# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/FtsJ.hmm.txt # target sequence database: proteomes/Mus_musculus.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: FtsJ [M=177] Accession: PF01728.18 Description: FtsJ-like methyltransferase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.1e-68 231.1 0.1 1.5e-68 230.7 0.1 1.1 1 tr|Q8CBC7|Q8CBC7_MOUSE Putative tRNA (cytidine(32)/guanosine 5.7e-56 189.7 0.0 1.1e-55 188.9 0.0 1.5 1 sp|Q9DBE9|SPB1_MOUSE pre-rRNA processing protein FTSJ3 OS= 1.9e-51 175.0 0.0 2.2e-51 174.8 0.0 1.0 1 sp|Q9CPY0|MRM2_MOUSE rRNA methyltransferase 2, mitochondri 1.1e-38 133.5 0.0 2.5e-38 132.2 0.0 1.7 1 sp|Q9DBC3|CMTR1_MOUSE Cap-specific mRNA (nucleoside-2'-O-)- 1.7e-29 103.5 0.1 2.2e-27 96.6 0.0 2.5 2 sp|Q8BWQ4|CMTR2_MOUSE Cap-specific mRNA (nucleoside-2'-O-)- 1.9e-06 28.4 0.0 3.8e-06 27.4 0.0 1.4 1 sp|Q7TS68|NSUN6_MOUSE Putative methyltransferase NSUN6 OS=M 0.00068 20.1 0.0 0.0012 19.3 0.0 1.4 1 sp|Q8K4F6|NSUN5_MOUSE Probable 28S rRNA (cytosine-C(5))-met 0.0018 18.7 0.0 0.0035 17.8 0.0 1.4 1 sp|Q922K7|NOP2_MOUSE Probable 28S rRNA (cytosine-C(5))-met 0.0062 17.0 0.0 0.015 15.7 0.0 1.6 1 sp|Q8CCT7|NSUN3_MOUSE tRNA (cytosine(34)-C(5))-methyltransf 0.0065 16.9 0.4 0.022 15.2 0.1 2.0 2 sp|Q922H1|ANM3_MOUSE Protein arginine N-methyltransferase ------ inclusion threshold ------ 0.021 15.2 0.0 0.049 14.1 0.0 1.6 1 sp|Q1HFZ0|NSUN2_MOUSE tRNA (cytosine(34)-C(5))-methyltransf 0.023 15.1 0.1 0.062 13.7 0.1 1.7 1 sp|P35550|FBRL_MOUSE rRNA 2'-O-methyltransferase fibrillar 0.027 14.9 0.0 0.046 14.1 0.0 1.4 1 sp|Q91WU5|AS3MT_MOUSE Arsenite methyltransferase OS=Mus mus 0.044 14.2 0.0 0.092 13.2 0.0 1.5 1 sp|P23506|PIMT_MOUSE Protein-L-isoaspartate(D-aspartate) O 0.093 13.1 0.0 0.18 12.2 0.0 1.6 1 sp|Q6NZB1|ANM6_MOUSE Protein arginine N-methyltransferase Domain annotation for each sequence (and alignments): >> tr|Q8CBC7|Q8CBC7_MOUSE Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase OS=Mus musculus OX=10090 GN # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 230.7 0.1 9.8e-72 1.5e-68 1 177 [] 21 199 .. 21 199 .. 0.98 Alignments for each domain: == domain 1 score: 230.7 bits; conditional E-value: 9.8e-72 TTSHHHHHHHHHHHHH--S-TT-EEEEES-TT-HHHHHHTTT.....-SEEEEEESS-----TT-EEEE--TTSSSHHHHHHHHHHH CS FtsJ 1 yrsRsayKLleidekfklfkpgktvvDlgaaPGgwsqvllqrlga..kgkvvavDlqpmaplpgvttiqgditdpetiekikealse 85 +r+Rsa+KLl++de+f+lfk +k++vDl+aaPG+wsqvl+q++g +g+vvavDlq maplpgv +iqgdit+ +t+++i +++++ tr|Q8CBC7|Q8CBC7_MOUSE 21 WRARSAFKLLQLDEEFQLFKGVKRAVDLCAAPGSWSQVLSQKVGGqgSGQVVAVDLQAMAPLPGVIQIQGDITQLSTAKEIIQHFEG 107 79*****************************************76556*************************************** PP SSEEEEEE-------S-HHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEE-STTHHHHHHHHGGGEEEEEEE----------EEEE CS FtsJ 86 rkvdlvvsDgapdvsgvhdldeylqsqLllaalelalkllkpggtfvlkifrgeeteallkqlkkfFekvsvvkPkssrsesseefl 172 ++dlvv+Dgapdv+g hd+dey+q+qLllaal++a+++lk gg+fv+kifrg++++ l++ql+ fF++v ++kPkssr++s e+f tr|Q8CBC7|Q8CBC7_MOUSE 108 CPADLVVCDGAPDVTGLHDVDEYMQAQLLLAALNIATHVLKLGGCFVAKIFRGRDVTLLYSQLRIFFSSVLCAKPKSSRNSSIEAFA 194 *************************************************************************************** PP EEEEE CS FtsJ 173 vcrgf 177 vc+g+ tr|Q8CBC7|Q8CBC7_MOUSE 195 VCQGY 199 **986 PP >> sp|Q9DBE9|SPB1_MOUSE pre-rRNA processing protein FTSJ3 OS=Mus musculus OX=10090 GN=Ftsj3 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 188.9 0.0 7.1e-59 1.1e-55 1 177 [] 24 200 .. 24 200 .. 0.99 Alignments for each domain: == domain 1 score: 188.9 bits; conditional E-value: 7.1e-59 TTSHHHHHHHHHHHHH--S-TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS-----TT-EEEE--TTSSSHHHHHHHHHHHSSEE CS FtsJ 1 yrsRsayKLleidekfklfkpgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpmaplpgvttiqgditdpetiekikealserkvd 89 yrsRsa+KL++++ +f+++++ ++ +Dl+aaPGgw qv+++ + ++ +v+vDl p++plp+v t+q dit+++ ++++++ l+ kvd sp|Q9DBE9|SPB1_MOUSE 24 YRSRSAFKLIQLNRRFQFLQKARALLDLCAAPGGWLQVAAKFMPVSSLIVGVDLVPIKPLPNVVTLQEDITTERCRQALRKELKTWKVD 112 9****************99************************999******************************************* PP EEEE-------S-HHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEE-STTHHHHHHHHGGGEEEEEEE----------EEEEEEEEE CS FtsJ 90 lvvsDgapdvsgvhdldeylqsqLllaalelalkllkpggtfvlkifrgeeteallkqlkkfFekvsvvkPkssrsesseeflvcrgf 177 +v+ Dgap+v ++ d+y q++L l al+la++ l++gg+f++k+fr+++ + ll ++++F++v+ +kP++sr es+e+f+vc+gf sp|Q9DBE9|SPB1_MOUSE 113 VVLNDGAPNVGASWVHDAYSQAHLTLMALRLACDFLARGGCFITKVFRSRDYQPLLWIFQQLFHRVQATKPQASRHESAEIFVVCQGF 200 **************************************************************************************98 PP >> sp|Q9CPY0|MRM2_MOUSE rRNA methyltransferase 2, mitochondrial OS=Mus musculus OX=10090 GN=Mrm2 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 174.8 0.0 1.5e-54 2.2e-51 1 176 [. 52 236 .. 52 237 .. 0.96 Alignments for each domain: == domain 1 score: 174.8 bits; conditional E-value: 1.5e-54 TTSHHHHHHHHHHHHH--S-TT-EEEEES-TT-HHHHHHTTT.......-....SEEEEEESS-----TT-EEE.E--TTSSSHHHHHH CS FtsJ 1 yrsRsayKLleidekfklfkpgktvvDlgaaPGgwsqvllqrlga....k....gkvvavDlqpmaplpgvtti.qgditdpetiekik 80 yr+Rsa+KLle++ek+++++pg +v+D+gaaPG+wsqv++qr++a + g v++vDl ++ pl g t++ +d+tdp+t +ki+ sp|Q9CPY0|MRM2_MOUSE 52 YRCRSAFKLLEMNEKHQILRPGLRVLDCGAAPGAWSQVAVQRVNAtgadSsspvGFVLGVDLLHIFPLAGATFLcPADVTDPRTFQKIL 140 9******************************************7755541566799******************99************* PP HHHHHSSEEEEEE-------S-HHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEE-STTHHHHHHHHGGGEEEEEEE----------E CS FtsJ 81 ealserkvdlvvsDgapdvsgvhdldeylqsqLllaalelalkllkpggtfvlkifrgeeteallkqlkkfFekvsvvkPkssrsesse 169 e+l r++d+++sD+ap+ +g++dld+ + ++L+l + +a+++l pggt+++k++ g+++ l k+l + F++ +vvkP++sr+esse sp|Q9CPY0|MRM2_MOUSE 141 ELLPSRRADVILSDMAPNATGIRDLDHDKLISLCLTLVDMAVDILHPGGTLLCKTWAGSKSHLLQKRLTQEFQSTRVVKPEASRKESSE 229 ****************************************************************99*********************** PP EEEEEEE CS FtsJ 170 eflvcrg 176 ++l++++ sp|Q9CPY0|MRM2_MOUSE 230 VYLLATQ 236 ***9987 PP >> sp|Q9DBC3|CMTR1_MOUSE Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 OS=Mus musculus OX=10090 GN=Cmtr1 PE= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 132.2 0.0 1.7e-41 2.5e-38 2 176 .. 232 447 .. 231 448 .. 0.85 Alignments for each domain: == domain 1 score: 132.2 bits; conditional E-value: 1.7e-41 TSHHHHHHHHHHHHH-.-S-.TT-E...............EEEES-TT-HHHHHHTTT...-SEEEEEES.S--.............- CS FtsJ 2 rsRsayKLleidekfk.lfk.pgkt...............vvDlgaaPGgwsqvllqrlgakgkvvavDl.qpm.............a 58 +R+a+K++++d f+ +f+ p + + D++a+PGg+s+++l+r + ++k ++++l +p+ sp|Q9DBC3|CMTR1_MOUSE 232 LNRAAMKMANMDFVFDrMFTnPLDSsgkpllkesdidllyFADVCAGPGGFSEYVLWRKKWHAKGFGMTLkGPNdfkledfysasseL 319 68*************8666533322555666677777777******************75589*******878887666555544430 PP --TT-EEE...........E--TTSSSHHHHHHHHHHH....SSEEEEEE-------S-HHHHHHHHHHHHHHHHHHHHHHEEEEEEE CS FtsJ 59 plpgvtti...........qgditdpetiekikealse....rkvdlvvsDgapdvsgvhdldeylqsqLllaalelalkllkpggtf 131 + gdit+pe+i+++++++ + ++v++v++Dg+++v+g+++l+e+l+ qLll+++ +al+++++gg+f sp|Q9DBC3|CMTR1_MOUSE 320 -------FepyygeggvdgDGDITRPENINAFRNFVLDntdrKGVHFVMADGGFSVEGQENLQEILSKQLLLCQFLMALSVVRTGGHF 400 .......144455555599***********99976666666699******************************************** PP EEEEE-.STTHH.HHHHHHGGGEEEEEEE----------EEEEEEEE CS FtsJ 132 vlkifr.geete.allkqlkkfFekvsvvkPkssrsesseeflvcrg 176 v+k+f+ ++ ++ +l++ l ++Fe+v ++kP +sr+++se+++vc+g sp|Q9DBC3|CMTR1_MOUSE 401 VCKTFDlFTPFSvGLIYLLYCCFERVCLFKPITSRPANSERYVVCKG 447 *******999999********************************97 PP >> sp|Q8BWQ4|CMTR2_MOUSE Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 OS=Mus musculus OX=10090 GN=Cmtr2 PE= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 96.6 0.0 1.5e-30 2.2e-27 3 177 .] 112 320 .. 110 320 .. 0.85 2 ? 4.2 0.0 0.034 51 96 162 .. 608 675 .. 584 690 .. 0.80 Alignments for each domain: == domain 1 score: 96.6 bits; conditional E-value: 1.5e-30 SHHHHHHHHHHHHH--S-TT......-EEEEES-TT-HHHHHHTTT........-SEEEEEESS--...........---TT-EEE.. CS FtsJ 3 sRsayKLleidekfklfkpg......ktvvDlgaaPGgwsqvllqrlga.....kgkvvavDlqpm...........aplpgvtti.. 66 +++++K +ei+ f l+ ++ + ++l+ aPG+++ l++ l+ ++ +va l+p+ + sp|Q8BWQ4|CMTR2_MOUSE 112 TQAWCKFQEILCSFPLIPQEafqsgrLNSLHLCEAPGAFIASLNHYLKShrfpcEWSWVANSLNPYheandnlrmitD-------Drl 192 57999*********98754334444455******************965555556***********765555544441.......033 PP ..............E--TTSSSHHHHHHHHHHH.SSEEEEEE-------S-HHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEE-.S CS FtsJ 67 ..............qgditdpetiekikealse.rkvdlvvsDgapdvsgvhdldeylqsqLllaalelalkllkpggtfvlkifr.g 138 +gdi++ + ++++ls+ ++++lv++Dg++d++g+ +e+l s+L + +al +l+ gg+fvlk+f+ + sp|Q8BWQ4|CMTR2_MOUSE 193 mantlhcwyfgpdnTGDIMTLKYLTGLQDFLSGmSPIHLVTADGSFDCQGNPGEQEALVSSLHYCEAVTALITLGDGGSFVLKMFTlF 280 344445558999999999999999999999998889***************999999999**************************** PP TTHH.HHHHHHGGGEEEEEEE----------EEEEEEEEE CS FtsJ 139 eete.allkqlkkfFekvsvvkPkssrsesseeflvcrgf 177 e+++ +l++ l++ F++v+v+kP++s+ ++se+++vc+++ sp|Q8BWQ4|CMTR2_MOUSE 281 EHCSvNLMYLLNCSFDQVHVFKPATSKAGNSEVYVVCLRY 320 ****9********************************975 PP == domain 2 score: 4.2 bits; conditional E-value: 0.034 -----S-HHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEE-.STTHH.HHHHHHGGGEEEEEEE---- CS FtsJ 96 apdvsgvhdldeylqsqLllaalelalkllkpggtfvlkifr.geete.allkqlkkfFekvsvvkPks 162 a+++s+ hd d + q +L+l l +l+ l +g+++vl i+ ++++ +l l +F+ ++ P s sp|Q8BWQ4|CMTR2_MOUSE 608 AFSCSLLHDGDPAYQ-HLFLDCLLHSLRRLHRGDVMVLPILScFTRFMaGLTFVLHGCFRFITFSCPTS 675 4589999*******9.7***********************99877887455555999998887777765 PP >> sp|Q7TS68|NSUN6_MOUSE Putative methyltransferase NSUN6 OS=Mus musculus OX=10090 GN=Nsun6 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.4 0.0 2.6e-09 3.8e-06 21 150 .. 234 390 .. 223 392 .. 0.75 Alignments for each domain: == domain 1 score: 27.4 bits; conditional E-value: 2.6e-09 TT-EEEEES-TT-HHHHHHTTT...-SEEEEEES..S--......---TT-EEE...E--TTSSSHHHHHHHHHHH.....SSEEEEE CS FtsJ 21 pgktvvDlgaaPGgwsqvllqrlgakgkvvavDl..qpm......aplpgvtti...qgditdpetiekikealse.....rkvdlvv 92 pg++++D +aaPGg + + ++ kg v+a+D ++ a l g+++i + d t+ + ++ ++ + +d ++ sp|Q7TS68|NSUN6_MOUSE 234 PGEKILDMCAAPGGKTTHTAALMQDKGEVIALDKilTKVnklkqnASLLGLHSIrafCFDATKALKLDTTDGIEGGppflpESFDRII 321 8999*******************999*******8534446555443333444445559999988888877765555888887777777 PP E----.......---S-HHHHHHHHH.HHHHHHHHHHHHHEEEEEEEEEEEE-...STTHHHHHHHHGG CS FtsJ 93 sDgap.......dvsgvhdldeylqs.qLllaalelalkllkpggtfvlkifr...geeteallkqlkk 150 D ++ +++l+e+++ L ++ l++a++llkpgg++v +++ e+ e+++ +l++ sp|Q7TS68|NSUN6_MOUSE 322 LDAPCsgmgqrpNMACTWTLKEVTSYqPLQRKLLHVAVQLLKPGGVLVYSTCTitlAENEEQVAWALRT 390 7743234444559999999999999768********************887777667777787777765 PP >> sp|Q8K4F6|NSUN5_MOUSE Probable 28S rRNA (cytosine-C(5))-methyltransferase OS=Mus musculus OX=10090 GN=Nsun5 PE=2 SV= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.3 0.0 7.8e-07 0.0012 21 101 .. 226 312 .. 207 364 .. 0.79 Alignments for each domain: == domain 1 score: 19.3 bits; conditional E-value: 7.8e-07 TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS--......---...TT-EEE...E--TTSSSHHHHHHHHHHHSSEEEEEE--- CS FtsJ 21 pgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm......apl...pgvtti...qgditdpetiekikealserkvdlvvsDga 96 pg +v+D +aaPG+ + +++ l+++gk++a+D+ + l gv++ + d+++ + ++ ++v+ ++ D + sp|Q8K4F6|NSUN5_MOUSE 226 PGSHVIDACAAPGNKTSYIAALLKNQGKIFAFDQDAKrlaamaT-LvarAGVSCCelaEKDFLTVSPSDQRY-----SQVQYILLDPS 307 7899*******************999********8776765541.134477777788888888877777444.....35888888877 PP ----S CS FtsJ 97 pdvsg 101 + sg sp|Q8K4F6|NSUN5_MOUSE 308 CSGSG 312 54444 PP >> sp|Q922K7|NOP2_MOUSE Probable 28S rRNA (cytosine-C(5))-methyltransferase OS=Mus musculus OX=10090 GN=Nop2 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.8 0.0 2.3e-06 0.0035 21 132 .. 369 498 .. 350 518 .. 0.67 Alignments for each domain: == domain 1 score: 17.8 bits; conditional E-value: 2.3e-06 TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS-----TT-EEEE--TTSSSHHHHHHHHHHH.......SSEEEEEE-------S- CS FtsJ 21 pgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpmaplpgvttiqgditdpetiekikealse.......rkvdlvvsDgapdvsgv 102 + ++++D ++aPGg + +++q ++++g+++a D + ++++++ g+ + + ++i + ++ ++d v+ D + +gv sp|Q922K7|NOP2_MOUSE 369 EHERILDMCCAPGGKTSYIAQLMKNTGVILANDANA----DRLKSVVGNLHRLGVTNTIISHYDGrqfpkvvGGFDRVLLDAPCSGTGV 453 45679******************8878888888776....5666666666666666666655555555556544555555554444444 PP HHHHHHHH...............HHHHHHHHHHHHHHEEEEEEEE CS FtsJ 103 hdldeylq...............sqLllaalelalkllkpggtfv 132 ++d +++ +Lll+a+ + k+gg +v sp|Q922K7|NOP2_MOUSE 454 ISKDPAVKtnkdekdiqrcahlqKELLLSAIDSVNAASKTGGYLV 498 444444444444444444444444677777766666666666665 PP >> sp|Q8CCT7|NSUN3_MOUSE tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial OS=Mus musculus OX=10090 GN=Nsun3 PE # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.7 0.0 1e-05 0.015 20 138 .. 130 269 .. 108 285 .. 0.63 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 1e-05 -TT-EEEEES-TT-HHHHHHTTT..............-SEEEEEESS-----TT-EEEE--TTSSSHHHHHHHHHHHSSEEEEEE--- CS FtsJ 20 kpgktvvDlgaaPGgwsqvllqrl...........gakgkvvavDlqpmaplpgvttiqgditdpetiekikealserkvdlvvsDga 96 + g++v+Dl+aaPGg s llq ++g+++ +l + p p +++i+ +d + + ++a +d v+ D sp|Q8CCT7|NSUN3_MOUSE 130 RDGEAVLDLCAAPGGKSVALLQCAypgyllcneydRPRGRWLRQTLESFIPQPLINVIKVSELDGREMGDAQPA----TFDKVLVDAP 213 46789***************999866666654443225899999999988888888887666666666666664....3777777753 PP -..........---S-HHHHHHHH..........HHHHHHHHHHHHHHEEEEEEEEEEEE-..S CS FtsJ 97 p..........dvsgvhdldeylq..........sqLllaalelalkllkpggtfvlkifr..g 138 d +++ +y+ ++L+++a++ l+pgg +v +++ + sp|Q8CCT7|NSUN3_MOUSE 214 CsndrswlfssD----SQKAAYRIhqrknlpvlqVELVRSAIKA----LRPGGLLVYSTCTlsK 269 344444443330....2222222233433322225555555555....8999998887777543 PP >> sp|Q922H1|ANM3_MOUSE Protein arginine N-methyltransferase 3 OS=Mus musculus OX=10090 GN=Prmt3 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.3 0.0 3.5 5.2e+03 53 81 .. 180 208 .. 179 221 .. 0.80 2 ! 15.2 0.1 1.5e-05 0.022 17 70 .. 249 310 .. 238 361 .. 0.72 Alignments for each domain: == domain 1 score: -2.3 bits; conditional E-value: 3.5 ESS-----TT-EEEE--TTSSSHHHHHHH CS FtsJ 53 Dlqpmaplpgvttiqgditdpetiekike 81 Dlq+m+++ + +++ d+++ + +i + sp|Q922H1|ANM3_MOUSE 180 DLQKMKQFAQDFVMNVDVRTCSSTTTIAD 208 89999999999999999988777776665 PP == domain 2 score: 15.2 bits; conditional E-value: 1.5e-05 --S-TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS--...........---.TT-EEEE--T CS FtsJ 17 klfkpgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm...........apl.pgvttiqgdi 70 ++f ++k v+D+g+++G s ++++ ga +kv+avD+ ++ + l + + +i+g i sp|Q922H1|ANM3_MOUSE 249 HIF-KDKVVLDVGCGTGILSMFAAKV-GA-KKVIAVDQSEIlyqamdiirlnK-LeDTIVLIKGKI 310 566.6889***************999.88.9*******999774433332211.123333334433 PP >> sp|Q1HFZ0|NSUN2_MOUSE tRNA (cytosine(34)-C(5))-methyltransferase OS=Mus musculus OX=10090 GN=Nsun2 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.1 0.0 3.3e-05 0.049 20 137 .. 175 322 .. 146 340 .. 0.66 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 3.3e-05 -TT-EEEEES-TT-HHHHHHTTT..........-SEEEEEESS--.........---..TT-EEEE--TTSSSHHHHHHHHHHHSS.. CS FtsJ 20 kpgktvvDlgaaPGgwsqvllqrlga.......kgkvvavDlqpm.........apl..pgvttiqgditdpetiekikealserk.. 87 +p ++++D +aaPG+ + l + l+a +g v+a D+ + + l p + +++ d + +++rk sp|Q1HFZ0|NSUN2_MOUSE 175 EPHHKILDMCAAPGSKTTQLIEMLHAdmsvpfpEGFVIANDVDNKrcyllvhqaKRLssPCIMVVNHDASSIPRLT--V-DVDGRKei 259 57899*******************77666666669*******7765788876643333444444455554333332..1.12222223 PP ..EEEEEE----........---S-HHHHHHHH......HHHHHHHHHHHH...HHEEEEEEEEEEEE- CS FtsJ 88 ..vdlvvsDgap........dvsgvhdldeylq......sqLllaalelal...kllkpggtfvlkifr 137 d +++D+ + +d ++ +qL +l++a+ ++l++gg +v ++ sp|Q1HFZ0|NSUN2_MOUSE 260 lfYDRILCDVPCsgdgtmrkN------IDVWKKwttlnsLQLHGLQLRIATrgaEQLAEGGRMVYSTCS 322 338999999754443333333......444444555544788888888877333588889988877666 PP >> sp|P35550|FBRL_MOUSE rRNA 2'-O-methyltransferase fibrillarin OS=Mus musculus OX=10090 GN=Fbl PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.1 4.2e-05 0.062 13 99 .. 158 248 .. 146 301 .. 0.79 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 4.2e-05 HHHH--S-TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS--.........---TT-EEEE--TTSSSHHHHHHHHHHHSSEEEEE CS FtsJ 13 dekfklfkpgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm.........aplpgvttiqgditdpetiekikealserkvdlvv 92 ++ + +kpg +v+ lgaa G ++ +g++g v+av + +++ ++ + d ++p + +++ vd++ sp|P35550|FBRL_MOUSE 158 VDQIH-IKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRsgrdlinlaKKRTNIIPVIEDARHPHKYRMLIA-----MVDVIF 240 57788.89**********************************999788666543344555555*********999885.....49**** PP E---.--- CS FtsJ 93 sDga.pdv 99 +D+a pd sp|P35550|FBRL_MOUSE 241 ADVAqPDQ 248 ***94443 PP >> sp|Q91WU5|AS3MT_MOUSE Arsenite methyltransferase OS=Mus musculus OX=10090 GN=As3mt PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.1 0.0 3.1e-05 0.046 23 110 .. 73 170 .. 45 194 .. 0.81 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 3.1e-05 -EEEEES-TT-HHHHHHTTT...-SEEEEEESS--.................---TT-EEEE--TTSSSHHHHHHHHHHHSSEEEEEE CS FtsJ 23 ktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm.................aplpgvttiqgditdpetiekikealserkvdlvvs 93 +++Dlg++ G + vl+q +g+kg+v ++D+ ++ + p+vt+++g i + + + + + d+v+s sp|Q91WU5|AS3MT_MOUSE 73 CRILDLGSGSGRDCYVLSQLVGEKGHVTGIDMTEVqvevaktylehhmekfgFQAPNVTFLHGRIEKLAEAGIQS-----ESYDIVIS 155 469********************************9999999998777554434499999999999998887444.....46899999 PP -------S-HHHHHHHH CS FtsJ 94 Dgapdvsgvhdldeylq 110 + +++v d++++lq sp|Q91WU5|AS3MT_MOUSE 156 NCV--INLVPDKQQVLQ 170 887..555556555555 PP >> sp|P23506|PIMT_MOUSE Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Mus musculus OX=10090 GN=Pcmt1 PE=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.0 6.2e-05 0.092 16 96 .. 73 144 .. 65 184 .. 0.66 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 6.2e-05 H--S-TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS-----TT-EEEE--TTSSSHHHHHHHHHHHSSEEEEEE--- CS FtsJ 16 fklfkpgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpmaplpgvttiqgditdpetiekikealserkvdlvvsDga 96 f+ +++g +++D+g++ G + + ++ +g++gkv+++D + +++ it+ ++ + ++ ls +v lvv Dg sp|P23506|PIMT_MOUSE 73 FDQLHEGAKALDVGSGSGILTACFARMVGNSGKVIGIDHIK-------ELVDDSITNVKKDDPML--LSSGRVRLVVGDGR 144 555679***********************9********866.......23333333333333222..23345666666665 PP >> sp|Q6NZB1|ANM6_MOUSE Protein arginine N-methyltransferase 6 OS=Mus musculus OX=10090 GN=Prmt6 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.0 0.00012 0.18 21 96 .. 85 245 .. 70 308 .. 0.61 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.00012 TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS--...........---.TT-EEEE--TTSSSHHHHHHHHHHH............ CS FtsJ 21 pgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm...........apl.pgvttiqgditdpetiekikealse............ 85 +gktv+D+ga++G s +++q ga +v+av + l ++v+++ g + + e e++ +se sp|Q6NZB1|ANM6_MOUSE 85 RGKTVLDVGAGTGILSIFCAQA-GA-RRVYAVEASAIwqqarevvrlnG-LeDRVHVLPGPVETVELPERVDAIVSEwmgygllhesml 170 799*******************.88.9******9999876554443322.135666666666555555555555555555566666666 PP ................................................................SSEEEEEE--- CS FtsJ 86 ................................................................rkvdlvvsDga 96 ++vv D++ sp|Q6NZB1|ANM6_MOUSE 171 ssvlhartkwlkegglllpasaelfvapisdqmlewrlgfwsqvkqhygvdmscmesfatrclmGHSEIVVQDLS 245 666666666666666666655555555555555555555555555555555555555555555555555555555 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (177 nodes) Target sequences: 22289 (11757923 residues searched) Passed MSV filter: 559 (0.0250796); expected 445.8 (0.02) Passed bias filter: 475 (0.021311); expected 445.8 (0.02) Passed Vit filter: 39 (0.00174974); expected 22.3 (0.001) Passed Fwd filter: 15 (0.000672978); expected 0.2 (1e-05) Initial search space (Z): 22289 [actual number of targets] Domain search space (domZ): 15 [number of targets reported over threshold] # CPU time: 0.22u 0.01s 00:00:00.23 Elapsed: 00:00:00.09 # Mc/sec: 23123.92 // [ok]