# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/MTS.hmm.txt # target sequence database: proteomes/Homo_sapiens.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: MTS [M=169] Accession: PF05175.13 Description: Methyltransferase small domain Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 1.5e-14 56.1 0.0 2e-14 55.8 0.0 1.2 1 tr|B8ZZE3|B8ZZE3_HUMAN Methyltransferase like 5, isoform CR 1.7e-14 56.0 0.0 2.4e-14 55.5 0.0 1.2 1 sp|Q9NRN9|METL5_HUMAN Methyltransferase-like protein 5 OS= 2.6e-14 55.4 0.0 3.6e-14 54.9 0.0 1.2 1 tr|B8ZZC8|B8ZZC8_HUMAN Methyltransferase-like protein 5 OS= 6.5e-14 54.1 0.0 8.9e-14 53.6 0.0 1.1 1 tr|E7EMN2|E7EMN2_HUMAN Methyltransferase-like protein 5 OS= 5.1e-12 47.9 0.0 6.8e-11 44.2 0.0 2.0 2 sp|Q9Y5R4|HEMK1_HUMAN HemK methyltransferase family member 3.1e-10 42.1 0.0 5.6e-09 38.0 0.0 2.0 2 sp|Q9Y5N5|HEMK2_HUMAN HemK methyltransferase family member 1.4e-07 33.5 0.0 2.4e-07 32.7 0.0 1.3 1 tr|K7EQA8|K7EQA8_HUMAN Histone-arginine methyltransferase C 1.7e-07 33.2 0.0 3.1e-07 32.4 0.0 1.3 1 sp|Q86X55-2|CARM1_HUMAN Isoform 2 of Histone-arginine methyl 2.2e-07 32.8 0.0 6.5e-07 31.3 0.0 1.7 1 sp|Q86X55-1|CARM1_HUMAN Isoform 1 of Histone-arginine methyl 2.4e-07 32.7 0.0 6.9e-07 31.2 0.0 1.7 1 sp|Q86X55|CARM1_HUMAN Histone-arginine methyltransferase C 3.2e-07 32.3 0.0 4.4e-07 31.9 0.0 1.1 1 tr|H7C2H9|H7C2H9_HUMAN Protein arginine N-methyltransferase 3.3e-07 32.3 0.0 1.3e-05 27.1 0.0 2.0 2 tr|H7C258|H7C258_HUMAN HemK methyltransferase family member 4.5e-07 31.8 0.0 6.5e-07 31.3 0.0 1.1 1 tr|B7U632|B7U632_HUMAN PRMT2 gamma variant OS=Homo sapiens 5.5e-07 31.5 0.0 8e-07 31.0 0.0 1.1 1 tr|A8MXR3|A8MXR3_HUMAN Protein arginine N-methyltransferase 6e-07 31.4 0.0 9.8e-07 30.7 0.0 1.2 1 tr|B7U630|B7U630_HUMAN PRMT2 alpha variant OS=Homo sapiens 6.8e-07 31.3 0.0 1e-06 30.7 0.0 1.2 1 sp|P55345-2|ANM2_HUMAN Isoform 2 of Protein arginine N-meth 7.3e-07 31.1 0.0 1.1e-06 30.5 0.0 1.2 1 tr|B7U631|B7U631_HUMAN PRMT2 beta variant OS=Homo sapiens G 7.6e-07 31.1 0.0 1.3e-06 30.3 0.0 1.3 1 sp|P55345-3|ANM2_HUMAN Isoform 3 of Protein arginine N-meth 1.1e-06 30.6 0.0 2e-06 29.7 0.0 1.3 1 sp|P55345|ANM2_HUMAN Protein arginine N-methyltransferase 3.2e-06 29.1 0.0 3.3e-05 25.7 0.0 2.0 1 sp|Q9Y5N5-2|HEMK2_HUMAN Isoform 2 of HemK methyltransferase 8.1e-06 27.7 0.0 1.6e-05 26.8 0.0 1.4 1 sp|Q9BTF0|THUM2_HUMAN THUMP domain-containing protein 2 OS 9e-06 27.6 0.0 1.5e-05 26.9 0.0 1.3 1 sp|Q8IZ69-2|TRM2A_HUMAN Isoform 2 of tRNA (uracil-5-)-methyl 1e-05 27.4 0.0 1.8e-05 26.6 0.0 1.3 1 sp|Q8IZ69|TRM2A_HUMAN tRNA (uracil-5-)-methyltransferase h 2.3e-05 26.3 0.0 3.2e-05 25.8 0.0 1.2 1 sp|Q86W50-2|MET16_HUMAN Isoform 2 of Methyltransferase-like 5.1e-05 25.2 0.0 0.00011 24.1 0.0 1.5 1 sp|Q9NZJ6|COQ3_HUMAN Hexaprenyldihydroxybenzoate methyltr 7.8e-05 24.5 0.0 0.00018 23.3 0.0 1.6 1 sp|O60678-2|ANM3_HUMAN Isoform 2 of Protein arginine N-meth 8e-05 24.5 0.1 0.00011 24.0 0.1 1.1 1 tr|E9PNR9|E9PNR9_HUMAN Protein arginine N-methyltransferase 0.00011 24.1 0.0 0.00019 23.3 0.0 1.3 1 sp|Q86W50|MET16_HUMAN Methyltransferase-like protein 16 OS 0.00011 24.0 0.0 0.00022 23.1 0.0 1.4 1 sp|O60678|ANM3_HUMAN Protein arginine N-methyltransferase 0.00012 23.9 0.0 0.00021 23.1 0.0 1.4 1 sp|Q96GJ1-3|TRM2_HUMAN Isoform 3 of tRNA (uracil(54)-C(5))- 0.00013 23.8 0.0 0.00024 23.0 0.0 1.4 1 sp|Q96GJ1-2|TRM2_HUMAN Isoform 2 of tRNA (uracil(54)-C(5))- 0.00013 23.8 0.0 0.00024 23.0 0.0 1.4 1 tr|F2Z384|F2Z384_HUMAN tRNA (uracil(54)-C(5))-methyltransfe 0.00013 23.8 0.0 0.00025 22.9 0.0 1.4 1 sp|Q96GJ1|TRM2_HUMAN tRNA (uracil(54)-C(5))-methyltransfe 0.00014 23.7 0.1 0.0002 23.2 0.1 1.2 1 tr|E9PQ98|E9PQ98_HUMAN Protein arginine N-methyltransferase 0.00014 23.7 0.1 0.00021 23.2 0.1 1.2 1 tr|E9PIX6|E9PIX6_HUMAN Protein arginine N-methyltransferase 0.00019 23.3 0.1 0.00027 22.8 0.1 1.2 1 tr|H0YDE4|H0YDE4_HUMAN Protein arginine N-methyltransferase 0.00028 22.7 0.0 0.072 14.9 0.0 2.6 2 sp|Q8N6R0-4|MET13_HUMAN Isoform 2 of Methyltransferase-like 0.00028 22.7 0.0 0.00049 21.9 0.0 1.4 1 sp|O95568|MET18_HUMAN Histidine protein methyltransferase 0.00032 22.5 0.1 0.00049 21.9 0.1 1.2 1 tr|E9PKG1|E9PKG1_HUMAN Protein arginine N-methyltransferase 0.00033 22.5 0.0 0.00058 21.7 0.0 1.3 1 sp|Q96LA8|ANM6_HUMAN Protein arginine N-methyltransferase 0.00035 22.4 0.1 0.00054 21.8 0.1 1.2 1 sp|Q99873-3|ANM1_HUMAN Isoform 3 of Protein arginine N-meth 0.00035 22.4 0.1 0.00055 21.8 0.1 1.2 1 sp|Q99873-2|ANM1_HUMAN Isoform 2 of Protein arginine N-meth 0.00036 22.4 0.0 0.083 14.7 0.0 2.6 2 tr|B4E2X3|B4E2X3_HUMAN Methyltransferase-like protein 13 OS 0.00036 22.4 0.1 0.00056 21.7 0.1 1.2 1 sp|Q99873-4|ANM1_HUMAN Isoform 4 of Protein arginine N-meth 0.00036 22.4 0.0 0.083 14.7 0.0 2.6 2 sp|Q8N6R0|MET13_HUMAN Methyltransferase-like protein 13 OS 0.00037 22.4 0.0 0.00062 21.6 0.0 1.4 1 tr|H3BQF6|H3BQF6_HUMAN Uncharacterized protein (Fragment) O 0.00038 22.3 0.1 0.00059 21.7 0.1 1.2 1 sp|Q99873|ANM1_HUMAN Protein arginine N-methyltransferase 0.00039 22.3 0.1 0.00061 21.6 0.1 1.2 1 tr|H7C2I1|H7C2I1_HUMAN Protein arginine N-methyltransferase 0.00049 21.9 0.0 0.00059 21.7 0.0 1.2 1 tr|H7C0M7|H7C0M7_HUMAN Methyltransferase-like protein 5 (Fr 0.00072 21.4 0.0 0.001 20.9 0.0 1.2 1 sp|Q8IXQ9|MET20_HUMAN Methyltransferase-like protein 20 OS 0.0009 21.1 0.0 0.0014 20.5 0.0 1.3 1 sp|Q5JPI9|MET10_HUMAN Methyltransferase-like protein 10 OS 0.0012 20.7 0.0 0.0042 18.9 0.0 1.8 1 sp|Q7L2J0|MEPCE_HUMAN 7SK snRNA methylphosphate capping en 0.0012 20.7 0.0 0.0022 19.8 0.0 1.4 1 sp|Q8TCB7-2|METL6_HUMAN Isoform 2 of Methyltransferase-like 0.0016 20.3 0.0 0.0029 19.4 0.0 1.3 1 sp|Q8TCB7|METL6_HUMAN Methyltransferase-like protein 6 OS= 0.0021 19.9 0.0 0.0043 18.9 0.0 1.4 1 sp|Q8NEC7-3|GSTCD_HUMAN Isoform 2 of Glutathione S-transfera 0.0025 19.7 0.1 0.0059 18.4 0.1 1.6 1 tr|B3KU92|B3KU92_HUMAN Putative protein arginine N-methyltr 0.0026 19.6 0.0 0.0052 18.6 0.0 1.4 1 sp|Q8NEC7|GSTCD_HUMAN Glutathione S-transferase C-terminal 0.003 19.4 0.1 0.0071 18.2 0.1 1.6 1 sp|Q6P2P2|ANM10_HUMAN Putative protein arginine N-methyltr 0.0032 19.3 0.0 0.005 18.7 0.0 1.3 1 sp|Q8WXB1|MT21A_HUMAN Protein N-lysine methyltransferase M 0.0039 19.0 0.0 0.0049 18.7 0.0 1.2 1 tr|E9PMW9|E9PMW9_HUMAN Protein arginine N-methyltransferase 0.0043 18.9 0.0 0.0057 18.5 0.0 1.2 1 tr|E9PI83|E9PI83_HUMAN Protein arginine N-methyltransferase 0.0044 18.8 0.0 0.0046 18.8 0.0 1.0 1 tr|H7C2C8|H7C2C8_HUMAN Methyltransferase-like protein 2B (F 0.0067 18.2 0.0 0.011 17.5 0.0 1.2 1 sp|Q9NR22-2|ANM8_HUMAN Isoform 2 of Protein arginine N-meth 0.0069 18.2 0.0 0.012 17.4 0.0 1.3 1 sp|Q9NR22|ANM8_HUMAN Protein arginine N-methyltransferase 0.0069 18.2 0.0 0.011 17.6 0.0 1.3 1 sp|Q96IZ6-2|MET2A_HUMAN Isoform 2 of Methyltransferase-like 0.007 18.2 0.0 0.012 17.4 0.0 1.3 1 sp|O14717-3|TRDMT_HUMAN Isoform C of tRNA (cytosine(38)-C(5) 0.0073 18.1 0.0 0.013 17.3 0.0 1.3 1 sp|O14717-2|TRDMT_HUMAN Isoform B of tRNA (cytosine(38)-C(5) 0.0087 17.9 0.0 0.015 17.1 0.0 1.3 1 sp|O14717|TRDMT_HUMAN tRNA (cytosine(38)-C(5))-methyltrans 0.0093 17.8 0.0 0.014 17.3 0.0 1.2 1 sp|Q96AZ1|MT21B_HUMAN Protein-lysine methyltransferase MET 0.0097 17.7 0.0 0.028 16.2 0.0 1.7 1 sp|Q96IZ6|MET2A_HUMAN Methyltransferase-like protein 2A OS ------ inclusion threshold ------ 0.01 17.7 0.2 0.013 17.3 0.2 1.1 1 tr|H0YFV5|H0YFV5_HUMAN Methyltransferase-like protein 5 (Fr 0.013 17.3 0.0 0.036 15.9 0.0 1.7 1 sp|Q6P1Q9|MET2B_HUMAN Methyltransferase-like protein 2B OS 0.014 17.2 0.0 4.3 9.1 0.0 2.5 2 sp|Q8N6R0-1|MET13_HUMAN Isoform 4 of Methyltransferase-like 0.015 17.1 0.0 0.04 15.7 0.0 1.6 1 sp|A8MUP2|MET12_HUMAN Methyltransferase-like protein 12, m 0.016 17.0 0.0 0.025 16.4 0.0 1.3 1 sp|Q6P1Q9-2|MET2B_HUMAN Isoform 2 of Methyltransferase-like 0.016 17.0 0.0 0.023 16.5 0.0 1.3 1 tr|B3KR61|B3KR61_HUMAN HCG1811060, isoform CRA_c OS=Homo sa 0.022 16.6 0.0 0.036 15.9 0.0 1.3 1 tr|A8MTP3|A8MTP3_HUMAN Protein arginine N-methyltransferase 0.025 16.4 0.0 0.039 15.8 0.0 1.2 1 sp|Q5TEU4|NDUF5_HUMAN NADH dehydrogenase [ubiquinone] 1 al 0.026 16.4 0.0 0.045 15.6 0.0 1.3 1 tr|B4DV00|B4DV00_HUMAN Protein arginine N-methyltransferase 0.027 16.3 0.0 0.043 15.6 0.0 1.3 1 sp|Q53H54|TYW2_HUMAN tRNA wybutosine-synthesizing protein 0.028 16.2 0.0 0.04 15.7 0.0 1.4 1 sp|Q96S19|CP013_HUMAN UPF0585 protein C16orf13 OS=Homo sap 0.029 16.2 0.0 0.043 15.6 0.0 1.3 1 tr|H3BNB2|H3BNB2_HUMAN UPF0585 protein C16orf13 (Fragment) 0.029 16.2 0.0 0.051 15.4 0.0 1.3 1 tr|B4DX49|B4DX49_HUMAN Protein arginine N-methyltransferase 0.03 16.1 0.0 0.053 15.3 0.0 1.3 1 tr|G3V5W5|G3V5W5_HUMAN Protein arginine N-methyltransferase 0.031 16.1 0.0 0.044 15.6 0.0 1.3 1 sp|Q14749|GNMT_HUMAN Glycine N-methyltransferase OS=Homo 0.031 16.1 0.0 0.038 15.8 0.0 1.2 1 sp|Q96S19-4|CP013_HUMAN Isoform 4 of UPF0585 protein C16orf1 0.033 16.0 0.0 0.057 15.2 0.0 1.3 1 sp|O14744-2|ANM5_HUMAN Isoform 2 of Protein arginine N-meth 0.034 16.0 0.0 0.059 15.2 0.0 1.3 1 sp|O14744|ANM5_HUMAN Protein arginine N-methyltransferase 0.038 15.8 0.0 0.048 15.5 0.0 1.1 1 tr|H3BQ55|H3BQ55_HUMAN UPF0585 protein C16orf13 (Fragment) 0.039 15.8 0.0 0.049 15.4 0.0 1.1 1 sp|Q96S19-6|CP013_HUMAN Isoform 6 of UPF0585 protein C16orf1 0.048 15.5 0.0 0.12 14.2 0.0 1.6 1 tr|K7ES84|K7ES84_HUMAN Protein FAM86A OS=Homo sapiens GN=FA 0.054 15.3 0.0 0.16 13.8 0.0 1.7 1 sp|Q9HBK9|AS3MT_HUMAN Arsenite methyltransferase OS=Homo s 0.059 15.2 0.0 0.14 13.9 0.0 1.6 1 sp|Q96G04-2|FA86A_HUMAN Isoform 2 of Protein FAM86A OS=Homo 0.063 15.1 0.0 0.29 12.9 0.0 2.0 1 tr|K7EP06|K7EP06_HUMAN mRNA cap guanine-N7 methyltransferas 0.067 15.0 0.0 0.086 14.6 0.0 1.1 1 tr|D6RCL3|D6RCL3_HUMAN Probable dimethyladenosine transfera 0.068 15.0 0.0 0.17 13.7 0.0 1.6 1 sp|Q96G04|FA86A_HUMAN Protein FAM86A OS=Homo sapiens GN=FA 0.074 14.9 0.0 0.72 11.6 0.0 2.1 2 tr|F2Z2W7|F2Z2W7_HUMAN tRNA (uracil-5-)-methyltransferase h 0.077 14.8 0.0 0.09 14.6 0.0 1.3 1 tr|H3BNT3|H3BNT3_HUMAN UPF0585 protein C16orf13 (Fragment) 0.081 14.7 0.1 3.6 9.4 0.0 3.0 3 sp|Q9BV44|THUM3_HUMAN THUMP domain-containing protein 3 OS 0.085 14.7 0.0 0.095 14.5 0.0 1.2 1 tr|H3BMF3|H3BMF3_HUMAN UPF0585 protein C16orf13 (Fragment) 0.11 14.3 0.1 0.13 14.1 0.1 1.2 1 tr|C9J0F2|C9J0F2_HUMAN Protein-L-isoaspartate(D-aspartate) 0.11 14.2 0.0 0.21 13.3 0.0 1.4 1 sp|Q8N7N1|F86B1_HUMAN Protein FAM86B1 OS=Homo sapiens GN=F 0.11 14.2 0.0 0.16 13.8 0.0 1.2 1 tr|H7C4Z8|H7C4Z8_HUMAN Methyltransferase-like protein 2B (F 0.11 14.2 0.0 0.2 13.4 0.0 1.3 1 tr|H0Y2T8|H0Y2T8_HUMAN tRNA (cytosine(38)-C(5))-methyltrans 0.12 14.2 0.0 0.25 13.1 0.0 1.5 1 sp|Q8N6F8|WBS27_HUMAN Williams-Beuren syndrome chromosomal 0.12 14.1 0.0 0.21 13.4 0.0 1.4 1 sp|Q9BV86|NTM1A_HUMAN N-terminal Xaa-Pro-Lys N-methyltrans 0.13 14.1 0.0 0.26 13.1 0.0 1.5 1 tr|E9PN63|E9PN63_HUMAN Protein FAM86B1 OS=Homo sapiens GN=F 0.13 14.1 0.0 26 6.6 0.0 2.2 2 tr|H3BN86|H3BN86_HUMAN Methyltransferase-like protein 9 (Fr 0.14 13.9 0.2 0.21 13.4 0.2 1.4 1 tr|B7Z972|B7Z972_HUMAN Protein-L-isoaspartate O-methyltrans 0.15 13.9 0.2 1.6 10.5 0.0 2.2 2 sp|Q8N6Q8|MET25_HUMAN Methyltransferase-like protein 25 OS 0.17 13.7 0.0 0.27 13.0 0.0 1.3 1 sp|Q9UNQ2|DIM1_HUMAN Probable dimethyladenosine transfera 0.17 13.6 0.0 0.69 11.7 0.0 2.0 1 sp|O43148|MCES_HUMAN mRNA cap guanine-N7 methyltransferas 0.18 13.6 0.1 0.5 12.2 0.1 1.6 1 sp|Q9BUU2|MET22_HUMAN Methyltransferase-like protein 22 OS 0.19 13.5 0.0 0.36 12.6 0.0 1.4 1 tr|E9PQV7|E9PQV7_HUMAN Protein FAM86B2 (Fragment) OS=Homo s 0.19 13.5 0.0 0.36 12.6 0.0 1.4 1 tr|H7BXI9|H7BXI9_HUMAN Protein FAM86B2 OS=Homo sapiens GN=F 0.19 13.5 0.0 0.28 13.0 0.0 1.3 1 tr|H0YIW7|H0YIW7_HUMAN Methyltransferase-like protein 25 (F 0.19 13.5 0.0 0.76 11.6 0.0 2.0 1 sp|O43148-2|MCES_HUMAN Isoform 2 of mRNA cap guanine-N7 met 0.2 13.4 0.1 0.31 12.8 0.1 1.4 1 sp|P22061|PIMT_HUMAN Protein-L-isoaspartate(D-aspartate) 0.2 13.4 0.0 0.38 12.6 0.0 1.5 1 sp|Q7Z2T5-2|TRM1L_HUMAN Isoform 2 of TRMT1-like protein OS=H 0.2 13.4 0.1 0.31 12.8 0.1 1.4 1 sp|P22061-2|PIMT_HUMAN Isoform 2 of Protein-L-isoaspartate( 0.2 13.4 0.0 0.44 12.3 0.0 1.5 1 sp|P0C5J1|F86B2_HUMAN Protein FAM86B2 OS=Homo sapiens GN=F 0.23 13.3 0.0 0.35 12.7 0.0 1.3 1 tr|F8VZA8|F8VZA8_HUMAN Methyltransferase-like protein 25 (F 0.23 13.2 0.1 0.29 12.9 0.1 1.2 1 sp|Q9H867-1|MT21D_HUMAN Isoform 1 of Protein-lysine methyltr 0.23 13.2 0.1 0.39 12.5 0.1 1.3 1 tr|H3BTF5|H3BTF5_HUMAN Methyltransferase-like protein 22 OS 0.23 13.2 0.1 3.4 9.5 0.0 2.3 2 sp|Q9NVM4-4|ANM7_HUMAN Isoform 4 of Protein arginine N-meth 0.26 13.1 0.1 3.4 9.5 0.0 2.3 2 tr|H3BNC0|H3BNC0_HUMAN Protein arginine N-methyltransferase 0.26 13.1 0.0 43 5.9 0.0 2.2 2 sp|Q9H1A3-2|METL9_HUMAN Isoform 2 of Methyltransferase-like 0.26 13.1 0.0 0.42 12.4 0.0 1.3 1 sp|P46597|ASMT_HUMAN Acetylserotonin O-methyltransferase 0.26 13.1 0.0 43 5.9 0.0 2.2 2 sp|Q9H1A3|METL9_HUMAN Methyltransferase-like protein 9 OS= 0.29 12.9 0.0 0.41 12.4 0.0 1.2 1 tr|H3BSS9|H3BSS9_HUMAN Protein arginine N-methyltransferase 0.3 12.9 0.0 0.5 12.1 0.0 1.4 1 tr|J3KP72|J3KP72_HUMAN Protein-L-isoaspartate O-methyltrans 0.3 12.9 0.0 0.51 12.1 0.0 1.4 1 tr|H7BY58|H7BY58_HUMAN Protein-L-isoaspartate O-methyltrans 0.3 12.9 0.0 3.7 9.3 0.0 2.2 2 sp|Q8TEA1|NSUN6_HUMAN Putative methyltransferase NSUN6 OS= 0.32 12.8 0.2 0.48 12.2 0.2 1.2 1 tr|I3L2J5|I3L2J5_HUMAN Methyltransferase-like protein 22 (F 0.33 12.7 0.0 0.73 11.6 0.0 1.6 1 tr|H3BPZ8|H3BPZ8_HUMAN Protein arginine N-methyltransferase 0.35 12.7 0.0 0.42 12.4 0.0 1.2 1 sp|Q9H867-5|MT21D_HUMAN Isoform 5 of Protein-lysine methyltr 0.42 12.4 0.4 1 11.1 0.1 1.8 1 sp|Q7Z2T5|TRM1L_HUMAN TRMT1-like protein OS=Homo sapiens G 0.42 12.4 0.1 0.85 11.4 0.0 1.5 1 tr|C9JH95|C9JH95_HUMAN Histone-lysine N-methyltransferase, 0.43 12.4 0.1 4.4 9.1 0.0 2.2 2 sp|Q9NVM4|ANM7_HUMAN Protein arginine N-methyltransferase 0.46 12.3 0.0 0.63 11.8 0.0 1.2 1 sp|Q9H867|MT21D_HUMAN Protein-lysine methyltransferase MET 0.5 12.1 0.0 0.83 11.4 0.0 1.2 1 sp|Q9NVM4-2|ANM7_HUMAN Isoform 2 of Protein arginine N-meth 0.51 12.1 0.0 0.65 11.8 0.0 1.2 1 tr|H3BRQ9|H3BRQ9_HUMAN Protein arginine N-methyltransferase 0.53 12.1 0.0 31 6.3 0.0 2.2 2 sp|O43159|RRP8_HUMAN Ribosomal RNA-processing protein 8 O 0.63 11.8 0.1 2.2 10.1 0.1 1.8 1 sp|Q9P272|K1456_HUMAN Putative methyltransferase KIAA1456 0.66 11.7 0.0 0.87 11.4 0.0 1.1 1 tr|B4DWM3|B4DWM3_HUMAN Williams-Beuren syndrome chromosomal 0.71 11.7 0.0 1.7 10.4 0.0 1.7 1 sp|Q9UBP6|TRMB_HUMAN tRNA (guanine-N(7)-)-methyltransfera 0.77 11.5 0.0 3.2 9.5 0.0 1.8 2 sp|Q9H825-2|METL8_HUMAN Isoform 2 of Methyltransferase-like 0.87 11.4 0.0 1.3 10.8 0.0 1.2 1 tr|G3V353|G3V353_HUMAN Methyltransferase-like protein 17, m 0.89 11.3 0.0 4.8 9.0 0.0 2.2 1 tr|E7ETE0|E7ETE0_HUMAN Methyltransferase-like protein 8 OS= 1.1 11.1 0.0 4.5 9.0 0.0 1.8 2 sp|Q9H825|METL8_HUMAN Methyltransferase-like protein 8 OS= 1.3 10.8 0.0 1.5 10.6 0.0 1.1 1 tr|F8WD87|F8WD87_HUMAN Uncharacterized methyltransferase WB Domain annotation for each sequence (and alignments): >> tr|B8ZZE3|B8ZZE3_HUMAN Methyltransferase like 5, isoform CRA_b OS=Homo sapiens GN=METTL5 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 55.8 0.0 3.3e-17 2e-14 29 126 .. 45 146 .. 35 177 .. 0.79 Alignments for each domain: == domain 1 score: 55.8 bits; conditional E-value: 3.3e-17 CC....TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-ST..TTTSTTS-EEEEEE---ST CS MTS 29 ke....lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdv..leeveekkfdlivsNPPfh 108 ++ +++ v+DlGcG Gvl++ a + + +d+d Ale+ ++n+e+ +l +++v++dv l++ k+fd++++NPPf tr|B8ZZE3|B8ZZE3_HUMAN 45 NTyddiENKVVADLGCGCGVLSIGTAMLGAGL-CVGFDIDEDALEIFNRNAEEFELTnIDMVQCDVclLSNRMSKSFDTVIMNPPFG 130 44444466779***************998885.8899*****************9999******9744688889************8 PP TTCHCHHHHHHHHHHHHH CS MTS 109 agkatelavaeeliaeAk 126 +++++ + ++++++A tr|B8ZZE3|B8ZZE3_HUMAN 131 TKNNK--GTDMAFLKTAL 146 77653..33334444443 PP >> sp|Q9NRN9|METL5_HUMAN Methyltransferase-like protein 5 OS=Homo sapiens GN=METTL5 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 55.5 0.0 4.1e-17 2.4e-14 30 126 .. 46 146 .. 36 177 .. 0.79 Alignments for each domain: == domain 1 score: 55.5 bits; conditional E-value: 4.1e-17 C....TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-ST..TTTSTTS-EEEEEE---STTT CS MTS 30 e....lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdv..leeveekkfdlivsNPPfhag 110 + +++ v+DlGcG Gvl++ a + + +d+d Ale+ ++n+e+ +l +++v++dv l++ k+fd++++NPPf ++ sp|Q9NRN9|METL5_HUMAN 46 TyddiENKVVADLGCGCGVLSIGTAMLGAGL-CVGFDIDEDALEIFNRNAEEFELTnIDMVQCDVclLSNRMSKSFDTVIMNPPFGTK 132 4444466779***************998885.8899*****************9999******9744688889************877 PP CHCHHHHHHHHHHHHH CS MTS 111 katelavaeeliaeAk 126 +++ + ++++++A sp|Q9NRN9|METL5_HUMAN 133 NNK--GTDMAFLKTAL 146 653..33334444443 PP >> tr|B8ZZC8|B8ZZC8_HUMAN Methyltransferase-like protein 5 OS=Homo sapiens GN=METTL5 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 54.9 0.0 6.2e-17 3.6e-14 30 126 .. 46 146 .. 36 176 .. 0.79 Alignments for each domain: == domain 1 score: 54.9 bits; conditional E-value: 6.2e-17 C....TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-ST..TTTSTTS-EEEEEE---STT CS MTS 30 e....lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdv..leeveekkfdlivsNPPfha 109 + +++ v+DlGcG Gvl++ a + + +d+d Ale+ ++n+e+ +l +++v++dv l++ k+fd++++NPPf + tr|B8ZZC8|B8ZZC8_HUMAN 46 TyddiENKVVADLGCGCGVLSIGTAMLGAGL-CVGFDIDEDALEIFNRNAEEFELTnIDMVQCDVclLSNRMSKSFDTVIMNPPFGT 131 4444466779***************998885.8899*****************9999******9744688889************87 PP TCHCHHHHHHHHHHHHH CS MTS 110 gkatelavaeeliaeAk 126 ++++ + ++++++A tr|B8ZZC8|B8ZZC8_HUMAN 132 KNNK--GTDMAFLKTAL 146 7653..33344444443 PP >> tr|E7EMN2|E7EMN2_HUMAN Methyltransferase-like protein 5 OS=Homo sapiens GN=METTL5 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 53.6 0.0 1.5e-16 8.9e-14 29 113 .. 45 135 .. 35 141 .. 0.83 Alignments for each domain: == domain 1 score: 53.6 bits; conditional E-value: 1.5e-16 CC....TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-ST..TTTSTTS-EEEEEE---ST CS MTS 29 ke....lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdv..leeveekkfdlivsNPPfh 108 ++ +++ v+DlGcG Gvl++ a + + +d+d Ale+ ++n+e+ +l +++v++dv l++ k+fd++++NPPf tr|E7EMN2|E7EMN2_HUMAN 45 NTyddiENKVVADLGCGCGVLSIGTAMLGAGL-CVGFDIDEDALEIFNRNAEEFELTnIDMVQCDVclLSNRMSKSFDTVIMNPPFG 130 44444466779***************998885.8899*****************9999******9744688889************8 PP TTCHC CS MTS 109 agkat 113 +++++ tr|E7EMN2|E7EMN2_HUMAN 131 TKNNK 135 87764 PP >> sp|Q9Y5R4|HEMK1_HUMAN HemK methyltransferase family member 1 OS=Homo sapiens GN=HEMK1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 44.2 0.0 1.2e-13 6.8e-11 35 112 .. 163 249 .. 145 256 .. 0.85 2 ? 1.4 0.0 1.8 1e+03 110 137 .. 266 293 .. 260 302 .. 0.85 Alignments for each domain: == domain 1 score: 44.2 bits; conditional E-value: 1.2e-13 EEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTTTST.....TS-EEEEEE---..STTTCH CS MTS 35 vlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvleeve.....ekkfdlivsNPP..fhagka 112 +l +GcG G+++++l+++ p+ +v +vd+ +A+ +++en+++ +l+ + +++ d+++e + + +dlivsNPP fh++ + sp|Q9Y5R4|HEMK1_HUMAN 163 ILEVGCGSGAISLSLLSQLPQSRVIAVDKREAAISLTHENAQRLRLQdrIWIIHLDMTSERSwthlpWGPMDLIVSNPPyvFHQDME 249 899*******************************************9999999999998765221215679********55555544 PP == domain 2 score: 1.4 bits; conditional E-value: 1.8 TCHCHHHHHHHHHHHHHHHEEEEEEEEE CS MTS 110 gkatelavaeeliaeAkeaLkegGeLli 137 g ++ +++++++a A++ Lk++G++++ sp|Q9Y5R4|HEMK1_HUMAN 266 GGEEGMDIITHILALAPRLLKDSGSIFL 293 556678999***************9986 PP >> sp|Q9Y5N5|HEMK2_HUMAN HemK methyltransferase family member 2 OS=Homo sapiens GN=N6AMT1 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 38.0 0.0 9.5e-12 5.6e-09 20 108 .. 29 126 .. 16 141 .. 0.83 2 ? 2.2 0.0 1 5.9e+02 111 150 .. 145 184 .. 142 199 .. 0.85 Alignments for each domain: == domain 1 score: 38.0 bits; conditional E-value: 9.5e-12 HHHHHHHCHCC.....TCSE..EEEET-TTSHHHHHHHHHTTC.E.EEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTTST...TS CS MTS 20 sklLletlpke.....lsgk..vlDlGcGaGvlgaalakespeae.vtlvdvdarAlesakenleanklevevvasdvleeve...ek 96 + lLl++l+++ l +G+G Gv++a la++ ++ ++d++ +A +++ e+++ nk++++ v +d+++ + + sp|Q9Y5N5|HEMK2_HUMAN 29 TFLLLNALEAAaaelaG--VeiCLEVGSGSGVVSAFLASMIGPQAlYMCTDINPEAAACTLETARCNKVHIQPVITDLVKGLLprlTE 114 66899999987555321..24489**************997655538889***************************99987634459 PP -EEEEEE---ST CS MTS 97 kfdlivsNPPfh 108 k+dl+v NPP+ sp|Q9Y5N5|HEMK2_HUMAN 115 KVDLLVFNPPYV 126 **********86 PP == domain 2 score: 2.2 bits; conditional E-value: 1 CHCHHHHHHHHHHHHHHHEEEEEEEEEEEETTSCHHHHHH CS MTS 111 katelavaeeliaeAkeaLkegGeLliVanrklgyeslle 150 + +v+++++ ++ L+++G +++V+ ++ + e++l+ sp|Q9Y5N5|HEMK2_HUMAN 145 GKNGREVMDRFFPLVPDLLSPKGLFYLVTIKENNPEEILK 184 55667899999999**************999988888865 PP >> tr|K7EQA8|K7EQA8_HUMAN Histone-arginine methyltransferase CARM1 (Fragment) OS=Homo sapiens GN=CARM1 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.7 0.0 4.1e-10 2.4e-07 28 136 .. 140 245 .. 127 259 .. 0.78 Alignments for each domain: == domain 1 score: 32.7 bits; conditional E-value: 4.1e-10 HCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTTTSTTS-EEEEEE---STTTCH CS MTS 28 pkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvleeveekkfdlivsNPPfhagka 112 ++ +++ vlD+GcG G+l+ +a++ + ++ +v+++++A a+ +++n+l + v+ v e ++++d+i+s P g tr|K7EQA8|K7EQA8_HUMAN 140 TDFKDKIVLDVGCGSGILSFFAAQAGAR-KIYAVEASTMAQ-HAEVLVKSNNLTdrIVVIPGKVEEVSLPEQVDIIISEP---MGYM 221 33366679**************998887.8**********5.5666777777766888888888888889*********9...3444 PP CHHHHHHHHHHHHHHHEEEEEEEE CS MTS 113 telavaeeliaeAkeaLkegGeLl 136 ++ + e +Ak++Lk++G+++ tr|K7EQA8|K7EQA8_HUMAN 222 LFNERMLESYLHAKKYLKPSGNMF 245 444555555668999999999886 PP >> sp|Q86X55-2|CARM1_HUMAN Isoform 2 of Histone-arginine methyltransferase CARM1 OS=Homo sapiens GN=CARM1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 32.4 0.0 5.2e-10 3.1e-07 28 136 .. 181 286 .. 169 299 .. 0.78 Alignments for each domain: == domain 1 score: 32.4 bits; conditional E-value: 5.2e-10 HCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTTTSTTS-EEEEEE---STTTC CS MTS 28 pkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvleeveekkfdlivsNPPfhagk 111 ++ +++ vlD+GcG G+l+ +a++ + ++ +v+++++A a+ +++n+l + v+ v e ++++d+i+s P g sp|Q86X55-2|CARM1_HUMAN 181 TDFKDKIVLDVGCGSGILSFFAAQAGAR-KIYAVEASTMAQ-HAEVLVKSNNLTdrIVVIPGKVEEVSLPEQVDIIISEP---MGY 261 33266679**************998887.8**********5.5666777777766888888888888889*********9...344 PP HCHHHHHHHHHHHHHHHEEEEEEEE CS MTS 112 atelavaeeliaeAkeaLkegGeLl 136 ++ + e +Ak++Lk++G+++ sp|Q86X55-2|CARM1_HUMAN 262 MLFNERMLESYLHAKKYLKPSGNMF 286 4444555555667999999999886 PP >> sp|Q86X55-1|CARM1_HUMAN Isoform 1 of Histone-arginine methyltransferase CARM1 OS=Homo sapiens GN=CARM1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.3 0.0 1.1e-09 6.5e-07 28 136 .. 181 286 .. 169 298 .. 0.78 Alignments for each domain: == domain 1 score: 31.3 bits; conditional E-value: 1.1e-09 HCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTTTSTTS-EEEEEE---STTTC CS MTS 28 pkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvleeveekkfdlivsNPPfhagk 111 ++ +++ vlD+GcG G+l+ +a++ + ++ +v+++++A a+ +++n+l + v+ v e ++++d+i+s P g sp|Q86X55-1|CARM1_HUMAN 181 TDFKDKIVLDVGCGSGILSFFAAQAGAR-KIYAVEASTMAQ-HAEVLVKSNNLTdrIVVIPGKVEEVSLPEQVDIIISEP---MGY 261 33266679**************998887.8**********5.5666777777766888888888888889*********9...344 PP HCHHHHHHHHHHHHHHHEEEEEEEE CS MTS 112 atelavaeeliaeAkeaLkegGeLl 136 ++ + e +Ak++Lk++G+++ sp|Q86X55-1|CARM1_HUMAN 262 MLFNERMLESYLHAKKYLKPSGNMF 286 4444555555667899999999886 PP >> sp|Q86X55|CARM1_HUMAN Histone-arginine methyltransferase CARM1 OS=Homo sapiens GN=CARM1 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.2 0.0 1.2e-09 6.9e-07 28 136 .. 181 286 .. 169 298 .. 0.78 Alignments for each domain: == domain 1 score: 31.2 bits; conditional E-value: 1.2e-09 HCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTTTSTTS-EEEEEE---STTTCHC CS MTS 28 pkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvleeveekkfdlivsNPPfhagkat 113 ++ +++ vlD+GcG G+l+ +a++ + ++ +v+++++A a+ +++n+l + v+ v e ++++d+i+s P g sp|Q86X55|CARM1_HUMAN 181 TDFKDKIVLDVGCGSGILSFFAAQAGAR-KIYAVEASTMAQ-HAEVLVKSNNLTdrIVVIPGKVEEVSLPEQVDIIISEP---MGYML 263 33266679**************998887.8**********5.5666777777766888888888888889*********9...34444 PP HHHHHHHHHHHHHHHEEEEEEEE CS MTS 114 elavaeeliaeAkeaLkegGeLl 136 ++ + e +Ak++Lk++G+++ sp|Q86X55|CARM1_HUMAN 264 FNERMLESYLHAKKYLKPSGNMF 286 44555555667899999999886 PP >> tr|H7C2H9|H7C2H9_HUMAN Protein arginine N-methyltransferase 2 (Fragment) OS=Homo sapiens GN=PRMT2 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.9 0.0 7.5e-10 4.4e-07 24 103 .. 70 150 .. 64 151 .. 0.88 Alignments for each domain: == domain 1 score: 31.9 bits; conditional E-value: 7.5e-10 HHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTTS-EEEEEE CS MTS 24 letlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdvleeveekkfdlivs 103 l++ ++ +++ +lD+GcG+G++++ +a+ +v +v+++ +A + + l++ ++ ++v+++ v + v ++k+d++vs tr|H7C2H9|H7C2H9_HUMAN 70 LQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADiITVYQQKVEDVVLPEKVDVLVS 150 444445477889****************999999************99999999888899999999999999******997 PP >> tr|H7C258|H7C258_HUMAN HemK methyltransferase family member 1 (Fragment) OS=Homo sapiens GN=HEMK1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.1 0.0 2.2e-08 1.3e-05 35 77 .. 1 43 [. 1 50 [. 0.94 2 ? 3.6 0.0 0.35 2.1e+02 110 137 .. 52 79 .. 45 90 .. 0.85 Alignments for each domain: == domain 1 score: 27.1 bits; conditional E-value: 2.2e-08 EEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHH CS MTS 35 vlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenlea 77 +l +GcG G+++++l+++ p+ +v +vd+ +A+ +++en+++ tr|H7C258|H7C258_HUMAN 1 ILEVGCGSGAISLSLLSQLPQSRVIAVDKREAAISLTHENAQS 43 689*************************************986 PP == domain 2 score: 3.6 bits; conditional E-value: 0.35 TCHCHHHHHHHHHHHHHHHEEEEEEEEE CS MTS 110 gkatelavaeeliaeAkeaLkegGeLli 137 g ++ +++++++a A++ Lk++G++++ tr|H7C258|H7C258_HUMAN 52 GGEEGMDIITHILALAPRLLKDSGSIFL 79 566778999***************9986 PP >> tr|B7U632|B7U632_HUMAN PRMT2 gamma variant OS=Homo sapiens GN=PRMT2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.3 0.0 1.1e-09 6.5e-07 24 103 .. 130 210 .. 125 211 .. 0.88 Alignments for each domain: == domain 1 score: 31.3 bits; conditional E-value: 1.1e-09 HHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTTS-EEEEEE CS MTS 24 letlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdvleeveekkfdlivs 103 l++ ++ +++ +lD+GcG+G++++ +a+ +v +v+++ +A + + l++ ++ ++v+++ v + v ++k+d++vs tr|B7U632|B7U632_HUMAN 130 LQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADiITVYQQKVEDVVLPEKVDVLVS 210 444444477889****************999999************99999999888899999999999999******997 PP >> tr|A8MXR3|A8MXR3_HUMAN Protein arginine N-methyltransferase 2 OS=Homo sapiens GN=PRMT2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.0 0.0 1.4e-09 8e-07 24 103 .. 130 210 .. 125 211 .. 0.88 Alignments for each domain: == domain 1 score: 31.0 bits; conditional E-value: 1.4e-09 HHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTTS-EEEEEE CS MTS 24 letlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdvleeveekkfdlivs 103 l++ ++ +++ +lD+GcG+G++++ +a+ +v +v+++ +A + + l++ ++ ++v+++ v + v ++k+d++vs tr|A8MXR3|A8MXR3_HUMAN 130 LQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADiITVYQQKVEDVVLPEKVDVLVS 210 444444477889****************999999************99999999888899999999999999******997 PP >> tr|B7U630|B7U630_HUMAN PRMT2 alpha variant OS=Homo sapiens GN=PRMT2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.7 0.0 1.7e-09 9.8e-07 24 103 .. 130 210 .. 125 212 .. 0.88 Alignments for each domain: == domain 1 score: 30.7 bits; conditional E-value: 1.7e-09 HHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTTS-EEEEEE CS MTS 24 letlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdvleeveekkfdlivs 103 l++ ++ +++ +lD+GcG+G++++ +a+ +v +v+++ +A + + l++ ++ ++v+++ v + v ++k+d++vs tr|B7U630|B7U630_HUMAN 130 LQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADiITVYQQKVEDVVLPEKVDVLVS 210 444444477889****************999999************99999999888899999999999999******997 PP >> sp|P55345-2|ANM2_HUMAN Isoform 2 of Protein arginine N-methyltransferase 2 OS=Homo sapiens GN=PRMT2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.7 0.0 1.7e-09 1e-06 24 103 .. 130 210 .. 125 211 .. 0.88 Alignments for each domain: == domain 1 score: 30.7 bits; conditional E-value: 1.7e-09 HHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTTS-EEEEEE CS MTS 24 letlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdvleeveekkfdlivs 103 l++ ++ +++ +lD+GcG+G++++ +a+ +v +v+++ +A + + l++ ++ ++v+++ v + v ++k+d++vs sp|P55345-2|ANM2_HUMAN 130 LQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADiITVYQQKVEDVVLPEKVDVLVS 210 444444477889****************999999************99999999888899999999999999******997 PP >> tr|B7U631|B7U631_HUMAN PRMT2 beta variant OS=Homo sapiens GN=PRMT2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.5 0.0 1.9e-09 1.1e-06 24 103 .. 130 210 .. 125 211 .. 0.88 Alignments for each domain: == domain 1 score: 30.5 bits; conditional E-value: 1.9e-09 HHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTTS-EEEEEE CS MTS 24 letlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdvleeveekkfdlivs 103 l++ ++ +++ +lD+GcG+G++++ +a+ +v +v+++ +A + + l++ ++ ++v+++ v + v ++k+d++vs tr|B7U631|B7U631_HUMAN 130 LQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADiITVYQQKVEDVVLPEKVDVLVS 210 444444477889****************999999************99999999888899999999999999******997 PP >> sp|P55345-3|ANM2_HUMAN Isoform 3 of Protein arginine N-methyltransferase 2 OS=Homo sapiens GN=PRMT2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 30.3 0.0 2.3e-09 1.3e-06 24 103 .. 130 210 .. 125 211 .. 0.88 Alignments for each domain: == domain 1 score: 30.3 bits; conditional E-value: 2.3e-09 HHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTTS-EEEEEE CS MTS 24 letlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdvleeveekkfdlivs 103 l++ ++ +++ +lD+GcG+G++++ +a+ +v +v+++ +A + + l++ ++ ++v+++ v + v ++k+d++vs sp|P55345-3|ANM2_HUMAN 130 LQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADiITVYQQKVEDVVLPEKVDVLVS 210 444444477889****************999999************99999999888899999999999999******997 PP >> sp|P55345|ANM2_HUMAN Protein arginine N-methyltransferase 2 OS=Homo sapiens GN=PRMT2 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 29.7 0.0 3.4e-09 2e-06 24 103 .. 130 210 .. 125 212 .. 0.88 Alignments for each domain: == domain 1 score: 29.7 bits; conditional E-value: 3.4e-09 HHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTTS-EEEEEE CS MTS 24 letlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdvleeveekkfdlivs 103 l++ ++ +++ +lD+GcG+G++++ +a+ +v +v+++ +A + + l++ ++ ++v+++ v + v ++k+d++vs sp|P55345|ANM2_HUMAN 130 LQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADiITVYQQKVEDVVLPEKVDVLVS 210 444444477889****************999999************99999998888899999999999999******997 PP >> sp|Q9Y5N5-2|HEMK2_HUMAN Isoform 2 of HemK methyltransferase family member 2 OS=Homo sapiens GN=N6AMT1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.7 0.0 5.7e-08 3.3e-05 20 92 .. 29 107 .. 16 168 .. 0.78 Alignments for each domain: == domain 1 score: 25.7 bits; conditional E-value: 5.7e-08 HHHHHHHCHCC.....TCSE..EEEET-TTSHHHHHHHHHTTC.E.EEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTT CS MTS 20 sklLletlpke.....lsgk..vlDlGcGaGvlgaalakespeae.vtlvdvdarAlesakenleanklevevvasdvlee 92 + lLl++l+++ l +G+G Gv++a la++ ++ ++d++ +A +++ e+++ nk++++ v +d++ sp|Q9Y5N5-2|HEMK2_HUMAN 29 TFLLLNALEAAaaelaG--VeiCLEVGSGSGVVSAFLASMIGPQAlYMCTDINPEAAACTLETARCNKVHIQPVITDLVGS 107 66899999987655321..24489**************997655538889********************99999998754 PP >> sp|Q9BTF0|THUM2_HUMAN THUMP domain-containing protein 2 OS=Homo sapiens GN=THUMPD2 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.8 0.0 2.7e-08 1.6e-05 33 140 .. 300 409 .. 289 417 .. 0.88 Alignments for each domain: == domain 1 score: 26.8 bits; conditional E-value: 2.7e-08 SEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTT.TSTTS-EEEEEE---STTTCHCHHHH CS MTS 33 gkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvle.eveekkfdlivsNPPfhagkatelav 117 vlD cG G + +++ake+p++ + dv+ l + nl+a +le +e+++ +v+e ++ +++d+i+s Pf ++ + +++ sp|Q9BTF0|THUM2_HUMAN 300 AFVLDPMCGLGTILLEAAKEWPDVYYVGADVSDSQLLGTWDNLKAAGLEdkIELLKISVIElPLPSESVDIIISDIPFGKKFKLGKDI 387 4599*********************************************999999999998356799*************99977765 PP HHHHHHHHHHHEEEEEEEEEEEE CS MTS 118 aeeliaeAkeaLkegGeLliVan 140 + +++e +++L+ gG++++ + sp|Q9BTF0|THUM2_HUMAN 388 -KSILQEMERVLHVGGTIVLLLS 409 .789*************988765 PP >> sp|Q8IZ69-2|TRM2A_HUMAN Isoform 2 of tRNA (uracil-5-)-methyltransferase homolog A OS=Homo sapiens GN=TRMT2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.9 0.0 2.6e-08 1.5e-05 30 86 .. 427 486 .. 402 510 .. 0.83 Alignments for each domain: == domain 1 score: 26.9 bits; conditional E-value: 2.6e-08 C....TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE CS MTS 30 e....lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevva 86 + vlD++cG+G +g+ala++ ++ v v+ +A+e a+ n+++n+l+ ve++ sp|Q8IZ69-2|TRM2A_HUMAN 427 WaqldAGSMVLDVCCGTGTIGLALARKVKR--VIGVELCPEAVEDARVNAQDNELSnVEFHC 486 333435667*****************9999..8999999***************99777654 PP >> sp|Q8IZ69|TRM2A_HUMAN tRNA (uracil-5-)-methyltransferase homolog A OS=Homo sapiens GN=TRMT2A PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.6 0.0 3.1e-08 1.8e-05 31 86 .. 432 486 .. 403 509 .. 0.83 Alignments for each domain: == domain 1 score: 26.6 bits; conditional E-value: 3.1e-08 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevva 86 + vlD++cG+G +g+ala++ ++ v v+ +A+e a+ n+++n+l+ ve++ sp|Q8IZ69|TRM2A_HUMAN 432 AGSMVLDVCCGTGTIGLALARKVKR--VIGVELCPEAVEDARVNAQDNELSnVEFHC 486 5667*****************9999..8999999***************99777654 PP >> sp|Q86W50-2|MET16_HUMAN Isoform 2 of Methyltransferase-like protein 16 OS=Homo sapiens GN=METTL16 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.8 0.0 5.5e-08 3.2e-05 31 112 .. 102 192 .. 92 200 .. 0.84 Alignments for each domain: == domain 1 score: 25.8 bits; conditional E-value: 5.5e-08 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.........EEEEE-STTTTSTTS-EEEEEE---S CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.........vevvasdvleeveekkfdlivsNPPf 107 + ++ +D+G+Ga + l + + +++vd + + ak+n+e+n+l+ +++ d+l+e +e +d+ ++NPPf sp|Q86W50-2|MET16_HUMAN 102 TLRRGIDIGTGASCIYPLLGATLNGWYFLATEVDDMCFNYAKKNVEQNNLSdlikvvkvpQKTLLMDALKEESEIIYDFCMCNPPF 187 55678*********************************************99977755555556678888888889********** PP TTTCH CS MTS 108 hagka 112 a++ sp|Q86W50-2|MET16_HUMAN 188 FANQL 192 98765 PP >> sp|Q9NZJ6|COQ3_HUMAN Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial OS=Homo sapiens GN=COQ3 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.1 0.0 1.9e-07 0.00011 23 154 .. 132 267 .. 129 276 .. 0.79 Alignments for each domain: == domain 1 score: 24.1 bits; conditional E-value: 1.9e-07 HHHHCHCC......TCSEEEEET-TTSHHHHHHHHHTTC.E.EEEEESBHHHHHHHHH..HHHHTTGCEEEEE.-STTTTSTTS-EEEE CS MTS 23 Lletlpke......lsgkvlDlGcGaGvlgaalakespeae.vtlvdvdarAlesake..nleanklevevva.sdvleeveekkfdli 101 Ll+t+p++ l k+lD+GcG G+l+ l + ++ ++ vd++ + ++ k + ++++e +v ++++ee++ + fd++ sp|Q9NZJ6|COQ3_HUMAN 132 LLKTIPNHqpgkplLGMKILDVGCGGGLLTEPLGRLGASVIgIDPVDENIKTAQCHKSfdPVLDKRIEYRVCSlEEIVEETA-ETFDAV 219 677777776666666778*******************99999*********9999885337888888855554155666666.9***** PP EE---STTTCHCHHHHHHHHHHHHHHHEEEEEEEEEEEETTSCHHHHHHHHHS CS MTS 102 vsNPPfhagkatelavaeeliaeAkeaLkegGeLliVanrklgyeslleelfg 154 v + + e++++ ++Lk+gG+L+i + +k + + +l +f+ sp|Q9NZJ6|COQ3_HUMAN 220 VASEVVEHVI-----DLETFLQCCCQVLKPGGSLFITTINKTQLSYALGIVFS 267 *854444443.....4899*****************99888888887777775 PP >> sp|O60678-2|ANM3_HUMAN Isoform 2 of Protein arginine N-methyltransferase 3 OS=Homo sapiens GN=PRMT3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.3 0.0 3.1e-07 0.00018 31 103 .. 193 266 .. 183 267 .. 0.80 Alignments for each domain: == domain 1 score: 23.3 bits; conditional E-value: 3.1e-07 TCSEEEEET-TTSHHHHHHHHHTTC.E..EEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTTS-EEEEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakespeae..vtlvdvdarAlesakenleankle.vevvasdvleeveekkfdlivs 103 +++ vlD+GcG+G+l++ +ak+ + v+ ++ ++A+++ + n + + ++ ++v ve k+d+i+s sp|O60678-2|ANM3_HUMAN 193 KDKVVLDVGCGTGILSMFAAKAGAKKVlgVDQSEILYQAMDIIRLNKLEDTITlIKGKIEEVHLPVE--KVDVIIS 266 45679****************9888544466667778999999999999998878888888877777..9999987 PP >> tr|E9PNR9|E9PNR9_HUMAN Protein arginine N-methyltransferase 1 (Fragment) OS=Homo sapiens GN=PRMT1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.0 0.1 1.9e-07 0.00011 31 103 .. 42 115 .. 32 116 .. 0.81 Alignments for each domain: == domain 1 score: 24.0 bits; conditional E-value: 1.9e-07 TCSEEEEET-TTSHHHHHHHHHTTC.E..EEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTTS-EEEEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakespeae..vtlvdvdarAlesakenleankle.vevvasdvleeveekkfdlivs 103 +++ vlD+G+G+G+l + +ak+ + +++ ++ +A+++ k+n ++ + ++ ++v ve k+d+i+s tr|E9PNR9|E9PNR9_HUMAN 42 KDKVVLDVGSGTGILCMFAAKAGARKVigIECSSISDYAVKIVKANKLDHVVTiIKGKVEEVELPVE--KVDIIIS 115 45679***************9987765569****************999998866666666655555..9999997 PP >> sp|Q86W50|MET16_HUMAN Methyltransferase-like protein 16 OS=Homo sapiens GN=METTL16 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.3 0.0 3.2e-07 0.00019 31 112 .. 102 192 .. 92 200 .. 0.84 Alignments for each domain: == domain 1 score: 23.3 bits; conditional E-value: 3.2e-07 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.........EEEEE-STTTTSTTS-EEEEEE---STT CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.........vevvasdvleeveekkfdlivsNPPfha 109 + ++ +D+G+Ga + l + + +++vd + + ak+n+e+n+l+ +++ d+l+e +e +d+ ++NPPf a sp|Q86W50|MET16_HUMAN 102 TLRRGIDIGTGASCIYPLLGATLNGWYFLATEVDDMCFNYAKKNVEQNNLSdlikvvkvpQKTLLMDALKEESEIIYDFCMCNPPFFA 189 45678*********************************************99977755555556678888888889**********88 PP TCH CS MTS 110 gka 112 ++ sp|Q86W50|MET16_HUMAN 190 NQL 192 764 PP >> sp|O60678|ANM3_HUMAN Protein arginine N-methyltransferase 3 OS=Homo sapiens GN=PRMT3 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.1 0.0 3.7e-07 0.00022 32 103 .. 256 328 .. 245 329 .. 0.80 Alignments for each domain: == domain 1 score: 23.1 bits; conditional E-value: 3.7e-07 CSEEEEET-TTSHHHHHHHHHTTC.E..EEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTTS-EEEEEE CS MTS 32 sgkvlDlGcGaGvlgaalakespeae..vtlvdvdarAlesakenleankle.vevvasdvleeveekkfdlivs 103 ++ vlD+GcG+G+l++ +ak+ + v+ ++ ++A+++ + n + + ++ ++v ve k+d+i+s sp|O60678|ANM3_HUMAN 256 DKVVLDVGCGTGILSMFAAKAGAKKVlgVDQSEILYQAMDIIRLNKLEDTITlIKGKIEEVHLPVE--KVDVIIS 328 5679****************9888544466667778999999999999998878888888877777..9999987 PP >> sp|Q96GJ1-3|TRM2_HUMAN Isoform 3 of tRNA (uracil(54)-C(5))-methyltransferase homolog OS=Homo sapiens GN=TRMT2B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.1 0.0 3.6e-07 0.00021 21 86 .. 285 353 .. 271 390 .. 0.79 Alignments for each domain: == domain 1 score: 23.1 bits; conditional E-value: 3.6e-07 HHHHHHCHCC....TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE CS MTS 21 klLletlpke....lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevva 86 ++L +t+ + + +lD++cG+Gv+g++la+++++ v ++ +A+e a+ +++ n++ e+++ sp|Q96GJ1-3|TRM2_HUMAN 285 EMLYRTVGELtgvnSDTILLDICCGTGVIGLSLAQHTSR--VLGIELLEQAVEDARWTAAFNGITnSEFHT 353 55555555543432334479***************9888..89999999*************998555544 PP >> sp|Q96GJ1-2|TRM2_HUMAN Isoform 2 of tRNA (uracil(54)-C(5))-methyltransferase homolog OS=Homo sapiens GN=TRMT2B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.0 0.0 4.1e-07 0.00024 21 86 .. 330 398 .. 316 435 .. 0.79 Alignments for each domain: == domain 1 score: 23.0 bits; conditional E-value: 4.1e-07 HHHHHHCHCC....TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE CS MTS 21 klLletlpke....lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevva 86 ++L +t+ + + +lD++cG+Gv+g++la+++++ v ++ +A+e a+ +++ n++ e+++ sp|Q96GJ1-2|TRM2_HUMAN 330 EMLYRTVGELtgvnSDTILLDICCGTGVIGLSLAQHTSR--VLGIELLEQAVEDARWTAAFNGITnSEFHT 398 55555555543432334479***************9888..89999999*************998555544 PP >> tr|F2Z384|F2Z384_HUMAN tRNA (uracil(54)-C(5))-methyltransferase homolog OS=Homo sapiens GN=TRMT2B PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.0 0.0 4.1e-07 0.00024 21 86 .. 330 398 .. 316 435 .. 0.79 Alignments for each domain: == domain 1 score: 23.0 bits; conditional E-value: 4.1e-07 HHHHHHCHCC....TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE CS MTS 21 klLletlpke....lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevva 86 ++L +t+ + + +lD++cG+Gv+g++la+++++ v ++ +A+e a+ +++ n++ e+++ tr|F2Z384|F2Z384_HUMAN 330 EMLYRTVGELtgvnSDTILLDICCGTGVIGLSLAQHTSR--VLGIELLEQAVEDARWTAAFNGITnSEFHT 398 55555555543432334479***************9888..89999999*************998555544 PP >> sp|Q96GJ1|TRM2_HUMAN tRNA (uracil(54)-C(5))-methyltransferase homolog OS=Homo sapiens GN=TRMT2B PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.9 0.0 4.2e-07 0.00025 21 86 .. 330 398 .. 316 435 .. 0.79 Alignments for each domain: == domain 1 score: 22.9 bits; conditional E-value: 4.2e-07 HHHHHHCHCC....TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE CS MTS 21 klLletlpke....lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevva 86 ++L +t+ + + +lD++cG+Gv+g++la+++++ v ++ +A+e a+ +++ n++ e+++ sp|Q96GJ1|TRM2_HUMAN 330 EMLYRTVGELtgvnSDTILLDICCGTGVIGLSLAQHTSR--VLGIELLEQAVEDARWTAAFNGITnSEFHT 398 55555555543432334479***************9888..89999999*************998555544 PP >> tr|E9PQ98|E9PQ98_HUMAN Protein arginine N-methyltransferase 1 (Fragment) OS=Homo sapiens GN=PRMT1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.2 0.1 3.4e-07 0.0002 31 103 .. 42 115 .. 32 116 .. 0.80 Alignments for each domain: == domain 1 score: 23.2 bits; conditional E-value: 3.4e-07 TCSEEEEET-TTSHHHHHHHHHTTC.E..EEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTTS-EEEEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakespeae..vtlvdvdarAlesakenleankle.vevvasdvleeveekkfdlivs 103 +++ vlD+G+G+G+l + +ak+ + +++ ++ +A+++ k+n ++ + ++ ++v ve k+d+i+s tr|E9PQ98|E9PQ98_HUMAN 42 KDKVVLDVGSGTGILCMFAAKAGARKVigIECSSISDYAVKIVKANKLDHVVTiIKGKVEEVELPVE--KVDIIIS 115 45679***************9987765569****************999998866666666655555..9999997 PP >> tr|E9PIX6|E9PIX6_HUMAN Protein arginine N-methyltransferase 1 (Fragment) OS=Homo sapiens GN=PRMT1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.2 0.1 3.5e-07 0.00021 31 103 .. 42 115 .. 32 116 .. 0.80 Alignments for each domain: == domain 1 score: 23.2 bits; conditional E-value: 3.5e-07 TCSEEEEET-TTSHHHHHHHHHTTC.E..EEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTTS-EEEEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakespeae..vtlvdvdarAlesakenleankle.vevvasdvleeveekkfdlivs 103 +++ vlD+G+G+G+l + +ak+ + +++ ++ +A+++ k+n ++ + ++ ++v ve k+d+i+s tr|E9PIX6|E9PIX6_HUMAN 42 KDKVVLDVGSGTGILCMFAAKAGARKVigIECSSISDYAVKIVKANKLDHVVTiIKGKVEEVELPVE--KVDIIIS 115 45679***************9987765569****************999998866666666655555..9999997 PP >> tr|H0YDE4|H0YDE4_HUMAN Protein arginine N-methyltransferase 1 (Fragment) OS=Homo sapiens GN=PRMT1 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.8 0.1 4.7e-07 0.00027 31 103 .. 98 171 .. 88 172 .. 0.80 Alignments for each domain: == domain 1 score: 22.8 bits; conditional E-value: 4.7e-07 TCSEEEEET-TTSHHHHHHHHHTTC.E..EEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTTS-EEEEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakespeae..vtlvdvdarAlesakenleankle.vevvasdvleeveekkfdlivs 103 +++ vlD+G+G+G+l + +ak+ + +++ ++ +A+++ k+n ++ + ++ ++v ve k+d+i+s tr|H0YDE4|H0YDE4_HUMAN 98 KDKVVLDVGSGTGILCMFAAKAGARKVigIECSSISDYAVKIVKANKLDHVVTiIKGKVEEVELPVE--KVDIIIS 171 45679***************9987765569****************999998866666666655555..9999997 PP >> sp|Q8N6R0-4|MET13_HUMAN Isoform 2 of Methyltransferase-like protein 13 OS=Homo sapiens GN=METTL13 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.9 0.0 0.00012 0.072 31 142 .. 48 163 .. 36 189 .. 0.81 2 ? 4.8 0.0 0.15 88 38 91 .. 500 554 .. 488 559 .. 0.90 Alignments for each domain: == domain 1 score: 14.9 bits; conditional E-value: 0.00012 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTT.TSTTS-EEEEEE---S....TTTC CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasdvle.eveekkfdlivsNPPf....hagk 111 ++kvl +GcG+ l+ +l + + +++ +d++ ++ ke ++ + ++++++ d+++ e+++++f++++ + +++ sp|Q8N6R0-4|MET13_HUMAN 48 PREKVLVIGCGNSELSEQLYDVGYR-DIVNIDISEVVIKQMKECNATRRPQMSFLKMDMTQmEFPDASFQVVLDKGTLdavlTDEE 132 4678***************998777.8999****************************99746789******98766511115667 PP HCHHHHHHHHHHHHHHHEEEEEEEEEEEETT CS MTS 112 atelavaeeliaeAkeaLkegGeLliVanrk 142 +++l+ +++++ae ++L+ gG+ l++ + sp|Q8N6R0-4|MET13_HUMAN 133 EKTLQQVDRMLAEVGRVLQVGGRYLCISLAQ 163 78889999***************99986444 PP == domain 2 score: 4.8 bits; conditional E-value: 0.15 ET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTT CS MTS 38 lGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdvle 91 +G G G l + + ++ p+ +++v++d le+a++ + ++ + ++v+ d+l+ sp|Q8N6R0-4|MET13_HUMAN 500 VGLGGGSLPLFVHDHFPKSCIDAVEIDPSMLEVATQWFGFSQSDrMKVHIADGLD 554 799*********************************9999999989999999876 PP >> sp|O95568|MET18_HUMAN Histidine protein methyltransferase 1 homolog OS=Homo sapiens GN=METTL18 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 0.0 8.3e-07 0.00049 25 71 .. 177 226 .. 160 251 .. 0.78 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 8.3e-07 HHCHCC....TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHH CS MTS 25 etlpke....lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesa 71 +++k+ + +kvlDlGcG G+lg+++ k ++ e+++ d + + ++ sp|O95568|MET18_HUMAN 177 AYFTKAkvkfAGKKVLDLGCGSGLLGITAFKGGSK-EIHFQDYNSMVIDEV 226 45555445667789**************9997666.9*******9998754 PP >> tr|E9PKG1|E9PKG1_HUMAN Protein arginine N-methyltransferase 1 OS=Homo sapiens GN=PRMT1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.9 0.1 8.4e-07 0.00049 31 103 .. 42 115 .. 32 116 .. 0.80 Alignments for each domain: == domain 1 score: 21.9 bits; conditional E-value: 8.4e-07 TCSEEEEET-TTSHHHHHHHHHTTC.E..EEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTTS-EEEEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakespeae..vtlvdvdarAlesakenleankle.vevvasdvleeveekkfdlivs 103 +++ vlD+G+G+G+l + +ak+ + +++ ++ +A+++ k+n ++ + ++ ++v ve k+d+i+s tr|E9PKG1|E9PKG1_HUMAN 42 KDKVVLDVGSGTGILCMFAAKAGARKVigIECSSISDYAVKIVKANKLDHVVTiIKGKVEEVELPVE--KVDIIIS 115 45679***************9987765569****************999998866666666655555..9999987 PP >> sp|Q96LA8|ANM6_HUMAN Protein arginine N-methyltransferase 6 OS=Homo sapiens GN=PRMT6 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.7 0.0 9.8e-07 0.00058 31 103 .. 82 154 .. 71 186 .. 0.79 Alignments for each domain: == domain 1 score: 21.7 bits; conditional E-value: 9.8e-07 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHH.HHHHHHHHHTTGC..EEEEE-STTTTSTTS-EEEEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAl.esakenleankle..vevvasdvleeveekkfdlivs 103 + ++vlD+G+G+G+l++ +a++ + +v +v++ A+ + a+e ++ n+le v+v+ v ++++d+ivs sp|Q96LA8|ANM6_HUMAN 82 RGKTVLDVGAGTGILSIFCAQAGAR-RVYAVEA--SAIwQQAREVVRFNGLEdrVHVLPGPVETVELPEQVDAIVS 154 6788*****************9988.5666655..5662678999999*999777777777655555799999997 PP >> sp|Q99873-3|ANM1_HUMAN Isoform 3 of Protein arginine N-methyltransferase 1 OS=Homo sapiens GN=PRMT1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.8 0.1 9.2e-07 0.00054 31 103 .. 60 133 .. 50 134 .. 0.80 Alignments for each domain: == domain 1 score: 21.8 bits; conditional E-value: 9.2e-07 TCSEEEEET-TTSHHHHHHHHHTTC.E..EEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTTS-EEEEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakespeae..vtlvdvdarAlesakenleankle.vevvasdvleeveekkfdlivs 103 +++ vlD+G+G+G+l + +ak+ + +++ ++ +A+++ k+n ++ + ++ ++v ve k+d+i+s sp|Q99873-3|ANM1_HUMAN 60 KDKVVLDVGSGTGILCMFAAKAGARKVigIECSSISDYAVKIVKANKLDHVVTiIKGKVEEVELPVE--KVDIIIS 133 45679***************9987765569****************999998866666666655555..9999987 PP >> sp|Q99873-2|ANM1_HUMAN Isoform 2 of Protein arginine N-methyltransferase 1 OS=Homo sapiens GN=PRMT1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.8 0.1 9.4e-07 0.00055 31 103 .. 64 137 .. 54 138 .. 0.80 Alignments for each domain: == domain 1 score: 21.8 bits; conditional E-value: 9.4e-07 TCSEEEEET-TTSHHHHHHHHHTTC.E..EEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTTS-EEEEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakespeae..vtlvdvdarAlesakenleankle.vevvasdvleeveekkfdlivs 103 +++ vlD+G+G+G+l + +ak+ + +++ ++ +A+++ k+n ++ + ++ ++v ve k+d+i+s sp|Q99873-2|ANM1_HUMAN 64 KDKVVLDVGSGTGILCMFAAKAGARKVigIECSSISDYAVKIVKANKLDHVVTiIKGKVEEVELPVE--KVDIIIS 137 45679***************9987765569****************999998866666666655555..9999987 PP >> tr|B4E2X3|B4E2X3_HUMAN Methyltransferase-like protein 13 OS=Homo sapiens GN=METTL13 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.7 0.0 0.00014 0.083 31 142 .. 47 162 .. 35 187 .. 0.81 2 ? 4.7 0.0 0.17 98 38 91 .. 499 553 .. 487 558 .. 0.90 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 0.00014 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTT.TSTTS-EEEEEE---S....TTTCH CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasdvle.eveekkfdlivsNPPf....hagka 112 ++kvl +GcG+ l+ +l + + +++ +d++ ++ ke ++ + ++++++ d+++ e+++++f++++ + ++++ tr|B4E2X3|B4E2X3_HUMAN 47 PREKVLVIGCGNSELSEQLYDVGYR-DIVNIDISEVVIKQMKECNATRRPQMSFLKMDMTQmEFPDASFQVVLDKGTLdavlTDEEE 132 4678***************998777.8999****************************99746789******987665111156677 PP CHHHHHHHHHHHHHHHEEEEEEEEEEEETT CS MTS 113 telavaeeliaeAkeaLkegGeLliVanrk 142 ++l+ +++++ae ++L+ gG+ l++ + tr|B4E2X3|B4E2X3_HUMAN 133 KTLQQVDRMLAEVGRVLQVGGRYLCISLAQ 162 8889999***************99986444 PP == domain 2 score: 4.7 bits; conditional E-value: 0.17 ET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTT CS MTS 38 lGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdvle 91 +G G G l + + ++ p+ +++v++d le+a++ + ++ + ++v+ d+l+ tr|B4E2X3|B4E2X3_HUMAN 499 VGLGGGSLPLFVHDHFPKSCIDAVEIDPSMLEVATQWFGFSQSDrMKVHIADGLD 553 799*********************************9999999989999999876 PP >> sp|Q99873-4|ANM1_HUMAN Isoform 4 of Protein arginine N-methyltransferase 1 OS=Homo sapiens GN=PRMT1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.7 0.1 9.6e-07 0.00056 31 103 .. 70 143 .. 60 144 .. 0.80 Alignments for each domain: == domain 1 score: 21.7 bits; conditional E-value: 9.6e-07 TCSEEEEET-TTSHHHHHHHHHTTC.E..EEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTTS-EEEEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakespeae..vtlvdvdarAlesakenleankle.vevvasdvleeveekkfdlivs 103 +++ vlD+G+G+G+l + +ak+ + +++ ++ +A+++ k+n ++ + ++ ++v ve k+d+i+s sp|Q99873-4|ANM1_HUMAN 70 KDKVVLDVGSGTGILCMFAAKAGARKVigIECSSISDYAVKIVKANKLDHVVTiIKGKVEEVELPVE--KVDIIIS 143 45679***************9987765569****************999998866666666655555..9999987 PP >> sp|Q8N6R0|MET13_HUMAN Methyltransferase-like protein 13 OS=Homo sapiens GN=METTL13 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 14.7 0.0 0.00014 0.083 31 142 .. 48 163 .. 36 188 .. 0.81 2 ? 4.7 0.0 0.17 99 38 91 .. 500 554 .. 488 559 .. 0.90 Alignments for each domain: == domain 1 score: 14.7 bits; conditional E-value: 0.00014 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTT.TSTTS-EEEEEE---S....TTTCHC CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasdvle.eveekkfdlivsNPPf....hagkat 113 ++kvl +GcG+ l+ +l + + +++ +d++ ++ ke ++ + ++++++ d+++ e+++++f++++ + +++++ sp|Q8N6R0|MET13_HUMAN 48 PREKVLVIGCGNSELSEQLYDVGYR-DIVNIDISEVVIKQMKECNATRRPQMSFLKMDMTQmEFPDASFQVVLDKGTLdavlTDEEEK 134 4678***************998777.8999****************************99746789******9876651111566778 PP HHHHHHHHHHHHHHHEEEEEEEEEEEETT CS MTS 114 elavaeeliaeAkeaLkegGeLliVanrk 142 +l+ +++++ae ++L+ gG+ l++ + sp|Q8N6R0|MET13_HUMAN 135 TLQQVDRMLAEVGRVLQVGGRYLCISLAQ 163 889999***************99986444 PP == domain 2 score: 4.7 bits; conditional E-value: 0.17 ET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTT CS MTS 38 lGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdvle 91 +G G G l + + ++ p+ +++v++d le+a++ + ++ + ++v+ d+l+ sp|Q8N6R0|MET13_HUMAN 500 VGLGGGSLPLFVHDHFPKSCIDAVEIDPSMLEVATQWFGFSQSDrMKVHIADGLD 554 799*********************************9999999989999999876 PP >> tr|H3BQF6|H3BQF6_HUMAN Uncharacterized protein (Fragment) OS=Homo sapiens PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.6 0.0 1.1e-06 0.00062 23 91 .. 33 104 .. 29 155 .. 0.85 Alignments for each domain: == domain 1 score: 21.6 bits; conditional E-value: 1.1e-06 HHHHCHCC...TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTT CS MTS 23 Lletlpke...lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdvle 91 L++ ++k+ l+ +vlD+G+G+Gv ++lak+ + ++t +d + A++++ +e+++l+ +++ +d l+ tr|H3BQF6|H3BQF6_HUMAN 33 LIRWMQKHkipLDASVLDIGTGNGVFLVELAKFGFS-NITGIDYSPSAIQLSGSIIEKEGLSnIKLKVEDFLN 104 566677766777889*****************9888.7*****************999999988888888765 PP >> sp|Q99873|ANM1_HUMAN Protein arginine N-methyltransferase 1 OS=Homo sapiens GN=PRMT1 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.7 0.1 1e-06 0.00059 31 103 .. 78 151 .. 68 152 .. 0.80 Alignments for each domain: == domain 1 score: 21.7 bits; conditional E-value: 1e-06 TCSEEEEET-TTSHHHHHHHHHTTC.E..EEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTTS-EEEEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakespeae..vtlvdvdarAlesakenleankle.vevvasdvleeveekkfdlivs 103 +++ vlD+G+G+G+l + +ak+ + +++ ++ +A+++ k+n ++ + ++ ++v ve k+d+i+s sp|Q99873|ANM1_HUMAN 78 KDKVVLDVGSGTGILCMFAAKAGARKVigIECSSISDYAVKIVKANKLDHVVTiIKGKVEEVELPVE--KVDIIIS 151 45679***************9987765569****************999998866666666655555..9999987 PP >> tr|H7C2I1|H7C2I1_HUMAN Protein arginine N-methyltransferase 1 OS=Homo sapiens GN=PRMT1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.6 0.1 1e-06 0.00061 31 103 .. 88 161 .. 78 162 .. 0.80 Alignments for each domain: == domain 1 score: 21.6 bits; conditional E-value: 1e-06 TCSEEEEET-TTSHHHHHHHHHTTC.E..EEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTTS-EEEEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakespeae..vtlvdvdarAlesakenleankle.vevvasdvleeveekkfdlivs 103 +++ vlD+G+G+G+l + +ak+ + +++ ++ +A+++ k+n ++ + ++ ++v ve k+d+i+s tr|H7C2I1|H7C2I1_HUMAN 88 KDKVVLDVGSGTGILCMFAAKAGARKVigIECSSISDYAVKIVKANKLDHVVTiIKGKVEEVELPVE--KVDIIIS 161 45679***************9987765569****************999998866666666655555..9999987 PP >> tr|H7C0M7|H7C0M7_HUMAN Methyltransferase-like protein 5 (Fragment) OS=Homo sapiens GN=METTL5 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 21.7 0.0 1e-06 0.00059 74 126 .. 4 57 .. 1 90 [. 0.70 Alignments for each domain: == domain 1 score: 21.7 bits; conditional E-value: 1e-06 HHHHTTGC.EEEEE-ST..TTTSTTS-EEEEEE---STTTCHCHHHHHHHHHHHHH CS MTS 74 nleankle.vevvasdv..leeveekkfdlivsNPPfhagkatelavaeeliaeAk 126 n+e+ +l +++v++dv l++ k+fd++++NPPf +++++ + ++++++A tr|H7C0M7|H7C0M7_HUMAN 4 NAEEFELTnIDMVQCDVclLSNRMSKSFDTVIMNPPFGTKNNK--GTDMAFLKTAL 57 5555555568888888633688889************877653..33334444443 PP >> sp|Q8IXQ9|MET20_HUMAN Methyltransferase-like protein 20 OS=Homo sapiens GN=METTL20 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.9 0.0 1.8e-06 0.001 20 102 .. 104 185 .. 98 194 .. 0.86 Alignments for each domain: == domain 1 score: 20.9 bits; conditional E-value: 1.8e-06 HHHHHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTTS-EEEEE CS MTS 20 sklLletlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdvleeveekkfdliv 102 s+ Ll++ + + ++vlDlG+G G+ ++a ak+s ++ + d+d A + + n+e n+l+ ++ +++l+ + +k dl+v sp|Q8IXQ9|MET20_HUMAN 104 SRYLLDNPDVVRGKSVLDLGSGCGATAIA-AKMSGASRILANDIDPIAGMAITLNCELNRLNpFPILIQNILNLEQ-DKWDLVV 185 566777777779999*********98775.66677779************************999999*9998666.9999998 PP >> sp|Q5JPI9|MET10_HUMAN Methyltransferase-like protein 10 OS=Homo sapiens GN=METTL10 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 20.5 0.0 2.4e-06 0.0014 23 91 .. 68 139 .. 64 192 .. 0.85 Alignments for each domain: == domain 1 score: 20.5 bits; conditional E-value: 2.4e-06 HHHHCHCC...TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTT CS MTS 23 Lletlpke...lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdvle 91 L++ ++k+ l+ +vlD+G+G+Gv ++lak+ + ++t +d + A++++ +e+++l+ +++ +d l+ sp|Q5JPI9|MET10_HUMAN 68 LIRWMQKHkipLDASVLDIGTGNGVFLVELAKFGFS-NITGIDYSPSAIQLSGSIIEKEGLSnIKLKVEDFLN 139 566666666777889*****************9888.7****************9999999988888888765 PP >> sp|Q7L2J0|MEPCE_HUMAN 7SK snRNA methylphosphate capping enzyme OS=Homo sapiens GN=MEPCE PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.9 0.0 7.1e-06 0.0042 30 77 .. 440 489 .. 434 501 .. 0.88 Alignments for each domain: == domain 1 score: 18.9 bits; conditional E-value: 7.1e-06 C..TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHH CS MTS 30 e..lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenlea 77 e + ++vlDlGc +G l++++a ++ +++ +d+d r ++sa++n+++ sp|Q7L2J0|MEPCE_HUMAN 440 EwfRGRDVLDLGCNVGHLTLSIACKWGPSRMVGLDIDSRLIHSARQNIRH 489 4556788****************************************975 PP >> sp|Q8TCB7-2|METL6_HUMAN Isoform 2 of Methyltransferase-like protein 6 OS=Homo sapiens GN=METTL6 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.8 0.0 3.8e-06 0.0022 33 102 .. 81 155 .. 73 156 .. 0.81 Alignments for each domain: == domain 1 score: 19.8 bits; conditional E-value: 3.8e-06 SEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.....EEEEE-STTTTSTTS-EEEEE CS MTS 33 gkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.....vevvasdvleeveekkfdliv 102 ++l GcG+G l++e p++ ++d + rA+e k+n + +++++ d+l++v+++++d+++ sp|Q8TCB7-2|METL6_HUMAN 81 LTMLEAGCGVGNCLFPLLEEDPNIFAYACDFSPRAIEYVKQNPLYDTERckvfqCDLTKDDLLDHVPPESVDVVM 155 458899***********************************9765555522555667777788889999999886 PP >> sp|Q8TCB7|METL6_HUMAN Methyltransferase-like protein 6 OS=Homo sapiens GN=METTL6 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.4 0.0 4.9e-06 0.0029 33 102 .. 81 155 .. 73 157 .. 0.81 Alignments for each domain: == domain 1 score: 19.4 bits; conditional E-value: 4.9e-06 SEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.....EEEEE-STTTTSTTS-EEEEE CS MTS 33 gkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.....vevvasdvleeveekkfdliv 102 ++l GcG+G l++e p++ ++d + rA+e k+n + +++++ d+l++v+++++d+++ sp|Q8TCB7|METL6_HUMAN 81 LTMLEAGCGVGNCLFPLLEEDPNIFAYACDFSPRAIEYVKQNPLYDTERckvfqCDLTKDDLLDHVPPESVDVVM 155 457899***********************************9765555522555677777888889999999986 PP >> sp|Q8NEC7-3|GSTCD_HUMAN Isoform 2 of Glutathione S-transferase C-terminal domain-containing protein OS=Homo sapiens # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.9 0.0 7.3e-06 0.0043 30 82 .. 353 406 .. 342 419 .. 0.82 Alignments for each domain: == domain 1 score: 18.9 bits; conditional E-value: 7.3e-06 CTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.E CS MTS 30 elsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.v 82 + ++++D+++G G +g++la++ p+ +vtl++++ +l ak+ + +l+ + sp|Q8NEC7-3|GSTCD_HUMAN 353 KPGDRIVDFCSGGGHVGIVLAHMLPSCQVTLIENKELSLIRAKKRSDELGLSnI 406 36789*******************************999999988777666644 PP >> tr|B3KU92|B3KU92_HUMAN Putative protein arginine N-methyltransferase 10 OS=Homo sapiens GN=LOC90826 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.4 0.1 1e-05 0.0059 32 86 .. 65 120 .. 55 141 .. 0.84 Alignments for each domain: == domain 1 score: 18.4 bits; conditional E-value: 1e-05 CSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE CS MTS 32 sgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevva 86 s++vlD+G+G+G+l++ ++k+ + +v +++ ++ e+a ++ank+e +++++ tr|B3KU92|B3KU92_HUMAN 65 SKSVLDIGAGTGILSMFAKKAGAH-SVYACELSKTMYELACDVVAANKMEagIKLLH 120 578************998887777.8**********************996655544 PP >> sp|Q8NEC7|GSTCD_HUMAN Glutathione S-transferase C-terminal domain-containing protein OS=Homo sapiens GN=GSTCD PE=1 S # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.6 0.0 8.9e-06 0.0052 30 82 .. 440 493 .. 429 506 .. 0.82 Alignments for each domain: == domain 1 score: 18.6 bits; conditional E-value: 8.9e-06 CTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.E CS MTS 30 elsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.v 82 + ++++D+++G G +g++la++ p+ +vtl++++ +l ak+ + +l+ + sp|Q8NEC7|GSTCD_HUMAN 440 KPGDRIVDFCSGGGHVGIVLAHMLPSCQVTLIENKELSLIRAKKRSDELGLSnI 493 36789*******************************999999988777666644 PP >> sp|Q6P2P2|ANM10_HUMAN Putative protein arginine N-methyltransferase 10 OS=Homo sapiens GN=PRMT10 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.2 0.1 1.2e-05 0.0071 32 86 .. 178 233 .. 168 254 .. 0.84 Alignments for each domain: == domain 1 score: 18.2 bits; conditional E-value: 1.2e-05 CSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE CS MTS 32 sgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevva 86 s++vlD+G+G+G+l++ ++k+ + +v +++ ++ e+a ++ank+e +++++ sp|Q6P2P2|ANM10_HUMAN 178 SKSVLDIGAGTGILSMFAKKAGAH-SVYACELSKTMYELACDVVAANKMEagIKLLH 233 578************998887777.8**********************996655544 PP >> sp|Q8WXB1|MT21A_HUMAN Protein N-lysine methyltransferase METTL21A OS=Homo sapiens GN=METTL21A PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.7 0.0 8.5e-06 0.005 31 85 .. 65 124 .. 46 142 .. 0.71 Alignments for each domain: == domain 1 score: 18.7 bits; conditional E-value: 8.5e-06 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC........EEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle........vevv 85 + ++++ lG+G+G++g+++a + vt++d + Ale+ k n++an e++ sp|Q8WXB1|MT21A_HUMAN 65 RGRSAVELGAGTGLVGIVAALLGAH--VTITDRK-VALEFLKSNVQANLPPhiqtktvvKELT 124 56789***************99888..8888875.69**********9876544333333444 PP >> tr|E9PMW9|E9PMW9_HUMAN Protein arginine N-methyltransferase 1 (Fragment) OS=Homo sapiens GN=PRMT1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.7 0.0 8.4e-06 0.0049 31 74 .. 64 109 .. 48 110 .] 0.84 Alignments for each domain: == domain 1 score: 18.7 bits; conditional E-value: 8.4e-06 TCSEEEEET-TTSHHHHHHHHHTTC.E..EEEEESBHHHHHHHHHH CS MTS 31 lsgkvlDlGcGaGvlgaalakespeae..vtlvdvdarAlesaken 74 +++ vlD+G+G+G+l + +ak+ + +++ ++ +A+++ k+n tr|E9PMW9|E9PMW9_HUMAN 64 KDKVVLDVGSGTGILCMFAAKAGARKVigIECSSISDYAVKIVKAN 109 46679***************99877555699**********99987 PP >> tr|E9PI83|E9PI83_HUMAN Protein arginine N-methyltransferase 1 (Fragment) OS=Homo sapiens GN=PRMT1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.5 0.0 9.8e-06 0.0057 31 74 .. 67 112 .. 56 113 .] 0.83 Alignments for each domain: == domain 1 score: 18.5 bits; conditional E-value: 9.8e-06 TCSEEEEET-TTSHHHHHHHHHTTC.E..EEEEESBHHHHHHHHHH CS MTS 31 lsgkvlDlGcGaGvlgaalakespeae..vtlvdvdarAlesaken 74 +++ vlD+G+G+G+l + +ak+ + +++ ++ +A+++ k+n tr|E9PI83|E9PI83_HUMAN 67 KDKVVLDVGSGTGILCMFAAKAGARKVigIECSSISDYAVKIVKAN 112 46679***************99877555699**********99987 PP >> tr|H7C2C8|H7C2C8_HUMAN Methyltransferase-like protein 2B (Fragment) OS=Homo sapiens GN=METTL2B PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.8 0.0 7.8e-06 0.0046 33 109 .. 5 83 .. 1 99 [. 0.80 Alignments for each domain: == domain 1 score: 18.8 bits; conditional E-value: 7.8e-06 SEEEEET-TTSHHHHHHHHHT..TC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTTSTTS-EEEEEE---STT CS MTS 33 gkvlDlGcGaGvlgaalakes..peaevtlvdvdarAlesakenleanklevevvasdvleeveekkfdlivsNPPfha 109 ++l +GcG+G +++ + p + v ++d + A+e+ + +l++ ++v+ v + + k vs PP+ + tr|H7C2C8|H7C2C8_HUMAN 5 YRILEVGCGVGNTVFPILQTNndPGLFVYCCDFSSTAIELVQFTLSHCTDVISVHILKVCGNPASSKPTSAVSPPPYAH 83 579********8777777665115566******************9998889999999999999899999999999755 PP >> sp|Q9NR22-2|ANM8_HUMAN Isoform 2 of Protein arginine N-methyltransferase 8 OS=Homo sapiens GN=PRMT8 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.5 0.0 1.9e-05 0.011 31 103 .. 102 175 .. 93 176 .. 0.66 Alignments for each domain: == domain 1 score: 17.5 bits; conditional E-value: 1.9e-05 TCSEEEEET-TTSHHHHHHHHHTTC.E..EEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTT.TSTTS-EEEEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakespeae..vtlvdvdarAlesakenleankle..vevvasdvle.eveekkfdlivs 103 +++ vlD+G+G+G+l++ +ak+ + +++ ++ +++ ++an+l+ +++++ v e e++ +k+d+i+s sp|Q9NR22-2|ANM8_HUMAN 102 KDKVVLDVGSGTGILSMFAAKAGAKKVfgIECSSISD----YSEKIIKANHLDniITIFKGKVEEvELPVEKVDIIIS 175 45679****************9988432344444444....5555666666666556666555442444679999987 PP >> sp|Q9NR22|ANM8_HUMAN Protein arginine N-methyltransferase 8 OS=Homo sapiens GN=PRMT8 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.4 0.0 2e-05 0.012 31 103 .. 111 184 .. 102 185 .. 0.66 Alignments for each domain: == domain 1 score: 17.4 bits; conditional E-value: 2e-05 TCSEEEEET-TTSHHHHHHHHHTTC.E..EEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTT.TSTTS-EEEEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakespeae..vtlvdvdarAlesakenleankle..vevvasdvle.eveekkfdlivs 103 +++ vlD+G+G+G+l++ +ak+ + +++ ++ +++ ++an+l+ +++++ v e e++ +k+d+i+s sp|Q9NR22|ANM8_HUMAN 111 KDKVVLDVGSGTGILSMFAAKAGAKKVfgIECSSISD----YSEKIIKANHLDniITIFKGKVEEvELPVEKVDIIIS 184 45679****************9988432344444444....5555666666666556666555442444679999987 PP >> sp|Q96IZ6-2|MET2A_HUMAN Isoform 2 of Methyltransferase-like protein 2A OS=Homo sapiens GN=METTL2A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.6 0.0 1.8e-05 0.011 31 133 .. 44 150 .. 33 160 .. 0.69 Alignments for each domain: == domain 1 score: 17.6 bits; conditional E-value: 1.8e-05 TCSEEEEET-TTSHHHHHHHHHT..TC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTT.....STTS-EEEEEE---STT CS MTS 31 lsgkvlDlGcGaGvlgaalakes..peaevtlvdvdarAlesakenleanklevevvasdvlee.....veekkfdlivsNPPfha 109 ++ ++l +GcG+G +++ + p + v ++d + A+e+ ++n e ++ ++ +d+ +e v+++++d+i+ + sp|Q96IZ6-2|MET2A_HUMAN 44 ATYRILEVGCGVGNTVFPILQTNndPGLFVYCCDFSSTAIELVQTNSEYDPSRCFAFVHDLCDEeksypVPKGSLDIIIL---IFV 126 55689********8777777665115566*******************99999777777776652222245677787776...444 PP TCHCHHHHHHHHHHHHHHHEEEEE CS MTS 110 gkatelavaeeliaeAkeaLkegG 133 +a+ + +++ i+ + Lk+gG sp|Q96IZ6-2|MET2A_HUMAN 127 LSAIVPDKMQKAINRLSRLLKPGG 150 445555555555555555555555 PP >> sp|O14717-3|TRDMT_HUMAN Isoform C of tRNA (cytosine(38)-C(5))-methyltransferase OS=Homo sapiens GN=TRDMT1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.4 0.0 2.1e-05 0.012 34 107 .. 5 79 .. 2 90 .. 0.90 Alignments for each domain: == domain 1 score: 17.4 bits; conditional E-value: 2.1e-05 EEEEET-TTSHHHHHHHHHTTC.E.EEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTTSTTS-EEEEEE---S CS MTS 34 kvlDlGcGaGvlgaalakespeae.vtlvdvdarAlesakenleanklevevvasdvleeveekkfdlivsNPPf 107 +vl l +G+G + al + + a+ v ++dv++ A e+ k n+ +++l +++++ lee++ +fd+i++ PP sp|O14717-3|TRDMT_HUMAN 5 RVLELYSGVGGMHHALRESCIPAQvVAAIDVNTVANEVYKYNFPHTQLLAKTIEGITLEEFDRLSFDMILMSPPC 79 5889999999999999888755554999*********************************************96 PP >> sp|O14717-2|TRDMT_HUMAN Isoform B of tRNA (cytosine(38)-C(5))-methyltransferase OS=Homo sapiens GN=TRDMT1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.3 0.0 2.2e-05 0.013 34 107 .. 5 79 .. 2 92 .. 0.90 Alignments for each domain: == domain 1 score: 17.3 bits; conditional E-value: 2.2e-05 EEEEET-TTSHHHHHHHHHTTC.E.EEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTTSTTS-EEEEEE---S CS MTS 34 kvlDlGcGaGvlgaalakespeae.vtlvdvdarAlesakenleanklevevvasdvleeveekkfdlivsNPPf 107 +vl l +G+G + al + + a+ v ++dv++ A e+ k n+ +++l +++++ lee++ +fd+i++ PP sp|O14717-2|TRDMT_HUMAN 5 RVLELYSGVGGMHHALRESCIPAQvVAAIDVNTVANEVYKYNFPHTQLLAKTIEGITLEEFDRLSFDMILMSPPC 79 5889999999999999888755554999*********************************************96 PP >> sp|O14717|TRDMT_HUMAN tRNA (cytosine(38)-C(5))-methyltransferase OS=Homo sapiens GN=TRDMT1 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.1 0.0 2.6e-05 0.015 34 107 .. 5 79 .. 2 89 .. 0.91 Alignments for each domain: == domain 1 score: 17.1 bits; conditional E-value: 2.6e-05 EEEEET-TTSHHHHHHHHHTTC.E.EEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTTSTTS-EEEEEE---S CS MTS 34 kvlDlGcGaGvlgaalakespeae.vtlvdvdarAlesakenleanklevevvasdvleeveekkfdlivsNPPf 107 +vl l +G+G + al + + a+ v ++dv++ A e+ k n+ +++l +++++ lee++ +fd+i++ PP sp|O14717|TRDMT_HUMAN 5 RVLELYSGVGGMHHALRESCIPAQvVAAIDVNTVANEVYKYNFPHTQLLAKTIEGITLEEFDRLSFDMILMSPPC 79 5889999999999999888755554999**********************************************6 PP >> sp|Q96AZ1|MT21B_HUMAN Protein-lysine methyltransferase METTL21B OS=Homo sapiens GN=METTL21B PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.3 0.0 2.3e-05 0.014 25 101 .. 65 147 .. 52 149 .. 0.73 Alignments for each domain: == domain 1 score: 17.3 bits; conditional E-value: 2.3e-05 HHCHCC....TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.....EEEEE-STTTTSTTS-EEEE CS MTS 25 etlpke....lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.....vevvasdvleeveekkfdli 101 ++++++ + +kv+ lG+G+G++g+ +a + + vt++d Ale + n++an + v+++ + ++v ++++dl+ sp|Q96AZ1|MT21B_HUMAN 65 NYFESQnvdfRGKKVIELGAGTGIVGILAALQGGD--VTITDLP-LALEQIQGNVQANVPAggqaqVRALSWGIDHHVFPANYDLV 147 55555555667889**************9999888..8888875.69**********98876553344444445555556666665 PP >> sp|Q96IZ6|MET2A_HUMAN Methyltransferase-like protein 2A OS=Homo sapiens GN=METTL2A PE=1 SV=5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 0.0 4.8e-05 0.028 31 103 .. 180 259 .. 169 293 .. 0.69 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 4.8e-05 TCSEEEEET-TTSHHHHHHHHHT..TC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTT.....STTS-EEEEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakes..peaevtlvdvdarAlesakenleanklevevvasdvlee.....veekkfdlivs 103 ++ ++l +GcG+G +++ + p + v ++d + A+e+ ++n e ++ ++ +d+ +e v+++++d+i+ sp|Q96IZ6|MET2A_HUMAN 180 ATYRILEVGCGVGNTVFPILQTNndPGLFVYCCDFSSTAIELVQTNSEYDPSRCFAFVHDLCDEeksypVPKGSLDIIIL 259 55689********8777777665115566*******************99999777777776652222244677777775 PP >> tr|H0YFV5|H0YFV5_HUMAN Methyltransferase-like protein 5 (Fragment) OS=Homo sapiens GN=METTL5 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 17.3 0.2 2.2e-05 0.013 27 50 .. 30 57 .. 22 65 .. 0.74 Alignments for each domain: == domain 1 score: 17.3 bits; conditional E-value: 2.2e-05 CHCC....TCSEEEEET-TTSHHHHHHH CS MTS 27 lpke....lsgkvlDlGcGaGvlgaala 50 ++++ +++ v+DlGcG Gvl++ a tr|H0YFV5|H0YFV5_HUMAN 30 IHNTyddiENKVVADLGCGCGVLSIGTA 57 5444445467779***********9766 PP >> sp|Q6P1Q9|MET2B_HUMAN Methyltransferase-like protein 2B OS=Homo sapiens GN=METTL2B PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.9 0.0 6.1e-05 0.036 31 102 .. 180 258 .. 169 291 .. 0.71 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 6.1e-05 TCSEEEEET-TTSHHHHHHHHHT..TC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTT.....STTS-EEEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakes..peaevtlvdvdarAlesakenleanklevevvasdvlee.....veekkfdliv 102 ++ ++l +GcG+G +++ + p + v ++d + A+e+ ++n e ++ ++ +d+ +e v+++++d+i+ sp|Q6P1Q9|MET2B_HUMAN 180 ATYRILEVGCGVGNTVFPILQTNndPGLFVYCCDFSSTAIELVQTNSEYDPSRCFAFVHDLCDEeksypVPKGSLDIII 258 55689********8777777665115566*******************9999977777777665122224456667766 PP >> sp|Q8N6R0-1|MET13_HUMAN Isoform 4 of Methyltransferase-like protein 13 OS=Homo sapiens GN=METTL13 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.1 0.0 0.0073 4.3 31 102 .. 48 119 .. 36 152 .. 0.84 2 ? 5.2 0.0 0.12 69 38 92 .. 344 399 .. 331 403 .. 0.89 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 0.0073 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTT.TSTTS-EEEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasdvle.eveekkfdliv 102 ++kvl +GcG+ l+ +l + + +++ +d++ ++ ke ++ + ++++++ d+++ e+++++f++++ sp|Q8N6R0-1|MET13_HUMAN 48 PREKVLVIGCGNSELSEQLYDVGYR-DIVNIDISEVVIKQMKECNATRRPQMSFLKMDMTQmEFPDASFQVVL 119 4678***************998777.8999****************************987356788888886 PP == domain 2 score: 5.2 bits; conditional E-value: 0.12 ET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTT CS MTS 38 lGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdvlee 92 +G G G l + + ++ p+ +++v++d le+a++ + ++ + ++v+ d+l+ sp|Q8N6R0-1|MET13_HUMAN 344 VGLGGGSLPLFVHDHFPKSCIDAVEIDPSMLEVATQWFGFSQSDrMKVHIADGLDY 399 799*********************************99999999899999998875 PP >> sp|A8MUP2|MET12_HUMAN Methyltransferase-like protein 12, mitochondrial OS=Homo sapiens GN=METTL12 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.7 0.0 6.9e-05 0.04 19 74 .. 60 117 .. 55 127 .. 0.76 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 6.9e-05 HHHHHHHHCHCC...TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHH CS MTS 19 GsklLletlpke...lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesaken 74 lLl l+++ +vlD+GcG+ l + l +sp+ v+++ vd+ +++a+ n sp|A8MUP2|MET12_HUMAN 60 VQGLLLPLLQEAqaaSPLRVLDVGCGTSSLCTGLYTKSPH-PVDVLGVDFSPVAVAHMN 117 5568888888885444446********************9.577777777777777666 PP >> sp|Q6P1Q9-2|MET2B_HUMAN Isoform 2 of Methyltransferase-like protein 2B OS=Homo sapiens GN=METTL2B # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.4 0.0 4.3e-05 0.025 31 102 .. 115 193 .. 104 226 .. 0.71 Alignments for each domain: == domain 1 score: 16.4 bits; conditional E-value: 4.3e-05 TCSEEEEET-TTSHHHHHHHHHT..TC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTT.....STTS-EEEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakes..peaevtlvdvdarAlesakenleanklevevvasdvlee.....veekkfdliv 102 ++ ++l +GcG+G +++ + p + v ++d + A+e+ ++n e ++ ++ +d+ +e v+++++d+i+ sp|Q6P1Q9-2|MET2B_HUMAN 115 ATYRILEVGCGVGNTVFPILQTNndPGLFVYCCDFSSTAIELVQTNSEYDPSRCFAFVHDLCDEeksypVPKGSLDIII 193 55689********8777777665115566*******************9999977777777665122224466677776 PP >> tr|B3KR61|B3KR61_HUMAN HCG1811060, isoform CRA_c OS=Homo sapiens GN=NDUFAF5 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 16.5 0.0 4e-05 0.023 35 103 .. 93 157 .. 69 174 .. 0.84 Alignments for each domain: == domain 1 score: 16.5 bits; conditional E-value: 4e-05 EEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTTSTTS-EEEEEE CS MTS 35 vlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasdvleeveekkfdlivs 103 +lDlGcG G+++ l ke+ + d+ +Al+ + e+ + v+v+a + + ++e+ fdl+vs tr|B3KR61|B3KR61_HUMAN 93 ALDLGCGRGYIAQYLNKETIG-KFFQADIAENALKNSSET---EIPTVSVLADEEFLPFKENTFDLVVS 157 79*************998887.788899999999877665...33347888888888888888888886 PP >> tr|A8MTP3|A8MTP3_HUMAN Protein arginine N-methyltransferase 5 OS=Homo sapiens GN=PRMT5 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.9 0.0 6.1e-05 0.036 23 103 .. 174 263 .. 171 292 .. 0.69 Alignments for each domain: == domain 1 score: 15.9 bits; conditional E-value: 6.1e-05 HHHHCHCC...TCSE.EEEET-TTSHH...HHHHHHHTT.C.EEEEEESBHHHHHHHHH.HHHHTTGCEEEEE-STTTTSTTS-EEE CS MTS 23 Lletlpke...lsgk.vlDlGcGaGvl...gaalakesp.eaevtlvdvdarAlesake.nleanklevevvasdvleeveekkfdl 100 Ll+ +p+e ++ + ++ lG+G G+l ++ +ak+ + ++++ +v+++ +A+ ++ +e+ + +v+vv sd+ e v+++k d+ tr|A8MTP3|A8MTP3_HUMAN 174 LLDRVPEEekdTNVQvLMVLGAGRGPLvnaSLRAAKQADrRIKLYAVEKNPNAVVTLENwQFEEWGSQVTVVSSDMREWVAPEKADI 260 66666665433222225569*****994433444444331456999*******865543156666677******************* PP EEE CS MTS 101 ivs 103 ivs tr|A8MTP3|A8MTP3_HUMAN 261 IVS 263 **8 PP >> sp|Q5TEU4|NDUF5_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 OS=Homo sapiens GN=NDUFAF # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.8 0.0 6.6e-05 0.039 35 103 .. 93 157 .. 74 173 .. 0.83 Alignments for each domain: == domain 1 score: 15.8 bits; conditional E-value: 6.6e-05 EEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTTSTTS-EEEEEE CS MTS 35 vlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasdvleeveekkfdlivs 103 +lDlGcG G+++ l ke+ + d+ +Al+ + e+ + v+v+a + + ++e+ fdl+vs sp|Q5TEU4|NDUF5_HUMAN 93 ALDLGCGRGYIAQYLNKETIG-KFFQADIAENALKNSSET---EIPTVSVLADEEFLPFKENTFDLVVS 157 79*************998887.788899999999877665...23337888888888888888888886 PP >> tr|B4DV00|B4DV00_HUMAN Protein arginine N-methyltransferase 5 OS=Homo sapiens GN=PRMT5 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.6 0.0 7.6e-05 0.045 23 103 .. 239 328 .. 236 357 .. 0.69 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 7.6e-05 HHHHCHCC...TCSE.EEEET-TTSHH...HHHHHHHTT.C.EEEEEESBHHHHHHHHH.HHHHTTGCEEEEE-STTTTSTTS-EEE CS MTS 23 Lletlpke...lsgk.vlDlGcGaGvl...gaalakesp.eaevtlvdvdarAlesake.nleanklevevvasdvleeveekkfdl 100 Ll+ +p+e ++ + ++ lG+G G+l ++ +ak+ + ++++ +v+++ +A+ ++ +e+ + +v+vv sd+ e v+++k d+ tr|B4DV00|B4DV00_HUMAN 239 LLDRVPEEekdTNVQvLMVLGAGRGPLvnaSLRAAKQADrRIKLYAVEKNPNAVVTLENwQFEEWGSQVTVVSSDMREWVAPEKADI 325 66666665433222225569*****994433444444331456999*******865543156666677******************* PP EEE CS MTS 101 ivs 103 ivs tr|B4DV00|B4DV00_HUMAN 326 IVS 328 **8 PP >> sp|Q53H54|TYW2_HUMAN tRNA wybutosine-synthesizing protein 2 homolog OS=Homo sapiens GN=TRMT12 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.6 0.0 7.4e-05 0.043 31 89 .. 234 294 .. 208 308 .. 0.83 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 7.4e-05 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-ST CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdv 89 + + ++Dl +G+G+ ++ ++ + a v++++ + +A+ + ++nle n+++ ++++ d sp|Q53H54|TYW2_HUMAN 234 AGEVLVDLYAGIGYFTLPFLVHAGAAFVHACEWNPHAVVALRNNLEINGVAdrCQIHFGDN 294 445679*******************************************998888877765 PP >> sp|Q96S19|CP013_HUMAN UPF0585 protein C16orf13 OS=Homo sapiens GN=C16orf13 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.7 0.0 6.8e-05 0.04 21 82 .. 16 79 .. 7 137 .. 0.85 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 6.8e-05 HHHHHHCHCC.TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.E CS MTS 21 klLletlpke.lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.v 82 ++L ++l+ + + +vl +++G G +a++a++ p ae + dvd r l+s ++ +a++l v sp|Q96S19|CP013_HUMAN 16 HVLRQYLDPAqRGVRVLEVASGSGQHAAHFARAFPLAEWQPSDVDQRCLDSIAATTQAQGLTnV 79 567788887756678******************************************9998753 PP >> tr|H3BNB2|H3BNB2_HUMAN UPF0585 protein C16orf13 (Fragment) OS=Homo sapiens GN=C16orf13 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.6 0.0 7.3e-05 0.043 21 82 .. 16 79 .. 7 94 .. 0.85 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 7.3e-05 HHHHHHCHCC.TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.E CS MTS 21 klLletlpke.lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.v 82 ++L ++l+ + + +vl +++G G +a++a++ p ae + dvd r l+s ++ +a++l v tr|H3BNB2|H3BNB2_HUMAN 16 HVLRQYLDPAqRGVRVLEVASGSGQHAAHFARAFPLAEWQPSDVDQRCLDSIAATTQAQGLTnV 79 567788887756678******************************************9998753 PP >> tr|B4DX49|B4DX49_HUMAN Protein arginine N-methyltransferase 5 OS=Homo sapiens GN=PRMT5 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.4 0.0 8.7e-05 0.051 23 103 .. 284 373 .. 281 402 .. 0.69 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 8.7e-05 HHHHCHCC...TCSE.EEEET-TTSHH...HHHHHHHTT.C.EEEEEESBHHHHHHHHH.HHHHTTGCEEEEE-STTTTSTTS-EEE CS MTS 23 Lletlpke...lsgk.vlDlGcGaGvl...gaalakesp.eaevtlvdvdarAlesake.nleanklevevvasdvleeveekkfdl 100 Ll+ +p+e ++ + ++ lG+G G+l ++ +ak+ + ++++ +v+++ +A+ ++ +e+ + +v+vv sd+ e v+++k d+ tr|B4DX49|B4DX49_HUMAN 284 LLDRVPEEekdTNVQvLMVLGAGRGPLvnaSLRAAKQADrRIKLYAVEKNPNAVVTLENwQFEEWGSQVTVVSSDMREWVAPEKADI 370 56666665433222225569*****994433444444331456999*******865543156666677******************* PP EEE CS MTS 101 ivs 103 ivs tr|B4DX49|B4DX49_HUMAN 371 IVS 373 **8 PP >> tr|G3V5W5|G3V5W5_HUMAN Protein arginine N-methyltransferase 5 OS=Homo sapiens GN=PRMT5 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.3 0.0 9.1e-05 0.053 23 103 .. 301 390 .. 298 419 .. 0.69 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 9.1e-05 HHHHCHCC...TCSE.EEEET-TTSHH...HHHHHHHTT.C.EEEEEESBHHHHHHHHH.HHHHTTGCEEEEE-STTTTSTTS-EEE CS MTS 23 Lletlpke...lsgk.vlDlGcGaGvl...gaalakesp.eaevtlvdvdarAlesake.nleanklevevvasdvleeveekkfdl 100 Ll+ +p+e ++ + ++ lG+G G+l ++ +ak+ + ++++ +v+++ +A+ ++ +e+ + +v+vv sd+ e v+++k d+ tr|G3V5W5|G3V5W5_HUMAN 301 LLDRVPEEekdTNVQvLMVLGAGRGPLvnaSLRAAKQADrRIKLYAVEKNPNAVVTLENwQFEEWGSQVTVVSSDMREWVAPEKADI 387 56666665433222225569*****994433444444331456999*******865543156666677******************* PP EEE CS MTS 101 ivs 103 ivs tr|G3V5W5|G3V5W5_HUMAN 388 IVS 390 **8 PP >> sp|Q14749|GNMT_HUMAN Glycine N-methyltransferase OS=Homo sapiens GN=GNMT PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.6 0.0 7.5e-05 0.044 23 74 .. 49 98 .. 46 183 .. 0.78 Alignments for each domain: == domain 1 score: 15.6 bits; conditional E-value: 7.5e-05 HHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHH CS MTS 23 LletlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesaken 74 Ll l ++ ++vlD++cG+Gv +++l +e + vt vd++ + l+ a + sp|Q14749|GNMT_HUMAN 49 LLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFS--VTSVDASDKMLKYALKE 98 777788887789***************997766..88888887777766544 PP >> sp|Q96S19-4|CP013_HUMAN Isoform 4 of UPF0585 protein C16orf13 OS=Homo sapiens GN=C16orf13 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.8 0.0 6.5e-05 0.038 21 82 .. 16 79 .. 7 142 .. 0.84 Alignments for each domain: == domain 1 score: 15.8 bits; conditional E-value: 6.5e-05 HHHHHHCHCC.TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.E CS MTS 21 klLletlpke.lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.v 82 ++L ++l+ + + +vl +++G G +a++a++ p ae + dvd r l+s ++ +a++l v sp|Q96S19-4|CP013_HUMAN 16 HVLRQYLDPAqRGVRVLEVASGSGQHAAHFARAFPLAEWQPSDVDQRCLDSIAATTQAQGLTnV 79 567788887756678*******************************************998753 PP >> sp|O14744-2|ANM5_HUMAN Isoform 2 of Protein arginine N-methyltransferase 5 OS=Homo sapiens GN=PRMT5 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.2 0.0 9.7e-05 0.057 23 103 .. 328 417 .. 325 446 .. 0.69 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 9.7e-05 HHHHCHCC...TCSE.EEEET-TTSHH...HHHHHHHTT.C.EEEEEESBHHHHHHHHH.HHHHTTGCEEEEE-STTTTSTTS-EEE CS MTS 23 Lletlpke...lsgk.vlDlGcGaGvl...gaalakesp.eaevtlvdvdarAlesake.nleanklevevvasdvleeveekkfdl 100 Ll+ +p+e ++ + ++ lG+G G+l ++ +ak+ + ++++ +v+++ +A+ ++ +e+ + +v+vv sd+ e v+++k d+ sp|O14744-2|ANM5_HUMAN 328 LLDRVPEEekdTNVQvLMVLGAGRGPLvnaSLRAAKQADrRIKLYAVEKNPNAVVTLENwQFEEWGSQVTVVSSDMREWVAPEKADI 414 56666665433222225569*****994433444444331456999*******865543156666677******************* PP EEE CS MTS 101 ivs 103 ivs sp|O14744-2|ANM5_HUMAN 415 IVS 417 **8 PP >> sp|O14744|ANM5_HUMAN Protein arginine N-methyltransferase 5 OS=Homo sapiens GN=PRMT5 PE=1 SV=4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.2 0.0 0.0001 0.059 23 103 .. 345 434 .. 342 463 .. 0.69 Alignments for each domain: == domain 1 score: 15.2 bits; conditional E-value: 0.0001 HHHHCHCC...TCSE.EEEET-TTSHH...HHHHHHHTT.C.EEEEEESBHHHHHHHHH.HHHHTTGCEEEEE-STTTTSTTS-EEEEE CS MTS 23 Lletlpke...lsgk.vlDlGcGaGvl...gaalakesp.eaevtlvdvdarAlesake.nleanklevevvasdvleeveekkfdliv 102 Ll+ +p+e ++ + ++ lG+G G+l ++ +ak+ + ++++ +v+++ +A+ ++ +e+ + +v+vv sd+ e v+++k d+iv sp|O14744|ANM5_HUMAN 345 LLDRVPEEekdTNVQvLMVLGAGRGPLvnaSLRAAKQADrRIKLYAVEKNPNAVVTLENwQFEEWGSQVTVVSSDMREWVAPEKADIIV 433 56666665433222225569*****994433444444331456999*******865543156666677********************* PP E CS MTS 103 s 103 s sp|O14744|ANM5_HUMAN 434 S 434 8 PP >> tr|H3BQ55|H3BQ55_HUMAN UPF0585 protein C16orf13 (Fragment) OS=Homo sapiens GN=C16orf13 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.5 0.0 8.1e-05 0.048 22 82 .. 7 69 .. 2 84 .. 0.85 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 8.1e-05 HHHHHCHCC.TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.E CS MTS 22 lLletlpke.lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.v 82 +L ++l+ + + +vl +++G G +a++a++ p ae + dvd r l+s ++ +a++l v tr|H3BQ55|H3BQ55_HUMAN 7 VLRQYLDPAqRGVRVLEVASGSGQHAAHFARAFPLAEWQPSDVDQRCLDSIAATTQAQGLTnV 69 66777877656678******************************************9998753 PP >> sp|Q96S19-6|CP013_HUMAN Isoform 6 of UPF0585 protein C16orf13 OS=Homo sapiens GN=C16orf13 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 15.4 0.0 8.4e-05 0.049 21 82 .. 16 79 .. 7 94 .. 0.85 Alignments for each domain: == domain 1 score: 15.4 bits; conditional E-value: 8.4e-05 HHHHHHCHCC.TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.E CS MTS 21 klLletlpke.lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.v 82 ++L ++l+ + + +vl +++G G +a++a++ p ae + dvd r l+s ++ +a++l v sp|Q96S19-6|CP013_HUMAN 16 HVLRQYLDPAqRGVRVLEVASGSGQHAAHFARAFPLAEWQPSDVDQRCLDSIAATTQAQGLTnV 79 567788887756678******************************************9998753 PP >> tr|K7ES84|K7ES84_HUMAN Protein FAM86A OS=Homo sapiens GN=FAM86A PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.2 0.0 0.0002 0.12 31 84 .. 96 149 .. 81 167 .. 0.87 Alignments for each domain: == domain 1 score: 14.2 bits; conditional E-value: 0.0002 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevev 84 ++++vl lG+GaG+ g+a+ k++ + + d + r le + n+ n+l++e+ tr|K7ES84|K7ES84_HUMAN 96 TNRTVLELGSGAGLTGLAICKMCRPRAYIFSDCHSRVLEQLRGNVLLNGLSLEA 149 6789*******************999**********************998543 PP >> sp|Q9HBK9|AS3MT_HUMAN Arsenite methyltransferase OS=Homo sapiens GN=AS3MT PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.0 0.00027 0.16 34 136 .. 73 182 .. 63 193 .. 0.78 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 0.00027 EEEEET-TTSHHHHHHHHHTTC.E.EEEEESBHHHHHHHHHHHHHTTGC...........EEEEE-STTTTSTTS-EEEEEE---STT CS MTS 34 kvlDlGcGaGvlgaalakespeae.vtlvdvdarAlesakenleankle...........vevvasdvleeveekkfdlivsNPPfha 109 +lDlG+G G +l + e vt +d + +e+a++ l + + ++++ + + +++++ d++vsN + sp|Q9HBK9|AS3MT_HUMAN 73 WILDLGSGSGRDCYVLSQLVGEKGhVTGIDMTKGQVEVAEKYLDYHMEKygfqasnvtfiHGYIEKLGEAGIKNESHDIVVSNCVINL 160 49********999999998877655999**99999*99999888777774444544223222233334578999*********99998 PP TCHCHHHHHHHHHHHHHHHEEEEEEEE CS MTS 110 gkatelavaeeliaeAkeaLkegGeLl 136 + +++++eA ++Lk+gGeL+ sp|Q9HBK9|AS3MT_HUMAN 161 VPD-----KQQVLQEAYRVLKHGGELY 182 887.....7999*************98 PP >> sp|Q96G04-2|FA86A_HUMAN Isoform 2 of Protein FAM86A OS=Homo sapiens GN=FAM86A # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.0 0.00024 0.14 31 84 .. 123 176 .. 108 193 .. 0.87 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 0.00024 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevev 84 ++++vl lG+GaG+ g+a+ k++ + + d + r le + n+ n+l++e+ sp|Q96G04-2|FA86A_HUMAN 123 TNRTVLELGSGAGLTGLAICKMCRPRAYIFSDCHSRVLEQLRGNVLLNGLSLEA 176 5789*******************999**********************998543 PP >> tr|K7EP06|K7EP06_HUMAN mRNA cap guanine-N7 methyltransferase OS=Homo sapiens GN=RNMT PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.0 0.0005 0.29 25 81 .. 11 68 .. 3 153 .. 0.73 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 0.0005 HHCHCC..TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC CS MTS 25 etlpke..lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle 81 e++ ++ ++ +vlDlGcG G ++ +k + +++++d+ +++ +++ +e+ k + tr|K7EP06|K7EP06_HUMAN 11 EKVRQKkkRDITVLDLGCGKGGDLLKWKKGRIN-KLVCTDIADVSVKQCQQRYEDMKNR 68 444444234446*********655555554333.59**********9999988876544 PP >> tr|D6RCL3|D6RCL3_HUMAN Probable dimethyladenosine transferase OS=Homo sapiens GN=DIMT1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.6 0.0 0.00015 0.086 31 108 .. 56 132 .. 41 142 .. 0.88 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 0.00015 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTTTSTTS-EEEEEE---ST CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvleeveekkfdlivsNPPfh 108 ++ vl +G G+G ++++l+++ ++ v++++ d r ++ ++ ++ + ++ ++v+ dvl++ fd+ v N P++ tr|D6RCL3|D6RCL3_HUMAN 56 PTDVVLEVGPGTGNMTVKLLEKAKK--VVACELDPRLVAELHKRVQGTPVAskLQVLVGDVLKTDL-PFFDTCVANLPYQ 132 56679****************9888..9******************99998889********9888.7999999998876 PP >> sp|Q96G04|FA86A_HUMAN Protein FAM86A OS=Homo sapiens GN=FAM86A PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.7 0.0 0.00029 0.17 31 84 .. 157 210 .. 142 227 .. 0.87 Alignments for each domain: == domain 1 score: 13.7 bits; conditional E-value: 0.00029 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevev 84 ++++vl lG+GaG+ g+a+ k++ + + d + r le + n+ n+l++e+ sp|Q96G04|FA86A_HUMAN 157 TNRTVLELGSGAGLTGLAICKMCRPRAYIFSDCHSRVLEQLRGNVLLNGLSLEA 210 5789*******************999**********************998543 PP >> tr|F2Z2W7|F2Z2W7_HUMAN tRNA (uracil-5-)-methyltransferase homolog A OS=Homo sapiens GN=TRMT2A PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 0.0012 0.72 31 51 .. 432 452 .. 403 457 .. 0.78 2 ? 0.5 0.0 3.2 1.8e+03 58 85 .. 475 503 .. 461 520 .. 0.79 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.0012 TCSEEEEET-TTSHHHHHHHH CS MTS 31 lsgkvlDlGcGaGvlgaalak 51 + vlD++cG+G +g+ala+ tr|F2Z2W7|F2Z2W7_HUMAN 432 AGSMVLDVCCGTGTIGLALAR 452 5667**************986 PP == domain 2 score: 0.5 bits; conditional E-value: 3.2 EEEEESBHHHHHHHHHHHHHTTGC.EEEE CS MTS 58 vtlvdvdarAlesakenleankle.vevv 85 v v+ +A+e a+ n+++n+l+ ve++ tr|F2Z2W7|F2Z2W7_HUMAN 475 VIGVELCPEAVEDARVNAQDNELSnVEFH 503 667778889*************9977765 PP >> tr|H3BNT3|H3BNT3_HUMAN UPF0585 protein C16orf13 (Fragment) OS=Homo sapiens GN=C16orf13 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.6 0.0 0.00015 0.09 31 82 .. 9 61 .. 1 123 [. 0.83 Alignments for each domain: == domain 1 score: 14.6 bits; conditional E-value: 0.00015 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.E CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.v 82 + +vl +++G G +a++a++ p ae + dvd r l+s ++ +a++l v tr|H3BNT3|H3BNT3_HUMAN 9 RGVRVLEVASGSGQHAAHFARAFPLAEWQPSDVDQRCLDSIAATTQAQGLTnV 61 5668*******************************************998763 PP >> sp|Q9BV44|THUM3_HUMAN THUMP domain-containing protein 3 OS=Homo sapiens GN=THUMPD3 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 0.5 0.0 3.1 1.8e+03 60 93 .. 1 34 [. 1 42 [. 0.89 2 ? -0.0 0.0 4.8 2.8e+03 127 148 .. 86 107 .. 69 123 .. 0.80 3 ? 9.4 0.0 0.0061 3.6 35 111 .. 323 399 .. 310 418 .. 0.87 Alignments for each domain: == domain 1 score: 0.5 bits; conditional E-value: 3.1 EEESBHHHHHHHHHHHHHTTGCEEEEE-STTTTS CS MTS 60 lvdvdarAlesakenleanklevevvasdvleev 93 ++d++ + ++ nl++n+ +v+v++sd+ +e sp|Q9BV44|THUM3_HUMAN 1 MCDIEEATNQLLDVNLHENQKSVQVTESDLGSES 34 7899999999999****************97765 PP == domain 2 score: -0.0 bits; conditional E-value: 4.8 HHEEEEEEEEEEEETTSCHHHH CS MTS 127 eaLkegGeLliVanrklgyesl 148 ++L++ +L++V++++++y+ + sp|Q9BV44|THUM3_HUMAN 86 HCLRSVDNLFVVVQEFQDYQFK 107 67889999*********99865 PP == domain 3 score: 9.4 bits; conditional E-value: 0.0061 EEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTTSTTS-EEEEEE---STTTC CS MTS 35 vlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasdvleeveekkfdlivsNPPfhagk 111 ++D cG+G++ ++ a e+++ + d++ A++ a +n+++ + ++ + ++ + +++ ++N P+++g+ sp|Q9BV44|THUM3_HUMAN 323 IVDPMCGTGAIPIEGATEWSDCFHIAGDNNPLAVNRAANNIASLLTKSQIKEGKPSWGLPIDAVQWDICNLPLRTGS 399 89999****************999999***************99999998888888888888888888888888776 PP >> tr|H3BMF3|H3BMF3_HUMAN UPF0585 protein C16orf13 (Fragment) OS=Homo sapiens GN=C16orf13 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.5 0.0 0.00016 0.095 29 82 .. 7 62 .. 1 120 [. 0.84 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 0.00016 CC.TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.E CS MTS 29 ke.lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.v 82 + + +vl +++G G +a++a++ p ae + dvd r l+s ++ +a++l v tr|H3BMF3|H3BMF3_HUMAN 7 PAqRGVRVLEVASGSGQHAAHFARAFPLAEWQPSDVDQRCLDSIAATTQAQGLTnV 62 4435668*******************************************998753 PP >> tr|C9J0F2|C9J0F2_HUMAN Protein-L-isoaspartate(D-aspartate) O-methyltransferase (Fragment) OS=Homo sapiens GN=PCMT1 P # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.1 0.1 0.00022 0.13 21 54 .. 39 70 .. 32 95 .. 0.80 Alignments for each domain: == domain 1 score: 14.1 bits; conditional E-value: 0.00022 HHHHHHCHCCTCSEEEEET-TTSHHHHHHHHHTT CS MTS 21 klLletlpkelsgkvlDlGcGaGvlgaalakesp 54 +lL ++l++ k+lD+G+G G+l+a +a++ tr|C9J0F2|C9J0F2_HUMAN 39 ELLFDQLHE--GAKALDVGSGSGILTACFARMVG 70 688888888..6789************9999865 PP >> sp|Q8N7N1|F86B1_HUMAN Protein FAM86B1 OS=Homo sapiens GN=FAM86B1 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.3 0.0 0.00037 0.21 31 84 .. 123 176 .. 108 193 .. 0.88 Alignments for each domain: == domain 1 score: 13.3 bits; conditional E-value: 0.00037 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevev 84 ++++vl lG+GaG+ g+a+ k++ + + d + r le + n+ n+l++e+ sp|Q8N7N1|F86B1_HUMAN 123 INRTVLELGSGAGLTGLAICKMCRPRAYIFSDPHSRVLEQLRGNVLLNGLSLEA 176 7889*******************999**********************998554 PP >> tr|H7C4Z8|H7C4Z8_HUMAN Methyltransferase-like protein 2B (Fragment) OS=Homo sapiens GN=METTL2B PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.0 0.00027 0.16 31 78 .. 174 223 .. 163 235 .] 0.76 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 0.00027 TCSEEEEET-TTSHHHHHHHHHT..TC.EEEEEESBHHHHHHHHHHHHHT CS MTS 31 lsgkvlDlGcGaGvlgaalakes..peaevtlvdvdarAlesakenlean 78 ++ ++l +GcG+G +++ + p + v ++d + A+e+ ++n e tr|H7C4Z8|H7C4Z8_HUMAN 174 ATYRILEVGCGVGNTVFPILQTNndPGLFVYCCDFSSTAIELVQTNSEYD 223 55689********8777777665115566****************98765 PP >> tr|H0Y2T8|H0Y2T8_HUMAN tRNA (cytosine(38)-C(5))-methyltransferase (Fragment) OS=Homo sapiens GN=TRDMT1 PE=3 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.4 0.0 0.00034 0.2 54 107 .. 5 58 .. 2 70 .. 0.92 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 0.00034 TC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTTSTTS-EEEEEE---S CS MTS 54 peaevtlvdvdarAlesakenleanklevevvasdvleeveekkfdlivsNPPf 107 p + v ++dv++ A e+ k n+ +++l +++++ lee++ +fd+i++ PP tr|H0Y2T8|H0Y2T8_HUMAN 5 PAQVVAAIDVNTVANEVYKYNFPHTQLLAKTIEGITLEEFDRLSFDMILMSPPC 58 5566899*********************************************96 PP >> sp|Q8N6F8|WBS27_HUMAN Williams-Beuren syndrome chromosomal region 27 protein OS=Homo sapiens GN=WBSCR27 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.0 0.00043 0.25 22 73 .. 57 108 .. 50 137 .. 0.74 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 0.00043 HHHHHCHCC.TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHH CS MTS 22 lLletlpke.lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesake 73 L ++lp +s +lD++cG+G+++a+l + ++++ vd + le a++ sp|Q8N6F8|WBS27_HUMAN 57 CLTQALPGPpHSALILDVACGTGLVAAELRA-PGFLQLHGVDGSPGMLEQAQA 108 56777777778888*************9976.344568888877777777665 PP >> sp|Q9BV86|NTM1A_HUMAN N-terminal Xaa-Pro-Lys N-methyltransferase 1 OS=Homo sapiens GN=NTMT1 PE=1 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.4 0.0 0.00035 0.21 31 137 .. 61 165 .. 34 182 .. 0.74 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 0.00035 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTTST..TS-EEEEEE---STTTCHCHHH CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasdvleeve..ekkfdlivsNPPfhagkatela 116 + +lD G+G+G ++ l+ + ev++vd+ l ak+ l +++ +v+ + + +l++++ ++++d+i + g+ +++ sp|Q9BV86|NTM1A_HUMAN 61 GTSCALDCGAGIGRITKRLLLPLFR-EVDMVDITEDFLVQAKTYLGEEGKRVRNYFCCGLQDFTpePDSYDVIWIQWVI--GHL-TDQ 144 23349************99987777.7********************9999888888888877644789****987544..443.446 PP HHHHHHHHHHHHEEEEEEEEE CS MTS 117 vaeeliaeAkeaLkegGeLli 137 e+++ k L+++G ++i sp|Q9BV86|NTM1A_HUMAN 145 HLAEFLRRCKGSLRPNGIIVI 165 677899999999999996655 PP >> tr|E9PN63|E9PN63_HUMAN Protein FAM86B1 OS=Homo sapiens GN=FAM86B1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.0 0.00045 0.26 31 84 .. 157 210 .. 142 226 .. 0.88 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 0.00045 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevev 84 ++++vl lG+GaG+ g+a+ k++ + + d + r le + n+ n+l++e+ tr|E9PN63|E9PN63_HUMAN 157 INRTVLELGSGAGLTGLAICKMCRPRAYIFSDPHSRVLEQLRGNVLLNGLSLEA 210 7889*******************999*********************9998554 PP >> tr|H3BN86|H3BN86_HUMAN Methyltransferase-like protein 9 (Fragment) OS=Homo sapiens GN=METTL9 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.5 0.0 0.097 57 6 26 .. 27 47 .. 23 54 .. 0.88 2 ? 6.6 0.0 0.045 26 28 65 .. 102 137 .. 88 166 .. 0.76 Alignments for each domain: == domain 1 score: 5.5 bits; conditional E-value: 0.097 EETTSTTTTS--HHHHHHHHH CS MTS 6 tlpgvFskdklDkGsklLlet 26 +l++vF + lD+G++++l++ tr|H3BN86|H3BN86_HUMAN 27 SLQAVFVQSYLDQGTQIFLNN 47 6789*************9986 PP == domain 2 score: 6.6 bits; conditional E-value: 0.045 HCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBH CS MTS 28 pkelsgkvlDlGcGaGvlgaalakespeaevtlvdvda 65 p+ +++++lDlG+G G ++ + + +e + +++ + tr|H3BN86|H3BN86_HUMAN 102 PDWKTHRLLDLGAGDGEVTKIMSPHFEE--IYATELSE 137 3337889**********99888777666..55555554 PP >> tr|B7Z972|B7Z972_HUMAN Protein-L-isoaspartate O-methyltransferase OS=Homo sapiens GN=PCMT1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.4 0.2 0.00036 0.21 21 77 .. 35 90 .. 29 146 .. 0.74 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 0.00036 HHHHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.E.EEEEESBHHHHHHHHHHHHH CS MTS 21 klLletlpkelsgkvlDlGcGaGvlgaalakespeae.vtlvdvdarAlesakenlea 77 +lL ++l++ k+lD+G+G G+l+a +a++ + v +d ++ ++ + +n+++ tr|B7Z972|B7Z972_HUMAN 35 ELLFDQLHE--GAKALDVGSGSGILTACFARMVGCTGkVIGIDHIKELVDDSVNNVRK 90 688888888..6789**************99876543366666655555555555555 PP >> sp|Q8N6Q8|MET25_HUMAN Methyltransferase-like protein 25 OS=Homo sapiens GN=METTL25 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.5 0.0 0.0027 1.6 32 69 .. 175 211 .. 155 232 .. 0.71 2 ? 0.9 0.1 2.4 1.4e+03 60 94 .. 232 266 .. 219 273 .. 0.82 Alignments for each domain: == domain 1 score: 10.5 bits; conditional E-value: 0.0027 CSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHH CS MTS 32 sgkvlDlGcGaGvlgaalakespeaevtlvdvdarAle 69 ++v+DlG+G G+l+ l ++ +v +d + + sp|Q8N6Q8|MET25_HUMAN 175 IKQVIDLGSGKGYLSSFLSLKYGL-KVYGIDSSNTNTH 211 468************999887654.6777776665555 PP == domain 2 score: 0.9 bits; conditional E-value: 2.4 EEESBHHHHHHHHHHHHHTTGCEEEEE-STTTTST CS MTS 60 lvdvdarAlesakenleanklevevvasdvleeve 94 +dv+ Al++ake +nk++ ++ +++v+++ + sp|Q8N6Q8|MET25_HUMAN 232 RLDVNGLALKMAKERKVQNKVKNKADTEEVFNNSP 266 579999**************998888888877765 PP >> sp|Q9UNQ2|DIM1_HUMAN Probable dimethyladenosine transferase OS=Homo sapiens GN=DIMT1 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.0 0.00046 0.27 31 110 .. 56 134 .. 43 176 .. 0.84 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 0.00046 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTTTSTTS-EEEEEE---STTT CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvleeveekkfdlivsNPPfhag 110 ++ vl +G G+G ++++l+++ ++ v++++ d r ++ ++ ++ + ++ ++v+ dvl++ fd+ v N P++ + sp|Q9UNQ2|DIM1_HUMAN 56 PTDVVLEVGPGTGNMTVKLLEKAKK--VVACELDPRLVAELHKRVQGTPVAskLQVLVGDVLKTDL-PFFDTCVANLPYQIS 134 46679****************9888..9******************9999888*********9988.899***999998755 PP >> sp|O43148|MCES_HUMAN mRNA cap guanine-N7 methyltransferase OS=Homo sapiens GN=RNMT PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 0.0012 0.69 26 80 .. 190 245 .. 181 331 .. 0.74 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 0.0012 HCHCC..TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTG CS MTS 26 tlpke..lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankl 80 ++ ++ ++ +vlDlGcG G ++ +k + +++++d+ +++ +++ +e+ k sp|O43148|MCES_HUMAN 190 KVRQKkkRDITVLDLGCGKGGDLLKWKKGRIN-KLVCTDIADVSVKQCQQRYEDMKN 245 44444234446*********655555553333.599****99999999998887654 PP >> sp|Q9BUU2|MET22_HUMAN Methyltransferase-like protein 22 OS=Homo sapiens GN=METTL22 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.1 0.00085 0.5 19 80 .. 189 252 .. 183 269 .. 0.80 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.00085 HHHHHHHHCHCC....TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTG CS MTS 19 GsklLletlpke....lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankl 80 G+ lL++++ + + ++l lG+G+G+ ++ +a + + v ++dv a l ++++n++ n + sp|Q9BUU2|MET22_HUMAN 189 GALLLADYILFRqdlfRGCTALELGAGTGLASIIAATMART--VYCTDVGADLLSMCQRNIALNSH 252 666666665443345555579*********99999998777..9*****************99975 PP >> tr|E9PQV7|E9PQV7_HUMAN Protein FAM86B2 (Fragment) OS=Homo sapiens GN=FAM86B2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 0.00061 0.36 31 84 .. 123 176 .. 108 193 .. 0.87 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 0.00061 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevev 84 ++++vl lG+GaG+ g+a+ k++ + + d + r le + n+ n+l++e+ tr|E9PQV7|E9PQV7_HUMAN 123 INRTVLELGSGAGLTGLAICKMCRPRAYIFSDPHSRILEQLRGNVLLNGLSLEA 176 7889*******************999*********************9998554 PP >> tr|H7BXI9|H7BXI9_HUMAN Protein FAM86B2 OS=Homo sapiens GN=FAM86B2 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 0.00061 0.36 31 84 .. 123 176 .. 108 193 .. 0.87 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 0.00061 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevev 84 ++++vl lG+GaG+ g+a+ k++ + + d + r le + n+ n+l++e+ tr|H7BXI9|H7BXI9_HUMAN 123 INRTVLELGSGAGLTGLAICKMCRPRAYIFSDPHSRILEQLRGNVLLNGLSLEA 176 7889*******************999*********************9998554 PP >> tr|H0YIW7|H0YIW7_HUMAN Methyltransferase-like protein 25 (Fragment) OS=Homo sapiens GN=METTL25 PE=4 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.0 0.0 0.00048 0.28 32 69 .. 134 170 .. 110 188 .. 0.71 Alignments for each domain: == domain 1 score: 13.0 bits; conditional E-value: 0.00048 CSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHH CS MTS 32 sgkvlDlGcGaGvlgaalakespeaevtlvdvdarAle 69 ++v+DlG+G G+l+ l ++ +v +d + + tr|H0YIW7|H0YIW7_HUMAN 134 IKQVIDLGSGKGYLSSFLSLKYGL-KVYGIDSSNTNTH 170 468************999887664.6777776665554 PP >> sp|O43148-2|MCES_HUMAN Isoform 2 of mRNA cap guanine-N7 methyltransferase OS=Homo sapiens GN=RNMT # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 0.0013 0.76 26 80 .. 190 245 .. 181 331 .. 0.74 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.0013 HCHCC..TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTG CS MTS 26 tlpke..lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankl 80 ++ ++ ++ +vlDlGcG G ++ +k + +++++d+ +++ +++ +e+ k sp|O43148-2|MCES_HUMAN 190 KVRQKkkRDITVLDLGCGKGGDLLKWKKGRIN-KLVCTDIADVSVKQCQQRYEDMKN 245 44444234446*********655555553333.599****99999999998887654 PP >> sp|P22061|PIMT_HUMAN Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens GN=PCMT1 PE=1 SV=4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.1 0.00053 0.31 21 77 .. 70 125 .. 66 181 .. 0.74 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.00053 HHHHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.E.EEEEESBHHHHHHHHHHHHH CS MTS 21 klLletlpkelsgkvlDlGcGaGvlgaalakespeae.vtlvdvdarAlesakenlea 77 +lL ++l++ k+lD+G+G G+l+a +a++ + v +d ++ ++ + +n+++ sp|P22061|PIMT_HUMAN 70 ELLFDQLHE--GAKALDVGSGSGILTACFARMVGCTGkVIGIDHIKELVDDSVNNVRK 125 688888888..6789**************99876543366666555555555555555 PP >> sp|Q7Z2T5-2|TRM1L_HUMAN Isoform 2 of TRMT1-like protein OS=Homo sapiens GN=TRMT1L # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 0.00064 0.38 35 84 .. 123 173 .. 106 214 .. 0.83 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 0.00064 EEEET-TTSHHHHHHHHHTTC.E.EEEEESBHHHHHHHHHHHHHTTGCEEE CS MTS 35 vlDlGcGaGvlgaalakespeae.vtlvdvdarAlesakenleanklevev 84 lD +G++g++ ak+ +a vt+ d + +++++ +en++ nkl+v v sp|Q7Z2T5-2|TRM1L_HUMAN 123 CLDAFGATGIMGLQWAKHLGNAVkVTINDLNENSVTLIQENCHLNKLKVVV 173 66766668******9999887655**********************99654 PP >> sp|P22061-2|PIMT_HUMAN Isoform 2 of Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens GN=PCMT1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.8 0.1 0.00054 0.31 21 77 .. 70 125 .. 66 181 .. 0.74 Alignments for each domain: == domain 1 score: 12.8 bits; conditional E-value: 0.00054 HHHHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.E.EEEEESBHHHHHHHHHHHHH CS MTS 21 klLletlpkelsgkvlDlGcGaGvlgaalakespeae.vtlvdvdarAlesakenlea 77 +lL ++l++ k+lD+G+G G+l+a +a++ + v +d ++ ++ + +n+++ sp|P22061-2|PIMT_HUMAN 70 ELLFDQLHE--GAKALDVGSGSGILTACFARMVGCTGkVIGIDHIKELVDDSVNNVRK 125 688888888..6789**************99876543366666555555555555555 PP >> sp|P0C5J1|F86B2_HUMAN Protein FAM86B2 OS=Homo sapiens GN=FAM86B2 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.3 0.0 0.00075 0.44 31 84 .. 157 210 .. 142 226 .. 0.88 Alignments for each domain: == domain 1 score: 12.3 bits; conditional E-value: 0.00075 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevev 84 ++++vl lG+GaG+ g+a+ k++ + + d + r le + n+ n+l++e+ sp|P0C5J1|F86B2_HUMAN 157 INRTVLELGSGAGLTGLAICKMCRPRAYIFSDPHSRILEQLRGNVLLNGLSLEA 210 7889*******************999********************99998554 PP >> tr|F8VZA8|F8VZA8_HUMAN Methyltransferase-like protein 25 (Fragment) OS=Homo sapiens GN=METTL25 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.7 0.0 0.0006 0.35 32 72 .. 175 214 .. 152 235 .. 0.71 Alignments for each domain: == domain 1 score: 12.7 bits; conditional E-value: 0.0006 CSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHH CS MTS 32 sgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesak 72 ++v+DlG+G G+l+ l ++ +v +d + + a+ tr|F8VZA8|F8VZA8_HUMAN 175 IKQVIDLGSGKGYLSSFLSLKYGL-KVYGIDSSNTNTHGAE 214 468************999887765.6777777666555554 PP >> sp|Q9H867-1|MT21D_HUMAN Isoform 1 of Protein-lysine methyltransferase METTL21D OS=Homo sapiens GN=METTL21D # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.9 0.1 0.00049 0.29 31 77 .. 67 112 .. 45 128 .. 0.72 Alignments for each domain: == domain 1 score: 12.9 bits; conditional E-value: 0.00049 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESB.HHHHHHHHHHHHH CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvd.arAlesakenlea 77 +++vl lG+G+G++g+++a ++ +++d + + l + n+++ sp|Q9H867-1|MT21D_HUMAN 67 SRRSVLELGSGTGAVGLMAATLGADV--VVTDLEeLQDLLKMNINMNK 112 4578*****************99995..55554303444444444444 PP >> tr|H3BTF5|H3BTF5_HUMAN Methyltransferase-like protein 22 OS=Homo sapiens GN=METTL22 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.5 0.1 0.00066 0.39 19 80 .. 133 196 .. 127 214 .. 0.80 Alignments for each domain: == domain 1 score: 12.5 bits; conditional E-value: 0.00066 HHHHHHHHCHCC....TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTG CS MTS 19 GsklLletlpke....lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankl 80 G+ lL++++ + + ++l lG+G+G+ ++ +a + + v ++dv a l ++++n++ n + tr|H3BTF5|H3BTF5_HUMAN 133 GALLLADYILFRqdlfRGCTALELGAGTGLASIIAATMART--VYCTDVGADLLSMCQRNIALNSH 196 666666665443345555579*********99999998777..9*****************99975 PP >> sp|Q9NVM4-4|ANM7_HUMAN Isoform 4 of Protein arginine N-methyltransferase 7 OS=Homo sapiens GN=PRMT7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.5 0.0 0.0058 3.4 28 56 .. 60 89 .. 50 133 .. 0.64 2 ? 0.8 0.0 2.6 1.5e+03 41 81 .. 409 449 .. 387 465 .. 0.62 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 0.0058 HCC.TCSEEEEET-TTSHHHHHHHHHTTC. CS MTS 28 pke.lsgkvlDlGcGaGvlgaalakespea 56 +++ ++ vlD+G+G+G+l++++ + + sp|Q9NVM4-4|ANM7_HUMAN 60 KDRgQKALVLDIGTGTGLLSMMAVTAGADF 89 554456669************998877764 PP == domain 2 score: 0.8 bits; conditional E-value: 2.6 TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC CS MTS 41 GaGvlgaalakespeaevtlvdvdarAlesakenleankle 81 G l +la++ +v v+ +a++ ++ ++ ++an+le sp|Q9NVM4-4|ANM7_HUMAN 409 SDGSLLSVLAHHLGVEQVFTVESSAASHKLLRKIFKANHLE 449 44455555555555555555666666666666666665555 PP >> tr|H3BNC0|H3BNC0_HUMAN Protein arginine N-methyltransferase 7 OS=Homo sapiens GN=PRMT7 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.5 0.0 0.0058 3.4 28 56 .. 60 89 .. 50 133 .. 0.64 2 ? 0.8 0.0 2.6 1.5e+03 41 81 .. 409 449 .. 387 465 .. 0.62 Alignments for each domain: == domain 1 score: 9.5 bits; conditional E-value: 0.0058 HCC.TCSEEEEET-TTSHHHHHHHHHTTC. CS MTS 28 pke.lsgkvlDlGcGaGvlgaalakespea 56 +++ ++ vlD+G+G+G+l++++ + + tr|H3BNC0|H3BNC0_HUMAN 60 KDRgQKALVLDIGTGTGLLSMMAVTAGADF 89 554456669************998877764 PP == domain 2 score: 0.8 bits; conditional E-value: 2.6 TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC CS MTS 41 GaGvlgaalakespeaevtlvdvdarAlesakenleankle 81 G l +la++ +v v+ +a++ ++ ++ ++an+le tr|H3BNC0|H3BNC0_HUMAN 409 SDGSLLSVLAHHLGVEQVFTVESSAASHKLLRKIFKANHLE 449 44455555555555555555666666666666666665555 PP >> sp|Q9H1A3-2|METL9_HUMAN Isoform 2 of Methyltransferase-like protein 9 OS=Homo sapiens GN=METTL9 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.0 0.14 80 6 26 .. 67 87 .. 63 94 .. 0.88 2 ? 5.9 0.0 0.073 43 29 65 .. 143 177 .. 129 205 .. 0.76 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.14 EETTSTTTTS--HHHHHHHHH CS MTS 6 tlpgvFskdklDkGsklLlet 26 +l++vF + lD+G++++l++ sp|Q9H1A3-2|METL9_HUMAN 67 SLQAVFVQSYLDQGTQIFLNN 87 6789*************9986 PP == domain 2 score: 5.9 bits; conditional E-value: 0.073 CCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBH CS MTS 29 kelsgkvlDlGcGaGvlgaalakespeaevtlvdvda 65 + +++++lDlG+G G ++ + + +e + +++ + sp|Q9H1A3-2|METL9_HUMAN 143 DWKTHRLLDLGAGDGEVTKIMSPHFEE--IYATELSE 177 337889**********99888777666..55555554 PP >> sp|P46597|ASMT_HUMAN Acetylserotonin O-methyltransferase OS=Homo sapiens GN=ASMT PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 0.00072 0.42 35 93 .. 183 241 .. 168 256 .. 0.82 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.00072 EEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTS CS MTS 35 vlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdvleev 93 + DlG GaG+l+ ++ + +p ++t++d+ + ak+ ++ ++ e +++ + d +++ sp|P46597|ASMT_HUMAN 183 MCDLGGGAGALAKECMSLYPGCKITVFDIPE-VVWTAKQHFSFQEEEqIDFQEGDFFKDP 241 68**************************965.6888888887777666888888877665 PP >> sp|Q9H1A3|METL9_HUMAN Methyltransferase-like protein 9 OS=Homo sapiens GN=METTL9 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 5.0 0.0 0.14 81 6 26 .. 67 87 .. 63 94 .. 0.88 2 ? 5.9 0.0 0.073 43 29 65 .. 143 177 .. 129 205 .. 0.76 Alignments for each domain: == domain 1 score: 5.0 bits; conditional E-value: 0.14 EETTSTTTTS--HHHHHHHHH CS MTS 6 tlpgvFskdklDkGsklLlet 26 +l++vF + lD+G++++l++ sp|Q9H1A3|METL9_HUMAN 67 SLQAVFVQSYLDQGTQIFLNN 87 6789*************9986 PP == domain 2 score: 5.9 bits; conditional E-value: 0.073 CCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBH CS MTS 29 kelsgkvlDlGcGaGvlgaalakespeaevtlvdvda 65 + +++++lDlG+G G ++ + + +e + +++ + sp|Q9H1A3|METL9_HUMAN 143 DWKTHRLLDLGAGDGEVTKIMSPHFEE--IYATELSE 177 337889**********99888777666..55555554 PP >> tr|H3BSS9|H3BSS9_HUMAN Protein arginine N-methyltransferase 7 (Fragment) OS=Homo sapiens GN=PRMT7 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 0.00071 0.41 27 77 .. 59 113 .. 49 134 .. 0.62 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.00071 CHCC.TCSEEEEET-TTSHHHHHHHHHTTC.E..EEEEE.SBHHHHHHHHHHHHH CS MTS 27 lpke.lsgkvlDlGcGaGvlgaalakespeae..vtlvd.vdarAlesakenlea 77 ++++ ++ vlD+G+G+G+l++++ + + ++++ +A+++ ++n + tr|H3BSS9|H3BSS9_HUMAN 59 VKDRgQKALVLDIGTGTGLLSMMAVTAGADFCyaIEVFKpMADAAVKIVEKNGFS 113 555555667*************998887775322333331233445555555444 PP >> tr|J3KP72|J3KP72_HUMAN Protein-L-isoaspartate O-methyltransferase OS=Homo sapiens GN=PCMT1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 0.00086 0.5 21 75 .. 128 181 .. 123 217 .. 0.70 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 0.00086 HHHHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.E.EEEEESBHHHHHHHHHHH CS MTS 21 klLletlpkelsgkvlDlGcGaGvlgaalakespeae.vtlvdvdarAlesakenl 75 +lL ++l++ k+lD+G+G G+l+a +a++ + v +d ++ ++ + +n+ tr|J3KP72|J3KP72_HUMAN 128 ELLFDQLHE--GAKALDVGSGSGILTACFARMVGCTGkVIGIDHIKELVDDSVNNV 181 688888888..6789*************9998765433555555555555555555 PP >> tr|H7BY58|H7BY58_HUMAN Protein-L-isoaspartate O-methyltransferase OS=Homo sapiens GN=PCMT1 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.1 0.0 0.00086 0.51 21 75 .. 128 181 .. 123 217 .. 0.70 Alignments for each domain: == domain 1 score: 12.1 bits; conditional E-value: 0.00086 HHHHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.E.EEEEESBHHHHHHHHHHH CS MTS 21 klLletlpkelsgkvlDlGcGaGvlgaalakespeae.vtlvdvdarAlesakenl 75 +lL ++l++ k+lD+G+G G+l+a +a++ + v +d ++ ++ + +n+ tr|H7BY58|H7BY58_HUMAN 128 ELLFDQLHE--GAKALDVGSGSGILTACFARMVGCTGkVIGIDHIKELVDDSVNNV 181 688888888..6789*************9998765433555555555555555555 PP >> sp|Q8TEA1|NSUN6_HUMAN Putative methyltransferase NSUN6 OS=Homo sapiens GN=NSUN6 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.3 0.0 0.0063 3.7 21 98 .. 224 303 .. 218 317 .. 0.79 2 ? 0.7 0.0 2.9 1.7e+03 117 136 .. 350 369 .. 342 374 .. 0.84 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 0.0063 HHHHHHCHCCTCSEEEEET-TTSHHHHHHHHH.TTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTTS-E CS MTS 21 klLletlpkelsgkvlDlGcGaGvlgaalake.speaevtlvdvdarAlesakenleankle.vevvasdvleeveekkf 98 +l + l+ + +k+lDl++ G ++++a+ +++ ev ++d+ ++ +e k+n+ +l+ ++++ d++++v+ + + sp|Q8TEA1|NSUN6_HUMAN 224 ALVSHVLNPQPGEKILDLCAAPGGKTTHIAALmHDQGEVIALDKIFNKVEKIKQNALLLGLNsIRAFCFDGTKAVKLDMV 303 4444556666999******9998877777665155667***********************999***9999999984444 PP == domain 2 score: 0.7 bits; conditional E-value: 2.9 HHHHHHHHHHHHEEEEEEEE CS MTS 117 vaeeliaeAkeaLkegGeLl 136 + ++l+++A + Lk++G L+ sp|Q8TEA1|NSUN6_HUMAN 350 LQRKLFTAAVQLLKPEGVLV 369 56799************996 PP >> tr|I3L2J5|I3L2J5_HUMAN Methyltransferase-like protein 22 (Fragment) OS=Homo sapiens GN=METTL22 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.2 0.2 0.00082 0.48 35 80 .. 5 48 .. 2 67 .. 0.88 Alignments for each domain: == domain 1 score: 12.2 bits; conditional E-value: 0.00082 EEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTG CS MTS 35 vlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankl 80 +l lG+G+G+ ++ +a + + v ++dv a l ++++n++ n + tr|I3L2J5|I3L2J5_HUMAN 5 ALELGAGTGLASIIAATMART--VYCTDVGADLLSMCQRNIALNSH 48 689*******99999998777..9*****************99975 PP >> tr|H3BPZ8|H3BPZ8_HUMAN Protein arginine N-methyltransferase 7 (Fragment) OS=Homo sapiens GN=PRMT7 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 0.0012 0.73 27 75 .. 59 111 .. 49 134 .. 0.62 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.0012 CHCC.TCSEEEEET-TTSHHHHHHHHHTTC.E..EEEEE.SBHHHHHHHHHHH CS MTS 27 lpke.lsgkvlDlGcGaGvlgaalakespeae..vtlvd.vdarAlesakenl 75 ++++ ++ vlD+G+G+G+l++++ + + ++++ +A+++ ++n tr|H3BPZ8|H3BPZ8_HUMAN 59 VKDRgQKALVLDIGTGTGLLSMMAVTAGADFCyaIEVFKpMADAAVKIVEKNG 111 555545667*************9988877743223333212233455555554 PP >> sp|Q9H867-5|MT21D_HUMAN Isoform 5 of Protein-lysine methyltransferase METTL21D OS=Homo sapiens GN=METTL21D # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 0.00072 0.42 32 78 .. 68 113 .. 46 142 .. 0.74 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.00072 CSEEEEET-TTSHHHHHHHHHTTC.EEEEEESB.HHHHHHHHHHHHHT CS MTS 32 sgkvlDlGcGaGvlgaalakespeaevtlvdvd.arAlesakenlean 78 +++vl lG+G+G++g+++a ++ +++d + + l + n++++ sp|Q9H867-5|MT21D_HUMAN 68 RRSVLELGSGTGAVGLMAATLGADV--VVTDLEeLQDLLKMNINMNKH 113 578*****************99995..555543034444444444444 PP >> sp|Q7Z2T5|TRM1L_HUMAN TRMT1-like protein OS=Homo sapiens GN=TRMT1L PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.1 0.0018 1 35 84 .. 279 329 .. 263 349 .. 0.80 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.0018 EEEET-TTSHHHHHHHHHTTC.E.EEEEESBHHHHHHHHHHHHHTTGCEEE CS MTS 35 vlDlGcGaGvlgaalakespeae.vtlvdvdarAlesakenleanklevev 84 lD +G++g++ ak+ +a vt+ d + +++++ +en++ nkl+v v sp|Q7Z2T5|TRM1L_HUMAN 279 CLDAFGATGIMGLQWAKHLGNAVkVTINDLNENSVTLIQENCHLNKLKVVV 329 66666668******9999887655**********************99654 PP >> tr|C9JH95|C9JH95_HUMAN Histone-lysine N-methyltransferase, H3 lysine-79-specific (Fragment) OS=Homo sapiens GN=DOT1L # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.0 0.0015 0.85 8 56 .. 109 156 .. 107 180 .. 0.79 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.0015 TTSTTTTS--HHHHHHHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC. CS MTS 8 pgvFskdklDkGsklLletlpkelsgkvlDlGcGaGvlgaalakespea 56 p v+ ++++D ++ +++ ++ + ++ +DlG+G+G + +++a++++ tr|C9JH95|C9JH95_HUMAN 109 PEVYGETSFDLVAQ-MIDEIKMTDDDLFVDLGSGVGQVVLQVAAATNCK 156 78999999999888.578899988999*********9999888766544 PP >> sp|Q9NVM4|ANM7_HUMAN Protein arginine N-methyltransferase 7 OS=Homo sapiens GN=PRMT7 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.1 0.0 0.0075 4.4 28 56 .. 60 89 .. 50 133 .. 0.64 2 ? 0.4 0.0 3.5 2e+03 41 81 .. 409 449 .. 388 464 .. 0.62 Alignments for each domain: == domain 1 score: 9.1 bits; conditional E-value: 0.0075 HCC.TCSEEEEET-TTSHHHHHHHHHTTC. CS MTS 28 pke.lsgkvlDlGcGaGvlgaalakespea 56 +++ ++ vlD+G+G+G+l++++ + + sp|Q9NVM4|ANM7_HUMAN 60 KDRgQKALVLDIGTGTGLLSMMAVTAGADF 89 554456669************998877764 PP == domain 2 score: 0.4 bits; conditional E-value: 3.5 TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC CS MTS 41 GaGvlgaalakespeaevtlvdvdarAlesakenleankle 81 G l +la++ +v v+ +a++ ++ ++ ++an+le sp|Q9NVM4|ANM7_HUMAN 409 SDGSLLSVLAHHLGVEQVFTVESSAASHKLLRKIFKANHLE 449 34444455555555555555555555555555555555555 PP >> sp|Q9H867|MT21D_HUMAN Protein-lysine methyltransferase METTL21D OS=Homo sapiens GN=METTL21D PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.0 0.0011 0.63 32 77 .. 68 112 .. 47 141 .. 0.74 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.0011 CSEEEEET-TTSHHHHHHHHHTTC.EEEEEESB.HHHHHHHHHHHHH CS MTS 32 sgkvlDlGcGaGvlgaalakespeaevtlvdvd.arAlesakenlea 77 +++vl lG+G+G++g+++a ++ +++d + + l + n+++ sp|Q9H867|MT21D_HUMAN 68 RRSVLELGSGTGAVGLMAATLGADV--VVTDLEeLQDLLKMNINMNK 112 578*****************99995..55554303334444444444 PP >> sp|Q9NVM4-2|ANM7_HUMAN Isoform 2 of Protein arginine N-methyltransferase 7 OS=Homo sapiens GN=PRMT7 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.0 0.0014 0.83 28 69 .. 60 101 .. 50 128 .. 0.78 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.0014 HCC.TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHH CS MTS 28 pke.lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAle 69 +++ ++ vlD+G+G+G+l++++ + + +++++ +A+ sp|Q9NVM4-2|ANM7_HUMAN 60 KDRgQKALVLDIGTGTGLLSMMAVTAGAD-FCYAIEENCEAVP 101 554456669************99998888.4888999999985 PP >> tr|H3BRQ9|H3BRQ9_HUMAN Protein arginine N-methyltransferase 7 OS=Homo sapiens GN=PRMT7 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.8 0.0 0.0011 0.65 26 53 .. 58 86 .. 47 102 .. 0.78 Alignments for each domain: == domain 1 score: 11.8 bits; conditional E-value: 0.0011 HCHCC.TCSEEEEET-TTSHHHHHHHHHT CS MTS 26 tlpke.lsgkvlDlGcGaGvlgaalakes 53 ++++ ++ vlD+G+G+G+l++++ + tr|H3BRQ9|H3BRQ9_HUMAN 58 RVKDRgQKALVLDIGTGTGLLSMMAVTAG 86 5555555667************9987665 PP >> sp|O43159|RRP8_HUMAN Ribosomal RNA-processing protein 8 OS=Homo sapiens GN=RRP8 PE=1 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 6.3 0.0 0.054 31 30 85 .. 306 362 .. 297 371 .. 0.83 2 ? 3.6 0.0 0.36 2.1e+02 119 150 .. 372 405 .. 366 418 .. 0.77 Alignments for each domain: == domain 1 score: 6.3 bits; conditional E-value: 0.054 C.TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEE CS MTS 30 e.lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevv 85 + +s v+D+GcG l+ ++ + ++ +d ++a+ le++ ++v v+ sp|O43159|RRP8_HUMAN 306 RpASLVVADFGCGDCRLASSIRNPVHCFDLASLDPRVTVCDMAQVPLEDESVDVAVF 362 4455569**************999999999999999999999999999999997776 PP == domain 2 score: 3.6 bits; conditional E-value: 0.36 HHHHHHHHHHEEEEEEEEE..EEETTSCHHHHHH CS MTS 119 eeliaeAkeaLkegGeLli..Vanrklgyeslle 150 +++++eA+++Lk+gG L + V +r+ ++++ l+ sp|O43159|RRP8_HUMAN 372 RDFLEEANRVLKPGGLLKVaeVSSRFEDVRTFLR 405 689************8876446666666666555 PP >> sp|Q9P272|K1456_HUMAN Putative methyltransferase KIAA1456 OS=Homo sapiens GN=KIAA1456 PE=2 SV=3 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.1 0.1 0.0038 2.2 29 138 .. 41 140 .. 35 157 .. 0.76 Alignments for each domain: == domain 1 score: 10.1 bits; conditional E-value: 0.0038 CC.TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTTSTTS-EEEEEE---STTTCHCHH CS MTS 29 ke.lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasdvleeveekkfdlivsNPPfhagkatel 115 ++ ++D+GcG+G + +k +++++ + +d +e+a++ +v ++ + ++ fd+i+s +h+ + ++ sp|Q9P272|K1456_HUMAN 41 EQkPGSLIADIGCGTG----KYLKVNSQVHTVGCDYCGPLVEIARNR-----GCEAMVCDNLNLPFRDEGFDAIISIGVIHHFSTKQ- 118 443455699******9....578889999999999999999988743.....3334566778888999*************998844. PP HHHHHHHHHHHHHEEEEEEEEEE CS MTS 116 avaeeliaeAkeaLkegGeLliV 138 + i+e +++L +gG+L+i sp|Q9P272|K1456_HUMAN 119 -RRIRAIKEMARVLVPGGQLMIY 140 .4457799999********9984 PP >> tr|B4DWM3|B4DWM3_HUMAN Williams-Beuren syndrome chromosomal region 27 protein OS=Homo sapiens GN=WBSCR27 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.0 0.0015 0.87 22 48 .. 57 84 .. 49 88 .. 0.81 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.0015 HHHHHCHCC.TCSEEEEET-TTSHHHHH CS MTS 22 lLletlpke.lsgkvlDlGcGaGvlgaa 48 L ++lp +s +lD++cG+G+++a+ tr|B4DWM3|B4DWM3_HUMAN 57 CLTQALPGPpHSALILDVACGTGLVAAE 84 56677777788889**********9985 PP >> sp|Q9UBP6|TRMB_HUMAN tRNA (guanine-N(7)-)-methyltransferase OS=Homo sapiens GN=METTL1 PE=1 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 0.0 0.0029 1.7 32 78 .. 77 123 .. 69 220 .. 0.61 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.0029 CSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHT CS MTS 32 sgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenlean 78 + + +D+GcG+G l ++l p++ + +++ + + + ++a sp|Q9UBP6|TRMB_HUMAN 77 QVEFADIGCGYGGLLVELSPLFPDTLILGLEIRVKVSDYVQDRIRAL 123 55689*************99999987777777666555555555544 PP >> sp|Q9H825-2|METL8_HUMAN Isoform 2 of Methyltransferase-like protein 8 OS=Homo sapiens GN=METTL8 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.9 0.1 8.6 5e+03 124 165 .. 10 51 .. 8 52 .. 0.85 2 ? 9.5 0.0 0.0054 3.2 34 91 .. 149 209 .. 141 225 .. 0.78 Alignments for each domain: == domain 1 score: -0.9 bits; conditional E-value: 8.6 HHHHHEEEEEEEEEEEETTSCHHHHHHHHHS--EEEEEESSE CS MTS 124 eAkeaLkegGeLliVanrklgyeslleelfgnvevvaktkkf 165 +A++ ke+ ++ +++++ye+ ++ + ++ + k+k f sp|Q9H825-2|METL8_HUMAN 10 AARKKVKENSAVRVLLEEQVKYEREASKYWDTFYKIHKNKFF 51 688888999999999999999999999999999999888777 PP == domain 2 score: 9.5 bits; conditional E-value: 0.0054 EEEEET-TTSHHH...HHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTT CS MTS 34 kvlDlGcGaGvlg...aalakespeaevtlvdvdarAlesakenleanklevevvasdvle 91 ++l +GcGaG ++ +++spe + ++d A+e+ k + + ++ ++ +dv + sp|Q9H825-2|METL8_HUMAN 149 RILEVGCGAGNSVfpiLNTLENSPESFLYCCDFASGAVELVKSHSSYRATQCFAFVHDVCD 209 699*******65411145567789988***************9999999887777777765 PP >> tr|G3V353|G3V353_HUMAN Methyltransferase-like protein 17, mitochondrial (Fragment) OS=Homo sapiens GN=METTL17 PE=2 S # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 0.0023 1.3 10 75 .. 75 149 .. 70 157 .. 0.77 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.0023 STTTTS--HHHHHHHHHCHCC.......TCSEEEEET-TTSHHHHHHHHHTTC.E..EEEEESBHHHHHHHHHHH CS MTS 10 vFskdklDkGsklLletlpke.......lsgkvlDlGcGaGvlgaalakespeae..vtlvdvdarAlesakenl 75 v+ +++lD G + +++++ + ++++D+G+G+G ++ a+ + + + +vd +a+ l +a++ l tr|G3V353|G3V353_HUMAN 75 VYMAARLDGGFAAVSRAFHEIrarnpafQPQTLMDFGSGTGSVTWAAHSIWGQSLreYMCVDRSAAMLVLAEKLL 149 788888888888888888877444555444569***********9999988775334899999999888887755 PP >> tr|E7ETE0|E7ETE0_HUMAN Methyltransferase-like protein 8 OS=Homo sapiens GN=METTL8 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.0 0.0 0.0082 4.8 34 92 .. 199 260 .. 191 307 .. 0.76 Alignments for each domain: == domain 1 score: 9.0 bits; conditional E-value: 0.0082 EEEEET-TTSHHH...HHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTT CS MTS 34 kvlDlGcGaGvlg...aalakespeaevtlvdvdarAlesakenleanklevevvasdvlee 92 ++l +GcGaG ++ +++spe + ++d A+e+ k + + ++ ++ +dv ++ tr|E7ETE0|E7ETE0_HUMAN 199 RILEVGCGAGNSVfpiLNTLENSPESFLYCCDFASGAVELVKSHSSYRATQCFAFVHDVCDD 260 699*******65411145567789988***************99999999977777776654 PP >> sp|Q9H825|METL8_HUMAN Methyltransferase-like protein 8 OS=Homo sapiens GN=METTL8 PE=2 SV=2 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -0.8 0.1 8.2 4.8e+03 123 165 .. 59 101 .. 44 102 .. 0.85 2 ? 9.0 0.0 0.0077 4.5 34 91 .. 199 259 .. 191 275 .. 0.78 Alignments for each domain: == domain 1 score: -0.8 bits; conditional E-value: 8.2 HHHHHHEEEEEEEEEEEETTSCHHHHHHHHHS--EEEEEESSE CS MTS 123 aeAkeaLkegGeLliVanrklgyeslleelfgnvevvaktkkf 165 a+A++ ke+ ++ +++++ye+ ++ + ++ + k+k f sp|Q9H825|METL8_HUMAN 59 AAARKKVKENSAVRVLLEEQVKYEREASKYWDTFYKIHKNKFF 101 5688889999999999999999999999999999999888776 PP == domain 2 score: 9.0 bits; conditional E-value: 0.0077 EEEEET-TTSHHH...HHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTT CS MTS 34 kvlDlGcGaGvlg...aalakespeaevtlvdvdarAlesakenleanklevevvasdvle 91 ++l +GcGaG ++ +++spe + ++d A+e+ k + + ++ ++ +dv + sp|Q9H825|METL8_HUMAN 199 RILEVGCGAGNSVfpiLNTLENSPESFLYCCDFASGAVELVKSHSSYRATQCFAFVHDVCD 259 699*******65411145567789988***************9999999887777777765 PP >> tr|F8WD87|F8WD87_HUMAN Uncharacterized methyltransferase WBSCR22 OS=Homo sapiens GN=WBSCR22 PE=2 SV=1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.0 0.0026 1.5 24 52 .. 46 74 .. 29 85 .. 0.80 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.0026 HHHCHCCTCSEEEEET-TTSHHHHHHHHH CS MTS 24 letlpkelsgkvlDlGcGaGvlgaalake 52 l +lp+++ +lD+GcG+G+ g l +e tr|F8WD87|F8WD87_HUMAN 46 LLYLPENKPCYLLDIGCGTGLSGSYLSDE 74 567888877789********999888765 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (169 nodes) Target sequences: 88473 (35070517 residues searched) Passed MSV filter: 1899 (0.0214642); expected 1769.5 (0.02) Passed bias filter: 1710 (0.0193279); expected 1769.5 (0.02) Passed Vit filter: 327 (0.00369604); expected 88.5 (0.001) Passed Fwd filter: 151 (0.00170674); expected 0.9 (1e-05) Initial search space (Z): 88473 [actual number of targets] Domain search space (domZ): 151 [number of targets reported over threshold] # CPU time: 0.59u 0.03s 00:00:00.62 Elapsed: 00:00:00.24 # Mc/sec: 24695.49 // [ok]