# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/GCD14.hmm.txt # target sequence database: proteomes/Caenorhabditis_elegans.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: GCD14 [M=247] Accession: PF08704.9 Description: tRNA methyltransferase complex GCD14 subunit Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.1e-72 243.4 0.0 3.7e-72 243.1 0.0 1.1 1 tr|G5EGR8|G5EGR8_CAEEL tRNA (adenine(58)-N(1))-methyltransfe 0.00077 19.4 0.0 0.0012 18.7 0.0 1.3 1 sp|Q22053|FBRL_CAEEL rRNA 2'-O-methyltransferase fibrillar ------ inclusion threshold ------ 0.042 13.7 1.0 0.078 12.8 1.0 1.5 1 tr|Q9N3T7|Q9N3T7_CAEEL Uncharacterized protein OS=Caenorhabd 0.069 13.0 0.0 0.091 12.6 0.0 1.2 1 sp|Q27873|PIMT_CAEEL Protein-L-isoaspartate O-methyltransf Domain annotation for each sequence (and alignments): >> tr|G5EGR8|G5EGR8_CAEEL tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A OS=Caenorhabditis elegans # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 243.1 0.0 7.5e-76 3.7e-72 1 246 [. 67 306 .. 67 307 .. 0.90 Alignments for each domain: == domain 1 score: 243.1 bits; conditional E-value: 7.5e-76 GCD14 1 gfvyvlaptPeLWtlaLphrtqilytaDisliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefre 87 g+vy+l+pt +LWt aLp rtqilytaD + i L+ kpGsv++esGtGsgslshaia tvaPtGhl+t + e+r++k +eef+ tr|G5EGR8|G5EGR8_CAEEL 67 GYVYILRPTSDLWTRALPRRTQILYTADCAQILSLLDAKPGSVICESGTGSGSLSHAIALTVAPTGHLYTHDIDETRTHKVLEEFKV 153 89************************************************************************************* PP GCD14 88 helsqlvtvthrDvckeGfdeevsgkvDavfLDlPaPweaiphaakal.kkeggrlCsfsPCieqvqrtceaLrelgfteietlevl 173 h+l +++t +r+vc++Gf +v++ +D vfLD+PaPweaip aak + + +ggrl sfsPC+eqvqr+c a+++ gf+ iet+e+ tr|G5EGR8|G5EGR8_CAEEL 154 HGLGSVTTAVVRNVCTSGF--HVENAADGVFLDVPAPWEAIPFAAKSIfRARGGRLVSFSPCLEQVQRACLAMAAAGFVSIETIELV 238 *******************..999*******************999998************************************** PP GCD14 174 lrtyevrkskleeidlaekrleenerkriekakrrkaskdakvedkssks...stevllkPvselkghtgyLtfat 246 + ++ ++ ++++++e+ + + +rk + d ++ ++ss++ t ++ P +htgyLt at tr|G5EGR8|G5EGR8_CAEEL 239 PEQKKIVSQHRQTLEEFEELGDAYPK-------ERKRNVDGTIVEQSSSAiprITIAIVYP-YSQPTHTGYLTHAT 306 99988888888887777776666543.......4455555555555555545445566777.56789******997 PP >> sp|Q22053|FBRL_CAEEL rRNA 2'-O-methyltransferase fibrillarin OS=Caenorhabditis elegans OX=6239 GN=fib-1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.7 0.0 2.4e-07 0.0012 36 151 .. 186 302 .. 176 340 .. 0.70 Alignments for each domain: == domain 1 score: 18.7 bits; conditional E-value: 2.4e-07 GCD14 36 LelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtvthrDvc.keGfdeevsgkvDavfLDlPa 123 ++kpG++ + G+ sg+ + + v+P G ++++ef ++ + + ++ +v + D+ + + + + g vD +f D+ + sp|Q22053|FBRL_CAEEL 186 THIKPGTKLLYLGAASGTTVSHCSDVVGPEGIVYAVEFSHRSGRDLLG-VAKK--RPNVVPIVEDARhPHKY-RMLVGMVDVIFSDVAQ 270 579***************9999****************7644433333.3332..33444445566624555.5677************ PP GCD14 124 Pwea...iphaakalkkeggrlCsf.sPCieq 151 P++a +a + l++ g + s + Ci+ sp|Q22053|FBRL_CAEEL 271 PDQArivALNAQNFLRNGGHAVISIkANCIDS 302 **994322355666766655555542567765 PP >> tr|Q9N3T7|Q9N3T7_CAEEL Uncharacterized protein OS=Caenorhabditis elegans OX=6239 GN=CELE_Y47G6A.13 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 1.0 1.6e-05 0.078 103 232 .. 212 344 .. 196 412 .. 0.76 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 1.6e-05 GCD14 103 keGf.deevsgkvDavfLDlPaPweaiphaakal..kkeggrlCsfsPCieqvqrtceaLrelgfteietlevllrtyevrksklee 186 ++G d+ v v+L l Pw +++ ++ + kk+ l f + ++ e Lr l + + e ++ + ++l+ tr|Q9N3T7|Q9N3T7_CAEEL 212 EQGRcDDLVAMIYSIVYLTLGLPWSNLKDEKEIMsmKKSTKDLALFEDLPDELKSIFEYLRTLSYADRPNYEKIYNLLMAAITRLKI 298 55652333444456689**********999888764777788******************************999998888777776 PP GCD14 187 idlaekrleenerkriekakrrkaskdakvedkssksstevllkPv 232 l + e++e +r+ ka++++++k++k ++++++ ++e+ + + tr|Q9N3T7|Q9N3T7_CAEEL 299 NFLDPYEWEDDEMERMAKAEKEEKEKEEKEKKEKENKENELSADSM 344 6666666666666666666655555444444444443334333333 PP >> sp|Q27873|PIMT_CAEEL Protein-L-isoaspartate O-methyltransferase OS=Caenorhabditis elegans OX=6239 GN=pcm-1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 1.8e-05 0.091 37 93 .. 75 131 .. 64 181 .. 0.82 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 1.8e-05 GCD14 37 elkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsql 93 +l G+++++ G Gsg l+ +a v+ G + +e+ q +e + ++ r+h+ +ql sp|Q27873|PIMT_CAEEL 75 HLVAGAKALDVGSGSGYLTVCMAMMVGRNGTVVGIEHMPQLVELSEKNIRKHHSEQL 131 6889**********************************************9987553 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (247 nodes) Target sequences: 20008 (8229220 residues searched) Passed MSV filter: 1301 (0.065024); expected 400.2 (0.02) Passed bias filter: 826 (0.0412835); expected 400.2 (0.02) Passed Vit filter: 101 (0.00504798); expected 20.0 (0.001) Passed Fwd filter: 33 (0.00164934); expected 0.2 (1e-05) Initial search space (Z): 20008 [actual number of targets] Domain search space (domZ): 4 [number of targets reported over threshold] # CPU time: 0.38u 0.01s 00:00:00.39 Elapsed: 00:00:00.13 # Mc/sec: 15635.52 // [ok]