# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/GCD14.hmm.txt
# target sequence database: proteomes/Macaca_mulatta.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: GCD14 [M=247]
Accession: PF08704.9
Description: tRNA methyltransferase complex GCD14 subunit
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
1.5e-104 349.3 0.2 9.7e-100 333.5 0.0 2.1 2 tr|F7D5P9|F7D5P9_MACMU tRNA (adenine(58)-N(1))-methyltr
5.3e-18 65.8 0.0 7.5e-18 65.3 0.0 1.1 1 tr|F7D1K5|F7D1K5_MACMU tRNA methyltransferase 61B OS=Ma
0.00019 21.4 0.0 0.00028 20.9 0.0 1.2 1 tr|A0A1D5RDW4|A0A1D5RDW4_MACMU Fibrillarin OS=Macaca mulatta OX
0.0013 18.7 0.0 0.0018 18.2 0.0 1.2 1 tr|F7GFV2|F7GFV2_MACMU Protein-L-isoaspartate O-methylt
0.0021 18.0 0.0 0.003 17.5 0.0 1.2 1 tr|F7ED78|F7ED78_MACMU Fibrillarin like 1 OS=Macaca mul
0.0045 16.9 0.0 0.018 14.9 0.0 1.8 2 tr|F7EGP9|F7EGP9_MACMU Protein-L-isoaspartate (D-aspart
------ inclusion threshold ------
0.017 15.1 0.0 0.03 14.2 0.0 1.4 1 tr|F7D8R1|F7D8R1_MACMU Protein-L-isoaspartate (D-aspart
4.6 7.1 6.4 7.2 6.5 4.9 1.8 2 tr|A0A1D5Q784|A0A1D5Q784_MACMU Biogenesis of lysosome-related o
Domain annotation for each sequence (and alignments):
>> tr|F7D5P9|F7D5P9_MACMU tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A OS=Macaca mulatta OX=9544
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 333.5 0.0 3.7e-103 9.7e-100 1 189 [. 64 250 .. 64 263 .. 0.98
2 ! 14.1 0.1 1.2e-05 0.033 230 247 .] 265 282 .. 261 282 .. 0.91
Alignments for each domain:
== domain 1 score: 333.5 bits; conditional E-value: 3.7e-103
GCD14 1 gfvyvlaptPeLWtlaLphrtqilytaDisliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefre 87
g+vyvl+ptPeLWtl+Lphrtqily++Di+li+m+Lel+pGsvv+esGtGsgs+shai+rt+aPtGhl+t+efh+qraekareef+e
tr|F7D5P9|F7D5P9_MACMU 64 GWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHAIIRTIAPTGHLHTVEFHQQRAEKAREEFQE 150
8************************************************************************************** PP
GCD14 88 helsqlvtvthrDvckeGfdeevsgkvDavfLDlPaPweaiphaakalkkeggrlCsfsPCieqvqrtceaLrelgfteietlevll 174
h++ +vtv+++Dvc++Gf +vs+++DavfLD+P+Pwea++ha++alk eggr+CsfsPCieqvqrtc+aL++ gf e++tlevl
tr|F7D5P9|F7D5P9_MACMU 151 HRVGRWVTVRTQDVCRSGF--GVSHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLP 235
*******************..9***************************************************************** PP
GCD14 175 rtyevrkskleeidl 189
++y+vr+++l+ dl
tr|F7D5P9|F7D5P9_MACMU 236 QVYNVRTVSLPPPDL 250
**********98887 PP
== domain 2 score: 14.1 bits; conditional E-value: 1.2e-05
GCD14 230 kPvselkghtgyLtfatk 247
P++e++ghtgyLtfatk
tr|F7D5P9|F7D5P9_MACMU 265 TPMKEAVGHTGYLTFATK 282
69**************86 PP
>> tr|F7D1K5|F7D1K5_MACMU tRNA methyltransferase 61B OS=Macaca mulatta OX=9544 GN=TRMT61B PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 65.3 0.0 2.8e-21 7.5e-18 14 243 .. 220 467 .. 210 471 .. 0.75
Alignments for each domain:
== domain 1 score: 65.3 bits; conditional E-value: 2.8e-21
GCD14 14 tlaLphrtqilytaDisliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehel.......... 90
l ++ t + +Dis+i ++++ pG v+e+G Gsg +s ++++v+ +G++ +fe ++ + a++++++ +
tr|F7D1K5|F7D1K5_MACMU 220 VLLMKRGTAVTVPKDISMILLMMDISPGDTVLEAGSGSGGMSLFLSKAVGSQGRVISFEVRKDHHDLAKKNYKHWRDswklshveew 306
55566668888899**********************************************999999999998865432333555554 PP
GCD14 91 sqlvtvthrDvckeGfdeevsg.kvDavfLDlPaPweaiphaakalkkeggrlCsfsPCieqvqrtceaLr..elgfteietlevll 174
++v h+D+ G +e+++ + Dav LD+ +P +p l k+gg+ + i qv + + +r el + ev +
tr|F7D1K5|F7D1K5_MACMU 307 PDNVDFIHKDIS--GATEDIKAlTFDAVALDMLNPHITLPVFYPRL-KHGGVCAVYLANITQVIELLDGIRicELALSCEKISEVTV 390
568999999996..55567765268*********************.6677777788889998877766551133444446679*** PP
GCD14 175 rtyevrkskleeidlaekrleenerkriekakrrka.skdakvedkssks.......stevllkPvselkghtgyLt 243
+ + v k ++ la+k + + + + + +++ +++ +ed +++s s +++Pv+ +ght++L+
tr|F7D1K5|F7D1K5_MACMU 391 KDWLVCLAKRKTGILAQKVEPKINIDVQLDSQKKTGvEDELFQEDDREEShsdfpygSFPYVARPVHWQHGHTAFLV 467
****999998888888777766665544444444332333333333333355668888899**************96 PP
>> tr|A0A1D5RDW4|A0A1D5RDW4_MACMU Fibrillarin OS=Macaca mulatta OX=9544 GN=FBL PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 20.9 0.0 1e-07 0.00028 35 150 .. 155 271 .. 147 297 .. 0.69
Alignments for each domain:
== domain 1 score: 20.9 bits; conditional E-value: 1e-07
GCD14 35 kLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtvthrDvckeGfdeevsgk 113
++++kpG++v+ G+ sg+ + ++ v+P G ++++ef + r + + ++ +++ ++++ v + + ++ +
tr|A0A1D5RDW4|A0A1D5RDW4_MACMU 155 QIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSH-RSGRDLINLAKKR-TNIIPVIEDARHPHKYR-MLIAM 230
789************************************65.4444455555444.34455544334456664.55599 PP
GCD14 114 vDavfLDlPaPwea.ip..haakalkkeggrlCsf.sPCie 150
vD +f D+ +P++ i +a + l++ g + s + Ci+
tr|A0A1D5RDW4|A0A1D5RDW4_MACMU 231 VDVIFADVAQPDQTrIValNAHTFLRNGGHFVISIkANCID 271
***********986332013333344444333443245665 PP
>> tr|F7GFV2|F7GFV2_MACMU Protein-L-isoaspartate O-methyltransferase OS=Macaca mulatta OX=9544 GN=PCMT1 PE=3 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 18.2 0.0 6.8e-07 0.0018 37 90 .. 98 151 .. 87 203 .. 0.81
Alignments for each domain:
== domain 1 score: 18.2 bits; conditional E-value: 6.8e-07
GCD14 37 elkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehel 90
+l++G+++++ G Gsg l+ +ar v+ tG++ +++ ++ ++ ++++ r+++
tr|F7GFV2|F7GFV2_MACMU 98 QLHEGAKALDVGSGSGILTACFARMVGCTGKVIGIDHIKELVDDSINNVRKDDP 151
5789***************************************99999998764 PP
>> tr|F7ED78|F7ED78_MACMU Fibrillarin like 1 OS=Macaca mulatta OX=9544 GN=FBLL1 PE=3 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 17.5 0.0 1.1e-06 0.003 35 150 .. 131 247 .. 121 272 .. 0.71
Alignments for each domain:
== domain 1 score: 17.5 bits; conditional E-value: 1.1e-06
GCD14 35 kLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtvthrDvc.keGfdeevsgkvDavfLD 120
++++kp s+v+ G+ sg+ + ++ ++P G ++++ef +ra + + + +++ +++ v D+ + + + g vD +f D
tr|F7ED78|F7ED78_MACMU 131 QIHIKPKSKVLYLGAASGTTVSHVSDIIGPDGLVYAVEFS-HRAGRDLVNVAKKRT-NIIPVL-EDARhPLKY-RMLIGMVDVIFAD 213
7899****************99*****************6.466666666665553.344444.444414445.5566********* PP
GCD14 121 lPaPwea.ip..haakalkkeggrlCsf.sPCie 150
+ +P+++ i +a + l++ g l s + Ci+
tr|F7ED78|F7ED78_MACMU 214 VAQPDQSrIValNAHTFLRNGGHFLISIkANCID 247
****986332113334455555555554245665 PP
>> tr|F7EGP9|F7EGP9_MACMU Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 OS=Macaca mulatt
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 14.9 0.0 6.9e-06 0.018 30 86 .. 70 126 .. 60 141 .. 0.92
2 ? -1.0 0.0 0.51 1.4e+03 206 227 .. 304 325 .. 281 354 .. 0.54
Alignments for each domain:
== domain 1 score: 14.9 bits; conditional E-value: 6.9e-06
GCD14 30 sliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefr 86
s ++ L+l+pG ++ G G+g ls+ + ++P G + +e h + +e a+e+++
tr|F7EGP9|F7EGP9_MACMU 70 SEVMEALKLQPGLSFLNLGSGTGYLSTMVGLILGPFGINHGIELHSDVVEYAKEKLE 126
568899******************************************999998765 PP
== domain 2 score: -1.0 bits; conditional E-value: 0.51
GCD14 206 krrkaskdakvedkssksstev 227
+ +k+++d+k e+++++s++
tr|F7EGP9|F7EGP9_MACMU 304 EDEKMEEDNKEEEEKDHSEAMK 325
3333444444333333332222 PP
>> tr|F7D8R1|F7D8R1_MACMU Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 OS=Macaca mulatt
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 14.2 0.0 1.1e-05 0.03 30 84 .. 70 124 .. 54 147 .. 0.91
Alignments for each domain:
== domain 1 score: 14.2 bits; conditional E-value: 1.1e-05
GCD14 30 sliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekaree 84
s ++ L+l+pG ++ G G+g ls+ + ++P G + +e h + +e a+++
tr|F7D8R1|F7D8R1_MACMU 70 SEVMEALDLQPGLSFLNLGSGTGYLSSMVGLILGPFGVNHGVELHSDVIEYAKQK 124
568899*****************************************99999885 PP
>> tr|A0A1D5Q784|A0A1D5Q784_MACMU Biogenesis of lysosome-related organelles complex 1 subunit 6 OS=Macaca mulatta OX=95
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 0.8 0.0 0.14 3.7e+02 148 172 .. 63 87 .. 41 99 .. 0.55
2 ? 6.5 4.9 0.0027 7.2 162 233 .. 96 170 .. 83 172 .] 0.69
Alignments for each domain:
== domain 1 score: 0.8 bits; conditional E-value: 0.14
GCD14 148 CieqvqrtceaLrelgfteietlev 172
+++ +++ ++L++ + + ++tle
tr|A0A1D5Q784|A0A1D5Q784_MACMU 63 DLQRSKQALQELTQNQVVLLDTLEQ 87
4433444444444444444444443 PP
== domain 2 score: 6.5 bits; conditional E-value: 0.0027
GCD14 162 lgfteietlevllrtyevrkskleeidlaekrleenerkriekakrrkaskdakvedkssks...stevllkPvs 233
+ +i++l ++y+++ +++++ l+ +++ ++ +kr+ k ++++++++ + e++++k ++++ ++P +
tr|A0A1D5Q784|A0A1D5Q784_MACMU 96 HSMLDINALFAEAKHYHAKLVNIRKEMLMLHEKTSKLKKRALKLQQKRQKEELEREQQREKEferEKQLTARPAK 170
67889******************9988866666666566666666666655555555554433546677888865 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (247 nodes)
Target sequences: 21211 (10888574 residues searched)
Passed MSV filter: 1170 (0.0551601); expected 424.2 (0.02)
Passed bias filter: 796 (0.0375277); expected 424.2 (0.02)
Passed Vit filter: 77 (0.00363019); expected 21.2 (0.001)
Passed Fwd filter: 17 (0.000801471); expected 0.2 (1e-05)
Initial search space (Z): 21211 [actual number of targets]
Domain search space (domZ): 8 [number of targets reported over threshold]
# CPU time: 0.35u 0.01s 00:00:00.36 Elapsed: 00:00:00.13
# Mc/sec: 20688.29
//
[ok]