# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/GCD14.hmm.txt
# target sequence database: proteomes/Xenopus_tropicalis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: GCD14 [M=247]
Accession: PF08704.9
Description: tRNA methyltransferase complex GCD14 subunit
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
2e-115 385.1 0.0 2.4e-115 384.9 0.0 1.1 1 tr|Q6DFS3|Q6DFS3_XENTR tRNA (adenine(58)-N(1))-methyltransfe
1.9e-05 24.9 0.0 2.7e-05 24.4 0.0 1.2 1 tr|Q6P623|Q6P623_XENTR Fibrillarin OS=Xenopus tropicalis OX=
0.0001 22.5 0.0 0.00014 22.1 0.0 1.2 1 tr|F7BWE4|F7BWE4_XENTR Protein-L-isoaspartate O-methyltransf
0.00077 19.6 0.0 0.0014 18.8 0.0 1.4 1 tr|F6XHA2|F6XHA2_XENTR Protein-L-isoaspartate O-methyltransf
------ inclusion threshold ------
0.029 14.5 0.0 0.058 13.5 0.0 1.5 1 tr|F6QFT8|F6QFT8_XENTR Protein-L-isoaspartate (D-aspartate)
0.047 13.8 0.0 0.064 13.3 0.0 1.1 1 tr|Q28HI0|Q28HI0_XENTR Catechol-O-methyltransferase OS=Xenop
0.096 12.8 0.0 0.13 12.3 0.0 1.2 1 tr|Q28GN4|Q28GN4_XENTR Catechol-O-methyltransferase OS=Xenop
0.12 12.4 0.0 0.2 11.8 0.0 1.3 1 tr|F7DJS9|F7DJS9_XENTR Protein-L-isoaspartate (D-aspartate)
0.24 11.5 0.1 3.7 7.6 0.0 2.3 2 tr|F6W5Y2|F6W5Y2_XENTR Fatty acid synthase OS=Xenopus tropic
Domain annotation for each sequence (and alignments):
>> tr|Q6DFS3|Q6DFS3_XENTR tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A OS=Xenopus tropicalis OX=
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 384.9 0.0 8.8e-119 2.4e-115 1 247 [] 64 300 .. 64 300 .. 0.99
Alignments for each domain:
== domain 1 score: 384.9 bits; conditional E-value: 8.8e-119
GCD14 1 gfvyvlaptPeLWtlaLphrtqilytaDisliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefre 87
g+vy+l+ptPeLWtl+Lphrtqily++Disli+m+LelkpGsvv+esGtGsgslshai+rtvaPtGhl+t+efh+qraeka+eefr+
tr|Q6DFS3|Q6DFS3_XENTR 64 GWVYILYPTPELWTLNLPHRTQILYSTDISLITMMLELKPGSVVCESGTGSGSLSHAIIRTVAPTGHLYTVEFHQQRAEKAIEEFRQ 150
8************************************************************************************** PP
GCD14 88 helsqlvtvthrDvckeGfdeevsgkvDavfLDlPaPweaiphaakalkkeggrlCsfsPCieqvqrtceaLrelgfteietlevll 174
h++++lvtv+++Dvck+Gf +v+g +DavfLD+P+Pweai+ha++a+k+eggr+CsfsPCieqvqrtc aL+e+gftei+tle+ll
tr|Q6DFS3|Q6DFS3_XENTR 151 HKVDHLVTVKNQDVCKHGF--GVTGIADAVFLDIPSPWEAIGHAKSAMKSEGGRICSFSPCIEQVQRTCLALEEHGFTEINTLEILL 235
*******************..9***************************************************************** PP
GCD14 175 rtyevrkskleeidlaekrleenerkriekakrrkaskdakvedkssksstevllkPvselkghtgyLtfatk 247
r+y+vr+++l+++dl+++++e+++ + ++++k+++a ++ ++ +ks+ P +e++ghtgyLtfatk
tr|Q6DFS3|Q6DFS3_XENTR 236 RVYDVRTINLQVADLGRAAEEKSSLDGTDRTKQISAVQHGSALFKSGV--------PPRETVGHTGYLTFATK 300
************************************************........99*************86 PP
>> tr|Q6P623|Q6P623_XENTR Fibrillarin OS=Xenopus tropicalis OX=8364 GN=fbl PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 24.4 0.0 9.9e-09 2.7e-05 34 149 .. 157 273 .. 144 294 .. 0.72
Alignments for each domain:
== domain 1 score: 24.4 bits; conditional E-value: 9.9e-09
GCD14 34 mkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtvthrDvc.keGfdeevsgkvDavfL 119
++++kpG++v+ G+ sg+ + ++ v+P G ++++ef ++ + + + +++ ++++ v D+ + + + + g vD vf
tr|Q6P623|Q6P623_XENTR 157 DQIHIKPGAKVLYLGAASGTTVSHVSDVVGPEGLVYAVEFSHRSGRD-LINVAKKR-TNIIPVI-EDARhPHKY-RMLVGMVDVVFA 239
5789************************************7544443.33443333.3344554.455415566.5677******** PP
GCD14 120 DlPaPwea..i.phaakalkkeggrlCsf.sPCi 149
D+ +P++ + +a + lk+ g + s + Ci
tr|Q6P623|Q6P623_XENTR 240 DVAQPDQTriVaLNAHNFLKNGGHFVISIkANCI 273
*****98632213555666555554444424566 PP
>> tr|F7BWE4|F7BWE4_XENTR Protein-L-isoaspartate O-methyltransferase OS=Xenopus tropicalis OX=8364 GN=pcmt1 PE=3 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 22.1 0.0 5.1e-08 0.00014 37 90 .. 112 165 .. 92 216 .. 0.84
Alignments for each domain:
== domain 1 score: 22.1 bits; conditional E-value: 5.1e-08
GCD14 37 elkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehel 90
+l++G+++++ G Gsg l+ ++r v+P+G++ +++ ++ ++ ++++ ++++
tr|F7BWE4|F7BWE4_XENTR 112 QLHEGAKALDVGSGSGILTACFSRMVGPKGKVVGIDHIKELVDDSINNVKKDDT 165
6789**************************************999999998765 PP
>> tr|F6XHA2|F6XHA2_XENTR Protein-L-isoaspartate O-methyltransferase OS=Xenopus tropicalis OX=8364 GN=loc100216173 PE=3
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 18.8 0.0 5.2e-07 0.0014 37 88 .. 96 147 .. 75 167 .. 0.91
Alignments for each domain:
== domain 1 score: 18.8 bits; conditional E-value: 5.2e-07
GCD14 37 elkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefreh 88
+l +G+++++ G Gsg l+ +ar v+ tG++ +e+ ++ ++ a+++ +++
tr|F6XHA2|F6XHA2_XENTR 96 KLVEGAKALDVGSGSGYLTACFARMVGLTGKVVGIEHINHLVKDAVQNVKQD 147
6889*******************************************99986 PP
>> tr|F6QFT8|F6QFT8_XENTR Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 OS=Xenopus tropi
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 13.5 0.0 2.1e-05 0.058 30 85 .. 70 125 .. 60 145 .. 0.92
Alignments for each domain:
== domain 1 score: 13.5 bits; conditional E-value: 2.1e-05
GCD14 30 sliimkLelkpGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareef 85
s ++ L+l+pG ++ G G+g ls+ + ++P G + +e h + +e a+e++
tr|F6QFT8|F6QFT8_XENTR 70 SEVMEALKLQPGLSFLNLGSGTGYLSTMVGLILGPFGINHGIELHPDVVEYAKEKL 125
568899*****************************************999999875 PP
>> tr|Q28HI0|Q28HI0_XENTR Catechol-O-methyltransferase OS=Xenopus tropicalis OX=8364 GN=comt.2 PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 13.3 0.0 2.4e-05 0.064 43 120 .. 61 141 .. 49 151 .. 0.80
Alignments for each domain:
== domain 1 score: 13.3 bits; conditional E-value: 2.4e-05
GCD14 43 vvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtvth...rDvckeGf.deevsgkvDavfLD 120
+vve Gt g + iar ++P ++ t+e a+ ar+ + ++++ v+v + D + + +v ++ D vfLD
tr|Q28HI0|Q28HI0_XENTR 61 MVVELGTYCGYSAVRIARLLKPGARILTMEMNPVHASVARQMIEFAGVNNTVHVLEgstADFIPQLKqNYGV-DTLDFVFLD 141
79**********************************************999999641114444222213344.667777777 PP
>> tr|Q28GN4|Q28GN4_XENTR Catechol-O-methyltransferase OS=Xenopus tropicalis OX=8364 GN=comt PE=2 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 12.3 0.0 4.9e-05 0.13 40 120 .. 105 188 .. 95 214 .. 0.80
Alignments for each domain:
== domain 1 score: 12.3 bits; conditional E-value: 4.9e-05
GCD14 40 pGsvvvesGtGsgslshaiartvaPtGhlftfefheqraekareefrehelsqlvtv...thrDvckeGf.deevsgkvDavfLD 120
+ s ++e Gt g + i r ++P ++ft+ef + a a++ + +l + v+v ++ D+ + + ev ++ D vf+D
tr|Q28GN4|Q28GN4_XENTR 105 NPSTILELGTYCGYSAVRICRLLKPGVRFFTVEFNPAYAAVAKQIIEFAGLIDKVQVlegSTGDIIPQLKkKYEV-DTLDFVFVD 188
557899*************************************99999999776666222455666443324455.566777766 PP
>> tr|F7DJS9|F7DJS9_XENTR Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain-containing 2 OS=Xenopus tropi
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.8 0.0 7.3e-05 0.2 30 87 .. 70 129 .. 59 161 .. 0.80
Alignments for each domain:
== domain 1 score: 11.8 bits; conditional E-value: 7.3e-05
GCD14 30 sliimkLelkpGsvvvesGtGsgslsha..iartvaPtGhlftfefheqraekareefre 87
s ++ L+l+pG ++ G G+g ls+ ++ +P G + +e h++ +e a+e++ +
tr|F7DJS9|F7DJS9_XENTR 70 SEVMEALDLQPGLSFLNLGSGTGYLSTMagLILGTGPFGTNHGVEIHADVIEYAKEKLDQ 129
567889*******9999888888888753388999**************99999887644 PP
>> tr|F6W5Y2|F6W5Y2_XENTR Fatty acid synthase OS=Xenopus tropicalis OX=8364 GN=fasn PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 7.6 0.0 0.0014 3.7 5 55 .. 755 806 .. 753 816 .. 0.81
2 ? 1.0 0.0 0.14 3.9e+02 8 52 .. 1480 1525 .. 1476 1560 .. 0.80
Alignments for each domain:
== domain 1 score: 7.6 bits; conditional E-value: 0.0014
GCD14 5 vlaptPeLWtlaLphrtqilytaDisliimkLelkpGsvvve.sGtGsgsls 55
v++ tP ++ + hr+ il ++D+ +i+m+++l p s+ e s Gs + s
tr|F6W5Y2|F6W5Y2_XENTR 755 VMEQTPVIFEDVTIHRATILPKTDLGIIQMEVRLMPASKRFEvSENGSLTAS 806
78899****9999************************987773334444444 PP
== domain 2 score: 1.0 bits; conditional E-value: 0.14
GCD14 8 ptPeLWtlaLphrtqilytaDisliimkLelkpG.svvvesGtGsg 52
Pe W+l ++y++ ++++ ++++G sv + sG G
tr|F6W5Y2|F6W5Y2_XENTR 1480 DVPESWSLEEAASVPVVYATAYYALVVRGRIRKGeSVLIHSGSGGV 1525
67******************99999999*****9556688987643 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (247 nodes)
Target sequences: 24182 (11782085 residues searched)
Passed MSV filter: 1270 (0.0525184); expected 483.6 (0.02)
Passed bias filter: 758 (0.0313456); expected 483.6 (0.02)
Passed Vit filter: 76 (0.00314283); expected 24.2 (0.001)
Passed Fwd filter: 18 (0.000744355); expected 0.2 (1e-05)
Initial search space (Z): 24182 [actual number of targets]
Domain search space (domZ): 9 [number of targets reported over threshold]
# CPU time: 0.37u 0.01s 00:00:00.38 Elapsed: 00:00:00.11
# Mc/sec: 26456.14
//
[ok]