# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/MTS.hmm.txt
# target sequence database: proteomes/Thermococcus_kodakarensis.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: MTS [M=169]
Accession: PF05175.13
Description: Methyltransferase small domain
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
6.3e-45 149.8 0.0 7.2e-45 149.7 0.0 1.0 1 tr|Q5JJF0|Q5JJF0_THEKO Ribosomal RNA small subunit methyltra
2e-18 63.6 0.0 1.3e-17 61.0 0.0 1.9 1 tr|Q5JIX8|Q5JIX8_THEKO N5-glutamine methyltransferase, HemK
1.2e-15 54.6 0.0 1.7e-15 54.1 0.0 1.2 1 tr|Q5JDP7|Q5JDP7_THEKO Predicted DNA methylase OS=Thermococc
6.4e-12 42.4 0.0 1e-11 41.8 0.0 1.3 1 tr|Q5JFS6|Q5JFS6_THEKO Predicted SAM-dependent methyltransfe
4.9e-11 39.6 0.0 8.5e-11 38.8 0.0 1.3 1 tr|Q5JE68|Q5JE68_THEKO 23S rRNA (Uracil-5-)-methyltransferas
7.2e-11 39.0 0.0 1.1e-10 38.4 0.0 1.3 1 tr|Q5JHF7|Q5JHF7_THEKO 23S rRNA (Uracil-5-)-methyltransferas
1.7e-09 34.6 0.0 2.5e-09 34.0 0.0 1.2 1 tr|Q5JGN8|Q5JGN8_THEKO SAM-dependent methyltransferase, UbiE
3.8e-09 33.4 0.0 2.4e-06 24.3 0.0 2.0 2 tr|Q5JJ79|Q5JJ79_THEKO Predicted SAM-dependent methyltransfe
2e-08 31.0 0.0 3.2e-08 30.4 0.0 1.2 1 tr|Q5JHQ2|Q5JHQ2_THEKO SAM-dependent methyltransferase, UbiE
3.3e-08 30.4 0.0 5.3e-08 29.7 0.0 1.3 1 tr|Q5JDR0|Q5JDR0_THEKO SAM-dependent methyltransferase, UPF0
1.1e-07 28.7 0.0 4.5e-05 20.2 0.0 3.1 2 tr|Q5JDB4|Q5JDB4_THEKO tRNA/rRNA cytosine-C5-methylase, NOL1
1.6e-06 24.9 0.1 2.9e-06 24.1 0.1 1.3 1 tr|Q5JEU8|Q5JEU8_THEKO Predicted SAM-dependent methyltransfe
1.8e-06 24.7 0.0 2.9e-06 24.0 0.0 1.3 1 tr|Q5JJ78|Q5JJ78_THEKO Probable tRNA/rRNA methyltransferase
2e-05 21.3 0.0 3.5e-05 20.5 0.0 1.4 1 tr|Q5JD70|Q5JD70_THEKO Met-10+ like protein OS=Thermococcus
8.7e-05 19.2 0.0 0.00017 18.3 0.0 1.5 1 tr|Q5JGS7|Q5JGS7_THEKO tRNA (1-methyladenosine) methyltransf
0.00014 18.6 0.0 0.00021 18.0 0.0 1.3 1 sp|Q5JI54|RSMA_THEKO Probable ribosomal RNA small subunit
0.00016 18.4 0.0 0.00026 17.7 0.0 1.2 1 tr|Q5JEE1|Q5JEE1_THEKO Protein-L-isoaspartate O-methyltransf
0.00025 17.8 0.0 0.00038 17.1 0.0 1.2 1 tr|Q5JEM0|Q5JEM0_THEKO Predicted N6-adenine-specific DNA met
0.00029 17.5 0.0 0.00049 16.8 0.0 1.2 1 tr|Q5JH73|Q5JH73_THEKO Uncharacterized protein OS=Thermococc
0.00047 16.9 0.0 0.012 12.3 0.0 2.2 1 tr|Q5JDP5|Q5JDP5_THEKO tRNA/rRNA cytosine-C5-methylase, NOL1
0.0011 15.6 0.0 0.0017 15.0 0.0 1.2 1 tr|Q5JID5|Q5JID5_THEKO N2, N2-dimethylguanosine tRNA methylt
0.0047 13.6 0.0 4.3 4.0 0.0 3.8 4 tr|Q5JH54|Q5JH54_THEKO Predicted endonuclease-methyltransfer
0.0099 12.5 0.0 0.085 9.5 0.0 2.0 2 tr|Q5JFQ4|Q5JFQ4_THEKO SAM-dependent methyltransferase, UbiE
------ inclusion threshold ------
0.023 11.4 0.0 0.051 10.2 0.0 1.5 1 tr|Q5JED8|Q5JED8_THEKO SAM-dependent methyltransferase, UbiE
Domain annotation for each sequence (and alignments):
>> tr|Q5JJF0|Q5JJF0_THEKO Ribosomal RNA small subunit methyltransferase C OS=Thermococcus kodakarensis (strain ATCC BAA
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 149.7 0.0 7.6e-47 7.2e-45 3 168 .. 28 191 .. 26 192 .. 0.97
Alignments for each domain:
== domain 1 score: 149.7 bits; conditional E-value: 7.6e-47
EEEEETTSTTTTS--HHHHHHHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-S CS
MTS 3 tlktlpgvFskdklDkGsklLletlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasd 88
+++t++gvFs ++lD G++lL+e + + +vlDlGcG+G++g+++ ++ + v+++dv+ rA+ +ak+nl+ n+++ +ev++ +
tr|Q5JJF0|Q5JJF0_THEKO 28 KFITASGVFSFGRLDRGTELLIESMVLQPGWRVLDLGCGYGPIGIVASRFVDY--VVMTDVNRRAVSIAKKNLKINGVRnAEVRWGS 112
799**********************************************9999..9***********************9******* PP
TTTTSTTS-EEEEEE---STTTCHCHHHHHHHHHHHHHHHEEEEEEEEEEEETTSCHHHH...HHHHHS--EEEEEESSEEEE CS
MTS 89 vleeveekkfdlivsNPPfhagkatelavaeeliaeAkeaLkegGeLliVanrklgyesl...leelfgnvevvaktkkfkvl 168
++e v+ +kfd i++NPP+hagk+ v +e++ +A+++L++gG L++V+++k+g++ + ++e+f +v+++ak ++++v+
tr|Q5JJF0|Q5JJF0_THEKO 113 LYEPVAGEKFDSIITNPPVHAGKE----VLREIVINAPRHLNDGGYLQLVIKTKQGAKYIkslMDETFTEVRELAKGSGYRVY 191
************************....***************************98876677*******************8 PP
>> tr|Q5JIX8|Q5JIX8_THEKO N5-glutamine methyltransferase, HemK family OS=Thermococcus kodakarensis (strain ATCC BAA-918
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 61.0 0.0 1.4e-19 1.3e-17 20 161 .. 23 177 .. 7 182 .. 0.81
Alignments for each domain:
== domain 1 score: 61.0 bits; conditional E-value: 1.4e-19
HHHHHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTTS-EEEEEE-- CS
MTS 20 sklLletlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdvleeveekkfdlivsNP 105
+ lL+e+l + + +lD+G+G+G++++ la++ v vd++ A+e+a+en++ n++ ve++ sd++e+v+ ++fd+i N
tr|Q5JIX8|Q5JIX8_THEKO 23 TFLLAENLAVKVGDIALDMGTGTGIIALLLARKARW--VLGVDINPLAVELARENARINGIInVEFRLSDLFENVS-GEFDVITFNA 106
779*******99999****************98776..9*********************988*************.*********9 PP
-ST............TTCHCHHHHHHHHHHHHHHHEEEEEEEEEEEETTSCHHHHHHHHHS...--EEEEE CS
MTS 106 Pfh............agkatelavaeeliaeAkeaLkegGeLliVanrklgyeslleelfg...nvevvak 161
P+ g +t +v +++i e + +Lk+gG +iV ++ g+e++l++l + + evvak
tr|Q5JIX8|Q5JIX8_THEKO 107 PYLpgepeepidlalVGGETGREVLDRFIDEVPCYLKPGGVVQIVQSSITGVEETLKRLEKaglTAEVVAK 177
98622222222222245667889********************************7765332225555555 PP
>> tr|Q5JDP7|Q5JDP7_THEKO Predicted DNA methylase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 54.1 0.0 1.8e-17 1.7e-15 23 113 .. 39 128 .. 28 139 .. 0.84
Alignments for each domain:
== domain 1 score: 54.1 bits; conditional E-value: 1.8e-17
HHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTTTSTTS-EEEEEE---S CS
MTS 23 LletlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvleeveekkfdlivsNPPf 107
L++ l + + + ++DlG+G+Gvlg+ + e +v +v+ d++Ale+a+en+++ ++e +e+v+ dv e ++d++++NPPf
tr|Q5JDP7|Q5JDP7_THEKO 39 LAHSLGEVEGKVIADLGAGTGVLGIGAVLLGAE-NVYAVERDKEALEIARENARSLGVEdkIEFVNADVSEFSV--NVDTVIMNPPF 122
4566777778889************99988877.7************************999999999987666..9********** PP
TTTCHC CS
MTS 108 hagkat 113
++ +
tr|Q5JDP7|Q5JDP7_THEKO 123 GSQVKH 128
988764 PP
>> tr|Q5JFS6|Q5JFS6_THEKO Predicted SAM-dependent methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA-918 /
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 41.8 0.0 1.1e-13 1e-11 23 136 .. 49 156 .. 46 171 .. 0.92
Alignments for each domain:
== domain 1 score: 41.8 bits; conditional E-value: 1.1e-13
HHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTTSTTS-EEEEEE---STT CS
MTS 23 LletlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasdvleeveekkfdlivsNPPfha 109
L+e +++e +gkvlD+GcG+Gvl+ ++a ++ v+ vd + + +e++++ + ++++v+ + le ++kfd +v +h+
tr|Q5JFS6|Q5JFS6_THEKO 49 LMEMITDEVKGKVLDVGCGTGVLTFKMALKNGVEMVVGVDRKEEVIEFCNRLGDRVTKNAKFVQGNFLEMGLDEKFDSVVFSYVLHD 135
88999999*************************99****************99999999*********************9888887 PP
TCHCHHHHHHHHHHHHHHHEEEEEEEE CS
MTS 110 gkatelavaeeliaeAkeaLkegGeLl 136
+ e +++ A e+L+egG+ +
tr|Q5JFS6|Q5JFS6_THEKO 136 FEP------EPFLERALEVLEEGGRVI 156
777......889999999999999875 PP
>> tr|Q5JE68|Q5JE68_THEKO 23S rRNA (Uracil-5-)-methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JC
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 38.8 0.0 8.9e-13 8.5e-11 22 114 .. 271 361 .. 255 371 .. 0.86
Alignments for each domain:
== domain 1 score: 38.8 bits; conditional E-value: 8.9e-13
HHHHHCHCC.TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTTSTTS-EEEEEE---S CS
MTS 22 lLletlpke.lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasdvleeveekkfdlivsNPPf 107
lL++++++ + +lDl +G+G g++lak+ + v+ ++ + A+e+a++n+e n++++++ + e+ +k+d++v PP
tr|Q5JE68|Q5JE68_THEKO 271 LLIKAVENFaSGEMILDLYAGVGTFGVWLAKRRFQ--VEGIELNPFAVEIANKNAEINNVDATFKVGRAEETPI-GKYDTVVVDPPR 354
788888888445569****************8877..9************************999999888888.***********6 PP
TTTCHCH CS
MTS 108 hagkate 114
+ k++
tr|Q5JE68|Q5JE68_THEKO 355 KGLKEVA 361
6555544 PP
>> tr|Q5JHF7|Q5JHF7_THEKO 23S rRNA (Uracil-5-)-methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JC
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 38.4 0.0 1.2e-12 1.1e-10 28 128 .. 273 369 .. 248 372 .. 0.81
Alignments for each domain:
== domain 1 score: 38.4 bits; conditional E-value: 1.2e-12
HCC.TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTTSTTS-EEEEEE---STTTCHC CS
MTS 28 pke.lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasdvleeveekkfdlivsNPPfhagkat 113
+ + +kvlDl +G+G g+ lak+ + v+ ++++ A+e+ak+n++ n++++e++ + + + ++d++v PP +ag +
tr|Q5JHF7|Q5JHF7_THEKO 273 AELvEGEKVLDLYSGVGTFGIYLAKRGFK--VEGIEINPFAVEMAKKNAQINGVDAEFRVGEDKDVNSLSEYDTVVVDPP-RAGLH- 355
33346789*****************8877..9***********************9999877666666699*********.66666. PP
HHHHHHHHHHHHHHH CS
MTS 114 elavaeeliaeAkea 128
+++++++++ +e
tr|Q5JHF7|Q5JHF7_THEKO 356 -PKLVRKILKDRPET 369
.67777777766665 PP
>> tr|Q5JGN8|Q5JGN8_THEKO SAM-dependent methyltransferase, UbiE/COQ5 family OS=Thermococcus kodakarensis (strain ATCC B
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 34.0 0.0 2.6e-11 2.5e-09 16 135 .. 27 141 .. 22 143 .. 0.88
Alignments for each domain:
== domain 1 score: 34.0 bits; conditional E-value: 2.6e-11
--HHHHHHHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTTSTTS-EEEEE CS
MTS 16 lDkGsklLletlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasdvleeveekkfdliv 102
+D +++ e + + ++vlDl+cG+G+ +++la++ e v +d + + l++a++ +ea +l+v+++ ++l+ e++fd++
tr|Q5JGN8|Q5JGN8_THEKO 27 IDFVEEIFREDAKR-EVKRVLDLACGTGIPTLELAERGYE--VLGLDLHEEMLRVARRKAEARGLNVKFIRGNALDISFEEEFDAVT 110
55555555555555.4557*****************8887..9******************************************** PP
E---STTTCHCHHHHHHHHHHHHHHHEEEEEEE CS
MTS 103 sNPPfhagkatelavaeeliaeAkeaLkegGeL 135
+ f + ++++++el+++ ++ L++gG +
tr|Q5JGN8|Q5JGN8_THEKO 111 MF--FSSIMYFDDSAIRELFNSVRRTLRPGGVF 141
95..88888999*******************86 PP
>> tr|Q5JJ79|Q5JJ79_THEKO Predicted SAM-dependent methyltransferase, DUF890 family OS=Thermococcus kodakarensis (strain
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 24.3 0.0 2.5e-08 2.4e-06 23 109 .. 74 163 .. 69 174 .. 0.85
2 ! 7.3 0.0 0.0042 0.4 117 167 .. 185 235 .. 176 237 .. 0.88
Alignments for each domain:
== domain 1 score: 24.3 bits; conditional E-value: 2.5e-08
HHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-S..TTTTST..TS-EEEEEE-- CS
MTS 23 LletlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasd..vleeve..ekkfdlivsNP 105
+l+t+ +kvl +G+G ++ a +a++ + +vt+++ d + e ak+n+e+n+++v+ ++s+ ++ v ++fd+i s P
tr|Q5JJ79|Q5JJ79_THEKO 74 FLKTFLR-GGEKVLEIGTGHTAMMALMAERLFNCDVTATELDEEFFEYAKRNIEKNGANVKPIKSNggIIRGVVpkGERFDVIFSAP 159
5666666.5678***********************************************99999983335555423589******** PP
-STT CS
MTS 106 Pfha 109
P+ +
tr|Q5JJ79|Q5JJ79_THEKO 160 PYYE 163
*876 PP
== domain 2 score: 7.3 bits; conditional E-value: 0.0042
HHHHHHHHHHHHEEEEEEEEEEEETTSCHHHHHHHHHS--EEEEEESSEEE CS
MTS 117 vaeeliaeAkeaLkegGeLliVanrklgyeslleelfgnvevvaktkkfkv 167
+li+eA e+L++gG+ + k + ++++e+ +++ +++ kfkv
tr|Q5JJ79|Q5JJ79_THEKO 185 FSVRLIEEALEYLNPGGKVALFLPDKEPLIEAIAEKGKELGYSVRDVKFKV 235
6679*****************999999999999999999988888888887 PP
>> tr|Q5JHQ2|Q5JHQ2_THEKO SAM-dependent methyltransferase, UbiE/COQ5 family OS=Thermococcus kodakarensis (strain ATCC B
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 30.4 0.0 3.3e-10 3.2e-08 22 137 .. 31 140 .. 23 154 .. 0.87
Alignments for each domain:
== domain 1 score: 30.4 bits; conditional E-value: 3.3e-10
HHHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTT.TSTTS-EEEEEE---S CS
MTS 22 lLletlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasdvle.eveekkfdlivsNPPf 107
lL++ +++ +g+vlDl+cG+G + l + e v+ +d++ le a+e +++++ +ve+++ d+ e +e+++fd+++ +
tr|Q5JHQ2|Q5JHQ2_THEKO 31 LLMKFMKT--RGRVLDLACGVGGFSFLLEDLGFE--VVGLDNSRFMLEKAREFAKEKESRVEFIEGDARElPFENDSFDYVLF---I 110
56666666..889*********999999987766..9*******************************99456799******7...5 PP
TTTCHCHHHHHHHHHHHHHHHEEEEEEEEE CS
MTS 108 hagkatelavaeeliaeAkeaLkegGeLli 137
+ + e + ++++e +++Lk+gG++++
tr|Q5JHQ2|Q5JHQ2_THEKO 111 DSLVHFEPQDLAKVFKETARVLKPGGKFIL 140
66667788899999************9875 PP
>> tr|Q5JDR0|Q5JDR0_THEKO SAM-dependent methyltransferase, UPF0020 family OS=Thermococcus kodakarensis (strain ATCC BAA
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 29.7 0.0 5.5e-10 5.3e-08 30 150 .. 126 251 .. 116 262 .. 0.81
Alignments for each domain:
== domain 1 score: 29.7 bits; conditional E-value: 5.5e-10
CTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC....EEEEE-STTTTST...TS-EEEEEE---STT CS
MTS 30 elsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle....vevvasdvleeve...ekkfdlivsNPPfha 109
++ ++vlD + G G+ ++++ k+ v +++d + +e+a+ n + +l ++v++ d++e v+ +++fd+i+ PP +
tr|Q5JDR0|Q5JDR0_THEKO 126 REGETVLDTCMGLGYTAIEASKRGAY--VITIEKDPNVIEIARINPWSRELFtggkIQVIQGDAFEVVKkfkQASFDVIIHDPPRFS 210
36778***************998877..899*************9877776557789999999776554333899*********655 PP
TCHCHHHHHHHHHHHHHHHEEEEEEEE.EEEETTSCHHHH.HH CS
MTS 110 gkatelavaeeliaeAkeaLkegGeLl.iVanrklgyesl.le 150
+ ee+ +e ++Lk+gG+L+ V n +y+++ l+
tr|Q5JDR0|Q5JDR0_THEKO 211 LAG--HLYSEEFYRELFRILKPGGRLFhYVGNPGKKYRRKdLQ 251
554..68899***************984699999999876554 PP
>> tr|Q5JDB4|Q5JDB4_THEKO tRNA/rRNA cytosine-C5-methylase, NOL1/NOP2/Sun family, fused to N-terminal NusB regulator dom
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 2.0 0.0 0.18 18 135 157 .. 17 39 .. 14 46 .. 0.88
2 ! 20.2 0.0 4.7e-07 4.5e-05 17 110 .. 247 342 .. 241 389 .. 0.84
Alignments for each domain:
== domain 1 score: 2.0 bits; conditional E-value: 0.18
EEEEEETTSCHHHHHHHHHS--E CS
MTS 135 LliVanrklgyeslleelfgnve 157
L++V +r+l +++le++f++v+
tr|Q5JDB4|Q5JDB4_THEKO 17 LMLVEERELSSKHALERVFKKVA 39
899*****************986 PP
== domain 2 score: 20.2 bits; conditional E-value: 4.7e-07
-HHHHHHHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.E.EEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTTS-EEEE CS
MTS 17 DkGsklLletlpkelsgkvlDlGcGaGvlgaalakespeae.vtlvdvdarAlesakenleankle.vevvasdvleeveekkfdli 101
D +s+ ++ l+ e +++lDl++ G + ++a+ ++ +++vd ++ l ke ++ +++ v++v+ d+ + +++kfd i
tr|Q5JDB4|Q5JDB4_THEKO 247 DLASAYVAHVLSPEPGERLLDLAAAPGSKTFHAAALMENKGeIVAVDYSYDRLMRMKEKAKVLGVKnVRFVHADGQSFRDKEKFDKI 333
89999999********************99999887665544********************************************* PP
EE---STTT CS
MTS 102 vsNPPfhag 110
+ P ++
tr|Q5JDB4|Q5JDB4_THEKO 334 ILDAPCSSS 342
*99886654 PP
>> tr|Q5JEU8|Q5JEU8_THEKO Predicted SAM-dependent methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA-918 /
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 24.1 0.1 3e-08 2.9e-06 31 91 .. 41 103 .. 31 115 .. 0.85
Alignments for each domain:
== domain 1 score: 24.1 bits; conditional E-value: 3e-08
TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTT CS
MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvle 91
+ g+vlD+++G+Gv g+alak++ +t++d+ + le+ake l+ +++ +++v+ d+ e
tr|Q5JEU8|Q5JEU8_THEKO 41 KGGRVLDICAGTGVAGVALAKATGAKLLTVLDARKDDLELAKEWLKIADINpeLNLVQGDARE 103
4899*********************99****************99988887668888877765 PP
>> tr|Q5JJ78|Q5JJ78_THEKO Probable tRNA/rRNA methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 24.0 0.0 3e-08 2.9e-06 32 139 .. 218 334 .. 207 358 .. 0.73
Alignments for each domain:
== domain 1 score: 24.0 bits; conditional E-value: 3e-08
CSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-S...TTTTST..TS-EEEEEE---STTTC CS
MTS 32 sgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasd...vleeve..ekkfdlivsNPPfhagk 111
+vlD+ + +G ++++a + + ev++vd++ A+++ ken++ n++e ++++ + v+ee+ +kfd+++ PP ++
tr|Q5JJ78|Q5JJ78_THEKO 218 GMRVLDVFTYTGGFAIHAAVAGAD-EVVAVDKSPWAINMVKENAKLNGVEdkMKYIVGSafpVMEEMIkrGEKFDIVILDPPAFVQH 303
5679999999*******9998888.8************************99666655511134443323479*********77777 PP
HCHHHHHHH.H..HHHHHHHEEEEEEEEEEE CS
MTS 112 atelavaee.l..iaeAkeaLkegGeLliVa 139
+++l+ + ++ A +L ++G +l+ a
tr|Q5JJ78|Q5JJ78_THEKO 304 EKDLKRGLRaYfnVNYAGLQLVKEGGILVTA 334
6555443331213455666666666666555 PP
>> tr|Q5JD70|Q5JD70_THEKO Met-10+ like protein OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) OX
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 20.5 0.0 3.7e-07 3.5e-05 32 125 .. 182 265 .. 168 306 .. 0.77
Alignments for each domain:
== domain 1 score: 20.5 bits; conditional E-value: 3.7e-07
CSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTTS-EEEEEE---STTTCHCHHHH CS
MTS 32 sgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdvleeveekkfdlivsNPPfhagkatelav 117
+ v D+ +G+G+ ++ lak+ + v ++d++ A++ +en + nk v + dv + + + k d +++N P
tr|Q5JD70|Q5JD70_THEKO 182 GEIVFDMFAGVGPYSILLAKKAKL--VFACDINPWAVRYLEENKKLNKTPnVIPILGDVRKVAGQIKADRVIMNLPK---------F 257
45589***************8877..99********************998888999****999**********873.........3 PP
HHHHHHHH CS
MTS 118 aeeliaeA 125
a+++++eA
tr|Q5JD70|Q5JD70_THEKO 258 ADRFLKEA 265
44444444 PP
>> tr|Q5JGS7|Q5JGS7_THEKO tRNA (1-methyladenosine) methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA-918
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 18.3 0.0 1.8e-06 0.00017 33 104 .. 95 169 .. 86 211 .. 0.89
Alignments for each domain:
== domain 1 score: 18.3 bits; conditional E-value: 1.8e-06
SEEEEET-TTSHHHHHHHHHT.TC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTTTSTTS-EEEEEE- CS
MTS 33 gkvlDlGcGaGvlgaalakes.peaevtlvdvdarAlesakenleankle..vevvasdvleeveekkfdlivsN 104
++v+ G+G G+l++ la++ p+ +v ++v + e+ak+n+e +++ v + ++++++ ++ek+ d+iv
tr|Q5JGS7|Q5JGS7_THEKO 95 DTVIEAGAGSGALTIFLANAVgPTGKVISYEVRKDFYEIAKKNVELAGFSdrVVLKNKSIYDGIDEKEADHIVLD 169
579999***********987527778***********************9888888999*************976 PP
>> sp|Q5JI54|RSMA_THEKO Probable ribosomal RNA small subunit methyltransferase A OS=Thermococcus kodakarensis (strain A
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 18.0 0.0 2.2e-06 0.00021 31 125 .. 42 131 .. 18 160 .. 0.85
Alignments for each domain:
== domain 1 score: 18.0 bits; conditional E-value: 2.2e-06
TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTTSTTS-EEEEEE---STTTCHCHHHHHH CS
MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasdvleeveekkfdlivsNPPfhagkatelavae 119
++++vl +G G Gvl+ l k+ + v ++++d r +e+ ++ ++ + ve+++ d+l+ +f+ +vsN P++ ++ ++ ++
sp|Q5JI54|RSMA_THEKO 42 EKDTVLEIGPGLGVLTDPLSKRAGK--VYAIEKDCRIVEILRREYNWPN--VEIIEGDALKVEW-PEFNKMVSNLPYQISSPVTFKLLS 125
6778*****************9999..9**************9887666..7999***997555.79*********9999988888877 PP
HHHHHH CS
MTS 120 eliaeA 125
+ ++ A
sp|Q5JI54|RSMA_THEKO 126 REFERA 131
777666 PP
>> tr|Q5JEE1|Q5JEE1_THEKO Protein-L-isoaspartate O-methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA-918
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 17.7 0.0 2.7e-06 0.00026 23 102 .. 69 149 .. 65 152 .. 0.86
Alignments for each domain:
== domain 1 score: 17.7 bits; conditional E-value: 2.7e-06
HHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTST.TS-EEEEE CS
MTS 23 LletlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdvleeve.ekkfdliv 102
+le + + +vl +G+G G +a + + ++ +v ++ + +e+a++nle+ +++ v+v+ d+++ ++ ++ +d i+
tr|Q5JEE1|Q5JEE1_THEKO 69 MLELADLKPGMNVLEIGTGSGWNAALISELVKT-DVYTIERIPELVEFARRNLERAGVKnVHVILGDGTKGFPpKAPYDRII 149
555555667889**********99988887766.8************************************98566799988 PP
>> tr|Q5JEM0|Q5JEM0_THEKO Predicted N6-adenine-specific DNA methylase OS=Thermococcus kodakarensis (strain ATCC BAA-918
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 17.1 0.0 4e-06 0.00038 27 141 .. 213 333 .. 205 355 .. 0.81
Alignments for each domain:
== domain 1 score: 17.1 bits; conditional E-value: 4e-06
CHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTTTST.TS-EEEEEE---S..T CS
MTS 27 lpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvleeve.ekkfdlivsNPPf..h 108
l + g+ +D cG G + ++la + + ++ +++ + ++ a+ n+ + ++ +e+++ d+++ + +++d+ vsN P+ +
tr|Q5JEM0|Q5JEM0_THEKO 213 LAEPNGGSFIDPFCGSGTILIELALRGYKGRIIGLEKYRKHIRGAEMNALSAGVLdkIEFIQGDATKLSQyVESVDFAVSNLPYglK 299
5555788999**************************************998887669*******986555459**********8224 PP
TTC.HCHHHHHHHHHHHHHHHEEEEEEEEEEEET CS
MTS 109 agk.atelavaeeliaeAkeaLkegGeLliVanr 141
g+ + ++ ++++ e ++L++ G ++ ++
tr|Q5JEM0|Q5JEM0_THEKO 300 IGRkSMIPRLYMAFFSELSKVLEKRGVFITTEKK 333
444256678999**************87654443 PP
>> tr|Q5JH73|Q5JH73_THEKO Uncharacterized protein OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 16.8 0.0 5.2e-06 0.00049 32 100 .. 84 151 .. 72 162 .. 0.83
Alignments for each domain:
== domain 1 score: 16.8 bits; conditional E-value: 5.2e-06
CSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTSTTS-EEE CS
MTS 32 sgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle.vevvasdvleeveekkfdl 100
++++D+ cG+G+ + a + ++ +d+d +e+a++n+e+ +++ +e+++ d l+ + +++d+
tr|Q5JH73|Q5JH73_THEKO 84 VESIADVSCGIGIQLIFYAMKVER--AYGIDIDPLKIEFARRNAEKYGVSnIEFINADSLSPETVERVDA 151
4679********999999888887..79*********************99*******998777666664 PP
>> tr|Q5JDP5|Q5JDP5_THEKO tRNA/rRNA cytosine-C5-methylase, NOL1/NOP2/Sun family OS=Thermococcus kodakarensis (strain AT
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 12.3 0.0 0.00012 0.012 27 107 .. 246 331 .. 236 398 .. 0.75
Alignments for each domain:
== domain 1 score: 12.3 bits; conditional E-value: 0.00012
CHCCTCSEEEEET-TTSHHHHHHHHHTTC.E.EEEEESBHHHHHHHHHHHHHTTGC.EEEEE-STTTTST...TS-EEEEEE---S CS
MTS 27 lpkelsgkvlDlGcGaGvlgaalakespeae.vtlvdvdarAlesakenleankle.vevvasdvleeve...ekkfdlivsNPPf 107
l + ++v+Dl++ G +a++a+ ++ + ++dvd + ++ ke l+++++e +ev++ d+ ++ e e+ d ++ P
tr|Q5JDP5|Q5JDP5_THEKO 246 LAPKPGETVVDLAAAPGGKTAHMAELMENRGkIYAFDVDSARIKRMKEVLKRTGVEiAEVIKADGRNAPEllgEEIADRVLLDAPC 331
55557789********9999999998777655************************999999999887654445666665555444 PP
>> tr|Q5JID5|Q5JID5_THEKO N2, N2-dimethylguanosine tRNA methyltransferase OS=Thermococcus kodakarensis (strain ATCC BAA
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 15.0 0.0 1.8e-05 0.0017 26 138 .. 175 292 .. 168 322 .. 0.76
Alignments for each domain:
== domain 1 score: 15.0 bits; conditional E-value: 1.8e-05
HCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC...EEEEE-STTTTST.TS-EEEEEE---ST CS
MTS 26 tlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle...vevvasdvleeve.ekkfdlivsNPPfh 108
+l+k +++++lD GaG + +++ ++v vd+ + +e a++nl++ +++ +++ le++ +kkf+++ + PP+
tr|Q5JID5|Q5JID5_THEKO 175 NLTK-ATREILDPFMGAGGILIEAGLLG--LRVYGVDIRPEMVEGAETNLKHYGVRdytLKLGDATRLEDLFpDKKFEAVATDPPYG 258
4455.56789999999998877777655..559**********************9955444444445554449************9 PP
TTCHCHHHHHHHHHHHH....HHHEEEEEEEEEE CS
MTS 109 agkatelavaeeliaeA....keaLkegGeLliV 138
+ + +el ++A ++L++gG+L i
tr|Q5JID5|Q5JID5_THEKO 259 TAATLAGRKRDELYRKAlrsiYNVLEDGGRLAIA 292
8887666666666655521116799****99986 PP
>> tr|Q5JH54|Q5JH54_THEKO Predicted endonuclease-methyltransferase fusion protein OS=Thermococcus kodakarensis (strain
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -1.3 0.0 1.9 1.8e+02 27 50 .. 413 437 .. 410 450 .. 0.76
2 ? 1.9 0.0 0.2 19 57 88 .. 501 535 .. 492 542 .. 0.76
3 ? 2.0 0.0 0.18 17 96 112 .. 648 664 .. 636 674 .. 0.82
4 ? 4.0 0.0 0.044 4.3 108 142 .. 680 714 .. 678 735 .. 0.75
Alignments for each domain:
== domain 1 score: -1.3 bits; conditional E-value: 1.9
CHCC.TCSEEEEET-TTSHHHHHHH CS
MTS 27 lpke.lsgkvlDlGcGaGvlgaala 50
l+ke ++ kv+Dl++G G ++++
tr|Q5JH54|Q5JH54_THEKO 413 LSKElFEIKVADLASGSGSFLIKVL 437
666667779*********8776665 PP
== domain 2 score: 1.9 bits; conditional E-value: 0.2
EEEEEESBHHHHHHHHHHHHHTTGC...EEEEE-S CS
MTS 57 evtlvdvdarAlesakenleankle...vevvasd 88
+v +vd d +A+e+ak nl ++ ++ +++ +
tr|Q5JH54|Q5JH54_THEKO 501 HVFAVDLDENAVEVAKMNLWRELIKlnpKAFRWDN 535
5889***************9888875555555555 PP
== domain 3 score: 2.0 bits; conditional E-value: 0.18
S-EEEEEE---STTTCH CS
MTS 96 kkfdlivsNPPfhagka 112
+ fd+iv NPP+ + ++
tr|Q5JH54|Q5JH54_THEKO 648 GGFDFIVGNPPYVRIQN 664
579********987655 PP
== domain 4 score: 4.0 bits; conditional E-value: 0.044
TTTCHCHHHHHHHHHHHHHHHEEEEEEEEEEEETT CS
MTS 108 hagkatelavaeeliaeAkeaLkegGeLliVanrk 142
++ ++++++a +i+ + L+egGeL +++ +k
tr|Q5JH54|Q5JH54_THEKO 680 YESAHKNYDLAIPFIERGYNLLREGGELGFIVTKK 714
5667789999******************6555543 PP
>> tr|Q5JFQ4|Q5JFQ4_THEKO SAM-dependent methyltransferase, UbiE/COQ5 family OS=Thermococcus kodakarensis (strain ATCC B
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 9.5 0.0 0.00088 0.085 26 45 .. 34 53 .. 17 62 .. 0.84
2 ? 0.8 0.0 0.41 39 95 137 .. 95 134 .. 89 161 .. 0.76
Alignments for each domain:
== domain 1 score: 9.5 bits; conditional E-value: 0.00088
HCHCCTCSEEEEET-TTSHH CS
MTS 26 tlpkelsgkvlDlGcGaGvl 45
+ ++++g v+D+GcG+G +
tr|Q5JFQ4|Q5JFQ4_THEKO 34 LVAERAKGVVVDVGCGTGNI 53
556668999*********87 PP
== domain 2 score: 0.8 bits; conditional E-value: 0.41
TS-EEEEEE---STTTCHCHHHHHHHHHHHHHHHEEEEEEEEE CS
MTS 95 ekkfdlivsNPPfhagkatelavaeeliaeAkeaLkegGeLli 137
e++ d++vs fh+ + + e i+e ++L++gG L+i
tr|Q5JFQ4|Q5JFQ4_THEKO 95 EGSADTVVSTYAFHHVPD---EEKGEAIREMLRVLRPGGILII 134
577788888888887665...3334556677789999999987 PP
>> tr|Q5JED8|Q5JED8_THEKO SAM-dependent methyltransferase, UbiE/COQ5 family OS=Thermococcus kodakarensis (strain ATCC B
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 10.2 0.0 0.00053 0.051 32 138 .. 160 261 .. 149 282 .. 0.80
Alignments for each domain:
== domain 1 score: 10.2 bits; conditional E-value: 0.00053
CSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STTTTSTTS-EEEEEE---STTTCHCHHHHH CS
MTS 32 sgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasdvleeveekkfdlivsNPPfhagkatelava 118
+vlD+GcG + + +d +++ l++a++ ++ ++l v + + d++ + +++d++++ + +
tr|Q5JED8|Q5JED8_THEKO 160 GMSVLDIGCGSVSPSYFGRLVGYNGFYLGLDYSYALLDIARARIAGEALPVVLKEIDATIIRPVNSYDVVIMSFVLEYI-----QNR 241
55799****986666666655566668899********************999999988888888******97444433.....347 PP
HHHHHHHHHHEEEEEEEEEE CS
MTS 119 eeliaeAkeaLkegGeLliV 138
++ i++A e L+egG+L+iV
tr|Q5JED8|Q5JED8_THEKO 242 KRAIKNALEGLREGGKLVIV 261
8999***************9 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (169 nodes)
Target sequences: 2301 (637680 residues searched)
Passed MSV filter: 84 (0.0365059); expected 46.0 (0.02)
Passed bias filter: 78 (0.0338983); expected 46.0 (0.02)
Passed Vit filter: 30 (0.0130378); expected 2.3 (0.001)
Passed Fwd filter: 24 (0.0104302); expected 0.0 (1e-05)
Initial search space (Z): 2301 [actual number of targets]
Domain search space (domZ): 24 [number of targets reported over threshold]
# CPU time: 0.05u 0.00s 00:00:00.05 Elapsed: 00:00:00.02
# Mc/sec: 5388.40
//
[ok]