# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/LCM.hmm.txt # target sequence database: proteomes/Amphimedon_queenslandica.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: LCM [M=188] Accession: PF04072.14 Description: Leucine carboxyl methyltransferase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-28 101.3 0.0 4.1e-28 99.9 0.0 1.7 1 tr|A0A1X7VE43|A0A1X7VE43_AMPQE Leucine carboxyl methyltransfera 6.7e-24 86.1 0.0 1e-23 85.5 0.0 1.2 1 tr|A0A1X7VU02|A0A1X7VU02_AMPQE Uncharacterized protein OS=Amphi ------ inclusion threshold ------ 0.3 12.3 0.0 0.54 11.4 0.0 1.4 1 tr|A0A1X7UQ54|A0A1X7UQ54_AMPQE Uncharacterized protein OS=Amphi Domain annotation for each sequence (and alignments): >> tr|A0A1X7VE43|A0A1X7VE43_AMPQE Leucine carboxyl methyltransferase 1 OS=Amphimedon queenslandica OX=400682 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 99.9 0.0 2.8e-32 4.1e-28 2 186 .. 14 204 .. 13 206 .. 0.94 Alignments for each domain: == domain 1 score: 99.9 bits; conditional E-value: 2.8e-32 HHHHHHHHHHHHH.H.HHTSSHTCCCCCCCHHHHHHHHCHCCCHCHHCHGCHCCCCT--HHHHHHHHHHHHHHHHHHHH CS LCM 2 lgvaaaralesrr.a.adglidDplaeslvsaaglellerkadkelekekeeekkekkapelnrgiavRtrffddllka 78 +++++ +a +s++ a ++g+++D++++ ++++a++ ++pe+ rg+++R+ + +ll + tr|A0A1X7VE43|A0A1X7VE43_AMPQE 14 VQATNDDATSSKKyAvDQGYWKDDYVQFFCRSAEK----------------------RTPEICRGYYARVLSIQKLLVK 70 788999999999966999************99944......................58******************** PP HH.HCTTESEEEEET-TT--HHHHHHHTT..TEEEEEEE-HHHHHHHHHHHHHSHHHHH.................... CS LCM 79 al.saagirqvViLGAGlDtrayRlpwla..glkvfEvDqpevlefKretlkelgaepk.................... 134 +l +++ + v++LGAG+D++ + + + +++++D+pev + K +++k+ + + + tr|A0A1X7VE43|A0A1X7VE43_AMPQE 71 FLkLTSCDCHVINLGAGFDSTYWTMRDRGltPRTYIDIDFPEVNKKKCQIIKKRKQLLEplskdsshsatpteisstel 149 **88999****************99999988889*******************9999999******************9 PP ..EECSEEE--TTS.HHHHHHHHHHTT-TTSEEEEEEESSGGGS-HHHHHHHHHH CS LCM 135 ..aelryvpvDlrd.ddwpeaLaaagfdpekptawvaeGvlvYLtpeasdallea 186 a+ ++ ++Dlr+ ++ ++L + gfd+++pt++++e+vlvY++ e+s+ ++e+ tr|A0A1X7VE43|A0A1X7VE43_AMPQE 150 hsAHYHVLSCDLRKvGELSKKLLDLGFDTNTPTFILSECVLVYMSSESSNPIIEW 204 8888889*******************************************99998 PP >> tr|A0A1X7VU02|A0A1X7VU02_AMPQE Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 85.5 0.0 6.9e-28 1e-23 43 187 .. 48 206 .. 17 207 .. 0.87 Alignments for each domain: == domain 1 score: 85.5 bits; conditional E-value: 6.9e-28 HCHHCHGCHCCCCT--HHHHHHHHHHHHHHHHHHHHHHHCTT..ESEEEEET-TT--HHHHHHHTT.......TEEEEE CS LCM 43 kelekekeeekkekkapelnrgiavRtrffddllkaalsaag..irqvViLGAGlDtrayRlpwla.......glkvfE 112 l++++ +k+ ++ap ++ g+++R ++++ l ++l + g +qv+ LGAG+Dt ++Rl+++ +++++E tr|A0A1X7VU02|A0A1X7VU02_AMPQE 48 PYLKYFTGCHKSPNRAPLIHWGYWIRYSAVNKTLIEFLTNLGnkDNQVISLGAGFDTAFFRLKSECgnvdllkKCHYYE 126 445555545678899***********************66777789*****************9988999999****** PP EE-HHHHHHHHHHHHHSHHHHH....EECSEEE--TTS.HHHHHHHHHHTT-TTSEEEEEEESSGGGS-HHHHHHHHHH CS LCM 113 vDqpevlefKretlkelgaepk....aelryvpvDlrd.ddwpeaLaaagfdpekptawvaeGvlvYLtpeasdallea 186 vD+p+v+++K++ ++ + ++ + ++++D+++ +d+++ L+ a+ d ++ t+++ae+vl Y++p+ +d+lle+ tr|A0A1X7VU02|A0A1X7VU02_AMPQE 127 VDYPSVVARKQHFIDSVPKIKElaigSNYDLIGCDITKlKDLEASLKGANVDGDTSTLLIAEVVLTYIQPKYVDKLLEW 205 **************98876655655557777**********************************************99 PP H CS LCM 187 i 187 tr|A0A1X7VU02|A0A1X7VU02_AMPQE 206 A 206 6 PP >> tr|A0A1X7UQ54|A0A1X7UQ54_AMPQE Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.0 3.7e-05 0.54 102 135 .. 64 97 .. 63 119 .. 0.88 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 3.7e-05 HHHTTTEEEEEEE-HHHHHHHHHHHHHSHHHHHE CS LCM 102 lpwlaglkvfEvDqpevlefKretlkelgaepka 135 l w ++ v+ +D+pev++fK+ ++ + +++ tr|A0A1X7UQ54|A0A1X7UQ54_AMPQE 64 LLWIENAPVVGIDRPEVCTFKQDRITCHTPNSNT 97 57899999******************99888775 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (188 nodes) Target sequences: 43435 (14716620 residues searched) Passed MSV filter: 942 (0.0216876); expected 868.7 (0.02) Passed bias filter: 725 (0.0166916); expected 868.7 (0.02) Passed Vit filter: 48 (0.0011051); expected 43.4 (0.001) Passed Fwd filter: 3 (6.90687e-05); expected 0.4 (1e-05) Initial search space (Z): 43435 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.20u 0.01s 00:00:00.21 Elapsed: 00:00:00.10 # Mc/sec: 27667.25 // [ok]