0.001) Passed Fwd filter: 6 (0.000359755); expected 0.2 (1e-05) Initial search space (Z): 16678 [actual number of targets] Domain search space (domZ): 6 [number of targets reported over threshold] # CPU time: 0.11u 0.01s 00:00:00.12 Elapsed: 00:00:00.04 # Mc/sec: 30343.43 // [ok]