# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/GCD14.hmm.txt # target sequence database: proteomes/Xenopus_tropicalis.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: GCD14 [M=247] Accession: PF08704.9 Description: tRNA methyltransferase complex GCD14 subunit Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-115 385.1 0.0 2.4e-115 384.9 0.0 1.1 1 tr|Q6DFS3|Q6DFS3_XENTR tRNA (adenine(58)-N(1))-methyltransfe 1.9e-05 24.9 0.0 2.7e-05 24.4 0.0 1.2 1 tr|Q6P623|Q6P623_XENTR Fibrillarin OS=Xenopus tropicalis OX= 0.0001 22.5 0.0 0.00014 22.1 0.0 1.2 1 tr|F7BWE4|F7BWE4_XENTR Protein-L-isoaspartate O-methyltransf 0.00077 19.6 0.0 0.0014 18.8 0.0 1.4 1 tr|F6XHA2|F6XHA2_XENTR Protein-L-isoaspartate O-methyltransf ------ inclusion threshold ------ 0.029 14.5 0.0 0.058 13.5 0.0 1.5 1 tr|F6QFT8|F6QFT8_XENTR Protein-L-isoaspartate (D-aspartate) 0.047 13.8 0.0 0.064 13.3 0.0 1.1 1 tr|Q28HI0|Q28HI0_XENTR Catechol-O-methyltransferase OS=Xenop 0.096 12.8 0.0 0.13 12.3 0.0 1.2 1 tr|Q28GN4|Q28GN4_XENTR Catechol-O-methyltransferase OS=Xenop 0.12 12.4 0.0 0.2 11.8 0.0 1.3 1 tr|F7DJS9|F7DJS9_XENTR Protein-L-isoaspartate (D-aspartate) 0.24 11.5 0.1 3.7 7.6 0.0 2.3 2 tr|F6W5Y2|F6W5Y2_XENTR Fatty acid synthase OS=Xenopus tropic Domain annotation for each sequence (and alignments): >> tr|Q6DFS3|Q6DFS3_XENTR tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A OS=Xenopus tropicalis OX= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 384.9 0.0 8.8e-119 2.4e-115 1 247 [] 64 300 .. 64 300 .. 0.99 Alignments for each domain: == domain 1 score: 384.9 bits; conditional E-value: 8.8e-119 GCD14 1 gfvyvlaptPeLWtlaLphrtqilytaDisliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefre 87 g+vy+l+ptPeLWtl+Lphrtqily++Disli+m+LelkpGsvv+esGtGsgslshai+rtvaPtGhl+t+efh+qraeka+eefr+ tr|Q6DFS3|Q6DFS3_XENTR 64 GWVYILYPTPELWTLNLPHRTQILYSTDISLITMMLELKPGSVVCESGTGSGSLSHAIIRTVAPTGHLYTVEFHQQRAEKAIEEFRQ 150 8************************************************************************************** PP GCD14 88 helsqlvtvthrDvckeGfdeevsgkvDavfLDlPaPweaiphaakalkkeggrlCsfsPCieqvqrtceaLrelgfteietlevll 174 h++++lvtv+++Dvck+Gf +v+g +DavfLD+P+Pweai+ha++a+k+eggr+CsfsPCieqvqrtc aL+e+gftei+tle+ll tr|Q6DFS3|Q6DFS3_XENTR 151 HKVDHLVTVKNQDVCKHGF--GVTGIADAVFLDIPSPWEAIGHAKSAMKSEGGRICSFSPCIEQVQRTCLALEEHGFTEINTLEILL 235 *******************..9***************************************************************** PP GCD14 175 rtyevrkskleeidlaekrleenerkriekakrrkaskdakvedkssksstevllkPvselkghtgyLtfatk 247 r+y+vr+++l+++dl+++++e+++ + ++++k+++a ++ ++ +ks+ P +e++ghtgyLtfatk tr|Q6DFS3|Q6DFS3_XENTR 236 RVYDVRTINLQVADLGRAAEEKSSLDGTDRTKQISAVQHGSALFKSGV--------PPRETVGHTGYLTFATK 300 ************************************************........99*************86 PP >> tr|Q6P623|Q6P623_XENTR Fibrillarin OS=Xenopus tropicalis OX=8364 GN=fbl PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.4 0.0 9.9e-09 2.7e-05 34 149 .. 157 273 .. 144 294 .. 0.72 Alignments for each domain: == domain 1 score: 24.4 bits; conditional E-value: 9.9e-09 GCD14 34 mkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtvthrDvc.keGfdeevsgkvDavfL 119 ++++kpG++v+ G+ sg+ + ++ v+P G ++++ef ++ + + + +++ ++++ v D+ + + + + g vD vf tr|Q6P623|Q6P623_XENTR 157 DQIHIKPGAKVLYLGAASGTTVSHVSDVVGPEGLVYAVEFSHRSGRD-LINVAKKR-TNIIPVI-EDARhPHKY-RMLVGMVDVVFA 239 5789************************************7544443.33443333.3344554.455415566.5677******** PP GCD14 120 DlPaPwea..i.phaakalkkeggrlCsf.sPCi 149 D+ +P++ + +a + lk+ g + s + Ci tr|Q6P623|Q6P623_XENTR 240 DVAQPDQTriVaLNAHNFLKNGGHFVISIkANCI 273 *****98632213555666555554444424566 PP >> tr|F7BWE4|F7BWE4_XENTR Protein-L-isoaspartate O-methyltransferase OS=Xenopus tropicalis OX=8364 GN=pcmt1 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.1 0.0 5.1e-08 0.00014 37 90 .. 112 165 .. 92 216 .. 0.84 Alignments for each domain: == domain 1 score: 22.1 bits; conditional E-value: 5.1e-08 GCD14 37 elkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehel 90 +l++G+++++ G Gsg l+ ++r v+P+G++ +++ ++ ++ ++++ ++++ tr|F7BWE4|F7BWE4_XENTR 112 QLHEGAKALDVGSGSGILTACFSRMVGPKGKVVGIDHIKELVDDSINNVKKDDT 165 6789**************************************999999998765 PP >> tr|F6XHA2|F6XHA2_XENTR Protein-L-isoaspartate O-methyltransferase OS=Xenopus tropicalis OX=8364 GN=loc100216173 PE=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.8 0.0 5.2e-07 0.0014 37 88 .. 96 147 .. 75 167 .. 0.91 Alignments for each domain: == domain 1 score: 18.8 bits; conditional E-value: 5.2e-07 GCD14 37 elkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefreh 88 +l +G+++++ G Gsg l+ +ar v+ tG++ +e+ ++ ++ a+++ +++ tr|F6XHA2|F6XHA2_XENTR 96 KLVEGAKALDVGSGSGYLTACFARMVGLTGKVVGIEHINHLVKDAVQNVKQD 147 6889*******************************************99986 PP >> tr|F6QFT8|F6QFT8_XENTR Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 OS=Xenopus tropi # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.5 0.0 2.1e-05 0.058 30 85 .. 70 125 .. 60 145 .. 0.92 Alignments for each domain: == domain 1 score: 13.5 bits; conditional E-value: 2.1e-05 GCD14 30 sliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareef 85 s ++ L+l+pG ++ G G+g ls+ + ++P G + +e h + +e a+e++ tr|F6QFT8|F6QFT8_XENTR 70 SEVMEALKLQPGLSFLNLGSGTGYLSTMVGLILGPFGINHGIELHPDVVEYAKEKL 125 568899*****************************************999999875 PP >> tr|Q28HI0|Q28HI0_XENTR Catechol-O-methyltransferase OS=Xenopus tropicalis OX=8364 GN=comt.2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 2.4e-05 0.064 43 120 .. 61 141 .. 49 151 .. 0.80 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 2.4e-05 GCD14 43 vvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtvth...rDvckeGf.deevsgkvDavfLD 120 +vve Gt g + iar ++P ++ t+e a+ ar+ + ++++ v+v + D + + +v ++ D vfLD tr|Q28HI0|Q28HI0_XENTR 61 MVVELGTYCGYSAVRIARLLKPGARILTMEMNPVHASVARQMIEFAGVNNTVHVLEgstADFIPQLKqNYGV-DTLDFVFLD 141 79**********************************************999999641114444222213344.667777777 PP >> tr|Q28GN4|Q28GN4_XENTR Catechol-O-methyltransferase OS=Xenopus tropicalis OX=8364 GN=comt PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.0 4.9e-05 0.13 40 120 .. 105 188 .. 95 214 .. 0.80 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 4.9e-05 GCD14 40 pGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtv...thrDvckeGf.deevsgkvDavfLD 120 + s ++e Gt g + i r ++P ++ft+ef + a a++ + +l + v+v ++ D+ + + ev ++ D vf+D tr|Q28GN4|Q28GN4_XENTR 105 NPSTILELGTYCGYSAVRICRLLKPGVRFFTVEFNPAYAAVAKQIIEFAGLIDKVQVlegSTGDIIPQLKkKYEV-DTLDFVFVD 188 557899*************************************99999999776666222455666443324455.566777766 PP >> tr|F7DJS9|F7DJS9_XENTR Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain-containing 2 OS=Xenopus tropi # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.0 7.3e-05 0.2 30 87 .. 70 129 .. 59 161 .. 0.80 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 7.3e-05 GCD14 30 sliimkLelkpGsvvvesGtGsgslsha..iartvaPtGhlftfefheqraekareefre 87 s ++ L+l+pG ++ G G+g ls+ ++ +P G + +e h++ +e a+e++ + tr|F7DJS9|F7DJS9_XENTR 70 SEVMEALDLQPGLSFLNLGSGTGYLSTMagLILGTGPFGTNHGVEIHADVIEYAKEKLDQ 129 567889*******9999888888888753388999**************99999887644 PP >> tr|F6W5Y2|F6W5Y2_XENTR Fatty acid synthase OS=Xenopus tropicalis OX=8364 GN=fasn PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.6 0.0 0.0014 3.7 5 55 .. 755 806 .. 753 816 .. 0.81 2 ? 1.0 0.0 0.14 3.9e+02 8 52 .. 1480 1525 .. 1476 1560 .. 0.80 Alignments for each domain: == domain 1 score: 7.6 bits; conditional E-value: 0.0014 GCD14 5 vlaptPeLWtlaLphrtqilytaDisliimkLelkpGsvvve.sGtGsgsls 55 v++ tP ++ + hr+ il ++D+ +i+m+++l p s+ e s Gs + s tr|F6W5Y2|F6W5Y2_XENTR 755 VMEQTPVIFEDVTIHRATILPKTDLGIIQMEVRLMPASKRFEvSENGSLTAS 806 78899****9999************************987773334444444 PP == domain 2 score: 1.0 bits; conditional E-value: 0.14 GCD14 8 ptPeLWtlaLphrtqilytaDisliimkLelkpG.svvvesGtGsg 52 Pe W+l ++y++ ++++ ++++G sv + sG G tr|F6W5Y2|F6W5Y2_XENTR 1480 DVPESWSLEEAASVPVVYATAYYALVVRGRIRKGeSVLIHSGSGGV 1525 67******************99999999*****9556688987643 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (247 nodes) Target sequences: 24182 (11782085 residues searched) Passed MSV filter: 1270 (0.0525184); expected 483.6 (0.02) Passed bias filter: 758 (0.0313456); expected 483.6 (0.02) Passed Vit filter: 76 (0.00314283); expected 24.2 (0.001) Passed Fwd filter: 18 (0.000744355); expected 0.2 (1e-05) Initial search space (Z): 24182 [actual number of targets] Domain search space (domZ): 9 [number of targets reported over threshold] # CPU time: 0.37u 0.01s 00:00:00.38 Elapsed: 00:00:00.11 # Mc/sec: 26456.14 // [ok]