# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/MT-A70.hmm.txt # target sequence database: proteomes/Danio_rerio.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: MT-A70 [M=172] Accession: PF05063.13 Description: MT-A70 Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 3.8e-61 206.5 0.0 5.1e-61 206.1 0.0 1.2 1 sp|Q6NZ22|MET14_DANRE N6-adenosine-methyltransferase non-ca 1.2e-59 201.6 0.0 2.3e-59 200.7 0.0 1.5 1 sp|F1R777|MTA70_DANRE N6-adenosine-methyltransferase subuni 1.8e-39 136.0 0.0 3e-39 135.2 0.0 1.4 1 tr|E7F6U3|E7F6U3_DANRE Methyltransferase-like 4 OS=Danio rer Domain annotation for each sequence (and alignments): >> sp|Q6NZ22|MET14_DANRE N6-adenosine-methyltransferase non-catalytic subunit OS=Danio rerio OX=7955 GN=mettl14 PE=2 SV # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 206.1 0.0 6e-65 5.1e-61 1 171 [. 185 361 .. 185 362 .. 0.95 Alignments for each domain: == domain 1 score: 206.1 bits; conditional E-value: 6e-65 ECEEEE---BHHCC..HTT..--SS--B-HHHHHTS-GGGCECCEEEEEEEEETTCHHHHHHHHHHHCT-EEEEEEEEEEE-TTSCBS CS MT-A70 1 fdviiidPpweeklvarkk..elpyktlneeelkaLpipelldkrslvflWvtnrellelkrellkkWglelveeltwlkinklgepi 86 fdvi+i+Pp+ee++ r++ +++ ++n++++++L+i+e+ + rs+vflW+++ e+l+l+r +l+kWg++++e+++w+k+n +++p+ sp|Q6NZ22|MET14_DANRE 185 FDVILIEPPLEEYY--RESgiIANERFWNWDDIMKLNIEEISSIRSFVFLWCGSGEGLDLGRMCLRKWGFRRCEDICWIKTN-KNNPG 269 9*************..55544999**********************************************************.55655 PP -..BS-TTSSSBB-EEEEEEEEES---TTT.T.TB-TTSSBSEEEE..E-CTTTSS-THHHHHHHHHCTCS-EEEET--G..--TTEE CS MT-A70 87 a..tlesgavlkkskEhllvgvkgnvkrstdk.iinknvdtdliis..perehsrKPpelfellehllesarkLelFaRs..lrpgwl 167 + tl+++av++++kEh+l+g+kg+v+rstd+ +i++nvd+dlii+ pe ++++KP e+f+++eh++ ++r+L+lF+R+ +rpgwl sp|Q6NZ22|MET14_DANRE 270 KtkTLDPKAVFQRTKEHCLMGIKGTVRRSTDGdFIHANVDIDLIITeePEMGNIEKPVEIFHIIEHFCLGRRRLHLFGRDstIRPGWL 357 5569******************************************9999************************************** PP EEET CS MT-A70 168 tvGn 171 tvG+ sp|Q6NZ22|MET14_DANRE 358 TVGP 361 ***7 PP >> sp|F1R777|MTA70_DANRE N6-adenosine-methyltransferase subunit METTL3 OS=Danio rerio OX=7955 GN=mettl3 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 200.7 0.0 2.6e-63 2.3e-59 1 172 [] 393 554 .. 393 554 .. 0.98 Alignments for each domain: == domain 1 score: 200.7 bits; conditional E-value: 2.6e-63 ECEEEE---BHHCC..HTT--SS--B-HHHHHTS-GGGCECCEEEEEEEEETTCHHHHHHHHHHHCT-EEEEEEEEEEE-TTSCBS-B CS MT-A70 1 fdviiidPpweeklvarkkelpyktlneeelkaLpipelldkrslvflWvtnrellelkrellkkWglelveeltwlkinklgepiat 88 f+v+++dPpw++++ elpy+tl+++e+++L+ip l+d++ ++flWvt+r+++ + re+l+ Wg+++v+e++w+k+n+l+++i+t sp|F1R777|MTA70_DANRE 393 FAVVMADPPWDIHM-----ELPYGTLTDDEMRKLNIPILQDDG-FLFLWVTGRAMELG-RECLSLWGYDRVDEIIWVKTNQLQRIIRT 473 89************.....9*****************999999.*************9.***************************** PP S-TTSSSBB-EEEEEEEEES---TTT.TTB-TTSSBSEEEEE-CTTTSS-THHHHHHHHHCTCS-EEEET--G..--TTEEEEETT CS MT-A70 89 lesgavlkkskEhllvgvkgnvkrstdkiinknvdtdliisperehsrKPpelfellehllesarkLelFaRs..lrpgwltvGne 172 +++g++l++ kEh+lvgvkgn++ +n++ d+d+i++++r++s+KP+e++ ++e+l++++rk+elF+R ++p+w+t+Gn+ sp|F1R777|MTA70_DANRE 474 GRTGHWLNHGKEHCLVGVKGNPQ-----GFNRGLDCDVIVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPhnVQPNWITLGNQ 554 **********************8.....67899***************************************999*********97 PP >> tr|E7F6U3|E7F6U3_DANRE Methyltransferase-like 4 OS=Danio rerio OX=7955 GN=mettl4 PE=3 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 135.2 0.0 3.5e-43 3e-39 1 172 [] 235 407 .. 235 407 .. 0.92 Alignments for each domain: == domain 1 score: 135.2 bits; conditional E-value: 3.5e-43 ECEEEE---BHHCC..HTT--SS--B-HHHHHTS-GGGCECCEEEEEEEEETTCHHHH..HHHHHHHCT-EEEEEEEEEEE-TTSCB CS MT-A70 1 fdviiidPpweeklvarkkelpyktlneeelkaLpipelldkrslvflWvtnrellel..krellkkWglelveeltwlkinklgep 85 fd+i++dPpwe+k+v+r++ +y+ l +lk+Lp+p l+++++lv+ Wvtnr+++ ++el ++W +e+++e+ w+k+++ ge tr|E7F6U3|E7F6U3_DANRE 235 FDLIVLDPPWENKSVKRSN--RYSSLPSSQLKKLPVPALAAPGGLVVTWVTNRAKHRRfvREELYPHWAVEVLAEWLWVKVTRSGEF 319 89****************8..************************************99899999********************** PP S-BS-TTSSSBB-EEEEEEEEES---TTT.T.TB-TTS..SBSEEEE.E-CTTTSS-THHHHHHHHHCTCS-EEEET--G--TTEEE CS MT-A70 86 iatlesgavlkkskEhllvgvkgnvkrstdk.iinknv..dtdliis.perehsrKPpelfellehllesarkLelFaRslrpgwlt 168 +++l+s+ +kk++E l++g ++ +td + n+ d+ l++s p++ hs+KP++ l + + r+LelFaRsl+ +w + tr|E7F6U3|E7F6U3_DANRE 320 VFPLDSQ--HKKPYEVLVLGRCRSTSDHTDRcS-AVNElpDQRLLVSvPSTLHSHKPSLAAVLKPYIRREPRCLELFARSLQSDWSC 403 **99998..99*********6666667888853.344447999*9999**********99888888889999*************** PP EETT CS MT-A70 169 vGne 172 +Gne tr|E7F6U3|E7F6U3_DANRE 404 WGNE 407 **97 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (172 nodes) Target sequences: 25687 (13798380 residues searched) Passed MSV filter: 673 (0.0262); expected 513.7 (0.02) Passed bias filter: 464 (0.0180636); expected 513.7 (0.02) Passed Vit filter: 49 (0.00190758); expected 25.7 (0.001) Passed Fwd filter: 3 (0.000116791); expected 0.3 (1e-05) Initial search space (Z): 25687 [actual number of targets] Domain search space (domZ): 3 [number of targets reported over threshold] # CPU time: 0.18u 0.01s 00:00:00.19 Elapsed: 00:00:00.09 # Mc/sec: 26370.24 // [ok]