# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file:                  pfam_list/MTS.hmm.txt
# target sequence database:        proteomes/Trypanosoma_brucei.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query:       MTS  [M=169]
Accession:   PF05175.13
Description: Methyltransferase small domain
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence               Description
    ------- ------ -----    ------- ------ -----   ---- --  --------               -----------
      2e-13   49.2   0.3    2.8e-10   38.9   0.0    2.5  3  tr|Q389Z0|Q389Z0_TRYB2  Uncharacterized protein OS=Trypanosom
      3e-08   32.4   0.2    4.9e-08   31.7   0.2    1.3  1  tr|Q4GYA9|Q4GYA9_TRYB2  Arginine N-methyltransferase, putativ
    3.5e-07   28.9   0.1       0.33    9.4   0.5    4.0  2  tr|Q381Q6|Q381Q6_TRYB2  Uncharacterized protein OS=Trypanosom
    7.9e-07   27.7   0.0    1.4e-06   27.0   0.0    1.3  1  tr|Q38BP3|Q38BP3_TRYB2  Arginine N-methyltransferase, putativ
    1.5e-06   26.8   0.0    2.6e-06   26.0   0.0    1.3  1  tr|Q4GYR8|Q4GYR8_TRYB2  Uncharacterized protein OS=Trypanosom
    6.3e-06   24.8   0.0      1e-05   24.1   0.0    1.3  1  sp|Q582G4|ANM7_TRYB2    Protein arginine N-methyltransferase 
    0.00031   19.3   0.1    0.00058   18.4   0.1    1.4  1  tr|Q385L0|Q385L0_TRYB2  Uncharacterized protein OS=Trypanosom
     0.0034   15.9   0.0     0.0051   15.3   0.0    1.3  1  tr|Q584S3|Q584S3_TRYB2  Uncharacterized protein OS=Trypanosom
     0.0041   15.7   0.0     0.0062   15.1   0.0    1.3  1  tr|Q38DV8|Q38DV8_TRYB2  Ubiquinone biosynthesis O-methyltrans
  ------ inclusion threshold ------
       0.01   14.3   0.2      0.034   12.6   0.0    1.8  2  tr|Q57Y67|Q57Y67_TRYB2  Uncharacterized protein OS=Trypanosom
      0.012   14.1   0.0      0.021   13.4   0.0    1.3  1  tr|Q57U70|Q57U70_TRYB2  Arginine N-methyltransferase, putativ
      0.025   13.1   0.0      0.042   12.4   0.0    1.4  1  tr|Q38AH9|Q38AH9_TRYB2  Protein-L-isoaspartate, putative OS=T
      0.025   13.1   0.0      0.039   12.4   0.0    1.3  1  tr|Q381M3|Q381M3_TRYB2  Uncharacterized protein OS=Trypanosom
      0.036   12.6   0.0       0.07   11.6   0.0    1.4  1  tr|Q585P9|Q585P9_TRYB2  rRNA adenine N(6)-methyltransferase O
      0.037   12.5   0.0      0.065   11.7   0.0    1.3  1  tr|Q385P4|Q385P4_TRYB2  Uncharacterized protein OS=Trypanosom
      0.039   12.4   0.0       0.15   10.6   0.0    1.8  2  tr|Q4FKJ2|Q4FKJ2_TRYB2  Methyltransferase OS=Trypanosoma bruc
      0.048   12.2   0.1      0.088   11.3   0.1    1.3  1  tr|Q57ZS4|Q57ZS4_TRYB2  Uncharacterized protein OS=Trypanosom
      0.063   11.8   0.0        0.1   11.1   0.0    1.3  1  tr|Q4GZF2|Q4GZF2_TRYB2  Histone-lysine N-methyltransferase, H
       0.07   11.6   0.1       0.13   10.8   0.1    1.4  1  tr|Q38BT8|Q38BT8_TRYB2  Uncharacterized protein OS=Trypanosom
      0.075   11.5   0.0       0.12   10.8   0.0    1.2  1  tr|Q38D36|Q38D36_TRYB2  Uncharacterized protein OS=Trypanosom
       0.09   11.3   0.0       0.19   10.2   0.0    1.5  2  tr|Q38FT0|Q38FT0_TRYB2  Uncharacterized protein OS=Trypanosom
       0.11   11.0   0.0       0.17   10.4   0.0    1.3  1  tr|Q581Z0|Q581Z0_TRYB2  Histone-lysine N-methyltransferase, H


Domain annotation for each sequence (and alignments):
>> tr|Q389Z0|Q389Z0_TRYB2  Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.8   0.0       9.7   3.8e+03     122     138 ..      74      90 ..      59     104 .. 0.66
   2 !   38.9   0.0   7.3e-13   2.8e-10      26      90 ..     204     272 ..     198     279 .. 0.82
   3 !    7.8   0.0    0.0027       1.1      90     108 ..     298     315 ..     276     323 .. 0.75

  Alignments for each domain:
  == domain 1  score: -3.8 bits;  conditional E-value: 9.7
                             HHHHHHHEEEEEEEEEE CS
                     MTS 122 iaeAkeaLkegGeLliV 138
                             + +A+  L++ G+Ll  
  tr|Q389Z0|Q389Z0_TRYB2  74 LPKAPPKLRSAGSLLST 90 
                             34688888888888755 PP

  == domain 2  score: 38.9 bits;  conditional E-value: 7.3e-13
                             HCHCC.TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC...EEEEE-STT CS
                     MTS  26 tlpke.lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle...vevvasdvl 90 
                             ++p++ +  +vlD++cG+G +g+a+ak+ p+a+vt+vd+  +A+ +++en++ n+le     +++sd++
  tr|Q389Z0|Q389Z0_TRYB2 204 KIPETtQPLRVLDMCCGTGCVGIAIAKHVPSAQVTAVDILDEAIGASEENAKLNGLEasrFCTLKSDMF 272
                             5555544457**********************************************9644444555655 PP

  == domain 3  score: 7.8 bits;  conditional E-value: 0.0027
                             TTTSTTS-EEEEEE---ST CS
                     MTS  90 leeveekkfdlivsNPPfh 108
                              +e + ++fd+ivsNPP+ 
  tr|Q389Z0|Q389Z0_TRYB2 298 AAEHA-GSFDIIVSNPPYV 315
                             55555.89*********85 PP

>> tr|Q4GYA9|Q4GYA9_TRYB2  Arginine N-methyltransferase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) 
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   31.7   0.2   1.3e-10   4.9e-08      32     103 ..      54     125 ..      45     126 .. 0.89

  Alignments for each domain:
  == domain 1  score: 31.7 bits;  conditional E-value: 1.3e-10
                             CSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTTTSTTS-EEEEEE CS
                     MTS  32 sgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvleeveekkfdlivs 103
                             ++ vlD+GcG+G+l++ +ak+  + +v  vd ++ A++ a+e +++n++e  +++++  v e   ++k+d+i+s
  tr|Q4GYA9|Q4GYA9_TRYB2  54 DKVVLDVGCGTGILSMFAAKAGAR-KVIGVDCSTVAVQ-AREIVRDNGFEdvITIIQGKVEEIQLDEKVDIIIS 125
                             5679***************98888.899*********8.78999******988999999988888*******97 PP

>> tr|Q381Q6|Q381Q6_TRYB2  Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !    9.4   0.5   0.00086      0.33      57     111 ..      95     173 ..      29     191 .. 0.53
   2 !    6.3   0.0    0.0079       3.1     117     152 ..     200     235 ..     193     243 .. 0.88

  Alignments for each domain:
  == domain 1  score: 9.4 bits;  conditional E-value: 0.00086
                             EEEEEESBHHHHHHHHHHHHHTTGC....................EEEEE-STTTTST....TS-EEEEEE---STTTC CS
                     MTS  57 evtlvdvdarAlesakenleankle....................vevvasdvleeve....ekkfdlivsNPPfhagk 111
                             e ++vdv+  Ale++  ++++++ +                     e  asd++e ++    e  fd+i+ NPP+   +
  tr|Q381Q6|Q381Q6_TRYB2  95 EFHAVDVNPVALEATSITWHNTQKRiiggdtilplhlhrgdlfspFEHEASDITEYTKeekeEFTFDVILFNPPYVPTT 173
                             4555555555555555555555544444444444333333333333333444443333111145688888888876554 PP

  == domain 2  score: 6.3 bits;  conditional E-value: 0.0079
                             HHHHHHHHHHHHEEEEEEEEEEEETTSCHHHHHHHH CS
                     MTS 117 vaeeliaeAkeaLkegGeLliVanrklgyeslleel 152
                             v++++i + +++L++ G  +iVa r+ ++e+l+e +
  tr|Q381Q6|Q381Q6_TRYB2 200 VVDRFISKLPSFLSSRGVCYIVAIRENDVEELMEVI 235
                             7899***************************98865 PP

>> tr|Q38BP3|Q38BP3_TRYB2  Arginine N-methyltransferase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) 
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   27.0   0.0   3.5e-09   1.4e-06      27     103 ..     137     215 ..     133     245 .. 0.82

  Alignments for each domain:
  == domain 1  score: 27.0 bits;  conditional E-value: 3.5e-09
                             CHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC....EEEEE-STTTTSTTS-EEEEEE CS
                     MTS  27 lpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle....vevvasdvleeveekkfdlivs 103
                             l + + ++vl lGcG+G++++ +a+   + +v++vd +a  +++a+  +++n+l+     +    dv+++++ ++fd+i++
  tr|Q38BP3|Q38BP3_TRYB2 137 LRSIKGKSVLHLGCGMGLVSMIAARSLAS-AVVAVDRSAI-VDAAQVVAKKNGLNnisfFRGALVDVVQNFPVRQFDVIIC 215
                             55556788*************99998888.6999998864.88889999999998833444445799999999*******8 PP

>> tr|Q4GYR8|Q4GYR8_TRYB2  Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=TB
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   26.0   0.0   6.8e-09   2.6e-06      30      85 ..     392     448 ..     375     479 .. 0.77

  Alignments for each domain:
  == domain 1  score: 26.0 bits;  conditional E-value: 6.8e-09
                             C...TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEE CS
                     MTS  30 e...lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevv 85 
                             +    + ++lDl+cG+G +g+alak+ ++  v  ++    A++ a+ n+e+n+++  ++
  tr|Q4GYR8|Q4GYR8_TRYB2 392 AeltPETTLLDLCCGTGTIGIALAKHVKR--VIGIELVESAVRDARLNAERNGVRNATF 448
                             245567789****************9999..677777779************9984433 PP

>> sp|Q582G4|ANM7_TRYB2  Protein arginine N-methyltransferase 7 OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   24.1   0.0   2.6e-08     1e-05      26      90 ..      88     153 ..      82     171 .. 0.81

  Alignments for each domain:
  == domain 1  score: 24.1 bits;  conditional E-value: 2.6e-08
                           HCHCC..TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STT CS
                   MTS  26 tlpke..lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasdvl 90 
                            l+k+   +  vl +G+G G+l++++ak   +  v++v+ + +  ++a+en++an++e +v    ++
  sp|Q582G4|ANM7_TRYB2  88 VLKKHvtPETGVLEIGAGSGLLSLMAAKLGAK-WVVAVEGSEELAKLARENIRANNMEHQVKVLHMM 153
                           45555545566*****************9988.699**********************666554444 PP

>> tr|Q385L0|Q385L0_TRYB2  Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   18.4   0.1   1.5e-06   0.00058      33      69 ..     177     213 ..     155     234 .. 0.81

  Alignments for each domain:
  == domain 1  score: 18.4 bits;  conditional E-value: 1.5e-06
                             SEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHH CS
                     MTS  33 gkvlDlGcGaGvlgaalakespeaevtlvdvdarAle 69 
                               v+D+GcG+G ++++l ++s   ++ ++d +a+ l 
  tr|Q385L0|Q385L0_TRYB2 177 IAVADFGCGTGRISCMLSRHSAVGALYCYDSEAAMLG 213
                             459***************************9987765 PP

>> tr|Q584S3|Q584S3_TRYB2  Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.3   0.0   1.3e-05    0.0051      19     103 ..      77     160 ..      64     205 .. 0.81

  Alignments for each domain:
  == domain 1  score: 15.3 bits;  conditional E-value: 1.3e-05
                             HHHHHHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-ST.TTTSTTS-EEEEEE CS
                     MTS  19 GsklLletlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasdv.leeveekkfdlivs 103
                              s+ ++ +lp++ + ++lD G+G+G ++ +l+ +  ++  +l++  a  le ake le   + +++++s++ ++++++k +dliv 
  tr|Q584S3|Q584S3_TRYB2  77 DSRAFICCLPERGTTRALDCGAGIGRITKSLLCHLYDV-TDLLEPVASMLEKAKEELEGFPV-GDFFQSSMeTAKLQPKTYDLIVI 160
                             589999******9999***************9999995.899999999*******9998887.677777662678889*****996 PP

>> tr|Q38DV8|Q38DV8_TRYB2  Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Trypanosoma brucei brucei (stra
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   15.1   0.0   1.6e-05    0.0062      33      74 ..      68     107 ..      57     144 .. 0.79

  Alignments for each domain:
  == domain 1  score: 15.1 bits;  conditional E-value: 1.6e-05
                             SEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHH CS
                     MTS  33 gkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesaken 74 
                              +vlD+GcG G+l+ ++a+   +  v  +d  ++++++a+e 
  tr|Q38DV8|Q38DV8_TRYB2  68 MSVLDVGCGGGILSESIARLGGD--VLGIDMCKESIAVAEER 107
                             579*****************999..55555555555555554 PP

>> tr|Q57Y67|Q57Y67_TRYB2  Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.6   0.0   8.8e-05     0.034      96     145 ..     170     216 ..     160     225 .. 0.80
   2 ?   -1.9   0.2       2.6     1e+03      61      86 ..     413     438 ..     396     456 .. 0.68

  Alignments for each domain:
  == domain 1  score: 12.6 bits;  conditional E-value: 8.8e-05
                             S-EEEEEE---STTTCHCHHHHHHHHHHHHHHHEEEEEEEEE..EEETTSCH CS
                     MTS  96 kkfdlivsNPPfhagkatelavaeeliaeAkeaLkegGeLli..Vanrklgy 145
                             + fd++v  PPf ++     +v+++ i++Ak  L++gG+Ll+  V++++   
  tr|Q57Y67|Q57Y67_TRYB2 170 GAFDYVVADPPFITE-----DVWTAYIQTAKLLLRNGGKLLFttVMENHTML 216
                             579*********765.....56*****************9752266666555 PP

  == domain 2  score: -1.9 bits;  conditional E-value: 2.6
                             EESBHHHHHHHHHHHHHTTGCEEEEE CS
                     MTS  61 vdvdarAlesakenleanklevevva 86 
                              d+ a+A +sa++ ++ n++++ +v 
  tr|Q57Y67|Q57Y67_TRYB2 413 GDNAAEAAASATAAAAVNEVDAALVS 438
                             47778888999999999998855443 PP

>> tr|Q57U70|Q57U70_TRYB2  Arginine N-methyltransferase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) 
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   13.4   0.0   5.3e-05     0.021      31      67 ..      54      87 ..      44     119 .. 0.70

  Alignments for each domain:
  == domain 1  score: 13.4 bits;  conditional E-value: 5.3e-05
                            TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHH CS
                     MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarA 67
                            + + v+D+G+G+G+l++++a++  ++   ++ ++a +
  tr|Q57U70|Q57U70_TRYB2 54 EGKVVVDVGSGTGILSMWAARAGAKH---VFSIEASS 87
                            445699**************998883...33333333 PP

>> tr|Q38AH9|Q38AH9_TRYB2  Protein-L-isoaspartate, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0   0.00011     0.042      23      55 ..      80     112 ..      71     144 .. 0.79

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 0.00011
                             HHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC CS
                     MTS  23 LletlpkelsgkvlDlGcGaGvlgaalakespe 55 
                             Ll+t +  +  +vlD+G+G G+l+a+la+ ++ 
  tr|Q38AH9|Q38AH9_TRYB2  80 LLRTPEGVKPATVLDVGSGSGYLTAVLAELCSG 112
                             555555556678****************98765 PP

>> tr|Q381M3|Q381M3_TRYB2  Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   12.4   0.0    0.0001     0.039      10      75 ..      97     163 ..      92     198 .. 0.81

  Alignments for each domain:
  == domain 1  score: 12.4 bits;  conditional E-value: 0.0001
                             STTTTS--HHHHHHHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.E.EEEEESBHHHHHHHHHHH CS
                     MTS  10 vFskdklDkGsklLletlpkelsgkvlDlGcGaGvlgaalakespeae.vtlvdvdarAlesakenl 75 
                             v ++  lD+ ++l +e l  ++ + vlDl++G+G  ++a+ ++ ++ + +t+ ++     +  ++n+
  tr|Q381M3|Q381M3_TRYB2  97 VKAHYPLDYTTALAVELLGVQQFDLVLDLCAGVGGKSIAISQFLSNSAsLTANEQRGDRCARLRRNI 163
                             5567789**************9999*************99998776554777766655555555555 PP

>> tr|Q585P9|Q585P9_TRYB2  rRNA adenine N(6)-methyltransferase OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.6   0.0   0.00018      0.07      31     112 ..      88     168 ..      75     179 .. 0.85

  Alignments for each domain:
  == domain 1  score: 11.6 bits;  conditional E-value: 0.00018
                             TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTTTSTTS-EEEEEE---STTTCH CS
                     MTS  31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvleeveekkfdlivsNPPfhagka 112
                              ++ vl +G G+G l+ +l+++ ++  v +++vd r ++  ++ ++++ l+  ++v+  ++l++     fd  v N P+  ++a
  tr|Q585P9|Q585P9_TRYB2  88 PTDIVLEIGPGTGNLTEKLLQAAKK--VIAFEVDPRMVAELNKRFQNSPLApkLQVIRGNCLDHEF-PYFDKCVANVPYAISSA 168
                             56679****************9888..999****************9999889*********9988.89*******99876655 PP

>> tr|Q385P4|Q385P4_TRYB2  Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.7   0.0   0.00017     0.065      22      53 ..     223     259 ..     218     271 .. 0.77

  Alignments for each domain:
  == domain 1  score: 11.7 bits;  conditional E-value: 0.00017
                             HHHHHCHCC.....TCSEEEEET-TTSHHHHHHHHHT CS
                     MTS  22 lLletlpke.....lsgkvlDlGcGaGvlgaalakes 53 
                             lLl+ l++        ++++D+G G+G+l+a+la++ 
  tr|Q385P4|Q385P4_TRYB2 223 LLLSLLKHVymtdiDIKTIVDVGGGNGFLAAQLAERL 259
                             555555555444655567***************9976 PP

>> tr|Q4FKJ2|Q4FKJ2_TRYB2  Methyltransferase OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb10.6k1
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.6   0.0   0.00038      0.15      26      86 ..      99     160 ..      93     174 .. 0.76
   2 ?   -1.8   0.0       2.4   9.3e+02     118     138 ..     320     340 ..     317     347 .. 0.84

  Alignments for each domain:
  == domain 1  score: 10.6 bits;  conditional E-value: 0.00038
                             HCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE CS
                     MTS  26 tlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevva 86 
                             + + + +++vlD+GcG+G  + ++ ++++  +v  v+++ + ++ a++  ++ +++  +++++
  tr|Q4FKJ2|Q4FKJ2_TRYB2  99 HAQFKPTDTVLDVGCGIGGPARNMVRFTSC-NVMGVNNNEYQINRARQHDSRYGMSgkINYTK 160
                             555557789**********99999997765.79999999999999999888777774444444 PP

  == domain 2  score: -1.8 bits;  conditional E-value: 2.4
                             HHHHHHHHHHHEEEEEEEEEE CS
                     MTS 118 aeeliaeAkeaLkegGeLliV 138
                             a+e+++e +  L +gGeL i 
  tr|Q4FKJ2|Q4FKJ2_TRYB2 320 ATEILEEGAVNLVKGGELGIF 340
                             57899999999******9775 PP

>> tr|Q57ZS4|Q57ZS4_TRYB2  Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.3   0.1   0.00023     0.088      27      79 ..      87     137 ..      76     152 .. 0.74

  Alignments for each domain:
  == domain 1  score: 11.3 bits;  conditional E-value: 0.00023
                             CHCC.TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTT CS
                     MTS  27 lpke.lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleank 79 
                             l+++ ++ +v+ lG+G+G lg+ la +  +  v+++d +   + + ++n+e nk
  tr|Q57ZS4|Q57ZS4_TRYB2  87 LQNHdKACHVVELGAGVGCLGIGLAMAGAR--VVITDMKE-LVPLMEKNIELNK 137
                             344356678****************98877..77777654.4666666666665 PP

>> tr|Q4GZF2|Q4GZF2_TRYB2  Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Trypanosoma brucei brucei (strai
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   11.1   0.0   0.00026       0.1      28      76 ..     108     155 ..     100     169 .. 0.80

  Alignments for each domain:
  == domain 1  score: 11.1 bits;  conditional E-value: 0.00026
                             HCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHH CS
                     MTS  28 pkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenle 76 
                             + +++++  DlGcG+G +  ++a ++   + + v+++ +  ++ake ++
  tr|Q4GZF2|Q4GZF2_TRYB2 108 NVTADDTFYDLGCGNGSVLFHVALATGA-SCVGVEINEHNAKVAKEAWT 155
                             445677899*********9999987766.78999999999999888765 PP

>> tr|Q38BT8|Q38BT8_TRYB2  Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.1   0.00033      0.13      31      88 ..     227     286 ..     209     304 .. 0.75

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00033
                             TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-S CS
                     MTS  31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasd 88 
                             +++ v+D+ +G+G+ ++ la +     v+++++++++      n+ +nk++  + ++  d
  tr|Q38BT8|Q38BT8_TRYB2 227 KDEVVVDMFAGIGYFTLPLAINGGVKIVHALEKNKYSALYLAFNAVQNKVSdlIVIHCGD 286
                             45679****************999999*******98888888888888887764444333 PP

>> tr|Q38D36|Q38D36_TRYB2  Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.8   0.0   0.00031      0.12      25     102 ..     194     272 ..     189     274 .. 0.81

  Alignments for each domain:
  == domain 1  score: 10.8 bits;  conditional E-value: 0.00031
                             HHCHCCTCSEEEEET-TTSH.HHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC...EEEEE-STTTTSTTS-EEEEE CS
                     MTS  25 etlpkelsgkvlDlGcGaGv.lgaalakespeaevtlvdvdarAlesakenleankle...vevvasdvleeveekkfdliv 102
                             e l +++ g+vl l++G G  +ga     +  +e++++d++a+ l++ +  + +++     v+ v s+ le +++++fd++v
  tr|Q38D36|Q38D36_TRYB2 194 EELLQQTYGRVLELAAGHGQnIGAYP---YAVHEIVMCDANAQQLQAIRYRIPQTAYPkydVRRVRSENLEMFADGEFDCVV 272
                             5566668899*********6366554...445679********99999999888877667799999999**********998 PP

>> tr|Q38FT0|Q38FT0_TRYB2  Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.2   0.0    0.0005      0.19      31      77 ..     135     179 ..     123     191 .. 0.85
   2 ?   -3.7   0.0       9.3   3.6e+03     105     118 ..     239     252 ..     237     253 .. 0.83

  Alignments for each domain:
  == domain 1  score: 10.2 bits;  conditional E-value: 0.0005
                             TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHH CS
                     MTS  31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenlea 77 
                             +++++lDlGc +G+ ++++ k  ++  v+ +d + + +++a++ +++
  tr|Q38FT0|Q38FT0_TRYB2 135 KERRALDLGCAVGASSLEMSKYFSR--VVGIDYSVAFIKMARNVVQS 179
                             7789*****************9988..9999**99999999987664 PP

  == domain 2  score: -3.7 bits;  conditional E-value: 9.3
                             --STTTCHCHHHHH CS
                     MTS 105 PPfhagkatelava 118
                             PP+h+g   +++++
  tr|Q38FT0|Q38FT0_TRYB2 239 PPVHHGDTNDEDIT 252
                             9****999888775 PP

>> tr|Q581Z0|Q581Z0_TRYB2  Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Trypanosoma brucei brucei (strai
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   10.4   0.0   0.00043      0.17      27      76 ..     124     172 ..     114     204 .. 0.76

  Alignments for each domain:
  == domain 1  score: 10.4 bits;  conditional E-value: 0.00043
                             CHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHH CS
                     MTS  27 lpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenle 76 
                             ++ + +++  DlGcG+G +  ++a  +   + + ++++ +  ++ak+ +e
  tr|Q581Z0|Q581Z0_TRYB2 124 MEITSEDTFYDLGCGNGSILFQVAFLTGA-RCVGIEISEHNAKVAKKAWE 172
                             5555677899*********9999876665.67777777777777777665 PP



Internal pipeline statistics summary:
-------------------------------------
Query model(s):                              1  (169 nodes)
Target sequences:                         8561  (4332363 residues searched)
Passed MSV filter:                       265  (0.0309543); expected 171.2 (0.02)
Passed bias filter:                      243  (0.0283845); expected 171.2 (0.02)
Passed Vit filter:                        43  (0.00502278); expected 8.6 (0.001)
Passed Fwd filter:                        22  (0.00256979); expected 0.1 (1e-05)
Initial search space (Z):               8561  [actual number of targets]
Domain search space  (domZ):              22  [number of targets reported over threshold]
# CPU time: 0.10u 0.00s 00:00:00.10 Elapsed: 00:00:00.04
# Mc/sec: 18304.23
//
[ok]