# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/GCD14.hmm.txt
# target sequence database: proteomes/Nematostella_vectensis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: GCD14 [M=247]
Accession: PF08704.9
Description: tRNA methyltransferase complex GCD14 subunit
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
5.3e-90 301.8 0.0 7.3e-90 301.4 0.0 1.1 1 tr|A7RHG9|A7RHG9_NEMVE tRNA (adenine(58)-N(1))-methyltransfe
7.4e-07 29.5 0.1 9.9e-07 29.1 0.1 1.1 1 tr|A7S758|A7S758_NEMVE Predicted protein OS=Nematostella vec
8.4e-05 22.8 0.0 0.00012 22.3 0.0 1.1 1 tr|A7S8G2|A7S8G2_NEMVE Predicted protein OS=Nematostella vec
0.00021 21.5 0.0 0.00027 21.1 0.0 1.2 1 tr|A7RWP0|A7RWP0_NEMVE Predicted protein OS=Nematostella vec
0.0031 17.7 11.4 0.35 11.0 2.0 2.8 2 tr|A7SRL0|A7SRL0_NEMVE Predicted protein OS=Nematostella vec
0.0049 17.0 0.0 0.0079 16.3 0.0 1.4 1 tr|A7SXL3|A7SXL3_NEMVE Protein-L-isoaspartate O-methyltransf
0.0062 16.7 0.0 0.0086 16.2 0.0 1.3 1 tr|A7SY89|A7SY89_NEMVE Predicted protein (Fragment) OS=Nemat
0.008 16.3 0.0 0.031 14.4 0.0 1.9 2 tr|A7RT21|A7RT21_NEMVE Predicted protein OS=Nematostella vec
------ inclusion threshold ------
0.39 10.8 2.0 0.55 10.3 2.0 1.2 1 tr|A7SSV4|A7SSV4_NEMVE Predicted protein OS=Nematostella vec
Domain annotation for each sequence (and alignments):
>> tr|A7RHG9|A7RHG9_NEMVE tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A OS=Nematostella vectensis
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 301.4 0.0 2.7e-93 7.3e-90 1 192 [. 61 250 .. 61 255 .. 0.97
Alignments for each domain:
== domain 1 score: 301.4 bits; conditional E-value: 2.7e-93
GCD14 1 gfvyvlaptPeLWtlaLphrtqilytaDisliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefre 87
g++++l+ptPeLWt++Lphrtqily++Dis++ m+L++kpGsvv+esGtGs+s+sha++r++aPtGhl+t+efhe+r ++ar+ef +
tr|A7RHG9|A7RHG9_NEMVE 61 GYLFLLHPTPELWTINLPHRTQILYSTDISMVLMQLDIKPGSVVMESGTGSASMSHALIRSIAPTGHLYTYEFHEERSKQARKEFID 147
799************************************************************************************ PP
GCD14 88 helsqlvtvthrDvckeGf.deevsgkvDavfLDlPaPweaiphaakalkkeggrlCsfsPCieqvqrtceaLrelgfteietlevl 173
h++++lvtvthr+v +Gf +e++ +DavfLDlP+Pw+ai+ +kalk+eggrlCsfsPCieqvq+tc ++r+ gf +i+++e l
tr|A7RHG9|A7RHG9_NEMVE 148 HNVDHLVTVTHRNVTADGFlEENI---ADAVFLDLPSPWDAIKFSKKALKREGGRLCSFSPCIEQVQKTCGVMRDNGFRDIQVMECL 231
*******************55555...************************************************************ PP
GCD14 174 lrtyevrkskleeidlaek 192
l+t++v+++++++ d +ek
tr|A7RHG9|A7RHG9_NEMVE 232 LKTFDVKTVSYQMPDFGEK 250
*************998765 PP
>> tr|A7S758|A7S758_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g167288 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 29.1 0.1 3.6e-10 9.9e-07 31 121 .. 9 100 .. 4 122 .. 0.90
Alignments for each domain:
== domain 1 score: 29.1 bits; conditional E-value: 3.6e-10
GCD14 31 liimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtvthrDvckeGf.deevsgkvDa 116
++ m+ ++ + +v++ Gt +g + a+a + P G++ t+ef ++ a++a + fr+ ++ + +++ D+ + ++k D
tr|A7S758|A7S758_NEMVE 9 FLKMMAQIANAKRVLDVGTFTGMSAMAFAEGIPPDGQVVTIEFDQTIASTADKLFRDSAQAHKLALKVGDAVDVMTdLKSAQEKFDI 95
6789999***************999*******************************************999866553577889**** PP
GCD14 117 vfLDl 121
+fLD
tr|A7S758|A7S758_NEMVE 96 IFLDA 100
***96 PP
>> tr|A7S8G2|A7S8G2_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g186929 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 22.3 0.0 4.4e-08 0.00012 35 151 .. 132 249 .. 124 261 .. 0.69
Alignments for each domain:
== domain 1 score: 22.3 bits; conditional E-value: 4.4e-08
GCD14 35 kLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtvthrDvc.keGfdeevsgkvDavfLD 120
k+++ pGs+v+ G+ sg+ + ++ v+P G ++++ef ++ + + + +++ +++v + D+ + + + + g vD++f D
tr|A7S8G2|A7S8G2_NEMVE 132 KIHMPPGSKVLYLGAASGTTVSHVSDIVGPEGLVYAVEFSHRSGRDLI-NVAKKR-TNIVPI-IEDARhPHKY-RMLVGMVDCIFAD 214
67889***************9******************654443333.333332.233333.3455514555.5677********* PP
GCD14 121 lPaPwea...iphaakalkkeggrlCsf.sPCieq 151
+ +P++ +a + lk+ g + s + Ci+
tr|A7S8G2|A7S8G2_NEMVE 215 VAQPDQTrivAINAHNFLKNGGHFVISIkANCIDS 249
****9863212355666766555555542567765 PP
>> tr|A7RWP0|A7RWP0_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g203274 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 21.1 0.0 1e-07 0.00027 34 94 .. 72 132 .. 62 184 .. 0.78
Alignments for each domain:
== domain 1 score: 21.1 bits; conditional E-value: 1e-07
GCD14 34 mkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlv 94
+ +lk+G+ +++ G Gsg l+ +a v+ +G+++ +++ +q +++a+++ ++ + + l
tr|A7RWP0|A7RWP0_NEMVE 72 LEDQLKEGATALDVGSGSGYLTACMAYMVGEKGKVYGIDHIDQLVTEAKNNIKKGNPELLS 132
455799********************************************99987654444 PP
>> tr|A7SRL0|A7SRL0_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g216349 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 11.0 2.0 0.00013 0.35 151 220 .. 3 71 .. 1 82 [. 0.65
2 ! 10.4 2.7 0.00018 0.5 163 215 .. 85 137 .. 75 148 .] 0.52
Alignments for each domain:
== domain 1 score: 11.0 bits; conditional E-value: 0.00013
GCD14 151 qvqrtceaLrelgfteietlevllrtyevrkskleeidlaekrleenerkriekakrrkaskdakvedks 220
qv +++r+ g e+++ ++++r+ ++r++ ++++ +++ ++ +++ + ++++ ++++ + +d+
tr|A7SRL0|A7SRL0_NEMVE 3 QVDIRQNNMRQVGMREVDMSQIDIRQVDTREVGMRQVGMSQVHMRQVDMR-QVGMRQVDMKEADMRQDNM 71
55555667788888888888888888888888888888877777777544.4455555554444444433 PP
== domain 2 score: 10.4 bits; conditional E-value: 0.00018
GCD14 163 gfteietlevllrtyevrkskleeidlaekrleenerkriekakrrkaskdak 215
+ ++++ ev +r+ ++r+++++e+d+ ++++ e++ ++++ +k + d k
tr|A7SRL0|A7SRL0_NEMVE 85 DIRQVDMGEVGIRQVDMRQVDMKEVDMRQDNMREVDIRQVDMRKVDMRQVDMK 137
44555666666666666666666666666666666555444433322222222 PP
>> tr|A7SXL3|A7SXL3_NEMVE Protein-L-isoaspartate O-methyltransferase OS=Nematostella vectensis OX=45351 GN=v1g136839 PE
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 16.3 0.0 2.9e-06 0.0079 36 85 .. 74 123 .. 64 166 .. 0.87
Alignments for each domain:
== domain 1 score: 16.3 bits; conditional E-value: 2.9e-06
GCD14 36 LelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareef 85
++++G++v++ G Gsg l+ +a v+ tG++ +++ ++ ++ +r++
tr|A7SXL3|A7SXL3_NEMVE 74 DNIREGAKVLDVGSGSGYLTAVMAIMVGKTGKVVGIDHIQELVDMSRKNV 123
5799************************************9999999876 PP
>> tr|A7SY89|A7SY89_NEMVE Predicted protein (Fragment) OS=Nematostella vectensis OX=45351 GN=v1g137654 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 16.2 0.0 3.2e-06 0.0086 30 95 .. 70 134 .. 45 160 .. 0.83
Alignments for each domain:
== domain 1 score: 16.2 bits; conditional E-value: 3.2e-06
GCD14 30 sliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvt 95
s ++ Lel++G ++ G G+g ls+ + ++P G + +e e+ +++a +++ h ++++
tr|A7SY89|A7SY89_NEMVE 70 SEVMECLELEEGLSFLNLGSGTGYLSTMVGLIIGPSGTNHGVELFEDVVDFAHSKLQ-HFMENNPA 134
567889********************************************9998765.45555555 PP
>> tr|A7RT21|A7RT21_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g240471 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -0.8 0.0 0.49 1.3e+03 184 242 .. 142 200 .. 134 205 .. 0.84
2 ! 14.4 0.0 1.2e-05 0.031 13 95 .. 194 277 .. 183 286 .. 0.79
Alignments for each domain:
== domain 1 score: -0.8 bits; conditional E-value: 0.49
GCD14 184 leeidlaekrleenerkriekakrrkaskdakvedkssksstevllkPvselkghtgyL 242
l+++d +k+ +e++ + + +++r + +k+ ++ + ++++ P ++l+ ht y+
tr|A7RT21|A7RT21_NEMVE 142 LTTADKVIKHFQEESYHLVPSTDKRLYVEGSKIFAQDPHIPEVLVFPPSTDLHDHTLYI 200
6677888888888888888889999999999999999999999999999*******997 PP
== domain 2 score: 14.4 bits; conditional E-value: 1.2e-05
GCD14 13 WtlaLphrtqilytaDisli.imkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvt 95
+L il + s + + + l pG+ v+++ + g s+ +a ++ G++f+f+ ++r ++++++ + + +vt
tr|A7RT21|A7RT21_NEMVE 194 HDHTLYINGHILLQDKASCLpAHVISLPPGAHVIDACAAPGNKSSHLAAKLNNNGRVFSFDISASRLAVMQKQMKKAGATCVVT 277
5555555566666655555425678999*****************************************999999988766665 PP
>> tr|A7SSV4|A7SSV4_NEMVE Predicted protein OS=Nematostella vectensis OX=45351 GN=v1g247204 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 10.3 2.0 0.0002 0.55 151 209 .. 57 119 .. 49 141 .. 0.78
Alignments for each domain:
== domain 1 score: 10.3 bits; conditional E-value: 0.0002
GCD14 151 qvqrtceaLrelgfteietle...vllrtyevrkskleeidlaekrleenerkri.ekakrrk 209
qr +e+ +e+ f++ietle lr+y + ++lee+ + krl++ + ++ k+k+ k
tr|A7SSV4|A7SSV4_NEMVE 57 ESQREVEEEQEKLFKDIETLEdenFYLRKYVDKIQELEEMTNTSKRLDQLKDRQQrRKIKELK 119
679999**************95545689*********99999999998876553302333333 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (247 nodes)
Target sequences: 24428 (8257945 residues searched)
Passed MSV filter: 1174 (0.0480596); expected 488.6 (0.02)
Passed bias filter: 747 (0.0305797); expected 488.6 (0.02)
Passed Vit filter: 74 (0.00302931); expected 24.4 (0.001)
Passed Fwd filter: 17 (0.000695923); expected 0.2 (1e-05)
Initial search space (Z): 24428 [actual number of targets]
Domain search space (domZ): 9 [number of targets reported over threshold]
# CPU time: 0.28u 0.01s 00:00:00.29 Elapsed: 00:00:00.09
# Mc/sec: 22663.47
//
[ok]