# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/GCD14.hmm.txt
# target sequence database:        proteomes/Ciona_savignyi.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       GCD14  [M=247]
Accession:   PF08704.9
Description: tRNA methyltransferase complex GCD14 subunit
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    3.5e-89  298.1   0.0    4.4e-89  297.8   0.0    1.1  1  tr|H2Z0U5|H2Z0U5_CIOSA  tRNA (adenine(58)-N(1))-methyltransfe
    1.1e-05   24.7   0.1    1.6e-05   24.1   0.1    1.2  1  tr|H2YFA0|H2YFA0_CIOSA  Uncharacterized protein OS=Ciona savi
  ------ inclusion threshold ------
          1    8.4   5.7         14    4.6   5.0    2.4  2  tr|H2YBX1|H2YBX1_CIOSA  Uncharacterized protein OS=Ciona savi
        4.4    6.3  11.5        1.1    8.3   4.2    2.0  2  tr|H2Y9H9|H2Y9H9_CIOSA  Uncharacterized protein OS=Ciona savi


Domain annotation for each sequence (and alignments):
>> tr|H2Z0U5|H2Z0U5_CIOSA  tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A OS=Ciona savignyi OX=5151
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  297.8   0.0   1.5e-92   4.4e-89       1     194 [.      62     255 ..      62     268 .. 0.95

  Alignments for each domain:
  == domain 1  score: 297.8 bits;  conditional E-value: 1.5e-92
                   GCD14   1 gfvyvlaptPeLWtlaLphrtqilytaDisliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefre 87 
                             g+vyvl+ptPeLWt++Lphrtqilyt Dis+i ++L+lkpGsvv+esGtGsgslshai+rt+aP G l+t+efhe raekar ef+e
  tr|H2Z0U5|H2Z0U5_CIOSA  62 GWVYVLQPTPELWTITLPHRTQILYTVDISMILFQLDLKPGSVVCESGTGSGSLSHAIIRTIAPSGYLHTVEFHEGRAEKARLEFKE 148
                             8************************************************************************************** PP

                   GCD14  88 helsqlvtvthrDvckeGfdeevsgkvDavfLDlPaPweaiphaakalkkeggrlCsfsPCieqvqrtceaLre..lgfteietlev 172
                             h+ls++vtv+hrDv k+Gf   v++++Da+fLD+P+P +ai  a++alkk+ggrlCsfsPCieqvqrtc aLr+  +gf +i+ +e+
  tr|H2Z0U5|H2Z0U5_CIOSA 149 HGLSNYVTVYHRDVLKDGF--PVTSVADAIFLDIPSPENAISTASNALKKSGGRLCSFSPCIEQVQRTCSALRQkgSGFRDIQIFEL 233
                             *******************..88999**********************************************983357********* PP

                   GCD14 173 llrtyevrkskleeidlaekrl 194
                               r  +v+++ ++++dl+ + +
  tr|H2Z0U5|H2Z0U5_CIOSA 234 VRRSSNVKRIFVPMADLGLADE 255
                             ***************9977654 PP

>> tr|H2YFA0|H2YFA0_CIOSA  Uncharacterized protein OS=Ciona savignyi OX=51511 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.1   0.1   5.5e-09   1.6e-05      35     150 ..     139     255 ..     133     272 .. 0.70

  Alignments for each domain:
  == domain 1  score: 24.1 bits;  conditional E-value: 5.5e-09
                   GCD14  35 kLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtvthrDvc.keGfdeevsgkvDavfLD 120
                              +++kpGs+v+  G+ sg+  + ++  v+P G ++++ef ++  +  + +  +++  +++ +   D+   + + + + g vD++f D
  tr|H2YFA0|H2YFA0_CIOSA 139 AIHIKPGSKVLYLGAASGTTVSHVSDIVGPEGLVYAVEFSHRSGRD-LINVAKKRT-NIIPI-IEDARhPHKY-RMLVGMVDTIFAD 221
                             5789***********************************7544433.333333332.33333.4455524555.5677********* PP

                   GCD14 121 lPaPwea..ip.haakalkkeggrlCsf.sPCie 150
                             + +P++   +  +a + lk+ g  + s  + Ci+
  tr|H2YFA0|H2YFA0_CIOSA 222 VAQPDQTriVAlNAHHFLKNAGHFVISIkASCID 255
                             ****986322214444556666655555245776 PP

>> tr|H2YBX1|H2YBX1_CIOSA  Uncharacterized protein OS=Ciona savignyi OX=51511 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    4.6   5.0     0.005        14     138     227 ..      12     101 ..       3     123 .. 0.67
   2 ?    1.4   0.0     0.046   1.3e+02      49      97 ..     158     206 ..     154     217 .. 0.85

  Alignments for each domain:
  == domain 1  score: 4.6 bits;  conditional E-value: 0.005
                   GCD14 138 eggrlCsfsPCieqvqrtceaLrelgfteietlevllrtyevrkskleeidl.aekrleenerkriekakrrkaskdakvedkssks 223
                             + ++  s s  ++ +q+ ++ L  ++  +i  +  ++ + ev ++ ++e+++  +++++en+  +++  ++++ s++ k + ++++ 
  tr|H2YBX1|H2YBX1_CIOSA  12 DRTKATSNSLIVDALQQVIKSLLTKDSDDIVKFRAQTEKLEVLQKAVKEMQMkVKAHQDENHLLKANVNEEKRRSDQYKHKLQKAQ- 97 
                             55667788889999*************************************94455555555555544444444444455555544. PP

                   GCD14 224 stev 227
                             ++ +
  tr|H2YBX1|H2YBX1_CIOSA  98 EALI 101
                             3333 PP

  == domain 2  score: 1.4 bits;  conditional E-value: 0.046
                   GCD14  49 tGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtvt 97 
                             t s s  h++++ +  + +l    f  +r +kar+e  +++++++ t++
  tr|H2YBX1|H2YBX1_CIOSA 158 TASISEDHSFTKPLPKRKRLSKTSFRSDRLKKARNERMSQDVKEIETIK 206
                             6677778999999999999999**************9999998877776 PP

>> tr|H2Y9H9|H2Y9H9_CIOSA  Uncharacterized protein OS=Ciona savignyi OX=51511 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    8.3   4.2   0.00037       1.1     164     229 ..       6      71 ..       1      87 [. 0.55
   2 ?    3.0   5.4     0.015        44     157     215 ..      57     117 ..      50     134 .. 0.60

  Alignments for each domain:
  == domain 1  score: 8.3 bits;  conditional E-value: 0.00037
                   GCD14 164 fteietlevllrtyevrkskleeidl.aekrleenerkriekakrrkaskdakvedkssksstevll 229
                              ++++t+e+ll+++++ k++l+      +k++ + ++kr + ak++ a  +++ ++++ + + e++ 
  tr|H2Y9H9|H2Y9H9_CIOSA   6 GQDLSTIEILLQKHKTEKKSLQAEIQaIKKAVPKGDKKREKIAKQKIADLENALKETHKQ-ELETVE 71 
                             589*************99999865551444444444444444444444333333333222.223332 PP

  == domain 2  score: 3.0 bits;  conditional E-value: 0.015
                   GCD14 157 eaLrelgfteietlevllrtyevrkskleeidlaekrleenerkr..iekakrrkaskdak 215
                             +aL+e++ +e+et+e  ++t ++  s+ +  + +e+  e+ ++++  +++++++ka+k ++
  tr|H2Y9H9|H2Y9H9_CIOSA  57 NALKETHKQELETVEKSQKTDAIDSSTTVLDNNGEEPSETRQKSKgkAKRKQEKKAMKAKE 117
                             6788999999999999888887777776666666555554433320022222233333333 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (247 nodes)
Target sequences:                        11592  (4231397 residues searched)
Passed MSV filter:                       678  (0.0584886); expected 231.8 (0.02)
Passed bias filter:                      402  (0.0346791); expected 231.8 (0.02)
Passed Vit filter:                        32  (0.00276052); expected 11.6 (0.001)
Passed Fwd filter:                         5  (0.000431332); expected 0.1 (1e-05)
Initial search space (Z):              11592  [actual number of targets]
Domain search space  (domZ):               4  [number of targets reported over threshold]
# CPU time: 0.13u 0.01s 00:00:00.14 Elapsed: 00:00:00.04
# Mc/sec: 26128.88
//
[ok]