# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/FtsJ.hmm.txt # target sequence database: proteomes/Trypanosoma_brucei.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: FtsJ [M=177] Accession: PF01728.18 Description: FtsJ-like methyltransferase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 6.8e-65 217.4 0.0 1.1e-64 216.7 0.0 1.3 1 tr|Q586L7|Q586L7_TRYB2 Putative tRNA (cytidine(32)/guanosine 1.3e-54 183.9 0.0 2e-54 183.3 0.0 1.3 1 tr|Q586Q7|Q586Q7_TRYB2 Putative rRNA methyltransferase OS=Tr 4.1e-46 156.2 0.1 4.8e-46 156.0 0.1 1.0 1 tr|Q57XD9|Q57XD9_TRYB2 Ribosomal RNA methyltransferase, puta 4.9e-44 149.5 0.1 5.8e-44 149.3 0.1 1.1 1 tr|Q57Y21|Q57Y21_TRYB2 rRNA methyltransferase, putative OS=T 2.1e-32 111.6 0.0 4e-32 110.7 0.0 1.4 2 sp|Q38AH0|MTR1_TRYB2 Cap-specific mRNA (nucleoside-2'-O-)- 2e-05 23.8 0.1 4.8e-05 22.5 0.0 1.7 2 tr|Q583H8|Q583H8_TRYB2 Nucleolar protein, putative OS=Trypan 9.7e-05 21.5 0.0 0.00026 20.1 0.1 1.8 2 tr|Q57V63|Q57V63_TRYB2 Uncharacterized protein OS=Trypanosom 0.00028 20.0 0.0 0.0005 19.2 0.0 1.3 1 tr|Q38AT8|Q38AT8_TRYB2 Uncharacterized protein OS=Trypanosom 0.0005 19.2 0.0 0.001 18.2 0.0 1.4 1 tr|Q388U8|Q388U8_TRYB2 Methyltransferase, putative OS=Trypan 0.0012 17.9 0.0 0.0034 16.5 0.0 1.6 1 tr|Q38FU9|Q38FU9_TRYB2 Uncharacterized protein OS=Trypanosom 0.0021 17.2 0.0 0.0029 16.7 0.0 1.3 1 tr|Q4GYA9|Q4GYA9_TRYB2 Arginine N-methyltransferase, putativ 0.0082 15.2 0.4 0.06 12.4 0.4 2.1 1 tr|Q580I8|Q580I8_TRYB2 Uncharacterized protein OS=Trypanosom ------ inclusion threshold ------ 0.014 14.4 0.0 0.023 13.8 0.0 1.3 1 tr|Q388E0|Q388E0_TRYB2 Fibrillarin, putative OS=Trypanosoma 0.018 14.1 0.0 0.12 11.4 0.0 2.2 2 tr|Q582C3|Q582C3_TRYB2 Uncharacterized protein OS=Trypanosom 0.028 13.5 0.0 0.04 13.0 0.0 1.3 1 tr|Q388C9|Q388C9_TRYB2 Fibrillarin, putative OS=Trypanosoma Domain annotation for each sequence (and alignments): >> tr|Q586L7|Q586L7_TRYB2 Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase OS=Trypanosoma brucei bruce # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 216.7 0.0 2e-67 1.1e-64 1 177 [] 21 310 .. 21 310 .. 0.96 Alignments for each domain: == domain 1 score: 216.7 bits; conditional E-value: 2e-67 TTSHHHHHHHHHHHHH--S-TT-E...EEEES-TT-HHHHHHTTT.........................-SEEEEEESS-----TT CS FtsJ 1 yrsRsayKLleidekfklfkpgkt...vvDlgaaPGgwsqvllqrl......................gakgkvvavDlqpmaplpg 62 yr+RsayKLl+++e+f+++++++ vvDl+aaPG+wsqvl+++l +++++vavDlq+m p++g tr|Q586L7|Q586L7_TRYB2 21 YRARSAYKLLQLHEEFGILRREEIrtgVVDLCAAPGSWSQVLSNHLcgsqpgsaaeacegdeainseaSQRPRIVAVDLQEMMPIDG 107 9******************85533447*******************9999999999988887776644226**************** PP -EEEE--TTSSSHHHHHHHHHHH................................................................ CS FtsJ 63 vttiqgditdpetiekikealse................................................................ 85 v+++qgdit++ t+++i ++l++ tr|Q586L7|Q586L7_TRYB2 108 VQLLQGDITSEWTAREIIRLLNGdsssvpecsdatalstagaindfnngrgnnvseegkssqqrsdcgvglmnernnasecvdgdnn 194 **********************9**************************************************************** PP ........................SSEEEEEE-------S-HHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEE-STTHHHHHHHH CS FtsJ 86 ........................rkvdlvvsDgapdvsgvhdldeylqsqLllaalelalkllkpggtfvlkifrgeeteallkql 148 rk+dlvv+Dgapdv+g+h+ldeylq +Lllaal++++ +l++ggtfv+k+frg++t +l+++ tr|Q586L7|Q586L7_TRYB2 195 nnnsnnnddrnggdagastrpvagRKADLVVCDGAPDVTGMHELDEYLQHHLLLAALNITTFVLRRGGTFVTKMFRGPNTPFLVAKA 281 *************************************************************************************** PP GGGEEEEEEE----------EEEEEEEEE CS FtsJ 149 kkfFekvsvvkPkssrsesseeflvcrgf 177 + fF++v+++kPkssr++s e+f+vc+++ tr|Q586L7|Q586L7_TRYB2 282 EVFFRQVTIAKPKSSRNASMEAFMVCQNY 310 **************************996 PP >> tr|Q586Q7|Q586Q7_TRYB2 Putative rRNA methyltransferase OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=1854 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 183.3 0.0 3.6e-57 2e-54 1 177 [] 25 201 .. 25 201 .. 0.99 Alignments for each domain: == domain 1 score: 183.3 bits; conditional E-value: 3.6e-57 TTSHHHHHHHHHHHHH--S-TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS-----TT-EEEE--TTSSSHHHHHHHHHHHSS CS FtsJ 1 yrsRsayKLleidekfklfkpgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpmaplpgvttiqgditdpetiekikealserk 87 +r+Rsa+KL +++ k++++++ + vDl+aaPG+w+qv+++++ ++k+v+vDl p+ap+ gv+t+ gdit+++t++ i ++l++++ tr|Q586Q7|Q586Q7_TRYB2 25 FRARSAFKLVQLNRKYDFLSKCRVLVDLCAAPGSWCQVAAKHMPVGSKIVGVDLVPIAPIRGVKTFVGDITEEKTKKIIMTYLKREP 111 79***************99************************999***************************************** PP EEEEEE-------S-HHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEE-STTHHHHHHHHGGGEEEEEEE----------EEEEEE CS FtsJ 88 vdlvvsDgapdvsgvhdldeylqsqLllaalelalkllkpggtfvlkifrgeeteallkqlkkfFekvsvvkPkssrsesseeflvc 174 vd+v++Dgap+v gv++ d + q +L+l a +la+kll+pgg fv+k+fr++++ +l+ +k++F+kv+ +kP +sr es+e+f+ c tr|Q586Q7|Q586Q7_TRYB2 112 VDCVIHDGAPNVGGVWSRDLFEQNSLVLHAAKLASKLLRPGGWFVTKVFRSQDFHKLMWVMKQLFDKVEATKPLASRMESAEIFVTC 198 *************************************************************************************** PP EEE CS FtsJ 175 rgf 177 g+ tr|Q586Q7|Q586Q7_TRYB2 199 AGY 201 986 PP >> tr|Q57XD9|Q57XD9_TRYB2 Ribosomal RNA methyltransferase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10. # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 156.0 0.1 8.4e-49 4.8e-46 1 177 [] 34 218 .. 34 218 .. 0.92 Alignments for each domain: == domain 1 score: 156.0 bits; conditional E-value: 8.4e-49 TTSHHHHHHHHHHHHH--S-..TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS-----.TT-EEEE--TTSSSHHHHHHHHHH CS FtsJ 1 yrsRsayKLleidekfklfk..pgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpmapl.pgvttiqgditdpetiekikeals 84 y++Rsa+KLle+d+kf lf+ +++ vvD+g++PG+w qv+ +r+g k+ v++vD+ +a g +iqgd+t+p+++e+++ + tr|Q57XD9|Q57XD9_TRYB2 34 YVARSAFKLLEMDDKFTLFSrgNTRVVVDIGCSPGSWLQVIRERCGDKCAVFGVDVLRVASTvTGAVCIQGDFTNPAVREELLARMV 120 99*****************8455566******************************9996666*****************9998777 PP H....SSEEEEEE-------S-HHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEE-STTHH.HHHHHHGGGEEEEEEE-------- CS FtsJ 85 e....rkvdlvvsDgapdvsgvhdldeylqsqLllaalelalkllkpggtfvlkifrgeete.allkqlkkfFekvsvvkPkssrse 166 vd+v+sD++ + ++ d +q +L ++al +al++l pgg+fv+k++ ++ + +l +++ + F + +++kP+ssr + tr|Q57XD9|Q57XD9_TRYB2 121 TvraaGVVDVVTSDMCLNRGTGSTSDRQKQEELNRSALAFALEQLVPGGNFVCKVLGSPTAYeELRRDTCRWFVRTDICKPSSSRLT 207 7666667*********988888***********************************77777488888999**************** PP --EEEEEEEEE CS FtsJ 167 sseeflvcrgf 177 s e+f+vcrg+ tr|Q57XD9|Q57XD9_TRYB2 208 SDEAFMVCRGK 218 *********85 PP >> tr|Q57Y21|Q57Y21_TRYB2 rRNA methyltransferase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 149.3 0.1 1e-46 5.8e-44 1 177 [] 2 225 .. 2 225 .. 0.85 Alignments for each domain: == domain 1 score: 149.3 bits; conditional E-value: 1e-46 TTSHHHHHHHHHHHHH--S-.TT-EEEEES-TT-HHHHHHTTT.............-SEEEEEESS-----TT-EEEE--T.TSSSH CS FtsJ 1 yrsRsayKLleidekfklfk.pgktvvDlgaaPGgwsqvllqrlga..........kgkvvavDlqpmaplpgvttiqgdi.tdpet 75 yr+RsayKLle+d+kf+lf +tvvDl+aaPGg+s+v+lqr++a k+ v+a+D++pm+ ++++q++i ++++ tr|Q57Y21|Q57Y21_TRYB2 2 YRCRSAYKLLELDDKFSLFGgCCRTVVDLAAAPGGFSEVALQRMTAaedvtsrppvKPLVIAFDTRPMKAARDLHVVQCNInDHKRV 88 9******************8899*********************5555555555557************************556778 PP HHHHHHHHHH........SSEEEEEE-------S-HHHHHHHH..HHHHHHHHHHHHHHEE.......................... CS FtsJ 76 iekikealse........rkvdlvvsDgapdvsgvhdldeylq..sqLllaalelalkllk.......................... 126 i ++e++++ r+vd+v++Dg+ +v h+ +++ q++ al+la++l+ tr|Q57Y21|Q57Y21_TRYB2 89 IASVEEFIQRrgvgdgadRQVDVVLHDGV-SVAKSHSAFSVTYaqNQMAVGALRLACALFLlssqpagtrqppraedglassskaep 174 88999988889******************.665556555554433466666666666554445566668888888888889999998 PP EEEEEEEEEE-STTHHHHHHHHGGGEEEEEEE----------EEEEEEEEE CS FtsJ 127 pggtfvlkifrgeeteallkqlkkfFekvsvvkPkssrsesseeflvcrgf 177 +g tfv+k++r+++++++l+++k++F++vsv++P++++ +sse+++v+rgf tr|Q57Y21|Q57Y21_TRYB2 175 QGPTFVTKAMRSAHFNQVLSAMKAYFRHVSVHRPAECNAASSETYVVARGF 225 999**********************************************98 PP >> sp|Q38AH0|MTR1_TRYB2 Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 OS=Trypanosoma brucei brucei (strain 9 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 110.7 0.0 7e-35 4e-32 1 177 [] 88 293 .. 88 293 .. 0.88 2 ? -3.6 0.0 8.6 4.9e+03 48 61 .. 331 347 .. 322 366 .. 0.63 Alignments for each domain: == domain 1 score: 110.7 bits; conditional E-value: 7e-35 TTSHHHHHHHHHHHHH--S-..TT-E........EEEES-TT-HHHHHHTTT.......-SEEEEEESS--......---TT-EEE... CS FtsJ 1 yrsRsayKLleidekfklfk..pgkt........vvDlgaaPGgwsqvllqrlga....kgkvvavDlqpm......aplpgvtti... 66 +r+R+++KL e e+++l + +g++ +vD++ +PG++sq l g+ + + ++++l+++ + lp +++ sp|Q38AH0|MTR1_TRYB2 88 FRNRAGHKLHETMEAVGLWEylKGGAtrakgtftFVDVCGGPGAFSQALFAM-GKehklRLRGFGLTLRNVkgldwyTDLPSRSFFpcy 175 79***************88766554457788888***************887.4435445999*****999666666455666666889 PP ....E--TTSSSHHHHHHHHHHHSSEEEEEE------.-S-HHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEE-.STTHH.HHHHHH CS FtsJ 67 ....qgditdpetiekikealserkvdlvvsDgapdv.sgvhdldeylqsqLllaalelalkllkpggtfvlkifr.geete.allkql 148 +gd+++ e+ie + ++ ++ v lvv+Dg++dv + v +++e+++++++ ++ a+kll+pgg+fvlk+f+ ++ ++ a+l + sp|Q38AH0|MTR1_TRYB2 176 gidgTGDVFKLENIESLCSLTCKENVRLVVADGGFDVpTEVVNFQETISCRIVYGQWLSAVKLLRPGGCFVLKLFDcFSPFTrAILFLT 264 99***********************************56669**********************************9777775888889 PP GGGEEEEEEE----------EEEEEEEEE CS FtsJ 149 kkfFekvsvvkPkssrsesseeflvcrgf 177 +++e+v+vvkP++sr +se++lvc gf sp|Q38AH0|MTR1_TRYB2 265 THLYESVQVVKPRHSRVVNSERYLVCIGF 293 9*************************987 PP == domain 2 score: -3.6 bits; conditional E-value: 8.6 EEEEEESS-----...T CS FtsJ 48 kvvavDlqpmapl...p 61 k+++ D+ m+ + sp|Q38AH0|MTR1_TRYB2 331 KIFGADVERMSATiasN 347 67788887773322333 PP >> tr|Q583H8|Q583H8_TRYB2 Nucleolar protein, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 G # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.5 0.0 8.4e-08 4.8e-05 23 137 .. 258 386 .. 217 406 .. 0.72 2 ? -3.2 0.0 6.7 3.8e+03 124 147 .. 441 470 .. 429 492 .. 0.61 Alignments for each domain: == domain 1 score: 22.5 bits; conditional E-value: 8.4e-08 -EEEEES-TT-HHHHHHTTT...-SEEEEEESS-----TT-EEEE--TTSSSHHHHHHHHHHH.......SSEEEEEE----..... CS FtsJ 23 ktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpmaplpgvttiqgditdpetiekikealse.......rkvdlvvsDgap..... 97 ++v+D +aaPGg + +++q ++++g+++a D+ + p+ ++++++ ++ + +++ + ++ + +d ++ D tr|Q583H8|Q583H8_TRYB2 258 ERVLDMAAAPGGKTTYIAQLMKNTGVIFANDVSE----PRTKSLNANLQRLGVTNTVVTNYDGvgfekvmKNFDRILLDAPCtgsgi 340 67*******************999********88....6666666666666666666655544555556655666666654323333 PP .......---S-HHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEE- CS FtsJ 98 .......dvsgvhdldeylqsqLllaalelalkllkpggtfvlkifr 137 ++s + d ++sqL ++ l a++ ++ gg +v ++ tr|Q583H8|Q583H8_TRYB2 341 isrdksiKTSK-QYEDVQRASQLQRSLLLSAIDAVRVGGYIVYSTCS 386 33332103333.445555559******************99977665 PP == domain 2 score: -3.2 bits; conditional E-value: 6.7 HEEEEEEEEEEEE-......STTHHHHHHH CS FtsJ 124 llkpggtfvlkifr......geeteallkq 147 + + +g fv+k+ + g++t++l k+ tr|Q583H8|Q583H8_TRYB2 441 VHNMDGFFVCKLKKlsnnagGPSTNGLKKE 470 555677888887776666655555555554 PP >> tr|Q57V63|Q57V63_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.7 0.0 9.2 5.2e+03 97 120 .. 68 91 .. 66 98 .. 0.81 2 ! 20.1 0.1 4.5e-07 0.00026 20 137 .. 151 289 .. 119 316 .. 0.66 Alignments for each domain: == domain 1 score: -3.7 bits; conditional E-value: 9.2 ----S-HHHHHHHHHHHHHHHHHH CS FtsJ 97 pdvsgvhdldeylqsqLllaalel 120 p+v +++ ey++s+Ll aal + tr|Q57V63|Q57V63_TRYB2 68 PSVPCATAVSEYVRSRLLHAALPV 91 56666788999999****999976 PP == domain 2 score: 20.1 bits; conditional E-value: 4.5e-07 -TT-EEEEES-TT-HHHHHHTTT......-SEEEEEESS--...........---TT-EEE..E--TTSSSHHHHHHHHHHHSSEEE CS FtsJ 20 kpgktvvDlgaaPGgwsqvllqrl...gakgkvvavDlqpm...........aplpgvtti..qgditdpetiekikealserkvdl 90 pg++v+D +aaPG+ + +l+ + +++g+vva Dl+ +p + ++i + d t+ + k e k+d tr|Q57V63|Q57V63_TRYB2 151 APGNRVLDMCAAPGSKTSQILEAVissNQDGVVVANDLNVArldvllhqtarSPGAHPHLIvtNYDGTQFPLLP--K----EDKFDR 231 47899***************9999655446********988777776665432222333331133333333333..2....3689** PP EEE-------S-HHHHHHHH..........HHHHHHHHHH...HHHHEEEEEEEEEEEE- CS FtsJ 91 vvsDgapdvsgvhdldeylq..........sqLllaalel...alkllkpggtfvlkifr 137 v++D+ +sg +l + + ++L ++++ ++ l+k+gg++v ++ tr|Q57V63|Q57V63_TRYB2 232 VLCDVM--CSGDGTLRKSMDmwprwntvhgADLHVTQVRVltrGMMLCKKGGIVVYSTCS 289 ****98..6776666666666666777777666666666622233577788887776666 PP >> tr|Q38AT8|Q38AT8_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.2 0.0 8.7e-07 0.0005 20 139 .. 168 345 .. 154 366 .. 0.81 Alignments for each domain: == domain 1 score: 19.2 bits; conditional E-value: 8.7e-07 -TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS--.---...TT-EEEE--TTSSSHHHHHHHHHHH................. CS FtsJ 20 kpgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm.apl...pgvttiqgditdpetiekikealse................. 85 +p+++++D +a+PG+ + +l lg +kvv D p+ + ++ di ++++ ++ + +++ tr|Q38AT8|Q38AT8_TRYB2 168 QPTDKCLDMCASPGSKTAQILVSLGR-HKVVPHDSDASpFPFdydSEGLVVANDIDTKRANMLVHQ-VKRmrllfpfalftnhdaqf 252 58899***************999997.99*****98876555543444455899988888887774.56678999999999999*** PP ............................SSEEEEEE-------S-.HHHHHHHH.......HHHHHHHHHH...HHHHEEEEEEEEE CS FtsJ 86 ............................rkvdlvvsDgapdvsgv.hdldeylq.......sqLllaalel...alkllkpggtfvl 133 ++d +++D++ + g+ ++ +++l+ ++L + ++++ a++ll+ gg +v tr|Q38AT8|Q38AT8_TRYB2 253 fpnmvltpgeaqphtcgqqttgddgateLRFDKILCDVVCSGDGTiRKAPHILKmwspreaISLQKVQIQIalrACHLLRVGGRLVY 339 **************************9999********96666666777777779999999788888888844455799*****998 PP EEE-ST CS FtsJ 134 kifrge 139 ++ tr|Q38AT8|Q38AT8_TRYB2 340 STCSMN 345 877743 PP >> tr|Q388U8|Q388U8_TRYB2 Methyltransferase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 G # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.2 0.0 1.8e-06 0.001 19 137 .. 262 416 .. 242 441 .. 0.67 Alignments for each domain: == domain 1 score: 18.2 bits; conditional E-value: 1.8e-06 S-TT-EEEEES-TT-HHHHHHTTT....................-SEEEEEESS--...---..TT-EEEE--T....TSSSHHHHH CS FtsJ 19 fkpgktvvDlgaaPGgwsqvllqrl.................gakgkvvavDlqpm...apl..pgvttiqgdi....tdpetieki 79 ++p +tv+D +aaPG+ + +l ++ ++k +v a + p + p+v + ++d + + tr|Q388U8|Q388U8_TRYB2 262 IQPHHTVLDMCAAPGSKTLQALDEMlkngwnssavssgvmvaNEKDRVKATQTLPArlkR-YhaPNVICTRCDAvqwpRLLCPTTQG 347 46889***********99999888888888777777766665336888888888885532.25799999999985444222233344 PP HHHHHHSSEEEEEE-------S-HHHHHHHH...........HHHHHHHHHHHHHHEEEEEEEEEEEE- CS FtsJ 80 kealserkvdlvvsDgapdvsgvhdldeylq...........sqLllaalelalkllkpggtfvlkifr 137 +l+er++d v++D+ + g+ ++ l+ + +a l+ +l+ll+++g++v ++ tr|Q388U8|Q388U8_TRYB2 348 DMHLGERRFDRVICDVPCSGDGTLRKEPSLAsswsagyvkslLPTQRALLRRGLDLLETDGILVYSTCS 416 577899*********974444443333333356766666544444455555566667777777755554 PP >> tr|Q38FU9|Q38FU9_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.5 0.0 6e-06 0.0034 24 137 .. 237 374 .. 223 399 .. 0.65 Alignments for each domain: == domain 1 score: 16.5 bits; conditional E-value: 6e-06 EEEEES-TT-HHHHHHTTT...-SEEEEEESS--............---..TT-EEEE--TTSSSHHHHHHHHHHHSSEEEEEE--- CS FtsJ 24 tvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm............apl..pgvttiqgditdpetiekikealserkvdlvvsDga 96 t++Dlg+aPGg s++l+++l + ++v l p + ++i+g i++++ ++ +a+++ d+ g+ tr|Q38FU9|Q38FU9_TRYB2 237 TFLDLGCAPGGVSKYLVTELR--WSGIGVSLPVDrggiafdsswrnFPTskGRFELIEGSILEEDWQQ--HRAIKG--RDFYFVNGG 317 69*****************93..555555553333344555544343444468888899997776666..334444..455555555 PP ----S-HHHHHHHH.................HHHHHHHHHHHHHHEEEEEEEEEEEE- CS FtsJ 97 pdvsgvhdldeylq.................sqLllaalelalkllkpggtfvlkifr 137 v+ + +e ++ + l ++l++a+k ++ gg++++ + r tr|Q38FU9|Q38FU9_TRYB2 318 -AVQDYGQREEETSgdsgelptndghpvlpwFSFLVPQLQIAVKHVRDGGVIMFVFGR 374 .344444444444445677778888888887778888888888888888876655444 PP >> tr|Q4GYA9|Q4GYA9_TRYB2 Arginine N-methyltransferase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.7 0.0 5e-06 0.0029 19 82 .. 52 123 .. 35 238 .. 0.78 Alignments for each domain: == domain 1 score: 16.7 bits; conditional E-value: 5e-06 S-TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS--.........---...TT-EEEE--TTSSSHHHHHHHH CS FtsJ 19 fkpgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm.........apl...pgvttiqgditdpetiekikea 82 f ++k v+D+g+++G s ++++ ga kv++vD + + + +t+iqg + + + ek+ tr|Q4GYA9|Q4GYA9_TRYB2 52 F-KDKVVLDVGCGTGILSMFAAKA-GA-RKVIGVDCSTVavqareivrD-NgfeDVITIIQGKVEEIQLDEKVDII 123 4.6789******************.88.99******9997766544431.13434555558877777766666544 PP >> tr|Q580I8|Q580I8_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 12.4 0.4 0.0001 0.06 21 134 .. 135 380 .. 118 401 .. 0.71 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.0001 TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS--..........---.TT-EEEE--TTSSSHHHHHH..HHHHH......... CS FtsJ 21 pgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm..........apl.pgvttiqgditdpetiekik..ealse......... 85 +g+tv D++++PG +++ +g++g v+ D++ + + ++v ++ +d t+ + + ++ +a tr|Q580I8|Q580I8_TRYB2 135 RGETVWDVCCSPGMKLSFIADAIGEEGSAVGTDINLDrlfaarsvmkKHRaNNVCLFVADGTSFALRTAVAvaQA--Aklyrgksnt 219 7899********************99********88867877766643335777777666655555554441132..1346677777 PP ....................................................................................... CS FtsJ 86 ....................................................................................... 85 tr|Q580I8|Q580I8_TRYB2 220 dgltaleerrlrymkkrraggaadssdgtvtrdeddqvalvftcdearkrlvqsgesanqkhygfdrvlvdaecshdgslahmflgg 306 888888888888888888888888888888888888888888888888888888888888888888877777777777777777777 PP ..........................SSEEEEEE-------S-HHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEE CS FtsJ 86 ..........................rkvdlvvsDgapdvsgvhdldeylqsqLllaalelalkllkpggtfvlk 134 ++ +l + Dg ++ + + + lq qL l+ l+ + ++l+pggt+v tr|Q580I8|Q580I8_TRYB2 307 gtkrpfaghdgdadvasqainneqrmQRLNLSLPDGNEFANAEVRKVSPLQ-QLQLQLLTNGYAQLNPGGTLVYC 380 777777777777777777777766666677777777666655433333333.67777777777888888888743 PP >> tr|Q388E0|Q388E0_TRYB2 Fibrillarin, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb10 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.0 4e-05 0.023 19 97 .. 66 149 .. 49 186 .. 0.81 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 4e-05 S-TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS--.........---TT-EEEE--TTSSSHHHHHHHHHHHSSEEEEEE--- CS FtsJ 19 fkpgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm.........aplpgvttiqgditdpetiekikealserkvdlvvsDga 96 ++pg tv+ lgaa G ++ +g++g+v+av + + ++++ i d + p++ +++ + l vd++ +D+a tr|Q388E0|Q388E0_TRYB2 66 MEPGSTVLYLGAASGTTVSHVSDLVGPEGVVYAVEFSHRsgrdleemsKRRSNIVPILEDARYPQKYRMLIPRL----VDCIFMDVA 148 5799*********************99988888877776666665554444899999***********999865....*******99 PP - CS FtsJ 97 p 97 tr|Q388E0|Q388E0_TRYB2 149 Q 149 3 PP >> tr|Q582C3|Q582C3_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.7 0.0 1.1 6.5e+02 87 168 .. 61 141 .. 22 143 .. 0.70 2 ? 11.4 0.0 0.00021 0.12 21 111 .. 310 429 .. 289 489 .. 0.58 Alignments for each domain: == domain 1 score: -0.7 bits; conditional E-value: 1.1 SEEEEEE-------S-HHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEE-...STTHHHHHHHHGGGEEEEEEE---------- CS FtsJ 87 kvdlvvsDgapdvsgvhdldeylqsqLllaalelalkllkpggtfvlkifr...geeteallkqlkkfFekvsvvkPkssrsess 168 ++l++s a g h++ ++ L++++ +l+l++++p v +f +++ ++++q+ ++F++ +++ +++r s+ tr|Q582C3|Q582C3_TRYB2 61 SISLILSEAA--RRGSHAVSRATMELLVEQSEQLQLRVVDPMW--VKNAFAtctNADEMRVIEQIIQKFHDKQCTDGETKRGLSQ 141 5667777777..6677777777777899999999999999873..3333333335666699999888888888888777776665 PP == domain 2 score: 11.4 bits; conditional E-value: 0.00021 TT-EEEEES-TT-HHHHHHTTT..................-SEEEEEESS-----TT-EEEE--TTSSSHHHHHHHHHHH....... CS FtsJ 21 pgktvvDlgaaPGgwsqvllqrl...............gakgkvvavDlqpmaplpgvttiqgditdpetiekikealse....... 85 pg++v+Dl+a+PG+ + +l + + +g +va D+ p + +++ +++ + tr|Q582C3|Q582C3_TRYB2 310 PGDAVLDLCASPGNKTSLVLDYVsslrstslpssnphfH-HGCIVANDVSPP----------------RSRQLAQRLRNSsptvavt 379 8999***************99985555555555443332.256666666654................2222222211112222222 PP ................SSEEEEEE-------S-HHHHHHHH........H CS FtsJ 86 ................rkvdlvvsDgapdvsgvhdldeylq........s 111 +k + ++ D + +g+ + d++ + tr|Q582C3|Q582C3_TRYB2 380 qfhgqslpletgasggNKYNKILVDAPCSGEGRMQRDAMSWrmwhplrgL 429 22223333333344446666666665544444444444444555555552 PP >> tr|Q388C9|Q388C9_TRYB2 Fibrillarin, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb10 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.0 7e-05 0.04 19 97 .. 142 225 .. 125 272 .. 0.81 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 7e-05 S-TT-EEEEES-TT-HHHHHHTTT...-SEEEEEESS--.........---TT-EEEE--TTSSSHHHHHHHHHHHSSEEEEEE--- CS FtsJ 19 fkpgktvvDlgaaPGgwsqvllqrlgakgkvvavDlqpm.........aplpgvttiqgditdpetiekikealserkvdlvvsDga 96 ++pg tv+ lgaa G ++ +g++g+v+av + + ++++ i d + p++ +++ + l vd++ +D+a tr|Q388C9|Q388C9_TRYB2 142 MEPGSTVLYLGAASGTTVSHVSDLVGPEGVVYAVEFSHRsgrdleemsKRRSNIVPILEDARYPQKYRMLIPRL----VDCIFMDVA 224 5799*********************99988888877776666665554444899999***********999865....*******99 PP - CS FtsJ 97 p 97 tr|Q388C9|Q388C9_TRYB2 225 Q 225 3 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (177 nodes) Target sequences: 8561 (4332363 residues searched) Passed MSV filter: 213 (0.0248803); expected 171.2 (0.02) Passed bias filter: 191 (0.0223105); expected 171.2 (0.02) Passed Vit filter: 33 (0.00385469); expected 8.6 (0.001) Passed Fwd filter: 15 (0.00175213); expected 0.1 (1e-05) Initial search space (Z): 8561 [actual number of targets] Domain search space (domZ): 15 [number of targets reported over threshold] # CPU time: 0.10u 0.01s 00:00:00.11 Elapsed: 00:00:00.04 # Mc/sec: 19170.71 // [ok]