# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/GCD14.hmm.txt
# target sequence database:        proteomes/Ornithorhynchus_anatinus.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       GCD14  [M=247]
Accession:   PF08704.9
Description: tRNA methyltransferase complex GCD14 subunit
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    5.8e-75  252.4   0.0    7.2e-75  252.1   0.0    1.1  1  tr|F6RDG7|F6RDG7_ORNAN  Uncharacterized protein OS=Ornithorhy
    2.3e-18   67.0   0.0    3.4e-18   66.5   0.0    1.2  1  tr|F7BD68|F7BD68_ORNAN  Uncharacterized protein OS=Ornithorhy
    5.1e-05   23.3   0.0    7.1e-05   22.9   0.0    1.2  1  tr|F7DSB1|F7DSB1_ORNAN  Uncharacterized protein OS=Ornithorhy
    0.00027   21.0   0.0    0.00036   20.6   0.0    1.2  1  tr|F6YGL3|F6YGL3_ORNAN  Protein-L-isoaspartate O-methyltransf
     0.0094   15.9   0.0      0.019   14.9   0.0    1.4  1  tr|F7CKF0|F7CKF0_ORNAN  Protein-L-isoaspartate (D-aspartate) 
  ------ inclusion threshold ------
       0.02   14.9   0.0      0.038   13.9   0.0    1.4  1  tr|F7FMN0|F7FMN0_ORNAN  Uncharacterized protein OS=Ornithorhy


Domain annotation for each sequence (and alignments):
>> tr|F6RDG7|F6RDG7_ORNAN  Uncharacterized protein OS=Ornithorhynchus anatinus OX=9258 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  252.1   0.0     2e-78   7.2e-75      48     247 .]       1     190 [.       1     190 [. 0.97

  Alignments for each domain:
  == domain 1  score: 252.1 bits;  conditional E-value: 2e-78
                   GCD14  48 GtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtvthrDvckeGfdeevsgkvDavfLDlPaPweaiphaaka 134
                             GtGsgslsha++rt+aPtGhl+t+efh+qraeka+eefr h++++lvtv+++Dvck+Gf  +v++ +DavfLD+P+Pwea++ha +a
  tr|F6RDG7|F6RDG7_ORNAN   1 GTGSGSLSHALLRTIAPTGHLYTVEFHQQRAEKAMEEFRAHKVDHLVTVRNQDVCKNGF--GVTHAADAVFLDIPSPWEAVGHANAA 85 
                             9**********************************************************..9************************* PP

                   GCD14 135 lkkeggrlCsfsPCieqvqrtceaLrelgfteietlevllrtyevrkskleeidlaekrleenerkriekakrrkaskdakvedkss 221
                             l+ eggrlCsfsPCieqvqrtc+aL+e+gfte++tle+ll+ y+vr+++l+  dl++ ++ +      + a  +       +++ks+
  tr|F6RDG7|F6RDG7_ORNAN  86 LRVEGGRLCSFSPCIEQVQRTCRALEEHGFTEVHTLEILLQAYNVRTVNLPLPDLGKGATADAADAPSDVAADSGPPPPGMAQFKSG 172
                             *********************************************************999999888778888888899999999999 PP

                   GCD14 222 ksstevllkPvselkghtgyLtfatk 247
                                      P++e++ghtgyLtfatk
  tr|F6RDG7|F6RDG7_ORNAN 173 V--------PLKEMVGHTGYLTFATK 190
                             9........***************86 PP

>> tr|F7BD68|F7BD68_ORNAN  Uncharacterized protein OS=Ornithorhynchus anatinus OX=9258 GN=TRMT61B PE=4 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   66.5   0.0   9.3e-22   3.4e-18      17     243 ..     169     416 ..     153     420 .. 0.70

  Alignments for each domain:
  == domain 1  score: 66.5 bits;  conditional E-value: 9.3e-22
                   GCD14  17 LphrtqilytaDisliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehel..........sql 93 
                             ++    i y +D+ +++m++++++G  v+e G Gsg +s  ++++v+ +G++ +fe  ++  e a++++++              ++
  tr|F7BD68|F7BD68_ORNAN 169 MKRGPNISYPKDVNMMVMMMDVHQGDAVLEVGSGSGGMSLFLSKAVGSQGRVMSFEIRKDHHEIAKKNYKNWCNawkishseewPEN 255
                             44556799************************************************************9974222333666554679 PP

                   GCD14  94 vtvthrDvckeGfdeevsgkvDavfLDlPaPweaiphaakalkkeggrlCsfsPCieqvqrtceaLre...lgfteietlevllrty 177
                             v   h+D+ +   d + s++ Dav LD+ +P  a+p + + l k+gg+   +   i q+ +  + +++     ++e +  ev lr +
  tr|F7BD68|F7BD68_ORNAN 256 VDFIHKDIATAAQDLK-SKTFDAVALDMLNPQIALPIVYQSL-KQGGVCTIYLASITQIIELLNGISScrlALYCE-KITEVTLRDW 339
                             ********99877444.3679*********************.778877778899999877665555411155676.6779999999 PP

                   GCD14 178 evrkskleeidl...aekrleenerkriekakrrka.skdakvedkssks.......stevllkPvselkghtgyLt 243
                              v   k +        + +++ +++ ++++ ++ +  ++++ + + ++++           +++P++   ght++L+
  tr|F7BD68|F7BD68_ORNAN 340 LVCPAKKKDGTFvqrVQPTTNLDSELHTHEDDEGEEgEEEQVQAEDNGETlsdspygAVPYIARPLHWQCGHTAFLI 416
                             875444443333100222222222222222222222122222222222224555665777899************96 PP

>> tr|F7DSB1|F7DSB1_ORNAN  Uncharacterized protein OS=Ornithorhynchus anatinus OX=9258 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   22.9   0.0     2e-08   7.1e-05      34     141 ..     100     207 ..      91     239 .. 0.71

  Alignments for each domain:
  == domain 1  score: 22.9 bits;  conditional E-value: 2e-08
                   GCD14  34 mkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtvthrDvc.keGfdeevsgkvDavfL 119
                              ++++kpG++v+  G+ sg+  + ++  v+P G ++++ef ++  +  + +  +++ ++++ v   D+   + + + + g vD +f 
  tr|F7DSB1|F7DSB1_ORNAN 100 DQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRD-LINVAKKR-TNVIPVI-EDARhPHKY-RMLIGMVDVIFA 182
                             5789************************************7644444.43443333.2344444.455425666.5566******** PP

                   GCD14 120 DlPaPwea..i.phaakalkkeggr 141
                             D+ +P+++  +  +a + l++ g  
  tr|F7DSB1|F7DSB1_ORNAN 183 DVAQPDQSriVaLNAHNFLRNGGHF 207
                             *****98632212445555444444 PP

>> tr|F6YGL3|F6YGL3_ORNAN  Protein-L-isoaspartate O-methyltransferase OS=Ornithorhynchus anatinus OX=9258 GN=PCMT1 PE=3 
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   20.6   0.0   9.9e-08   0.00036      37      94 ..     126     183 ..     115     231 .. 0.81

  Alignments for each domain:
  == domain 1  score: 20.6 bits;  conditional E-value: 9.9e-08
                   GCD14  37 elkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlv 94 
                             +l++G+++++ G Gsg l+  ++r v+P G++  +++ ++ ++ ++++ ++++ s l+
  tr|F6YGL3|F6YGL3_ORNAN 126 QLHEGAKALDVGSGSGILTACFSRMVGPIGKVVGIDHIKELVDDSINNVKKDDPSFLT 183
                             5789***************************************999999988765544 PP

>> tr|F7CKF0|F7CKF0_ORNAN  Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 OS=Ornithorhynch
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.9   0.0   5.2e-06     0.019      30      86 ..      70     126 ..      60     140 .. 0.92

  Alignments for each domain:
  == domain 1  score: 14.9 bits;  conditional E-value: 5.2e-06
                   GCD14  30 sliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefr 86 
                             s ++  L+l+pG   ++ G G+g ls+ +   ++P G  + +e h + +e a+e+++
  tr|F7CKF0|F7CKF0_ORNAN  70 SEVMEALKLQPGLSFLNLGSGTGYLSTMVGLILGPFGINHGIELHSDVVEYAKEKLE 126
                             568899******************************************999998765 PP

>> tr|F7FMN0|F7FMN0_ORNAN  Uncharacterized protein OS=Ornithorhynchus anatinus OX=9258 GN=PCMTD2 PE=4 SV=2
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.9   0.0     1e-05     0.038      30      84 ..      70     124 ..      57     132 .. 0.92

  Alignments for each domain:
  == domain 1  score: 13.9 bits;  conditional E-value: 1e-05
                   GCD14  30 sliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekaree 84 
                             s ++  L+l+pG   ++ G G+g ls+ +   ++P G  + +e h + +e a+++
  tr|F7FMN0|F7FMN0_ORNAN  70 SEVMEALDLQPGLSFLNLGSGTGYLSSMVGLILGPFGVNHGVELHSDVIEYAKQK 124
                             568899*****************************************99999875 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (247 nodes)
Target sequences:                        21677  (8259262 residues searched)
Passed MSV filter:                       967  (0.0446095); expected 433.5 (0.02)
Passed bias filter:                      670  (0.0309083); expected 433.5 (0.02)
Passed Vit filter:                        67  (0.00309083); expected 21.7 (0.001)
Passed Fwd filter:                        10  (0.000461318); expected 0.2 (1e-05)
Initial search space (Z):              21677  [actual number of targets]
Domain search space  (domZ):               6  [number of targets reported over threshold]
# CPU time: 0.25u 0.01s 00:00:00.26 Elapsed: 00:00:00.09
# Mc/sec: 22667.09
//
[ok]