# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Fibrillarin.hmm.txt
# target sequence database: proteomes/Dictyostelium_discoideum.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Fibrillarin [M=226]
Accession: PF01269.17
Description: Fibrillarin
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
7.7e-102 338.7 0.0 8.9e-102 338.5 0.0 1.0 1 sp|Q55CW0|FBRL_DICDI rRNA 2'-O-methyltransferase fibrillar
9e-05 21.2 0.2 0.00012 20.7 0.2 1.2 1 tr|Q54LU3|Q54LU3_DICDI Uncharacterized protein OS=Dictyostel
0.0064 15.1 0.0 0.011 14.4 0.0 1.3 1 tr|Q55GM3|Q55GM3_DICDI Uncharacterized protein OS=Dictyostel
0.007 15.0 0.1 0.01 14.5 0.1 1.3 1 tr|Q54KV1|Q54KV1_DICDI Uncharacterized protein OS=Dictyostel
------ inclusion threshold ------
0.012 14.2 0.1 0.019 13.6 0.1 1.2 1 tr|Q54F82|Q54F82_DICDI Uncharacterized protein OS=Dictyostel
Domain annotation for each sequence (and alignments):
>> sp|Q55CW0|FBRL_DICDI rRNA 2'-O-methyltransferase fibrillarin OS=Dictyostelium discoideum OX=44689 GN=fbl PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 338.5 0.0 3.5e-105 8.9e-102 1 225 [. 99 327 .. 99 328 .. 0.98
Alignments for each domain:
== domain 1 score: 338.5 bits; conditional E-value: 3.5e-105
EEEECSSTTEEEEETTSSEEEEEE-SSTT--SSSSEEEEETTE....EEEEE-TTTSHHHHHHHTT-S--S--TTSEEEEESTTTSHHH CS
Fibrillarin 1 veeheklegvyivkekgdarlatknlvpgekvYgEklikveee....EyRvWnpfrsKlaaailkglkelpikkgskvLYlGaasGttv 85
ve+h ++egv+iv++k+++ lat n vpge+vYgEk+++v+e EyR+WnpfrsK+aa++++g++e++ik+gskvLY+GaasGtt+
sp|Q55CW0|FBRL_DICDI 99 VEKHPRHEGVFIVRGKEES-LATLNSVPGESVYGEKRVSVGEGedkkEYRIWNPFRSKIAAGLHRGVDEIHIKPGSKVLYIGAASGTTI 186
689************9999.*******************98766778****************************************** PP
HHHHHHHTTTSEEEEEESSHHHHHHHHHHHTTSTTEEEEES-TTSGGGGTTTS--EEEEEEESSSTTHHHHHHHHHHHHEEEEEEEEEE CS
Fibrillarin 86 sHvsDivgeegvvyavefsprvlrelievakkRknivPileDArkPekYralvekvDvifaDvaqpdqarilaknaklflkeggyllis 174
sHvsDivg++gvvy++e s+r +r+li +akkR+n++Pi+eDAr+P+kYr+l+ +vDv+faDvaqp+qa+i+a+n+ +flk++g+++is
sp|Q55CW0|FBRL_DICDI 187 SHVSDIVGPTGVVYGIELSHRPGRDLIGMAKKRTNVIPIIEDARHPQKYRMLIGMVDVVFADVAQPNQAQIVAQNSAYFLKNEGHFIIS 275
***************************************************************************************** PP
EEHHHHHSSSSHHHHHHHHHHHHHHTTEEEEEEE.E-TTTSTTEEEEEEEEE CS
Fibrillarin 175 ikarsidvtkepeevfkeeveklkeeglkvleqv.klepyekdhalvvgkyk 225
ika++id+t+ +e v ++e++klk+e+l++++ + +l+pye++h lv+g+y+
sp|Q55CW0|FBRL_DICDI 276 IKASCIDSTAPTEVVVQNEITKLKKEKLRPQHLLkTLDPYERNHSLVIGVYR 327
********************************9857*************997 PP
>> tr|Q54LU3|Q54LU3_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0186961 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 20.7 0.2 4.9e-08 0.00012 52 206 .. 59 214 .. 7 221 .. 0.76
Alignments for each domain:
== domain 1 score: 20.7 bits; conditional E-value: 4.9e-08
TSHHHHHHHTT-S--S--TTSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSHHHHHHHHHHHTTSTTEEEEES-TTS.G...GGG CS
Fibrillarin 52 rsKlaaailkglkelpikkgskvLYlGaasGttvsHvsDivgeegvvyavefsprvlrelievakkRknivPileDArk.P...ekY 134
+ ++ a ++l++++g+kv+ G ++G+ + +v+ +g+v +++ s ++ + +++ +n+ ++DA++ P + +
tr|Q54LU3|Q54LU3_DICDI 59 QDQIIAHTRYSTRQLYLQPGQKVMDCGCGAGKDLGRLESMVEGNGIVVGMDISREMVECAKSRMSHLPNVKIFIGDASRiPiddNYF 145
444555555677899***********************************998655555555555567888899**96436332345 PP
TTTS--EEEEEEESSSTTHHHHHHHHHHHHEEEEEEEEEEEEHHHHHSSSSHHHHHHHHHHHHHHTTEEEEE CS
Fibrillarin 135 ralvekvDvifaDvaqpdqarilaknaklflkeggyllisikarsidvtkepeevfkeeveklkeeglkvle 206
a v + + + v +pd ++++ ++ +k+gg ++i+ s ++ p+++ + +++ l++ ++ +
tr|Q54LU3|Q54LU3_DICDI 146 DAYVIRCERLLQHVINPD---LVISEMTRVIKSGGRIVITDADWSSTSVSIPKNIEEINKKILNDVVFNAHP 214
788999999999999997...689999999*********999999999999999999999998887777655 PP
>> tr|Q55GM3|Q55GM3_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0189402 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 14.4 0.0 4.1e-06 0.011 73 150 .. 3 75 .. 2 106 .. 0.85
Alignments for each domain:
== domain 1 score: 14.4 bits; conditional E-value: 4.1e-06
EEEEESTTTSHHHHHHH.HHHTTTSEEEEEESSHHHHHHHHHHHTTSTTEEEEES-TTSGGGGTTTS--EEEEEEESSS CS
Fibrillarin 73 kvLYlGaasGttvsHvs.DivgeegvvyavefsprvlrelievakkRknivPileDArkPekYralvekvDvifaDvaq 150
k+L lG +sG s +s +v + +vy++ + + +l++ + i+Pi++DA++ ek+ + kvD+i +a+
tr|Q55GM3|Q55GM3_DICDI 3 KILILG-SSGFIGSEISlGLVRNGYKVYGLTRKEESANQLLK-----NEIIPIIADAKQVEKWLPIALKVDIIIDTIAD 75
678887.57888889984577766689999999999999985.....78************************988875 PP
>> tr|Q54KV1|Q54KV1_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0187275 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 14.5 0.1 4.1e-06 0.01 73 152 .. 3 77 .. 1 109 [. 0.84
Alignments for each domain:
== domain 1 score: 14.5 bits; conditional E-value: 4.1e-06
EEEEESTTTSHHHHHHHHHHTTTS.EEEEEESSHHHHHHHHHHHTTSTTEEEEES-TTSGGGGTTTS--EEEEEEESSSTT CS
Fibrillarin 73 kvLYlGaasGttvsHvsDivgeeg.vvyavefsprvlrelievakkRknivPileDArkPekYralvekvDvifaDvaqpd 152
+vL lG +sG s +s ++ ++g +vy++ + + +li R+ i+Pi++D r+ ek+ + kvD+i + +a+ +
tr|Q54KV1|Q54KV1_DICDI 3 NVLILG-SSGFIGSELSLVLVRNGfKVYGLTRRQESADQLI-----RNEIIPIVADVREIEKWLPIALKVDIIVEAIADLT 77
688888.5799999999888888846999999999999997.....99*************************99999754 PP
>> tr|Q54F82|Q54F82_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0189214 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 13.6 0.1 7.3e-06 0.019 114 209 .. 38 137 .. 29 151 .. 0.73
Alignments for each domain:
== domain 1 score: 13.6 bits; conditional E-value: 7.3e-06
HHTTSTTEEEEES-TTSGGGGTTTS-.-EEEEEEESSSTT.HHHHHHHHHHHHEEE.EEEEEEEEEHHHHHSSSSHHHHHH.HHHHH CS
Fibrillarin 114 vakkRknivPileDArkPekYralve.kvDvifaDvaqpd.qarilaknaklflke.ggyllisikarsidvtkepeevfk.eevek 196
+ kR+ i+Pi+ D + +k+ +lve ++D++ + ++ + ++ l++n + lke +g l +i +++ + ++e+ + ++
tr|Q54F82|Q54F82_DICDI 38 LKMKRNEIIPIICDVSDESKWFNLVEtEIDIVIESISSRNpETPKLVLNYLVKLKEiKGDNLTIIFTNASFSFGDNENLIDeKSNSR 124
5679*********************989********864425666778888888865676666666666666666665554045567 PP
HHHTTEEEEEEEE CS
Fibrillarin 197 lkeeglkvleqvk 209
l+++g k +++++
tr|Q54F82|Q54F82_DICDI 125 LNTDGWKAIKEIE 137
8888888877765 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (226 nodes)
Target sequences: 12739 (6856946 residues searched)
Passed MSV filter: 505 (0.039642); expected 254.8 (0.02)
Passed bias filter: 190 (0.0149148); expected 254.8 (0.02)
Passed Vit filter: 15 (0.00117749); expected 12.7 (0.001)
Passed Fwd filter: 5 (0.000392495); expected 0.1 (1e-05)
Initial search space (Z): 12739 [actual number of targets]
Domain search space (domZ): 5 [number of targets reported over threshold]
# CPU time: 0.11u 0.01s 00:00:00.12 Elapsed: 00:00:00.06
# Mc/sec: 25827.83
//
[ok]