# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/Fibrillarin.hmm.txt
# target sequence database:        proteomes/Homo_sapiens.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       Fibrillarin  [M=226]
Accession:   PF01269.17
Description: Fibrillarin
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
   1.3e-108  363.6   0.1   1.6e-108  363.4   0.1    1.0  1  tr|M0R299|M0R299_HUMAN  rRNA 2'-O-methyltransferase fibrillar
     3e-108  362.4   0.0   3.6e-108  362.2   0.0    1.0  1  sp|P22087|FBRL_HUMAN    rRNA 2'-O-methyltransferase fibrillar
     7e-106  354.7   0.0   8.3e-106  354.5   0.0    1.0  1  sp|A6NHQ2|FBLL1_HUMAN   rRNA/tRNA 2'-O-methyltransferase fibr
   7.1e-106  354.7   0.0   8.3e-106  354.4   0.0    1.0  1  tr|R4GMW7|R4GMW7_HUMAN  rRNA/tRNA 2'-O-methyltransferase fibr
   4.3e-105  352.1   0.0   5.1e-105  351.9   0.0    1.0  1  tr|M0QXL5|M0QXL5_HUMAN  rRNA 2'-O-methyltransferase fibrillar
    3.3e-99  332.9   0.0      4e-99  332.6   0.0    1.0  1  tr|M0R2Q4|M0R2Q4_HUMAN  rRNA 2'-O-methyltransferase fibrillar
    1.2e-86  291.7   0.0    1.5e-86  291.5   0.0    1.0  1  tr|M0R0P1|M0R0P1_HUMAN  rRNA 2'-O-methyltransferase fibrillar
    3.3e-45  156.2   0.0    3.9e-45  156.0   0.0    1.0  1  tr|M0R1H0|M0R1H0_HUMAN  rRNA 2'-O-methyltransferase fibrillar
    2.3e-40  140.4   0.0    2.8e-40  140.1   0.0    1.0  1  tr|M0R2B0|M0R2B0_HUMAN  rRNA 2'-O-methyltransferase fibrillar
    1.5e-30  108.3   0.0    1.8e-30  108.0   0.0    1.0  1  tr|M0R2U2|M0R2U2_HUMAN  rRNA 2'-O-methyltransferase fibrillar
  ------ inclusion threshold ------
       0.64   11.4   0.0       0.77   11.1   0.0    1.1  1  tr|Q5VZD9|Q5VZD9_HUMAN  Mitochondrial ornithine transporter 1


Domain annotation for each sequence (and alignments):
>> tr|M0R299|M0R299_HUMAN  rRNA 2'-O-methyltransferase fibrillarin (Fragment) OS=Homo sapiens GN=FBL PE=2 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  363.4   0.1    2e-112  1.6e-108       1     225 [.       3     229 .]       3     229 .] 0.98

  Alignments for each domain:
  == domain 1  score: 363.4 bits;  conditional E-value: 2e-112
                             EEEECSSTTEEEEETTSSEEEEEE-SSTT--SSSSEEEEETTE....EEEEE-TTTSHHHHHHHTT-S--S--TTSEEEEESTTTSH CS
             Fibrillarin   1 veeheklegvyivkekgdarlatknlvpgekvYgEklikveee....EyRvWnpfrsKlaaailkglkelpikkgskvLYlGaasGt 83 
                             ve+h ++egv+i+++k+da l+tknlvpge+vYgEk++++ e     EyR WnpfrsKlaaail g+++++ik+g+kvLYlGaasGt
  tr|M0R299|M0R299_HUMAN   3 VEPH-RHEGVFICRGKEDA-LVTKNLVPGESVYGEKRVSISEGddkiEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGT 87 
                             6788.***********999.*******************98877899**************************************** PP

                             HHHHHHHHHTTTSEEEEEESSHHHHHHHHHHHTTSTTEEEEES-TTSGGGGTTTS--EEEEEEESSSTTHHHHHHHHHHHHEEEEEE CS
             Fibrillarin  84 tvsHvsDivgeegvvyavefsprvlrelievakkRknivPileDArkPekYralvekvDvifaDvaqpdqarilaknaklflkeggy 170
                             tvsHvsDivg++g+vyavefs+r++r+li++akkR+ni+P++eDAr+P+kYr+l+ +vDvifaDvaqpdq+ri+a+na++fl++gg+
  tr|M0R299|M0R299_HUMAN  88 TVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGH 174
                             *************************************************************************************** PP

                             EEEEEEHHHHHSSSSHHHHHHHHHHHHHHTTEEEEEEEE-TTTSTTEEEEEEEEE CS
             Fibrillarin 171 llisikarsidvtkepeevfkeeveklkeeglkvleqvklepyekdhalvvgkyk 225
                             ++isika++id+t+++e+vf++ev+k+++e++k++eq++lepye+dha+vvg+y+
  tr|M0R299|M0R299_HUMAN 175 FVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYR 229
                             ****************************************************985 PP

>> sp|P22087|FBRL_HUMAN  rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens GN=FBL PE=1 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  362.2   0.0  4.5e-112  3.6e-108       1     225 [.      88     314 ..      88     315 .. 0.98

  Alignments for each domain:
  == domain 1  score: 362.2 bits;  conditional E-value: 4.5e-112
                           EEEECSSTTEEEEETTSSEEEEEE-SSTT--SSSSEEEEETTE....EEEEE-TTTSHHHHHHHTT-S--S--TTSEEEEESTTTSHHH CS
           Fibrillarin   1 veeheklegvyivkekgdarlatknlvpgekvYgEklikveee....EyRvWnpfrsKlaaailkglkelpikkgskvLYlGaasGttv 85 
                           ve+h ++egv+i+++k+da l+tknlvpge+vYgEk++++ e     EyR WnpfrsKlaaail g+++++ik+g+kvLYlGaasGttv
  sp|P22087|FBRL_HUMAN  88 VEPH-RHEGVFICRGKEDA-LVTKNLVPGESVYGEKRVSISEGddkiEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTV 174
                           6788.***********999.*******************98877899****************************************** PP

                           HHHHHHHTTTSEEEEEESSHHHHHHHHHHHTTSTTEEEEES-TTSGGGGTTTS--EEEEEEESSSTTHHHHHHHHHHHHEEEEEEEEEE CS
           Fibrillarin  86 sHvsDivgeegvvyavefsprvlrelievakkRknivPileDArkPekYralvekvDvifaDvaqpdqarilaknaklflkeggyllis 174
                           sHvsDivg++g+vyavefs+r++r+li++akkR+ni+P++eDAr+P+kYr+l+ +vDvifaDvaqpdq+ri+a+na++fl++gg+++is
  sp|P22087|FBRL_HUMAN 175 SHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVIS 263
                           ***************************************************************************************** PP

                           EEHHHHHSSSSHHHHHHHHHHHHHHTTEEEEEEEE-TTTSTTEEEEEEEEE CS
           Fibrillarin 175 ikarsidvtkepeevfkeeveklkeeglkvleqvklepyekdhalvvgkyk 225
                           ika++id+t+++e+vf++ev+k+++e++k++eq++lepye+dha+vvg+y+
  sp|P22087|FBRL_HUMAN 264 IKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYR 314
                           ************************************************997 PP

>> sp|A6NHQ2|FBLL1_HUMAN  rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1 OS=Homo sapiens GN=FBLL1 PE=1 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  354.5   0.0    1e-109  8.3e-106       1     225 [.     100     326 ..     100     327 .. 0.98

  Alignments for each domain:
  == domain 1  score: 354.5 bits;  conditional E-value: 1e-109
                            EEEECSSTTEEEEETTSSEEEEEE-SSTT--SSSSEEEEETTE....EEEEE-TTTSHHHHHHHTT-S--S--TTSEEEEESTTTSHH CS
            Fibrillarin   1 veeheklegvyivkekgdarlatknlvpgekvYgEklikveee....EyRvWnpfrsKlaaailkglkelpikkgskvLYlGaasGtt 84 
                            ve+h ++egv+i ++ +da l+t n+vpg++vYgE++++v+e     EyR+WnpfrsKlaaail g+++++ik+ skvLYlGaasGtt
  sp|A6NHQ2|FBLL1_HUMAN 100 VEPH-RHEGVFIYRGAEDA-LVTLNMVPGQSVYGERRVTVTEGgvkqEYRTWNPFRSKLAAAILGGVDQIHIKPKSKVLYLGAASGTT 185
                            6788.**********9999.********************9888889***************************************** PP

                            HHHHHHHHTTTSEEEEEESSHHHHHHHHHHHTTSTTEEEEES-TTSGGGGTTTS--EEEEEEESSSTTHHHHHHHHHHHHEEEEEEEE CS
            Fibrillarin  85 vsHvsDivgeegvvyavefsprvlrelievakkRknivPileDArkPekYralvekvDvifaDvaqpdqarilaknaklflkeggyll 172
                            vsHvsDi+g++g+vyavefs+r++r+l++vakkR+ni+P+leDAr+P kYr+l+ +vDvifaDvaqpdq ri+a+na++fl++gg++l
  sp|A6NHQ2|FBLL1_HUMAN 186 VSHVSDIIGPDGLVYAVEFSHRAGRDLVNVAKKRTNIIPVLEDARHPLKYRMLIGMVDVIFADVAQPDQSRIVALNAHTFLRNGGHFL 273
                            **************************************************************************************** PP

                            EEEEHHHHHSSSSHHHHHHHHHHHHHHTTEEEEEEEE-TTTSTTEEEEEEEEE CS
            Fibrillarin 173 isikarsidvtkepeevfkeeveklkeeglkvleqvklepyekdhalvvgkyk 225
                            isika++id+t+++e+vf++ev+kl++e+lk++eq++lepye+dha+vvg+y+
  sp|A6NHQ2|FBLL1_HUMAN 274 ISIKANCIDSTASAEAVFASEVRKLQQENLKPQEQLTLEPYERDHAVVVGVYR 326
                            **************************************************997 PP

>> tr|R4GMW7|R4GMW7_HUMAN  rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1 OS=Homo sapiens GN=FBLL1 PE=3 SV=
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  354.4   0.0    1e-109  8.3e-106       1     225 [.     100     326 ..     100     327 .. 0.98

  Alignments for each domain:
  == domain 1  score: 354.4 bits;  conditional E-value: 1e-109
                             EEEECSSTTEEEEETTSSEEEEEE-SSTT--SSSSEEEEETTE....EEEEE-TTTSHHHHHHHTT-S--S--TTSEEEEESTTTSH CS
             Fibrillarin   1 veeheklegvyivkekgdarlatknlvpgekvYgEklikveee....EyRvWnpfrsKlaaailkglkelpikkgskvLYlGaasGt 83 
                             ve+h ++egv+i ++ +da l+t n+vpg++vYgE++++v+e     EyR+WnpfrsKlaaail g+++++ik+ skvLYlGaasGt
  tr|R4GMW7|R4GMW7_HUMAN 100 VEPH-RHEGVFIYRGAEDA-LVTLNMVPGQSVYGERRVTVTEGgvkqEYRTWNPFRSKLAAAILGGVDQIHIKPKSKVLYLGAASGT 184
                             6788.**********9999.********************9888889**************************************** PP

                             HHHHHHHHHTTTSEEEEEESSHHHHHHHHHHHTTSTTEEEEES-TTSGGGGTTTS--EEEEEEESSSTTHHHHHHHHHHHHEEEEEE CS
             Fibrillarin  84 tvsHvsDivgeegvvyavefsprvlrelievakkRknivPileDArkPekYralvekvDvifaDvaqpdqarilaknaklflkeggy 170
                             tvsHvsDi+g++g+vyavefs+r++r+l++vakkR+ni+P+leDAr+P kYr+l+ +vDvifaDvaqpdq ri+a+na++fl++gg+
  tr|R4GMW7|R4GMW7_HUMAN 185 TVSHVSDIIGPDGLVYAVEFSHRAGRDLVNVAKKRTNIIPVLEDARHPLKYRMLIGMVDVIFADVAQPDQSRIVALNAHTFLRNGGH 271
                             *************************************************************************************** PP

                             EEEEEEHHHHHSSSSHHHHHHHHHHHHHHTTEEEEEEEE-TTTSTTEEEEEEEEE CS
             Fibrillarin 171 llisikarsidvtkepeevfkeeveklkeeglkvleqvklepyekdhalvvgkyk 225
                             +lisika++id+t+++e+vf++ev+kl++e+lk++eq++lepye+dha+vvg+y+
  tr|R4GMW7|R4GMW7_HUMAN 272 FLISIKANCIDSTASAEAVFASEVRKLQQENLKPQEQLTLEPYERDHAVVVGVYR 326
                             ****************************************************997 PP

>> tr|M0QXL5|M0QXL5_HUMAN  rRNA 2'-O-methyltransferase fibrillarin (Fragment) OS=Homo sapiens GN=FBL PE=2 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  351.9   0.0  6.3e-109  5.1e-105       1     217 [.      26     244 .]      26     244 .] 0.99

  Alignments for each domain:
  == domain 1  score: 351.9 bits;  conditional E-value: 6.3e-109
                             EEEECSSTTEEEEETTSSEEEEEE-SSTT--SSSSEEEEETTE....EEEEE-TTTSHHHHHHHTT-S--S--TTSEEEEESTTTSH CS
             Fibrillarin   1 veeheklegvyivkekgdarlatknlvpgekvYgEklikveee....EyRvWnpfrsKlaaailkglkelpikkgskvLYlGaasGt 83 
                             ve+h ++egv+i+++k+da l+tknlvpge+vYgEk++++ e     EyR WnpfrsKlaaail g+++++ik+g+kvLYlGaasGt
  tr|M0QXL5|M0QXL5_HUMAN  26 VEPH-RHEGVFICRGKEDA-LVTKNLVPGESVYGEKRVSISEGddkiEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGT 110
                             6788.***********999.*******************98877899**************************************** PP

                             HHHHHHHHHTTTSEEEEEESSHHHHHHHHHHHTTSTTEEEEES-TTSGGGGTTTS--EEEEEEESSSTTHHHHHHHHHHHHEEEEEE CS
             Fibrillarin  84 tvsHvsDivgeegvvyavefsprvlrelievakkRknivPileDArkPekYralvekvDvifaDvaqpdqarilaknaklflkeggy 170
                             tvsHvsDivg++g+vyavefs+r++r+li++akkR+ni+P++eDAr+P+kYr+l+ +vDvifaDvaqpdq+ri+a+na++fl++gg+
  tr|M0QXL5|M0QXL5_HUMAN 111 TVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGH 197
                             *************************************************************************************** PP

                             EEEEEEHHHHHSSSSHHHHHHHHHHHHHHTTEEEEEEEE-TTTSTTE CS
             Fibrillarin 171 llisikarsidvtkepeevfkeeveklkeeglkvleqvklepyekdh 217
                             ++isika++id+t+++e+vf++ev+k+++e++k++eq++lepye+dh
  tr|M0QXL5|M0QXL5_HUMAN 198 FVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDH 244
                             **********************************************9 PP

>> tr|M0R2Q4|M0R2Q4_HUMAN  rRNA 2'-O-methyltransferase fibrillarin (Fragment) OS=Homo sapiens GN=FBL PE=2 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  332.6   0.0  4.9e-103     4e-99       1     207 [.      64     272 ..      64     273 .] 0.98

  Alignments for each domain:
  == domain 1  score: 332.6 bits;  conditional E-value: 4.9e-103
                             EEEECSSTTEEEEETTSSEEEEEE-SSTT--SSSSEEEEETTE....EEEEE-TTTSHHHHHHHTT-S--S--TTSEEEEESTTTSH CS
             Fibrillarin   1 veeheklegvyivkekgdarlatknlvpgekvYgEklikveee....EyRvWnpfrsKlaaailkglkelpikkgskvLYlGaasGt 83 
                             ve+h ++egv+i+++k+da l+tknlvpge+vYgEk++++ e     EyR WnpfrsKlaaail g+++++ik+g+kvLYlGaasGt
  tr|M0R2Q4|M0R2Q4_HUMAN  64 VEPH-RHEGVFICRGKEDA-LVTKNLVPGESVYGEKRVSISEGddkiEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGT 148
                             6788.***********999.*******************98877899**************************************** PP

                             HHHHHHHHHTTTSEEEEEESSHHHHHHHHHHHTTSTTEEEEES-TTSGGGGTTTS--EEEEEEESSSTTHHHHHHHHHHHHEEEEEE CS
             Fibrillarin  84 tvsHvsDivgeegvvyavefsprvlrelievakkRknivPileDArkPekYralvekvDvifaDvaqpdqarilaknaklflkeggy 170
                             tvsHvsDivg++g+vyavefs+r++r+li++akkR+ni+P++eDAr+P+kYr+l+ +vDvifaDvaqpdq+ri+a+na++fl++gg+
  tr|M0R2Q4|M0R2Q4_HUMAN 149 TVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGH 235
                             *************************************************************************************** PP

                             EEEEEEHHHHHSSSSHHHHHHHHHHHHHHTTEEEEEE CS
             Fibrillarin 171 llisikarsidvtkepeevfkeeveklkeeglkvleq 207
                             ++isika++id+t+++e+vf++ev+k+++e++k++eq
  tr|M0R2Q4|M0R2Q4_HUMAN 236 FVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQ 272
                             **********************************998 PP

>> tr|M0R0P1|M0R0P1_HUMAN  rRNA 2'-O-methyltransferase fibrillarin (Fragment) OS=Homo sapiens GN=FBL PE=2 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  291.5   0.0   1.8e-90   1.5e-86       1     176 [.      51     228 .]      51     228 .] 0.98

  Alignments for each domain:
  == domain 1  score: 291.5 bits;  conditional E-value: 1.8e-90
                             EEEECSSTTEEEEETTSSEEEEEE-SSTT--SSSSEEEEETTE....EEEEE-TTTSHHHHHHHTT-S--S--TTSEEEEESTTTSH CS
             Fibrillarin   1 veeheklegvyivkekgdarlatknlvpgekvYgEklikveee....EyRvWnpfrsKlaaailkglkelpikkgskvLYlGaasGt 83 
                             ve+h ++egv+i+++k+da l+tknlvpge+vYgEk++++ e     EyR WnpfrsKlaaail g+++++ik+g+kvLYlGaasGt
  tr|M0R0P1|M0R0P1_HUMAN  51 VEPH-RHEGVFICRGKEDA-LVTKNLVPGESVYGEKRVSISEGddkiEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGT 135
                             6788.***********999.*******************98877899**************************************** PP

                             HHHHHHHHHTTTSEEEEEESSHHHHHHHHHHHTTSTTEEEEES-TTSGGGGTTTS--EEEEEEESSSTTHHHHHHHHHHHHEEEEEE CS
             Fibrillarin  84 tvsHvsDivgeegvvyavefsprvlrelievakkRknivPileDArkPekYralvekvDvifaDvaqpdqarilaknaklflkeggy 170
                             tvsHvsDivg++g+vyavefs+r++r+li++akkR+ni+P++eDAr+P+kYr+l+ +vDvifaDvaqpdq+ri+a+na++fl++gg+
  tr|M0R0P1|M0R0P1_HUMAN 136 TVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGH 222
                             *************************************************************************************** PP

                             EEEEEE CS
             Fibrillarin 171 llisik 176
                             ++isik
  tr|M0R0P1|M0R0P1_HUMAN 223 FVISIK 228
                             *****8 PP

>> tr|M0R1H0|M0R1H0_HUMAN  rRNA 2'-O-methyltransferase fibrillarin (Fragment) OS=Homo sapiens GN=FBL PE=2 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  156.0   0.0   4.9e-49   3.9e-45       1     102 [.      75     178 .]      75     178 .] 0.97

  Alignments for each domain:
  == domain 1  score: 156.0 bits;  conditional E-value: 4.9e-49
                             EEEECSSTTEEEEETTSSEEEEEE-SSTT--SSSSEEEEETTE....EEEEE-TTTSHHHHHHHTT-S--S--TTSEEEEESTTTSH CS
             Fibrillarin   1 veeheklegvyivkekgdarlatknlvpgekvYgEklikveee....EyRvWnpfrsKlaaailkglkelpikkgskvLYlGaasGt 83 
                             ve+h ++egv+i+++k+da l+tknlvpge+vYgEk++++ e     EyR WnpfrsKlaaail g+++++ik+g+kvLYlGaasGt
  tr|M0R1H0|M0R1H0_HUMAN  75 VEPH-RHEGVFICRGKEDA-LVTKNLVPGESVYGEKRVSISEGddkiEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGT 159
                             6788.***********999.*******************98877899**************************************** PP

                             HHHHHHHHHTTTSEEEEEE CS
             Fibrillarin  84 tvsHvsDivgeegvvyave 102
                             tvsHvsDivg++g+vyave
  tr|M0R1H0|M0R1H0_HUMAN 160 TVSHVSDIVGPDGLVYAVE 178
                             ******************8 PP

>> tr|M0R2B0|M0R2B0_HUMAN  rRNA 2'-O-methyltransferase fibrillarin (Fragment) OS=Homo sapiens GN=FBL PE=2 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  140.1   0.0   3.5e-44   2.8e-40       1      93 [.      87     181 ..      87     182 .] 0.96

  Alignments for each domain:
  == domain 1  score: 140.1 bits;  conditional E-value: 3.5e-44
                             EEEECSSTTEEEEETTSSEEEEEE-SSTT--SSSSEEEEETTE....EEEEE-TTTSHHHHHHHTT-S--S--TTSEEEEESTTTSH CS
             Fibrillarin   1 veeheklegvyivkekgdarlatknlvpgekvYgEklikveee....EyRvWnpfrsKlaaailkglkelpikkgskvLYlGaasGt 83 
                             ve+h ++egv+i+++k+da l+tknlvpge+vYgEk++++ e     EyR WnpfrsKlaaail g+++++ik+g+kvLYlGaasGt
  tr|M0R2B0|M0R2B0_HUMAN  87 VEPH-RHEGVFICRGKEDA-LVTKNLVPGESVYGEKRVSISEGddkiEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGT 171
                             6788.***********999.*******************98877899**************************************** PP

                             HHHHHHHHHT CS
             Fibrillarin  84 tvsHvsDivg 93 
                             tvsHvsDivg
  tr|M0R2B0|M0R2B0_HUMAN 172 TVSHVSDIVG 181
                             *********8 PP

>> tr|M0R2U2|M0R2U2_HUMAN  rRNA 2'-O-methyltransferase fibrillarin (Fragment) OS=Homo sapiens GN=FBL PE=2 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  108.0   0.0   2.2e-34   1.8e-30       1      81 [.      75     157 .]      75     157 .] 0.96

  Alignments for each domain:
  == domain 1  score: 108.0 bits;  conditional E-value: 2.2e-34
                             EEEECSSTTEEEEETTSSEEEEEE-SSTT--SSSSEEEEETTE....EEEEE-TTTSHHHHHHHTT-S--S--TTSEEEEESTTT CS
             Fibrillarin   1 veeheklegvyivkekgdarlatknlvpgekvYgEklikveee....EyRvWnpfrsKlaaailkglkelpikkgskvLYlGaas 81 
                             ve+h ++egv+i+++k+da l+tknlvpge+vYgEk++++ e     EyR WnpfrsKlaaail g+++++ik+g+kvLYlGaas
  tr|M0R2U2|M0R2U2_HUMAN  75 VEPH-RHEGVFICRGKEDA-LVTKNLVPGESVYGEKRVSISEGddkiEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAAS 157
                             6788.***********999.*******************98877899************************************97 PP

>> tr|Q5VZD9|Q5VZD9_HUMAN  Mitochondrial ornithine transporter 1 (Fragment) OS=Homo sapiens GN=SLC25A15 PE=2 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   9.6e-05      0.77      59     116 ..      43     100 ..      30     111 .. 0.90

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 9.6e-05
                             HHTT-S--S--TTSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSHHHHHHHHHHHT CS
             Fibrillarin  59 ilkglkelpikkgskvLYlGaasGttvsHvsDivgeegvvyavefsprvlrelievak 116
                             +++gl+++ +k+ s+v + G   Gt+++ +++i +++ +  +  f ++v+r++  + k
  tr|Q5VZD9|Q5VZD9_HUMAN  43 LYRGLTDCCLKTYSQVGFRGFYKGTSPALIANIAENSVLFMCYGFCQQVVRKVAGLDK 100
                             689********************************99989999********9987766 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (226 nodes)
Target sequences:                        88473  (35070517 residues searched)
Passed MSV filter:                      1734  (0.0195992); expected 1769.5 (0.02)
Passed bias filter:                     1400  (0.015824); expected 1769.5 (0.02)
Passed Vit filter:                       117  (0.00132244); expected 88.5 (0.001)
Passed Fwd filter:                        11  (0.000124332); expected 0.9 (1e-05)
Initial search space (Z):              88473  [actual number of targets]
Domain search space  (domZ):              11  [number of targets reported over threshold]
# CPU time: 0.65u 0.04s 00:00:00.69 Elapsed: 00:00:00.31
# Mc/sec: 25567.54
//
[ok]