# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/GCD14.hmm.txt
# target sequence database: proteomes/Monodelphis_domestica.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: GCD14 [M=247]
Accession: PF08704.9
Description: tRNA methyltransferase complex GCD14 subunit
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
6.4e-104 347.2 0.5 1.9e-99 332.6 0.2 2.1 2 tr|F7F8B1|F7F8B1_MONDO tRNA (adenine(58)-N(1))-methyltransfe
1.4e-15 57.9 0.0 1.9e-15 57.5 0.0 1.2 1 tr|K7E169|K7E169_MONDO Uncharacterized protein OS=Monodelphi
9.4e-05 22.5 0.0 0.00013 21.9 0.0 1.2 1 tr|F6YAE8|F6YAE8_MONDO Fibrillarin OS=Monodelphis domestica
0.0034 17.4 0.0 0.0047 16.9 0.0 1.1 1 tr|H9H7D7|H9H7D7_MONDO Uncharacterized protein OS=Monodelphi
0.0043 17.0 0.0 0.0056 16.6 0.0 1.2 1 tr|F7FVJ3|F7FVJ3_MONDO Protein-L-isoaspartate O-methyltransf
------ inclusion threshold ------
0.017 15.1 0.0 0.038 13.9 0.0 1.5 1 tr|F6VKL8|F6VKL8_MONDO Protein-L-isoaspartate (D-aspartate)
0.046 13.6 0.1 0.1 12.5 0.0 1.5 2 tr|F6QTB4|F6QTB4_MONDO Protein-L-isoaspartate (D-aspartate)
Domain annotation for each sequence (and alignments):
>> tr|F7F8B1|F7F8B1_MONDO tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A OS=Monodelphis domestica
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 332.6 0.2 6.2e-103 1.9e-99 1 189 [. 192 378 .. 192 383 .. 0.98
2 ! 12.9 0.0 2.5e-05 0.075 228 246 .. 395 413 .. 388 414 .. 0.85
Alignments for each domain:
== domain 1 score: 332.6 bits; conditional E-value: 6.2e-103
GCD14 1 gfvyvlaptPeLWtlaLphrtqilytaDisliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefre 87
g+vyvl+ptPeLWtl+Lphrtqily++Dis+i+m+LelkpGs v+esGtGsgslshai+rtvaPtGhl+t+efh+qra+ka eefre
tr|F7F8B1|F7F8B1_MONDO 192 GWVYVLHPTPELWTLNLPHRTQILYSTDISIITMMLELKPGSIVCESGTGSGSLSHAIIRTVAPTGHLHTVEFHQQRAQKAEEEFRE 278
8************************************************************************************** PP
GCD14 88 helsqlvtvthrDvckeGfdeevsgkvDavfLDlPaPweaiphaakalkkeggrlCsfsPCieqvqrtceaLrelgfteietlevll 174
h+++ +vtv+++Dvck+Gf +vs+++DavfLD+P+Pweai+ha++alk eggrlCsfsPCieqvqrtc+ L+e+gf+e++tl +ll
tr|F7F8B1|F7F8B1_MONDO 279 HRVDRWVTVRNQDVCKNGF--GVSHVADAVFLDIPSPWEAIGHAKDALKVEGGRLCSFSPCIEQVQRTCHDLTEHGFIEVTTLKILL 363
*******************..9***************************************************************** PP
GCD14 175 rtyevrkskleeidl 189
r+y+vr+s+l++ l
tr|F7F8B1|F7F8B1_MONDO 364 RKYNVRTSHLPMQHL 378
********9988766 PP
== domain 2 score: 12.9 bits; conditional E-value: 2.5e-05
GCD14 228 llkPvselkghtgyLtfat 246
++ P++e++ghtgyLtfa
tr|F7F8B1|F7F8B1_MONDO 395 IAVPLKETVGHTGYLTFAS 413
678**************97 PP
>> tr|K7E169|K7E169_MONDO Uncharacterized protein OS=Monodelphis domestica OX=13616 GN=TRMT61B PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 57.5 0.0 6.2e-19 1.9e-15 18 243 .. 251 497 .. 234 501 .. 0.75
Alignments for each domain:
== domain 1 score: 57.5 bits; conditional E-value: 6.2e-19
GCD14 18 phrtqilytaDisliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehel..........sqlv 94
+ i y +D+ ++ m++++k+G v+++ G Gsg +s ++++v+ +G++ +fe ++ ++a+++++ + ++v
tr|K7E169|K7E169_MONDO 251 KRGPTISYPKDMNMMLMMMNIKQGDVILDVGSGSGGMSLFLSQAVGVRGQVKSFEIRKDHHNQAKKNYKCWRDawkishveewPNNV 337
4445799*************************************************9999999999987432222235545445689 PP
GCD14 95 tvthrDvckeGfdeevsg.kvDavfLDlPaPweaiphaakalkkeggrlCsfsPCieqvqrtceaLr..elgfteietlevllrtye 178
h+D+ + ++++ D v LD+ +P a+p + l k+gg+ + i qv + e +r el + +evllr +
tr|K7E169|K7E169_MONDO 338 DFIHKDILEAAE--DIESiIFDGVALDMLNPQIALPIVYPNL-KQGGVCAVYLANITQVIELLEGIRicELSLSCEQIIEVLLRDWL 421
9999**998766..5544167*********************.78888888999999998888766522455555689********* PP
GCD14 179 vrkskleeidlaekrleenerk.riekakrrkaskdakvedkssks..........stevllkPv..selkghtgyLt 243
v k + la++ + +++ + + + ++++++++++++++++ s +++P+ + ht++L+
tr|K7E169|K7E169_MONDO 422 VCPAKRKDGTLAQRVQPKVSVDlKLHSQREIETEESENIQEND--YgeslpgfpysSIPYIARPFhyQANYNHTAFLV 497
*999999999988877777655133333444444444444444..333588888866777888875556678999986 PP
>> tr|F6YAE8|F6YAE8_MONDO Fibrillarin OS=Monodelphis domestica OX=13616 GN=FBL PE=3 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 21.9 0.0 4.4e-08 0.00013 35 141 .. 153 259 .. 144 291 .. 0.71
Alignments for each domain:
== domain 1 score: 21.9 bits; conditional E-value: 4.4e-08
GCD14 35 kLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtvthrDvc.keGfdeevsgkvDavfLD 120
+++++pG++v+ G+ sg+ + ++ v+P G ++++ef ++ + + + +++ ++++ v + D+ + + + + g vD +f D
tr|F6YAE8|F6YAE8_MONDO 153 QIHIRPGAKVLYLGAASGTTVSHVSDIVGPEGLVYAVEFSHRSGRD-LINVAKKR-TNIIPVIE-DARhPHKY-RMLIGMVDVIFAD 235
789************************************7544433.33443333.34455544.54415666.5566********* PP
GCD14 121 lPaPwea..i.phaakalkkeggr 141
+ +P+++ + +a + l++ g
tr|F6YAE8|F6YAE8_MONDO 236 VAQPDQSriVaLNAHNFLRNGGHF 259
****98632212445555444444 PP
>> tr|H9H7D7|H9H7D7_MONDO Uncharacterized protein OS=Monodelphis domestica OX=13616 PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 16.9 0.0 1.5e-06 0.0047 41 120 .. 105 187 .. 86 197 .. 0.80
Alignments for each domain:
== domain 1 score: 16.9 bits; conditional E-value: 1.5e-06
GCD14 41 GsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtv...thrDvckeGf.deevsgkvDavfLD 120
v +e Gt g + +ar + P +lft+ef e+ a+ a + + +l++ + + +++++ + ++e+ ++vD vfLD
tr|H9H7D7|H9H7D7_MONDO 105 PRVLLELGTYCGYSAIRMARLLPPGARLFTIEFNESFASIASQMIQLAGLQDKISIlkgSTQEIIPQLKkKHEI-STVDLVFLD 187
457899*******9************************************987777232467777555436777.89999**99 PP
>> tr|F7FVJ3|F7FVJ3_MONDO Protein-L-isoaspartate O-methyltransferase OS=Monodelphis domestica OX=13616 GN=PCMT1 PE=3 SV
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 16.6 0.0 1.9e-06 0.0056 37 89 .. 141 193 .. 130 246 .. 0.83
Alignments for each domain:
== domain 1 score: 16.6 bits; conditional E-value: 1.9e-06
GCD14 37 elkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehe 89
+l+ G+++++ G Gsg l+ +ar v+ tG++ +++ ++ ++ ++ + ++++
tr|F7FVJ3|F7FVJ3_MONDO 141 QLHDGAKALDVGSGSGILTACFARMVGATGKVIGIDHIKELVDDSISNVKKDD 193
5789*********************************9999999999888765 PP
>> tr|F6VKL8|F6VKL8_MONDO Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 OS=Monodelphis d
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 13.9 0.0 1.3e-05 0.038 30 84 .. 70 124 .. 57 132 .. 0.92
Alignments for each domain:
== domain 1 score: 13.9 bits; conditional E-value: 1.3e-05
GCD14 30 sliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekaree 84
s ++ L+l+pG ++ G G+g ls+ + ++P G + +e h + +e a+++
tr|F6VKL8|F6VKL8_MONDO 70 SEVMEALDLQPGLSFLNLGSGTGYLSSMVGLILGPFGVNHGVELHSDVIEYAKQK 124
568899*****************************************99999875 PP
>> tr|F6QTB4|F6QTB4_MONDO Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 OS=Monodelphis d
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.5 0.0 3.4e-05 0.1 30 86 .. 70 126 .. 60 141 .. 0.90
2 ? -3.7 0.0 3 9.2e+03 208 222 .. 306 320 .. 294 347 .. 0.57
Alignments for each domain:
== domain 1 score: 12.5 bits; conditional E-value: 3.4e-05
GCD14 30 sliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefr 86
s ++ L+l+pG ++ G G+g ls+ + +P G + +e h + +e a+e+++
tr|F6QTB4|F6QTB4_MONDO 70 SEVMEALKLQPGLSFLNLGSGTGYLSTMTSLVRSPFGINHGIELHSDVVEYAKEKLE 126
568899***********99999999999998889**************999998765 PP
== domain 2 score: -3.7 bits; conditional E-value: 3
GCD14 208 rkaskdakvedkssk 222
+k+++d+k e+++++
tr|F6QTB4|F6QTB4_MONDO 306 EKMEEDHKEEEEKDQ 320
333333333333333 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (247 nodes)
Target sequences: 21272 (11266248 residues searched)
Passed MSV filter: 1397 (0.0656732); expected 425.4 (0.02)
Passed bias filter: 935 (0.0439545); expected 425.4 (0.02)
Passed Vit filter: 119 (0.00559421); expected 21.3 (0.001)
Passed Fwd filter: 53 (0.00249154); expected 0.2 (1e-05)
Initial search space (Z): 21272 [actual number of targets]
Domain search space (domZ): 7 [number of targets reported over threshold]
# CPU time: 0.51u 0.02s 00:00:00.53 Elapsed: 00:00:00.21
# Mc/sec: 13251.25
//
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