# hmmsearch :: search profile(s) against a sequence database
# HMMER 3.1b2 (February 2015); http://hmmer.org/
# Copyright (C) 2015 Howard Hughes Medical Institute.
# Freely distributed under the GNU General Public License (GPLv3).
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
# query HMM file: pfam_list/MafB19-deam.hmm.txt
# target sequence database: proteomes/Dictyostelium_discoideum.fasta
# - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: MafB19-deam [M=138]
Accession: PF14437.5
Description: MafB19-like deaminase
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
1.8e-21 75.9 0.2 3.6e-21 74.9 0.0 1.7 2 tr|Q54JE5|Q54JE5_DICDI Adenosine deaminase, tRNA-specific OS
1.2e-14 53.8 0.1 1.8e-14 53.2 0.1 1.2 1 tr|Q54JJ1|Q54JJ1_DICDI CMP/dCMP deaminase, zinc-binding doma
1.7e-11 43.6 0.1 2.3e-11 43.1 0.1 1.3 1 tr|Q8T1Z7|Q8T1Z7_DICDI Uncharacterized protein OS=Dictyostel
3.1e-11 42.7 0.2 3.9e-11 42.4 0.2 1.2 1 tr|Q86JM0|Q86JM0_DICDI Uncharacterized protein OS=Dictyostel
2.7e-10 39.6 0.1 3.7e-10 39.2 0.1 1.2 1 tr|Q54SW5|Q54SW5_DICDI Uncharacterized protein OS=Dictyostel
1.1e-09 37.6 0.1 1.6e-09 37.1 0.1 1.2 1 tr|Q559S7|Q559S7_DICDI Uncharacterized protein OS=Dictyostel
1.8e-09 37.0 0.1 2.7e-09 36.4 0.1 1.3 1 tr|Q54SS3|Q54SS3_DICDI Uncharacterized protein OS=Dictyostel
3e-09 36.3 0.1 4.5e-09 35.7 0.1 1.2 1 tr|Q54DP5|Q54DP5_DICDI Uncharacterized protein OS=Dictyostel
3.2e-09 36.2 12.7 4.2e-09 35.8 4.0 3.1 2 tr|Q54XN0|Q54XN0_DICDI Cytidine deaminase-like protein OS=Di
7.8e-07 28.4 0.9 1.5e-06 27.5 0.8 1.5 1 tr|Q54DQ7|Q54DQ7_DICDI Uncharacterized protein OS=Dictyostel
1.6e-06 27.5 0.0 6.1e-06 25.6 0.0 2.0 1 tr|Q54M63|Q54M63_DICDI Uncharacterized protein OS=Dictyostel
------ inclusion threshold ------
0.078 12.2 0.1 0.14 11.5 0.1 1.3 1 tr|Q54ZU8|Q54ZU8_DICDI Uncharacterized protein OS=Dictyostel
Domain annotation for each sequence (and alignments):
>> tr|Q54JE5|Q54JE5_DICDI Adenosine deaminase, tRNA-specific OS=Dictyostelium discoideum OX=44689 GN=DDB0230178 PE=4 SV
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -3.4 0.0 4.8 5.1e+03 85 107 .. 10 32 .. 8 42 .. 0.63
2 ! 74.9 0.0 3.4e-24 3.6e-21 2 116 .. 46 171 .. 45 222 .. 0.89
Alignments for each domain:
== domain 1 score: -3.4 bits; conditional E-value: 4.8
MafB19-deam 85 Cagaivqaglkklvygagnpksl 107
C i++ + k ++ + k++
tr|Q54JE5|Q54JE5_DICDI 10 CCNKIINESIEKETRKQYYIKTV 32
55677777777766666665554 PP
== domain 2 score: 74.9 bits; conditional E-value: 3.4e-24
MafB19-deam 2 dkekafrkalaevekatkikedkigavivkdkkviargsnekelnakataHaEiaalqqAa......kklkskrlddatlyvtlepC 82
+++k+++ a++e ka+k +e+++++viv ++++iargsn+++ +++ t HaE +a+ q + +k++ l+++ lyvt+epC
tr|Q54JE5|Q54JE5_DICDI 46 NHKKFMEAAIEEGYKALKEGEVPVACVIVYKGEIIARGSNKTNIKKNGTRHAELEAFDQIFlnkelnDRFKDSLLEECDLYVTVEPC 132
899*****************************************************99974333333789***************** PP
MafB19-deam 83 dmCagaivqaglkklvygagnpks.....lnkLkvkekn 116
mC a+ ++k++ +g+ n k+ + +L+++ ++
tr|Q54JE5|Q54JE5_DICDI 133 LMCSVALQFCKIKRVFFGCHNDKFggngsVYELNFSPIS 171
***********************9888886666666544 PP
>> tr|Q54JJ1|Q54JJ1_DICDI CMP/dCMP deaminase, zinc-binding domain-containing protein OS=Dictyostelium discoideum OX=446
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 53.2 0.1 1.7e-17 1.8e-14 7 111 .. 50 151 .. 45 164 .. 0.80
Alignments for each domain:
== domain 1 score: 53.2 bits; conditional E-value: 1.7e-17
MafB19-deam 7 frkalaevekatkike.dkigavivkdkkviargsnekelnakataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaivqa 92
++ +++v + +k k+ ++ ++ k++ i + n + ++ t+HaEi ++q+A + ++ +d tly+t e C mC gai ++
tr|Q54JJ1|Q54JJ1_DICDI 50 HQGYMQQVIDFAKEKGaLFVASIVHKNGTQIVIDMNLGRQMKDLTQHAEIVVIQKANALYGISNFSDYTLYTTGESCLMCQGAILYS 136
55555555554444440445668888888888888888889********************************************** PP
MafB19-deam 93 glkklvygagnpkslnkLk 111
g k+vyg++ ++ L
tr|Q54JJ1|Q54JJ1_DICDI 137 GFSKVVYGTS----IKTLY 151
*********9....66665 PP
>> tr|Q8T1Z7|Q8T1Z7_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0168546 PE=4 SV=2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 43.1 0.1 2.1e-14 2.3e-11 6 102 .. 50 144 .. 39 190 .. 0.79
Alignments for each domain:
== domain 1 score: 43.1 bits; conditional E-value: 2.1e-14
MafB19-deam 6 afrkalaevekatkikedkigavivkdkkviargsnekelnakataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaivqa 92
+++k ++ + + + ++ k ga iv+++ +a + + H+E++a++ + k ++ + +d +y+t epC+mC ai+
tr|Q8T1Z7|Q8T1Z7_DICDI 50 FHEKYMKIAIDVAVENNSKFGAAIVHKNGTLACTGV--NIGGSRMYHGEVKAIMNCTSKYAKATWEDYYMYTTGEPCPMCSAAIMWT 134
444555555555555667888877755555555444..46788999***************************************** PP
MafB19-deam 93 glkklvygag 102
+ +k+++++
tr|Q8T1Z7|Q8T1Z7_DICDI 135 KFQKVIFASY 144
*****99876 PP
>> tr|Q86JM0|Q86JM0_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0168627 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 42.4 0.2 3.7e-14 3.9e-11 8 102 .. 53 145 .. 46 191 .. 0.85
Alignments for each domain:
== domain 1 score: 42.4 bits; conditional E-value: 3.7e-14
MafB19-deam 8 rkala.evekatkikedkigavivkdkkviargsnekelnakataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaivqag 93
+k ++ + +a++ +++ ++a++ k++ v +g n + + H+E++a++ + ++ + +d ly+t epC+mC ai+ +
tr|Q86JM0|Q86JM0_DICDI 53 SKYMQiAIDIAIENNSKFAAAIVHKNGTVACTGVN---VGGSRMYHGEVKAIMNCTTMYQQATWEDYSLYTTGEPCPMCSAAIMWTK 136
444441457789999999999*99**********9...778999******************************************* PP
MafB19-deam 94 lkklvygag 102
+k+++++
tr|Q86JM0|Q86JM0_DICDI 137 FQKVIFASY 145
****99876 PP
>> tr|Q54SW5|Q54SW5_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0205171 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 39.2 0.1 3.5e-13 3.7e-10 11 102 .. 58 148 .. 49 186 .. 0.82
Alignments for each domain:
== domain 1 score: 39.2 bits; conditional E-value: 3.5e-13
MafB19-deam 11 laevekatkikedkiga.vivkdkkviargsnekelnakataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaivqaglkk 96
+ + + tk+ ++k ga + ++ + +g n ++ +a H+Ei a+ ++ ++++ ++ ly+t epC+mC ai+ a+ k
tr|Q54SW5|Q54SW5_DICDI 58 MRVAIDVTKAINQKFGAaIFHSNGTLMCTGVN--TGQTSAILHGEIRAILNCSELYGKTTWEGYYLYTTGEPCPMCSAAIMWAKFDK 142
55555556666677777355688899999999..77899************************************************ PP
MafB19-deam 97 lvygag 102
+++++
tr|Q54SW5|Q54SW5_DICDI 143 VIFASY 148
*99876 PP
>> tr|Q559S7|Q559S7_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0217008 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 37.1 0.1 1.5e-12 1.6e-09 13 102 .. 72 159 .. 60 177 .. 0.84
Alignments for each domain:
== domain 1 score: 37.1 bits; conditional E-value: 1.5e-12
MafB19-deam 13 evekatkikedkigavivkdkkviargsnekelnakataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaivqaglkklvy 99
+ ka++ +++ +a++ k++ + ++ n e + H+Ei a+ ++ ++ + +d +y+t epC+mC a+ + k+++
tr|Q559S7|Q559S7_DICDI 72 ALDKAIEHNSKFGAAIVHKNGTLMCTAANTGE--GSRILHGEIRAILNCTQLYQQETWEDYYMYTTGEPCPMCSAALLWTKFEKVIF 156
346788888888888999**********9555..77889**********************************************99 PP
MafB19-deam 100 gag 102
g+
tr|Q559S7|Q559S7_DICDI 157 GSF 159
975 PP
>> tr|Q54SS3|Q54SS3_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0205299 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 36.4 0.1 2.5e-12 2.7e-09 3 101 .. 48 144 .. 46 186 .. 0.83
Alignments for each domain:
== domain 1 score: 36.4 bits; conditional E-value: 2.5e-12
MafB19-deam 3 kekafrkalaevekatkikedkiga.vivkdkkviargsnekelnakataHaEiaalqqAakklkskrlddatlyvtlepCdmCaga 88
++++++k + + + + ++ k ga ++ k++ + +g n + + H+E++a++ ++ ++ + +d ly+t epC+mC a
tr|Q54SS3|Q54SS3_DICDI 48 DQQFHAKYMRIAINVAVENNSKFGAaIVHKNGTLMCTGAN---TGGSRMYHGEVKAIMNCTDLYGKATWEDHYLYTTGEPCPMCSAA 131
67777777776666555566666663777999999***99...5668999**********************************999 PP
MafB19-deam 89 ivqaglkklvyga 101
+ + k+++++
tr|Q54SS3|Q54SS3_DICDI 132 AMWTKFDKVIFAS 144
8888888888765 PP
>> tr|Q54DP5|Q54DP5_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0184221 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 35.7 0.1 4.3e-12 4.5e-09 15 112 .. 72 167 .. 58 174 .. 0.82
Alignments for each domain:
== domain 1 score: 35.7 bits; conditional E-value: 4.3e-12
MafB19-deam 15 ekatkikedkigavivkdkkviargsnekelnakataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaivqaglkklvyga 101
+a +++++ ++ + +++ + g n ++ + +H+Ei a++ + + + + tly+ epC mC a+ a+ k++v g+
tr|Q54DP5|Q54DP5_DICDI 72 AIAKQQNKKFVASIYHQNGTLMCLGVN--TGKPNIISHGEIVAINNCTALHGITSFTNYTLYTSGEPCAMCSAALLWADFKTIVWGT 156
345555566666699999999999999..6678899***********99999999******************************** PP
MafB19-deam 102 gnpkslnkLkv 112
n + l k+ +
tr|Q54DP5|Q54DP5_DICDI 157 FNSDLLCKICM 167
99998877665 PP
>> tr|Q54XN0|Q54XN0_DICDI Cytidine deaminase-like protein OS=Dictyostelium discoideum OX=44689 GN=DDB0230180 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -3.0 1.5 3.8 4e+03 12 48 .. 10 46 .. 3 62 .. 0.63
2 ! 35.8 4.0 3.9e-12 4.2e-09 5 129 .. 295 512 .. 292 515 .. 0.84
Alignments for each domain:
== domain 1 score: -3.0 bits; conditional E-value: 3.8
MafB19-deam 12 aevekatkikedkigavivkdkkviargsnekelnak 48
+e+ + ++ + d+ ++i ++++ + +n+ke n++
tr|Q54XN0|Q54XN0_DICDI 10 NEMTQQSETNLDINTKIIDDNNNINKSENNKKESNKQ 46
5555556666666666666666666666665555544 PP
== domain 2 score: 35.8 bits; conditional E-value: 3.9e-12
MafB19-deam 5 kafrkalaevekatkikedkigaviv..kdkkviargsn................................................ 41
k+++ a++++e++ k +++ igav + + +k++a+ +
tr|Q54XN0|Q54XN0_DICDI 295 KYMSLAIEQAEIGKKRGHKGIGAVLIdpNTNKIVATSYDqtnrisvdetpeisetqyispiishcimtitnklsteqvddikkqmke 381
788888999999999999999996664578899999988889999999999999999999999999999999999999999999999 PP
MafB19-deam 42 ....................................ekelnakataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaivqa 92
eke +++ + E + l l++ + + l++t+epC mC a+v +
tr|Q54XN0|Q54XN0_DICDI 382 qkkfekekqfenrnenenknenkneneicndndeekEKEEKEEKEEKEECNILSFV--NLGQYLATNFHLFITKEPCIMCSMALVHS 466
99999999999999888888888888888888888777777777788888888766..889999999******************** PP
MafB19-deam 93 glkklvygagnpks.....lnkLkvkekngrvelv....eddckei 129
++k++vyg++ ++ l+ + k n+r+e+ ed+ck++
tr|Q54XN0|Q54XN0_DICDI 467 RVKRVVYGSSSRDGglgsyLKIHTEKSLNHRFEVYkdfmEDECKKL 512
**********9999*9776666666778*****9999999999876 PP
>> tr|Q54DQ7|Q54DQ7_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0184210 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 27.5 0.8 1.4e-09 1.5e-06 6 90 .. 69 150 .. 65 164 .. 0.84
Alignments for each domain:
== domain 1 score: 27.5 bits; conditional E-value: 1.4e-09
MafB19-deam 6 afrkalaevekatkikedkiga.vivkdkkviargsnekelnakataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaiv 90
++++++a + + +k++ +k ++ + +++ + g n ++ + H+E+aa++ + + ++tly+t epC mC+ iv
tr|Q54DQ7|Q54DQ7_DICDI 69 MHEHRMAYILAISKQTRRKFVTsIYAQNGTLLCHGVN--TGKPNLMTHGEVAAINNCTSLYNISSYTNMTLYTTGEPCAMCL--IV 150
5666677777777777888777677899999999999..6778999***************9999****************4..54 PP
>> tr|Q54M63|Q54M63_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0186844 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 25.6 0.0 5.7e-09 6.1e-06 5 110 .. 69 165 .. 62 175 .. 0.81
Alignments for each domain:
== domain 1 score: 25.6 bits; conditional E-value: 5.7e-09
MafB19-deam 5 kafrkalaevekatkikedkigaviv.kdkkviargsnekelnakataHaEiaalqqAakklkskrlddatlyvtlepCdmCagaiv 90
++f+k++ e +a+k +++k + +iv d++v+ +g ke +a H E a+ + k + ++ t+y t ep + aiv
tr|Q54M63|Q54M63_DICDI 69 EMFMKIALE--IAIK-SKVKFVSIIVsPDDRVLCSGIFSKE---NAILHSELVAITNCSSSHKMVTFENHTIYSTAEPDSLSSSAIV 149
444444433..3333.4555555555499********9666...899**************************************** PP
MafB19-deam 91 qaglkklvygagnpkslnkL 110
a+ k++vyg++ ++ L
tr|Q54M63|Q54M63_DICDI 150 WARFKQVVYGSS----IKHL 165
**********99....6555 PP
>> tr|Q54ZU8|Q54ZU8_DICDI Uncharacterized protein OS=Dictyostelium discoideum OX=44689 GN=DDB0217955 PE=4 SV=1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? 11.5 0.1 0.00013 0.14 10 86 .. 67 145 .. 59 150 .. 0.76
Alignments for each domain:
== domain 1 score: 11.5 bits; conditional E-value: 0.00013
MafB19-deam 10 alaev.ekatkikedkigavivkdkkviargsnekelnakataHaEiaalqqAakklkskrlddatlyv...tlepCdmCa 86
++a v +a +++++ ++ + +++ + g n ++ + +H+Ei a++ + + + + tly+ +C++C
tr|Q54ZU8|Q54ZU8_DICDI 67 RMAYVlAIAKQQNKKFVASIYHQNGTLMCLGVN--TGKPNIISHGEIVAINNCTALHGITSFTNYTLYTsggNDLLCKICM 145
555441345555566666699999999999999..6678899***********99999999*******9443367899995 PP
Internal pipeline statistics summary:
-------------------------------------
Query model(s): 1 (138 nodes)
Target sequences: 12739 (6856946 residues searched)
Passed MSV filter: 775 (0.0608368); expected 254.8 (0.02)
Passed bias filter: 238 (0.0186828); expected 254.8 (0.02)
Passed Vit filter: 25 (0.00196248); expected 12.7 (0.001)
Passed Fwd filter: 12 (0.000941989); expected 0.1 (1e-05)
Initial search space (Z): 12739 [actual number of targets]
Domain search space (domZ): 12 [number of targets reported over threshold]
# CPU time: 0.10u 0.00s 00:00:00.10 Elapsed: 00:00:00.05
# Mc/sec: 18925.17
//
[ok]