# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/FtsJ.hmm.txt
# target sequence database:        proteomes/Trypanosoma_brucei.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       FtsJ  [M=177]
Accession:   PF01728.18
Description: FtsJ-like methyltransferase
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    6.8e-65  217.4   0.0    1.1e-64  216.7   0.0    1.3  1  tr|Q586L7|Q586L7_TRYB2  Putative tRNA (cytidine(32)/guanosine
    1.3e-54  183.9   0.0      2e-54  183.3   0.0    1.3  1  tr|Q586Q7|Q586Q7_TRYB2  Putative rRNA methyltransferase OS=Tr
    4.1e-46  156.2   0.1    4.8e-46  156.0   0.1    1.0  1  tr|Q57XD9|Q57XD9_TRYB2  Ribosomal RNA methyltransferase, puta
    4.9e-44  149.5   0.1    5.8e-44  149.3   0.1    1.1  1  tr|Q57Y21|Q57Y21_TRYB2  rRNA methyltransferase, putative OS=T
    2.1e-32  111.6   0.0      4e-32  110.7   0.0    1.4  2  sp|Q38AH0|MTR1_TRYB2    Cap-specific mRNA (nucleoside-2'-O-)-
      2e-05   23.8   0.1    4.8e-05   22.5   0.0    1.7  2  tr|Q583H8|Q583H8_TRYB2  Nucleolar protein, putative OS=Trypan
    9.7e-05   21.5   0.0    0.00026   20.1   0.1    1.8  2  tr|Q57V63|Q57V63_TRYB2  Uncharacterized protein OS=Trypanosom
    0.00028   20.0   0.0     0.0005   19.2   0.0    1.3  1  tr|Q38AT8|Q38AT8_TRYB2  Uncharacterized protein OS=Trypanosom
     0.0005   19.2   0.0      0.001   18.2   0.0    1.4  1  tr|Q388U8|Q388U8_TRYB2  Methyltransferase, putative OS=Trypan
     0.0012   17.9   0.0     0.0034   16.5   0.0    1.6  1  tr|Q38FU9|Q38FU9_TRYB2  Uncharacterized protein OS=Trypanosom
     0.0021   17.2   0.0     0.0029   16.7   0.0    1.3  1  tr|Q4GYA9|Q4GYA9_TRYB2  Arginine N-methyltransferase, putativ
     0.0082   15.2   0.4       0.06   12.4   0.4    2.1  1  tr|Q580I8|Q580I8_TRYB2  Uncharacterized protein OS=Trypanosom
  ------ inclusion threshold ------
      0.014   14.4   0.0      0.023   13.8   0.0    1.3  1  tr|Q388E0|Q388E0_TRYB2  Fibrillarin, putative OS=Trypanosoma 
      0.018   14.1   0.0       0.12   11.4   0.0    2.2  2  tr|Q582C3|Q582C3_TRYB2  Uncharacterized protein OS=Trypanosom
      0.028   13.5   0.0       0.04   13.0   0.0    1.3  1  tr|Q388C9|Q388C9_TRYB2  Fibrillarin, putative OS=Trypanosoma 


Domain annotation for each sequence (and alignments):
>> tr|Q586L7|Q586L7_TRYB2  Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase OS=Trypanosoma brucei bruce
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  216.7   0.0     2e-67   1.1e-64       1     177 []      21     310 ..      21     310 .. 0.96

  Alignments for each domain:
  == domain 1  score: 216.7 bits;  conditional E-value: 2e-67
                             TTSHHHHHHHHHHHHH--S-TT-E...EEEES-TT-HHHHHHTTT.........................-SEEEEEESS-----TT CS
                    FtsJ   1 yrsRsayKLleidekfklfkpgkt...vvDlgaaPGgwsqvllqrl......................gakgkvvavDlqpmaplpg 62 
                             yr+RsayKLl+++e+f+++++++    vvDl+aaPG+wsqvl+++l                       +++++vavDlq+m p++g
  tr|Q586L7|Q586L7_TRYB2  21 YRARSAYKLLQLHEEFGILRREEIrtgVVDLCAAPGSWSQVLSNHLcgsqpgsaaeacegdeainseaSQRPRIVAVDLQEMMPIDG 107
                             9******************85533447*******************9999999999988887776644226**************** PP

                             -EEEE--TTSSSHHHHHHHHHHH................................................................ CS
                    FtsJ  63 vttiqgditdpetiekikealse................................................................ 85 
                             v+++qgdit++ t+++i ++l++                                                                
  tr|Q586L7|Q586L7_TRYB2 108 VQLLQGDITSEWTAREIIRLLNGdsssvpecsdatalstagaindfnngrgnnvseegkssqqrsdcgvglmnernnasecvdgdnn 194
                             **********************9**************************************************************** PP

                             ........................SSEEEEEE-------S-HHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEE-STTHHHHHHHH CS
                    FtsJ  86 ........................rkvdlvvsDgapdvsgvhdldeylqsqLllaalelalkllkpggtfvlkifrgeeteallkql 148
                                                     rk+dlvv+Dgapdv+g+h+ldeylq +Lllaal++++ +l++ggtfv+k+frg++t +l+++ 
  tr|Q586L7|Q586L7_TRYB2 195 nnnsnnnddrnggdagastrpvagRKADLVVCDGAPDVTGMHELDEYLQHHLLLAALNITTFVLRRGGTFVTKMFRGPNTPFLVAKA 281
                             *************************************************************************************** PP

                             GGGEEEEEEE----------EEEEEEEEE CS
                    FtsJ 149 kkfFekvsvvkPkssrsesseeflvcrgf 177
                             + fF++v+++kPkssr++s e+f+vc+++
  tr|Q586L7|Q586L7_TRYB2 282 EVFFRQVTIAKPKSSRNASMEAFMVCQNY 310
                             **************************996 PP

>> tr|Q586Q7|Q586Q7_TRYB2  Putative rRNA methyltransferase OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=1854
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  183.3   0.0   3.6e-57     2e-54       1     177 []      25     201 ..      25     201 .. 0.99

  Alignments for each domain:
  == domain 1  score: 183.3 bits;  conditional E-value: 3.6e-57
                             TTSHHHHHHHHHHHHH--S-TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS-----TT-EEEE--TTSSSHHHHHHHHHHHSS CS
                    FtsJ   1 yrsRsayKLleidekfklfkpgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpmaplpgvttiqgditdpetiekikealserk 87 
                             +r+Rsa+KL +++ k++++++ +  vDl+aaPG+w+qv+++++  ++k+v+vDl p+ap+ gv+t+ gdit+++t++ i ++l++++
  tr|Q586Q7|Q586Q7_TRYB2  25 FRARSAFKLVQLNRKYDFLSKCRVLVDLCAAPGSWCQVAAKHMPVGSKIVGVDLVPIAPIRGVKTFVGDITEEKTKKIIMTYLKREP 111
                             79***************99************************999***************************************** PP

                             EEEEEE-------S-HHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEE-STTHHHHHHHHGGGEEEEEEE----------EEEEEE CS
                    FtsJ  88 vdlvvsDgapdvsgvhdldeylqsqLllaalelalkllkpggtfvlkifrgeeteallkqlkkfFekvsvvkPkssrsesseeflvc 174
                             vd+v++Dgap+v gv++ d + q +L+l a +la+kll+pgg fv+k+fr++++ +l+  +k++F+kv+ +kP +sr es+e+f+ c
  tr|Q586Q7|Q586Q7_TRYB2 112 VDCVIHDGAPNVGGVWSRDLFEQNSLVLHAAKLASKLLRPGGWFVTKVFRSQDFHKLMWVMKQLFDKVEATKPLASRMESAEIFVTC 198
                             *************************************************************************************** PP

                             EEE CS
                    FtsJ 175 rgf 177
                              g+
  tr|Q586Q7|Q586Q7_TRYB2 199 AGY 201
                             986 PP

>> tr|Q57XD9|Q57XD9_TRYB2  Ribosomal RNA methyltransferase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  156.0   0.1   8.4e-49   4.8e-46       1     177 []      34     218 ..      34     218 .. 0.92

  Alignments for each domain:
  == domain 1  score: 156.0 bits;  conditional E-value: 8.4e-49
                             TTSHHHHHHHHHHHHH--S-..TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS-----.TT-EEEE--TTSSSHHHHHHHHHH CS
                    FtsJ   1 yrsRsayKLleidekfklfk..pgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpmapl.pgvttiqgditdpetiekikeals 84 
                             y++Rsa+KLle+d+kf lf+  +++ vvD+g++PG+w qv+ +r+g k+ v++vD+  +a    g  +iqgd+t+p+++e+++  + 
  tr|Q57XD9|Q57XD9_TRYB2  34 YVARSAFKLLEMDDKFTLFSrgNTRVVVDIGCSPGSWLQVIRERCGDKCAVFGVDVLRVASTvTGAVCIQGDFTNPAVREELLARMV 120
                             99*****************8455566******************************9996666*****************9998777 PP

                             H....SSEEEEEE-------S-HHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEE-STTHH.HHHHHHGGGEEEEEEE-------- CS
                    FtsJ  85 e....rkvdlvvsDgapdvsgvhdldeylqsqLllaalelalkllkpggtfvlkifrgeete.allkqlkkfFekvsvvkPkssrse 166
                                    vd+v+sD++ +    ++ d  +q +L ++al +al++l pgg+fv+k++ ++ +  +l +++ + F + +++kP+ssr +
  tr|Q57XD9|Q57XD9_TRYB2 121 TvraaGVVDVVTSDMCLNRGTGSTSDRQKQEELNRSALAFALEQLVPGGNFVCKVLGSPTAYeELRRDTCRWFVRTDICKPSSSRLT 207
                             7666667*********988888***********************************77777488888999**************** PP

                             --EEEEEEEEE CS
                    FtsJ 167 sseeflvcrgf 177
                             s e+f+vcrg+
  tr|Q57XD9|Q57XD9_TRYB2 208 SDEAFMVCRGK 218
                             *********85 PP

>> tr|Q57Y21|Q57Y21_TRYB2  rRNA methyltransferase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  149.3   0.1     1e-46   5.8e-44       1     177 []       2     225 ..       2     225 .. 0.85

  Alignments for each domain:
  == domain 1  score: 149.3 bits;  conditional E-value: 1e-46
                             TTSHHHHHHHHHHHHH--S-.TT-EEEEES-TT-HHHHHHTTT.............-SEEEEEESS-----TT-EEEE--T.TSSSH CS
                    FtsJ   1 yrsRsayKLleidekfklfk.pgktvvDlgaaPGgwsqvllqrlga..........kgkvvavDlqpmaplpgvttiqgdi.tdpet 75 
                             yr+RsayKLle+d+kf+lf    +tvvDl+aaPGg+s+v+lqr++a          k+ v+a+D++pm+    ++++q++i  ++++
  tr|Q57Y21|Q57Y21_TRYB2   2 YRCRSAYKLLELDDKFSLFGgCCRTVVDLAAAPGGFSEVALQRMTAaedvtsrppvKPLVIAFDTRPMKAARDLHVVQCNInDHKRV 88 
                             9******************8899*********************5555555555557************************556778 PP

                             HHHHHHHHHH........SSEEEEEE-------S-HHHHHHHH..HHHHHHHHHHHHHHEE.......................... CS
                    FtsJ  76 iekikealse........rkvdlvvsDgapdvsgvhdldeylq..sqLllaalelalkllk.......................... 126
                             i  ++e++++        r+vd+v++Dg+ +v   h+  +++    q++  al+la++l+                           
  tr|Q57Y21|Q57Y21_TRYB2  89 IASVEEFIQRrgvgdgadRQVDVVLHDGV-SVAKSHSAFSVTYaqNQMAVGALRLACALFLlssqpagtrqppraedglassskaep 174
                             88999988889******************.665556555554433466666666666554445566668888888888889999998 PP

                             EEEEEEEEEE-STTHHHHHHHHGGGEEEEEEE----------EEEEEEEEE CS
                    FtsJ 127 pggtfvlkifrgeeteallkqlkkfFekvsvvkPkssrsesseeflvcrgf 177
                             +g tfv+k++r+++++++l+++k++F++vsv++P++++ +sse+++v+rgf
  tr|Q57Y21|Q57Y21_TRYB2 175 QGPTFVTKAMRSAHFNQVLSAMKAYFRHVSVHRPAECNAASSETYVVARGF 225
                             999**********************************************98 PP

>> sp|Q38AH0|MTR1_TRYB2  Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 OS=Trypanosoma brucei brucei (strain 9
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  110.7   0.0     7e-35     4e-32       1     177 []      88     293 ..      88     293 .. 0.88
   2 ?   -3.6   0.0       8.6   4.9e+03      48      61 ..     331     347 ..     322     366 .. 0.63

  Alignments for each domain:
  == domain 1  score: 110.7 bits;  conditional E-value: 7e-35
                           TTSHHHHHHHHHHHHH--S-..TT-E........EEEES-TT-HHHHHHTTT.......-SEEEEEESS--......---TT-EEE... CS
                  FtsJ   1 yrsRsayKLleidekfklfk..pgkt........vvDlgaaPGgwsqvllqrlga....kgkvvavDlqpm......aplpgvtti... 66 
                           +r+R+++KL e  e+++l +  +g++        +vD++ +PG++sq l    g+    + + ++++l+++      + lp  +++   
  sp|Q38AH0|MTR1_TRYB2  88 FRNRAGHKLHETMEAVGLWEylKGGAtrakgtftFVDVCGGPGAFSQALFAM-GKehklRLRGFGLTLRNVkgldwyTDLPSRSFFpcy 175
                           79***************88766554457788888***************887.4435445999*****999666666455666666889 PP

                           ....E--TTSSSHHHHHHHHHHHSSEEEEEE------.-S-HHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEE-.STTHH.HHHHHH CS
                  FtsJ  67 ....qgditdpetiekikealserkvdlvvsDgapdv.sgvhdldeylqsqLllaalelalkllkpggtfvlkifr.geete.allkql 148
                               +gd+++ e+ie +  ++ ++ v lvv+Dg++dv + v +++e+++++++  ++  a+kll+pgg+fvlk+f+ ++ ++ a+l  +
  sp|Q38AH0|MTR1_TRYB2 176 gidgTGDVFKLENIESLCSLTCKENVRLVVADGGFDVpTEVVNFQETISCRIVYGQWLSAVKLLRPGGCFVLKLFDcFSPFTrAILFLT 264
                           99***********************************56669**********************************9777775888889 PP

                           GGGEEEEEEE----------EEEEEEEEE CS
                  FtsJ 149 kkfFekvsvvkPkssrsesseeflvcrgf 177
                            +++e+v+vvkP++sr  +se++lvc gf
  sp|Q38AH0|MTR1_TRYB2 265 THLYESVQVVKPRHSRVVNSERYLVCIGF 293
                           9*************************987 PP

  == domain 2  score: -3.6 bits;  conditional E-value: 8.6
                           EEEEEESS-----...T CS
                  FtsJ  48 kvvavDlqpmapl...p 61 
                           k+++ D+  m+     +
  sp|Q38AH0|MTR1_TRYB2 331 KIFGADVERMSATiasN 347
                           67788887773322333 PP

>> tr|Q583H8|Q583H8_TRYB2  Nucleolar protein, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 G
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.5   0.0   8.4e-08   4.8e-05      23     137 ..     258     386 ..     217     406 .. 0.72
   2 ?   -3.2   0.0       6.7   3.8e+03     124     147 ..     441     470 ..     429     492 .. 0.61

  Alignments for each domain:
  == domain 1  score: 22.5 bits;  conditional E-value: 8.4e-08
                             -EEEEES-TT-HHHHHHTTT...-SEEEEEESS-----TT-EEEE--TTSSSHHHHHHHHHHH.......SSEEEEEE----..... CS
                    FtsJ  23 ktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpmaplpgvttiqgditdpetiekikealse.......rkvdlvvsDgap..... 97 
                             ++v+D +aaPGg + +++q ++++g+++a D+ +    p+ ++++++ ++  + +++ +  ++       + +d ++ D        
  tr|Q583H8|Q583H8_TRYB2 258 ERVLDMAAAPGGKTTYIAQLMKNTGVIFANDVSE----PRTKSLNANLQRLGVTNTVVTNYDGvgfekvmKNFDRILLDAPCtgsgi 340
                             67*******************999********88....6666666666666666666655544555556655666666654323333 PP

                             .......---S-HHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEE- CS
                    FtsJ  98 .......dvsgvhdldeylqsqLllaalelalkllkpggtfvlkifr 137
                                    ++s  +  d  ++sqL ++ l  a++ ++ gg +v  ++ 
  tr|Q583H8|Q583H8_TRYB2 341 isrdksiKTSK-QYEDVQRASQLQRSLLLSAIDAVRVGGYIVYSTCS 386
                             33332103333.445555559******************99977665 PP

  == domain 2  score: -3.2 bits;  conditional E-value: 6.7
                             HEEEEEEEEEEEE-......STTHHHHHHH CS
                    FtsJ 124 llkpggtfvlkifr......geeteallkq 147
                             + + +g fv+k+ +      g++t++l k+
  tr|Q583H8|Q583H8_TRYB2 441 VHNMDGFFVCKLKKlsnnagGPSTNGLKKE 470
                             555677888887776666655555555554 PP

>> tr|Q57V63|Q57V63_TRYB2  Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.0       9.2   5.2e+03      97     120 ..      68      91 ..      66      98 .. 0.81
   2 !   20.1   0.1   4.5e-07   0.00026      20     137 ..     151     289 ..     119     316 .. 0.66

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 9.2
                             ----S-HHHHHHHHHHHHHHHHHH CS
                    FtsJ  97 pdvsgvhdldeylqsqLllaalel 120
                             p+v   +++ ey++s+Ll aal +
  tr|Q57V63|Q57V63_TRYB2  68 PSVPCATAVSEYVRSRLLHAALPV 91 
                             56666788999999****999976 PP

  == domain 2  score: 20.1 bits;  conditional E-value: 4.5e-07
                             -TT-EEEEES-TT-HHHHHHTTT......-SEEEEEESS--...........---TT-EEE..E--TTSSSHHHHHHHHHHHSSEEE CS
                    FtsJ  20 kpgktvvDlgaaPGgwsqvllqrl...gakgkvvavDlqpm...........aplpgvtti..qgditdpetiekikealserkvdl 90 
                              pg++v+D +aaPG+ +  +l+ +   +++g+vva Dl+             +p  + ++i  + d t+    +  k    e k+d 
  tr|Q57V63|Q57V63_TRYB2 151 APGNRVLDMCAAPGSKTSQILEAVissNQDGVVVANDLNVArldvllhqtarSPGAHPHLIvtNYDGTQFPLLP--K----EDKFDR 231
                             47899***************9999655446********988777776665432222333331133333333333..2....3689** PP

                             EEE-------S-HHHHHHHH..........HHHHHHHHHH...HHHHEEEEEEEEEEEE- CS
                    FtsJ  91 vvsDgapdvsgvhdldeylq..........sqLllaalel...alkllkpggtfvlkifr 137
                             v++D+   +sg  +l + +           ++L   ++++   ++ l+k+gg++v  ++ 
  tr|Q57V63|Q57V63_TRYB2 232 VLCDVM--CSGDGTLRKSMDmwprwntvhgADLHVTQVRVltrGMMLCKKGGIVVYSTCS 289
                             ****98..6776666666666666777777666666666622233577788887776666 PP

>> tr|Q38AT8|Q38AT8_TRYB2  Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   19.2   0.0   8.7e-07    0.0005      20     139 ..     168     345 ..     154     366 .. 0.81

  Alignments for each domain:
  == domain 1  score: 19.2 bits;  conditional E-value: 8.7e-07
                             -TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS--.---...TT-EEEE--TTSSSHHHHHHHHHHH................. CS
                    FtsJ  20 kpgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm.apl...pgvttiqgditdpetiekikealse................. 85 
                             +p+++++D +a+PG+ +  +l  lg  +kvv  D      p+   +   ++  di ++++  ++ + +++                 
  tr|Q38AT8|Q38AT8_TRYB2 168 QPTDKCLDMCASPGSKTAQILVSLGR-HKVVPHDSDASpFPFdydSEGLVVANDIDTKRANMLVHQ-VKRmrllfpfalftnhdaqf 252
                             58899***************999997.99*****98876555543444455899988888887774.56678999999999999*** PP

                             ............................SSEEEEEE-------S-.HHHHHHHH.......HHHHHHHHHH...HHHHEEEEEEEEE CS
                    FtsJ  86 ............................rkvdlvvsDgapdvsgv.hdldeylq.......sqLllaalel...alkllkpggtfvl 133
                                                          ++d +++D++ +  g+ ++ +++l+       ++L + ++++   a++ll+ gg +v 
  tr|Q38AT8|Q38AT8_TRYB2 253 fpnmvltpgeaqphtcgqqttgddgateLRFDKILCDVVCSGDGTiRKAPHILKmwspreaISLQKVQIQIalrACHLLRVGGRLVY 339
                             **************************9999********96666666777777779999999788888888844455799*****998 PP

                             EEE-ST CS
                    FtsJ 134 kifrge 139
                              ++   
  tr|Q38AT8|Q38AT8_TRYB2 340 STCSMN 345
                             877743 PP

>> tr|Q388U8|Q388U8_TRYB2  Methyltransferase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 G
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.2   0.0   1.8e-06     0.001      19     137 ..     262     416 ..     242     441 .. 0.67

  Alignments for each domain:
  == domain 1  score: 18.2 bits;  conditional E-value: 1.8e-06
                             S-TT-EEEEES-TT-HHHHHHTTT....................-SEEEEEESS--...---..TT-EEEE--T....TSSSHHHHH CS
                    FtsJ  19 fkpgktvvDlgaaPGgwsqvllqrl.................gakgkvvavDlqpm...apl..pgvttiqgdi....tdpetieki 79 
                             ++p +tv+D +aaPG+ +  +l ++                 ++k +v a  + p    +    p+v + ++d     +      + 
  tr|Q388U8|Q388U8_TRYB2 262 IQPHHTVLDMCAAPGSKTLQALDEMlkngwnssavssgvmvaNEKDRVKATQTLPArlkR-YhaPNVICTRCDAvqwpRLLCPTTQG 347
                             46889***********99999888888888777777766665336888888888885532.25799999999985444222233344 PP

                             HHHHHHSSEEEEEE-------S-HHHHHHHH...........HHHHHHHHHHHHHHEEEEEEEEEEEE- CS
                    FtsJ  80 kealserkvdlvvsDgapdvsgvhdldeylq...........sqLllaalelalkllkpggtfvlkifr 137
                               +l+er++d v++D+  +  g+  ++  l+           +   +a l+ +l+ll+++g++v  ++ 
  tr|Q388U8|Q388U8_TRYB2 348 DMHLGERRFDRVICDVPCSGDGTLRKEPSLAsswsagyvkslLPTQRALLRRGLDLLETDGILVYSTCS 416
                             577899*********974444443333333356766666544444455555566667777777755554 PP

>> tr|Q38FU9|Q38FU9_TRYB2  Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.5   0.0     6e-06    0.0034      24     137 ..     237     374 ..     223     399 .. 0.65

  Alignments for each domain:
  == domain 1  score: 16.5 bits;  conditional E-value: 6e-06
                             EEEEES-TT-HHHHHHTTT...-SEEEEEESS--............---..TT-EEEE--TTSSSHHHHHHHHHHHSSEEEEEE--- CS
                    FtsJ  24 tvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm............apl..pgvttiqgditdpetiekikealserkvdlvvsDga 96 
                             t++Dlg+aPGg s++l+++l   +  ++v l                p    + ++i+g i++++ ++   +a+++   d+    g+
  tr|Q38FU9|Q38FU9_TRYB2 237 TFLDLGCAPGGVSKYLVTELR--WSGIGVSLPVDrggiafdsswrnFPTskGRFELIEGSILEEDWQQ--HRAIKG--RDFYFVNGG 317
                             69*****************93..555555553333344555544343444468888899997776666..334444..455555555 PP

                             ----S-HHHHHHHH.................HHHHHHHHHHHHHHEEEEEEEEEEEE- CS
                    FtsJ  97 pdvsgvhdldeylq.................sqLllaalelalkllkpggtfvlkifr 137
                               v+   + +e ++                  + l ++l++a+k ++ gg++++ + r
  tr|Q38FU9|Q38FU9_TRYB2 318 -AVQDYGQREEETSgdsgelptndghpvlpwFSFLVPQLQIAVKHVRDGGVIMFVFGR 374
                             .344444444444445677778888888887778888888888888888876655444 PP

>> tr|Q4GYA9|Q4GYA9_TRYB2  Arginine N-methyltransferase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) 
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.7   0.0     5e-06    0.0029      19      82 ..      52     123 ..      35     238 .. 0.78

  Alignments for each domain:
  == domain 1  score: 16.7 bits;  conditional E-value: 5e-06
                             S-TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS--.........---...TT-EEEE--TTSSSHHHHHHHH CS
                    FtsJ  19 fkpgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm.........apl...pgvttiqgditdpetiekikea 82 
                             f ++k v+D+g+++G  s ++++  ga  kv++vD   +         +     + +t+iqg + + +  ek+   
  tr|Q4GYA9|Q4GYA9_TRYB2  52 F-KDKVVLDVGCGTGILSMFAAKA-GA-RKVIGVDCSTVavqareivrD-NgfeDVITIIQGKVEEIQLDEKVDII 123
                             4.6789******************.88.99******9997766544431.13434555558877777766666544 PP

>> tr|Q580I8|Q580I8_TRYB2  Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.4   0.4    0.0001      0.06      21     134 ..     135     380 ..     118     401 .. 0.71

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 0.0001
                             TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS--..........---.TT-EEEE--TTSSSHHHHHH..HHHHH......... CS
                    FtsJ  21 pgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm..........apl.pgvttiqgditdpetiekik..ealse......... 85 
                             +g+tv D++++PG    +++  +g++g  v+ D++            + + ++v ++ +d t+ + + ++   +a            
  tr|Q580I8|Q580I8_TRYB2 135 RGETVWDVCCSPGMKLSFIADAIGEEGSAVGTDINLDrlfaarsvmkKHRaNNVCLFVADGTSFALRTAVAvaQA--Aklyrgksnt 219
                             7899********************99********88867877766643335777777666655555554441132..1346677777 PP

                             ....................................................................................... CS
                    FtsJ  86 ....................................................................................... 85 
                                                                                                                    
  tr|Q580I8|Q580I8_TRYB2 220 dgltaleerrlrymkkrraggaadssdgtvtrdeddqvalvftcdearkrlvqsgesanqkhygfdrvlvdaecshdgslahmflgg 306
                             888888888888888888888888888888888888888888888888888888888888888888877777777777777777777 PP

                             ..........................SSEEEEEE-------S-HHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEE CS
                    FtsJ  86 ..........................rkvdlvvsDgapdvsgvhdldeylqsqLllaalelalkllkpggtfvlk 134
                                                       ++ +l + Dg ++ +    + + lq qL l+ l+ + ++l+pggt+v  
  tr|Q580I8|Q580I8_TRYB2 307 gtkrpfaghdgdadvasqainneqrmQRLNLSLPDGNEFANAEVRKVSPLQ-QLQLQLLTNGYAQLNPGGTLVYC 380
                             777777777777777777777766666677777777666655433333333.67777777777888888888743 PP

>> tr|Q388E0|Q388E0_TRYB2  Fibrillarin, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb10
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.8   0.0     4e-05     0.023      19      97 ..      66     149 ..      49     186 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.8 bits;  conditional E-value: 4e-05
                             S-TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS--.........---TT-EEEE--TTSSSHHHHHHHHHHHSSEEEEEE--- CS
                    FtsJ  19 fkpgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm.........aplpgvttiqgditdpetiekikealserkvdlvvsDga 96 
                             ++pg tv+ lgaa G     ++  +g++g+v+av   +          + ++++  i  d + p++ +++ + l    vd++ +D+a
  tr|Q388E0|Q388E0_TRYB2  66 MEPGSTVLYLGAASGTTVSHVSDLVGPEGVVYAVEFSHRsgrdleemsKRRSNIVPILEDARYPQKYRMLIPRL----VDCIFMDVA 148
                             5799*********************99988888877776666665554444899999***********999865....*******99 PP

                             - CS
                    FtsJ  97 p 97 
                              
  tr|Q388E0|Q388E0_TRYB2 149 Q 149
                             3 PP

>> tr|Q582C3|Q582C3_TRYB2  Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.7   0.0       1.1   6.5e+02      87     168 ..      61     141 ..      22     143 .. 0.70
   2 ?   11.4   0.0   0.00021      0.12      21     111 ..     310     429 ..     289     489 .. 0.58

  Alignments for each domain:
  == domain 1  score: -0.7 bits;  conditional E-value: 1.1
                             SEEEEEE-------S-HHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEE-...STTHHHHHHHHGGGEEEEEEE---------- CS
                    FtsJ  87 kvdlvvsDgapdvsgvhdldeylqsqLllaalelalkllkpggtfvlkifr...geeteallkqlkkfFekvsvvkPkssrsess 168
                              ++l++s  a    g h++  ++   L++++ +l+l++++p    v  +f    +++  ++++q+ ++F++ +++  +++r  s+
  tr|Q582C3|Q582C3_TRYB2  61 SISLILSEAA--RRGSHAVSRATMELLVEQSEQLQLRVVDPMW--VKNAFAtctNADEMRVIEQIIQKFHDKQCTDGETKRGLSQ 141
                             5667777777..6677777777777899999999999999873..3333333335666699999888888888888777776665 PP

  == domain 2  score: 11.4 bits;  conditional E-value: 0.00021
                             TT-EEEEES-TT-HHHHHHTTT..................-SEEEEEESS-----TT-EEEE--TTSSSHHHHHHHHHHH....... CS
                    FtsJ  21 pgktvvDlgaaPGgwsqvllqrl...............gakgkvvavDlqpmaplpgvttiqgditdpetiekikealse....... 85 
                             pg++v+Dl+a+PG+ +  +l  +               + +g +va D+ p                 + +++ +++ +        
  tr|Q582C3|Q582C3_TRYB2 310 PGDAVLDLCASPGNKTSLVLDYVsslrstslpssnphfH-HGCIVANDVSPP----------------RSRQLAQRLRNSsptvavt 379
                             8999***************99985555555555443332.256666666654................2222222211112222222 PP

                             ................SSEEEEEE-------S-HHHHHHHH........H CS
                    FtsJ  86 ................rkvdlvvsDgapdvsgvhdldeylq........s 111
                                             +k + ++ D   + +g+ + d++          +
  tr|Q582C3|Q582C3_TRYB2 380 qfhgqslpletgasggNKYNKILVDAPCSGEGRMQRDAMSWrmwhplrgL 429
                             22223333333344446666666665544444444444444555555552 PP

>> tr|Q388C9|Q388C9_TRYB2  Fibrillarin, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb10
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.0   0.0     7e-05      0.04      19      97 ..     142     225 ..     125     272 .. 0.81

  Alignments for each domain:
  == domain 1  score: 13.0 bits;  conditional E-value: 7e-05
                             S-TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS--.........---TT-EEEE--TTSSSHHHHHHHHHHHSSEEEEEE--- CS
                    FtsJ  19 fkpgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm.........aplpgvttiqgditdpetiekikealserkvdlvvsDga 96 
                             ++pg tv+ lgaa G     ++  +g++g+v+av   +          + ++++  i  d + p++ +++ + l    vd++ +D+a
  tr|Q388C9|Q388C9_TRYB2 142 MEPGSTVLYLGAASGTTVSHVSDLVGPEGVVYAVEFSHRsgrdleemsKRRSNIVPILEDARYPQKYRMLIPRL----VDCIFMDVA 224
                             5799*********************99988888877776666665554444899999***********999865....*******99 PP

                             - CS
                    FtsJ  97 p 97 
                              
  tr|Q388C9|Q388C9_TRYB2 225 Q 225
                             3 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (177 nodes)
Target sequences:                         8561  (4332363 residues searched)
Passed MSV filter:                       213  (0.0248803); expected 171.2 (0.02)
Passed bias filter:                      191  (0.0223105); expected 171.2 (0.02)
Passed Vit filter:                        33  (0.00385469); expected 8.6 (0.001)
Passed Fwd filter:                        15  (0.00175213); expected 0.1 (1e-05)
Initial search space (Z):               8561  [actual number of targets]
Domain search space  (domZ):              15  [number of targets reported over threshold]
# CPU time: 0.10u 0.01s 00:00:00.11 Elapsed: 00:00:00.04
# Mc/sec: 19170.71
//
[ok]