# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/LCM.hmm.txt # target sequence database: proteomes/Strongylocentrotus_purpuratus.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: LCM [M=188] Accession: PF04072.14 Description: Leucine carboxyl methyltransferase Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.7e-31 110.3 0.0 6.6e-31 108.4 0.0 1.8 1 tr|W4Y578|W4Y578_STRPU Leucine carboxyl methyltransferase 1 8e-30 104.8 0.0 1.2e-29 104.3 0.0 1.2 1 tr|W4YET6|W4YET6_STRPU Uncharacterized protein OS=Strongyloc 2.1e-29 103.5 0.0 3.2e-29 102.9 0.0 1.2 1 tr|W4XPM5|W4XPM5_STRPU Uncharacterized protein OS=Strongyloc Domain annotation for each sequence (and alignments): >> tr|W4Y578|W4Y578_STRPU Leucine carboxyl methyltransferase 1 OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 108.4 0.0 7e-35 6.6e-31 1 187 [. 5 196 .. 5 197 .. 0.92 Alignments for each domain: == domain 1 score: 108.4 bits; conditional E-value: 7e-35 HHHHHHHHHHHHHH.H.HHTSSHTCCCCCCCHHHHHHHHCHCCCHCHHCHGCHCCCCT--HHHHHHHHHHHHHHHHHHHHHH.HCTT CS LCM 1 algvaaaralesrr.a.adglidDplaeslvsaaglellerkadkelekekeeekkekkapelnrgiavRtrffddllkaal.saag 84 a+++++ +a ++r a ++g+++Dp+++ lv++ ++ +ape+nrg+++Rt + +ll+++l +++ tr|W4Y578|W4Y578_STRPU 5 AVQSTNDDASMCKRfAvQQGYWKDPYIQLLVKSGQR----------------------RAPEINRGYYARTQGMHTLLAQFLqLNKK 69 7999**********66***************99944......................58**********************76788 PP ESEEEEET-TT--HHHHHHHTT..TEEEEEEE-HHHHHHHHHHHHHSHHHHH..................EECSE..EE--TTS.HH CS LCM 85 irqvViLGAGlDtrayRlpwla..glkvfEvDqpevlefKretlkelgaepk..................aelry..vpvDlrd.dd 148 ++qv++LGAG+D++++Rl++++ ++EvD+ +v ++K ++++ + +++ ++ +y Dlr+ ++ tr|W4Y578|W4Y578_STRPU 70 ACQVINLGAGFDSLFWRLKDEDllPDLYIEVDFRAVTSRKCQNVRIRPKLTQgvqetcegqsvviedaelHSPKYhiLWGDLRNvEE 156 **********************98556*****************99999999***************8884455455999******* PP HHHHHHHH.TT-TTSEEEEEEESSGGGS-HHHHHHHHHHH CS LCM 149 wpeaLaaa.gfdpekptawvaeGvlvYLtpeasdalleai 187 ++++L + g+d +kpt+++ae+vlvYL++++sd ll++i tr|W4Y578|W4Y578_STRPU 157 LEKKLSKVaGIDFSKPTFFMAECVLVYLHHDKSDPLLRWI 196 *****9877*****************************98 PP >> tr|W4YET6|W4YET6_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 104.3 0.0 1.2e-33 1.2e-29 18 187 .. 16 211 .. 6 212 .. 0.89 Alignments for each domain: == domain 1 score: 104.3 bits; conditional E-value: 1.2e-33 TSSHTCCCCCCCHHHHHHHHCHCCCHCHHCHGCHCCCCT--HHHHHHHHHHHHHHHHHHHHHHHCTT..ESEEEEET-TT--HHHHH CS LCM 18 glidDplaeslvsaaglellerkadkelekekeeekkekkapelnrgiavRtrffddllkaalsaag..irqvViLGAGlDtrayRl 102 ++++++ +s+vs+ ++++ ++++ ++++ k+++++p +nrg++vR+r++dd+lka+l++ g +q++ LGAG+D++ +Rl tr|W4YET6|W4YET6_STRPU 16 IAVQGTNDSSIVSKCSVAM--MGYFQDAYLRHFVSKTSRRSPLINRGYFVRARAIDDILKAFLKKFGdsKNQIISLGAGFDSTYFRL 100 5567777778888887775..55555555656788999*************************65666899**************** PP HHTT...TEEEEEEE-HHHHHHHHHHHHHSHHHHH......................EECSEEE--TTS.HHHHHHHHHHTT-TTSE CS LCM 103 pwla...glkvfEvDqpevlefKretlkelgaepk......................aelryvpvDlrd.ddwpeaLaaagfdpekp 163 + ++ ++EvD+p+++++K+++++++ +++ ++ ++v+vDl++ d +++ ++ g d +p tr|W4YET6|W4YET6_STRPU 101 QASGsldHTAFYEVDFPQLVKRKAALIRKKTELSDlllnpvyhdeahedsfgvcissEKYHLVGVDLKQlDALQSVFKDIGVDLVVP 187 *999999**************************99******************998778888*******999999************ PP EEEEEESSGGGS-HHHHHHHHHHH CS LCM 164 tawvaeGvlvYLtpeasdalleai 187 t++++e+v+ Y++ ++sdal+++ tr|W4YET6|W4YET6_STRPU 188 TLLLSECVITYIDTDSSDALINWA 211 *********************996 PP >> tr|W4XPM5|W4XPM5_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 102.9 0.0 3.3e-33 3.2e-29 19 187 .. 17 211 .. 6 212 .. 0.89 Alignments for each domain: == domain 1 score: 102.9 bits; conditional E-value: 3.3e-33 SSHTCCCCCCCHHHHHHHHCHCCCHCHHCHGCHCCCCT--HHHHHHHHHHHHHHHHHHHHHHHCTT..ESEEEEET-TT--HHHHHH CS LCM 19 lidDplaeslvsaaglellerkadkelekekeeekkekkapelnrgiavRtrffddllkaalsaag..irqvViLGAGlDtrayRlp 103 ++++++ +s+vs+ ++++ ++++ ++++ k+++++p +nrg++vR+r++dd+lka+l++ g +q++ LGAG+D++ +Rl+ tr|W4XPM5|W4XPM5_STRPU 17 AVQGTNDSSIVSKCSVAM--MGYFQDAYLRHFVSKTSRRSPLINRGYFVRARAIDDVLKAFLKKFGdsKNQIISLGAGFDSTYFRLQ 101 567777778888887775..55555555656788999*************************65666899***************** PP HTT...TEEEEEEE-HHHHHHHHHHHHHSHHHHH......................EECSEEE--TTS.HHHHHHHHHHTT-TTSEE CS LCM 104 wla...glkvfEvDqpevlefKretlkelgaepk......................aelryvpvDlrd.ddwpeaLaaagfdpekpt 164 ++ ++EvD+p+++++K+++++++ +++ ++ ++v+vDl++ d +++ ++ g d +pt tr|W4XPM5|W4XPM5_STRPU 102 ASGsleNTAFYEVDFPQLVKRKAALIRNKTELSDlllnpvyhddshqdsfgvcissEKYHLVGVDLKQlDALQSVFKDIGVDLVVPT 188 999999**************************99******************998778888*******999999************* PP EEEEESSGGGS-HHHHHHHHHHH CS LCM 165 awvaeGvlvYLtpeasdalleai 187 ++++e+v+ Y++ ++sdal+++ tr|W4XPM5|W4XPM5_STRPU 189 LLLSECVITYIDTDSSDALINWA 211 ********************996 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (188 nodes) Target sequences: 28594 (14266044 residues searched) Passed MSV filter: 862 (0.0301462); expected 571.9 (0.02) Passed bias filter: 592 (0.0207036); expected 571.9 (0.02) Passed Vit filter: 39 (0.00136392); expected 28.6 (0.001) Passed Fwd filter: 3 (0.000104917); expected 0.3 (1e-05) Initial search space (Z): 28594 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.25u 0.01s 00:00:00.26 Elapsed: 00:00:00.13 # Mc/sec: 20630.89 // [ok]