# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/LCM.hmm.txt
# target sequence database:        proteomes/Saccharomyces_cerevisiae.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       LCM  [M=188]
Accession:   PF04072.14
Description: Leucine carboxyl methyltransferase
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence              Description
    ------- ------ -----    ------- ------ -----   ---- --  --------              -----------
      7e-39  132.2   0.0    1.1e-38  131.5   0.0    1.3  1  sp|Q08282|TYW4_YEAST   tRNA wybutosine-synthesizing protein 4
    5.6e-31  106.4   0.0      7e-31  106.1   0.0    1.1  1  sp|Q04081|LCMT1_YEAST  Leucine carboxyl methyltransferase 1 O


Domain annotation for each sequence (and alignments):
>> sp|Q08282|TYW4_YEAST  tRNA wybutosine-synthesizing protein 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  131.5   0.0   3.7e-42   1.1e-38       2     187 ..       7     242 ..       6     243 .. 0.95

  Alignments for each domain:
  == domain 1  score: 131.5 bits;  conditional E-value: 3.7e-42
                           HHHHHHHHHHHHHH..HHTSSHTCCCCCCCHHHHHHHH............CHCCCHCHHCHG.CHCCCCT--HHHHHHHHHHHHHHHHH CS
                   LCM   2 lgvaaaralesrra..adglidDplaeslvsaaglell............erkadkelekek.eeekkekkapelnrgiavRtrffddl 75 
                           ++++++++ ++rr+  ad +i++++++s++s++++ell            ++k++k le++k +++kk+k++p++nrg+++R ++++++
  sp|Q08282|TYW4_YEAST   7 IKQTNKNVKQERRKkyADLAIQGTNNSSIASKRSVELLylpklssannfqMDKNNKLLEYFKfFVPKKIKRSPCINRGYWLRLFAIRSR 95 
                           7899*********66**********************9************************99************************* PP

                           HHHHH.HCTT..ESEEEEET-TT--HHHHHHHTT.........TEEEEEEE-HHHHHHHHHHHHHSHHHHH.................. CS
                   LCM  76 lkaal.saag..irqvViLGAGlDtrayRlpwla.........glkvfEvDqpevlefKretlkelgaepk.................. 134
                           l++++ ++ +     vV+LG+G+D+++++l +++         +++++++D++++l++K+e++k++++++k                  
  sp|Q08282|TYW4_YEAST  96 LNSIIeQTPQdkKIVVVNLGCGYDPLPFQLLDTNniqsqqyhdRVSFIDIDYSDLLKIKIELIKTIPELSKiiglsedkdyvddsnvdf 184
                           *****88777764489**********************************************************************999 PP

                           .EECSE..EE--TTSHHHHHHHHHH..TT-TTSEEEEEEESSGGGS-HHHHHHHHHHH CS
                   LCM 135 .aelry..vpvDlrdddwpeaLaaa..gfdpekptawvaeGvlvYLtpeasdalleai 187
                            ++ +y   p+Dl+d++++++L ++   +dp++ +++vae+ l+Y++pe+sd+++ea+
  sp|Q08282|TYW4_YEAST 185 lTTPKYlaRPCDLNDSKMFSTLLNEcqLYDPNVVKVFVAEVSLAYMKPERSDSIIEAT 242
                           98888788**************999999***************************986 PP

>> sp|Q04081|LCMT1_YEAST  Leucine carboxyl methyltransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  106.1   0.0   2.3e-34     7e-31       2     187 ..       5     219 ..       4     220 .. 0.89

  Alignments for each domain:
  == domain 1  score: 106.1 bits;  conditional E-value: 2.3e-34
                            HHHHHHHHHHHHHH..HHTSSHTCCCCCCCHHHHHHHH..CHCCCHCHHCHG.C.....HCCCCT--HHHHHHHHHHHHHHHHHHHHH CS
                    LCM   2 lgvaaaralesrra..adglidDplaeslvsaaglell..erkadkelekek.e.....eekkekkapelnrgiavRtrffddllkaa 79 
                            ++++  +al+++ a  + g++  +  ++l  + +++++  +r++  +l+k++ +     ++++++++p +n g+++Rt  +d+++ ++
  sp|Q04081|LCMT1_YEAST   5 IQQTDYDALSCKLAaiSVGYLPSSGLQRLSVDLSKKYTewHRSYLITLKKFSrRafgkvDKAMRSSFPVMNYGTYLRTVGIDAAILEF 92 
                            68999*******9669****************99999988566666666655436777788999************************ PP

                            H.HCTTESEEEEET-TT--HHHHHHHTT.TEEEEEEE-HHHHHHHHHHHHHSHHHHH................EECSE..EE--TTSH CS
                    LCM  80 l.saagirqvViLGAGlDtrayRlpwla.glkvfEvDqpevlefKretlkelgaepk................aelry..vpvDlrdd 147
                            l +++++ qvV+LG+G D r++ l ++  +l ++++D++e +e+K+++l+e+++++                 ++ ry   ++Dl+d 
  sp|Q04081|LCMT1_YEAST  93 LvANEKV-QVVNLGCGSDLRMLPLLQMFpHLAYVDIDYNESVELKNSILRESEILRIslglskedtakspfliDQGRYklAACDLNDI 179
                            *876777.*********************************************99999**************96666666*******6 PP

                            HHHHHHHHHTT-TTSEEEEEEESSGGGS-HHHHHHHHHHH CS
                    LCM 148 dwpeaLaaagfdpekptawvaeGvlvYLtpeasdalleai 187
                            + +++L +   ++e pt++++e++l+Y+++++s+ l+++i
  sp|Q04081|LCMT1_YEAST 180 TETTRLLDVCTKREIPTIVISECLLCYMHNNESQLLINTI 219
                            6666677777999************************998 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (188 nodes)
Target sequences:                         6049  (2936363 residues searched)
Passed MSV filter:                       184  (0.0304183); expected 121.0 (0.02)
Passed bias filter:                      133  (0.0219871); expected 121.0 (0.02)
Passed Vit filter:                        11  (0.00181848); expected 6.0 (0.001)
Passed Fwd filter:                         2  (0.000330633); expected 0.1 (1e-05)
Initial search space (Z):               6049  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.06u 0.00s 00:00:00.06 Elapsed: 00:00:00.03
# Mc/sec: 18401.21
//
[ok]