# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/MTS.hmm.txt
# target sequence database:        proteomes/Petromyzon_marinus.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       MTS  [M=169]
Accession:   PF05175.13
Description: Methyltransferase small domain
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
    1.3e-14   53.7   0.0    2.6e-06   26.7   0.0    2.8  3  tr|S4R4I3|S4R4I3_PETMA  Phosphoethanolamine methyltransferase
    1.1e-12   47.5   0.2    2.7e-12   46.2   0.2    1.6  1  tr|S4RMF5|S4RMF5_PETMA  HemK methyltransferase family member 
    9.2e-12   44.4   0.0    1.2e-11   44.0   0.0    1.2  1  tr|S4RXG9|S4RXG9_PETMA  Methyltransferase like 5 OS=Petromyzo
    1.5e-10   40.5   0.1    0.00013   21.2   0.0    2.9  3  tr|S4RMG0|S4RMG0_PETMA  Phosphoethanolamine methyltransferase
    1.6e-07   30.6   0.0    1.1e-06   27.9   0.0    2.0  2  tr|S4RFW7|S4RFW7_PETMA  Coactivator-associated arginine methy
    3.2e-07   29.6   0.0    4.7e-07   29.1   0.0    1.2  1  tr|S4RQZ8|S4RQZ8_PETMA  THUMP domain containing 2 OS=Petromyz
    1.3e-06   27.7   0.0    2.4e-06   26.8   0.0    1.4  1  tr|S4RS03|S4RS03_PETMA  Methyltransferase like 16 OS=Petromyz
    9.9e-06   24.8   0.0    1.8e-05   24.0   0.0    1.4  1  tr|S4R684|S4R684_PETMA  EEF1A lysine methyltransferase 2 OS=P
    1.5e-05   24.2   0.0    2.4e-05   23.5   0.0    1.3  1  tr|S4RW71|S4RW71_PETMA  Protein arginine methyltransferase 2 
    7.1e-05   22.0   0.0    0.00021   20.5   0.0    1.8  2  tr|S4RWE3|S4RWE3_PETMA  Acetylserotonin O-methyltransferase O
    0.00027   20.1   0.0      0.018   14.2   0.0    2.1  2  tr|S4RFT9|S4RFT9_PETMA  Zgc:162396 OS=Petromyzon marinus OX=7
    0.00042   19.5   0.0    0.00065   18.9   0.0    1.3  1  tr|S4RXY4|S4RXY4_PETMA  Methyltransferase-like protein OS=Pet
    0.00098   18.3   0.0     0.0017   17.6   0.0    1.4  1  tr|S4RRK5|S4RRK5_PETMA  Methyltransferase-like protein OS=Pet
     0.0017   17.5   0.0     0.0037   16.4   0.0    1.5  2  tr|S4RW29|S4RW29_PETMA  Protein-L-isoaspartate O-methyltransf
     0.0018   17.4   0.1     0.0028   16.8   0.1    1.3  1  tr|S4RPG9|S4RPG9_PETMA  Protein arginine methyltransferase 1 
     0.0033   16.6   0.1     0.0052   16.0   0.1    1.4  1  tr|S4R827|S4R827_PETMA  Protein-L-isoaspartate (D-aspartate) 
     0.0059   15.8   0.3      0.049   12.8   0.0    2.2  3  tr|S4RIF9|S4RIF9_PETMA  Calmodulin-lysine N-methyltransferase
     0.0071   15.5   0.0       0.01   15.0   0.0    1.2  1  tr|S4RY85|S4RY85_PETMA  Electron transfer flavoprotein subuni
     0.0098   15.1   0.0      0.017   14.3   0.0    1.3  1  tr|S4RQC2|S4RQC2_PETMA  Citrate synthase lysine methyltransfe
  ------ inclusion threshold ------
      0.011   14.9   0.0      0.038   13.1   0.0    1.8  2  tr|S4RA41|S4RA41_PETMA  Acetylserotonin O-methyltransferase O
      0.014   14.5   0.1      0.019   14.1   0.1    1.2  1  tr|S4RNP9|S4RNP9_PETMA  Methyltransferase like 21A OS=Petromy
      0.026   13.7   0.0      0.058   12.5   0.0    1.5  1  tr|S4R4T4|S4R4T4_PETMA  Methyltransferase like 22 OS=Petromyz
       0.04   13.1   0.0      0.048   12.8   0.0    1.2  1  tr|S4RXH9|S4RXH9_PETMA  Uncharacterized protein OS=Petromyzon
      0.066   12.4   0.0       0.14   11.3   0.0    1.5  1  tr|S4RMN3|S4RMN3_PETMA  tRNA (guanine(26)-N(2))-dimethyltrans
       0.15   11.2   0.0       0.27   10.4   0.0    1.3  1  tr|S4RR13|S4RR13_PETMA  tRNA methyltransferase 44 homolog OS=


Domain annotation for each sequence (and alignments):
>> tr|S4R4I3|S4R4I3_PETMA  Phosphoethanolamine methyltransferase OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.7   0.0   4.7e-09   2.6e-06      24     136 ..      43     150 ..      40     160 .. 0.87
   2 ?   -2.4   0.1       4.1   2.2e+03     106     165 ..     169     197 ..     165     217 .. 0.56
   3 !   23.6   0.0   4.2e-08   2.3e-05      20     137 ..     272     385 ..     259     403 .. 0.79

  Alignments for each domain:
  == domain 1  score: 26.7 bits;  conditional E-value: 4.7e-09
                             HHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTT.TSTTS-EEEEEE---STT CS
                     MTS  24 letlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasdvle.eveekkfdlivsNPPfha 109
                             l+ lp+  + kvl lG+G+G  + +lak+  +  vt+vd     l+  ++ l++ ++++++++ dv++ +++e++fd+i sN  f  
  tr|S4R4I3|S4R4I3_PETMA  43 LSLLPNIDDAKVLELGAGIGRFTGHLAKQARH--VTAVDFMQTFLDK-NRELNSDHVNIKFLQADVTQlQFPENSFDVIFSNWLFMY 126
                             67788888999*****************8887..99**998887776.5568899999********9856779*********99998 PP

                             TCHCHHHHHHHHHHHHHHHEEEEEEEE CS
                     MTS 110 gkatelavaeeliaeAkeaLkegGeLl 136
                              ++   +   +l+++  + L++gG+L+
  tr|S4R4I3|S4R4I3_PETMA 127 LTD---EELLRLVNSMLRWLRPGGHLF 150
                             777...678899999999999999998 PP

  == domain 2  score: -2.4 bits;  conditional E-value: 4.1
                             -STTTCHCHHHHHHHHHHHHHHHEEEEEEEEEEEETTSCHHHHHHHHHS--EEEEEESSE CS
                     MTS 106 PfhagkatelavaeeliaeAkeaLkegGeLliVanrklgyeslleelfgnvevvaktkkf 165
                              + ++ a                               +y++++++ f++ +  +k  +f
  tr|S4R4I3|S4R4I3_PETMA 169 TIYRKPA-------------------------------QYNHIMQAGFQQAKGNEKSFGF 197
                             4444444...............................4555555555554444444333 PP

  == domain 3  score: 23.6 bits;  conditional E-value: 4.2e-08
                             HHHHHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTT.TSTTS-EEEEEE- CS
                     MTS  20 sklLletlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdvle.eveekkfdlivsN 104
                             +k +++ l+ ++ +kvlD+GcG+G     +ak+ +  +v  +d + + +e+a e +++     v++  sd+++ +++e++fd++ s 
  tr|S4R4I3|S4R4I3_PETMA 272 TKEFVSLLDLQAGQKVLDVGCGIGGGNFYMAKAFKV-DVLGMDLSSNMVEIAMERATEDSTLlVQFEISDATKrDFPEESFDVVYSR 357
                             666789999999*************99999997665.899***********988877766656*******98636889*****9874 PP

                             --STTTCHCHHHHHHHHHHHHHHHEEEEEEEEE CS
                     MTS 105 PPfhagkatelavaeeliaeAkeaLkegGeLli 137
                               + +  +       +l++   + Lk+gG+Lli
  tr|S4R4I3|S4R4I3_PETMA 358 DTILHIAD-----KFALFKRFYRWLKPGGKLLI 385
                             44333222.....34556666777777777766 PP

>> tr|S4RMF5|S4RMF5_PETMA  HemK methyltransferase family member 1 OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   46.2   0.2     5e-15   2.7e-12      34     108 ..      61     147 ..      36     159 .. 0.79

  Alignments for each domain:
  == domain 1  score: 46.2 bits;  conditional E-value: 5e-15
                             EEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTTTSTT..........S-EEEEEE---ST CS
                     MTS  34 kvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvleevee..........kkfdlivsNPPfh 108
                             +vlD+GcG G++++a++++sp a+ ++vd++a A+++a+en+e+  l+  ++vv+ d+++              + fd++vsNPP+ 
  tr|S4RMF5|S4RMF5_PETMA  61 RVLDIGCGSGAISLAILSASPLASCVAVDKSADAVALARENAEDLSLQdrCSVVQLDITAVGRAahateavgalGPFDVLVSNPPYV 147
                             59*********************************************999888888876532210011112222579********75 PP

>> tr|S4RXG9|S4RXG9_PETMA  Methyltransferase like 5 OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   44.0   0.0   2.3e-14   1.2e-11      18     114 ..      35     138 ..      30     177 .. 0.85

  Alignments for each domain:
  == domain 1  score: 44.0 bits;  conditional E-value: 2.3e-14
                             HHHHHHHHHCHCC...TCSE.EEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTST...TS CS
                     MTS  18 kGsklLletlpke...lsgk.vlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdvleeve...ek 96 
                             ++++ +l+t++++   l+gk v DlGcG Gvl++ +a     +  + +dvd +Ale + +n+ + ++  v+vv+sdv +  +    k
  tr|S4RXG9|S4RXG9_PETMA  35 IAAACMLHTIHTRyddLEGKlVGDLGCGCGVLSIGAAMLGAGL-CVGFDVDEEALETCLHNVDEFDVGvVDVVQSDVCALHQprwRK 120
                             56778888888888784444378************99988885.8899******************999*******98766533469 PP

                             -EEEEEE---STTTCHCH CS
                     MTS  97 kfdlivsNPPfhagkate 114
                              f ++v+NPPf +++++ 
  tr|S4RXG9|S4RXG9_PETMA 121 AFHTVVMNPPFGTKQNKG 138
                             9**********8887644 PP

>> tr|S4RMG0|S4RMG0_PETMA  Phosphoethanolamine methyltransferase OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.7   0.0   1.2e-05    0.0063      24     104 ..      40     118 ..      38     138 .. 0.81
   2 !   21.2   0.0   2.3e-07   0.00013      20     137 ..     270     383 ..     251     386 .. 0.76
   3 ?   -1.5   0.0       2.2   1.2e+03      72     102 ..     440     466 ..     422     467 .. 0.72

  Alignments for each domain:
  == domain 1  score: 15.7 bits;  conditional E-value: 1.2e-05
                             HHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTT.TSTTS-EEEEEE- CS
                     MTS  24 letlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvle.eveekkfdlivsN 104
                             l+ lp+    ++l lG+G+G  + +lak  ++  vt+vd   + ++   +n e+n+++  +++++ dv++ +++ ++fd+i sN
  tr|S4RMG0|S4RMG0_PETMA  40 LSLLPNLDGTDILELGAGIGRFTGHLAKIANH--VTAVDFMENFIA---KNKEDNGHRgnLTFLQADVTQlDFPANSFDVIFSN 118
                             56677777789*****************9988..888888887665...55556665555999****99857889********9 PP

  == domain 2  score: 21.2 bits;  conditional E-value: 2.3e-07
                             HHHHHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTST.TS-EEEEEE- CS
                     MTS  20 sklLletlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdvleeve.ekkfdlivsN 104
                             ++ +l  l  ++ +kvlD+GcG+G     + k +  +ev  vd + + +++a e + ++++  v++  sd+++ v  e++fd++ s 
  tr|S4RMG0|S4RMG0_PETMA 270 TEEFLAMLGLRQGQKVLDVGCGIGGGDFLMSKLY-GVEVLGVDLSSNMVAIAMERAVEEDAPlVQFEISDATKRVFpENSFDVVYSR 355
                             55566777777899**********9666666655.569************9999888888888**********9875899***9875 PP

                             --STTTCHCHHHHHHHHHHHHHHHEEEEEEEEE CS
                     MTS 105 PPfhagkatelavaeeliaeAkeaLkegGeLli 137
                               + +  +       +l+++  + Lk+gG+Lli
  tr|S4RMG0|S4RMG0_PETMA 356 DTILHIAD-----KVALFKSFYAWLKPGGKLLI 383
                             44333222.....34566666677777777765 PP

  == domain 3  score: -1.5 bits;  conditional E-value: 2.2
                             HHHHHHTTGCEEEEE-STTTTSTTS-EEEEE CS
                     MTS  72 kenleanklevevvasdvleeveekkfdliv 102
                             k+ +    +++e+v+ + ++e++++++d+iv
  tr|S4RMG0|S4RMG0_PETMA 440 KQEV----ARTELVKDEFVKEFSQDDYDYIV 466
                             3333....33678999999999999999998 PP

>> tr|S4RFW7|S4RFW7_PETMA  Coactivator-associated arginine methyltransferase 1 OS=Petromyzon marinus OX=7757 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.9   0.0     2e-09   1.1e-06      31     136 ..     160     262 ..     146     270 .. 0.77
   2 ?   -0.1   0.0      0.84   4.6e+02     120     155 ..     401     434 ..     387     441 .. 0.79

  Alignments for each domain:
  == domain 1  score: 27.9 bits;  conditional E-value: 2e-09
                             TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTTTSTTS-EEEEEE---STTTCHCHH CS
                     MTS  31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvleeveekkfdlivsNPPfhagkatel 115
                             +++ vlD+GcG G+l+  + ++  + +v +v+++ +A + a+  +++n+l+  + v+   v +   ++k+d+i+s P    g    +
  tr|S4RFW7|S4RFW7_PETMA 160 RDKIVLDVGCGSGILSFFAVQAGAR-KVYAVEASSMA-QHAEVLVRSNNLQdrIVVIPGKVEDVSIPDKVDVIISEP---MGYMLFN 241
                             66679************99998877.8*********9.56777788888887888888888877779********99...3444444 PP

                             HHHHHHHHHHHHHEEEEEEEE CS
                     MTS 116 avaeeliaeAkeaLkegGeLl 136
                             + + e   +Ak+ Lk++G+++
  tr|S4RFW7|S4RFW7_PETMA 242 ERMLESYLHAKKWLKPNGNMF 262
                             455555567888888888875 PP

  == domain 2  score: -0.1 bits;  conditional E-value: 0.84
                             HHHHHHHHHEEEEEEEEEEEETTSCHHHHHHHHHS- CS
                     MTS 120 eliaeAkeaLkegGeLliVanrklgyeslleelfgn 155
                              l+++A + L  +G+ +++an+ + y+  l +++ +
  tr|S4RFW7|S4RFW7_PETMA 401 PLFTKAGDTL--SGTVVMIANKRQSYDINLVAVVDQ 434
                             5677777777..59************9888877766 PP

>> tr|S4RQZ8|S4RQZ8_PETMA  THUMP domain containing 2 OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   29.1   0.0   8.6e-10   4.7e-07      33     138 ..     269     380 ..     258     382 .] 0.85

  Alignments for each domain:
  == domain 1  score: 29.1 bits;  conditional E-value: 8.6e-10
                             SEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTT.TSTTS-EEEEEE---STTTC...HC CS
                     MTS  33 gkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvle.eveekkfdlivsNPPfhagk...at 113
                               v+D  cG+G l +++a ++++++   +dvda+ l+ aken++  +l+  + +++ +v++  ++   +d+i++  Pf ++    ++
  tr|S4RQZ8|S4RQZ8_PETMA 269 AVVMDPMCGMGTLLLEAAMAWKTVRCLGTDVDAQQLAHAKENIHFAELDhrIGLLQASVTAlPIPCSAIDVIICDIPFGQKYssdEE 355
                             468999******************************************98877788777763567899**********998722244 PP

                             HHHHHHHHHHHHHHHEEEEEEEEEE CS
                     MTS 114 elavaeeliaeAkeaLkegGeLliV 138
                              ++++ ++++e  ++L+ gG++++ 
  tr|S4RQZ8|S4RQZ8_PETMA 356 MKHLMPKILQEMMRVLRVGGNIVLL 380
                             45677799************99875 PP

>> tr|S4RS03|S4RS03_PETMA  Methyltransferase like 16 OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.8   0.0   4.4e-09   2.4e-06      24     118 ..      68     173 ..      64     205 .. 0.82

  Alignments for each domain:
  == domain 1  score: 26.8 bits;  conditional E-value: 4.4e-09
                             HHHCHCC..TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.........EEEEE-STTTTSTTS-EE CS
                     MTS  24 letlpke..lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.........vevvasdvleeveekkfd 99 
                              + l+ +  +s + +D+G+Ga  +   l +  +  +  +++vd    + a++n+++n+l+          +++  ++l+e +e  +d
  tr|S4RS03|S4RS03_PETMA  68 GSSLSRDpeKSVHGIDIGTGASCIYPLLGATMNGWHFLATEVDNVCFTYATQNVARNGLQglvrvmkvpQKTLLVEALNEDPELAYD 154
                             55666664456678**********************************************9977744444444455666666789** PP

                             EEEE---STTTCHCHHHHH CS
                     MTS 100 livsNPPfhagkatelava 118
                             + v+NPPf a++++ + v 
  tr|S4RS03|S4RS03_PETMA 155 FCVCNPPFFANQQEAYGVN 173
                             **********999887665 PP

>> tr|S4R684|S4R684_PETMA  EEF1A lysine methyltransferase 2 OS=Petromyzon marinus OX=7757 GN=EEF1AKMT2 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.0   0.0   3.3e-08   1.8e-05      31      89 ..      78     136 ..      67     145 .. 0.83

  Alignments for each domain:
  == domain 1  score: 24.0 bits;  conditional E-value: 3.3e-08
                             TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-ST CS
                     MTS  31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdv 89 
                             ++ +vlD+G+G+Gvl ++lak   + ++t +d +a+A+++a+  ++++++  + + + d 
  tr|S4R684|S4R684_PETMA  78 KDSSVLDIGTGNGVLLLELAKVGFT-RLTGIDYSAAAVRLAQSIASEQGHPhIVFQEVDF 136
                             5678*****************7766.8***************999988877566666665 PP

>> tr|S4RW71|S4RW71_PETMA  Protein arginine methyltransferase 2 OS=Petromyzon marinus OX=7757 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   23.5   0.0   4.5e-08   2.4e-05      32     103 ..     135     207 ..     124     238 .. 0.85

  Alignments for each domain:
  == domain 1  score: 23.5 bits;  conditional E-value: 4.5e-08
                             CSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTTTSTTS-EEEEEE CS
                     MTS  32 sgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvleeveekkfdlivs 103
                              + vlD+GcG G++++ +ak+ +  +v +v+++  A +++++ ++ n+++  v+v++  v +   ++++d++vs
  tr|S4RW71|S4RW71_PETMA 135 GKAVLDVGCGSGIISMLCAKHAQPSRVYAVEASELA-RLTEQVVRCNGMKdtVRVLQGRVEDVELPGSVDCLVS 207
                             567******************************999.7899999999999877777766655555677777775 PP

>> tr|S4RWE3|S4RWE3_PETMA  Acetylserotonin O-methyltransferase OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -2.5   0.0       4.5   2.4e+03      33      50 ..      67      84 ..      53     104 .. 0.75
   2 !   20.5   0.0   3.8e-07   0.00021      24      78 ..     178     231 ..     174     257 .. 0.78

  Alignments for each domain:
  == domain 1  score: -2.5 bits;  conditional E-value: 4.5
                            SEEEEET-TTSHHHHHHH CS
                     MTS 33 gkvlDlGcGaGvlgaala 50
                            ++++D + G G+l +++ 
  tr|S4RWE3|S4RWE3_PETMA 67 ERLVDACVGLGLLRVSIH 84
                            467888888888877654 PP

  == domain 2  score: 20.5 bits;  conditional E-value: 3.8e-07
                             HHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHT CS
                     MTS  24 letlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenlean 78 
                             l++++ +  ++v D+G G+Gvl+ ++a+++p+a+vtl+d   + le+a++ + ++
  tr|S4RWE3|S4RWE3_PETMA 178 LNAFDLSSFKDVCDVGGGTGVLAQQFARMYPDARVTLFDLP-EVLEVAQKHFLSS 231
                             56677777889****************************85.4577777666554 PP

>> tr|S4RFT9|S4RFT9_PETMA  Zgc:162396 OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.2   0.0   3.3e-05     0.018       9      80 ..      16      88 ..      11     102 .. 0.79
   2 ?    4.0   0.0     0.047        25     119     137 ..     120     138 ..     109     160 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.2 bits;  conditional E-value: 3.3e-05
                            TSTTTTS--HHHHHHHHHCHCCTCSE...EEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTG CS
                     MTS  9 gvFskdklDkGsklLletlpkelsgk...vlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankl 80
                            + ++ +  D++ + +++++ +++ g    ++D+GcG G  +  l + +p+  v+ vdv+ + ++ a++  +++++
  tr|S4RFT9|S4RFT9_PETMA 16 NLYHPGVPDAAFRAIMDYVRAKTGGVpslAVDVGCGSGQCTRLLSRCCPR--VVGVDVSEAMIREATRVNRTENI 88
                            566777788899999999999844434449********************..999***99999887776655555 PP

  == domain 2  score: 4.0 bits;  conditional E-value: 0.047
                             HHHHHHHHHHEEEEEEEEE CS
                     MTS 119 eeliaeAkeaLkegGeLli 137
                              ++++eA+++L++gG L +
  tr|S4RFT9|S4RFT9_PETMA 120 PDFVREAARVLQPGGCLAV 138
                             579************9986 PP

>> tr|S4RXY4|S4RXY4_PETMA  Methyltransferase-like protein OS=Petromyzon marinus OX=7757 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.9   0.0   1.2e-06   0.00065      34     101 ..      95     167 ..      84     198 .. 0.85

  Alignments for each domain:
  == domain 1  score: 18.9 bits;  conditional E-value: 1.2e-06
                             EEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.....EEEEE-STTTTSTTS-EEEE CS
                     MTS  34 kvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.....vevvasdvleeveekkfdli 101
                              vl  GcG+G     l++e p++ v ++d + rA+++ k n   +k +     +++++++++e+v+e+ +d++
  tr|S4RXY4|S4RXY4_PETMA  95 VVLEAGCGVGNCLFPLLEEDPNIFVYACDFSPRAVDFVKSNPLYSKERclafqCDLTQNSLVENVPEGTVDAV 167
                             48999************************************87776664445577777777888888888876 PP

>> tr|S4RRK5|S4RRK5_PETMA  Methyltransferase-like protein OS=Petromyzon marinus OX=7757 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   17.6   0.0   3.1e-06    0.0017      33     134 ..     183     288 ..     145     293 .. 0.76

  Alignments for each domain:
  == domain 1  score: 17.6 bits;  conditional E-value: 3.1e-06
                             SEEEEET-TTSHHHHHHHHHT..TC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTTST.....TS-EEEEEE---STTTCH CS
                     MTS  33 gkvlDlGcGaGvlgaalakes..peaevtlvdvdarAlesakenleanklevevvasdvleeve.....ekkfdlivsNPPfhagka 112
                              ++l +GcGaG     +++ +  p++ v  +d +  A+e+ k   +  + +++++ +d+ +e++     e+++d+++s   +   +a
  tr|S4RRK5|S4RRK5_PETMA 183 FRILEIGCGAGNTIFPILQTNndPDVFVYGCDFSQSAVELVKSHQNYDASRCHAFVHDLCDETStfpfpEESLDIVIS---IFVLSA 266
                             479********8777776665116666999***********9999999999999999998876433344788888887...555555 PP

                             CHHHHHHHHHHHHHHHEEEEEE CS
                     MTS 113 telavaeeliaeAkeaLkegGe 134
                             ++ + +++ ++   + Lk+gG 
  tr|S4RRK5|S4RRK5_PETMA 267 IHPEKVQAAVTRLSRLLKPGGV 288
                             5666666666666666666665 PP

>> tr|S4RW29|S4RW29_PETMA  Protein-L-isoaspartate O-methyltransferase OS=Petromyzon marinus OX=7757 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.4   0.0   6.8e-06    0.0037      21      80 ..      93     151 ..      86     167 .. 0.81
   2 ?   -3.0   0.0       6.4   3.5e+03     118     136 ..     184     203 ..     177     206 .. 0.68

  Alignments for each domain:
  == domain 1  score: 16.4 bits;  conditional E-value: 6.8e-06
                             HHHHHHCHCCTCSEEEEET-TTSHHHHHHHHH.TTC.EEEEEESBHHHHHHHHHHHHHTTG CS
                     MTS  21 klLletlpkelsgkvlDlGcGaGvlgaalake.speaevtlvdvdarAlesakenleankl 80 
                             +lL + l++    ++lD+G+G G+l+a la++  p+ +v  vd   + +  ak n+++ + 
  tr|S4RW29|S4RW29_PETMA  93 ELLQDRLQE--GASALDVGSGSGYLTACLARMiGPRGKVIGVDHIQELVSEAKVNVQRDDP 151
                             455555555..6679***************98357888*****999999999999998765 PP

  == domain 2  score: -3.0 bits;  conditional E-value: 6.4
                             HHHHHHHH.HHHEEEEEEEE CS
                     MTS 118 aeeliaeA.keaLkegGeLl 136
                             a +++ +A  ++Lk+gG+L+
  tr|S4RW29|S4RW29_PETMA 184 AAAIVPHAlLDQLKPGGRLV 203
                             55566666247899999997 PP

>> tr|S4RPG9|S4RPG9_PETMA  Protein arginine methyltransferase 1 OS=Petromyzon marinus OX=7757 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.8   0.1   5.2e-06    0.0028      31     103 ..      68     141 ..      58     172 .. 0.78

  Alignments for each domain:
  == domain 1  score: 16.8 bits;  conditional E-value: 5.2e-06
                             TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTT.TSTTS-EEEEEE CS
                     MTS  31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvle.eveekkfdlivs 103
                             +++ vlD+G+G+G+l + +ak+  + +v  ++ +  A + +++ ++an+l+  +++v+  v e ++  +k+d+i+s
  tr|S4RPG9|S4RPG9_PETMA  68 KDKVVLDVGSGTGILCMFAAKAGAK-KVFGIECSNIA-DYSQQIIKANNLDsvITIVKGKVEEvDLLVDKVDIIIS 141
                             45679*************9998888.78888888777.78888899999998655555555432233588898887 PP

>> tr|S4R827|S4R827_PETMA  Protein-L-isoaspartate (D-aspartate) O-methyltransferase OS=Petromyzon marinus OX=7757 PE=4 S
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   16.0   0.1   9.6e-06    0.0052      26      91 ..      73     147 ..      68     183 .. 0.76

  Alignments for each domain:
  == domain 1  score: 16.0 bits;  conditional E-value: 9.6e-06
                             HCHCC..TCSEEEEET-TTSHHHHHHHHHTTC.E.EEEEESBHHHHHHHHHHHHHTTGC......EEEEE-STTT CS
                     MTS  26 tlpke..lsgkvlDlGcGaGvlgaalakespeae.vtlvdvdarAlesakenleankle......vevvasdvle 91 
                              l+++  +  +vlD+G+G G+l+a +a++  +   v  +d   + ++ a +n+++ +++      v++v  d+ +
  tr|S4R827|S4R827_PETMA  73 ILQDHlfEGASVLDVGSGSGYLTACIARMVGSSGkVFGIDHIQELVDEAIKNVNKDDMSllssgqVTLVVGDGRQ 147
                             44444444667*****************98876559999999999999999999888776555555555555555 PP

>> tr|S4RIF9|S4RIF9_PETMA  Calmodulin-lysine N-methyltransferase OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   12.8   0.0   9.1e-05     0.049      34      93 ..      23      83 ..      11      92 .. 0.84
   2 ?   -1.7   0.0       2.6   1.4e+03     121     139 ..     117     135 ..     109     158 .. 0.69
   3 ?    0.1   0.0      0.71   3.9e+02      57      81 ..     158     182 ..     145     189 .. 0.78

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 9.1e-05
                            EEEEET-TTSHHH.HHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTTS CS
                     MTS 34 kvlDlGcGaGvlg.aalakespeaevtlvdvdarAlesakenleanklevevvasdvleev 93
                            +v  lG G+  l+ +++a  s+  ev l+d + +A++   + le+n  ++ ++a dv++ v
  tr|S4RIF9|S4RIF9_PETMA 23 SVCELGGGMTCLAgLMVAITSEAKEVLLTDGNDKAVKNVSTILERNTSSGLITAADVTSRV 83
                            588999**99996266666666777*******************************99987 PP

  == domain 2  score: -1.7 bits;  conditional E-value: 2.6
                             HHHHHHHHEEEEEEEEEEE CS
                     MTS 121 liaeAkeaLkegGeLliVa 139
                             l+ + ++ L++gG+ l+ a
  tr|S4RIF9|S4RIF9_PETMA 117 LVDTLHRLLRPGGTVLVFA 135
                             5556667788888777655 PP

  == domain 3  score: 0.1 bits;  conditional E-value: 0.71
                             EEEEEESBHHHHHHHHHHHHHTTGC CS
                     MTS  57 evtlvdvdarAlesakenleankle 81 
                             + +++d++  A++sa ++  +n+ +
  tr|S4RIF9|S4RIF9_PETMA 158 KTEAYDQQVWAIHSAVKTEGKNAYD 182
                             4789999*******99999888876 PP

>> tr|S4RY85|S4RY85_PETMA  Electron transfer flavoprotein subunit beta lysine methyltransferase OS=Petromyzon marinus OX
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.0   0.0   1.9e-05      0.01      21      89 ..      55     134 ..      51     142 .. 0.64

  Alignments for each domain:
  == domain 1  score: 15.0 bits;  conditional E-value: 1.9e-05
                             HHHHHHCHCC....TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHH.....HHHHHHHHHHTTGC...EEEEE-ST CS
                     MTS  21 klLletlpke....lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarA.....lesakenleankle...vevvasdv 89 
                             ++L++ l ++    + + vlDlG+G G+ ++a+ak+  ++ v++ d+d  A       +   n+e n+++   ++vv +d+
  tr|S4RY85|S4RY85_PETMA  55 QVLARFLLDQpgvvAGRAVLDLGSGCGAAAIAAAKAGASL-VVANDIDPGArptvaAVAISLNAELNGVRadsLRVVVRDL 134
                             566666555556658889*************999988885.7788887544111002233455555655555555555555 PP

>> tr|S4RQC2|S4RQC2_PETMA  Citrate synthase lysine methyltransferase OS=Petromyzon marinus OX=7757 GN=CSKMT PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   14.3   0.0   3.1e-05     0.017      34      77 ..      85     129 ..      71     141 .. 0.86

  Alignments for each domain:
  == domain 1  score: 14.3 bits;  conditional E-value: 3.1e-05
                             EEEEET-TTSHHHHHHHHHTT.C.EEEEEESBHHHHHHHHHHHHH CS
                     MTS  34 kvlDlGcGaGvlgaalakesp.eaevtlvdvdarAlesakenlea 77 
                             +vlD+GcG+   ga+l ++s   ++v +vd +  A+e+ ++ +++
  tr|S4RQC2|S4RQC2_PETMA  85 HVLDVGCGTSDFGASLYRASRlPVHVSCVDFSPVAVELMERQWRE 129
                             69*************9887652457*************9998875 PP

>> tr|S4RA41|S4RA41_PETMA  Acetylserotonin O-methyltransferase OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -1.4   0.0       2.1   1.1e+03      33      49 ..      71      87 ..      66     103 .. 0.85
   2 ?   13.1   0.0   7.1e-05     0.038      24      64 ..     182     222 ..     177     252 .. 0.80

  Alignments for each domain:
  == domain 1  score: -1.4 bits;  conditional E-value: 2.1
                            SEEEEET-TTSHHHHHH CS
                     MTS 33 gkvlDlGcGaGvlgaal 49
                            g++lD + G+G+l +++
  tr|S4RA41|S4RA41_PETMA 71 GRLLDACVGMGLLNISV 87
                            5789********99876 PP

  == domain 2  score: 13.1 bits;  conditional E-value: 7.1e-05
                             HHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESB CS
                     MTS  24 letlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvd 64 
                             l++++ +  ++v DlG  +G+l+++la+ +p+ +vt++d  
  tr|S4RA41|S4RA41_PETMA 182 LTAFDLSPFKDVYDLGGCTGALALQLAEIHPDSRVTVFDLP 222
                             56666777789**************************9974 PP

>> tr|S4RNP9|S4RNP9_PETMA  Methyltransferase like 21A OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   14.1   0.1   3.6e-05     0.019      24      81 ..      54     112 ..      43     133 .. 0.75

  Alignments for each domain:
  == domain 1  score: 14.1 bits;  conditional E-value: 3.6e-05
                             HHHCHCC....TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC CS
                     MTS  24 letlpke....lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle 81 
                             +++l+      + ++vl lG+G+G++g+++a    +  v ++d  a  l++ +en+ an ++
  tr|S4RNP9|S4RNP9_PETMA  54 ATYLELGavevKGKRVLELGAGTGLVGIVAALLAAS--VSITDR-APVLAFIQENVDANLAA 112
                             444444334447789***************998888..666664.56788888888888765 PP

>> tr|S4R4T4|S4R4T4_PETMA  Methyltransferase like 22 OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.5   0.0   0.00011     0.058      26      80 ..     186     242 ..     173     260 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.5 bits;  conditional E-value: 0.00011
                             HCHCC....TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTG CS
                     MTS  26 tlpke....lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankl 80 
                             +l ++       ++l lG+G+G+ ++++a +  +  v ++dv    l+ +++n++ank+
  tr|S4R4T4|S4R4T4_PETMA 186 YLLQHrrefCGVTALELGAGTGATSIVAATFART--VYCTDVGDDLLDNCQRNVNANKH 242
                             44443333355679**************998887..9********************86 PP

>> tr|S4RXH9|S4RXH9_PETMA  Uncharacterized protein OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.8   0.0   8.8e-05     0.048      34      78 ..      58     101 ..      37     122 .. 0.73

  Alignments for each domain:
  == domain 1  score: 12.8 bits;  conditional E-value: 8.8e-05
                             EEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHT CS
                     MTS  34 kvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenlean 78 
                             +vlDlGcG G   ++  ++s   ++++ d+ a +++ +++ +++ 
  tr|S4RXH9|S4RXH9_PETMA  58 SVLDLGCGKGGDMLKWRRASIG-HLVCADIAATSVDQCRQRYNDM 101
                             49********655555555444.6************999988765 PP

>> tr|S4RMN3|S4RMN3_PETMA  tRNA (guanine(26)-N(2))-dimethyltransferase OS=Petromyzon marinus OX=7757 PE=3 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.0   0.00025      0.14      35      92 ..     201     259 ..     187     267 .. 0.81

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00025
                             EEEET-TTSHHHHHHHHHTTC.E.EEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTT CS
                     MTS  35 vlDlGcGaGvlgaalakespeae.vtlvdvdarAlesakenleanklevevvasdvlee 92 
                              lD    +G++g++ ak+  ++  vt+ dv+ +++++ +en++ n++ v+  + d  e 
  tr|S4RMN3|S4RMN3_PETMA 201 CLDAFGATGIMGLQWAKHLGNTVrVTINDVSEASVRMMEENCRLNGMTVTESWPDSDEG 259
                             56655568*****99999877655***********************998888887665 PP

>> tr|S4RR13|S4RR13_PETMA  tRNA methyltransferase 44 homolog OS=Petromyzon marinus OX=7757 PE=4 SV=1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0    0.0005      0.27       7      52 ..     236     287 ..     233     297 .. 0.70

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.0005
                             ETTSTTTTS--HHHHHHHHHCHCC......TCSEEEEET-TTSHHHHHHHHH CS
                     MTS   7 lpgvFskdklDkGsklLletlpke......lsgkvlDlGcGaGvlgaalake 52 
                             +p  F ++ + ++s lL+   +++       +++ +DlGcG+G+l   la+e
  tr|S4RR13|S4RR13_PETMA 236 DPEKFVYEDVAIASYLLVLWEEERaergleGRQSFVDLGCGNGLLVHILASE 287
                             55667777777777777755555445554444569**********9988876 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (169 nodes)
Target sequences:                        13539  (5048892 residues searched)
Passed MSV filter:                       297  (0.0219366); expected 270.8 (0.02)
Passed bias filter:                      270  (0.0199424); expected 270.8 (0.02)
Passed Vit filter:                        61  (0.0045055); expected 13.5 (0.001)
Passed Fwd filter:                        25  (0.00184652); expected 0.1 (1e-05)
Initial search space (Z):              13539  [actual number of targets]
Domain search space  (domZ):              25  [number of targets reported over threshold]
# CPU time: 0.10u 0.00s 00:00:00.10 Elapsed: 00:00:00.04
# Mc/sec: 21331.57
//
[ok]