# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/LCM.hmm.txt # target sequence database: proteomes/Ciona_savignyi.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: LCM [M=188] Accession: PF04072.14 Description: Leucine carboxyl methyltransferase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 5.2e-35 120.5 0.0 1.5e-34 118.9 0.0 1.8 1 tr|H2Z4V0|H2Z4V0_CIOSA Leucine carboxyl methyltransferase 1 2.1e-21 76.1 0.0 3.8e-21 75.3 0.0 1.5 1 tr|H2ZAB1|H2ZAB1_CIOSA Uncharacterized protein OS=Ciona savi Domain annotation for each sequence (and alignments): >> tr|H2Z4V0|H2Z4V0_CIOSA Leucine carboxyl methyltransferase 1 OS=Ciona savignyi OX=51511 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 118.9 0.0 2.6e-38 1.5e-34 1 188 [] 8 196 .. 8 196 .. 0.95 Alignments for each domain: == domain 1 score: 118.9 bits; conditional E-value: 2.6e-38 HHHHHHHHHHHHHH.H.HHTSSHTCCCCCCCHHHHHHHHCHCCCHCHHCHGCHCCCCT--HHHHHHHHHHHHHHHHHHHHHH.HCTT CS LCM 1 algvaaaralesrr.a.adglidDplaeslvsaaglellerkadkelekekeeekkekkapelnrgiavRtrffddllkaal.saag 84 a+++++ +a ++r a ++g+++D+++ ++v++++ +k+pe++rg+++Rt ++ +ll +++ ++ tr|H2Z4V0|H2Z4V0_CIOSA 8 AIQATCDDASLCKRyAvQRGYWEDKYIGYMVQSSTS---------------------RKQPEISRGYYARTEAIWKLLVQFVsIMEQ 73 7899**********669****************943.....................469**********************87899 PP ESEEEEET-TT--HHHHHHHTT..TEEEEEEE-HHHHHHHHHHHHHSHHHHH................EECSEEE--TTS.HHHHHH CS LCM 85 irqvViLGAGlDtrayRlpwla..glkvfEvDqpevlefKretlkelgaepk................aelryvpvDlrd.ddwpea 152 +q+V LGAGlDt+ +Rl++ +fEvD+ +v+++K++ + +++a+++ r+v++Dlrd +++++ tr|H2Z4V0|H2Z4V0_CIOSA 74 KCQIVSLGAGLDTTYWRLHEAGlvPHGYFEVDFIDVVTRKIRCIGTKPALRSclsdfetqsdksclhcGAYRLVSADLRDiLKLEDK 160 *********************999999***********************************99988557888************** PP HHHHTT-TTSEEEEEEESSGGGS-HHHHHHHHHHHH CS LCM 153 LaaagfdpekptawvaeGvlvYLtpeasdalleaia 188 L +ag+d pt+++ae+vl+Y+ p++s++l+++i+ tr|H2Z4V0|H2Z4V0_CIOSA 161 LISAGIDFRLPTLFLAECVLIYMAPDKSSNLINWIT 196 **********************************95 PP >> tr|H2ZAB1|H2ZAB1_CIOSA Uncharacterized protein OS=Ciona savignyi OX=51511 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 75.3 0.0 6.6e-25 3.8e-21 27 187 .. 8 191 .. 1 192 [. 0.84 Alignments for each domain: == domain 1 score: 75.3 bits; conditional E-value: 6.6e-25 CCCHHHHHHHHCHCCCHCHHCHGCHCCCCT--HHHHHHHHHHHHHHHHHHHHHH.HCTT..ESEEEEET-TT--HHHHHHHTT.... CS LCM 27 slvsaaglellerkadkelekekeeekkekkapelnrgiavRtrffddllkaal.saag..irqvViLGAGlDtrayRlpwla.... 106 s+vs+ ++ l+ ++d+ l+++ kk +++ +nrg+++R ++++ +++ +l s+ ++q++ +GAG+Dtr + ++ tr|H2ZAB1|H2ZAB1_CIOSA 8 SIVSKLSMSNLNYIEDQYLKYF---VKKPQRSALINRGYYLRSKAIEYVVQLFLlSELDsnVKQIISIGAGFDTRYFWAKDFFnryq 91 5666666665566666666665...478899*****************9999987643366**************996666655666 PP ...TEEEEEEE-HHHHHHHHHHHHHSHHHHH..............EECSEEE--TTS..HHHHHHHHHHTT-TTSEEEEEEESSGGG CS LCM 107 ...glkvfEvDqpevlefKretlkelgaepk..............aelryvpvDlrd..ddwpeaLaaagfdpekptawvaeGvlvY 174 +lk++E+D+p v+++K ++ e g ++ ++ ++ Dlr+ ++++ L++ +d ++pt++++e+vl+Y tr|H2ZAB1|H2ZAB1_CIOSA 92 dkqKLKYVEIDFPGVMNRKVNLGSEFGLYQStsinknghnvicktDDYAAIGYDLRTigPQLRDLLTEVEIDFTQPTLFISEVVLAY 178 666******************999999888899******99986556666*******99999************************* PP S-HHHHHHHHHHH CS LCM 175 Ltpeasdalleai 187 Lt +s+++l++i tr|H2ZAB1|H2ZAB1_CIOSA 179 LTGSQSSRVLSWI 191 ***********98 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (188 nodes) Target sequences: 11592 (4231397 residues searched) Passed MSV filter: 307 (0.0264838); expected 231.8 (0.02) Passed bias filter: 227 (0.0195825); expected 231.8 (0.02) Passed Vit filter: 15 (0.001294); expected 11.6 (0.001) Passed Fwd filter: 2 (0.000172533); expected 0.1 (1e-05) Initial search space (Z): 11592 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.08u 0.01s 00:00:00.09 Elapsed: 00:00:00.05 # Mc/sec: 15910.05 // [ok]