# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Fibrillarin.hmm.txt # target sequence database: proteomes/Mus_musculus.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Fibrillarin [M=226] Accession: PF01269.17 Description: Fibrillarin Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8e-109 362.4 0.0 9.7e-109 362.1 0.0 1.0 1 sp|P35550|FBRL_MOUSE rRNA 2'-O-methyltransferase fibrillari 1.6e-106 354.8 0.0 1.9e-106 354.6 0.0 1.0 1 sp|Q80WS3|FBLL1_MOUSE rRNA/tRNA 2'-O-methyltransferase fibri Domain annotation for each sequence (and alignments): >> sp|P35550|FBRL_MOUSE rRNA 2'-O-methyltransferase fibrillarin OS=Mus musculus OX=10090 GN=Fbl PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 362.1 0.0 8.7e-113 9.7e-109 1 225 [. 94 320 .. 94 321 .. 0.98 Alignments for each domain: == domain 1 score: 362.1 bits; conditional E-value: 8.7e-113 EEEECSSTTEEEEETTSSEEEEEE-SSTT--SSSSEEEEETTE....EEEEE-TTTSHHHHHHHTT-S--S--TTSEEEEESTTTSHHH CS Fibrillarin 1 veeheklegvyivkekgdarlatknlvpgekvYgEklikveee....EyRvWnpfrsKlaaailkglkelpikkgskvLYlGaasGttv 85 ve+h ++egv+i+++k+da l+tknlvpge+vYgEk++++ e EyR WnpfrsKlaaail g+++++ik+g+kvLYlGaasGttv sp|P35550|FBRL_MOUSE 94 VEPH-RHEGVFICRGKEDA-LVTKNLVPGESVYGEKRVSISEGddkiEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTV 180 6788.***********999.*******************98877899****************************************** PP HHHHHHHTTTSEEEEEESSHHHHHHHHHHHTTSTTEEEEES-TTSGGGGTTTS--EEEEEEESSSTTHHHHHHHHHHHHEEEEEEEEEE CS Fibrillarin 86 sHvsDivgeegvvyavefsprvlrelievakkRknivPileDArkPekYralvekvDvifaDvaqpdqarilaknaklflkeggyllis 174 sHvsDivg++g+vyavefs+r++r+li++akkR+ni+P++eDAr+P+kYr+l+ +vDvifaDvaqpdq+ri+a+na++fl++gg+++is sp|P35550|FBRL_MOUSE 181 SHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVIS 269 ***************************************************************************************** PP EEHHHHHSSSSHHHHHHHHHHHHHHTTEEEEEEEE-TTTSTTEEEEEEEEE CS Fibrillarin 175 ikarsidvtkepeevfkeeveklkeeglkvleqvklepyekdhalvvgkyk 225 ika++id+t+++e+vf++ev+k+++e++k++eq++lepye+dha+vvg+y+ sp|P35550|FBRL_MOUSE 270 IKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYR 320 ************************************************997 PP >> sp|Q80WS3|FBLL1_MOUSE rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1 OS=Mus musculus OX=10090 GN=Fbll1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 354.6 0.0 1.7e-110 1.9e-106 1 225 [. 82 308 .. 82 309 .. 0.98 Alignments for each domain: == domain 1 score: 354.6 bits; conditional E-value: 1.7e-110 EEEECSSTTEEEEETTSSEEEEEE-SSTT--SSSSEEEEETTE....EEEEE-TTTSHHHHHHHTT-S--S--TTSEEEEESTTTSHH CS Fibrillarin 1 veeheklegvyivkekgdarlatknlvpgekvYgEklikveee....EyRvWnpfrsKlaaailkglkelpikkgskvLYlGaasGtt 84 ve+h ++egv+i ++ +da l+t n+vpg +vYgEk+++v e+ EyR+WnpfrsKlaaail g+++++ik+ skvLYlGaasGtt sp|Q80WS3|FBLL1_MOUSE 82 VEPH-RHEGVFIYRGAEDA-LVTLNMVPGVSVYGEKRVTVMENgekqEYRTWNPFRSKLAAAILGGVDQIHIKPKSKVLYLGAASGTT 167 6788.**********9999.******************998777788***************************************** PP HHHHHHHHTTTSEEEEEESSHHHHHHHHHHHTTSTTEEEEES-TTSGGGGTTTS--EEEEEEESSSTTHHHHHHHHHHHHEEEEEEEE CS Fibrillarin 85 vsHvsDivgeegvvyavefsprvlrelievakkRknivPileDArkPekYralvekvDvifaDvaqpdqarilaknaklflkeggyll 172 vsHvsDi+g++g+vyavefs+r++r+l++vakkR+ni+P+leDAr+P kYr+l+ +vDvifaDvaqpdq ri+a+na++fl++gg++l sp|Q80WS3|FBLL1_MOUSE 168 VSHVSDIIGPDGLVYAVEFSHRAGRDLVNVAKKRTNIIPVLEDARHPLKYRMLIGMVDVIFADVAQPDQSRIVALNAHTFLRNGGHFL 255 **************************************************************************************** PP EEEEHHHHHSSSSHHHHHHHHHHHHHHTTEEEEEEEE-TTTSTTEEEEEEEEE CS Fibrillarin 173 isikarsidvtkepeevfkeeveklkeeglkvleqvklepyekdhalvvgkyk 225 isika++id+t+++e+vf++ev+kl++e+lk++eq++lepye+dha+vvg+y+ sp|Q80WS3|FBLL1_MOUSE 256 ISIKANCIDSTASAEAVFASEVRKLQQENLKPQEQLTLEPYERDHAVVVGVYR 308 **************************************************997 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (226 nodes) Target sequences: 22289 (11757923 residues searched) Passed MSV filter: 407 (0.0182601); expected 445.8 (0.02) Passed bias filter: 340 (0.0152542); expected 445.8 (0.02) Passed Vit filter: 31 (0.00139082); expected 22.3 (0.001) Passed Fwd filter: 2 (8.97304e-05); expected 0.2 (1e-05) Initial search space (Z): 22289 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.18u 0.01s 00:00:00.19 Elapsed: 00:00:00.08 # Mc/sec: 33216.13 // [ok]