# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/FtsJ.hmm.txt # target sequence database: proteomes/Natronomonas_moolapensis.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: FtsJ [M=177] Accession: PF01728.18 Description: FtsJ-like methyltransferase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 7.4e-56 186.4 0.0 8.7e-56 186.1 0.0 1.1 1 tr|M1XTZ7|M1XTZ7_NATM8 Ribosomal RNA large subunit methyltra 1.9e-06 25.4 0.0 2.9e-06 24.8 0.0 1.2 1 tr|M1XPJ5|M1XPJ5_NATM8 tRNA/rRNA cytosine-C5-methylase OS=Na 0.0009 16.7 0.0 0.0014 16.1 0.0 1.2 1 tr|M1XS10|M1XS10_NATM8 Probable rRNA methyltransferase OS=Na 0.0046 14.4 0.0 0.011 13.2 0.0 1.5 1 tr|M1Y1P2|M1Y1P2_NATM8 Probable S-adenosylmethionine-depende 0.0073 13.8 0.0 0.013 13.0 0.0 1.5 1 tr|M1XL08|M1XL08_NATM8 Probable arsenite(III)-methyltransfer 0.0084 13.6 0.0 0.013 13.0 0.0 1.3 1 tr|M1XTN7|M1XTN7_NATM8 Probable S-adenosylmethionine-depende 0.0092 13.4 0.0 0.012 13.1 0.0 1.2 1 tr|M1XNA3|M1XNA3_NATM8 Probable demethylmenaquinone methyltr ------ inclusion threshold ------ 0.017 12.6 0.0 0.31 8.5 0.0 2.1 2 tr|M1XP07|M1XP07_NATM8 Probable S-adenosylmethionine-depende 0.018 12.5 0.0 0.024 12.1 0.0 1.2 1 tr|M1Y4D2|M1Y4D2_NATM8 Probable S-adenosylmethionine-depende Domain annotation for each sequence (and alignments): >> tr|M1XTZ7|M1XTZ7_NATM8 Ribosomal RNA large subunit methyltransferase E OS=Natronomonas moolapensis (strain DSM 18674 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 186.1 0.0 2.9e-58 8.7e-56 1 177 [] 16 190 .. 16 190 .. 0.99 Alignments for each domain: == domain 1 score: 186.1 bits; conditional E-value: 2.9e-58 TTSHHHHHHHHHHHHH--S-TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS-----TT-EEEE--TTSSSHHHHHHHHHHHSS CS FtsJ 1 yrsRsayKLleidekfklfkpgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpmaplpgvttiqgditdpetiekikealserk 87 yrsR+ayKL ++d+ +l++ g+tvvDlgaaPGgw qv+++ +g++g vv+vDlq ++ ++gv+ti+gd td+ t+e+i e ++e tr|M1XTZ7|M1XTZ7_NATM8 16 YRSRAAYKLKQLDSDAGLVSDGDTVVDLGAAPGGWLQVASELVGEGGTVVGVDLQRIDSIDGVETIRGDMTDEGTREQIVESVGE-- 100 9*******************************************************************************98866.. PP EEEEEE-------S-HHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEE-STTHHHHHHHHGGGEEEEEEE----------EEEEEE CS FtsJ 88 vdlvvsDgapdvsgvhdldeylqsqLllaalelalkllkpggtfvlkifrgeeteallkqlkkfFekvsvvkPkssrsesseeflvc 174 +d vvsD+ap+++g +ld+++++ L++ a+e+al+ll+pgg fv+k+f+g++t+al +++++ Fe+v+ + P +sr +sse ++v+ tr|M1XTZ7|M1XTZ7_NATM8 101 ADAVVSDMAPNMTGEYSLDHARSVYLARMAFETALELLAPGGDFVAKVFEGPDTDALRADIDEEFEYVRTIHPDASRDSSSELYMVA 187 *************************************************************************************** PP EEE CS FtsJ 175 rgf 177 +g+ tr|M1XTZ7|M1XTZ7_NATM8 188 KGR 190 985 PP >> tr|M1XPJ5|M1XPJ5_NATM8 tRNA/rRNA cytosine-C5-methylase OS=Natronomonas moolapensis (strain DSM 18674 / JCM 14361 / 8 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.8 0.0 9.7e-09 2.9e-06 21 147 .. 99 244 .. 88 251 .. 0.78 Alignments for each domain: == domain 1 score: 24.8 bits; conditional E-value: 9.7e-09 TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS--...---...TT-EEEE--TTSSSHHHHHHHHHHHSSEEEEEE-------S CS FtsJ 21 pgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm...apl...pgvttiqgditdpetiekikealserkvdlvvsDgapdvsg 101 pg++v+D++aaPG+ + l+ r+ +g +v+ D + + a++ +++ + + +t+ ++++ ++ ++++ +d + D+ +++g tr|M1XPJ5|M1XPJ5_NATM8 99 PGERVLDCCAAPGSKTTQLAARMDDRGLLVGNDNNLGrlsALRsnaERCGVTNLVVTRADARNFSLKSFGGEAFDRTLVDVPCSCEG 185 899********************999*******988877733332355555566678888888888899999999999999988888 PP -.HHHHHHHH..........HHHHHHHHHHHHHHEEEEEEEEEEEE-..STTHHHHHHH CS FtsJ 102 v.hdldeylq..........sqLllaalelalkllkpggtfvlkifr..geeteallkq 147 + ++ + +l+ + + l al++ +pggt+v +++ ee ea++++ tr|M1XPJ5|M1XPJ5_NATM8 186 TiRKNPDALEdwsmdhvegiAGVQKGILDRALEITRPGGTVVYSTCTfaPEENEAIVQH 244 6655555555588888888768899999999999********98888545555566666 PP >> tr|M1XS10|M1XS10_NATM8 Probable rRNA methyltransferase OS=Natronomonas moolapensis (strain DSM 18674 / JCM 14361 / 8 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.1 0.0 4.6e-06 0.0014 21 72 .. 54 115 .. 39 126 .. 0.84 Alignments for each domain: == domain 1 score: 16.1 bits; conditional E-value: 4.6e-06 TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS--............---TT-EEEE--TTS CS FtsJ 21 pgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm............aplpgvttiqgditd 72 +g+tv+Dlg+++G + ++ r g+ vv+vD+ p + v+ ++gd+td tr|M1XS10|M1XS10_NATM8 54 EGRTVLDLGCGTGMLALGAALR-GP-ELVVGVDIDPAplstarenerrvGAMTDVSWVRGDVTD 115 789*******************.87.99********9999888776555556888888**9998 PP >> tr|M1Y1P2|M1Y1P2_NATM8 Probable S-adenosylmethionine-dependent methyltransferase OS=Natronomonas moolapensis (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.2 0.0 3.6e-05 0.011 21 66 .. 36 86 .. 18 103 .. 0.78 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 3.6e-05 TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS--........---TT-EEE CS FtsJ 21 pgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm........aplpgvtti 66 p +t+ Dlg+++G +++ ++++ g v avD+q ++++v+t+ tr|M1Y1P2|M1Y1P2_NATM8 36 PAETIADLGSGTGFYTDLVARHA---GTVHAVDVQAAmheryvekGLPDNVQTV 86 66899***************994...78******88756655543233566665 PP >> tr|M1XL08|M1XL08_NATM8 Probable arsenite(III)-methyltransferase OS=Natronomonas moolapensis (strain DSM 18674 / JCM # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.0 0.0 4.3e-05 0.013 19 77 .. 93 162 .. 86 249 .. 0.72 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 4.3e-05 S-TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS--.........---...TT-EEEE--TTSSSHHH CS FtsJ 19 fkpgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm.........apl...pgvttiqgditdpetie 77 ++ g++v+Dlg++ G + ++q++g++g+v++vD+ p + ++v++ g i + + + tr|M1XL08|M1XL08_NATM8 93 LNAGEAVLDLGSGAGFDCFLAAQEVGETGRVIGVDMTPEmikkaranaS-QngaENVEFRLGEIEHLPVSD 162 678999**********9*********99********7655775544331.123345555555555444443 PP >> tr|M1XTN7|M1XTN7_NATM8 Probable S-adenosylmethionine-dependent methyltransferase OS=Natronomonas moolapensis (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.0 0.0 4.3e-05 0.013 20 54 .. 30 62 .. 15 94 .. 0.84 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 4.3e-05 -TT-EEEEES-TT-HHHHHHTTT...-SEEEEEES CS FtsJ 20 kpgktvvDlgaaPGgwsqvllqrlgakgkvvavDl 54 + ++vvD+g++ G+ + vl +++ + g vv++D tr|M1XTN7|M1XTN7_NATM8 30 DDCERVVDVGCGEGALTRVLREEC-P-GEVVGCDR 62 56789******************6.5.99****96 PP >> tr|M1XNA3|M1XNA3_NATM8 Probable demethylmenaquinone methyltransferase OS=Natronomonas moolapensis (strain DSM 18674 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 13.1 0.0 3.9e-05 0.012 12 73 .. 37 103 .. 34 165 .. 0.82 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 3.9e-05 HHHHH--S-TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS--.........---TT-EEEE--TTSS CS FtsJ 12 idekfklfkpgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm.........aplpgvttiqgditdp 73 ++e f+ ++ g++v+D+g+++G ++ ll+++ v ++D+ ++++v++++gd + tr|M1XNA3|M1XNA3_NATM8 37 ALEWFG-IEAGDRVLDVGCGTGFATEGLLEHT---DDVWGLDQSAHqlekafgkfGKRDRVNFHRGDAERL 103 566677.789*********************6...469****98886887776655679999999998654 PP >> tr|M1XP07|M1XP07_NATM8 Probable S-adenosylmethionine-dependent methyltransferase (Homolog to 24-sterol C-methyltrans # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 8.5 0.0 0.001 0.31 11 57 .. 29 73 .. 20 109 .. 0.76 2 ? 1.9 0.0 0.11 32 122 137 .. 127 142 .. 118 154 .. 0.80 Alignments for each domain: == domain 1 score: 8.5 bits; conditional E-value: 0.001 HHHHHH--S-TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS-- CS FtsJ 11 eidekfklfkpgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm 57 ++++++ ++ g+tv+Dlg++ G l + + a ++v+++D p tr|M1XP07|M1XP07_NATM8 29 HALARMP-VEAGETVLDLGCGSGYAGRALREATDA-ARVYGLDGAPE 73 5556666.77899**********999999999876.*******8654 PP == domain 2 score: 1.9 bits; conditional E-value: 0.11 HHHEEEEEEEEEEEE- CS FtsJ 122 lkllkpggtfvlkifr 137 ++l+pggtf + + tr|M1XP07|M1XP07_NATM8 127 RRVLRPGGTFYCAVNY 142 489********98755 PP >> tr|M1Y4D2|M1Y4D2_NATM8 Probable S-adenosylmethionine-dependent methyltransferase OS=Natronomonas moolapensis (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 7.8e-05 0.024 21 70 .. 44 102 .. 21 129 .. 0.80 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 7.8e-05 TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS--...........---.TT-EEEE--T CS FtsJ 21 pgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm...........apl.pgvttiqgdi 70 ++k+++++++++G ++ +l+ r g + +v++D+ + a + + +++iqgd tr|M1Y4D2|M1Y4D2_NATM8 44 EDKRILEVACGTGRFTVMLADR-G--ADIVGMDISEAmleqgrrkarsAGVdESLSFIQGDA 102 56889*****************.6..69******6665998887544333367888889987 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (177 nodes) Target sequences: 2723 (809592 residues searched) Passed MSV filter: 64 (0.0235035); expected 54.5 (0.02) Passed bias filter: 63 (0.0231362); expected 54.5 (0.02) Passed Vit filter: 13 (0.00477415); expected 2.7 (0.001) Passed Fwd filter: 9 (0.00330518); expected 0.0 (1e-05) Initial search space (Z): 2723 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.03u 0.00s 00:00:00.03 Elapsed: 00:00:00.02 # Mc/sec: 7164.89 // [ok]