# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/FtsJ.hmm.txt
# target sequence database: proteomes/Saccharomyces_cerevisiae.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: FtsJ [M=177]
Accession: PF01728.18
Description: FtsJ-like methyltransferase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
5.9e-67 223.7 0.0 7.5e-67 223.3 0.0 1.1 1 sp|P38238|TRM7_YEAST tRNA (cytidine(32)/guanosine(34)-2'-O)-
2.8e-55 185.6 0.1 6.4e-55 184.5 0.1 1.7 1 sp|P25582|SPB1_YEAST 27S pre-rRNA (guanosine(2922)-2'-O)-met
3e-50 169.3 0.0 4.5e-50 168.7 0.0 1.3 1 sp|P53123|MRM2_YEAST rRNA methyltransferase 2, mitochondrial
0.00077 18.1 0.0 0.0016 17.1 0.0 1.5 1 sp|P38205|NCL1_YEAST Multisite-specific tRNA:(cytosine-C(5))
0.0018 16.9 0.0 0.0045 15.6 0.0 1.6 2 sp|P38074|HMT1_YEAST Protein arginine N-methyltransferase 1
0.0036 15.9 0.0 0.0046 15.5 0.0 1.2 1 sp|P15646|FBRL_YEAST rRNA 2'-O-methyltransferase fibrillarin
0.0072 14.9 0.0 0.019 13.5 0.0 1.7 1 sp|P40991|NOP2_YEAST 25S rRNA (cytosine(2870)-C(5))-methyltr
Domain annotation for each sequence (and alignments):
>> sp|P38238|TRM7_YEAST tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase OS=Saccharomyces cerevisiae (strain AT
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 223.3 0.0 8.7e-70 7.5e-67 1 177 [] 21 207 .. 21 207 .. 0.96
Alignments for each domain:
== domain 1 score: 223.3 bits; conditional E-value: 8.7e-70
TTSHHHHHHHHHHHHH--S-..TT-EEEEES-TT-HHHHHHTTT...........-SEEEEEESS-----TT-EEEE--TTSSSHHHHH CS
FtsJ 1 yrsRsayKLleidekfklfk..pgktvvDlgaaPGgwsqvllqrl........gakgkvvavDlqpmaplpgvttiqgditdpetieki 79
yr+Rsa+KLl+++++f++++ + k+vvDl+aaPG+wsqvl+++l +++ k+v+vDlqpm+p+p+vtt+q+dit+p+t +i
sp|P38238|TRM7_YEAST 21 YRARSAFKLLQLNDQFHFLDdpNLKRVVDLCAAPGSWSQVLSRKLfdespssdKEDRKIVSVDLQPMSPIPHVTTLQADITHPKTLARI 109
9****************997778899*******************888777653359******************************** PP
HHHHHHSSEEEEEE-------S-HHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEE-STTHHHHHHHHGGGEEEEEEE---------- CS
FtsJ 80 kealserkvdlvvsDgapdvsgvhdldeylqsqLllaalelalkllkpggtfvlkifrgeeteallkqlkkfFekvsvvkPkssrsess 168
+++++++k+d+v+sDgapdv+g hdldey+q qL+++al+l+ +lk+ggtfv+kifrg++++ l++ql +F+k+ ++kP+ssr +s
sp|P38238|TRM7_YEAST 110 LKLFGNEKADFVCSDGAPDVTGLHDLDEYVQQQLIMSALQLTACILKKGGTFVAKIFRGRDIDMLYSQLGYLFDKIVCAKPRSSRGTSL 198
***************************************************************************************** PP
EEEEEEEEE CS
FtsJ 169 eeflvcrgf 177
e+f+vc+g+
sp|P38238|TRM7_YEAST 199 EAFIVCLGY 207
******986 PP
>> sp|P25582|SPB1_YEAST 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 184.5 0.1 7.4e-58 6.4e-55 1 177 [] 25 202 .. 25 202 .. 0.98
Alignments for each domain:
== domain 1 score: 184.5 bits; conditional E-value: 7.4e-58
TTSHHHHHHHHHHHHH--S.-TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS-----TT-EEEE--TTSSSHHHHHHHHHHHSSE CS
FtsJ 1 yrsRsayKLleidekfklf.kpgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpmaplpgvttiqgditdpetiekikealserkv 88
yr+Rs++K+++i+ek++ f ++ k v+Dl+aaPG+w+qv+++ + ++ +++vD+ pm+p+p+v t+q dit+++ + k++ +++ k+
sp|P25582|SPB1_YEAST 25 YRARSSFKIIQINEKYGHFlEKSKVVIDLCAAPGSWCQVASKLCPVNSLIIGVDIVPMKPMPNVITFQSDITTEDCRSKLRGYMKTWKA 113
9***************97736999*******************9889****************************************** PP
EEEEE-------S-HHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEE-STTHHHHHHHHGGGEEEEEEE----------EEEEEEEEE CS
FtsJ 89 dlvvsDgapdvsgvhdldeylqsqLllaalelalkllkpggtfvlkifrgeeteallkqlkkfFekvsvvkPkssrsesseeflvcrgf 177
d v++Dgap+v + +++d+++qsqL l+al+la++ l +gtfv+kifr+++ ++l+ ++++Fekv+ +kP++sr+ s+e+f+vc+gf
sp|P25582|SPB1_YEAST 114 DTVLHDGAPNVGLGWVQDAFTQSQLTLQALKLAVENLVVNGTFVTKIFRSKDYNKLIWVFQQLFEKVEATKPPASRNVSAEIFVVCKGF 202
***************************************************************************************98 PP
>> sp|P53123|MRM2_YEAST rRNA methyltransferase 2, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 168.7 0.0 5.2e-53 4.5e-50 2 176 .. 50 306 .. 49 307 .. 0.97
Alignments for each domain:
== domain 1 score: 168.7 bits; conditional E-value: 5.2e-53
TSHHHHHHHHHHHHH--S-TT-E...EEEES-TT-HHHHHHTTT...-SEEEEEESS-----TT-EEEE--TTSSSHHHHHHHHHHH.. CS
FtsJ 2 rsRsayKLleidekfklfkpgkt...vvDlgaaPGgwsqvllqrlgakgkvvavDlqpmaplpgvttiqgditdpetiekikealse.. 85
rsR+a+KL++id+k++lf++++t ++Dlg+aPG+wsqv+ qr +++++++vD+ p++p+ gv++iq++i+ ++t+++i+ ++s+
sp|P53123|MRM2_YEAST 50 RSRAAFKLMQIDDKYRLFSKNRTdqrILDLGYAPGAWSQVARQRSSPNSMILGVDILPCEPPHGVNSIQANILAKRTHDLIRLFFSKhf 138
9*****************85544444******************9889**********************************9999999 PP
........................................................SSEEEEEE----..................... CS
FtsJ 86 ........................................................rkvdlvvsDgap..................... 97
+vd+++sD+ +
sp|P53123|MRM2_YEAST 139 qlnrhddlhkdhgyfqnmleeelthvkdtelyreiftsddiyetpntnstlierekFPVDVIISDMYEpwpqttgfwnnitnqayfrma 227
9****************************************************99999*********88******************** PP
---S-HHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEE-STTHHHHHHHHGGGEEEEEEE----------EEEEEEEE CS
FtsJ 98 dvsgvhdldeylqsqLllaalelalkllkpggtfvlkifrgeeteallkqlkkfFekvsvvkPkssrsesseeflvcrg 176
++sgv+ d+y++++L++aal +a++ll+p g+fv+k+++gee + + k+++++F +v+ +kP +sr es+e++++ ++
sp|P53123|MRM2_YEAST 228 NTSGVSIRDHYQSIDLCDAALVTAIDLLRPLGSFVCKLYTGEEENLFKKRMQAVFTNVHKFKPDASRDESKETYYIGLK 306
***************************************************************************9876 PP
>> sp|P38205|NCL1_YEAST Multisite-specific tRNA:(cytosine-C(5))-methyltransferase OS=Saccharomyces cerevisiae (strain A
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 17.1 0.0 1.8e-06 0.0016 19 137 .. 163 311 .. 146 338 .. 0.61
Alignments for each domain:
== domain 1 score: 17.1 bits; conditional E-value: 1.8e-06
S-TT-EEEEES-TT-HHHHHHTTT........-SEEEEEESS--.........---..TT-EEEE--TTSSSHHHHHHHHHHH...... CS
FtsJ 19 fkpgktvvDlgaaPGgwsqvllqrlga.....kgkvvavDlqpm.........apl..pgvttiqgditdpetiekikealse...... 85
+kp +tv+D +aaPG+ + l + l++ +g vva D + l ++ +++ d + i++ +
sp|P38205|NCL1_YEAST 163 VKPHHTVLDMCAAPGSKTAQLIEALHKdtdepSGFVVANDADARrshmlvhqlKRLnsANLMVVNHDAQFFPRIRLH-----Gnsnnkn 246
4689*********************6655544699*****9887444444332222222333334444444444333.....1334446 PP
..SSEEEEEE----..........---S-HHHHHHHH...........H.HHHHHHHHHHHHHEEEEEEEEEEEE- CS
FtsJ 86 ..rkvdlvvsDgap..........dvsgvhdldeylq...........s.qLllaalelalkllkpggtfvlkifr 137
k+d +++D+ + + l+ l+ +l+llk++g +v ++
sp|P38205|NCL1_YEAST 247 dvLKFDRILCDVPCsgdgtmrknvN-----------VwkdwntqaglgLhAVQLNILNRGLHLLKNNGRLVYSTCS 311
6678999999986334443333222...........1223444433222244444445577778888877766655 PP
>> sp|P38074|HMT1_YEAST Protein arginine N-methyltransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 15.6 0.0 5.2e-06 0.0045 14 60 .. 52 95 .. 31 132 .. 0.82
2 ? -2.2 0.0 1.5 1.3e+03 47 75 .. 187 219 .. 176 246 .. 0.63
Alignments for each domain:
== domain 1 score: 15.6 bits; conditional E-value: 5.2e-06
HHH--S-TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS----- CS
FtsJ 14 ekfklfkpgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpmapl 60
+ +lf ++k v+D+g+++G s +++++ ga ++v++vD+ ++ +
sp|P38074|HMT1_YEAST 52 QNKDLF-KDKIVLDVGCGTGILSMFAAKH-GA-KHVIGVDMSSIIEM 95
444556.6789******************.88.99******998444 PP
== domain 2 score: -2.2 bits; conditional E-value: 1.5
SEEEEEESS-----....TT-EEE.E--TTSSSH CS
FtsJ 47 gkvvavDlqpmapl....pgvtti.qgditdpet 75
+ v+++D p pl p v t+ + ++++
sp|P38074|HMT1_YEAST 187 QDVYGFDYSPFVPLvlhePIVDTVeRNNVNTT-S 219
56888888888666566677777743333332.2 PP
>> sp|P15646|FBRL_YEAST rRNA 2'-O-methyltransferase fibrillarin OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 15.5 0.0 5.3e-06 0.0046 16 97 .. 162 246 .. 147 286 .. 0.86
Alignments for each domain:
== domain 1 score: 15.5 bits; conditional E-value: 5.3e-06
H--S-TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS--.........---TT-EEEE--TTSSSHHHHHHHHHHHSSEEEEEE-- CS
FtsJ 16 fklfkpgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm.........aplpgvttiqgditdpetiekikealserkvdlvvsDg 95
+ pgk+v+ lgaa G ++ +g++g+v+av + +++p++ i d ++p++ +++ vd+v +D+
sp|P15646|FBRL_YEAST 162 LF-IAPGKKVLYLGAASGTSVSHVSDVVGPEGVVYAVEFSHRpgrelismaKKRPNIIPIIEDARHPQKYRMLIG-----MVDCVFADV 244
33.579*********************************888889998886677999999***********9996.....59******9 PP
-- CS
FtsJ 96 ap 97
a
sp|P15646|FBRL_YEAST 245 AQ 246
93 PP
>> sp|P40991|NOP2_YEAST 25S rRNA (cytosine(2870)-C(5))-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 20450
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 13.5 0.0 2.2e-05 0.019 21 137 .. 345 479 .. 325 496 .. 0.59
Alignments for each domain:
== domain 1 score: 13.5 bits; conditional E-value: 2.2e-05
TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS--...---TT-EEE...E--TTSSSHHHHHHHHHHHSSEEEEEE-------S-H CS
FtsJ 21 pgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm...aplpgvtti...qgditdpetiekikealserkvdlvvsDgapdvsgvh 103
++++++D +aaPGg + +++ ++++g v+a D ++ +++ +++ + ++ + + +++ ++ + +++ +d ++ D + +gv
sp|P40991|NOP2_YEAST 345 ENERILDMAAAPGGKTTYISAMMKNTGCVFANDANKSrtkSLIANIHRLgctNTIVCNYDAR-EFPKVIGG--FDRILLDAPCSGTGVI 430
6788*******************99999******9985542334444444212222222222.23333333..5555555443333333 PP
HHHHHHH...............HHHHHHHHHHHHHHEEEEEEEEEEEE- CS
FtsJ 104 dldeylq...............sqLllaalelalkllkpggtfvlkifr 137
+d+ ++ qLll+a+ k+gg++v ++
sp|P40991|NOP2_YEAST 431 GKDQSVKvsrtekdfiqiphlqKQLLLSAIDSVDCNSKHGGVIVYSTCS 479
3333333333333333344454577777777766777777777765555 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (177 nodes)
Target sequences: 6049 (2936363 residues searched)
Passed MSV filter: 198 (0.0327327); expected 121.0 (0.02)
Passed bias filter: 169 (0.0279385); expected 121.0 (0.02)
Passed Vit filter: 20 (0.00330633); expected 6.0 (0.001)
Passed Fwd filter: 7 (0.00115722); expected 0.1 (1e-05)
Initial search space (Z): 6049 [actual number of targets]
Domain search space (domZ): 7 [number of targets reported over threshold]
# CPU time: 0.05u 0.00s 00:00:00.05 Elapsed: 00:00:00.02
# Mc/sec: 25986.81
//
[ok]