# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/Gcd10p.hmm.txt
# target sequence database:        proteomes/Xenopus_tropicalis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       Gcd10p  [M=300]
Accession:   PF04189.12
Description: Gcd10p family
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    4.5e-66  223.4   0.3    4.5e-66  223.4   0.3    1.7  2  tr|F7CW52|F7CW52_XENTR  tRNA (adenine(58)-N(1))-methyltransfe
  ------ inclusion threshold ------
       0.51    9.8  11.1        2.4    7.6   2.1    2.2  2  tr|F6Q9Y4|F6Q9Y4_XENTR  Uncharacterized protein OS=Xenopus tr


Domain annotation for each sequence (and alignments):
>> tr|F7CW52|F7CW52_XENTR  tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 OS=Xenopus tropicalis OX
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  223.4   0.3   3.7e-70   4.5e-66       2     263 ..      16     248 ..      15     289 .. 0.90
   2 ?   -1.9   0.6      0.16     2e+03      75     107 ..     306     337 ..     253     356 .. 0.54

  Alignments for each domain:
  == domain 1  score: 223.4 bits;  conditional E-value: 3.7e-70
                  Gcd10p   2 IkpnqhvllkLpsenlkivqvkpnttisLgKfgsfplnliigrpygltfeildkreeeeksrlrvvpaaeleaeslaeeeaeeeeee 88 
                             ++++++v+lk  ++++k vqv++ +t+s++K++ ++l+++ig++yg+tfei++  + ++k+           +e++++e +e     
  tr|F7CW52|F7CW52_XENTR  16 VSEGDFVVLK-RQDVFKAVQVQRRKTVSVEKQW-IYLDNVIGKHYGTTFEICNGGNLQTKR-----------TEVTTTEMKE----- 84 
                             7899******.888*******************.*********************654333...........3333333332..... PP

                  Gcd10p  89 eeardnreiiddgarQkLtkeeIeeLKkegasagkeiIaklleshtafdqKTaFSqeKYlkrKkkKYlkrftvlpldvsllleylle 175
                              ++ dnr+i+ddg++QkLt+++Ie+LK++g++ g++i+++l+e++++f++KT+F+qeKY+k+KkkKY   +t+l+++++ l+ ++++
  tr|F7CW52|F7CW52_XENTR  85 -AGSDNRNIVDDGKSQKLTRDDIEALKEKGIK-GEAIVQQLIENSATFRDKTEFAQEKYIKKKKKKYEAVITILKPSTRILAMMYYA 169
                             .389****************************.****************************************************** PP

                  Gcd10p 176 kkdaqki.lelr.eetlglllslanvhaggryLvvDdtgGLlvaalaeRmgifessakegtitliheneqpnlsllkyfnydaaepe 260
                              ++++ki l+ +  +  +++l+l+n+hag++++v+++++GL+++a++eR+g+       g++++++++  p  ++ + f++    p+
  tr|F7CW52|F7CW52_XENTR 170 -REPGKIcLKASvYNIYAQMLTLGNIHAGSKVIVMETCAGLVLGAVMERLGG------LGSVIQMYPGGGPVRAATDSFGF----PK 245
                             .9*****4344426789***********************************......***********************....55 PP

                  Gcd10p 261 hpl 263
                             ++ 
  tr|F7CW52|F7CW52_XENTR 246 SFY 248
                             544 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 0.16
                  Gcd10p  75 eslaeeeaeeeeeeee.............ardnreiiddgarQkLt 107
                             e              +             + + +  + ++++Qk++
  tr|F7CW52|F7CW52_XENTR 306 E--------------SvmdtnaqqqqegvEGSCEGALSKEKAQKME 337
                             1..............0112221111112233333333333444443 PP

>> tr|F6Q9Y4|F6Q9Y4_XENTR  Uncharacterized protein OS=Xenopus tropicalis OX=8364 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?    7.1   1.9   0.00028       3.4      90     118 ..     178     213 ..     119     226 .. 0.76
   2 ?    7.6   2.1    0.0002       2.4      51     118 ..     231     342 ..     227     355 .. 0.77

  Alignments for each domain:
  == domain 1  score: 7.1 bits;  conditional E-value: 0.00028
                  Gcd10p  90 e......ardnreiiddga.rQkLtkeeIeeLKkeg 118
                             +       ++ r++++ +a  Qk+t+  Ie+LK+++
  tr|F6Q9Y4|F6Q9Y4_XENTR 178 KeawerrVKKLRHLLERSAsDQKMTETSIEKLKQQQ 213
                             03333447888999996655**************96 PP

  == domain 2  score: 7.6 bits;  conditional E-value: 0.0002
                  Gcd10p  51 eildkreeeeksrlrvvpaaeleaeslaeeeaeeeeeeee............................................ard 93 
                             ei++k+++ e++ l  ++ +e++a+   +++ ++ e++++                                               
  tr|F6Q9Y4|F6Q9Y4_XENTR 231 EIQEKQRTLENKILSEISGQEKKATLAFSDQITKLETRKDelsrkighieelcnmddpikvleeserelggdlmhyffkeikpiHSP 317
                             677777777777777777666666554444444444444458888888888888888999999999999999999999999997777 PP

                  Gcd10p  94 nreiiddgarQkLtkeeIeeLKkeg 118
                              r i  +++ Qk+t+  Ie+LK+++
  tr|F6Q9Y4|F6Q9Y4_XENTR 318 ARAIYRSASDQKMTETSIEKLKQQQ 342
                             899999999**************96 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (300 nodes)
Target sequences:                        24182  (11782085 residues searched)
Passed MSV filter:                      1381  (0.0571086); expected 483.6 (0.02)
Passed bias filter:                      448  (0.0185262); expected 483.6 (0.02)
Passed Vit filter:                        45  (0.00186089); expected 24.2 (0.001)
Passed Fwd filter:                         2  (8.27061e-05); expected 0.2 (1e-05)
Initial search space (Z):              24182  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.30u 0.01s 00:00:00.31 Elapsed: 00:00:00.12
# Mc/sec: 29455.21
//
[ok]