# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Fibrillarin.hmm.txt
# target sequence database: proteomes/Drosophila_melanogaster.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Fibrillarin [M=226]
Accession: PF01269.17
Description: Fibrillarin
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
1.1e-108 361.3 0.0 1.3e-108 361.0 0.0 1.0 1 sp|Q9W1V3|FBRL_DROME rRNA 2'-O-methyltransferase fibrillar
9.5e-78 260.0 0.0 1.2e-77 259.7 0.0 1.1 1 tr|Q9VG21|Q9VG21_DROME IP10714p OS=Drosophila melanogaster O
2.7e-06 26.3 0.0 4.5e-06 25.6 0.0 1.3 1 tr|Q9VDZ4|Q9VDZ4_DROME LD16340p OS=Drosophila melanogaster O
0.0012 17.7 0.0 0.0019 17.0 0.0 1.2 1 tr|Q8IPS4|Q8IPS4_DROME FI01826p OS=Drosophila melanogaster O
------ inclusion threshold ------
0.06 12.1 0.0 0.11 11.2 0.0 1.4 1 tr|A1Z909|A1Z909_DROME LD11307p OS=Drosophila melanogaster O
Domain annotation for each sequence (and alignments):
>> sp|Q9W1V3|FBRL_DROME rRNA 2'-O-methyltransferase fibrillarin OS=Drosophila melanogaster OX=7227 GN=Fib PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 361.0 0.0 4.6e-112 1.3e-108 1 225 [. 113 339 .. 113 340 .. 0.99
Alignments for each domain:
== domain 1 score: 361.0 bits; conditional E-value: 4.6e-112
EEEECSSTTEEEEETTSSEEEEEE-SSTT--SSSSEEEEETTE....EEEEE-TTTSHHHHHHHTT-S--S--TTSEEEEESTTTSHHH CS
Fibrillarin 1 veeheklegvyivkekgdarlatknlvpgekvYgEklikveee....EyRvWnpfrsKlaaailkglkelpikkgskvLYlGaasGttv 85
+e+h ++egv+i+++k+da l+t+n+vpg++vYgEk+i+ve++ EyRvWnpfrsKlaaa+l g++++++ +gskvLYlGaasGttv
sp|Q9W1V3|FBRL_DROME 113 IEPH-RHEGVFIARGKEDA-LVTRNFVPGSEVYGEKRISVETNgekiEYRVWNPFRSKLAAAVLGGVEQIHMPPGSKVLYLGAASGTTV 199
5788.9**********999.*********************9999******************************************** PP
HHHHHHHTTTSEEEEEESSHHHHHHHHHHHTTSTTEEEEES-TTSGGGGTTTS--EEEEEEESSSTTHHHHHHHHHHHHEEEEEEEEEE CS
Fibrillarin 86 sHvsDivgeegvvyavefsprvlrelievakkRknivPileDArkPekYralvekvDvifaDvaqpdqarilaknaklflkeggyllis 174
sHvsD+vg+eg+vyavefs+r++r+li+vakkR+ni+Pi+eDAr+P+kYr+lv +vD+ifaDvaqpdq ri+a+na++flk+gg+++is
sp|Q9W1V3|FBRL_DROME 200 SHVSDVVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPIIEDARHPHKYRMLVGMVDTIFADVAQPDQGRIVALNAQHFLKNGGHFVIS 288
***************************************************************************************** PP
EEHHHHHSSSSHHHHHHHHHHHHHHTTEEEEEEEE-TTTSTTEEEEEEEEE CS
Fibrillarin 175 ikarsidvtkepeevfkeeveklkeeglkvleqvklepyekdhalvvgkyk 225
ika++id+t++pe+vf++ev+k++ ++lk++eq++lepye+dha+vvg+y+
sp|Q9W1V3|FBRL_DROME 289 IKASCIDSTAQPEAVFAAEVKKMQADKLKPQEQLTLEPYERDHAVVVGVYR 339
************************************************997 PP
>> tr|Q9VG21|Q9VG21_DROME IP10714p OS=Drosophila melanogaster OX=7227 GN=Dmel\CG10909 PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 259.7 0.0 4.3e-81 1.2e-77 1 224 [. 114 342 .. 114 344 .. 0.98
Alignments for each domain:
== domain 1 score: 259.7 bits; conditional E-value: 4.3e-81
EEEECSSTTEEEEETTSSE.EEEEE-SSTT--SSSSEEEEETTE....EEEEE-TTTSHHHHHHHTT-S--S--TTSEEEEESTTTS CS
Fibrillarin 1 veeheklegvyivkekgda.rlatknlvpgekvYgEklikveee....EyRvWnpfrsKlaaailkglkelpikkgskvLYlGaasG 82
+e+h +++gvy+++++ da +l+t+n++++++ YgE+++ +e + E+RvW+pf+sKlaa+i+ g+++l+++ gskvLYlGa+ G
tr|Q9VG21|Q9VG21_DROME 114 IEPH-RHYGVYLLRNRFDAiQLLTRNTSSSADDYGERRVISEYRemrcEFRVWSPFQSKLAAGIMGGVSDLHLQIGSKVLYLGAGFG 199
5788.9********9999889*******************9999999**************************************** PP
HHHHHHHHHHTTTSEEEEEESSHHHHHHHHHHHTTSTTEEEEES-TTSGGGGTTTS-.-EEEEEEESSSTTHHHHHHHHHHHHEEEE CS
Fibrillarin 83 ttvsHvsDivgeegvvyavefsprvlrelievakkRknivPileDArkPekYralve.kvDvifaDvaqpdqarilaknaklflkeg 168
++vsH+sDivg++g+vyave+ p+++r+l+ +a++R+nivPi+eDA++P+kYr+ v+ ++D+ifaD+ + +r l++na++fl+ g
tr|Q9VG21|Q9VG21_DROME 200 RSVSHISDIVGDSGMVYAVEQIPWAGRQLTIMANRRSNIVPIVEDATMPYKYRYEVPaCIDIIFADLPPSVLIRALMLNARHFLNPG 286
********************************************************989**************************** PP
EEEEEEEEHHHHHSSSSHHHHHHHHHHHHHHTTEEEEEEEE-TTTSTTEEEEEEEE CS
Fibrillarin 169 gyllisikarsidvtkepeevfkeeveklkeeglkvleqvklepyekdhalvvgky 224
g+++ ++++ + + ++ +++ f++e++ lke++l+++e+v lep++ +a+vvg+y
tr|Q9VG21|Q9VG21_DROME 287 GHFVAYLHSPTSQGVVFNKDSFAAERRLLKEKQLEPKEMVLLEPFKAGYAFVVGVY 342
******************************************************98 PP
>> tr|Q9VDZ4|Q9VDZ4_DROME LD16340p OS=Drosophila melanogaster OX=7227 GN=Nsun5 PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 25.6 0.0 1.6e-09 4.5e-06 70 129 .. 227 288 .. 216 304 .. 0.87
Alignments for each domain:
== domain 1 score: 25.6 bits; conditional E-value: 1.6e-09
TTSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSHHHHHHHHHHHTTS..TTEEEEES-TT CS
Fibrillarin 70 kgskvLYlGaasGttvsHvsDivgeegvvyavefsprvlrelievakkR..knivPileDAr 129
+g+ vL + aa G H+ ++++++g++y+ve+ + l+e++k+ + Pil+DA
tr|Q9VDZ4|Q9VDZ4_DROME 227 SGATVLDMCAAPGMKTVHICNVMQNKGCIYSVEQDHVRYNTLCEITKDAgcDIVKPILGDAL 288
6899*****************************************9975224577*****95 PP
>> tr|Q8IPS4|Q8IPS4_DROME FI01826p OS=Drosophila melanogaster OX=7227 GN=Dmel\CG11109 PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 17.0 0.0 6.9e-07 0.0019 69 112 .. 226 269 .. 217 280 .. 0.89
Alignments for each domain:
== domain 1 score: 17.0 bits; conditional E-value: 6.9e-07
-TTSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSHHHHHHHH CS
Fibrillarin 69 kkgskvLYlGaasGttvsHvsDivgeegvvyavefsprvlreli 112
++g+++L + aa G sH+++++g++g v a++ s +r ++
tr|Q8IPS4|Q8IPS4_DROME 226 QPGERILDMCAAPGNKTSHIAELMGDRGSVVALDNSASRVRSML 269
799*********************************99999876 PP
>> tr|A1Z909|A1Z909_DROME LD11307p OS=Drosophila melanogaster OX=7227 GN=CG8545-RA PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.2 0.0 4.1e-05 0.11 68 147 .. 433 511 .. 421 521 .. 0.83
Alignments for each domain:
== domain 1 score: 11.2 bits; conditional E-value: 4.1e-05
--TTSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSHHHHHHHHHHHTTSTTEEEEES-TTSGGGGTTTS--EEEEEEE CS
Fibrillarin 68 ikkgskvLYlGaasGttvsHvsDivgeegvvyavefsprvlrelievakkRknivPileDArkPekYralvekvDvifaD 147
++++++L + +a G sH++ i++++gv++a + ++ ++ +R iv + + +k+r++++ D + D
tr|A1Z909|A1Z909_DROME 433 PQENERILDMCSAPGGKGSHIASIMKNTGVLFANDSNRDRIKAIV-ANFHRLGIVNAVVSCEDGTKFRNIMTGFDRVLLD 511
578999***************************887776676665.4568999999999999999999999998888777 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (226 nodes)
Target sequences: 13786 (7394964 residues searched)
Passed MSV filter: 321 (0.0232845); expected 275.7 (0.02)
Passed bias filter: 251 (0.0182069); expected 275.7 (0.02)
Passed Vit filter: 18 (0.00130567); expected 13.8 (0.001)
Passed Fwd filter: 5 (0.000362687); expected 0.1 (1e-05)
Initial search space (Z): 13786 [actual number of targets]
Domain search space (domZ): 5 [number of targets reported over threshold]
# CPU time: 0.15u 0.01s 00:00:00.16 Elapsed: 00:00:00.06
# Mc/sec: 27854.36
//
[ok]