# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Fibrillarin.hmm.txt
# target sequence database: proteomes/Tetrahymena_thermophila.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Fibrillarin [M=226]
Accession: PF01269.17
Description: Fibrillarin
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
5.8e-107 356.5 0.0 6.6e-107 356.4 0.0 1.0 1 tr|I7MFA3|I7MFA3_TETTS rRNA 2'-O-methyltransferase fibrillar
0.0026 17.5 0.0 0.0087 15.8 0.0 1.9 1 tr|I7M457|I7M457_TETTS NOL1/NOP2/sun family protein OS=Tetra
0.0031 17.2 0.0 0.0099 15.6 0.0 1.8 1 tr|Q23UC8|Q23UC8_TETTS tRNA (adenine(58)-N(1))-methyltransfe
------ inclusion threshold ------
0.1 12.3 0.0 0.1 12.3 0.0 1.0 1 tr|Q22CK0|Q22CK0_TETTS 40S ribosomal protein S27 OS=Tetrahym
Domain annotation for each sequence (and alignments):
>> tr|I7MFA3|I7MFA3_TETTS rRNA 2'-O-methyltransferase fibrillarin OS=Tetrahymena thermophila (strain SB210) OX=312017 G
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 356.4 0.0 9.7e-111 6.6e-107 4 225 .. 69 293 .. 66 294 .] 0.98
Alignments for each domain:
== domain 1 score: 356.4 bits; conditional E-value: 9.7e-111
ECSSTTEEEEETTSSEEEEEE-SSTT--SSSSEEEEETTE....EEEEE-TTTSHHHHHHHTT-S--S--TTSEEEEESTTTSHHHH CS
Fibrillarin 4 heklegvyivkekgdarlatknlvpgekvYgEklikveee....EyRvWnpfrsKlaaailkglkelpikkgskvLYlGaasGttvs 86
+++legv+i+k++++a l+tkn+ pge+vY+Ek+++vee+ EyRvWnp+rsK+aaa++ g+++++ik+gskvLYlG asGttvs
tr|I7MFA3|I7MFA3_TETTS 69 KHRLEGVFICKGQQEA-LVTKNFFPGESVYNEKRMSVEENgekiEYRVWNPYRSKIAAAVVGGISDIHIKPGSKVLYLGGASGTTVS 154
459********99988.*********************9999********************************************* PP
HHHHHHTTTSEEEEEESSHHHHHHHHHHHTTSTTEEEEES-TTSGGGGTTTS--EEEEEEESSSTTHHHHHHHHHHHHEEEEEEEEE CS
Fibrillarin 87 HvsDivgeegvvyavefsprvlrelievakkRknivPileDArkPekYralvekvDvifaDvaqpdqarilaknaklflkeggylli 173
Hv+Divg++gvvyavefs+r++r+l+++akkR+n+vPi++DArkP++Yr lv +vDv+faDvaqpdqari+ +n+++flk+gg++li
tr|I7MFA3|I7MFA3_TETTS 155 HVADIVGPTGVVYAVEFSHRSGRDLVNMAKKRTNVVPIIGDARKPQEYRFLVGMVDVVFADVAQPDQARIMGMNCQYFLKNGGHFLI 241
*************************************************************************************** PP
EEEHHHHHSSSSHHHHHHHHHHHHHHTTEEEEEEEE-TTTSTTEEEEEEEEE CS
Fibrillarin 174 sikarsidvtkepeevfkeeveklkeeglkvleqvklepyekdhalvvgkyk 225
sika +id+t+ep+ vf++ev+klkeeglk+++q++lepye+dha+v+g+y+
tr|I7MFA3|I7MFA3_TETTS 242 SIKACCIDSTNEPAVVFAAEVQKLKEEGLKPEQQLTLEPYERDHAMVLGSYR 293
*************************************************997 PP
>> tr|I7M457|I7M457_TETTS NOL1/NOP2/sun family protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_00
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 15.8 0.0 1.3e-06 0.0087 63 112 .. 125 174 .. 119 265 .. 0.82
Alignments for each domain:
== domain 1 score: 15.8 bits; conditional E-value: 1.3e-06
-S--S--TTSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSHHHHHHHH CS
Fibrillarin 63 lkelpikkgskvLYlGaasGttvsHvsDivgeegvvyavefsprvlreli 112
+k+l +kg+kvL l G ++Di+g eg+ ++v+ ++ l
tr|I7M457|I7M457_TETTS 125 IKSLDPQKGEKVLDLCCCPGMKLCNIADIIGAEGKAFGVDINETRLNTCR 174
44555689*******************************99887665544 PP
>> tr|Q23UC8|Q23UC8_TETTS tRNA (adenine(58)-N(1))-methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 15.6 0.0 1.5e-06 0.0099 58 183 .. 130 260 .. 126 277 .. 0.74
Alignments for each domain:
== domain 1 score: 15.6 bits; conditional E-value: 1.5e-06
HHHTT-S--S--TTSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSHHHHHHHHHH..HTTSTTEEEEES-T....TSG....GGG CS
Fibrillarin 58 ailkglkelpikkgskvLYlGaasGttvsHvsDivgeegvvyavefsprvlreliev..akkRknivPileDA....rkP....ekY 134
i ++++ i++gs v+ G++s + s ++ +++eg +y+ ef + ++ ev a+ kn i D +P + Y
tr|Q23UC8|Q23UC8_TETTS 130 DISYVISKMNIQPGSIVVESGTGSASLSSSIARTIQDEGHLYTFEFNEARAKNGAEVlaAQGLKNFDVIWRDVlsngFMPipgeRVY 216
56777999***************************************9998887655226667887666555411114553332346 PP
TTTS--EEEEEEESSSTTHHHHHHHHHHHHEEEEEEEEEEEEHHHHHSS CS
Fibrillarin 135 ralvekvDvifaDvaqpdqarilaknaklflkeggyllisikarsidvt 183
+ ++ D +f D+ +p +a ++ ak lk+gg l + +i+ +
tr|Q23UC8|Q23UC8_TETTS 217 NLKEHSADAVFLDLPRPYEA---ITHAKQVLKKGGRLCC--FSPCIEQV 260
66667899999999999887...5677888898887643..35566555 PP
>> tr|Q22CK0|Q22CK0_TETTS 40S ribosomal protein S27 OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_01043
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.3 0.0 1.5e-05 0.1 117 165 .. 2 52 .. 1 79 [. 0.84
Alignments for each domain:
== domain 1 score: 12.3 bits; conditional E-value: 1.5e-05
TSTTEEEEES-TTSGGGGTTTS--EEEEEEES..SSTTHHHHHHHHHHHHE CS
Fibrillarin 117 kRknivPileDArkPekYralvekvDvifaDv..aqpdqarilaknaklfl 165
+R + Pi e+ ++ +k++ l+++ + f+Dv aq ++++++ +na+ +
tr|Q22CK0|Q22CK0_TETTS 2 ERDLLNPIYEEEKQKNKFKRLIQAPNSYFMDVkcAQCQNIQMIFSNAQSTI 52
577789*************************9778999********99755 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (226 nodes)
Target sequences: 26971 (16912921 residues searched)
Passed MSV filter: 1775 (0.0658114); expected 539.4 (0.02)
Passed bias filter: 333 (0.0123466); expected 539.4 (0.02)
Passed Vit filter: 22 (0.000815691); expected 27.0 (0.001)
Passed Fwd filter: 4 (0.000148307); expected 0.3 (1e-05)
Initial search space (Z): 26971 [actual number of targets]
Domain search space (domZ): 4 [number of targets reported over threshold]
# CPU time: 0.27u 0.01s 00:00:00.28 Elapsed: 00:00:00.11
# Mc/sec: 34748.36
//
[ok]