# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/MT-A70.hmm.txt
# target sequence database:        proteomes/Saccharomyces_cerevisiae.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       MT-A70  [M=172]
Accession:   PF05063.13
Description: MT-A70
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence             Description
    ------- ------ -----    ------- ------ -----   ---- --  --------             -----------
    1.3e-58  196.2   0.2    2.4e-58  195.3   0.2    1.4  1  sp|P41833|IME4_YEAST  N6-adenosine-methyltransferase IME4 OS=
    1.4e-13   49.6   0.1    2.2e-13   48.9   0.1    1.4  1  sp|P25583|KAR4_YEAST  Karyogamy protein KAR4 OS=Saccharomyces


Domain annotation for each sequence (and alignments):
>> sp|P41833|IME4_YEAST  N6-adenosine-methyltransferase IME4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !  195.3   0.2   7.9e-62   2.4e-58       1     172 []     342     504 ..     342     504 .. 0.99

  Alignments for each domain:
  == domain 1  score: 195.3 bits;  conditional E-value: 7.9e-62
                           ECEEEE---BHHCC..HTT--SS--B-HHHHHTS-GGGCECCEEEEEEEEETTCHHHHHHHHHHHCT-EEEEEEEEEEE-TTSCBS-BS CS
                MT-A70   1 fdviiidPpweeklvarkkelpyktlneeelkaLpipelldkrslvflWvtnrellelkrellkkWglelveeltwlkinklgepiatl 89 
                           f+v+i+dP+w++++     +lpy+t+n+ el+ Lp++el+d++ ++flWvt+r+++ + +e+l++Wg+++++e++w+k+n+lg++i+t+
  sp|P41833|IME4_YEAST 342 FSVVIADPAWNIHM-----NLPYGTCNDIELLGLPLHELQDEG-IIFLWVTGRAIELG-KESLNNWGYNVINEVSWIKTNQLGRTIVTG 423
                           89************.....9**********************9.***********999.****************************** PP

                           -TTSSSBB-EEEEEEEEES---TTT.TTB-TTSSBSEEEEE-CTTTSS-THHHHHHHHHC.TCS-EEEET--G..--TTEEEEETT CS
                MT-A70  90 esgavlkkskEhllvgvkgnvkrstdkiinknvdtdliisperehsrKPpelfellehll.esarkLelFaRs..lrpgwltvGne 172
                           ++g++l++skEhllvg+kgn+k     +ink++d+dli+s++re+srKP+el+ ++e+l+ ++arkLe+F+R+  +rpgw+t+Gn+
  sp|P41833|IME4_YEAST 424 RTGHWLNHSKEHLLVGLKGNPK-----WINKHIDVDLIVSMTRETSRKPDELYGIAERLAgTHARKLEIFGRDhnTRPGWFTIGNQ 504
                           *********************9.....9********************************9***********************97 PP

>> sp|P25583|KAR4_YEAST  Karyogamy protein KAR4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=KA
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   48.9   0.1   7.4e-17   2.2e-13      29     167 ..     136     289 ..     111     294 .. 0.85

  Alignments for each domain:
  == domain 1  score: 48.9 bits;  conditional E-value: 7.4e-17
                           HHHHTS-GGGCECCEEEEEEEEETTCHHHHHHHHHHH..CT..-EEEEEEEEEEE-TTSCBS-...BS-TTSSSBB-EEEEEEEEES-- CS
                MT-A70  29 eelkaLpipelldkrslvflWvtnrellelkrellkk..Wg..lelveeltwlkinklgepia...tlesgavlkkskEhllvgvkgnv 110
                           + l++Lp++ l +k +++f+W  ++++ el  +ll++  W   +++ eel ++ i k+ +p +   + + +  ++k   h+ + ++g+v
  sp|P25583|KAR4_YEAST 136 PILTQLPLDRLISKPGFLFIWANSQKINEL-TKLLNNeiWAkkFRRSEELVFVPIDKK-SPFYpglDQDDETLMEKMQWHCWMCITGTV 222
                           56899****************999999999.7777755585449************55.555546688889999*************** PP

                           -TTT.T.TB-TTSSBSEEEE.E-CTTTSS-THHHHHHHHHCTCS-EEEET.--G.......--TTEE CS
                MT-A70 111 krstdk.iinknvdtdliis.perehsrKPpelfellehllesarkLelF.aRs.......lrpgwl 167
                           +rstd+  i+ nvdtdl i  + + +   P+ l+ ++e +++ +r+L++  aR        +rpgw+
  sp|P25583|KAR4_YEAST 223 RRSTDGhLIHCNVDTDLSIEtKDTTNGAVPSHLYRIAENFSTATRRLHIIpARTgyetpvkVRPGWV 289
                           ****************9988677788899*******************8647767777777777776 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (172 nodes)
Target sequences:                         6049  (2936363 residues searched)
Passed MSV filter:                       157  (0.0259547); expected 121.0 (0.02)
Passed bias filter:                       98  (0.016201); expected 121.0 (0.02)
Passed Vit filter:                         7  (0.00115722); expected 6.0 (0.001)
Passed Fwd filter:                         2  (0.000330633); expected 0.1 (1e-05)
Initial search space (Z):               6049  [actual number of targets]
Domain search space  (domZ):               2  [number of targets reported over threshold]
# CPU time: 0.04u 0.00s 00:00:00.04 Elapsed: 00:00:00.02
# Mc/sec: 25252.72
//
[ok]