# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/Fibrillarin.hmm.txt
# target sequence database: proteomes/Thermococcus_kodakarensis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: Fibrillarin [M=226]
Accession: PF01269.17
Description: Fibrillarin
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
2.3e-101 334.7 0.0 2.7e-101 334.5 0.0 1.0 1 sp|Q5JFN1|FLPA_THEKO Fibrillarin-like rRNA/tRNA 2'-O-methy
0.00019 17.7 0.0 0.00025 17.3 0.0 1.1 1 tr|Q5JEE1|Q5JEE1_THEKO Protein-L-isoaspartate O-methyltransf
0.0018 14.5 0.0 0.0031 13.8 0.0 1.3 1 tr|Q5JDP5|Q5JDP5_THEKO tRNA/rRNA cytosine-C5-methylase, NOL1
0.0044 13.3 0.0 0.0085 12.3 0.0 1.4 1 tr|Q5JEW7|Q5JEW7_THEKO tRNA/rRNA cytosine-C5-methylase, NOL1
Domain annotation for each sequence (and alignments):
>> sp|Q5JFN1|FLPA_THEKO Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 334.5 0.0 4.7e-104 2.7e-101 2 223 .. 4 224 .. 3 226 .] 0.97
Alignments for each domain:
== domain 1 score: 334.5 bits; conditional E-value: 4.7e-104
EEECSSTTEEEEE.TTSSEEEEEE-SSTT--SSSSEEEEETTEEEEEE-TTTSHHHHHHHTT-S--S--TTSEEEEESTTTSHHHHHHH CS
Fibrillarin 2 eeheklegvyivk.ekgdarlatknlvpgekvYgEklikveeeEyRvWnpfrsKlaaailkglkelpikkgskvLYlGaasGttvsHvs 89
++h ++ gvyiv ++g++++atknlvpg++vYgE+++k e+eEyR+Wnp rsKl+aail+glk++pik+gs vLYlG+asGtt+sHvs
sp|Q5JFN1|FLPA_THEKO 4 KKH-RFPGVYIVIdDDGSEKIATKNLVPGQRVYGERVVKFEGEEYRIWNPTRSKLGAAILNGLKNFPIKPGSTVLYLGVASGTTASHVS 91
566.*******99899999********************************************************************** PP
HHHTTTSEEEEEESSHHHHHHHHHHHTTSTTEEEEES-TTSGGGGTTTS--EEEEEEESSSTTHHHHHHHHHHHHEEEEEEEEEEEEHH CS
Fibrillarin 90 DivgeegvvyavefsprvlrelievakkRknivPileDArkPekYralvekvDvifaDvaqpdqarilaknaklflkeggyllisikar 178
Divg eg+v++vefsprvlrel+ ++++R+nivPil+DA+kPe Yralv+kvDvif+Dvaqp+qa+il++nak++lk+ggy +is+k+r
sp|Q5JFN1|FLPA_THEKO 92 DIVGWEGKVFGVEFSPRVLRELVPLVEERRNIVPILGDATKPEGYRALVPKVDVIFEDVAQPTQAKILIDNAKVYLKSGGYGMISVKSR 180
***************************************************************************************** PP
HHHSSSSHHHHHHHHHHHHHHTTEEEEEEEE-TTTSTTEEEEEEE CS
Fibrillarin 179 sidvtkepeevfkeeveklkeeglkvleqvklepyekdhalvvgk 223
sidvtkepe+vfke +++l++ ++v+e ++lepyekdhal+v++
sp|Q5JFN1|FLPA_THEKO 181 SIDVTKEPEQVFKEVEKELST-YFEVVERLSLEPYEKDHALFVVR 224
**************9999986.5******************9986 PP
>> tr|Q5JEE1|Q5JEE1_THEKO Protein-L-isoaspartate O-methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA-918
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 17.3 0.0 4.3e-07 0.00025 62 129 .. 69 136 .. 61 151 .. 0.78
Alignments for each domain:
== domain 1 score: 17.3 bits; conditional E-value: 4.3e-07
T-S--S--TTSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSHHHHHHHHHHHTTS...TTEEEEES-TT CS
Fibrillarin 62 glkelpikkgskvLYlGaasGttvsHvsDivgeegvvyavefsprvlrelievakkR...knivPileDAr 129
l+ +k+g +vL +G++sG ++ +s++v+ vy++e p + e+ + +R kn+ il+D +
tr|Q5JEE1|Q5JEE1_THEKO 69 MLELADLKPGMNVLEIGTGSGWNAALISELVK--TDVYTIERIPELV-EFARRNLERagvKNVHVILGDGT 136
4666789************************9..78*****999865.44444444423368888888876 PP
>> tr|Q5JDP5|Q5JDP5_THEKO tRNA/rRNA cytosine-C5-methylase, NOL1/NOP2/Sun family OS=Thermococcus kodakarensis (strain AT
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 13.8 0.0 5.3e-06 0.0031 69 115 .. 249 295 .. 234 311 .. 0.86
Alignments for each domain:
== domain 1 score: 13.8 bits; conditional E-value: 5.3e-06
-TTSEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSHHHHHHHHHHH CS
Fibrillarin 69 kkgskvLYlGaasGttvsHvsDivgeegvvyavefsprvlrelieva 115
k+g+ v+ l aa G +H++++++++g++ya ++ + ++ + ev
tr|Q5JDP5|Q5JDP5_THEKO 249 KPGETVVDLAAAPGGKTAHMAELMENRGKIYAFDVDSARIKRMKEVL 295
89******************************999877777766665 PP
>> tr|Q5JEW7|Q5JEW7_THEKO tRNA/rRNA cytosine-C5-methylase, NOL1/NOP2/Sun family, containing RNA-binding PUA domain OS=T
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 12.3 0.0 1.5e-05 0.0085 72 130 .. 200 260 .. 182 265 .. 0.80
Alignments for each domain:
== domain 1 score: 12.3 bits; conditional E-value: 1.5e-05
SEEEEESTTTSHHHHHHHHHHTTTSEEEEEESSHHHHHHHHHHHTT..STTEEEEES-TTS CS
Fibrillarin 72 skvLYlGaasGttvsHvsDivgeegvvyavefsprvlrelievakk..RknivPileDArk 130
+ ++ + aa G sH++ +++++g + a++ s lr++ e k+ kn+ i DArk
tr|Q5JEW7|Q5JEW7_THEKO 200 DLIIDMAAAPGGKTSHIAQLMQNRGEIIAIDKSRNRLRKMEEELKRlgVKNVRLIHMDARK 260
4567788999****************************99876654224777777777775 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (226 nodes)
Target sequences: 2301 (637680 residues searched)
Passed MSV filter: 90 (0.0391134); expected 46.0 (0.02)
Passed bias filter: 74 (0.0321599); expected 46.0 (0.02)
Passed Vit filter: 14 (0.00608431); expected 2.3 (0.001)
Passed Fwd filter: 4 (0.00173837); expected 0.0 (1e-05)
Initial search space (Z): 2301 [actual number of targets]
Domain search space (domZ): 4 [number of targets reported over threshold]
# CPU time: 0.03u 0.00s 00:00:00.03 Elapsed: 00:00:00.02
# Mc/sec: 7205.78
//
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