# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/GCD14.hmm.txt
# target sequence database:        proteomes/Drosophila_melanogaster.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       GCD14  [M=247]
Accession:   PF08704.9
Description: tRNA methyltransferase complex GCD14 subunit
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
     4e-107  357.1   0.0   5.1e-107  356.8   0.0    1.1  1  tr|Q9VBH7|Q9VBH7_DROME  tRNA (adenine(58)-N(1))-methyltransfe
    9.4e-05   21.8   0.0    0.00014   21.3   0.0    1.2  1  sp|Q9W1V3|FBRL_DROME    rRNA 2'-O-methyltransferase fibrillar


Domain annotation for each sequence (and alignments):
>> tr|Q9VBH7|Q9VBH7_DROME  tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A OS=Drosophila melanogaste
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  356.8   0.0  7.4e-111  5.1e-107       1     246 [.      72     309 ..      72     310 .. 0.99

  Alignments for each domain:
  == domain 1  score: 356.8 bits;  conditional E-value: 7.4e-111
                   GCD14   1 gfvyvlaptPeLWtlaLphrtqilytaDisliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefre 87 
                             g+++vl+ptPeLWt++Lphrtqi+yt+Dis+ii++Le++pG+vvvesGtGsgslsh+++r+++PtGhl+tf+fhe+ra++ar+efr+
  tr|Q9VBH7|Q9VBH7_DROME  72 GWAHVLQPTPELWTQTLPHRTQIIYTPDISMIIHQLEVRPGAVVVESGTGSGSLSHYFLRALKPTGHLHTFDFHEARADQARDEFRR 158
                             8************************************************************************************** PP

                   GCD14  88 helsqlvtvthrDvckeGfdeevsgkvDavfLDlPaPweaiphaakalkkeggrlCsfsPCieqvqrtceaLrelgfteietlevll 174
                             h+++++vtv+hrDvc+ Gf +e++gk+DavfLDlPaP+ a+pha+kalk +ggr+CsfsPCieq qr++++L++lgf+ei +levl+
  tr|Q9VBH7|Q9VBH7_DROME 159 HGIADFVTVYHRDVCNLGFGAELDGKADAVFLDLPAPDLAVPHAFKALKLSGGRFCSFSPCIEQSQRCIQELTKLGFNEIVSLEVLQ 245
                             *************************************************************************************** PP

                   GCD14 175 rtyevrkskleeidl.aekrleenerkriekakrrkaskdakvedkssksstevllkPvselkghtgyLtfat 246
                             +++ v++++l++idl + k  +++e++++++a ++ka k+ k++ +ss+        P ++l ghtg+Ltfat
  tr|Q9VBH7|Q9VBH7_DROME 246 QENVVKTRTLPVIDLeFLKLPKTDETTAATNALESKAPKEVKKYLTSSN--------P-QTLPGHTGFLTFAT 309
                             ***************999*******************************........7.99***********8 PP

>> sp|Q9W1V3|FBRL_DROME  rRNA 2'-O-methyltransferase fibrillarin OS=Drosophila melanogaster OX=7227 GN=Fib PE=2 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   21.3   0.0     2e-08   0.00014      35     150 ..     179     295 ..     173     313 .. 0.68

  Alignments for each domain:
  == domain 1  score: 21.3 bits;  conditional E-value: 2e-08
                 GCD14  35 kLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtvthrDvc.keGfdeevsgkvDavfLDlP 122
                           ++++ pGs+v+  G+ sg+  + ++  v+P G ++++ef ++  +  + +  +++  +++ +   D+   + + + + g vD++f D+ 
  sp|Q9W1V3|FBRL_DROME 179 QIHMPPGSKVLYLGAASGTTVSHVSDVVGPEGLVYAVEFSHRSGRD-LINVAKKRT-NIIPI-IEDARhPHKY-RMLVGMVDTIFADVA 263
                           67889**********************************7544433.333333332.33333.4455524555.5677*********** PP

                 GCD14 123 aPwea..ip.haakalkkeggrlCsf.sPCie 150
                           +P++   +  +a + lk+ g  + s  + Ci+
  sp|Q9W1V3|FBRL_DROME 264 QPDQGriVAlNAQHFLKNGGHFVISIkASCID 295
                           **985223313333344444444443245665 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (247 nodes)
Target sequences:                        13786  (7394964 residues searched)
Passed MSV filter:                      1089  (0.0789932); expected 275.7 (0.02)
Passed bias filter:                      610  (0.0442478); expected 275.7 (0.02)
Passed Vit filter:                        50  (0.00362687); expected 13.8 (0.001)
Passed Fwd filter:                         8  (0.000580299); expected 0.1 (1e-05)
Initial search space (Z):              13786  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.25u 0.01s 00:00:00.26 Elapsed: 00:00:00.08
# Mc/sec: 22831.95
//
[ok]