# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/GCD14.hmm.txt
# target sequence database: proteomes/Danio_rerio.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: GCD14 [M=247]
Accession: PF08704.9
Description: tRNA methyltransferase complex GCD14 subunit
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
6.3e-104 347.5 0.0 8.4e-104 347.1 0.0 1.2 1 tr|F1QTY5|F1QTY5_DANRE tRNA (adenine(58)-N(1))-methyltransfe
6.8e-15 55.9 0.0 1.1e-14 55.2 0.0 1.3 1 tr|X1WF30|X1WF30_DANRE tRNA methyltransferase 61B OS=Danio r
3.3e-05 24.2 0.0 4.2e-05 23.8 0.0 1.1 1 sp|Q92047|PIMT_DANRE Protein-L-isoaspartate(D-aspartate) O
0.00011 22.5 0.0 0.00014 22.2 0.0 1.2 1 tr|F1QL05|F1QL05_DANRE Protein-L-isoaspartate O-methyltransf
0.00011 22.4 0.0 0.00017 21.9 0.0 1.2 1 tr|Q7ZTZ4|Q7ZTZ4_DANRE Fibrillarin OS=Danio rerio OX=7955 GN
0.0047 17.1 0.2 0.015 15.5 0.0 1.8 2 tr|F1QAE7|F1QAE7_DANRE Protein-L-isoaspartate (D-aspartate)
0.0088 16.3 0.0 0.013 15.7 0.0 1.2 1 tr|F1QJH5|F1QJH5_DANRE HemK methyltransferase family member
0.0093 16.2 0.2 0.023 14.9 0.0 1.7 2 tr|Q29R93|Q29R93_DANRE Protein-L-isoaspartate (D-aspartate)
------ inclusion threshold ------
0.022 14.9 0.0 0.039 14.1 0.0 1.3 1 tr|E7F846|E7F846_DANRE Protein-L-isoaspartate (D-aspartate)
0.17 12.0 0.0 0.27 11.4 0.0 1.3 1 tr|B8JIF1|B8JIF1_DANRE Arsenite methyltransferase OS=Danio r
0.3 11.2 0.0 0.42 10.8 0.0 1.1 1 sp|F4ZGF2|COMTA_DANRE Catechol O-methyltransferase A OS=Dan
Domain annotation for each sequence (and alignments):
>> tr|F1QTY5|F1QTY5_DANRE tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A OS=Danio rerio OX=7955 GN
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 347.1 0.0 3.6e-107 8.4e-104 1 246 [. 64 297 .. 64 298 .. 0.91
Alignments for each domain:
== domain 1 score: 347.1 bits; conditional E-value: 3.6e-107
GCD14 1 gfvyvlaptPeLWtlaLphrtqilytaDisliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefre 87
g+vyvl+ptPeLWt++Lphrtqilyt+Di+ i+ +LelkpGsvv+esGtGsgslsh+i+rt+aPtGhl+t+efh qraeka++ef+e
tr|F1QTY5|F1QTY5_DANRE 64 GWVYVLHPTPELWTINLPHRTQILYTTDIANITLMLELKPGSVVCESGTGSGSLSHSILRTIAPTGHLHTVEFHSQRAEKAMQEFKE 150
8************************************************************************************** PP
GCD14 88 helsqlvtvthrDvckeGfdeevsgkvDavfLDlPaPweaiphaakalkkeggrlCsfsPCieqvqrtceaLrelgfteietlevll 174
h++s+lvtv+++Dvck+Gf +++g++DavfLD+P+Pweai ha+kalk +ggrlCsfsPCieqvqrtceaL ++gf ei tlevll
tr|F1QTY5|F1QTY5_DANRE 151 HKVSHLVTVRNQDVCKDGF--GITGVADAVFLDIPSPWEAISHAKKALKYKGGRLCSFSPCIEQVQRTCEALLDHGFEEICTLEVLL 235
*******************..9***************************************************************** PP
GCD14 175 rtyevrkskleeidlaekrleenerkriekakrrkaskdakvedkssksstevllkPvselkghtgyLtfat 246
r+++vr+++l+ d + ++ +++++++++ ++ d +++ + P +e+ ghtgyLtf+
tr|F1QTY5|F1QTY5_DANRE 236 RVHDVRTVTLPLPDFGPEEYYADSTQTTSDISQE---------DVNTS-VICRTATPPREMAGHTGYLTFSS 297
***************9887777766633333222.........22222.222234588************86 PP
>> tr|X1WF30|X1WF30_DANRE tRNA methyltransferase 61B OS=Danio rerio OX=7955 GN=trmt61b PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 55.2 0.0 4.9e-18 1.1e-14 22 243 .. 214 443 .. 200 447 .. 0.72
Alignments for each domain:
== domain 1 score: 55.2 bits; conditional E-value: 4.9e-18
GCD14 22 qilytaDisliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehel..........sqlvtvth 98
i y +D s + +++++++G v+e G Gsg +s ++r+v+ +G + ++e e+ ++++ ++++ ++v+ +h
tr|X1WF30|X1WF30_DANRE 214 AIAYPKDASAMLTMMDVTEGDCVLECGSGSGGMSLFLSRAVGYKGSVLSVEIREDHHKRSVLNYQRWLNtwrrrggqewPDNVHFHH 300
689***********************************************98666555554444432111223333444679***** PP
GCD14 99 rDvckeGfdeevsgkvDavfLDlPaPweaiphaakalkkeggrlCsfsPCieqvqrtceaLrelgftei..etlevllrtyevrksk 183
D+ + G ++v LD+ +P a+p ++ l + g++ + i qv eaLr + + ev+ r + v s
tr|X1WF30|X1WF30_DANRE 301 GDIISAGT-LLAGRGLNSVALDMINPHLALPVVVPYL-HPGSVCAVYQANITQVIDLLEALRCSALPLVceCITEVQHRDWLVVPS- 384
*******8.2333578*********************.67777778999*************9886544213469****9988654. PP
GCD14 184 leeidlaekrl...eenerkriekakrrkaskdakvedkssksstevllkPvselkghtgyLt 243
l++ ++kr+ e+ ++++++ + ++ +++++v + + + +++P e +ght++L+
tr|X1WF30|X1WF30_DANRE 385 LKKDGTFNKRKapyENGDQDEPSLKTEEVLNSQDAVPFG----DVQYIARPHPEQVGHTAFLV 443
333333333220002222332222222223333344443....45699*************96 PP
>> sp|Q92047|PIMT_DANRE Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Danio rerio OX=7955 GN=pcmt PE=2 SV=
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 23.8 0.0 1.8e-08 4.2e-05 37 100 .. 75 138 .. 55 181 .. 0.75
Alignments for each domain:
== domain 1 score: 23.8 bits; conditional E-value: 1.8e-08
GCD14 37 elkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtvthrD 100
+l +G+++++ G Gsg ls ++r v+PtG++ +++ ++ +e ++ + ++++ s ++ + +
sp|Q92047|PIMT_DANRE 75 HLYEGAKALDVGSGSGILSVCFSRMVGPTGKVIGIDHIKELVEDSIANVKKDDPSLITSGRIKL 138
5679************************************999999999988754444333333 PP
>> tr|F1QL05|F1QL05_DANRE Protein-L-isoaspartate O-methyltransferase OS=Danio rerio OX=7955 GN=pcmtl PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 22.2 0.0 5.8e-08 0.00014 37 95 .. 96 154 .. 76 200 .. 0.80
Alignments for each domain:
== domain 1 score: 22.2 bits; conditional E-value: 5.8e-08
GCD14 37 elkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvt 95
+l++G+ +++ G Gsg l+ +ar v+P G++ +++ +q +++++++ + ++ + l t
tr|F1QL05|F1QL05_DANRE 96 KLTEGASALDVGSGSGYLTACFARMVGPSGKVVGIDHIDQLVQSSVKNVQADDPELLAT 154
789*****************************************999988776555544 PP
>> tr|Q7ZTZ4|Q7ZTZ4_DANRE Fibrillarin OS=Danio rerio OX=7955 GN=fbl PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 21.9 0.0 7.2e-08 0.00017 34 149 .. 149 265 .. 141 282 .. 0.71
Alignments for each domain:
== domain 1 score: 21.9 bits; conditional E-value: 7.2e-08
GCD14 34 mkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtvthrDvc.keGfdeevsgkvDavfL 119
++++kpG +v+ G+ sg+ + ++ v+P G ++++ef ++ + + + +++ ++ D+ + + + + g vD +f
tr|Q7ZTZ4|Q7ZTZ4_DANRE 149 DQIHIKPGVKVMYLGAASGTTVSHVSDIVGPEGLVYAVEFSHRSGRD-LLNVAKKR--TNIIPIIEDARhPHKY-RMLVGMVDVIFA 231
5789************************************7644433.33333333..3333334455524555.5677******** PP
GCD14 120 DlPaPwea..i.phaakalkkeggrlCsf.sPCi 149
D+ +P++ + +a + lk+ g + s + Ci
tr|Q7ZTZ4|Q7ZTZ4_DANRE 232 DVAQPDQTriVaLNAHNFLKNGGHFVISIkANCI 265
*****98632213555666555554444424566 PP
>> tr|F1QAE7|F1QAE7_DANRE Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain-containing 1 OS=Danio rerio O
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 15.5 0.0 6.5e-06 0.015 30 84 .. 70 124 .. 60 135 .. 0.90
2 ? -1.3 0.2 0.88 2.1e+03 166 209 .. 239 280 .. 200 336 .. 0.52
Alignments for each domain:
== domain 1 score: 15.5 bits; conditional E-value: 6.5e-06
GCD14 30 sliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekaree 84
s ++ L+l++G ++ G G+g ls+ + ++P G + +e h++ +e a e
tr|F1QAE7|F1QAE7_DANRE 70 SEVMEALKLQQGLSFLNLGSGTGYLSTMVGLIIGPFGVNHGVELHKDVVEYANER 124
568899****************************************999988764 PP
== domain 2 score: -1.3 bits; conditional E-value: 0.88
GCD14 166 eietlevllrtyevrkskleeidlaekrleenerkriekakrrk 209
+++l+ l r y r+ + ++ +r+++ ++ +k+krr+
tr|F1QAE7|F1QAE7_DANRE 239 SVRSLQDLSRIYIRRTLSSLINEENPNRTNTP--RASQKRKRRR 280
44555555555554443322222222222111..1122222222 PP
>> tr|F1QJH5|F1QJH5_DANRE HemK methyltransferase family member 1 OS=Danio rerio OX=7955 GN=hemk1 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 15.7 0.0 5.6e-06 0.013 44 104 .. 166 225 .. 150 243 .. 0.91
Alignments for each domain:
== domain 1 score: 15.7 bits; conditional E-value: 5.6e-06
GCD14 44 vvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtvthrDvcke 104
+e G Gsg++s +++r++ P+ ++f+++ ++ + +e+ ++ +l++ + v+h Dv k+
tr|F1QJH5|F1QJH5_DANRE 166 GLEVGCGSGAISLSLLRSL-PQLRVFALDQSQDAVCLTMENANRLGLQDRLEVHHLDVVKD 225
589***************8.999***********************************987 PP
>> tr|Q29R93|Q29R93_DANRE Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain-containing 2 OS=Danio rerio O
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 14.9 0.0 9.7e-06 0.023 30 84 .. 70 124 .. 61 147 .. 0.90
2 ? -2.9 0.2 2.6 6.1e+03 195 222 .. 313 340 .. 303 354 .. 0.41
Alignments for each domain:
== domain 1 score: 14.9 bits; conditional E-value: 9.7e-06
GCD14 30 sliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekaree 84
s ++ L+l+pG ++ G G+g ls+ + ++P G + +e he+ +e a ++
tr|Q29R93|Q29R93_DANRE 70 SEVMEALDLQPGLSFLNLGSGTGYLSTMVGLILGPFGVNHGVELHEDVIEYAYQK 124
568899*****************************************99999875 PP
== domain 2 score: -2.9 bits; conditional E-value: 2.6
GCD14 195 eenerkriekakrrkaskdakvedkssk 222
++++++ e+ +r ++++ ++++ +
tr|Q29R93|Q29R93_DANRE 313 STDNEDEDEDLRRVCELEEKEENERRKE 340
2333332333333333333333333333 PP
>> tr|E7F846|E7F846_DANRE Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 OS=Danio rerio O
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 14.1 0.0 1.7e-05 0.039 30 84 .. 70 124 .. 63 132 .. 0.92
Alignments for each domain:
== domain 1 score: 14.1 bits; conditional E-value: 1.7e-05
GCD14 30 sliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekaree 84
s ++ L+l+pG ++ G G+g ls+ + ++P G + +e h++ ++ a ++
tr|E7F846|E7F846_DANRE 70 SEVMEALDLQPGLSFLNLGSGTGYLSTMVGLILGPFGVNHGVELHKDVVDYAYQK 124
567889*****************************************99999875 PP
>> tr|B8JIF1|B8JIF1_DANRE Arsenite methyltransferase OS=Danio rerio OX=7955 GN=as3mt PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.4 0.0 0.00012 0.27 39 85 .. 73 119 .. 67 156 .. 0.89
Alignments for each domain:
== domain 1 score: 11.4 bits; conditional E-value: 0.00012
GCD14 39 kpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareef 85
+G++v++ G Gsg +++ v+ +Gh+ ++ e++ e ar+
tr|B8JIF1|B8JIF1_DANRE 73 LEGCRVLDLGCGSGRDCYMLSQLVGEKGHVTGIDMTEAQLEVARNYI 119
68***************************************999754 PP
>> sp|F4ZGF2|COMTA_DANRE Catechol O-methyltransferase A OS=Danio rerio OX=7955 GN=comta PE=1 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 10.8 0.0 0.00018 0.42 41 120 .. 101 183 .. 90 191 .. 0.77
Alignments for each domain:
== domain 1 score: 10.8 bits; conditional E-value: 0.00018
GCD14 41 GsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsq.lvtvt..hrDvckeGf.deevsgkvDavfLD 120
s ++e Gt g + iar ++P +l t+ef + a ar+ +l++ ++ v+ D+ + ++++ ++ D vfLD
sp|F4ZGF2|COMTA_DANRE 101 PSTALELGTYCGYSTVRIARLLSPGTKLITLEFNPDYAAIARQIIAYAGLQDkVILVEgpSGDLIPKMKqQHGI-KSFDFVFLD 183
46789**************************************9999999773444442245665333314445.667777776 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (247 nodes)
Target sequences: 25687 (13798380 residues searched)
Passed MSV filter: 1807 (0.0703469); expected 513.7 (0.02)
Passed bias filter: 1080 (0.0420446); expected 513.7 (0.02)
Passed Vit filter: 107 (0.00416553); expected 25.7 (0.001)
Passed Fwd filter: 26 (0.00101219); expected 0.3 (1e-05)
Initial search space (Z): 25687 [actual number of targets]
Domain search space (domZ): 11 [number of targets reported over threshold]
# CPU time: 0.50u 0.01s 00:00:00.51 Elapsed: 00:00:00.14
# Mc/sec: 24344.28
//
[ok]