# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/GCD14.hmm.txt
# target sequence database:        proteomes/Caenorhabditis_elegans.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       GCD14  [M=247]
Accession:   PF08704.9
Description: tRNA methyltransferase complex GCD14 subunit
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    3.1e-72  243.4   0.0    3.7e-72  243.1   0.0    1.1  1  tr|G5EGR8|G5EGR8_CAEEL  tRNA (adenine(58)-N(1))-methyltransfe
    0.00077   19.4   0.0     0.0012   18.7   0.0    1.3  1  sp|Q22053|FBRL_CAEEL    rRNA 2'-O-methyltransferase fibrillar
  ------ inclusion threshold ------
      0.042   13.7   1.0      0.078   12.8   1.0    1.5  1  tr|Q9N3T7|Q9N3T7_CAEEL  Uncharacterized protein OS=Caenorhabd
      0.069   13.0   0.0      0.091   12.6   0.0    1.2  1  sp|Q27873|PIMT_CAEEL    Protein-L-isoaspartate O-methyltransf


Domain annotation for each sequence (and alignments):
>> tr|G5EGR8|G5EGR8_CAEEL  tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A OS=Caenorhabditis elegans
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  243.1   0.0   7.5e-76   3.7e-72       1     246 [.      67     306 ..      67     307 .. 0.90

  Alignments for each domain:
  == domain 1  score: 243.1 bits;  conditional E-value: 7.5e-76
                   GCD14   1 gfvyvlaptPeLWtlaLphrtqilytaDisliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefre 87 
                             g+vy+l+pt +LWt aLp rtqilytaD + i   L+ kpGsv++esGtGsgslshaia tvaPtGhl+t +  e+r++k +eef+ 
  tr|G5EGR8|G5EGR8_CAEEL  67 GYVYILRPTSDLWTRALPRRTQILYTADCAQILSLLDAKPGSVICESGTGSGSLSHAIALTVAPTGHLYTHDIDETRTHKVLEEFKV 153
                             89************************************************************************************* PP

                   GCD14  88 helsqlvtvthrDvckeGfdeevsgkvDavfLDlPaPweaiphaakal.kkeggrlCsfsPCieqvqrtceaLrelgfteietlevl 173
                             h+l +++t  +r+vc++Gf  +v++ +D vfLD+PaPweaip aak + + +ggrl sfsPC+eqvqr+c a+++ gf+ iet+e+ 
  tr|G5EGR8|G5EGR8_CAEEL 154 HGLGSVTTAVVRNVCTSGF--HVENAADGVFLDVPAPWEAIPFAAKSIfRARGGRLVSFSPCLEQVQRACLAMAAAGFVSIETIELV 238
                             *******************..999*******************999998************************************** PP

                   GCD14 174 lrtyevrkskleeidlaekrleenerkriekakrrkaskdakvedkssks...stevllkPvselkghtgyLtfat 246
                               + ++  ++ ++++++e+  +   +       +rk + d ++ ++ss++    t  ++ P     +htgyLt at
  tr|G5EGR8|G5EGR8_CAEEL 239 PEQKKIVSQHRQTLEEFEELGDAYPK-------ERKRNVDGTIVEQSSSAiprITIAIVYP-YSQPTHTGYLTHAT 306
                             99988888888887777776666543.......4455555555555555545445566777.56789******997 PP

>> sp|Q22053|FBRL_CAEEL  rRNA 2'-O-methyltransferase fibrillarin OS=Caenorhabditis elegans OX=6239 GN=fib-1 PE=2 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.7   0.0   2.4e-07    0.0012      36     151 ..     186     302 ..     176     340 .. 0.70

  Alignments for each domain:
  == domain 1  score: 18.7 bits;  conditional E-value: 2.4e-07
                 GCD14  36 LelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtvthrDvc.keGfdeevsgkvDavfLDlPa 123
                            ++kpG++ +  G+ sg+  +  +  v+P G ++++ef ++  +  +    ++    +v   + D+   + + + + g vD +f D+ +
  sp|Q22053|FBRL_CAEEL 186 THIKPGTKLLYLGAASGTTVSHCSDVVGPEGIVYAVEFSHRSGRDLLG-VAKK--RPNVVPIVEDARhPHKY-RMLVGMVDVIFSDVAQ 270
                           579***************9999****************7644433333.3332..33444445566624555.5677************ PP

                 GCD14 124 Pwea...iphaakalkkeggrlCsf.sPCieq 151
                           P++a     +a + l++ g  + s  + Ci+ 
  sp|Q22053|FBRL_CAEEL 271 PDQArivALNAQNFLRNGGHAVISIkANCIDS 302
                           **994322355666766655555542567765 PP

>> tr|Q9N3T7|Q9N3T7_CAEEL  Uncharacterized protein OS=Caenorhabditis elegans OX=6239 GN=CELE_Y47G6A.13 PE=1 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   1.0   1.6e-05     0.078     103     232 ..     212     344 ..     196     412 .. 0.76

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 1.6e-05
                   GCD14 103 keGf.deevsgkvDavfLDlPaPweaiphaakal..kkeggrlCsfsPCieqvqrtceaLrelgfteietlevllrtyevrksklee 186
                             ++G  d+ v      v+L l  Pw  +++ ++ +  kk+   l  f    + ++   e Lr l + +    e  ++   +  ++l+ 
  tr|Q9N3T7|Q9N3T7_CAEEL 212 EQGRcDDLVAMIYSIVYLTLGLPWSNLKDEKEIMsmKKSTKDLALFEDLPDELKSIFEYLRTLSYADRPNYEKIYNLLMAAITRLKI 298
                             55652333444456689**********999888764777788******************************999998888777776 PP

                   GCD14 187 idlaekrleenerkriekakrrkaskdakvedkssksstevllkPv 232
                               l   + e++e +r+ ka++++++k++k ++++++ ++e+ +  +
  tr|Q9N3T7|Q9N3T7_CAEEL 299 NFLDPYEWEDDEMERMAKAEKEEKEKEEKEKKEKENKENELSADSM 344
                             6666666666666666666655555444444444443334333333 PP

>> sp|Q27873|PIMT_CAEEL  Protein-L-isoaspartate O-methyltransferase OS=Caenorhabditis elegans OX=6239 GN=pcm-1 PE=2 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   1.8e-05     0.091      37      93 ..      75     131 ..      64     181 .. 0.82

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 1.8e-05
                 GCD14  37 elkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsql 93 
                           +l  G+++++ G Gsg l+  +a  v+  G +  +e+  q +e + ++ r+h+ +ql
  sp|Q27873|PIMT_CAEEL  75 HLVAGAKALDVGSGSGYLTVCMAMMVGRNGTVVGIEHMPQLVELSEKNIRKHHSEQL 131
                           6889**********************************************9987553 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (247 nodes)
Target sequences:                        20008  (8229220 residues searched)
Passed MSV filter:                      1301  (0.065024); expected 400.2 (0.02)
Passed bias filter:                      826  (0.0412835); expected 400.2 (0.02)
Passed Vit filter:                       101  (0.00504798); expected 20.0 (0.001)
Passed Fwd filter:                        33  (0.00164934); expected 0.2 (1e-05)
Initial search space (Z):              20008  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.38u 0.01s 00:00:00.39 Elapsed: 00:00:00.13
# Mc/sec: 15635.52
//
[ok]