# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/LCM.hmm.txt
# target sequence database:        proteomes/Dictyostelium_discoideum.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       LCM  [M=188]
Accession:   PF04072.14
Description: Leucine carboxyl methyltransferase
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    3.8e-29  101.5   0.3    4.6e-28   97.9   0.0    2.4  2  tr|Q54NV3|Q54NV3_DICDI  Uncharacterized protein OS=Dictyostel
      5e-22   78.3   0.0    2.5e-21   76.0   0.0    2.0  1  tr|Q54J74|Q54J74_DICDI  Leucine carboxyl methyltransferase 1 


Domain annotation for each sequence (and alignments):
>> tr|Q54NV3|Q54NV3_DICDI  Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0218658 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -0.3   1.0     0.097   6.2e+02      16      47 ..      55      86 ..      37     125 .. 0.57
   2 !   97.9   0.0   7.3e-32   4.6e-28      19     187 ..     195     415 ..     187     416 .. 0.82

  Alignments for each domain:
  == domain 1  score: -0.3 bits;  conditional E-value: 0.097
                            HHTSSHTCCCCCCCHHHHHHHHCHCCCHCHHC CS
                     LCM 16 adglidDplaeslvsaaglellerkadkelek 47
                            +++l++ +  ++ ++a+++++++++++++ ++
  tr|Q54NV3|Q54NV3_DICDI 55 QQQLLQQQQQKQAAEAEQKRIMQQQQQQQQQQ 86
                            23333333333333333333322222222222 PP

  == domain 2  score: 97.9 bits;  conditional E-value: 7.3e-32
                             SSHTCCCCCCCHHHHHHHH...........................CHCCCHCHHCHGC........HCCCCT--HHHHHHHHHHHH CS
                     LCM  19 lidDplaeslvsaaglell...........................erkadkelekeke........eekkekkapelnrgiavRtr 70 
                              i+Dp+a  +++ ++ ++l                           +++++++++++++        +  + +k  +  + i  Rt+
  tr|Q54NV3|Q54NV3_DICDI 195 CIYDPFAIFFLDTEESKQLlldsfqlfhsvspqqqflnnssnniniNNNNNNNVTYKEFimkshpiqSWLEFQKGGNSINKIGFRTK 281
                             67777888777777777777777777888888877788777777775555555555553355653322333344445556689**** PP

                             HHHHHHHHHHHCTT...........ESEEEEET-TT--HHHHHHHTTTEEEEEEE-HHHHHHHHHHHHHSHHHHH....EECSEEE- CS
                     LCM  71 ffddllkaalsaag...........irqvViLGAGlDtrayRlpwlaglkvfEvDqpevlefKretlkelgaepk....aelryvpv 142
                             ++d+++ + ls +g             qvV  G+GlD+r++Rlp  ++++vfE+D p v+++K+++l+++   +k    ++ +y++ 
  tr|Q54NV3|Q54NV3_DICDI 282 YIDQVIMDSLSIKGtvahfnasaffYTQVVFCGSGLDSRSLRLPIDKHVSVFEIDLPHVINYKKKVLEKATTIIKptsqCHINYIGG 368
                             **********87899999999999999*****************************************998777766668999**** PP

                             -TTS..HHHHHHHHHHTT-TTSEEEEEEESSGGGS-HHHHHHHHHHH CS
                     LCM 143 Dlrd..ddwpeaLaaagfdpekptawvaeGvlvYLtpeasdalleai 187
                             D+ +  d+w   L ++gf+p+  t+wv+eGvl+YLt+e++  ll  i
  tr|Q54NV3|Q54NV3_DICDI 369 DIVKegDRWIGSLLDCGFNPAMHTLWVLEGVLMYLTEEEIGTLLGSI 415
                             **99899*********************************9999766 PP

>> tr|Q54J74|Q54J74_DICDI  Leucine carboxyl methyltransferase 1 OS=Dictyostelium discoideum OX=44689 GN=DDB0219323 PE=3 
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   76.0   0.0   3.9e-25   2.5e-21       5     186 ..      51     246 ..      47     248 .. 0.88

  Alignments for each domain:
  == domain 1  score: 76.0 bits;  conditional E-value: 3.9e-25
                             HHHHHHHHHHH..HHTSSHTCCCCCCCHHHHHHHHCHCCCHCHHCHGCHCCCCT--HHHHHHHHHHHHHHHHHHHHHH.HCTT..ES CS
                     LCM   5 aaaralesrra..adglidDplaeslvsaaglellerkadkelekekeeekkekkapelnrgiavRtrffddllkaal.saag..ir 86 
                             ++ +a++++ +  + g++ Dp+++++v++                       ++++p +nrg++ R+  +++l+ ++  + +    +
  tr|Q54J74|Q54J74_DICDI  51 TNDDAASCKLSavNVGYYSDPFVKYFVKHP----------------------IRRQPLINRGFFSRVECIEQLVSQFFtQYKDinKK 115
                             666777777644677777777777777766......................4579*********************9554447789 PP

                             EEEEET-TT--HHHHHHHTT....TEEEEEEE-HHHHHHHHHHHHHSHHHHH...........................EECSEEE- CS
                     LCM  87 qvViLGAGlDtrayRlpwla....glkvfEvDqpevlefKretlkelgaepk...........................aelryvpv 142
                             q++ LG+G+Dt  +Rl   +    +  +fEvD+ +v++ K++++++++++++                           ++ r+ ++
  tr|Q54J74|Q54J74_DICDI 116 QIISLGCGFDTYYFRLMNNKdikkDFIYFEVDYDQVISNKIKIIQNHKELQSmidqewdskydtneklasmvnhqrvssKSYRLGSI 202
                             ****************99998989999***********************99********************999998778888*** PP

                             -TTSHHHHHHHHHHTT-TTSEEEEEEESSGGGS-HHHHHHHHHH CS
                     LCM 143 DlrdddwpeaLaaagfdpekptawvaeGvlvYLtpeasdallea 186
                             Dl++ + ++   +  +d ++pt++++e+vlvY++ +  + ++++
  tr|Q54J74|Q54J74_DICDI 203 DLTNLETFKIFDELEIDYNVPTLFLSECVLVYIPTKCGNDVIQW 246
                             *********************************99887777776 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (188 nodes)
Target sequences:                        12739  (6856946 residues searched)
Passed MSV filter:                       734  (0.0576183); expected 254.8 (0.02)
Passed bias filter:                      341  (0.0267682); expected 254.8 (0.02)
Passed Vit filter:                        30  (0.00235497); expected 12.7 (0.001)
Passed Fwd filter:                         2  (0.000156998); expected 0.1 (1e-05)
Initial search space (Z):              12739  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.15u 0.01s 00:00:00.16 Elapsed: 00:00:00.06
# Mc/sec: 21485.10
//
[ok]