# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/GCD14.hmm.txt
# target sequence database: proteomes/Saccharomyces_cerevisiae.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: GCD14 [M=247]
Accession: PF08704.9
Description: tRNA methyltransferase complex GCD14 subunit
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
4e-81 270.8 0.1 2.7e-80 268.1 0.1 2.0 1 sp|P46959|TRM61_YEAST tRNA (adenine(58)-N(1))-methyltransfer
5e-06 24.8 0.1 9.4e-06 23.9 0.1 1.3 1 sp|P15646|FBRL_YEAST rRNA 2'-O-methyltransferase fibrillari
------ inclusion threshold ------
0.015 13.5 0.0 0.024 12.8 0.0 1.3 1 sp|P40516|EFM4_YEAST Protein-lysine N-methyltransferase EFM
0.042 12.0 3.5 0.067 11.3 3.5 1.3 1 sp|Q06001|FAR10_YEAST Factor arrest protein 10 OS=Saccharomy
0.19 9.8 4.3 0.37 8.9 4.3 1.4 1 sp|P38882|UTP9_YEAST U3 small nucleolar RNA-associated prot
Domain annotation for each sequence (and alignments):
>> sp|P46959|TRM61_YEAST tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61 OS=Saccharomyces cerevisiae
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 268.1 0.1 2.2e-83 2.7e-80 2 246 .. 72 362 .. 71 363 .. 0.86
Alignments for each domain:
== domain 1 score: 268.1 bits; conditional E-value: 2.2e-83
GCD14 2 fvyvlaptPeLWtlaLphrtqilytaDisliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehe 89
fv+vl+ptPeLWtl+Lphrtqi+yt+D s i+++L+ p s+v+e+GtGsgs+sha+ar+v Ghlf+fefh+ r+e+a+eef+eh+
sp|P46959|TRM61_YEAST 72 FVHVLQPTPELWTLSLPHRTQIVYTPDSSYIMQRLNCSPHSRVIEAGTGSGSFSHAFARSV---GHLFSFEFHHIRYEQALEEFKEHG 156
9**********************************************************98...9*********************** PP
GCD14 90 l.sqlvtvthrDvckeGf..de......evsg.........kvDavfLDlPaPweaiphaakal.kkeggrlCsfsPCieqvqrtcea 158
l +++vt+thrDvc+ Gf ++ e +++ vfLDlPaPw+aiph+ +++ +e+ lC+fsPCieqv +t ++
sp|P46959|TRM61_YEAST 157 LiDDNVTITHRDVCQGGFliKKgdttsyE--FgnnetaaslNANVVFLDLPAPWDAIPHLDSVIsVDEKVGLCCFSPCIEQVDKTLDV 242
9677*************975322112221..01122222225778*******************6677788***************** PP
GCD14 159 Lrelgfteietlevllrtyevrkskleeidlaekrleenerkriekakrrkaskdakvedkssks..........stevllkPv.... 232
L++ g+t++e++e++ r+ye r++ ++ ++ a +rl + +r++ ++++rrk + +++++ +++k+ +++ +P+
sp|P46959|TRM61_YEAST 243 LEKYGWTDVEMVEIQGRQYESRRQMVRSLNDALERLRDIKRHKLQGVERRKRMFNNTIDSNDEKVgkrnedgvplTEKAKFNPFgkgs 330
***************************************************9888888888888777777778874444555557777 PP
GCD14 233 ..................selkghtgyLtfat 246
e+k+ht+yLtfa
sp|P46959|TRM61_YEAST 331 rikegdsnykwkevtkmeAEIKSHTSYLTFAF 362
7777777777777777779***********96 PP
>> sp|P15646|FBRL_YEAST rRNA 2'-O-methyltransferase fibrillarin OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 23.9 0.1 7.8e-09 9.4e-06 35 152 .. 161 279 .. 155 307 .. 0.73
Alignments for each domain:
== domain 1 score: 23.9 bits; conditional E-value: 7.8e-09
GCD14 35 kLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtvthrDvc.keGfdeevsgkvDavfLDlP 122
+L + pG +v+ G+ sg+ + ++ v+P G ++++ef ++ ++ + +++ ++ D+ + + + + g vD+vf D+
sp|P15646|FBRL_YEAST 161 ELFIAPGKKVLYLGAASGTSVSHVSDVVGPEGVVYAVEFSHRPGRELISMAKKR---PNIIPIIEDARhPQKY-RMLIGMVDCVFADVA 245
57799************9887889***************776555544443333...2333333454414445.4566*********** PP
GCD14 123 aPwea.iphaakal..kkeggrlCsf.sPCieqv 152
+P++a i + +++ k++gg++ s + Ci+
sp|P15646|FBRL_YEAST 246 QPDQArIIALNSHMflKDQGGVVISIkANCIDST 279
****965555566667999999998735799764 PP
>> sp|P40516|EFM4_YEAST Protein-lysine N-methyltransferase EFM4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.8 0.0 2e-05 0.024 37 103 .. 90 155 .. 80 177 .. 0.88
Alignments for each domain:
== domain 1 score: 12.8 bits; conditional E-value: 2e-05
GCD14 37 elkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtvthrDvck 103
++ + + vv+ GtG g + + +t + +G+l +++ e+ ++ a + + +++++++ ++ D+ +
sp|P40516|EFM4_YEAST 90 RISENASVVDLGTGNGHMLFELHQT-EFQGKLVGIDYSEESVKLASNIAEATGVDNFISFQQADIFS 155
7888999**************9987.789**********************************9975 PP
>> sp|Q06001|FAR10_YEAST Factor arrest protein 10 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.3 3.5 5.5e-05 0.067 148 244 .. 350 460 .. 333 463 .. 0.60
Alignments for each domain:
== domain 1 score: 11.3 bits; conditional E-value: 5.5e-05
GCD14 148 CieqvqrtceaLrelgfteietlevllrtyevrkskleeidlaekrleenerkriekakrrkaskdakvedkssksstevllkPv... 232
ieq ++ +++L+ + +++ev r+++ +++++e + k+ e+er + +++ +++++k+++ ++ s k +te ++ v
sp|Q06001|FAR10_YEAST 350 IIEQNRNQVKQLERDHMFFKKSFEVKKRRNNEKQKSMEREIEDLKTRLEVERYKNSQMMKKNKQKEQELSTASKKKTTEHDTRGVpgm 437
69**********988877889**********999999865443333333333333333333333333333333332333333322334 PP
GCD14 233 ...........selkghtgyLtf 244
++l h + Ltf
sp|Q06001|FAR10_YEAST 438 npkgtdkfsikNTLCNHFTLLTF 460
44455555554556666666666 PP
>> sp|P38882|UTP9_YEAST U3 small nucleolar RNA-associated protein 9 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 8.9 4.3 0.00031 0.37 135 226 .. 290 385 .. 280 402 .. 0.75
Alignments for each domain:
== domain 1 score: 8.9 bits; conditional E-value: 0.00031
GCD14 135 lkkeggrlCsfsPCi..eqvqrtceaLrelgfteietlevllrtyev.rkskleeidl.aekrleenerkriekakrrkaskdakvedk 219
+ +e+ + f+P +qv + +++e +f i+ e+ ++ y + k++ +++d+ +k+lee+e+++ +++++k++ ++k+++k
sp|P38882|UTP9_YEAST 290 VVNEDLEIIDFTPINskQQVLISWLNVNEPNFESISLKEIETQGYITiNKNEKNNADEaDQKKLEEKEEEAQPEVQHEKKETETKINKK 378
556777788888865114555666778899*************9965266777788885677889999999999999999999999999 PP
GCD14 220 ssksste 226
sks+++
sp|P38882|UTP9_YEAST 379 VSKSDQV 385
9996444 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (247 nodes)
Target sequences: 6049 (2936363 residues searched)
Passed MSV filter: 581 (0.0960489); expected 121.0 (0.02)
Passed bias filter: 361 (0.0596793); expected 121.0 (0.02)
Passed Vit filter: 44 (0.00727393); expected 6.0 (0.001)
Passed Fwd filter: 10 (0.00165317); expected 0.1 (1e-05)
Initial search space (Z): 6049 [actual number of targets]
Domain search space (domZ): 5 [number of targets reported over threshold]
# CPU time: 0.14u 0.00s 00:00:00.14 Elapsed: 00:00:00.06
# Mc/sec: 12088.03
//
[ok]