# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/GCD14.hmm.txt
# target sequence database:        proteomes/Trichoplax_adhaerens.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       GCD14  [M=247]
Accession:   PF08704.9
Description: tRNA methyltransferase complex GCD14 subunit
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    2.6e-90  301.8   0.0    3.4e-90  301.4   0.0    1.2  1  tr|B3S082|B3S082_TRIAD  tRNA (adenine(58)-N(1))-methyltransfe
    3.3e-15   55.8   0.0    4.7e-15   55.3   0.0    1.1  1  tr|B3S6G3|B3S6G3_TRIAD  Uncharacterized protein OS=Trichoplax
    6.9e-06   25.3   0.0      1e-05   24.7   0.0    1.2  1  tr|B3S5V8|B3S5V8_TRIAD  Uncharacterized protein OS=Trichoplax
     0.0027   16.8   0.0     0.0042   16.2   0.0    1.4  1  tr|B3RJQ6|B3RJQ6_TRIAD  Protein-L-isoaspartate O-methyltransf
     0.0092   15.1   1.1      0.015   14.4   0.4    1.6  2  tr|B3RRK7|B3RRK7_TRIAD  Uncharacterized protein OS=Trichoplax


Domain annotation for each sequence (and alignments):
>> tr|B3S082|B3S082_TRIAD  tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A OS=Trichoplax adhaerens O
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  301.4   0.0   1.5e-93   3.4e-90       1     246 [.      64     296 ..      64     297 .. 0.91

  Alignments for each domain:
  == domain 1  score: 301.4 bits;  conditional E-value: 1.5e-93
                   GCD14   1 gfvyvlaptPeLWtlaLphrtqilytaDisliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefre 87 
                             g++y+l+pt eLWtl+L hrtq++y++Dis+ii +Le+ pG+ v+esGtGsgslshai+r+v+P G+l t+efh++ra+ka ++f+ 
  tr|B3S082|B3S082_TRIAD  64 GWLYILHPTAELWTLSLLHRTQVIYSTDISMIISELEIMPGCLVIESGTGSGSLSHAIIRAVSPNGKLLTYEFHNERADKAENDFKL 150
                             8************************************************************************************** PP

                   GCD14  88 helsqlvtvthrDvckeGfdeevsgkvDavfLDlPaPweaiphaakalkkeggrlCsfsPCieqvqrtceaLrelgfteietlevll 174
                             ++l++lvtv+ r+vc+eGf  ++++++Dav LDlP Pweaip a++al k ggr+C+fsPCieqvqr+c  Lr++gf+++++le  l
  tr|B3S082|B3S082_TRIAD 151 NGLNHLVTVHCRNVCQEGF--DITSEADAVILDLPIPWEAIPYAKQAL-KPGGRICCFSPCIEQVQRSCMCLRDHGFIDVKVLETIL 234
                             *******************..9**************************.99************************************ PP

                   GCD14 175 rtyevrkskleeidlaekrleenerkriekakrrkaskdakvedksskss.tevllkPvselkghtgyLtfat 246
                             r y v+k++l+ ++ ++ +  +++++        +   d +++++++ks+ + + + Pv ++ ghtgyLtfat
  tr|B3S082|B3S082_TRIAD 235 RPYRVKKMELPIANTGNCESFQSNER--------S---DPSTSHHENKSKrELLSTFPVATTPGHTGYLTFAT 296
                             ************99977655444333........2...2222222222220344567***************8 PP

>> tr|B3S6G3|B3S6G3_TRIAD  Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_59795 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   55.3   0.0   2.1e-18   4.7e-15       7     200 ..      77     279 ..      72     300 .. 0.83

  Alignments for each domain:
  == domain 1  score: 55.3 bits;  conditional E-value: 2.1e-18
                   GCD14   7 aptPeLWtlaLphrtqilytaDisliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehel... 90 
                             +pt e + l ++    + y +D + +++++++  Gs+v+esG Gsg l+  ++r+v+  G++ ++e      e ar++ +  +    
  tr|B3S6G3|B3S6G3_TRIAD  77 RPTLEDYILHMKRGPTVTYPKDAAAMVTMMDIGCGSKVLESGSGSGGLTLFLSRAVGNEGRIDSYEVRSGHLEIARKNVQAWKGswn 163
                             577777778888888899*************************************************99999999999886543333 PP

                   GCD14  91 .......sqlvtvthrDvckeGf.deevsgkvDavfLDlPaPweaiphaakalkkeggrlCsfsPCieqvqrtceaLrelg..ftei 167
                                     +++   h+Dv k     ++v    Dav LDl    + +p + k+l + g  + ++ P i qv  t ++++++   f   
  tr|B3S6G3|B3S6G3_TRIAD 164 vnhlqtwPDNIYFFHQDVIKALTmPTDV---FDAVALDLQDLSDVLPFVLKVL-RIGRPVVAYLPNITQVITTLQRIKQQSlpFSLD 246
                             44445555689999****9775547777...9*********************.7788899**************998754228888 PP

                   GCD14 168 etlevllrtyevrkskleeidlaekrleenerk 200
                             +++ev  + +++  sk  + + ++++ e+n +k
  tr|B3S6G3|B3S6G3_TRIAD 247 RVVEVYHKLWHIAPSKTLNFSSGATHSESNAKK 279
                             99*********9998888888777666666544 PP

>> tr|B3S5V8|B3S5V8_TRIAD  Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_64190 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.7   0.0   4.4e-09     1e-05      34     151 ..     146     264 ..     138     285 .. 0.72

  Alignments for each domain:
  == domain 1  score: 24.7 bits;  conditional E-value: 4.4e-09
                   GCD14  34 mkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtvthrDvc.keGfdeevsgkvDavfL 119
                              k+++kpG++v+  G+ sg+  + ++  v+P G ++++ef ++  +  + +  +++  +++ +   D+   + + + + g vD +f 
  tr|B3S5V8|B3S5V8_TRIAD 146 DKIHIKPGAKVLYLGAASGTTVSHVSDIVGPNGLVYAVEFSHRSGRD-LINVAKKRT-NIIPI-IEDARhPHKY-RMLVGMVDVIFA 228
                             5789************************************7544433.333333332.33333.4455524555.5677******** PP

                   GCD14 120 DlPaPwea..ip.haakalkkeggrlCsf.sPCieq 151
                             D+ +P++   +  +a + lk+eg  + s  + Ci+ 
  tr|B3S5V8|B3S5V8_TRIAD 229 DVAQPDQTriVAiNAHHFLKNEGHFVISIkANCIDS 264
                             *****9863222145555688887777662568875 PP

>> tr|B3RJQ6|B3RJQ6_TRIAD  Protein-L-isoaspartate O-methyltransferase OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_495
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.2   0.0   1.8e-06    0.0042      35      86 ..      73     124 ..      52     180 .. 0.80

  Alignments for each domain:
  == domain 1  score: 16.2 bits;  conditional E-value: 1.8e-06
                   GCD14  35 kLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefr 86 
                               +lk+G+ +++ G Gsg l+  +a  v+  G+++ +e+  + ++ +r++ +
  tr|B3RJQ6|B3RJQ6_TRIAD  73 ASNLKEGCTILDVGSGSGYLTACMAMMVGSSGKVYGIEHIPELISLSRNNIN 124
                             55799*********************************98777766666655 PP

>> tr|B3RRK7|B3RRK7_TRIAD  Uncharacterized protein OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_54278 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.3   0.0       0.8   1.8e+03     144     197 ..      41      96 ..      29     117 .. 0.55
   2 !   14.4   0.4   6.5e-06     0.015     149     217 ..     184     252 ..     150     273 .. 0.75

  Alignments for each domain:
  == domain 1  score: -2.3 bits;  conditional E-value: 0.8
                   GCD14 144 sfsPCieq.vqrtceaLrel.gfteietlevllrtyevrkskleeidlaekrleen 197
                             sfs  +eq +++  e   +    t  + +  l+r +++  + l+ ++  e ++e +
  tr|B3RRK7|B3RRK7_TRIAD  41 SFSLAVEQhIKKNREGYVSItLITSFKKVKCLTRDWNIVAEALKYSQKLEVNQEGK 96 
                             67777776223333332222023445566666666666666666555544333333 PP

  == domain 2  score: 14.4 bits;  conditional E-value: 6.5e-06
                   GCD14 149 ieqvqrtceaLrelgfteietlevllrtyevrkskleeidlaekrleenerkriekakrrkaskdakve 217
                              e   r++e L++ + ++++ + v l + ++++s+l++i+++e++ ++++ ++ ek k++k +k+++++
  tr|B3RRK7|B3RRK7_TRIAD 184 PEHALRCIEGLTQADRQDLDGIGVTLLNLKIKQSTLDKIKEMEAKAKSDSASQDEKEKKSKRKKKKNKR 252
                             478889**********************************99888888877777666666655444433 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (247 nodes)
Target sequences:                        11518  (5222075 residues searched)
Passed MSV filter:                       750  (0.0651155); expected 230.4 (0.02)
Passed bias filter:                      414  (0.0359437); expected 230.4 (0.02)
Passed Vit filter:                        39  (0.003386); expected 11.5 (0.001)
Passed Fwd filter:                         6  (0.000520924); expected 0.1 (1e-05)
Initial search space (Z):              11518  [actual number of targets]
Domain search space  (domZ):               5  [number of targets reported over threshold]
# CPU time: 0.15u 0.01s 00:00:00.16 Elapsed: 00:00:00.05
# Mc/sec: 25797.05
//
[ok]