# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/MTS.hmm.txt # target sequence database: proteomes/Tetrahymena_thermophila.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: MTS [M=169] Accession: PF05175.13 Description: Methyltransferase small domain Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 8.6e-13 48.8 0.0 5.2e-12 46.2 0.0 2.0 2 tr|W7XCF3|W7XCF3_TETTS HemK methyltransferase family protein 8.6e-10 39.0 0.1 1.7e-06 28.3 0.0 2.1 2 tr|Q23EX7|Q23EX7_TETTS Methyltransferase small domain protei 2.4e-08 34.3 0.1 5.6e-08 33.1 0.1 1.6 1 tr|Q22SV4|Q22SV4_TETTS Ribosomal protein L11 methyltransfera 5.6e-06 26.6 0.2 1.1e-05 25.7 0.2 1.4 1 tr|I7MKV3|I7MKV3_TETTS Arginine N-methyltransferase OS=Tetra 5.6e-06 26.6 0.0 8.8e-06 25.9 0.0 1.4 1 tr|Q24D55|Q24D55_TETTS Ribosomal protein L11 methyltransfera 9.5e-06 25.8 0.0 1.8e-05 24.9 0.0 1.4 1 tr|Q239D4|Q239D4_TETTS Cyclopropane-fatty-acyl-phospholipid 1e-05 25.8 0.0 2.1e-05 24.7 0.0 1.5 1 tr|I7M361|I7M361_TETTS Methyltransferase-like protein OS=Tet 1.2e-05 25.5 0.0 2.3e-05 24.6 0.0 1.5 1 tr|I7MK94|I7MK94_TETTS AdoMet-dependent proline di-methyltra 2.4e-05 24.6 0.0 5.5e-05 23.4 0.0 1.6 1 tr|Q231G1|Q231G1_TETTS U6 small nuclear RNA (adenine-(43)-N( 2.6e-05 24.4 0.0 0.00012 22.3 0.0 2.1 1 tr|Q22MG6|Q22MG6_TETTS RNA cap guanine-N2 methyltransferase 4.1e-05 23.8 0.0 6.6e-05 23.1 0.0 1.3 1 tr|Q24E29|Q24E29_TETTS UbiE/COQ5 family methyltransferase OS 4.4e-05 23.7 0.0 7.4e-05 22.9 0.0 1.4 1 tr|Q22RB9|Q22RB9_TETTS Methyltransferase domain protein OS=T 7.7e-05 22.9 0.0 0.00014 22.0 0.0 1.3 1 tr|Q22BT0|Q22BT0_TETTS RNA cap guanine-N2 methyltransferase 0.00027 21.1 0.0 0.0007 19.8 0.0 1.7 1 tr|I7MGH3|I7MGH3_TETTS RNA cap guanine-N2 methyltransferase 0.00058 20.0 0.0 0.0011 19.1 0.0 1.4 1 tr|I7MAE9|I7MAE9_TETTS UbiE/COQ5 family methyltransferase OS 0.00069 19.8 0.0 0.0012 19.1 0.0 1.4 1 tr|I7M6M7|I7M6M7_TETTS Methyltransferase domain protein OS=T 0.00072 19.7 0.0 0.0016 18.6 0.0 1.6 1 tr|Q24GH8|Q24GH8_TETTS rRNA adenine N(6)-methyltransferase O 0.00079 19.6 0.3 0.0033 17.6 0.0 2.0 2 tr|I7M457|I7M457_TETTS NOL1/NOP2/sun family protein OS=Tetra 0.00081 19.6 0.0 0.003 17.7 0.0 1.8 2 tr|W7X0Z1|W7X0Z1_TETTS UbiE/COQ5 methyltransferase, putative 0.00082 19.5 0.0 0.002 18.3 0.0 1.7 1 tr|Q235D9|Q235D9_TETTS Ubiquinone biosynthesis O-methyltrans 0.0011 19.2 0.0 0.0037 17.4 0.0 1.8 2 tr|I7LTA0|I7LTA0_TETTS Methyltransferase domain protein OS=T 0.0015 18.7 0.0 0.0054 16.9 0.0 1.8 1 tr|Q23MB9|Q23MB9_TETTS tRNA (guanine-N(7)-)-methyltransferas 0.0019 18.3 0.0 0.004 17.3 0.0 1.4 1 tr|I7M9J8|I7M9J8_TETTS NOL1/NOP2/Sun family protein OS=Tetra 0.0031 17.6 0.1 0.0084 16.2 0.0 1.7 1 tr|I7M1S8|I7M1S8_TETTS tRNA (Uracil-5)-methyltransferase OS= 0.0036 17.4 0.1 0.0056 16.8 0.1 1.3 1 tr|Q24FF7|Q24FF7_TETTS Methyltransferase OS=Tetrahymena ther 0.0036 17.4 0.0 0.0042 17.2 0.0 1.1 1 tr|Q24D56|Q24D56_TETTS UbiE/COQ5 methyltransferase, putative 0.005 17.0 0.0 0.0099 16.0 0.0 1.7 1 tr|I7M1Y0|I7M1Y0_TETTS Protein-L-isoaspartate O-methyltransf 0.0066 16.6 0.0 0.015 15.5 0.0 1.5 1 tr|W7XD08|W7XD08_TETTS tRNA (guanine(37)-N1)-methyltransfera 0.007 16.5 0.0 0.038 14.1 0.0 2.4 2 tr|Q236L4|Q236L4_TETTS L-isoaspartate O-methyltransferase OS 0.0075 16.4 0.3 0.011 15.8 0.3 1.4 1 tr|W7XK56|W7XK56_TETTS Actin-related protein 2/3 complex sub 0.0089 16.2 0.0 0.013 15.7 0.0 1.2 1 tr|I7M351|I7M351_TETTS Kinase domain protein OS=Tetrahymena ------ inclusion threshold ------ 0.01 16.0 0.0 0.028 14.5 0.0 1.7 1 tr|Q245D9|Q245D9_TETTS UbiE/COQ5 family methyltransferase OS 0.018 15.1 0.0 0.045 13.9 0.0 1.7 1 tr|Q23VZ1|Q23VZ1_TETTS UbiE/COQ5 methyltransferase OS=Tetrah 0.02 15.1 0.5 0.078 13.1 0.0 2.2 2 tr|Q23EY2|Q23EY2_TETTS UbiE/COQ5 methyltransferase OS=Tetrah 0.022 14.9 0.0 0.048 13.8 0.0 1.5 1 tr|I7M2L9|I7M2L9_TETTS Methyltransferase OS=Tetrahymena ther 0.033 14.3 0.0 0.071 13.2 0.0 1.5 1 tr|I7M0Y7|I7M0Y7_TETTS Embryo-abundant protein, putative OS= 0.033 14.3 0.0 0.033 14.3 0.0 2.1 1 tr|I7M390|I7M390_TETTS L-isoaspartate O-methyltransferase OS 0.039 14.1 0.3 3.1 7.9 0.0 2.7 2 tr|I7MLB3|I7MLB3_TETTS Translation initiation factor 2B subu 0.065 13.3 0.0 0.18 11.9 0.0 1.8 1 tr|Q24E30|Q24E30_TETTS UbiE/COQ5 methyltransferase OS=Tetrah 0.071 13.2 0.0 0.28 11.3 0.0 1.9 2 tr|W7X1L8|W7X1L8_TETTS AdoMet-dependent proline di-methyltra 0.15 12.1 0.0 1.1 9.3 0.0 2.1 1 tr|W7XIC4|W7XIC4_TETTS UbiE/COQ5 methyltransferase OS=Tetrah 0.16 12.1 0.1 0.25 11.4 0.1 1.4 1 tr|I7MDA5|I7MDA5_TETTS Uncharacterized protein OS=Tetrahymen Domain annotation for each sequence (and alignments): >> tr|W7XCF3|W7XCF3_TETTS HemK methyltransferase family protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 46.2 0.0 8.1e-15 5.2e-12 23 112 .. 106 206 .. 100 217 .. 0.87 2 ? -0.2 0.0 1.5 9.6e+02 115 137 .. 230 252 .. 224 278 .. 0.70 Alignments for each domain: == domain 1 score: 46.2 bits; conditional E-value: 8.1e-15 HHHHCHCC.TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC...........EEEEE-STTTTSTTS- CS MTS 23 Lletlpke.lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle...........vevvasdvleeveekk 97 L+++l+k+ ++ + l +G G+G+++++l+ke+++ + ++d+++ +e+ak+nl+ nk++ ++++++++ ++ + ++ tr|W7XCF3|W7XCF3_TETTS 106 LVNKLSKQkQKCQFLEIGIGTGAISLSLLKENSQFTGIAIDKQKFCIELAKQNLNLNKIDpqrlqlihlecLKFFQNNLNQNPD-QQ 191 6777877766778**********************************************9999999888877788888887777.** PP EEEEEE---STTTCH CS MTS 98 fdlivsNPPfhagka 112 fd+ivsNPP+ ++ tr|W7XCF3|W7XCF3_TETTS 192 FDFIVSNPPYIPTSQ 206 *********865554 PP == domain 2 score: -0.2 bits; conditional E-value: 1.5 HHHHHHHHHHHHHHEEEEEEEEE CS MTS 115 lavaeeliaeAkeaLkegGeLli 137 l+++++++ ++Lk+gG + + tr|W7XCF3|W7XCF3_TETTS 230 LDIVKQILDYGYQILKQGGYIAL 252 57888888888888888886654 PP >> tr|Q23EX7|Q23EX7_TETTS Methyltransferase small domain protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 28.3 0.0 2.6e-09 1.7e-06 20 129 .. 40 164 .. 35 170 .. 0.71 2 ! 8.8 0.0 0.0026 1.7 113 165 .. 187 244 .. 182 248 .. 0.78 Alignments for each domain: == domain 1 score: 28.3 bits; conditional E-value: 2.6e-09 HHHHHHHCHCC......TCSEEEEET-TTSHHHHHH....HHHTTC.E.EEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTST CS MTS 20 sklLletlpke......lsgkvlDlGcGaGvlgaal....akespeae.vtlvdvdarAlesakenleankle.vevvasdvleeve 94 s l++e+l+ e + ++ +G+G G+l +l k++++ + ++d+++ A ++++ +++ +l+ ve+v++dv e + tr|Q23EX7|Q23EX7_TETTS 40 SYLMIEALNLEaensieQGALIVEIGSGSGILINHLvsflDKKNKSSSlAIAIDINYDANILTQKYANHYHLSqVECVNTDVAEGLY 126 5677777776644554333449********98655411115666666645689**********999999999999***999988765 PP ...TS-EEEEEE---STTTCHCHHHHHHHHHHHHHHHE CS MTS 95 ...ekkfdlivsNPPfhagkatelavaeeliaeAkeaL 129 +++ d++++NPP+ +++e a a + + + + L tr|Q23EX7|Q23EX7_TETTS 127 nrlKGQADVVICNPPYVPTEDEEVASAYQKLYQKDKLL 164 333589**********9988776665555555544555 PP == domain 2 score: 8.8 bits; conditional E-value: 0.0026 CHHHHHHHHHHHHHHHEEEEEEEEEEEETTSCHHHHHHHHHS.....--EEEEEESSE CS MTS 113 telavaeeliaeAkeaLkegGeLliVanrklgyeslleelfg.....nvevvaktkkf 165 v++++i ++ + L+++G+L+i + g+es+++++ + +++v+ k++k+ tr|Q23EX7|Q23EX7_TETTS 187 DGMVVTQNMIDTSLDLLAPNGSLYIFLIFENGVESIVKAIQQerpefKCQVLLKQRKY 244 556799*******************999999999997776654445567777777777 PP >> tr|Q22SV4|Q22SV4_TETTS Ribosomal protein L11 methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 G # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 33.1 0.1 8.7e-11 5.6e-08 21 94 .. 270 350 .. 269 357 .. 0.77 Alignments for each domain: == domain 1 score: 33.1 bits; conditional E-value: 8.7e-11 HHHHHHCHCC.....TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTTTST CS MTS 21 klLletlpke.....lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvleeve 94 klL+++l+++ +kv DlGcG G+l+ +a++ pe+++t +d+ +A++++ n + l+ ++ d++e+ + tr|Q22SV4|Q22SV4_TETTS 270 KLLAQYLQDNknylrGVEKVCDLGCGSGILSFIIAEAAPEVKITSLDKYEAAVRCTGMNSAILSLSsrIRNEIFDITEKQK 350 6899999988777654568*************************************9999988887333333334444443 PP >> tr|I7MKV3|I7MKV3_TETTS Arginine N-methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_00 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.7 0.2 1.6e-08 1.1e-05 28 103 .. 120 199 .. 111 200 .. 0.74 Alignments for each domain: == domain 1 score: 25.7 bits; conditional E-value: 1.6e-08 HCC...TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTT.TSTTS-EEEEEE CS MTS 28 pke...lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvle.eveekkfdlivs 103 +++ + + vlD+GcG+G+l++ +ak+ + +v vd +a+ + ak+ +++n+l+ +++++ + e e++ +k+d+i+s tr|I7MKV3|I7MKV3_TETTS 120 DNKnlfEGKIVLDIGCGTGILSIFAAKAGAK-HVYGVD-NANIILHAKAIVKNNNLAdkITLIQGKMEEvELPVEKVDIIIS 199 44455344559****************9888.788888.5677888899999999887666666555442445689999997 PP >> tr|Q24D55|Q24D55_TETTS Ribosomal protein L11 methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 G # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 25.9 0.0 1.4e-08 8.8e-06 31 103 .. 57 133 .. 43 188 .. 0.80 Alignments for each domain: == domain 1 score: 25.9 bits; conditional E-value: 1.4e-08 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC...EEEEE-STTTTST.TS-EEEEEE CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle...vevvasdvleeve.ekkfdlivs 103 ++++l +G+G+G+ g+a++k ++ +v+++d + l+ k+n e+n ++ +v+ + +e + +kk+d+i+ tr|Q24D55|Q24D55_TETTS 57 SNKDILEVGTGVGIGGLAALKYTECKRVDMTDYNQDVLANIKKNSEKNSISkqrYDVFYLNWFEYDKfNKKYDVIIG 133 4678*****************999999***********************9888889999987755547******96 PP >> tr|Q239D4|Q239D4_TETTS Cyclopropane-fatty-acyl-phospholipid synthase OS=Tetrahymena thermophila (strain SB210) OX=31 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.9 0.0 2.8e-08 1.8e-05 23 151 .. 35 166 .. 30 178 .. 0.77 Alignments for each domain: == domain 1 score: 24.9 bits; conditional E-value: 2.8e-08 HHHHCHCCTCSE......EEEET-TTSHHHHHHHHHTTC.E.EEEEESBHHHHHHHHHHHHHTTGCEEEEE-STT..TTSTTS-EEE CS MTS 23 Lletlpkelsgk......vlDlGcGaGvlgaalakespeae.vtlvdvdarAlesakenleanklevevvasdvl..eeveekkfdl 100 L+++l+ke+++k +lD+G G+G+ ++a++ p+++ + vd+d + +++a++ ++++k +ve++ ++ + ++ +e++fd+ tr|Q239D4|Q239D4_TETTS 35 LADYLKKEEQKKdvsldsILDIGIGTGLPLYKIASKFPQNAkILGVDIDENYVKAAQKLFKDKK-NVEIRLQNFYelDAKKEGQFDI 120 667777763333344445*********999999999988777****************999876.45555555541167889***** PP EEE---STTTCHCHHHHHHHHHHHHHHHEEEEEEEEEEEETTSCHHHHHHH CS MTS 101 ivsNPPfhagkatelavaeeliaeAkeaLkegGeLliVanrklgyesllee 151 ++ f + e+ ia Ak+ k++G++++ +++ ++l e+ tr|Q239D4|Q239D4_TETTS 121 VLFSFSFMLMPE-----REKAIALAKQLVKKDGRIIFLLTLHQKKNPLFEQ 166 **9988887777.....6777888999999999999888888887777554 PP >> tr|I7M361|I7M361_TETTS Methyltransferase-like protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_ # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.7 0.0 3.2e-08 2.1e-05 24 112 .. 51 146 .. 44 161 .. 0.64 Alignments for each domain: == domain 1 score: 24.7 bits; conditional E-value: 3.2e-08 HHHCHCCTCSE.EEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC......EEEEE-STTT.TSTTS-EEEEE CS MTS 24 letlpkelsgk.vlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle......vevvasdvle.eveekkfdliv 102 + ++++l+++ v D+GcG+G+l++ ++ + v ++ d + +++ +le++ + +++ + +++ k fd++v tr|I7M361|I7M361_TETTS 51 VAEIEENLEDQiVGDFGCGTGMLSCGMLCVGAGQ-VIGLELDSKYAQITLDTLEDKFEDpsmydiININVKHWQPpTLNGKLFDTVV 136 56677775555166***********999988774.555555555555555555554444446244444444443313445779**** PP E---STTTCH CS MTS 103 sNPPfhagka 112 +NPPf ++ + tr|I7M361|I7M361_TETTS 137 MNPPFGTKDE 146 *****87665 PP >> tr|I7MK94|I7MK94_TETTS AdoMet-dependent proline di-methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=31 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.6 0.0 3.6e-08 2.3e-05 20 102 .. 83 167 .. 72 207 .. 0.84 Alignments for each domain: == domain 1 score: 24.6 bits; conditional E-value: 3.6e-08 HHHHHHHCHCC...TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTTSTTS-EEEEE CS MTS 20 sklLletlpke...lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasdvleeveekkfdliv 102 s+ Lle l+++ g+v+D G+G+G ++ +++ + + + ++vd++ + +e++k+n+++ k v+++a+ + e ++k+d+i tr|I7MK94|I7MK94_TETTS 83 SRKLLELLHDKydlNYGRVIDCGAGMGRITKEFLLHFFK-NADVVDQNPKYIEACKQNFKDDKRVVHFIAKGLQELEFPEKYDCIW 167 677999999988888899************999887777.59*********************9999999888887779****994 PP >> tr|Q231G1|Q231G1_TETTS U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase OS=Tetrahymena thermophila (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.4 0.0 8.5e-08 5.5e-05 31 144 .. 161 281 .. 150 303 .. 0.71 Alignments for each domain: == domain 1 score: 23.4 bits; conditional E-value: 8.5e-08 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHH.....HTTGCEEEEE-STTTTST...TS-EEEEEE---STT CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenle.....anklevevvasdvleeve...ekkfdlivsNPPfha 109 + k++D+G+Ga v+ l + + + + +++ + ++ + ak+ ++ +nk+e++ + ++++++ ++++ + ++NPPf + tr|Q231G1|Q231G1_TETTS 161 NQIKAIDIGTGASVIYPILGASKYNWSFIATELSDASYQNAKKIINnnpqlKNKVELRKSQGNIFKDIIqksDGDISFTMCNPPFFS 247 45579**********999988888877666666666666666655510112455556666666666553222588999********* PP TCHCHHHHHHHHHHHHHHHEEEEEEEEEEEETTSC CS MTS 110 gkatelavaeeliaeAkeaLkegGeLliVanrklg 144 +++ e++++ + + +e+ egGeL++ + + + tr|Q231G1|Q231G1_TETTS 248 EHE-EKQIWVNAQMKENEYICEGGELQFLKQMFEE 281 *99.777887778888999*******998887655 PP >> tr|Q22MG6|Q22MG6_TETTS RNA cap guanine-N2 methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=T # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.3 0.0 1.8e-07 0.00012 25 107 .. 371 453 .. 367 464 .. 0.86 Alignments for each domain: == domain 1 score: 22.3 bits; conditional E-value: 1.8e-07 HHCHCC.TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTTTSTTS-EEEEEE---S CS MTS 25 etlpke.lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvleeveekkfdlivsNPPf 107 ++l+++ +++ v+D cG+G+ ++++ake ++ v ++d + + ak n+e+ k + vev++sd l+ + k d++v P + tr|Q22MG6|Q22MG6_TETTS 371 QYLSSRlKNQIVVDAFCGVGYNTVQFAKEASQ--VIAIDCNQVKVSHAKYNIESFKQQhkVEVIQSDFLQMKK-LKADTVVLHPDY 453 5667774456699***************9998..99****************98666666*********9988.9******99965 PP >> tr|Q24E29|Q24E29_TETTS UbiE/COQ5 family methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTH # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 23.1 0.0 1e-07 6.6e-05 15 133 .. 22 151 .. 14 184 .. 0.74 Alignments for each domain: == domain 1 score: 23.1 bits; conditional E-value: 1e-07 S--HHHHHHHHHCHCC....TCSEEEEET-TTSHHHHHHHHHTTC.E.EEEEESBHHHHHHHHHHH....HHTTGC......EEEEE CS MTS 15 klDkGsklLletlpke....lsgkvlDlGcGaGvlgaalakespeae.vtlvdvdarAlesakenl....eankle......vevva 86 + D Gs++L l + +++++l +G+G+G+l ++++ +++++ +++d++ + l++ + l ++n+++ +++ + tr|Q24E29|Q24E29_TETTS 22 SYDSGSNVLFLSLANMlkidKRDSILEVGAGTGFLYNHILNYKKQTAkYVATDISEKMLQIMSKRLkleyKENQVNnyekynLTIQK 108 689*****9888887777667888***********9988776666555*********999876655111156666666665444444 PP -STTT.TSTTS-EEEEEE---STTTCHCHHHHHHHHHHHHHHHEEEEE CS MTS 87 sdvle.eveekkfdlivsNPPfhagkatelavaeeliaeAkeaLkegG 133 ++ + +e+++fd+++ N +h + +++ e+ ++L++gG tr|Q24E29|Q24E29_TETTS 109 ANAEQlPFEQESFDCLIGNLCLHITPD-----PVKMLSESYRVLQKGG 151 444332345788999998888887777.....5677777777777777 PP >> tr|Q22RB9|Q22RB9_TETTS Methyltransferase domain protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHER # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.9 0.0 1.2e-07 7.4e-05 23 79 .. 85 145 .. 77 172 .. 0.82 Alignments for each domain: == domain 1 score: 22.9 bits; conditional E-value: 1.2e-07 HHHHCHCC....TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHH.HHHHHHTT CS MTS 23 Lletlpke....lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesa.kenleank 79 Ll++l+k+ + ++v+DlGcG G+lg+ + ++ + +v + d +++ l +a + n+ nk tr|Q22RB9|Q22RB9_TETTS 85 LLSYLHKNnfdfQGKTVMDLGCGHGLLGIYAMQQGAK-QVLFQDYNYEVLSIAvRLNIILNK 145 7888888888877788**************9998887.799999999998876355665555 PP >> tr|Q22BT0|Q22BT0_TETTS RNA cap guanine-N2 methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=T # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 22.0 0.0 2.2e-07 0.00014 21 91 .. 29 97 .. 26 112 .. 0.78 Alignments for each domain: == domain 1 score: 22.0 bits; conditional E-value: 2.2e-07 HHHHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTT CS MTS 21 klLletlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvle 91 +l+l++l++ +++ lD+GcG+G + +l ++ + + +d++ + + +a+e +++n+ v+v+++d+ + tr|Q22BT0|Q22BT0_TETTS 29 ELILQNLNS--KENYLDVGCGTGQMLFKLNSHFKF--AVGTDISEKQVSVANEKIANNQEYsnVKVIQCDANN 97 578999998..6679********987777776655..799***************999976676666655433 PP >> tr|I7MGH3|I7MGH3_TETTS RNA cap guanine-N2 methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=T # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.8 0.0 1.1e-06 0.0007 35 108 .. 323 401 .. 284 421 .. 0.83 Alignments for each domain: == domain 1 score: 19.8 bits; conditional E-value: 1.1e-06 EEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC...EEEEE-STTT....TSTTS-EEEEEE---ST CS MTS 35 vlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle...vevvasdvle....eveekkfdlivsNPPfh 108 ++D +cG+G ++++ k ++ v +vd+++rA++ ++en++++k + ve+++ d l+ e+ + + d++ NP + tr|I7MGH3|I7MGH3_TETTS 323 LIDACCGIGGNTVQFSKINKF--VFAVDQSYRAIKTCNENIKNHKQDvsnVEFIQADFLSlecgELGQLRADIVFINPQID 401 79*******999999998887..9********************99999999*****987444456678899999999765 PP >> tr|I7MAE9|I7MAE9_TETTS UbiE/COQ5 family methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTH # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.1 0.0 1.7e-06 0.0011 31 143 .. 51 160 .. 43 177 .. 0.71 Alignments for each domain: == domain 1 score: 19.1 bits; conditional E-value: 1.7e-06 TCSEEEEET-TTSHHHHHHHHHTTC..EEEEEESBHHHHHHHHHHHHHTT.GCEEEEE-STTTTSTTS-EEEEEE---STTTCHCHH CS MTS 31 lsgkvlDlGcGaGvlgaalakespe.aevtlvdvdarAlesakenleank.levevvasdvleeveekkfdlivsNPPfhagkatel 115 +++lD+G G+G ++ ++ p+ ++vt +d+d++ + +ak+ ++++ +e+++++ +e+ + k+d+i+ f + tr|I7MAE9|I7MAE9_TETTS 51 NFKRILDVGVGTGHPLYSIIDRIPKsVQVTGIDIDTNYIPAAKKIFSKHSnVEIKYMNFYDMEKEKTLKYDVIIFSSSFMLMPD--- 134 5678*********866666666665166***************99987651445555544444444579*****8777766665... PP HHHHHHHHHHHHHEEEEEEEEEEEETTS CS MTS 116 avaeeliaeAkeaLkegGeLliVanrkl 143 + ++ Ak+ L+++G++++ + ++ tr|I7MAE9|I7MAE9_TETTS 135 --RIKALEIAKNLLADNGKIYFLMTLFQ 160 ..33446778888888888877766555 PP >> tr|I7M6M7|I7M6M7_TETTS Methyltransferase domain protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHER # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 19.1 0.0 1.8e-06 0.0012 23 81 .. 63 126 .. 52 155 .. 0.69 Alignments for each domain: == domain 1 score: 19.1 bits; conditional E-value: 1.8e-06 HHHHCHCC........TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC CS MTS 23 Lletlpke........lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle 81 L+++l k+ + +++l lGcG+G l++ la++ + v+++d + + ++nl+ nk tr|I7M6M7|I7M6M7_TETTS 63 LAKYLLKQndegnyklRGKNILELGCGTGCLSIFLASQGAN--VVATDLKIT-QNYVEKNLQMNKEL 126 55555444455566667788****************98877..777776654.35556666666544 PP >> tr|Q24GH8|Q24GH8_TETTS rRNA adenine N(6)-methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TT # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.6 0.0 2.5e-06 0.0016 31 141 .. 39 150 .. 18 174 .. 0.77 Alignments for each domain: == domain 1 score: 18.6 bits; conditional E-value: 2.5e-06 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTTTSTTS-EEEEEE---STTTCHCHH CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvleeveekkfdlivsNPPfhagkatel 115 ++ vl +G G+G l+a l+++ ++ v +v++d r ++ ++ ++ ++++ e+++ d++++ fd+ v N P++ ++ tr|Q24GH8|Q24GH8_TETTS 39 PTDIVLEIGPGTGNLTALLLEKAKK--VIAVEIDPRMVAELNKRFKYSQHAhkFELIQGDAISTEF-PFFDVCVANTPYQISSPLVF 122 45669****************9998..78888888888877777666555555*********9999.89*********998875544 PP HH..HHHHHHHHHHHEEEEEEEEEEEET CS MTS 116 av..aeeliaeAkeaLkegGeLliVanr 141 ++ + l+++A + +++ +++Va+ tr|Q24GH8|Q24GH8_TETTS 123 KLlsHRPLFRHAVLMFQKEFAMRCVAKP 150 4411445888888888888888887765 PP >> tr|I7M457|I7M457_TETTS NOL1/NOP2/sun family protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_00 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.6 0.0 5.1e-06 0.0033 15 102 .. 116 206 .. 109 209 .. 0.91 2 ? -2.0 0.0 5.4 3.5e+03 60 84 .. 234 258 .. 215 271 .. 0.53 Alignments for each domain: == domain 1 score: 17.6 bits; conditional E-value: 5.1e-06 S--HHHHHHHHHCHCCTCSEEEEET-TTSHHHHHHHHHTT.C.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTTTSTTS-E CS MTS 15 klDkGsklLletlpkelsgkvlDlGcGaGvlgaalakesp.eaevtlvdvdarAlesakenleankle..vevvasdvleeveekkf 98 ++D s+ ++ l+ ++ +kvlDl+c G+ +++a+ e + vd++ l+ ++ +++ kl+ +++ d++ +e +f tr|I7M457|I7M457_TETTS 116 GIDLSSAAVIKSLDPQKGEKVLDLCCCPGMKLCNIADIIGaEGKAFGVDINETRLNTCRSIVKKYKLDhiIKLELADGTTYNKESQF 202 59***************************988888887651566999*********************9999999*****9999*** PP EEEE CS MTS 99 dliv 102 d ++ tr|I7M457|I7M457_TETTS 203 DRVL 206 *997 PP == domain 2 score: -2.0 bits; conditional E-value: 5.4 EEESBHHHHHHHHHHHHHTTGCEEE CS MTS 60 lvdvdarAlesakenleanklevev 84 + ++ ++ ++ ++nl +++ ++++ tr|I7M457|I7M457_TETTS 234 MQNNAKETIDNNEQNLDKKQNNLDF 258 3333333444444454444444444 PP >> tr|W7X0Z1|W7X0Z1_TETTS UbiE/COQ5 methyltransferase, putative OS=Tetrahymena thermophila (strain SB210) OX=312017 GN= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.7 0.0 4.7e-06 0.003 17 68 .. 23 79 .. 18 105 .. 0.80 2 ? -1.3 0.0 3.3 2.1e+03 119 135 .. 136 152 .. 130 164 .. 0.86 Alignments for each domain: == domain 1 score: 17.7 bits; conditional E-value: 4.7e-06 -HHHHH....HHHHCHCCTCSEEEEET-TTSHH.HHHHHHHTTC.EEEEEESBHHHH CS MTS 17 DkGskl....LletlpkelsgkvlDlGcGaGvl.gaalakespeaevtlvdvdarAl 68 D G+++ Ll+ l+ e+++++l +G+GaG+l + +l +++pea+ t++dv+ + l tr|W7X0Z1|W7X0Z1_TETTS 23 DHGANVfylsLLNMLKIEKRNSILEVGAGAGFLySHTLNRKKPEAKYTATDVSVKML 79 6666652222677777779999**********967788999***********98765 PP == domain 2 score: -1.3 bits; conditional E-value: 3.3 HHHHHHHHHHEEEEEEE CS MTS 119 eeliaeAkeaLkegGeL 135 +++++e+ ++L++gG tr|W7X0Z1|W7X0Z1_TETTS 136 QKMLNESYRVLQKGGVV 152 7899**********975 PP >> tr|Q235D9|Q235D9_TETTS Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Tetrahymena thermophila (strain # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.3 0.0 3.1e-06 0.002 31 80 .. 404 451 .. 395 522 .. 0.76 Alignments for each domain: == domain 1 score: 18.3 bits; conditional E-value: 3.1e-06 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTG CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankl 80 ++ ++lD+GcG G+l+ +l + + vt +d++ +++ +a++ + ++ tr|Q235D9|Q235D9_TETTS 404 KNLQILDVGCGGGLLSESLCRLGAN--VTGLDANENSISIANNHKKLDQF 451 4567*****************9988..9************9988776654 PP >> tr|I7LTA0|I7LTA0_TETTS Methyltransferase domain protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHER # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.4 0.0 5.8e-06 0.0037 31 139 .. 41 150 .. 29 164 .. 0.82 2 ? -1.6 0.0 3.9 2.5e+03 91 132 .. 229 272 .. 222 275 .. 0.63 Alignments for each domain: == domain 1 score: 17.4 bits; conditional E-value: 5.8e-06 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTT.TSTTS-EEEEEE---STTTC..HCH CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasdvle.eveekkfdlivsNPPfhagk..ate 114 ++g +l lGcG+ v+ ++ + + ++ +d++ + ++ + n+ e+ + d++e + e++kfd+++ + a + + tr|I7LTA0|I7LTA0_TETTS 41 KDGIILNLGCGNSVIQEEMYDDGYK-NIYNIDISEECIKQMD-SRKGNRPELIYEVMDCTElKYEDEKFDFVIDKSTIDALLcgDYS 125 56779**************998777.799*********9876.46788888777777776635678************998744566 PP HHHHHHHHHHHHHHEEEEEEEEEEE CS MTS 115 lavaeeliaeAkeaLkegGeLliVa 139 + + +++ e +++Lk++G liV tr|I7LTA0|I7LTA0_TETTS 126 YLNVAKMMSEVQRVLKPNGVYLIVS 150 777899**************99997 PP == domain 2 score: -1.6 bits; conditional E-value: 3.9 TTSTTS-EEEEEE---STTTC..HCHHHHHHHHHHHHHHHEEEE CS MTS 91 eeveekkfdlivsNPPfhagk..atelavaeeliaeAkeaLkeg 132 + ++ ++ +i+ P ++k + ++v+ eli+e keaLk tr|I7LTA0|I7LTA0_TETTS 229 GQKQNPHYAYILKKGPNAQQKyeNNYEEVILELIEEEKEALKLY 272 55566677777777776666632334567788888888887755 PP >> tr|Q23MB9|Q23MB9_TETTS tRNA (guanine-N(7)-)-methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.9 0.0 8.4e-06 0.0054 33 139 .. 116 237 .. 96 259 .. 0.71 Alignments for each domain: == domain 1 score: 16.9 bits; conditional E-value: 8.4e-06 SEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC........EEEEE-STTTTS....TT...S-EEEEEE- CS MTS 33 gkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle........vevvasdvleev....ee...kkfdlivsN 104 lD+GcG+G l +lak+ pe v +++ + ++ e ++a ++e + ++ ++++ ++ + +k+ + tr|Q23MB9|Q23MB9_TETTS 116 PVFLDIGCGFGGLVFNLAKNFPEKLVLGLEIRDKLVNYVSEKIKALRIEspdhkynnAACIRTNAMRHIiqyfRKgtiEKMFFCFAD 202 4579*******************9898899888888888888888777766655555444444443332111122111455566678 PP --STTTCHCHHHHHHHHHHHHHHHEEEEEEEEEEE CS MTS 105 PPfhagkatelavaeeliaeAkeaLkegGeLliVa 139 P f+++++ + + + ++ e + Lk++G++++++ tr|Q23MB9|Q23MB9_TETTS 203 PHFKKSNHRRRIINTGFLSEYAFLLKPKGRIYCIT 237 88888888888888888888888888888888775 PP >> tr|I7M9J8|I7M9J8_TETTS NOL1/NOP2/Sun family protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_00 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.3 0.0 6.3e-06 0.004 17 106 .. 197 291 .. 192 301 .. 0.87 Alignments for each domain: == domain 1 score: 17.3 bits; conditional E-value: 6.3e-06 -HHHHHHHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.E.EEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTT...S-E CS MTS 17 DkGsklLletlpkelsgkvlDlGcGaGvlgaalakespeae.vtlvdvdarAlesakenleankle.vevvasdvleevee...kkf 98 D +s+l + +++ ++ ++vlD ++GaG ++a+a + + + l d + l+ ak+ +++ +++ v++++++ l++ ++ kkf tr|I7M9J8|I7M9J8_TETTS 197 DEASQLAAFKVKCQIGDHVLDYCAGAGGKSLAFAPYLKGTGqIYLHDTRDYILQEAKKRFNKAGIQnVQFHTQESLNNNKNklvKKF 283 88999999999999****************999977665544************************99**99999988875333799 PP EEEEE--- CS MTS 99 dlivsNPP 106 d++v+ P tr|I7M9J8|I7M9J8_TETTS 284 DWVVCDVP 291 ***99766 PP >> tr|I7M1S8|I7M1S8_TETTS tRNA (Uracil-5)-methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHE # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.2 0.0 1.3e-05 0.0084 32 90 .. 532 589 .. 520 623 .. 0.77 Alignments for each domain: == domain 1 score: 16.2 bits; conditional E-value: 1.3e-05 CSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STT CS MTS 32 sgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdvl 90 + lD+++G+G +g+ la+ +e v ++ A + ak n+e+n++ +v+ s v tr|I7M1S8|I7M1S8_TETTS 532 KTIFLDICSGIGTIGICLANSAKE--VIGIEMVETACNDAKINIEQNGITnYKVICSKVE 589 33479***************9888..555666668999*********9997666555443 PP >> tr|Q24FF7|Q24FF7_TETTS Methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_00865060 PE=4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.8 0.1 8.7e-06 0.0056 27 102 .. 57 140 .. 43 142 .. 0.72 Alignments for each domain: == domain 1 score: 16.8 bits; conditional E-value: 8.7e-06 CHCC....TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC....EEEEE-ST..TTTSTTS-EEEEE CS MTS 27 lpke....lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle....vevvasdv..leeveekkfdliv 102 + ++ +++ vl +G+G+G+ g+++a+ ++ v ++d + e+ + n++ + + ++ + d+ le+ ++ kfd+i+ tr|Q24FF7|Q24FF7_TETTS 57 IVENkeifRDKVVLEVGAGVGLSGLVCAQYAKQ--VYITDGNDIVCELMEMNAQYAQNNnvvmEKYCWGDLsyLEKRKDIKFDIII 140 4444445467789****************9998..777777777777777776543333333678899986446888899999998 PP >> tr|Q24D56|Q24D56_TETTS UbiE/COQ5 methyltransferase, putative OS=Tetrahymena thermophila (strain SB210) OX=312017 GN= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 17.2 0.0 6.5e-06 0.0042 23 74 .. 35 87 .. 17 111 .. 0.81 Alignments for each domain: == domain 1 score: 17.2 bits; conditional E-value: 6.5e-06 HHHHCHCCTCSEEEEET-TTSHH.HHHHHHHTTC.EEEEEESBHHHHHHHHHH CS MTS 23 LletlpkelsgkvlDlGcGaGvl.gaalakespeaevtlvdvdarAlesaken 74 Ll+ l+ ++++++l +G+GaG+l ++ + pea+ +++d + + l + + tr|Q24D56|Q24D56_TETTS 35 LLNMLKVNTRKQILEVGAGAGFLyNHTMNYKRPEASYVATDLSEKMLSILCKR 87 78999999**************9445688899*********999887765555 PP >> tr|I7M1Y0|I7M1Y0_TETTS Protein-L-isoaspartate O-methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=31201 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 16.0 0.0 1.5e-05 0.0099 31 78 .. 109 161 .. 94 229 .. 0.74 Alignments for each domain: == domain 1 score: 16.0 bits; conditional E-value: 1.5e-05 TCSEEEEET-TTSHHHHHHHHHTT.....C.EEEEEESBHHHHHHHHHHHHHT CS MTS 31 lsgkvlDlGcGaGvlgaalakesp.....eaevtlvdvdarAlesakenlean 78 + +vlD+GcG+G+l a++k+ p + +++ +d + ++++ +n++++ tr|I7M1Y0|I7M1Y0_TETTS 109 KPVRVLDIGCGTGYLCPAFLKMIPvqfqqQSTIVGIDHVKDLVQLSDRNIRKS 161 4456***********99888775522221455778888888888888888765 PP >> tr|W7XD08|W7XD08_TETTS tRNA (guanine(37)-N1)-methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 G # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.5 0.0 2.3e-05 0.015 31 89 .. 223 281 .. 204 290 .. 0.82 Alignments for each domain: == domain 1 score: 15.5 bits; conditional E-value: 2.3e-05 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-ST CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdv 89 +++vlDl cG+G+l++ +ak+ + v + d + + + n e+n++e + ++++d+ tr|W7XD08|W7XD08_TETTS 223 PNETVLDLFCGVGPLAIRAAKMGCK--VICNDLNPHCYDYLLINREKNNVEdkTLCFNNDA 281 4678*****************9887..9999****99999999999999996555555554 PP >> tr|Q236L4|Q236L4_TETTS L-isoaspartate O-methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTH # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -2.6 0.0 8.3 5.4e+03 58 81 .. 90 113 .. 75 126 .. 0.71 2 ! 14.1 0.0 5.9e-05 0.038 27 55 .. 141 171 .. 135 229 .. 0.85 Alignments for each domain: == domain 1 score: -2.6 bits; conditional E-value: 8.3 EEEEESBHHHHHHHHHHHHHTTGC CS MTS 58 vtlvdvdarAlesakenleankle 81 + +d d A++ +++ +++n l+ tr|Q236L4|Q236L4_TETTS 90 FNELDRDLFAINKSQKIYANNPLS 113 556788888888888888887765 PP == domain 2 score: 14.1 bits; conditional E-value: 5.9e-05 CHCC..TCSEEEEET-TTSHHHHHHHHHTTC CS MTS 27 lpke..lsgkvlDlGcGaGvlgaalakespe 55 l+++ + k+lD+GcG G+++ a+ k ++ tr|Q236L4|Q236L4_TETTS 141 LKQKkgSEIKILDIGCGRGYIAFAISKIIEK 171 4444346668*************99886655 PP >> tr|W7XK56|W7XK56_TETTS Actin-related protein 2/3 complex subunit 5 OS=Tetrahymena thermophila (strain SB210) OX=3120 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.8 0.3 1.8e-05 0.011 64 123 .. 7 65 .. 2 99 .. 0.88 Alignments for each domain: == domain 1 score: 15.8 bits; conditional E-value: 1.8e-05 BHHHHHHHHHHHHHTTGCEEEEE-STTTTSTTS-EEEEEE---STTTCHCHHHHHHHHHH CS MTS 64 darAlesakenleanklevevvasdvleeveekkfdlivsNPPfhagkatelavaeelia 123 +a+ le+ +e l+a + +++++++ + ++v +k+ +++ NPP++++++++l+ +l++ tr|W7XK56|W7XK56_TETTS 7 NAKQLEAEQEALKAYEEKMTLLKNAANQDVV-QKMKIVIDNPPVKSKNQETLEKYVALFH 65 778899999999999999*****9999***9.**************99988776666665 PP >> tr|I7M351|I7M351_TETTS Kinase domain protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_00558360 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.7 0.0 2e-05 0.013 31 140 .. 40 151 .. 32 172 .. 0.78 Alignments for each domain: == domain 1 score: 15.7 bits; conditional E-value: 2e-05 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTT.TSTTS-EEEEEE---STTTC..HCH CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasdvle.eveekkfdlivsNPPfhagk..ate 114 + k+l +G+G l+ ++ +e + ++t +d++ +s +e +++++ + ++++ dv + e+e k+fd+++ + + + + tr|I7M351|I7M351_TETTS 40 PESKILNVGSGSSRLSEEMFDEGHQ-NITNIDISSIVTKSMQEKYKDKGPNFKYLQMDVRNmEFEAKSFDCVMDKGTLDSILcgESS 125 4678****************98777.8********************************873678999***9976665554333445 PP HHHHHHHHHHHHHHEEEEEEEEEEEE CS MTS 115 lavaeeliaeAkeaLkegGeLliVan 140 ++ a++ i e ++L+++G +++ tr|I7M351|I7M351_TETTS 126 TSNANKAISEIYRVLTPKGVYVLISH 151 55566666666666666666666655 PP >> tr|Q245D9|Q245D9_TETTS UbiE/COQ5 family methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTH # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.5 0.0 4.4e-05 0.028 30 102 .. 49 128 .. 38 181 .. 0.63 Alignments for each domain: == domain 1 score: 14.5 bits; conditional E-value: 4.4e-05 CTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.......EEEEE.-STTTTST.TS-EEEEE CS MTS 30 elsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.......vevva.sdvleeve.ekkfdliv 102 ++ lD++cG+G l +l+++ ++ +d++ + l + +e +++n+l+ +++++ ++l+e + + kfdli tr|Q245D9|Q245D9_TETTS 49 GDKKAYLDIACGTGQLLFQLQNHFEK--SIGTDISEKQLSVVEELIKSNNLSnsvysikADCHQlPNILQEKNlPTKFDLIT 128 367789**************999988..567899999999999999999988553333322222123333333356666665 PP >> tr|Q23VZ1|Q23VZ1_TETTS UbiE/COQ5 methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_007 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.9 0.0 7.1e-05 0.045 23 133 .. 43 160 .. 30 196 .. 0.71 Alignments for each domain: == domain 1 score: 13.9 bits; conditional E-value: 7.1e-05 HHHHCHCCTCSEEEEET-TTSHHH.HHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC........EEEEE-STT..T.TSTTS- CS MTS 23 LletlpkelsgkvlDlGcGaGvlg.aalakespeaevtlvdvdarAlesakenleankle........vevvasdvl..e.eveekk 97 L++ l+ e+++++l +G+G G+l +l++++pea+ ++d++ l+ + + + +++ s++ + ++++ tr|Q23VZ1|Q23VZ1_TETTS 43 LINMLKLEERKNILEVGAGGGFLYnHSLQRKHPEANYYATDISDSMLDTLCKRMGGQYTPtqttyipnYKLHISNANgeQlPFKDET 129 78899999999***********9615678899**********999988654443322222223344554444444431032345777 PP EEEEEE---STTTCHCHHHHHHHHHHHHHHHEEEEE CS MTS 98 fdlivsNPPfhagkatelavaeeliaeAkeaLkegG 133 fd+ ++N ++ ++ ++++ eA ++L++gG tr|Q23VZ1|Q23VZ1_TETTS 130 FDCYICNLCLQITTN-----PDKMLSEAIRVLQKGG 160 888888876666665.....6677777777777777 PP >> tr|Q23EY2|Q23EY2_TETTS UbiE/COQ5 methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_006 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.1 0.0 0.00012 0.078 23 88 .. 54 121 .. 52 179 .. 0.62 2 ? -2.5 0.1 7.7 4.9e+03 63 80 .. 254 271 .. 239 284 .. 0.71 Alignments for each domain: == domain 1 score: 13.1 bits; conditional E-value: 0.00012 HHHHCHCCTCSEEEEET-TTSHH.HHHHHHHTTC.EEEEEESBHHHHHHH..HHHHHHTTGCEEEEE-S CS MTS 23 LletlpkelsgkvlDlGcGaGvl.gaalakespeaevtlvdvdarAlesa..kenleanklevevvasd 88 Ll+ ++ ++++k+l +G+G G+l al+ ++p+ae ++d + + l++ + nl++ + + v ++ tr|Q23EY2|Q23EY2_TETTS 54 LLNMIKFDQRNKILEVGAGGGYLlNHALKYKKPSAEYFATDLSENMLKILcrRMNLQDCLSN-QQVSQN 121 77888888999**********972567788999***99999988887754115555543322.222222 PP == domain 2 score: -2.5 bits; conditional E-value: 7.7 SBHHHHHHHHHHHHHTTG CS MTS 63 vdarAlesakenleankl 80 ++ +A+es+ en e+ k tr|Q23EY2|Q23EY2_TETTS 254 NNLQAIESTGENKEKVKQ 271 577888888888776554 PP >> tr|I7M2L9|I7M2L9_TETTS Methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_00305590 PE=4 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.8 0.0 7.4e-05 0.048 27 71 .. 46 88 .. 40 104 .. 0.80 Alignments for each domain: == domain 1 score: 13.8 bits; conditional E-value: 7.4e-05 CHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHH CS MTS 27 lpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesa 71 +p+ +++ +lD+GcG G+ ga+l +++ + + +d++ l++a tr|I7M2L9|I7M2L9_TETTS 46 IPEGEDQLILDIGCGSGLSGAQLSEHNHH--WVGIDISRDMLNVA 88 55657788****************98887..67888887777665 PP >> tr|I7M0Y7|I7M0Y7_TETTS Embryo-abundant protein, putative OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHE # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.2 0.0 0.00011 0.071 27 90 .. 35 99 .. 28 119 .. 0.81 Alignments for each domain: == domain 1 score: 13.2 bits; conditional E-value: 0.00011 CHCC.TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STT CS MTS 27 lpke.lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvl 90 l+++ +++ +D++cG+G l +l ++ + +d++ + +e++++ +++++l+ v+++ +d+ tr|I7M0Y7|I7M0Y7_TETTS 35 LKHAvDRENFVDIACGTGQLLFELSNHFKF--SLGTDISPKQIEVTNQKIQKKNLQdrVKAIVCDAH 99 4444566789**********9999887766..5789******************9988777777765 PP >> tr|I7M390|I7M390_TETTS L-isoaspartate O-methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTH # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 14.3 0.0 5.2e-05 0.033 26 101 .. 289 375 .. 284 400 .. 0.75 Alignments for each domain: == domain 1 score: 14.3 bits; conditional E-value: 5.2e-05 HCHCC..TCSEEEEET-TTSHHHHHHHHHTTC.E..EEEEESBHHHHHHHHHHHHHTTGC......EEEEE-STTTTSTT.S-EEEE CS MTS 26 tlpke..lsgkvlDlGcGaGvlgaalakespeae..vtlvdvdarAlesakenleankle......vevvasdvleevee.kkfdli 101 l+++ +s k lD+G G G +++alak ++ + +d l+++k+n+ +n+ e + +v+ d+ e +e+ + fd+i tr|I7M390|I7M390_TETTS 289 ILKEHaqESMKCLDIGIGSGWMTTALAKLMKDESaiCYGLDHLQGVLNISKKNIMKNHKEllesgkIVLVKGDGREGLEDyAPFDII 375 55555446778*****************9999883345567777899*********9988877877777888888888742456654 PP >> tr|I7MLB3|I7MLB3_TETTS Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family protein OS=Tetrahyme # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 3.6 0.1 0.1 67 118 157 .. 268 307 .. 260 311 .. 0.82 2 ? 7.9 0.0 0.0049 3.1 100 117 .. 312 329 .. 305 343 .. 0.72 Alignments for each domain: == domain 1 score: 3.6 bits; conditional E-value: 0.1 HHHHHHHHHHHEEEEEEEEEEEETTSCHHHHHHHHHS--E CS MTS 118 aeeliaeAkeaLkegGeLliVanrklgyeslleelfgnve 157 a+el+ + L ++G+ ++V+ r + +e+ll ++f++ + tr|I7MLB3|I7MLB3_TETTS 268 AQELMIQTGLELIKNGDVILVYARSQVVENLLLTAFKKGK 307 56677777778999*********************99866 PP == domain 2 score: 7.9 bits; conditional E-value: 0.0049 EEEE---STTTCHCHHHH CS MTS 100 livsNPPfhagkatelav 117 ++v NPPfh+gk +++ tr|I7MLB3|I7MLB3_TETTS 312 IVVDNPPFHEGKLLLQKL 329 4678*******9755555 PP >> tr|Q24E30|Q24E30_TETTS UbiE/COQ5 methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_008 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.9 0.0 0.00028 0.18 15 70 .. 22 82 .. 15 158 .. 0.76 Alignments for each domain: == domain 1 score: 11.9 bits; conditional E-value: 0.00028 S--HHHHH....HHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.E.EEEEESBHHHHHH CS MTS 15 klDkGskl....LletlpkelsgkvlDlGcGaGvlgaalakespeae.vtlvdvdarAles 70 ++D+Gs+l L++ l+ + ++++l +G+GaG+l + +++++ + ++d + + l+ tr|Q24E30|Q24E30_TETTS 22 NMDNGSSLfylsLINMLKIQDRKSILEVGAGAGFLFNHTMNFKKHGAqYIATDLSEKMLQY 82 579999984333456666668889***********88877776665447778877776665 PP >> tr|W7X1L8|W7X1L8_TETTS AdoMet-dependent proline di-methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=31 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.0 0.00044 0.28 20 133 .. 89 204 .. 80 217 .. 0.72 2 ? -1.3 0.0 3.1 2e+03 47 76 .. 244 273 .. 241 276 .. 0.83 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00044 HHHHHHHCHCC......TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTTSTTS-EEE CS MTS 20 sklLletlpke......lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasdvleeveekkfdl 100 s+ +l++l+++ +++lD G+G+G ++ +l+ + + +v+l+++ + + ak+ l++ ++++ + e +k++d+ tr|W7X1L8|W7X1L8_TETTS 89 SRYFLQQLQEKfpqlsqNFNRALDCGAGIGRVTKELLMNVFQ-KVDLLEQCDKYIFEAKNQLKQYPNVEDFYQMGLQEFQFQKQYDC 174 667778888777776655667**************9997777.89***999999999999998876555666666655555899999 PP EEE---STTTCHCHHHHHHHHHHHHHHHEEEEE CS MTS 101 ivsNPPfhagkatelavaeeliaeAkeaLkegG 133 i +++++++ +++++ + L+++G tr|W7X1L8|W7X1L8_TETTS 175 IWIQ---WVSNQIKDDDYVRFLQKCSNSLSQDG 204 9664...23334445555666666666666666 PP == domain 2 score: -1.3 bits; conditional E-value: 3.1 HHHHHHTTC.EEEEEESBHHHHHHHHHHHH CS MTS 47 aalakespeaevtlvdvdarAlesakenle 76 + l k++pe +l+dv+++Al+ en + tr|W7X1L8|W7X1L8_TETTS 244 IILEKKQPEFPDELFDVKMYALKRISENKN 273 6788999999999*********98888765 PP >> tr|W7XIC4|W7XIC4_TETTS UbiE/COQ5 methyltransferase OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_000 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 9.3 0.0 0.0017 1.1 23 133 .. 59 176 .. 48 204 .. 0.69 Alignments for each domain: == domain 1 score: 9.3 bits; conditional E-value: 0.0017 HHHHCHCCTCSEEEEET-TTSHHH.HHHHHHTTC.EEEEEESBHHHH..HHHHHHHH..HTTGC......EEEEE-STTT.TSTTS- CS MTS 23 LletlpkelsgkvlDlGcGaGvlg.aalakespeaevtlvdvdarAl..esakenle..ankle......vevvasdvle.eveekk 97 L++ l+ e++ ++l +G+G G+l +l +++p+ + ++d + l + + +e n+l +++ + ++ + + +++ tr|W7XIC4|W7XIC4_TETTS 59 LINMLKIEKRMNILEVGAGGGFLYnHSLNRKHPNSNYYATDLSDSMLgiLCKRIGVEykPNQLItipnynLHIEKANGEKlHYKNEM 145 788888889999**********96156778899999999998765541044444443103333355554445555555442345677 PP EEEEEE---STTTCHCHHHHHHHHHHHHHHHEEEEE CS MTS 98 fdlivsNPPfhagkatelavaeeliaeAkeaLkegG 133 fd+ + N ++ ++ e++i+eA+++L++gG tr|W7XIC4|W7XIC4_TETTS 146 FDCYIANLCLQITTN-----PEKMIQEANRVLQPGG 176 777777776666665.....6778888888888887 PP >> tr|I7MDA5|I7MDA5_TETTS Uncharacterized protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_0054829 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.4 0.1 0.00039 0.25 112 161 .. 34 82 .. 13 90 .. 0.82 Alignments for each domain: == domain 1 score: 11.4 bits; conditional E-value: 0.00039 HCHHHHHHHHHHHHHHHEEEEEEEEEEEETTSCHHHHHHHHHS--EEEEE CS MTS 112 atelavaeeliaeAkeaLkegGeLliVanrklgyeslleelfgnvevvak 161 ++el++ +e++++ k++L++ G+L+ nr+ ++++ l++ f+ ++ + tr|I7MDA5|I7MDA5_TETTS 34 QKELRILQEMMRKCKQVLRDLGDLIKEENREKRVQN-LKQFFKLCTKTME 82 456899******************999999988876.6999997766544 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (169 nodes) Target sequences: 26971 (16912921 residues searched) Passed MSV filter: 1466 (0.0543547); expected 539.4 (0.02) Passed bias filter: 598 (0.022172); expected 539.4 (0.02) Passed Vit filter: 77 (0.00285492); expected 27.0 (0.001) Passed Fwd filter: 42 (0.00155723); expected 0.3 (1e-05) Initial search space (Z): 26971 [actual number of targets] Domain search space (domZ): 42 [number of targets reported over threshold] # CPU time: 0.34u 0.02s 00:00:00.36 Elapsed: 00:00:00.18 # Mc/sec: 15879.35 // [ok]