# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/GCD14.hmm.txt
# target sequence database: proteomes/Petromyzon_marinus.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: GCD14 [M=247]
Accession: PF08704.9
Description: tRNA methyltransferase complex GCD14 subunit
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
9.6e-96 319.8 0.0 1.3e-95 319.4 0.0 1.2 1 tr|S4RY21|S4RY21_PETMA tRNA (adenine(58)-N(1))-methyltransfe
3.5e-07 29.8 0.0 4.6e-07 29.4 0.0 1.2 1 tr|S4R827|S4R827_PETMA Protein-L-isoaspartate (D-aspartate)
4.6e-05 22.8 0.0 9.5e-05 21.8 0.0 1.5 2 tr|S4RW29|S4RW29_PETMA Protein-L-isoaspartate O-methyltransf
0.0001 21.6 0.1 0.00021 20.6 0.1 1.4 1 tr|S4RTL8|S4RTL8_PETMA Fibrillarin OS=Petromyzon marinus OX=
0.002 17.4 0.0 0.018 14.4 0.0 2.1 2 tr|S4RHT4|S4RHT4_PETMA tRNA (guanine(26)-N(2))-dimethyltrans
------ inclusion threshold ------
0.022 14.0 0.1 0.03 13.6 0.1 1.2 1 tr|S4RCL0|S4RCL0_PETMA Uncharacterized protein OS=Petromyzon
Domain annotation for each sequence (and alignments):
>> tr|S4RY21|S4RY21_PETMA tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A OS=Petromyzon marinus OX=
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 319.4 0.0 5.7e-99 1.3e-95 1 246 [. 65 305 .. 65 306 .. 0.92
Alignments for each domain:
== domain 1 score: 319.4 bits; conditional E-value: 5.7e-99
GCD14 1 gfvyvlaptPeLWtlaLphrtqilytaDisliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefre 87
g++y l+ptPeLWt +Lphrtqily++Di++++ +L+l+pGsvv+esGtGsgslsha++rt+aP Ghl+t+efheqra +a eef++
tr|S4RY21|S4RY21_PETMA 65 GWAYALHPTPELWTRSLPHRTQILYSTDIAMVTLMLDLRPGSVVCESGTGSGSLSHALLRTIAPSGHLHTVEFHEQRAASAAEEFER 151
8************************************************************************************** PP
GCD14 88 helsqlvtvthrDvckeGfdeevsgkvDavfLDlPaPweaiphaakalkkeggrlCsfsPCieqvqrtceaLrelgfteietlevll 174
h++ l tv+ rDvc++Gf +v g++DavfLD+P+Pw+a+pha +a+k++ggrlCsfsPCieqvqrtc+aL+ lgf+e +t+evll
tr|S4RY21|S4RY21_PETMA 152 HGVGRLATVRCRDVCRDGF--GVAGVADAVFLDIPSPWDAVPHARDAMKTSGGRLCSFSPCIEQVQRTCQALAGLGFVEPSTVEVLL 236
*******************..9***************************************************************** PP
GCD14 175 rtyevrkskleeidlaekrleenerkriekakrrkaskdakvedkssksstevllkPvselkghtgyLtfat 246
r +vr+++l++ dl++ + + + + +a v+ ++ + + P +e+ ghtgyLtfat
tr|S4RY21|S4RY21_PETMA 237 RPLDVRTVSLPVPDLGQGGVRASGDG--GRPRPPHAVPAGVVDSSRGV-YSFKAGCPPREMPGHTGYLTFAT 305
***************99988877544..23333445555666666666.555566788*************8 PP
>> tr|S4R827|S4R827_PETMA Protein-L-isoaspartate (D-aspartate) O-methyltransferase OS=Petromyzon marinus OX=7757 PE=4 S
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 29.4 0.0 2e-10 4.6e-07 35 106 .. 75 146 .. 57 187 .. 0.77
Alignments for each domain:
== domain 1 score: 29.4 bits; conditional E-value: 2e-10
GCD14 35 kLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtvthrDvckeGf 106
+ +l +G+ v++ G Gsg l+ iar v+ G++f +++ ++ +++a+++ +++++s l ++ v +G
tr|S4R827|S4R827_PETMA 75 QDHLFEGASVLDVGSGSGYLTACIARMVGSSGKVFGIDHIQELVDEAIKNVNKDDMSLLSSGQVTLVVGDGR 146
456789*************************************************95544444444444443 PP
>> tr|S4RW29|S4RW29_PETMA Protein-L-isoaspartate O-methyltransferase OS=Petromyzon marinus OX=7757 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 21.8 0.0 4.2e-08 9.5e-05 35 87 .. 96 148 .. 86 169 .. 0.89
2 ? -2.9 0.0 1.4 3.2e+03 45 68 .. 179 202 .. 170 203 .. 0.84
Alignments for each domain:
== domain 1 score: 21.8 bits; conditional E-value: 4.2e-08
GCD14 35 kLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefre 87
+ +l++G+ +++ G Gsg l+ +ar ++P+G++ +++ ++ +++a+ + ++
tr|S4RW29|S4RW29_PETMA 96 QDRLQEGASALDVGSGSGYLTACLARMIGPRGKVIGVDHIQELVSEAKVNVQR 148
55899************************************999999887766 PP
== domain 2 score: -2.9 bits; conditional E-value: 1.4
GCD14 45 vesGtGsgslshaiartvaPtGhl 68
+ G+ ++ + ha++ ++P G+l
tr|S4RW29|S4RW29_PETMA 179 IHVGAAAAIVPHALLDQLKPGGRL 202
667888899999999999999997 PP
>> tr|S4RTL8|S4RTL8_PETMA Fibrillarin OS=Petromyzon marinus OX=7757 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 20.6 0.1 9.5e-08 0.00021 35 150 .. 164 277 .. 156 293 .. 0.69
Alignments for each domain:
== domain 1 score: 20.6 bits; conditional E-value: 9.5e-08
GCD14 35 kLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareef..rehelsqlvtvthrDvckeGfdeevsgkvDavfL 119
++++kpG +v+ G+ sg+ + ++ v+P G ++++ef ++ + + + +++++ + +++ + + g vD vf
tr|S4RTL8|S4RTL8_PETMA 164 QIHIKPGVKVLYLGAASGTTVSHVSDIVGPEGLVYAVEFSHR-SGRDLMNVakKRTNIIPIYKLECSPI-------SLAGMVDVVFA 242
789************************************653.33334343003444444444444444.......456669***** PP
GCD14 120 DlPaPwea...iphaakalkkeggrlCsf.sPCie 150
D+ +P++ +a + lk+ g + s + Ci+
tr|S4RTL8|S4RTL8_PETMA 243 DVAQPDQTrivAINAHNFLKNGGHFVISIkANCID 277
*****986321234556665555555554245665 PP
>> tr|S4RHT4|S4RHT4_PETMA tRNA (guanine(26)-N(2))-dimethyltransferase OS=Petromyzon marinus OX=7757 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 14.4 0.0 7.8e-06 0.018 37 144 .. 138 246 .. 133 251 .. 0.93
2 ? 0.3 0.0 0.16 3.5e+02 44 80 .. 261 297 .. 249 313 .. 0.89
Alignments for each domain:
== domain 1 score: 14.4 bits; conditional E-value: 7.8e-06
GCD14 37 elkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtvthrDvckeGf.deevsgkvDavfLD.l 121
+ ++G +v+e+ + sg s +a+ + + t +f ++ + ++ + +++++lvt + D+ + +++ +++ D v LD
tr|S4RHT4|S4RHT4_PETMA 138 KCEEGVKVLEALAASGLRSIRFAKEIPGIKSIITNDFSKNAVAAINKNIEMNQVQHLVTASYSDASMLMYkSKNHKESFDVVDLDpY 224
5678******************************************************************77888999*******56 PP
GCD14 122 PaPweaiphaakalkkeggrlCs 144
+P + ++ a++ + +egg lC
tr|S4RHT4|S4RHT4_PETMA 225 GSPVQFLDAAVQSV-NEGGLLCV 246
79************.99****96 PP
== domain 2 score: 0.3 bits; conditional E-value: 0.16
GCD14 44 vvesGtGsgslshaiartvaPtGhlftfefheqraek 80
+ s Gs sl ++ +a + l+ ++ h +r+++
tr|S4RHT4|S4RHT4_PETMA 261 TCYSKYGSMSLKAKFCHEMALRIILHCLDLHSNRYHR 297
567888****************************975 PP
>> tr|S4RCL0|S4RCL0_PETMA Uncharacterized protein OS=Petromyzon marinus OX=7757 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 13.6 0.1 1.3e-05 0.03 10 140 .. 34 175 .. 27 181 .. 0.75
Alignments for each domain:
== domain 1 score: 13.6 bits; conditional E-value: 1.3e-05
GCD14 10 PeLW..tlaLphrtqilytaDisliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehel.... 90
P L+ tl ++ + i y + i +i+ + +k G v G s+ + + tv Gh+ + + e+ + a+ + + +
tr|S4RCL0|S4RCL0_PETMA 34 PSLYefTLFMSRTATIAYPKKIGVIMRTKIVKVGDPVQCGGVASARFGIVASATVWEPGHVVSCDVREDHLHVAQRNVASWRSaweq 120
55651155556666899************************************************9988888777665433322223 PP
GCD14 91 .......sqlvtvthrDvckeGfdeevsgkvDavfLDlPaPweaiphaakalkkegg 140
++ + Dv ++ ++ + + Dav LD+ + a+ + alk gg
tr|S4RCL0|S4RCL0_PETMA 121 argvdswPRNISFLKADVLRDTHLTH-QYTYDAVVLDMLNVHLAVSCVLPALK-PGG 175
33333333478888899998887333.3589*******999999999988884.444 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (247 nodes)
Target sequences: 13539 (5048892 residues searched)
Passed MSV filter: 503 (0.0371519); expected 270.8 (0.02)
Passed bias filter: 377 (0.0278455); expected 270.8 (0.02)
Passed Vit filter: 30 (0.00221582); expected 13.5 (0.001)
Passed Fwd filter: 7 (0.000517025); expected 0.1 (1e-05)
Initial search space (Z): 13539 [actual number of targets]
Domain search space (domZ): 6 [number of targets reported over threshold]
# CPU time: 0.15u 0.01s 00:00:00.16 Elapsed: 00:00:00.04
# Mc/sec: 31176.91
//
[ok]