# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Fibrillarin.hmm.txt # target sequence database: proteomes/Drosophila_melanogaster.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Fibrillarin [M=226] Accession: PF01269.17 Description: Fibrillarin Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-108 361.3 0.0 1.3e-108 361.0 0.0 1.0 1 sp|Q9W1V3|FBRL_DROME rRNA 2'-O-methyltransferase fibrillar 9.5e-78 260.0 0.0 1.2e-77 259.7 0.0 1.1 1 tr|Q9VG21|Q9VG21_DROME IP10714p OS=Drosophila melanogaster O 2.7e-06 26.3 0.0 4.5e-06 25.6 0.0 1.3 1 tr|Q9VDZ4|Q9VDZ4_DROME LD16340p OS=Drosophila melanogaster O 0.0012 17.7 0.0 0.0019 17.0 0.0 1.2 1 tr|Q8IPS4|Q8IPS4_DROME FI01826p OS=Drosophila melanogaster O ------ inclusion threshold ------ 0.06 12.1 0.0 0.11 11.2 0.0 1.4 1 tr|A1Z909|A1Z909_DROME LD11307p OS=Drosophila melanogaster O Domain annotation for each sequence (and alignments): >> sp|Q9W1V3|FBRL_DROME rRNA 2'-O-methyltransferase fibrillarin OS=Drosophila melanogaster OX=7227 GN=Fib PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 361.0 0.0 4.6e-112 1.3e-108 1 225 [. 113 339 .. 113 340 .. 0.99 Alignments for each domain: == domain 1 score: 361.0 bits; conditional E-value: 4.6e-112 EEEECSSTTEEEEETTSSEEEEEE-SSTT--SSSSEEEEETTE....EEEEE-TTTSHHHHHHHTT-S--S--TTSEEEEESTTTSHHH CS Fibrillarin 1 veeheklegvyivkekgdarlatknlvpgekvYgEklikveee....EyRvWnpfrsKlaaailkglkelpikkgskvLYlGaasGttv 85 +e+h ++egv+i+++k+da l+t+n+vpg++vYgEk+i+ve++ EyRvWnpfrsKlaaa+l g++++++ +gskvLYlGaasGttv sp|Q9W1V3|FBRL_DROME 113 IEPH-RHEGVFIARGKEDA-LVTRNFVPGSEVYGEKRISVETNgekiEYRVWNPFRSKLAAAVLGGVEQIHMPPGSKVLYLGAASGTTV 199 5788.9**********999.*********************9999******************************************** PP HHHHHHHTTTSEEEEEESSHHHHHHHHHHHTTSTTEEEEES-TTSGGGGTTTS--EEEEEEESSSTTHHHHHHHHHHHHEEEEEEEEEE CS Fibrillarin 86 sHvsDivgeegvvyavefsprvlrelievakkRknivPileDArkPekYralvekvDvifaDvaqpdqarilaknaklflkeggyllis 174 sHvsD+vg+eg+vyavefs+r++r+li+vakkR+ni+Pi+eDAr+P+kYr+lv +vD+ifaDvaqpdq ri+a+na++flk+gg+++is sp|Q9W1V3|FBRL_DROME 200 SHVSDVVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPIIEDARHPHKYRMLVGMVDTIFADVAQPDQGRIVALNAQHFLKNGGHFVIS 288 ***************************************************************************************** PP EEHHHHHSSSSHHHHHHHHHHHHHHTTEEEEEEEE-TTTSTTEEEEEEEEE CS Fibrillarin 175 ikarsidvtkepeevfkeeveklkeeglkvleqvklepyekdhalvvgkyk 225 ika++id+t++pe+vf++ev+k++ ++lk++eq++lepye+dha+vvg+y+ sp|Q9W1V3|FBRL_DROME 289 IKASCIDSTAQPEAVFAAEVKKMQADKLKPQEQLTLEPYERDHAVVVGVYR 339 ************************************************997 PP >> tr|Q9VG21|Q9VG21_DROME IP10714p OS=Drosophila melanogaster OX=7227 GN=Dmel\CG10909 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 259.7 0.0 4.3e-81 1.2e-77 1 224 [. 114 342 .. 114 344 .. 0.98 Alignments for each domain: == domain 1 score: 259.7 bits; conditional E-value: 4.3e-81 EEEECSSTTEEEEETTSSE.EEEEE-SSTT--SSSSEEEEETTE....EEEEE-TTTSHHHHHHHTT-S--S--TTSEEEEESTTTS CS Fibrillarin 1 veeheklegvyivkekgda.rlatknlvpgekvYgEklikveee....EyRvWnpfrsKlaaailkglkelpikkgskvLYlGaasG 82 +e+h +++gvy+++++ da +l+t+n++++++ YgE+++ +e + E+RvW+pf+sKlaa+i+ g+++l+++ gskvLYlGa+ G tr|Q9VG21|Q9VG21_DROME 114 IEPH-RHYGVYLLRNRFDAiQLLTRNTSSSADDYGERRVISEYRemrcEFRVWSPFQSKLAAGIMGGVSDLHLQIGSKVLYLGAGFG 199 5788.9********9999889*******************9999999**************************************** PP HHHHHHHHHHTTTSEEEEEESSHHHHHHHHHHHTTSTTEEEEES-TTSGGGGTTTS-.-EEEEEEESSSTTHHHHHHHHHHHHEEEE CS Fibrillarin 83 ttvsHvsDivgeegvvyavefsprvlrelievakkRknivPileDArkPekYralve.kvDvifaDvaqpdqarilaknaklflkeg 168 ++vsH+sDivg++g+vyave+ p+++r+l+ +a++R+nivPi+eDA++P+kYr+ v+ ++D+ifaD+ + +r l++na++fl+ g tr|Q9VG21|Q9VG21_DROME 200 RSVSHISDIVGDSGMVYAVEQIPWAGRQLTIMANRRSNIVPIVEDATMPYKYRYEVPaCIDIIFADLPPSVLIRALMLNARHFLNPG 286 ********************************************************989**************************** PP EEEEEEEEHHHHHSSSSHHHHHHHHHHHHHHTTEEEEEEEE-TTTSTTEEEEEEEE CS Fibrillarin 169 gyllisikarsidvtkepeevfkeeveklkeeglkvleqvklepyekdhalvvgky 224 g+++ ++++ + + ++ +++ f++e++ lke++l+++e+v lep++ +a+vvg+y tr|Q9VG21|Q9VG21_DROME 287 GHFVAYLHSPTSQGVVFNKDSFAAERRLLKEKQLEPKEMVLLEPFKAGYAFVVGVY 342 ******************************************************98 PP >> tr|Q9VDZ4|Q9VDZ4_DROME LD16340p OS=Drosophila melanogaster OX=7227 GN=Nsun5 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.6 0.0 1.6e-09 4.5e-06 70 129 .. 227 288 .. 216 304 .. 0.87 Alignments for each domain: == domain 1 score: 25.6 bits; conditional E-value: 1.6e-09 TTSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSHHHHHHHHHHHTTS..TTEEEEES-TT CS Fibrillarin 70 kgskvLYlGaasGttvsHvsDivgeegvvyavefsprvlrelievakkR..knivPileDAr 129 +g+ vL + aa G H+ ++++++g++y+ve+ + l+e++k+ + Pil+DA tr|Q9VDZ4|Q9VDZ4_DROME 227 SGATVLDMCAAPGMKTVHICNVMQNKGCIYSVEQDHVRYNTLCEITKDAgcDIVKPILGDAL 288 6899*****************************************9975224577*****95 PP >> tr|Q8IPS4|Q8IPS4_DROME FI01826p OS=Drosophila melanogaster OX=7227 GN=Dmel\CG11109 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.0 0.0 6.9e-07 0.0019 69 112 .. 226 269 .. 217 280 .. 0.89 Alignments for each domain: == domain 1 score: 17.0 bits; conditional E-value: 6.9e-07 -TTSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSHHHHHHHH CS Fibrillarin 69 kkgskvLYlGaasGttvsHvsDivgeegvvyavefsprvlreli 112 ++g+++L + aa G sH+++++g++g v a++ s +r ++ tr|Q8IPS4|Q8IPS4_DROME 226 QPGERILDMCAAPGNKTSHIAELMGDRGSVVALDNSASRVRSML 269 799*********************************99999876 PP >> tr|A1Z909|A1Z909_DROME LD11307p OS=Drosophila melanogaster OX=7227 GN=CG8545-RA PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.2 0.0 4.1e-05 0.11 68 147 .. 433 511 .. 421 521 .. 0.83 Alignments for each domain: == domain 1 score: 11.2 bits; conditional E-value: 4.1e-05 --TTSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSHHHHHHHHHHHTTSTTEEEEES-TTSGGGGTTTS--EEEEEEE CS Fibrillarin 68 ikkgskvLYlGaasGttvsHvsDivgeegvvyavefsprvlrelievakkRknivPileDArkPekYralvekvDvifaD 147 ++++++L + +a G sH++ i++++gv++a + ++ ++ +R iv + + +k+r++++ D + D tr|A1Z909|A1Z909_DROME 433 PQENERILDMCSAPGGKGSHIASIMKNTGVLFANDSNRDRIKAIV-ANFHRLGIVNAVVSCEDGTKFRNIMTGFDRVLLD 511 578999***************************887776676665.4568999999999999999999999998888777 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (226 nodes) Target sequences: 13786 (7394964 residues searched) Passed MSV filter: 321 (0.0232845); expected 275.7 (0.02) Passed bias filter: 251 (0.0182069); expected 275.7 (0.02) Passed Vit filter: 18 (0.00130567); expected 13.8 (0.001) Passed Fwd filter: 5 (0.000362687); expected 0.1 (1e-05) Initial search space (Z): 13786 [actual number of targets] Domain search space (domZ): 5 [number of targets reported over threshold] # CPU time: 0.15u 0.01s 00:00:00.16 Elapsed: 00:00:00.06 # Mc/sec: 27854.36 // [ok]