# hmmsearch :: search profile(s) against a sequence database # HMMER 3.1b2 (February 2015); http://hmmer.org/ # Copyright (C) 2015 Howard Hughes Medical Institute. # Freely distributed under the GNU General Public License (GPLv3). # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - # query HMM file: pfam_list/MTS.hmm.txt # target sequence database: proteomes/Trypanosoma_brucei.fasta # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: MTS [M=169] Accession: PF05175.13 Description: Methyltransferase small domain Scores for complete sequences (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Sequence Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- 2e-13 49.2 0.3 2.8e-10 38.9 0.0 2.5 3 tr|Q389Z0|Q389Z0_TRYB2 Uncharacterized protein OS=Trypanosom 3e-08 32.4 0.2 4.9e-08 31.7 0.2 1.3 1 tr|Q4GYA9|Q4GYA9_TRYB2 Arginine N-methyltransferase, putativ 3.5e-07 28.9 0.1 0.33 9.4 0.5 4.0 2 tr|Q381Q6|Q381Q6_TRYB2 Uncharacterized protein OS=Trypanosom 7.9e-07 27.7 0.0 1.4e-06 27.0 0.0 1.3 1 tr|Q38BP3|Q38BP3_TRYB2 Arginine N-methyltransferase, putativ 1.5e-06 26.8 0.0 2.6e-06 26.0 0.0 1.3 1 tr|Q4GYR8|Q4GYR8_TRYB2 Uncharacterized protein OS=Trypanosom 6.3e-06 24.8 0.0 1e-05 24.1 0.0 1.3 1 sp|Q582G4|ANM7_TRYB2 Protein arginine N-methyltransferase 0.00031 19.3 0.1 0.00058 18.4 0.1 1.4 1 tr|Q385L0|Q385L0_TRYB2 Uncharacterized protein OS=Trypanosom 0.0034 15.9 0.0 0.0051 15.3 0.0 1.3 1 tr|Q584S3|Q584S3_TRYB2 Uncharacterized protein OS=Trypanosom 0.0041 15.7 0.0 0.0062 15.1 0.0 1.3 1 tr|Q38DV8|Q38DV8_TRYB2 Ubiquinone biosynthesis O-methyltrans ------ inclusion threshold ------ 0.01 14.3 0.2 0.034 12.6 0.0 1.8 2 tr|Q57Y67|Q57Y67_TRYB2 Uncharacterized protein OS=Trypanosom 0.012 14.1 0.0 0.021 13.4 0.0 1.3 1 tr|Q57U70|Q57U70_TRYB2 Arginine N-methyltransferase, putativ 0.025 13.1 0.0 0.042 12.4 0.0 1.4 1 tr|Q38AH9|Q38AH9_TRYB2 Protein-L-isoaspartate, putative OS=T 0.025 13.1 0.0 0.039 12.4 0.0 1.3 1 tr|Q381M3|Q381M3_TRYB2 Uncharacterized protein OS=Trypanosom 0.036 12.6 0.0 0.07 11.6 0.0 1.4 1 tr|Q585P9|Q585P9_TRYB2 rRNA adenine N(6)-methyltransferase O 0.037 12.5 0.0 0.065 11.7 0.0 1.3 1 tr|Q385P4|Q385P4_TRYB2 Uncharacterized protein OS=Trypanosom 0.039 12.4 0.0 0.15 10.6 0.0 1.8 2 tr|Q4FKJ2|Q4FKJ2_TRYB2 Methyltransferase OS=Trypanosoma bruc 0.048 12.2 0.1 0.088 11.3 0.1 1.3 1 tr|Q57ZS4|Q57ZS4_TRYB2 Uncharacterized protein OS=Trypanosom 0.063 11.8 0.0 0.1 11.1 0.0 1.3 1 tr|Q4GZF2|Q4GZF2_TRYB2 Histone-lysine N-methyltransferase, H 0.07 11.6 0.1 0.13 10.8 0.1 1.4 1 tr|Q38BT8|Q38BT8_TRYB2 Uncharacterized protein OS=Trypanosom 0.075 11.5 0.0 0.12 10.8 0.0 1.2 1 tr|Q38D36|Q38D36_TRYB2 Uncharacterized protein OS=Trypanosom 0.09 11.3 0.0 0.19 10.2 0.0 1.5 2 tr|Q38FT0|Q38FT0_TRYB2 Uncharacterized protein OS=Trypanosom 0.11 11.0 0.0 0.17 10.4 0.0 1.3 1 tr|Q581Z0|Q581Z0_TRYB2 Histone-lysine N-methyltransferase, H Domain annotation for each sequence (and alignments): >> tr|Q389Z0|Q389Z0_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? -3.8 0.0 9.7 3.8e+03 122 138 .. 74 90 .. 59 104 .. 0.66 2 ! 38.9 0.0 7.3e-13 2.8e-10 26 90 .. 204 272 .. 198 279 .. 0.82 3 ! 7.8 0.0 0.0027 1.1 90 108 .. 298 315 .. 276 323 .. 0.75 Alignments for each domain: == domain 1 score: -3.8 bits; conditional E-value: 9.7 HHHHHHHEEEEEEEEEE CS MTS 122 iaeAkeaLkegGeLliV 138 + +A+ L++ G+Ll tr|Q389Z0|Q389Z0_TRYB2 74 LPKAPPKLRSAGSLLST 90 34688888888888755 PP == domain 2 score: 38.9 bits; conditional E-value: 7.3e-13 HCHCC.TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC...EEEEE-STT CS MTS 26 tlpke.lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle...vevvasdvl 90 ++p++ + +vlD++cG+G +g+a+ak+ p+a+vt+vd+ +A+ +++en++ n+le +++sd++ tr|Q389Z0|Q389Z0_TRYB2 204 KIPETtQPLRVLDMCCGTGCVGIAIAKHVPSAQVTAVDILDEAIGASEENAKLNGLEasrFCTLKSDMF 272 5555544457**********************************************9644444555655 PP == domain 3 score: 7.8 bits; conditional E-value: 0.0027 TTTSTTS-EEEEEE---ST CS MTS 90 leeveekkfdlivsNPPfh 108 +e + ++fd+ivsNPP+ tr|Q389Z0|Q389Z0_TRYB2 298 AAEHA-GSFDIIVSNPPYV 315 55555.89*********85 PP >> tr|Q4GYA9|Q4GYA9_TRYB2 Arginine N-methyltransferase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 31.7 0.2 1.3e-10 4.9e-08 32 103 .. 54 125 .. 45 126 .. 0.89 Alignments for each domain: == domain 1 score: 31.7 bits; conditional E-value: 1.3e-10 CSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTTTSTTS-EEEEEE CS MTS 32 sgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvleeveekkfdlivs 103 ++ vlD+GcG+G+l++ +ak+ + +v vd ++ A++ a+e +++n++e +++++ v e ++k+d+i+s tr|Q4GYA9|Q4GYA9_TRYB2 54 DKVVLDVGCGTGILSMFAAKAGAR-KVIGVDCSTVAVQ-AREIVRDNGFEdvITIIQGKVEEIQLDEKVDIIIS 125 5679***************98888.899*********8.78999******988999999988888*******97 PP >> tr|Q381Q6|Q381Q6_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 9.4 0.5 0.00086 0.33 57 111 .. 95 173 .. 29 191 .. 0.53 2 ! 6.3 0.0 0.0079 3.1 117 152 .. 200 235 .. 193 243 .. 0.88 Alignments for each domain: == domain 1 score: 9.4 bits; conditional E-value: 0.00086 EEEEEESBHHHHHHHHHHHHHTTGC....................EEEEE-STTTTST....TS-EEEEEE---STTTC CS MTS 57 evtlvdvdarAlesakenleankle....................vevvasdvleeve....ekkfdlivsNPPfhagk 111 e ++vdv+ Ale++ ++++++ + e asd++e ++ e fd+i+ NPP+ + tr|Q381Q6|Q381Q6_TRYB2 95 EFHAVDVNPVALEATSITWHNTQKRiiggdtilplhlhrgdlfspFEHEASDITEYTKeekeEFTFDVILFNPPYVPTT 173 4555555555555555555555544444444444333333333333333444443333111145688888888876554 PP == domain 2 score: 6.3 bits; conditional E-value: 0.0079 HHHHHHHHHHHHEEEEEEEEEEEETTSCHHHHHHHH CS MTS 117 vaeeliaeAkeaLkegGeLliVanrklgyeslleel 152 v++++i + +++L++ G +iVa r+ ++e+l+e + tr|Q381Q6|Q381Q6_TRYB2 200 VVDRFISKLPSFLSSRGVCYIVAIRENDVEELMEVI 235 7899***************************98865 PP >> tr|Q38BP3|Q38BP3_TRYB2 Arginine N-methyltransferase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 27.0 0.0 3.5e-09 1.4e-06 27 103 .. 137 215 .. 133 245 .. 0.82 Alignments for each domain: == domain 1 score: 27.0 bits; conditional E-value: 3.5e-09 CHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC....EEEEE-STTTTSTTS-EEEEEE CS MTS 27 lpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle....vevvasdvleeveekkfdlivs 103 l + + ++vl lGcG+G++++ +a+ + +v++vd +a +++a+ +++n+l+ + dv+++++ ++fd+i++ tr|Q38BP3|Q38BP3_TRYB2 137 LRSIKGKSVLHLGCGMGLVSMIAARSLAS-AVVAVDRSAI-VDAAQVVAKKNGLNnisfFRGALVDVVQNFPVRQFDVIIC 215 55556788*************99998888.6999998864.88889999999998833444445799999999*******8 PP >> tr|Q4GYR8|Q4GYR8_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=TB # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 26.0 0.0 6.8e-09 2.6e-06 30 85 .. 392 448 .. 375 479 .. 0.77 Alignments for each domain: == domain 1 score: 26.0 bits; conditional E-value: 6.8e-09 C...TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEE CS MTS 30 e...lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevv 85 + + ++lDl+cG+G +g+alak+ ++ v ++ A++ a+ n+e+n+++ ++ tr|Q4GYR8|Q4GYR8_TRYB2 392 AeltPETTLLDLCCGTGTIGIALAKHVKR--VIGIELVESAVRDARLNAERNGVRNATF 448 245567789****************9999..677777779************9984433 PP >> sp|Q582G4|ANM7_TRYB2 Protein arginine N-methyltransferase 7 OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 24.1 0.0 2.6e-08 1e-05 26 90 .. 88 153 .. 82 171 .. 0.81 Alignments for each domain: == domain 1 score: 24.1 bits; conditional E-value: 2.6e-08 HCHCC..TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-STT CS MTS 26 tlpke..lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasdvl 90 l+k+ + vl +G+G G+l++++ak + v++v+ + + ++a+en++an++e +v ++ sp|Q582G4|ANM7_TRYB2 88 VLKKHvtPETGVLEIGAGSGLLSLMAAKLGAK-WVVAVEGSEELAKLARENIRANNMEHQVKVLHMM 153 45555545566*****************9988.699**********************666554444 PP >> tr|Q385L0|Q385L0_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 18.4 0.1 1.5e-06 0.00058 33 69 .. 177 213 .. 155 234 .. 0.81 Alignments for each domain: == domain 1 score: 18.4 bits; conditional E-value: 1.5e-06 SEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHH CS MTS 33 gkvlDlGcGaGvlgaalakespeaevtlvdvdarAle 69 v+D+GcG+G ++++l ++s ++ ++d +a+ l tr|Q385L0|Q385L0_TRYB2 177 IAVADFGCGTGRISCMLSRHSAVGALYCYDSEAAMLG 213 459***************************9987765 PP >> tr|Q584S3|Q584S3_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.3 0.0 1.3e-05 0.0051 19 103 .. 77 160 .. 64 205 .. 0.81 Alignments for each domain: == domain 1 score: 15.3 bits; conditional E-value: 1.3e-05 HHHHHHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGCEEEEE-ST.TTTSTTS-EEEEEE CS MTS 19 GsklLletlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleanklevevvasdv.leeveekkfdlivs 103 s+ ++ +lp++ + ++lD G+G+G ++ +l+ + ++ +l++ a le ake le + +++++s++ ++++++k +dliv tr|Q584S3|Q584S3_TRYB2 77 DSRAFICCLPERGTTRALDCGAGIGRITKSLLCHLYDV-TDLLEPVASMLEKAKEELEGFPV-GDFFQSSMeTAKLQPKTYDLIVI 160 589999******9999***************9999995.899999999*******9998887.677777662678889*****996 PP >> tr|Q38DV8|Q38DV8_TRYB2 Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Trypanosoma brucei brucei (stra # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ! 15.1 0.0 1.6e-05 0.0062 33 74 .. 68 107 .. 57 144 .. 0.79 Alignments for each domain: == domain 1 score: 15.1 bits; conditional E-value: 1.6e-05 SEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHH CS MTS 33 gkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesaken 74 +vlD+GcG G+l+ ++a+ + v +d ++++++a+e tr|Q38DV8|Q38DV8_TRYB2 68 MSVLDVGCGGGILSESIARLGGD--VLGIDMCKESIAVAEER 107 579*****************999..55555555555555554 PP >> tr|Q57Y67|Q57Y67_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.6 0.0 8.8e-05 0.034 96 145 .. 170 216 .. 160 225 .. 0.80 2 ? -1.9 0.2 2.6 1e+03 61 86 .. 413 438 .. 396 456 .. 0.68 Alignments for each domain: == domain 1 score: 12.6 bits; conditional E-value: 8.8e-05 S-EEEEEE---STTTCHCHHHHHHHHHHHHHHHEEEEEEEEE..EEETTSCH CS MTS 96 kkfdlivsNPPfhagkatelavaeeliaeAkeaLkegGeLli..Vanrklgy 145 + fd++v PPf ++ +v+++ i++Ak L++gG+Ll+ V++++ tr|Q57Y67|Q57Y67_TRYB2 170 GAFDYVVADPPFITE-----DVWTAYIQTAKLLLRNGGKLLFttVMENHTML 216 579*********765.....56*****************9752266666555 PP == domain 2 score: -1.9 bits; conditional E-value: 2.6 EESBHHHHHHHHHHHHHTTGCEEEEE CS MTS 61 vdvdarAlesakenleanklevevva 86 d+ a+A +sa++ ++ n++++ +v tr|Q57Y67|Q57Y67_TRYB2 413 GDNAAEAAASATAAAAVNEVDAALVS 438 47778888999999999998855443 PP >> tr|Q57U70|Q57U70_TRYB2 Arginine N-methyltransferase, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 13.4 0.0 5.3e-05 0.021 31 67 .. 54 87 .. 44 119 .. 0.70 Alignments for each domain: == domain 1 score: 13.4 bits; conditional E-value: 5.3e-05 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHH CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarA 67 + + v+D+G+G+G+l++++a++ ++ ++ ++a + tr|Q57U70|Q57U70_TRYB2 54 EGKVVVDVGSGTGILSMWAARAGAKH---VFSIEASS 87 445699**************998883...33333333 PP >> tr|Q38AH9|Q38AH9_TRYB2 Protein-L-isoaspartate, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 0.00011 0.042 23 55 .. 80 112 .. 71 144 .. 0.79 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.00011 HHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC CS MTS 23 LletlpkelsgkvlDlGcGaGvlgaalakespe 55 Ll+t + + +vlD+G+G G+l+a+la+ ++ tr|Q38AH9|Q38AH9_TRYB2 80 LLRTPEGVKPATVLDVGSGSGYLTAVLAELCSG 112 555555556678****************98765 PP >> tr|Q381M3|Q381M3_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 12.4 0.0 0.0001 0.039 10 75 .. 97 163 .. 92 198 .. 0.81 Alignments for each domain: == domain 1 score: 12.4 bits; conditional E-value: 0.0001 STTTTS--HHHHHHHHHCHCCTCSEEEEET-TTSHHHHHHHHHTTC.E.EEEEESBHHHHHHHHHHH CS MTS 10 vFskdklDkGsklLletlpkelsgkvlDlGcGaGvlgaalakespeae.vtlvdvdarAlesakenl 75 v ++ lD+ ++l +e l ++ + vlDl++G+G ++a+ ++ ++ + +t+ ++ + ++n+ tr|Q381M3|Q381M3_TRYB2 97 VKAHYPLDYTTALAVELLGVQQFDLVLDLCAGVGGKSIAISQFLSNSAsLTANEQRGDRCARLRRNI 163 5567789**************9999*************99998776554777766655555555555 PP >> tr|Q585P9|Q585P9_TRYB2 rRNA adenine N(6)-methyltransferase OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX= # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.6 0.0 0.00018 0.07 31 112 .. 88 168 .. 75 179 .. 0.85 Alignments for each domain: == domain 1 score: 11.6 bits; conditional E-value: 0.00018 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-STTTTSTTS-EEEEEE---STTTCH CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasdvleeveekkfdlivsNPPfhagka 112 ++ vl +G G+G l+ +l+++ ++ v +++vd r ++ ++ ++++ l+ ++v+ ++l++ fd v N P+ ++a tr|Q585P9|Q585P9_TRYB2 88 PTDIVLEIGPGTGNLTEKLLQAAKK--VIAFEVDPRMVAELNKRFQNSPLApkLQVIRGNCLDHEF-PYFDKCVANVPYAISSA 168 56679****************9888..999****************9999889*********9988.89*******99876655 PP >> tr|Q385P4|Q385P4_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.7 0.0 0.00017 0.065 22 53 .. 223 259 .. 218 271 .. 0.77 Alignments for each domain: == domain 1 score: 11.7 bits; conditional E-value: 0.00017 HHHHHCHCC.....TCSEEEEET-TTSHHHHHHHHHT CS MTS 22 lLletlpke.....lsgkvlDlGcGaGvlgaalakes 53 lLl+ l++ ++++D+G G+G+l+a+la++ tr|Q385P4|Q385P4_TRYB2 223 LLLSLLKHVymtdiDIKTIVDVGGGNGFLAAQLAERL 259 555555555444655567***************9976 PP >> tr|Q4FKJ2|Q4FKJ2_TRYB2 Methyltransferase OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb10.6k1 # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.6 0.0 0.00038 0.15 26 86 .. 99 160 .. 93 174 .. 0.76 2 ? -1.8 0.0 2.4 9.3e+02 118 138 .. 320 340 .. 317 347 .. 0.84 Alignments for each domain: == domain 1 score: 10.6 bits; conditional E-value: 0.00038 HCHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE CS MTS 26 tlpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevva 86 + + + +++vlD+GcG+G + ++ ++++ +v v+++ + ++ a++ ++ +++ +++++ tr|Q4FKJ2|Q4FKJ2_TRYB2 99 HAQFKPTDTVLDVGCGIGGPARNMVRFTSC-NVMGVNNNEYQINRARQHDSRYGMSgkINYTK 160 555557789**********99999997765.79999999999999999888777774444444 PP == domain 2 score: -1.8 bits; conditional E-value: 2.4 HHHHHHHHHHHEEEEEEEEEE CS MTS 118 aeeliaeAkeaLkegGeLliV 138 a+e+++e + L +gGeL i tr|Q4FKJ2|Q4FKJ2_TRYB2 320 ATEILEEGAVNLVKGGELGIF 340 57899999999******9775 PP >> tr|Q57ZS4|Q57ZS4_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.3 0.1 0.00023 0.088 27 79 .. 87 137 .. 76 152 .. 0.74 Alignments for each domain: == domain 1 score: 11.3 bits; conditional E-value: 0.00023 CHCC.TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTT CS MTS 27 lpke.lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleank 79 l+++ ++ +v+ lG+G+G lg+ la + + v+++d + + + ++n+e nk tr|Q57ZS4|Q57ZS4_TRYB2 87 LQNHdKACHVVELGAGVGCLGIGLAMAGAR--VVITDMKE-LVPLMEKNIELNK 137 344356678****************98877..77777654.4666666666665 PP >> tr|Q4GZF2|Q4GZF2_TRYB2 Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Trypanosoma brucei brucei (strai # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 11.1 0.0 0.00026 0.1 28 76 .. 108 155 .. 100 169 .. 0.80 Alignments for each domain: == domain 1 score: 11.1 bits; conditional E-value: 0.00026 HCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHH CS MTS 28 pkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenle 76 + +++++ DlGcG+G + ++a ++ + + v+++ + ++ake ++ tr|Q4GZF2|Q4GZF2_TRYB2 108 NVTADDTFYDLGCGNGSVLFHVALATGA-SCVGVEINEHNAKVAKEAWT 155 445677899*********9999987766.78999999999999888765 PP >> tr|Q38BT8|Q38BT8_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.1 0.00033 0.13 31 88 .. 227 286 .. 209 304 .. 0.75 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00033 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC..EEEEE-S CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenleankle..vevvasd 88 +++ v+D+ +G+G+ ++ la + v+++++++++ n+ +nk++ + ++ d tr|Q38BT8|Q38BT8_TRYB2 227 KDEVVVDMFAGIGYFTLPLAINGGVKIVHALEKNKYSALYLAFNAVQNKVSdlIVIHCGD 286 45679****************999999*******98888888888888887764444333 PP >> tr|Q38D36|Q38D36_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.8 0.0 0.00031 0.12 25 102 .. 194 272 .. 189 274 .. 0.81 Alignments for each domain: == domain 1 score: 10.8 bits; conditional E-value: 0.00031 HHCHCCTCSEEEEET-TTSH.HHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHHTTGC...EEEEE-STTTTSTTS-EEEEE CS MTS 25 etlpkelsgkvlDlGcGaGv.lgaalakespeaevtlvdvdarAlesakenleankle...vevvasdvleeveekkfdliv 102 e l +++ g+vl l++G G +ga + +e++++d++a+ l++ + + +++ v+ v s+ le +++++fd++v tr|Q38D36|Q38D36_TRYB2 194 EELLQQTYGRVLELAAGHGQnIGAYP---YAVHEIVMCDANAQQLQAIRYRIPQTAYPkydVRRVRSENLEMFADGEFDCVV 272 5566668899*********6366554...445679********99999999888877667799999999**********998 PP >> tr|Q38FT0|Q38FT0_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.2 0.0 0.0005 0.19 31 77 .. 135 179 .. 123 191 .. 0.85 2 ? -3.7 0.0 9.3 3.6e+03 105 118 .. 239 252 .. 237 253 .. 0.83 Alignments for each domain: == domain 1 score: 10.2 bits; conditional E-value: 0.0005 TCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHHH CS MTS 31 lsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenlea 77 +++++lDlGc +G+ ++++ k ++ v+ +d + + +++a++ +++ tr|Q38FT0|Q38FT0_TRYB2 135 KERRALDLGCAVGASSLEMSKYFSR--VVGIDYSVAFIKMARNVVQS 179 7789*****************9988..9999**99999999987664 PP == domain 2 score: -3.7 bits; conditional E-value: 9.3 --STTTCHCHHHHH CS MTS 105 PPfhagkatelava 118 PP+h+g +++++ tr|Q38FT0|Q38FT0_TRYB2 239 PPVHHGDTNDEDIT 252 9****999888775 PP >> tr|Q581Z0|Q581Z0_TRYB2 Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Trypanosoma brucei brucei (strai # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- 1 ? 10.4 0.0 0.00043 0.17 27 76 .. 124 172 .. 114 204 .. 0.76 Alignments for each domain: == domain 1 score: 10.4 bits; conditional E-value: 0.00043 CHCCTCSEEEEET-TTSHHHHHHHHHTTC.EEEEEESBHHHHHHHHHHHH CS MTS 27 lpkelsgkvlDlGcGaGvlgaalakespeaevtlvdvdarAlesakenle 76 ++ + +++ DlGcG+G + ++a + + + ++++ + ++ak+ +e tr|Q581Z0|Q581Z0_TRYB2 124 MEITSEDTFYDLGCGNGSILFQVAFLTGA-RCVGIEISEHNAKVAKKAWE 172 5555677899*********9999876665.67777777777777777665 PP Internal pipeline statistics summary: ------------------------------------- Query model(s): 1 (169 nodes) Target sequences: 8561 (4332363 residues searched) Passed MSV filter: 265 (0.0309543); expected 171.2 (0.02) Passed bias filter: 243 (0.0283845); expected 171.2 (0.02) Passed Vit filter: 43 (0.00502278); expected 8.6 (0.001) Passed Fwd filter: 22 (0.00256979); expected 0.1 (1e-05) Initial search space (Z): 8561 [actual number of targets] Domain search space (domZ): 22 [number of targets reported over threshold] # CPU time: 0.10u 0.00s 00:00:00.10 Elapsed: 00:00:00.04 # Mc/sec: 18304.23 // [ok]