# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/Gcd10p.hmm.txt # target sequence database: proteomes/Xenopus_tropicalis.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: Gcd10p [M=300] Accession: PF04189.12 Description: Gcd10p family Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 4.5e-66 223.4 0.3 4.5e-66 223.4 0.3 1.7 2 tr|F7CW52|F7CW52_XENTR tRNA (adenine(58)-N(1))-methyltransfe ------ inclusion threshold ------ 0.51 9.8 11.1 2.4 7.6 2.1 2.2 2 tr|F6Q9Y4|F6Q9Y4_XENTR Uncharacterized protein OS=Xenopus tr Domain annotation for each sequence (and alignments): >> tr|F7CW52|F7CW52_XENTR tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 OS=Xenopus tropicalis OX # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 223.4 0.3 3.7e-70 4.5e-66 2 263 .. 16 248 .. 15 289 .. 0.90 2 ? -1.9 0.6 0.16 2e+03 75 107 .. 306 337 .. 253 356 .. 0.54 Alignments for each domain: == domain 1 score: 223.4 bits; conditional E-value: 3.7e-70 Gcd10p 2 IkpnqhvllkLpsenlkivqvkpnttisLgKfgsfplnliigrpygltfeildkreeeeksrlrvvpaaeleaeslaeeeaeeeeee 88 ++++++v+lk ++++k vqv++ +t+s++K++ ++l+++ig++yg+tfei++ + ++k+ +e++++e +e tr|F7CW52|F7CW52_XENTR 16 VSEGDFVVLK-RQDVFKAVQVQRRKTVSVEKQW-IYLDNVIGKHYGTTFEICNGGNLQTKR-----------TEVTTTEMKE----- 84 7899******.888*******************.*********************654333...........3333333332..... PP Gcd10p 89 eeardnreiiddgarQkLtkeeIeeLKkegasagkeiIaklleshtafdqKTaFSqeKYlkrKkkKYlkrftvlpldvsllleylle 175 ++ dnr+i+ddg++QkLt+++Ie+LK++g++ g++i+++l+e++++f++KT+F+qeKY+k+KkkKY +t+l+++++ l+ ++++ tr|F7CW52|F7CW52_XENTR 85 -AGSDNRNIVDDGKSQKLTRDDIEALKEKGIK-GEAIVQQLIENSATFRDKTEFAQEKYIKKKKKKYEAVITILKPSTRILAMMYYA 169 .389****************************.****************************************************** PP Gcd10p 176 kkdaqki.lelr.eetlglllslanvhaggryLvvDdtgGLlvaalaeRmgifessakegtitliheneqpnlsllkyfnydaaepe 260 ++++ki l+ + + +++l+l+n+hag++++v+++++GL+++a++eR+g+ g++++++++ p ++ + f++ p+ tr|F7CW52|F7CW52_XENTR 170 -REPGKIcLKASvYNIYAQMLTLGNIHAGSKVIVMETCAGLVLGAVMERLGG------LGSVIQMYPGGGPVRAATDSFGF----PK 245 .9*****4344426789***********************************......***********************....55 PP Gcd10p 261 hpl 263 ++ tr|F7CW52|F7CW52_XENTR 246 SFY 248 544 PP == domain 2 score: -1.9 bits; conditional E-value: 0.16 Gcd10p 75 eslaeeeaeeeeeeee.............ardnreiiddgarQkLt 107 e + + + + + ++++Qk++ tr|F7CW52|F7CW52_XENTR 306 E--------------SvmdtnaqqqqegvEGSCEGALSKEKAQKME 337 1..............0112221111112233333333333444443 PP >> tr|F6Q9Y4|F6Q9Y4_XENTR Uncharacterized protein OS=Xenopus tropicalis OX=8364 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 7.1 1.9 0.00028 3.4 90 118 .. 178 213 .. 119 226 .. 0.76 2 ? 7.6 2.1 0.0002 2.4 51 118 .. 231 342 .. 227 355 .. 0.77 Alignments for each domain: == domain 1 score: 7.1 bits; conditional E-value: 0.00028 Gcd10p 90 e......ardnreiiddga.rQkLtkeeIeeLKkeg 118 + ++ r++++ +a Qk+t+ Ie+LK+++ tr|F6Q9Y4|F6Q9Y4_XENTR 178 KeawerrVKKLRHLLERSAsDQKMTETSIEKLKQQQ 213 03333447888999996655**************96 PP == domain 2 score: 7.6 bits; conditional E-value: 0.0002 Gcd10p 51 eildkreeeeksrlrvvpaaeleaeslaeeeaeeeeeeee............................................ard 93 ei++k+++ e++ l ++ +e++a+ +++ ++ e++++ tr|F6Q9Y4|F6Q9Y4_XENTR 231 EIQEKQRTLENKILSEISGQEKKATLAFSDQITKLETRKDelsrkighieelcnmddpikvleeserelggdlmhyffkeikpiHSP 317 677777777777777777666666554444444444444458888888888888888999999999999999999999999997777 PP Gcd10p 94 nreiiddgarQkLtkeeIeeLKkeg 118 r i +++ Qk+t+ Ie+LK+++ tr|F6Q9Y4|F6Q9Y4_XENTR 318 ARAIYRSASDQKMTETSIEKLKQQQ 342 899999999**************96 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (300 nodes) Target sequences: 24182 (11782085 residues searched) Passed MSV filter: 1381 (0.0571086); expected 483.6 (0.02) Passed bias filter: 448 (0.0185262); expected 483.6 (0.02) Passed Vit filter: 45 (0.00186089); expected 24.2 (0.001) Passed Fwd filter: 2 (8.27061e-05); expected 0.2 (1e-05) Initial search space (Z): 24182 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.30u 0.01s 00:00:00.31 Elapsed: 00:00:00.12 # Mc/sec: 29455.21 // [ok]